ABIN1673385

antibody from antibodies-online

Targeting: CSF3R CD114, GCSFR

Western blot (Recommended by provider)

Antibody Data

Product number

ABIN1673385

Provider

antibodies-online

Product name

anti-Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) (Middle Region) antibody

Antibody type

Polyclonal

Antigen

A synthetic peptide corresponding to a sequence in the middle region of human CSF3R.Immunogen affinity purified.

Reactivity

Human

Host

Rabbit

Epitope

Middle Region

Isotype

IgG

Vial size

100 μg

Storage

At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

An activating mutation in the CSF3R gene induces a hereditary chronic neutrophilia.

Plo I, Zhang Y, Le Couédic JP, Nakatake M, Boulet JM, Itaya M, Smith SO, Debili N, Constantinescu SN, Vainchenker W, Louache F, de Botton S
The Journal of experimental medicine 2009 Aug 3;206(8):1701-7

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The carboxyl terminus of the granulocyte colony-stimulating factor receptor, truncated in patients with severe congenital neutropenia/acute myeloid leukemia, is required for SH2-containing phosphatase-1 suppression of Stat activation.

Dong F, Qiu Y, Yi T, Touw IP, Larner AC
Journal of immunology (Baltimore, Md. : 1950) 2001 Dec 1;167(11):6447-52

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Assignment of the human granulocyte colony-stimulating factor receptor gene (CSF3R) to chromosome 1 at region p35-p34.3.

Inazawa J, Fukunaga R, Seto Y, Nakagawa H, Misawa S, Abe T, Nagata S
Genomics 1991 Aug;10(4):1075-8