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- References [13]
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- Product number
- 19793-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#19793-1-AP, RRID:AB_10638922
- Product name
- CCT6A-Specific antibody
- Antibody type
- Polyclonal
- Description
- CCT6A-Specific antibody (Cat. #19793-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Construction and validation of a prognostic model based on mitochondria-associated endoplasmic reticulum membranes gene signature in LUAD patients.
Exosomal CCT6A Secreted by Cancer-Associated Fibroblasts Interacts with β-Catenin to Enhance Chemoresistance and Tumorigenesis in Gastric Cancer.
ANKRD55 is a key regulator of T cell inflammation in multiple sclerosis.
Tumor-derived exosomal CCT6A serves as a matchmaker introducing chemokines to tumor-associated macrophages in pancreatic ductal adenocarcinoma.
Chaperonin-containing tailless complex polypeptide 1 subunit 6A negatively regulates autophagy and protects colorectal cancer cells from cisplatin-induced cytotoxicity.
In situ analysis reveals the TRiC duty cycle and PDCD5 as an open-state cofactor.
CCT6A functions as promising diagnostic biomarker and promotes cell proliferation in colorectal cancer.
CCT6A facilitates lung adenocarcinoma progression and glycolysis via STAT1/HK2 axis.
CCT6A is associated with CDC20, Enneking stage and prognosis in osteosarcoma, and its knockdown suppresses osteosarcoma cell viability and invasion.
Albumosomes formed by cytoplasmic pre-folding albumin maintain mitochondrial homeostasis and inhibit nonalcoholic fatty liver disease.
CCT2 is an aggrephagy receptor for clearance of solid protein aggregates.
Proteomics Profiling of Autologous Blood and Semen Exosomes from HIV-infected and Uninfected Individuals Reveals Compositional and Functional Variabilities.
Molecular chaperone CCT3 supports proper mitotic progression and cell proliferation in hepatocellular carcinoma cells.
Zhang Q, Fu C, Liu S, Leng Y, Duan L, Wang N, Zhang L, Qiao H
PloS one 2025;20(9):e0330722
PloS one 2025;20(9):e0330722
Exosomal CCT6A Secreted by Cancer-Associated Fibroblasts Interacts with β-Catenin to Enhance Chemoresistance and Tumorigenesis in Gastric Cancer.
Sun H, Zhang T, Zhang X, Liu Y, Wang X, Wang X, Tan C, Ni S, Weng W, Zhang M, Wang L, Huang D, Wang X, Wang W, Sheng W, Xu MD
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(38):e06674
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(38):e06674
ANKRD55 is a key regulator of T cell inflammation in multiple sclerosis.
Wu C, Jiang M, Yang X, Liu Y, Huang B, Guo Y, Cao R, Cui Z, Deng G, Wang W, Guo M, Lin Z, Fan J, Zhang LM, Di Cesare Mannelli L, Pang T, Wang C, Zhang CJ
The Journal of clinical investigation 2025 Oct 15;135(20)
The Journal of clinical investigation 2025 Oct 15;135(20)
Tumor-derived exosomal CCT6A serves as a matchmaker introducing chemokines to tumor-associated macrophages in pancreatic ductal adenocarcinoma.
Ma T, Guo WW, Zhang M, He W, Dongzhi C, Gongye X, Xia P, Chai Y, Chen Z, Zhu Y, Qu C, Liu J, Yang Z, Ma W, Tian M, Yuan Y
Cell death & disease 2025 May 15;16(1):382
Cell death & disease 2025 May 15;16(1):382
Chaperonin-containing tailless complex polypeptide 1 subunit 6A negatively regulates autophagy and protects colorectal cancer cells from cisplatin-induced cytotoxicity.
Ma JX, Li XJ, Li YL, Liu MC, Du RH, Cheng Y, Li LJ, Ai ZY, Jiang JT, Yan SY
World journal of gastroenterology 2025 May 14;31(18):105729
World journal of gastroenterology 2025 May 14;31(18):105729
In situ analysis reveals the TRiC duty cycle and PDCD5 as an open-state cofactor.
Xing H, Rosenkranz RRE, Rodriguez-Aliaga P, Lee TT, Majtner T, Böhm S, Turoňová B, Frydman J, Beck M
Nature 2025 Jan;637(8047):983-990
Nature 2025 Jan;637(8047):983-990
CCT6A functions as promising diagnostic biomarker and promotes cell proliferation in colorectal cancer.
Ma J, Wei Q, Zhang L, Sun F, Li W, Du R, Liu M, Yan S, Wang C
Journal of Cancer 2024;15(18):5897-5909
Journal of Cancer 2024;15(18):5897-5909
CCT6A facilitates lung adenocarcinoma progression and glycolysis via STAT1/HK2 axis.
Yu SK, Yu T, Wang YM, Sun A, Liu J, Lu KH
Journal of translational medicine 2024 May 15;22(1):460
Journal of translational medicine 2024 May 15;22(1):460
CCT6A is associated with CDC20, Enneking stage and prognosis in osteosarcoma, and its knockdown suppresses osteosarcoma cell viability and invasion.
Wang N, Chen Y, Wu J
Oncology letters 2023 May;25(5):201
Oncology letters 2023 May;25(5):201
Albumosomes formed by cytoplasmic pre-folding albumin maintain mitochondrial homeostasis and inhibit nonalcoholic fatty liver disease.
Ma B, Ju A, Zhang S, An Q, Xu S, Liu J, Yu L, Fu Y, Luo Y
Signal transduction and targeted therapy 2023 Jun 16;8(1):229
Signal transduction and targeted therapy 2023 Jun 16;8(1):229
CCT2 is an aggrephagy receptor for clearance of solid protein aggregates.
Ma X, Lu C, Chen Y, Li S, Ma N, Tao X, Li Y, Wang J, Zhou M, Yan YB, Li P, Heydari K, Deng H, Zhang M, Yi C, Ge L
Cell 2022 Apr 14;185(8):1325-1345.e22
Cell 2022 Apr 14;185(8):1325-1345.e22
Proteomics Profiling of Autologous Blood and Semen Exosomes from HIV-infected and Uninfected Individuals Reveals Compositional and Functional Variabilities.
Kaddour H, Lyu Y, Welch JL, Paromov V, Mandape SN, Sakhare SS, Pandhare J, Stapleton JT, Pratap S, Dash C, Okeoma CM
Molecular & cellular proteomics : MCP 2020 Jan;19(1):78-100
Molecular & cellular proteomics : MCP 2020 Jan;19(1):78-100
Molecular chaperone CCT3 supports proper mitotic progression and cell proliferation in hepatocellular carcinoma cells.
Zhang Y, Wang Y, Wei Y, Wu J, Zhang P, Shen S, Saiyin H, Wumaier R, Yang X, Wang C, Yu L
Cancer letters 2016 Mar 1;372(1):101-9
Cancer letters 2016 Mar 1;372(1):101-9
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The CCT6A-Specific antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human CCT6A-Specific. This antibody recognizes human, mouse antigen. The CCT6A-Specific antibody has been validated for the following applications: ELISA, WB analysis.
