Antibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 19430-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- HUWE1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated HUWE1 antibody (Cat. #19430-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Phosphorylated SHMT2 Regulates Oncogenesis Through m(6)A Modification in Lung Adenocarcinoma.
Overcoming therapeutic resistance in oncolytic herpes virotherapy by targeting IGF2BP3-induced NETosis in malignant glioma.
DOCK1 insufficiency disrupts trophoblast function and pregnancy outcomes via DUSP4-ERK pathway.
The role of USP7 in the Shoc2-ERK1/2 signaling axis and Noonan-like syndrome with loose anagen hair.
WNK1 is an assembly factor for the human ER membrane protein complex.
Genomic gain of RRS1 promotes hepatocellular carcinoma through reducing the RPL11-MDM2-p53 signaling.
NEDD4L-mediated LTF protein degradation limits ferroptosis.
HUWE1 promotes EGFR ubiquitination and degradation to protect against renal tubulointerstitial fibrosis.
Ubiquitination and inhibition of glycine receptor by HUWE1 in spinal cord dorsal horn.
Derlin-1 promotes ubiquitylation and degradation of the epithelial Na(+) channel, ENaC.
Han T, Wang Y, Cheng M, Hu Q, Wan X, Huang M, Liu Y, Xun W, Xu J, Wang L, Luo R, Yuan Y, Wang K, Wang J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 May;11(18):e2307834
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 May;11(18):e2307834
Overcoming therapeutic resistance in oncolytic herpes virotherapy by targeting IGF2BP3-induced NETosis in malignant glioma.
Dai W, Tian R, Yu L, Bian S, Chen Y, Yin B, Luan Y, Chen S, Fan Z, Yan R, Pan X, Hou Y, Li R, Chen J, Shu M
Nature communications 2024 Jan 2;15(1):131
Nature communications 2024 Jan 2;15(1):131
DOCK1 insufficiency disrupts trophoblast function and pregnancy outcomes via DUSP4-ERK pathway.
Xu Y, Liu X, Zeng W, Zhu Y, Dong J, Wu F, Chen C, Sharma S, Lin Y
Life science alliance 2024 Feb;7(2)
Life science alliance 2024 Feb;7(2)
The role of USP7 in the Shoc2-ERK1/2 signaling axis and Noonan-like syndrome with loose anagen hair.
Wilson P, Abdelmoti L, Norcross R, Jang ER, Palayam M, Galperin E
Journal of cell science 2021 Nov 1;134(21)
Journal of cell science 2021 Nov 1;134(21)
WNK1 is an assembly factor for the human ER membrane protein complex.
Pleiner T, Hazu M, Tomaleri GP, Januszyk K, Oania RS, Sweredoski MJ, Moradian A, Guna A, Voorhees RM
Molecular cell 2021 Jul 1;81(13):2693-2704.e12
Molecular cell 2021 Jul 1;81(13):2693-2704.e12
Genomic gain of RRS1 promotes hepatocellular carcinoma through reducing the RPL11-MDM2-p53 signaling.
Cao P, Yang A, Li P, Xia X, Han Y, Zhou G, Wang R, Yang F, Li Y, Zhang Y, Cui Y, Ji H, Lu L, He F, Zhou G
Science advances 2021 Aug;7(35)
Science advances 2021 Aug;7(35)
NEDD4L-mediated LTF protein degradation limits ferroptosis.
Wang Y, Liu Y, Liu J, Kang R, Tang D
Biochemical and biophysical research communications 2020 Oct 22;531(4):581-587
Biochemical and biophysical research communications 2020 Oct 22;531(4):581-587
HUWE1 promotes EGFR ubiquitination and degradation to protect against renal tubulointerstitial fibrosis.
Zhu Q, Dong H, Bukhari AA, Zhao A, Li M, Sun Y, Zhang X, Cao C, Su D, Liang X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):4591-4601
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):4591-4601
Ubiquitination and inhibition of glycine receptor by HUWE1 in spinal cord dorsal horn.
Zhang ZY, Guo Z, Li HL, He YT, Duan XL, Suo ZW, Yang X, Hu XD
Neuropharmacology 2019 Apr;148:358-365
Neuropharmacology 2019 Apr;148:358-365
Derlin-1 promotes ubiquitylation and degradation of the epithelial Na(+) channel, ENaC.
You H, Ge Y, Zhang J, Cao Y, Xing J, Su D, Huang Y, Li M, Qu S, Sun F, Liang X
Journal of cell science 2017 Mar 15;130(6):1027-1036
Journal of cell science 2017 Mar 15;130(6):1027-1036
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- WB result of HUWE1 antibody (19430-1-AP, 1:1000) with 293 cells by Dr. Emilia Galperin, University of Kentucky.
- Other comments
- WB