CABT-B1800

antibody from Creative Diagnostics

Targeting: HUWE1 Ib772, KIAA0312, UREB1

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

CABT-B1800

Provider

Creative Diagnostics

Product name

Anti-HUWE1 polyclonal antibody

Antibody type

Polyclonal

Description

E3 ubiquitin-protein ligase HUWE1, also known as, ARF-binding protein 1 (ARF-BP1) or HECT, UBA and WWE domain-containing protein 1 or Homologous to E6AP carboxyl terminus homologous protein 9 (HectH9) or Large structure of UREB1 (LASU1) or Mcl-1 ubiquitin ligase E3 (Mule) or Upstream regulatory element-binding protein 1 (URE-B1 or URE-binding protein 1), and encoded by the gene names HUWE1 or UREB1 or HSPC272, mediates ubiquitination and subsequent proteasomal degradation of target proteins and regulates apoptosis by catalyzing the polyubiquitination and degradation of MCL1. HUWEI is mainly expressed in the cytoplasm of most tissues, except in the nucleus of spermatogonia, primary spermatocytes and neuronal cells.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 _L

Concentration

Please refer to lot specific datasheet.

Storage

Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.