Explore
Validate
Learn
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations [0]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 66302-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- CHCHD2 antibody
- Antibody type
- Monoclonal
- Description
- KD/KO validated CHCHD2 antibody (Cat. #66302-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, pig, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Rat, Porcine
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 2G1G10
- Vial size
- 20ul, 150ul
Submitted references A nucleolar long "non-coding" RNA encodes a novel protein that functions in response to stress.
The CHCHD2/Sirt1 corepressors involve in G9a-mediated regulation of RNase H1 expression to control R-loop.
Discovery of bactericides as an acute mitochondrial membrane damage inducer.
Reduced erythrocytic CHCHD2 mRNA is associated with brain pathology of Parkinson's disease.
Loss of CHCHD2 and CHCHD10 activates OMA1 peptidase to disrupt mitochondrial cristae phenocopying patient mutations.
Mitochondrial Nuclear Retrograde Regulator 1 (MNRR1) rescues the cellular phenotype of MELAS by inducing homeostatic mechanisms.
CHCHD2 accumulates in distressed mitochondria and facilitates oligomerization of CHCHD10.
Loss of CHCHD10-CHCHD2 complexes required for respiration underlies the pathogenicity of a CHCHD10 mutation in ALS.
Feng S, Desotell A, Ross A, Jovanovic M, Manley JL
Proceedings of the National Academy of Sciences of the United States of America 2023 Feb 28;120(9):e2221109120
Proceedings of the National Academy of Sciences of the United States of America 2023 Feb 28;120(9):e2221109120
The CHCHD2/Sirt1 corepressors involve in G9a-mediated regulation of RNase H1 expression to control R-loop.
Li L, Wu Y, Dai K, Wang Q, Ye S, Shi Q, Chen Z, Huang YC, Zhao W, Li L
Cell insight 2023 Aug;2(4):100112
Cell insight 2023 Aug;2(4):100112
Discovery of bactericides as an acute mitochondrial membrane damage inducer.
Houston R, Sekine Y, Larsen MB, Murakami K, Mullett SJ, Wendell SG, Narendra DP, Chen BB, Sekine S
Molecular biology of the cell 2021 Nov 1;32(21):ar32
Molecular biology of the cell 2021 Nov 1;32(21):ar32
Reduced erythrocytic CHCHD2 mRNA is associated with brain pathology of Parkinson's disease.
Liu X, Wang Q, Yang Y, Stewart T, Shi M, Soltys D, Liu G, Thorland E, Cilento EM, Hou Y, Liu Z, Feng T, Zhang J
Acta neuropathologica communications 2021 Mar 8;9(1):37
Acta neuropathologica communications 2021 Mar 8;9(1):37
Loss of CHCHD2 and CHCHD10 activates OMA1 peptidase to disrupt mitochondrial cristae phenocopying patient mutations.
Liu YT, Huang X, Nguyen D, Shammas MK, Wu BP, Dombi E, Springer DA, Poulton J, Sekine S, Narendra DP
Human molecular genetics 2020 Jun 3;29(9):1547-1567
Human molecular genetics 2020 Jun 3;29(9):1547-1567
Mitochondrial Nuclear Retrograde Regulator 1 (MNRR1) rescues the cellular phenotype of MELAS by inducing homeostatic mechanisms.
Aras S, Purandare N, Gladyck S, Somayajulu-Nitu M, Zhang K, Wallace DC, Grossman LI
Proceedings of the National Academy of Sciences of the United States of America 2020 Dec 15;117(50):32056-32065
Proceedings of the National Academy of Sciences of the United States of America 2020 Dec 15;117(50):32056-32065
CHCHD2 accumulates in distressed mitochondria and facilitates oligomerization of CHCHD10.
Huang X, Wu BP, Nguyen D, Liu YT, Marani M, Hench J, Bénit P, Kozjak-Pavlovic V, Rustin P, Frank S, Narendra DP
Human molecular genetics 2018 Nov 15;27(22):3881-3900
Human molecular genetics 2018 Nov 15;27(22):3881-3900
Loss of CHCHD10-CHCHD2 complexes required for respiration underlies the pathogenicity of a CHCHD10 mutation in ALS.
Straub IR, Janer A, Weraarpachai W, Zinman L, Robertson J, Rogaeva E, Shoubridge EA
Human molecular genetics 2018 Jan 1;27(1):178-189
Human molecular genetics 2018 Jan 1;27(1):178-189
No comments: Submit comment
No validations: Submit validation data