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Protein structure
DPM2
Dolichyl-phosphate mannosyltransferase subunit 2, regulatoryMGC111193, MGC21559
Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. The protein encoded by this gene is a hydrophobic protein that contains 2 predicted transmembrane domains and a putative ER localization signal near the C terminus. This protein associates with DPM1 in vivo and is required for the ER localization and stable expression of DPM1 and also enhances the binding of dolichol-phosphate to DPM1. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Invitrogen Antibodies |  PA5-71442 |
1 references | Polyclonal |
WB
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| Novus Biologicals | NBP1-28470 |
1 references | Polyclonal |
EL
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| Acris Antibodies GmbH | AP51312PU-N |
Polyclonal |
WB
EL
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| antibodies-online | ABIN4306023 |
Polyclonal |
IHC
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| Atlas Antibodies | HPA064623 |
Polyclonal |
IHC
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