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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [7]
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- Product number
- ABIN401268 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Fanconi Anemia, Complementation Group C (FANCC) (AA 96-112) antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide corresponding to amino acids 96-112 of Human FANCCAA Sequence: 1 maqdsvdlsc dyqfwmqkls vwdqastlet qqdtclhvaq fqeflrkmye alkemdsntv61 ierfptigql lakacwnpfi laydesqkil iwclcclink epqnsgqskl nswiqgvlsh121 ilsalrfdke valftqglgy apidyypgll knmvlslase lrenhlngfn tqrrmaperv181 aslsrvcvpl itltdvdplv eallichgre pqeilqpeff eavneaillk kislpmsavv241 clwlrhlpsl ekamlhlfek lissernclr riecfikdss lpqaachpai frvvdemfrc301 alletdgale iiatiqvftq cfvealekas kqlrfalkty fpytspslam vllqdpqdip361 rghwlqtlkh isellreave dqthgscggp feswflfihf ggwaemvaeq llmsaaeppt421 allwllafyy gprdgrqqra qtmvqvkavl ghllamsrss slsaqdlqtv agqgtdtdlr481 apaqqlirhl llnfllwapg ghtiawdvit lmahtaeith eiigfldqtl yrwnrlgies541 prseklarel lkelrtqvRemarks: 558 aa, predicted MW 63. 4 kDa
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 1.45 mg/ml (by UV absorbance at 280 nm)
- Storage
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoidrepeated freezing and thawing. Should this product contain a precipitate we recommendmicrocentrifugation before use. Shelf life: one year from despatch.
Submitted references Functional relationships of FANCC to homologous recombination, translesion synthesis, and BLM.
The Fanconi anemia core complex associates with chromatin during S phase.
The Fanconi anemia proteins functionally interact with the protein kinase regulated by RNA (PKR).
Fanconi anemia C gene product regulates expression of genes involved in differentiation and inflammation.
Regulation of the Fanconi anemia group C protein through proteolytic modification.
The Fanconi anaemia gene FANCC promotes homologous recombination and error-prone DNA repair.
Evidence for at least four Fanconi anaemia genes including FACC on chromosome 9.
Hirano S, Yamamoto K, Ishiai M, Yamazoe M, Seki M, Matsushita N, Ohzeki M, Yamashita YM, Arakawa H, Buerstedde JM, Enomoto T, Takeda S, Thompson LH, Takata M
The EMBO journal 2005 Jan 26;24(2):418-27
The EMBO journal 2005 Jan 26;24(2):418-27
The Fanconi anemia core complex associates with chromatin during S phase.
Mi J, Kupfer GM
Blood 2005 Jan 15;105(2):759-66
Blood 2005 Jan 15;105(2):759-66
The Fanconi anemia proteins functionally interact with the protein kinase regulated by RNA (PKR).
Zhang X, Li J, Sejas DP, Rathbun KR, Bagby GC, Pang Q
The Journal of biological chemistry 2004 Oct 15;279(42):43910-9
The Journal of biological chemistry 2004 Oct 15;279(42):43910-9
Fanconi anemia C gene product regulates expression of genes involved in differentiation and inflammation.
Zanier R, Briot D, Dugas du Villard JA, Sarasin A, Rosselli F
Oncogene 2004 Jun 24;23(29):5004-13
Oncogene 2004 Jun 24;23(29):5004-13
Regulation of the Fanconi anemia group C protein through proteolytic modification.
Brodeur I, Goulet I, Tremblay CS, Charbonneau C, Delisle MC, Godin C, Huard C, Khandjian EW, Buchwald M, Lévesque G, Carreau M
The Journal of biological chemistry 2004 Feb 6;279(6):4713-20
The Journal of biological chemistry 2004 Feb 6;279(6):4713-20
The Fanconi anaemia gene FANCC promotes homologous recombination and error-prone DNA repair.
Niedzwiedz W, Mosedale G, Johnson M, Ong CY, Pace P, Patel KJ
Molecular cell 2004 Aug 27;15(4):607-20
Molecular cell 2004 Aug 27;15(4):607-20
Evidence for at least four Fanconi anaemia genes including FACC on chromosome 9.
Strathdee CA, Duncan AM, Buchwald M
Nature genetics 1992 Jun;1(3):196-8
Nature genetics 1992 Jun;1(3):196-8
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