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- References [6]
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- Western blot [1]
- Immunocytochemistry [1]
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- Product number
- 17008-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17008-1-AP, RRID:AB_2238324
- Product name
- RECQL4 antibody
- Antibody type
- Polyclonal
- Description
- RECQL4 antibody (Cat. #17008-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references USP50 suppresses alternative RecQ helicase use and deleterious DNA2 activity during replication.
DNA replication initiation factor RECQ4 possesses a role in antagonizing DNA replication initiation.
UBE2O and USP7 co-regulate RECQL4 ubiquitinylation and homologous recombination-mediated DNA repair.
The deubiquitinase USP28 stabilizes the expression of RecQ family helicases and maintains the viability of triple negative breast cancer cells.
RECQL4 regulates DNA damage response and redox homeostasis in esophageal cancer.
PARP1 regulates DNA damage-induced nucleolar-nucleoplasmic shuttling of WRN and XRCC1 in a toxicant and protein-specific manner.
Mackay HL, Stone HR, Ellis K, Ronson GE, Walker AK, Starowicz K, Garvin AJ, van Eijk P, Vaitsiankova A, Vijayendran S, Beesley JF, Petermann E, Brown EJ, Densham RM, Reed SH, Dobbs F, Saponaro M, Morris JR
bioRxiv : the preprint server for biology 2024 Jan 11;
bioRxiv : the preprint server for biology 2024 Jan 11;
DNA replication initiation factor RECQ4 possesses a role in antagonizing DNA replication initiation.
Xu X, Chang CW, Li M, Omabe K, Le N, Chen YH, Liang F, Liu Y
Nature communications 2023 Mar 4;14(1):1233
Nature communications 2023 Mar 4;14(1):1233
UBE2O and USP7 co-regulate RECQL4 ubiquitinylation and homologous recombination-mediated DNA repair.
Huang Q, Qin D, Pei D, Vermeulen M, Zhang X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jan;36(1):e22112
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jan;36(1):e22112
The deubiquitinase USP28 stabilizes the expression of RecQ family helicases and maintains the viability of triple negative breast cancer cells.
Wang J, Dong Y, Ma H, Wu L, Zhen X, Tang L, Jin J, Han S, Zhang P, Peng J
The Journal of biological chemistry 2022 Jan;298(1):101443
The Journal of biological chemistry 2022 Jan;298(1):101443
RECQL4 regulates DNA damage response and redox homeostasis in esophageal cancer.
Lyu G, Su P, Hao X, Chen S, Ren S, Zhao Z, Gong Y, Liu Q, Shao C
Cancer biology & medicine 2021 Feb 15;18(1):120-138
Cancer biology & medicine 2021 Feb 15;18(1):120-138
PARP1 regulates DNA damage-induced nucleolar-nucleoplasmic shuttling of WRN and XRCC1 in a toxicant and protein-specific manner.
Veith S, Schink A, Engbrecht M, Mack M, Rank L, Rossatti P, Hakobyan M, Goly D, Hefele T, Frensch M, Fischbach A, Bürkle A, Mangerich A
Scientific reports 2019 Jul 11;9(1):10075
Scientific reports 2019 Jul 11;9(1):10075
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 17008-1-AP(RECQL4 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using RECQL4 antibody 17008-1-AP at 1:100 dilution and FITC-labeled donkey anti-rabbit IgG(green). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
