23302-1-AP

antibody from Proteintech Group

Targeting: ANGPT1 Ang1, KIAA0003

Western blot (Supportive data in Antibodypedia)

ELISA (Data presented on provider website)

Immunocytochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

23302-1-AP

Provider

Proteintech Group

Product name

Angiopoietin 1 antibody

Antibody type

Polyclonal

Description

KD/KO validated Angiopoietin 1 antibody (Cat. #23302-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, WB,ELISA.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

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Mechanism of the Traditional Chinese Medicine Simiao Biejia Decoction Improves the Diabetes Mellitus-Induced Erectile Dysfunction in Rats.

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Drug design, development and therapy 2025;19:2609-2628

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Baicalein ameliorates cognitive decline induced by chronic cerebral hypoperfusion through the SIRT1-mediated Notch1 pathway to improve angiogenesis and suppress neuroinflammation.

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SVF Cell Sheets as a New Multicellular Material-Based Strategy for Promoting Angiogenesis and Regeneration in Diced Cartilage Grafts.

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The Journal of craniofacial surgery 2025 Sep 1;36(6):1889-1898

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Exercise Training Promotes Neural Remodeling and Vascular Regeneration in Cerebral Ischemic Rats Through the JNK/c-jun Signaling Pathway.

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Molecular neurobiology 2025 Oct;62(10):13103-13118

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The relationship between high serum UA levels and decidualization and angiogenesis in endometrium.

Li J, He M, Huang M, Xiang J, Zhang L, Liu Y, Ma Y, Zeng X, Sun X
Scientific reports 2025 Nov 4;15(1):38574

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CD71-Mediated Effects of Soluble Vasorin on Tumor Progression, Angiogenesis and Immunosuppression.

Zhao Y, Xiao C, Li S, Huang A, Li H, Dong J, Qu Q, Liu X, Gao B, Shao N
International journal of molecular sciences 2025 May 20;26(10)

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Angiopoietin-TIE2 feedforward circuit promotes PIK3CA-driven venous malformations.

Kraft M, Schoofs H, Petkova M, Andrade J, Grosso AR, Benedito R, De Roo AK, Boon LM, Vikkula M, Kapp FG, Hägerling R, Potente M, Mäkinen T
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Angiogenesis promotion of the transplantation of human amniotic mesenchymal stem cells via the Ang-1/Tie-2 signaling pathways in Alzheimer's disease model.

Wu R, Guo J, Liu Y, Huang S, Wu P, Liu W
Journal of Alzheimer's disease : JAD 2025 Jul;106(2):646-652

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Beclin1-mediated vascular autophagy negatively regulates angiogenesis and secondary neural damage in the thalamus following cerebral cortical infarction.

Liu M, Chen Y, Fan X, Gu J, Xing S
IBRO neuroscience reports 2025 Dec;19:290-299

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Promotion of mature angiogenesis in ischemic stroke by Taohong Siwu decoction through glycolysis activation.

Tang L, Liu Z, Ji Z, Zhang X, Zhao M, Peng D, Han L
Frontiers in pharmacology 2024;15:1395167

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Chemotactic recruitment of genetically engineered cell membrane-camouflaged metal-organic framework nanoparticles for ischemic osteonecrosis treatment.

Jiang H, Xia W, Xia T, Jiang L, Yu J, Zhu X, Lin C, Lou C, Wang W, Chai Y, Wan R, Wang J, Xue X, Pan X
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Wang Q, Kohls W, Wills M, Li F, Pang Q, Geng X, Ding Y
CNS neuroscience & therapeutics 2024 Jan;30(1):e14405

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Morroniside-mediated mitigation of stem cell and endothelial cell dysfunction for the therapy of glucocorticoid-induced osteonecrosis of the femoral head.

Jiang H, Wang W, Mao Y, Jiang L, Yu J, Zhu X, Fu H, Lin Z, Shen H, Pan X, Xue X
International immunopharmacology 2024 Jan 25;127:111421

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Transplantation of Human Amniotic Mesenchymal Stem Cells Up-Regulates Angiogenic Factor Expression to Attenuate Diabetic Kidney Disease in Rats.

Ni Y, Chen Y, Jiang X, Pu T, Zhang L, Li S, Hu L, Bai B, Hu T, Yu L, Yang Y
Diabetes, metabolic syndrome and obesity : targets and therapy 2023;16:331-343

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Angiopoietin-1 promotes triple-negative breast cancer cell proliferation by upregulating carboxypeptidase A4.

Liu X, Liang H, Fang H, Xiao J, Yang C, Zhou Z, Feng J, Chen C
Acta biochimica et biophysica Sinica 2023 May 9;55(9):1487-1495

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Engineered nanovesicles from stromal vascular fraction promote angiogenesis and adipogenesis inside decellularized adipose tissue through encapsulating growth factors.

Tu J, Zeng Y, An R, Sun J, Wen H
Scientific reports 2023 Jan 13;13(1):750

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The promoting effect of modified Dioscorea pills on vascular remodeling in chronic cerebral hypoperfusion via the Ang/Tie signaling pathway.

Kuang G, Shu Z, Zhu C, Li H, Zhang C
Translational neuroscience 2023 Jan 1;14(1):20220302

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A diagnostic biomarker of acid glycoprotein 1 for distinguishing malignant from benign pulmonary lesions.

Chen Y, Zhang Y, Huang A, Gong Y, Wang W, Pan J, Jin Y
The International journal of biological markers 2023 Dec;38(3-4):167-173

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The Key Role of Initiation Timing on Stroke Rehabilitation by Remote Ischemic Conditioning with Exercise (RICE).

Wang Q, Wehbe A, Wills M, Li F, Geng X, Ding Y
Neurological research 2023 Apr;45(4):334-345

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The PDE5 inhibitor, vardenafil, ameliorates progressive pathological changes in a focal segmental glomerulosclerosis mouse model.

Hu SW, Wang YH, Huang JS, Yang YM, Wu CC, Cheng CW
Life sciences 2022 Nov 15;309:120992

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Ceruletide and Alpha-1 Antitrypsin as a Novel Combination Therapy for Ischemic Stroke.

Simats A, Ramiro L, Valls R, de Ramón H, García-Rodríguez P, Orset C, Artigas L, Sardon T, Rosell A, Montaner J
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2022 Mar;19(2):513-527

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High yield engineered nanovesicles from ADSC with enriched miR-21-5p promote angiogenesis in adipose tissue regeneration.

Sun D, Mou S, Chen L, Yang J, Wang R, Zhong A, Wang W, Tong J, Wang Z, Sun J
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Hyperoxia-induced S1P(1) signaling reduced angiogenesis by suppression of TIE-2 leading to experimental bronchopulmonary dysplasia.

Sudhadevi T, Jafri A, Ha AW, Basa P, Thomas JM, Fu P, Wary K, Mehta D, Natarajan V, Harijith A
Cell biochemistry and biophysics 2021 Sep;79(3):561-573

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Si-Wu-Tang facilitates ovarian function through improving ovarian microenvironment and angiogenesis in a mouse model of premature ovarian failure.

Zhou F, Song Y, Liu X, Zhang C, Li F, Hu R, Huang Y, Ma W, Song K, Zhang M
Journal of ethnopharmacology 2021 Nov 15;280:114431

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Macrophages enhance lipopolysaccharide induced apoptosis via Ang1 and NF-κB pathways in human umbilical vein endothelial cells.

Cai GL, Yang ZX, Guo DY, Hu CB, Yan ML, Yan J
Scientific reports 2021 Feb 3;11(1):2918

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Silicon Oxynitrophosphide Nanoscale Coating Enhances Antioxidant Marker-Induced Angiogenesis During in vivo Cranial Bone-Defect Healing.

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JBMR plus 2021 Apr;5(4):e10425

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Forkhead Box Q1 Is Critical to Angiogenesis and Macrophage Recruitment of Colorectal Cancer.

Tang H, Zheng J, Bai X, Yue KL, Liang JH, Li DY, Wang LP, Wang JL, Guo Q
Frontiers in oncology 2020;10:564298

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Tumor-Derived EV-Encapsulated miR-181b-5p Induces Angiogenesis to Foster Tumorigenesis and Metastasis of ESCC.

Wang Y, Lu J, Chen L, Bian H, Hu J, Li D, Xia C, Xu H
Molecular therapy. Nucleic acids 2020 Jun 5;20:421-437

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MicroRNA‑21 contributes to renal cell carcinoma cell invasiveness and angiogenesis via the PDCD4/c‑Jun (AP‑1) signalling pathway.

Fan B, Jin Y, Zhang H, Zhao R, Sun M, Sun M, Yuan X, Wang W, Wang X, Chen Z, Liu W, Yu N, Wang Q, Liu T, Li X
International journal of oncology 2020 Jan;56(1):178-192

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IGFBP-4 enhances VEGF-induced angiogenesis in a mouse model of myocardial infarction.

Wo D, Chen J, Li Q, Ma E, Yan H, Peng J, Zhu W, Fang Y, Ren DN
Journal of cellular and molecular medicine 2020 Aug;24(16):9466-9471

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Sinomenine mitigates collagen-induced arthritis mice by inhibiting angiogenesis.

Feng ZT, Yang T, Hou XQ, Wu HY, Feng JT, Ou BJ, Cai SJ, Li J, Mei ZG
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 May;113:108759

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Dl-3-N-butylphthalide promotes angiogenesis and upregulates sonic hedgehog expression after cerebral ischemia in rats.

Zhou PT, Wang LP, Qu MJ, Shen H, Zheng HR, Deng LD, Ma YY, Wang YY, Wang YT, Tang YH, Tian HL, Zhang ZJ, Yang GY
CNS neuroscience & therapeutics 2019 Jun;25(6):748-758

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Neuregulin-1 Promotes Myocardial Angiogenesis in the Rat Model of Diabetic Cardiomyopathy.

Gui C, Zeng ZY, Chen Q, Luo YW, Li L, Chen LL
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;46(6):2325-2334

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MicroRNA-9 modified bone marrow-derived mesenchymal stem cells (BMSCs) repair severe acute pancreatitis (SAP) via inducing angiogenesis in rats.

Qian D, Song G, Ma Z, Wang G, Jin L, Hu M, Song Z, Wang X
Stem cell research & therapy 2018 Oct 25;9(1):282

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miR-153 inhibits the migration and the tube formation of endothelial cells by blocking the paracrine of angiopoietin 1 in breast cancer cells.

Liang H, Ge F, Xu Y, Xiao J, Zhou Z, Liu R, Chen C
Angiogenesis 2018 Nov;21(4):849-860

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Repulsive guidance molecule a suppresses angiogenesis after ischemia/reperfusion injury of middle cerebral artery occlusion in rats.

Wang Y, Zhang R, Xing X, Guo J, Xie F, Zhang G, Qin X
Neuroscience letters 2018 Jan 1;662:318-323

---

Canonical hedgehog signalling regulates hepatic stellate cell-mediated angiogenesis in liver fibrosis.

Zhang F, Hao M, Jin H, Yao Z, Lian N, Wu L, Shao J, Chen A, Zheng S
British journal of pharmacology 2017 Mar;174(5):409-423

Western blot

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

mouse heart tissue were subjected to SDS PAGE followed by western blot with 23302-1-AP(ANGPT1 antibody) at dilution of 1:1000

Sample type

tissue

Immunocytochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

The Angiopoietin 1 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human Angiopoietin 1. This antibody recognizes human, mouse, rat antigen. The Angiopoietin 1 antibody has been validated for the following applications: ELISA, WB, IF analysis.

Appendix

23302-1-AP.pdf

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