10676-1-AP

antibody from Proteintech Group

Targeting: FABP3 FABP11, H-FABP, MDGI, O-FABP

Provider product page for 10676-1-AP

Western blot

ELISA

Immunocytochemistry

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [34]
Comments [0]
Validations
Western blot [1]
Immunohistochemistry [2]

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Product number: 10676-1-AP - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#10676-1-AP, RRID:AB_2102309
Product name: FABP3 antibody
Antibody type: Polyclonal
Description: KD/KO validated FABP3 antibody (Cat. #10676-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

FABP3 protein structure - 10676-1-AP shown in red.

Submitted references Pak4-mediated crosstalk between necroptotic macrophages and tendon stem/progenitor cells contributes to traumatic heterotopic ossification formation.

Sun Z, Liu H, Xu Y, Chen Q, Luo G, Yuan Z, Chen Z, He K, Fan C, Li J, Ruan H
Bone research 2025 Oct 20;13(1):88

FABP3 Mediates Lipid Droplet Accumulation and Adhesive Capacity in Bovine Endometrial Epithelial Cells via PGE(2)/PTGER4/PPAR Axis.

Zhang B, Yan Y, Cheng M, Guo T, Gao K, Wang A, Lin P, Zhou D, Jin Y
Animals : an open access journal from MDPI 2025 Nov 26;15(23)

Oleanolic Acid Restores Drug Sensitivity in Sorafenib-resistant Hepatocellular Carcinoma: Evidence from In Vitro and In Vivo Studies.

Li T, Shen X, Zhang T, Ren J, Wang W, Wang D, Zhang P
Journal of clinical and translational hepatology 2025 Jun 28;13(6):469-483

A nine-gene signature with potential targets for predicting the prognosis of patients with esophageal cancer.

Sun M, Ma Y, Zhou F, Xiang Q, He S, Yu J, Wang W, Qi J, Wang Y, Sun Q, Li H, Chen Y, Cui X
Translational cancer research 2025 Jul 30;14(7):4305-4320

ALKBH5 regulates intrauterine adhesion progression through m6A dependent FABP4 mRNA stabilization and serum lipid metabolism.

Yang X, Feng Q
Communications biology 2025 Jul 1;8(1):973

Effects of resveratrol on growth performance, meat quality, and intramuscular fat deposition in finishing steers.

Yang M, Ji K, Liu X, Wang Z, Lin X, Zhao H, Zhang X
Journal of animal science 2025 Jan 4;103

Luminal hormone-responsive cells tune the regenerative remodeling of mammary glands in large mammals.

Li Y, Zhang L, Luo T, Zhang W, Wang T, Liu F, Lin S, Luo J, Liu J, Peng J, Wang C, Wang W, Shi H
Cell discovery 2025 Dec 30;11(1):105

Profile of miRNAs induced during sheep fat tail development and roles of four key miRNAs in proliferation and differentiation of sheep preadipocytes.

Zhang W, Wang S, Yang L, Gao L, Ning C, Xu M, Deng S, Gan S
Frontiers in veterinary science 2024;11:1491160

An integrated multi-omics analysis reveals osteokines involved in global regulation.

Liang W, Wei T, Hu L, Chen M, Tong L, Zhou W, Duan X, Zhao X, Zhou W, Jiang Q, Xiao G, Zou W, Chen D, Zou Z, Bai X
Cell metabolism 2024 May 7;36(5):1144-1163.e7

Extracellular vesicle mediated targeting delivery of growth differentiation factor-15 improves myocardial repair by reprogramming macrophages post myocardial injury.

Xiao T, Wei J, Cai D, Wang Y, Cui Z, Chen Q, Gu Q, Zou A, Mao L, Chi B, Ji Y, Wang Q, Sun L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Mar;172:116224

Autophagy regulates age-related delayed jawbone regeneration and decreased osteoblast osteogenesis by degrading FABP3.

Xu Y, Sun B, Wang H, Cai Y, Chu D, Cao R, Wang Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jul 31;38(14):e23824

FABP3 Induces Mitochondrial Autophagy to Promote Neuronal Cell Apoptosis in Brain Ischemia-Reperfusion Injury.

Zhong FF, Wei B, Bao GX, Lou YP, Wei ME, Wang XY, Xiao X, Tian JJ
Neurotoxicity research 2024 Jul 15;42(4):35

The oxidized phospholipid PGPC impairs endothelial function by promoting endothelial cell ferroptosis via FABP3.

Chen S, Gao JJ, Liu YJ, Mo ZW, Wu FY, Hu ZJ, Peng YM, Zhang XQ, Ma ZS, Liu ZL, Yan JY, Ou ZJ, Li Y, Ou JS
Journal of lipid research 2024 Feb;65(2):100499

GFPT1 accelerates immune escape in breast cancer by modifying PD-L1 via O-glycosylation.

Tang W, Gao Y, Hong S, Wang S
BMC cancer 2024 Aug 29;24(1):1071

Novel FABP3 ligand, HY-11-9, ameliorates neuropathological deficits in MPTP-induced Parkinsonism in mice.

Wang H, Fukunaga K, Cheng A, Wang Y, Arimura N, Yoshino H, Sasaki T, Kawahata I
Journal of pharmacological sciences 2023 May;152(1):30-38

α-Synuclein decoy peptide protects mice against α-synuclein-induced memory loss.

Guo Q, Kawahata I, Jia W, Wang H, Cheng A, Yabuki Y, Shioda N, Fukunaga K
CNS neuroscience & therapeutics 2023 Jun;29(6):1547-1560

Nanointegrative In Situ Reprogramming of Tumor-Intrinsic Lipid Droplet Biogenesis for Low-Dose Radiation-Activated Ferroptosis Immunotherapy.

Zhang Q, Wang X, Zhao Y, Cheng Z, Fang D, Liu Y, Tian G, Li M, Luo Z
ACS nano 2023 Dec 26;17(24):25419-25438

Decreased Imiquimod-Induced Psoriasis-Like Skin Inflammation in a Novel Mvd(F250S/+) Knock-In Mouse Model.

La Y, Wong W, Peng K, Tian Z, Pan J, Sun R, Luan J, Yan K, Zhang Q, Zhang Z
Inflammation 2023 Aug;46(4):1575-1586

Amelioration of Nicotine-Induced Conditioned Place Preference Behaviors in Mice by an FABP3 Inhibitor.

Jia W, Kawahata I, Cheng A, Sasaki T, Sasaoka T, Fukunaga K
International journal of molecular sciences 2023 Apr 2;24(7)

Single-cell analysis of embryoids reveals lineage diversification roadmaps of early human development.

Zheng Y, Yan RZ, Sun S, Kobayashi M, Xiang L, Yang R, Goedel A, Kang Y, Xue X, Esfahani SN, Liu Y, Resto Irizarry AM, Wu W, Li Y, Ji W, Niu Y, Chien KR, Li T, Shioda T, Fu J
Cell stem cell 2022 Sep 1;29(9):1402-1419.e8

Fatty acid metabolism is involved in both retinal physiology and the pathology of retinal vascular diseases.

Umetsu A, Furuhashi M, Watanabe M, Ohkawa E, Tsugeno Y, Suzuki S, Itoh K, Ida Y, Hikage F, Ohguro H
Prostaglandins, leukotrienes, and essential fatty acids 2022 Aug;183:102473

Quantitative Ubiquitylome Analysis Reveals the Specificity of RNF111/Arkadia E3 Ubiquitin Ligase for its Degradative Substrates SKI and SKIL/SnoN in TGF-β Signaling Pathway.

Laigle V, Dingli F, Amhaz S, Perron T, Chouchène M, Colasse S, Petit I, Poullet P, Loew D, Prunier C, Levy L
Molecular & cellular proteomics : MCP 2021;20:100173

Fatty Acid-Binding Protein 3 Expression in the Brain and Skin in Human Synucleinopathies.

Oizumi H, Yamasaki K, Suzuki H, Hasegawa T, Sugimura Y, Baba T, Fukunaga K, Takeda A
Frontiers in aging neuroscience 2021;13:648982

Exploring the Multi-Tissue Crosstalk Relevant to Insulin Resistance Through Network-Based Analysis.

Yang L, Yang L, Wang X, Xing H, Zhao H, Xing Y, Zhou F, Wang C, Song G, Ma H
Frontiers in endocrinology 2021;12:756785

MMP-12 siRNA improves the homeostasis of the small intestine and metabolic dysfunction in high-fat diet feeding-induced obese mice.

Song M, Zhang S, Tao Z, Li J, Shi Y, Xiong Y, Zhang W, Liu C, Chen S
Biomaterials 2021 Nov;278:121183

Stomach secretes estrogen in response to the blood triglyceride levels.

Ito T, Yamamoto Y, Yamagishi N, Kanai Y
Communications biology 2021 Dec 7;4(1):1364

Prohibitin 2 deficiency impairs cardiac fatty acid oxidation and causes heart failure.

Wu D, Jian C, Peng Q, Hou T, Wu K, Shang B, Zhao M, Wang Y, Zheng W, Ma Q, Li CY, Cheng H, Wang X, Zhao L
Cell death & disease 2020 Mar 12;11(3):181

Development of FABP3 ligands that inhibit arachidonic acid-induced α-synuclein oligomerization.

Cheng A, Shinoda Y, Yamamoto T, Miyachi H, Fukunaga K
Brain research 2019 Mar 15;1707:190-197

Downregulations of placental fatty acid transporters during cadmium-induced fetal growth restriction.

Xu P, Guo H, Wang H, Lee SC, Liu M, Pan Y, Zheng J, Zheng K, Wang H, Xie Y, Bai X, Liu Y, Zhao M, Wang L
Toxicology 2019 Jul 1;423:112-122

Aberrant fatty acid metabolism in skeletal muscle contributes to insulin resistance in zinc transporter 7 (znt7)-knockout mice.

Huang L, Tepaamorndech S, Kirschke CP, Newman JW, Keyes WR, Pedersen TL, Dumnil J
The Journal of biological chemistry 2018 May 18;293(20):7549-7563

FABP3 in the Anterior Cingulate Cortex Modulates the Methylation Status of the Glutamic Acid Decarboxylase(67) Promoter Region.

Yamamoto Y, Kida H, Kagawa Y, Yasumoto Y, Miyazaki H, Islam A, Ogata M, Yanagawa Y, Mitsushima D, Fukunaga K, Owada Y
The Journal of neuroscience : the official journal of the Society for Neuroscience 2018 Dec 5;38(49):10411-10423

Malathion increases apoptotic cell death by inducing lysosomal membrane permeabilization in N2a neuroblastoma cells: a model for neurodegeneration in Alzheimer's disease.

Venkatesan R, Park YU, Ji E, Yeo EJ, Kim SY
Cell death discovery 2017;3:17007

FABP3 protein promotes α-synuclein oligomerization associated with 1-methyl-1,2,3,6-tetrahydropiridine-induced neurotoxicity.

Shioda N, Yabuki Y, Kobayashi Y, Onozato M, Owada Y, Fukunaga K
The Journal of biological chemistry 2014 Jul 4;289(27):18957-65

Identification of protein targets underlying dietary nitrate-induced protection against doxorubicin cardiotoxicity.

Xi L, Zhu SG, Hobbs DC, Kukreja RC
Journal of cellular and molecular medicine 2011 Nov;15(11):2512-24

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: mouse heart tissue were subjected to SDS PAGE followed by western blot with 10676-1-AP(FABP3 antibody) at dilution of 1:1000
Sample type: tissue

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: The FABP3 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human FABP3. This antibody recognizes human,mouse,rat antigen. The FABP3 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
Appendix: 10676-1-AP.pdf

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: Immunohistochemical of paraffin-embedded human breast cancer using 10676-1-AP(FABP3 antibody) at dilution of 1:50 (under 40x lens)
Sample type: tissue