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Learn13147-1-AP
antibody from Proteintech Group
Targeting: FOXM1
FKHL16, HFH-11, HNF-3, INS-1, MPHOSPH2, MPP2, TGT3, trident
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ELISAAntibody data
- Antibody Data
- Antigen structure
- References [124]
- Comments [0]
- Validations
- Western blot [1]
- Immunoprecipitation [1]
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- Product number
- 13147-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13147-1-AP, RRID:AB_2106213
- Product name
- FOXM1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated FOXM1 antibody (Cat. #13147-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references NEDD4 promotes reactive astrogliosis by enhancing K63-linked ubiquitination and inhibiting chaperone-mediated autophagy degradation of YAP1.
Design, Synthesis, Biological Evaluation, and Molecular Modeling Studies of Novel 2-Aminothiazole Derivatives as Potential FOXM1 Inhibitors for Triple-Negative Breast Cancer Therapy and Structure-Activity Relationship.
A novel recombinant peptide, rAnguillin, induces ferroptosis in nasopharyngeal carcinoma by promoting FOXM1 degradation and disrupting the FOXM1-PABPC1L-tryptophan metabolism axis.
VGLL3 Regulates DAPK2-Mediated Autophagy During Osteoblast Differentiation.
Adiponectin Inhibits AURKA to Suppress Inflammation in TNF-α-induced Keratinocytes and Attenuates Psoriatic Dermatitis in Mice.
STUB1 downregulates TOP2A through a dual mechanism of ubiquitination and FOXM1-mediated transcription repression, suppressing breast cancer growth and enhancing sensitivity to chemotherapy.
Lipid-Driven OLR1/FOXM1/FGF19 Axis Orchestrates Crosstalk in an Epithelial-Fibroblast Positive Feedback Promoting Progesterone Resistance in Endometrial Cancer.
Mitochondria-located circRCP regulates redox homeostasis via stabilizing LRPPRC/SLIRP complex to promote bladder urothelial carcinoma tumorigenesis.
Transcriptomic landscape of transposable elements reveals LTR7-PLAAT4 as a potential oncogene and therapeutic target in pancreatic adenocarcinoma.
DNA Methylation-Regulated FAM107A Affects Colorectal Carcinogenesis by Inhibiting FOXM1.
OSBPL3 promotes LUAD metastasis and glycolysis through transcriptional upregulation of PLAU via NFE2L2.
Erianin facilitates pyroptosis in endometrial cancer via targeting m6A reader YTHDF1.
Copper-Based Metal-Organic Framework Nanoplatform for miRNA Delivery: Synergistic Antitumor Therapy.
Lasalocid inhibits melanoma by down-regulating FOXM1 through PI3K/AKT and JNK/P38 MAPK pathways.
Discovery of Baicalein as a Novel Ubiquitin-Specific Protease 21 Inhibitor for the Treatment of Hepatocellular Carcinoma.
ALKBH5 reverses romidepsin-mediated anti-multiple myeloma activity via regulation of m6A modification of FOXM1.
Identification and characterization of a potent peptide inhibitor targeting FOXM1 in cancer therapy.
Mouse mesenchymal stem cell-derived exosomal miR-205-5p modulates LPS-induced macrophage polarization and alleviates lung injury by regulating the USP7/FOXM1 axis.
Wnt/ERK/CDK4/6 activation in the partial EMT state coordinates mammary cancer stemness with self-renewal and inhibition of differentiation.
Transcriptomic Investigation of FoxM1-Mediated Neuroprotection by hAEC-Derived Exosomes in an In Vitro Ischemic Stroke Model.
Activating NEDD4L suppresses EGFR-driven lung adenocarcinoma growth via facilitating EGFR proteasomal degradation.
The secreted metabolite sensor CtBP2 links metabolism to healthy lifespan.
Adolescent cetylpyridinium chloride exposure impairs homologous recombination repair and induces granulosa cell apoptosis and follicular atresia via FOXM1/CREBBP complex suppression.
FOXM1 expression reverts aging chromatin profiles through repression of the senescence-associated pioneer factor AP-1.
Adult Hymenolepis nana and its excretory-secretory products elicit mouse immune responses via tuft/IL-13 and FOXM1 signaling pathways.
New mechanism of miR-34a-5p in regulating the biological behavior of osteosarcoma by targeting FoxM1.
Deuterium-depleted water inhibits the malignant progression of colorectal cancer cells by modulating oxidative stress.
Short-term consumption of the modified standard American diet perturbed the metabolic balance and altered DNA damage in MMTV-PyMT transgenic mice.
Smoking promotes the progression of bladder cancer through FOXM1/CKAP2L axis.
RO4929097 inhibits NICD3 to alleviate pulmonary hypertension via blocking Notch3/HIF-2α/FoxM1 signaling pathway.
N6-methyladenosine-modified circRPS6KC1 regulated cellular senescence in prostate cancer via FOXM1/PCNA axis.
NEK2 Promotes ESCC Malignant Progression by Inhibiting Cellular Senescence via the FOXM1/c-Myc/p27 Signaling Pathway.
Organophosphate flame retardant triphenyl phosphate (TPhP) induced colonic fibrosis by bringing about epithelial-mesenchymal transition.
Enhanced or reversible RNA N6-methyladenosine editing by red/far-red light induction.
m6A reader IGF2BP2 mediates paclitaxel resistance in esophageal squamous cell carcinoma via FOXM1 mRNA stabilization.
Abrogation of aberrant glycolytic interactions eliminates senescent cells and alleviates aging-related dysfunctions.
TRIM47 Facilitates Osteosarcoma Progression via Destabilising FBP1 and Thus Activation of Wnt/β-Catenin Pathway.
Exploring the Molecular Mechanism of 1,25(OH)(2)D(3) Reversal of Sorafenib Resistance in Hepatocellular Carcinoma Based on Network Pharmacology and Experimental Validation.
Down-regulation of microRNA-23a promotes pancreatic ductal adenocarcinoma initiation and progression by up-regulation of FOXM1 expression.
Vascular restenosis following paclitaxel-coated balloon therapy is attributable to NLRP3 activation and LIN9 upregulation.
The role of forkhead box M1-methionine adenosyltransferase 2 A/2B axis in liver inflammation and fibrosis.
Dibenzolium induces apoptosis and inhibits epithelial-mesenchymal transition (EMT) in bladder cancer cell lines.
CPT1A mediates radiation sensitivity in colorectal cancer.
Activation of the FOXM1/ASF1B/PRDX3 axis confers hyperproliferative and antioxidative stress reactivity to gastric cancer.
OTUD7B knockdown inhibits the proliferation and stemness of breast cancer cells by destabilizing FOXM1.
Protective effect of Cyclo(His-Pro) on peritoneal fibrosis through regulation of HDAC3 expression.
Huaier enhances the tumor-killing effect and reverses gemcitabine-induced stemness by suppressing FoxM1.
A role for YAP/FOXM1/Nrf2 axis in oxidative stress and apoptosis of cataract induced by UVB irradiation.
AKT/FOXM1/STMN1 signaling pathway activation by SMC1A promotes tumor growth in breast cancer.
Targeting FBXO22 enhances radiosensitivity in non-small cell lung cancer by inhibiting the FOXM1/Rad51 axis.
FOXM1 promote the growth and metastasis of uveal melanoma cells by regulating CDK2 expression.
Novel benzothiazole/benzothiazole thiazolidine-2,4-dione derivatives as potential FOXM1 inhibitors: In silico, synthesis, and in vitro studies.
SNRPB2 promotes triple-negative breast cancer progression by controlling alternative splicing of MDM4 pre-mRNA.
FOXM1 c.1205 C > A mutation is associated with unilateral Moyamoya disease and inhibits angiogenesis in human brain endothelial cells.
GAPDH: A common housekeeping gene with an oncogenic role in pan-cancer.
Ly6D facilitates chemoresistance in laryngeal squamous cell carcinoma through miR-509/β-catenin signaling pathway.
High-risk histological subtype-related FAM83A hijacked FOXM1 transcriptional regulation to promote malignant progression in lung adenocarcinoma.
Increased α-HB links colorectal cancer and diabetes by potentiating NF-κB signaling.
A patient-derived organoid-based study identified an ASO targeting SNORD14E for endometrial cancer through reducing aberrant FOXM1 Expression and β-catenin nuclear accumulation.
Activation of LXRα attenuates 2-Ethylhexyl diphenyl phosphate (EHDPP) induced placental dysfunction.
K235 acetylation couples with PSPC1 to regulate the m(6)A demethylation activity of ALKBH5 and tumorigenesis.
MRPL51 is a downstream target of FOXM1 in promoting the malignant behaviors of lung adenocarcinoma.
Comprehensive bioinformatics analysis reveals the significance of forkhead box family members in pancreatic adenocarcinoma.
ERCC6L facilitates the progression of laryngeal squamous cell carcinoma by the binding of FOXM1 and KIF4A.
Overexpression of FoxM1 optimizes the therapeutic effect of bone marrow mesenchymal stem cells on acute respiratory distress syndrome.
Keratin 17 Impacts Global Gene Expression and Controls G2/M Cell Cycle Transition in Ionizing Radiation-Induced Skin Damage.
Interactions between BRD4S, LOXL2, and MED1 drive cell cycle transcription in triple-negative breast cancer.
Hepatic vagotomy blunts liver regeneration after hepatectomy by downregulating the expression of interleukin-22.
HNRNPA2B1-mediated m6A modification of FOXM1 promotes drug resistance and inhibits ferroptosis in endometrial cancer via regulation of LCN2.
RNA-binding protein CCDC137 activates AKT signaling and promotes hepatocellular carcinoma through a novel non-canonical role of DGCR8 in mRNA localization.
In silico, in vitro and in vivo studies: Dibutyl phthalate promotes prostate cancer cell proliferation by activating Forkhead Box M1 and remission after Natura-α pretreatment.
Coordinated activation of c-Src and FOXM1 drives tumor cell proliferation and breast cancer progression.
Knockdown MTDH Inhibits Glioma Proliferation and Migration and Promotes Apoptosis by Downregulating MYBL2.
Characterizing and Targeting Genes Regulated by Transcription Factor MYBL2 in Lung Adenocarcinoma Cells.
In vivo cyclic induction of the FOXM1 transcription factor delays natural and progeroid aging phenotypes and extends healthspan.
Induction of cancer cell stemness in glioma through glycolysis and the long noncoding RNA HULC-activated FOXM1/AGR2/HIF-1α axis.
IFNα Potentiates Anti-PD-1 Efficacy by Remodeling Glucose Metabolism in the Hepatocellular Carcinoma Microenvironment.
The human FOXM1 homolog promotes basal progenitor cell proliferation and cortical folding in mouse.
A novel combination treatment of antiADAM17 antibody and erlotinib to overcome acquired drug resistance in non-small cell lung cancer through the FOXO3a/FOXM1 axis.
Long noncoding RNA SH3PXD2A-AS1 promotes NSCLC proliferation and accelerates cell cycle progression by interacting with DHX9.
Comprehensive Analysis Uncovers Prognostic and Immunogenic Characteristics of Cellular Senescence for Lung Adenocarcinoma.
Development of a novel gene signature to predict prognosis and response to PD-1 blockade in clear cell renal cell carcinoma.
Paired-like homeodomain transcription factor 2 affects endometrial cell function and embryo implantation through the Wnt/β-catenin pathway.
The FOXM1/RNF26/p57 axis regulates the cell cycle to promote the aggressiveness of bladder cancer.
NOX4-derived ROS-induced overexpression of FOXM1 regulates aerobic glycolysis in glioblastoma.
FOXM1-activated SIRT4 inhibits NF-κB signaling and NLRP3 inflammasome to alleviate kidney injury and podocyte pyroptosis in diabetic nephropathy.
HMMR is a downstream target of FOXM1 in enhancing proliferation and partial epithelial-to-mesenchymal transition of bladder cancer cells.
Constitutive androstane receptor induced-hepatomegaly and liver regeneration is partially via yes-associated protein activation.
Fork head box M1 regulates vascular endothelial growth factor-A expression to promote the angiogenesis and tumor cell growth of gallbladder cancer.
Hsa_circ_0042823 accelerates cancer progression via miR-877-5p/FOXM1 axis in laryngeal squamous cell carcinoma.
LRPPRC regulates redox homeostasis via the circANKHD1/FOXM1 axis to enhance bladder urothelial carcinoma tumorigenesis.
Schisandrol B promotes liver enlargement via activation of PXR and YAP pathways in mice.
miR-877-5p Suppresses Gastric Cancer Cell Proliferation Through Targeting FOXM1.
Dexamethasone-Induced Liver Enlargement Is Related to PXR/YAP Activation and Lipid Accumulation but Not Hepatocyte Proliferation.
The differences of regulatory networks between papillary and anaplastic thyroid carcinoma: an integrative transcriptomics study.
FoxM1 promotes the migration of ovarian cancer cell through KRT5 and KRT7.
miR-877-5p antagonizes the promoting effect of SP on the gastric cancer progression.
LncRNA MFI2-AS1 promotes HCC progression and metastasis by acting as a competing endogenous RNA of miR-134 to upregulate FOXM1 expression.
A Cdh1-FoxM1-Apc axis controls muscle development and regeneration.
circFOXM1 promotes proliferation of non-small cell lung carcinoma cells by acting as a ceRNA to upregulate FAM83D.
MiR-346-5p promotes colorectal cancer cell proliferation in vitro and in vivo by targeting FBXL2 and activating the β-catenin signaling pathway.
UCHL3 promotes pancreatic cancer progression and chemo-resistance through FOXM1 stabilization.
Integrated Bioinformatics Analysis of Master Regulators in Anaplastic Thyroid Carcinoma.
Promotion of liver growth by CAR is accompanied by Akt pathway activation and FoxM1-Nedd4-mediated repression of PTEN.
circTP63 functions as a ceRNA to promote lung squamous cell carcinoma progression by upregulating FOXM1.
Suppression of Hepatocellular Carcinoma Progression through FOXM1 and EMT Inhibition via Hydroxygenkwanin-Induced miR-320a Expression.
Dynamically decreased miR-671-5p expression is associated with oncogenic transformation and radiochemoresistance in breast cancer.
PARI functions as a new transcriptional target of FOXM1 involved in gastric cancer development.
Expression and functional characterization of FOXM1 in non-small cell lung cancer.
3-O-acetyl-11-keto-β-boswellic acid exerts anti-tumor effects in glioblastoma by arresting cell cycle at G2/M phase.
FoxM1 repression during human aging leads to mitotic decline and aneuploidy-driven full senescence.
Vagus-macrophage-hepatocyte link promotes post-injury liver regeneration and whole-body survival through hepatic FoxM1 activation.
Minute Virus of Mice Inhibits Transcription of the Cyclin B1 Gene during Infection.
FOXM1 regulates glycolysis in hepatocellular carcinoma by transactivating glucose transporter 1 expression.
Association between FOXM1 and hedgehog signaling pathway in human cervical carcinoma by tissue microarray analysis.
Microarray-based gene expression profiling reveals genes and pathways involved in the oncogenic function of REG3A on pancreatic cancer cells.
miR-671-5p inhibits epithelial-to-mesenchymal transition by downregulating FOXM1 expression in breast cancer.
LncBRM initiates YAP1 signalling activation to drive self-renewal of liver cancer stem cells.
POH1 deubiquitylates and stabilizes E2F1 to promote tumour formation.
Silibinin-induced glioma cell apoptosis by PI3K-mediated but Akt-independent downregulation of FoxM1 expression.
Protective effects of calycosin against CCl4-induced liver injury with activation of FXR and STAT3 in mice.
Overexpression of FOXM1 predicts poor prognosis and promotes cancer cell proliferation, migration and invasion in epithelial ovarian cancer.
Effects of metformin on FOXM1 expression and on the biological behavior of acute leukemia cell lines.
Expression and significance of FOXM1 in human cervical cancer: a tissue micro-array study.
Ye W, Li Y, Wang W, Pan D, Wang X, Gu Y, Zhu Y, Wang H, Lu X, Jiang D, Tang P, Shu H, Ma J, Cai W
International journal of biological sciences 2026;22(2):858-875
International journal of biological sciences 2026;22(2):858-875
Design, Synthesis, Biological Evaluation, and Molecular Modeling Studies of Novel 2-Aminothiazole Derivatives as Potential FOXM1 Inhibitors for Triple-Negative Breast Cancer Therapy and Structure-Activity Relationship.
Abusharkh KAN, Çınar V, Onder A, Sıkık M, Mustafa Guzel, Hamurcu Z, Ozpolat B, Ay M, Comert Onder F
Drug development research 2026 May;87(3):e70296
Drug development research 2026 May;87(3):e70296
A novel recombinant peptide, rAnguillin, induces ferroptosis in nasopharyngeal carcinoma by promoting FOXM1 degradation and disrupting the FOXM1-PABPC1L-tryptophan metabolism axis.
Yuan Q, Zhao Y, Zhou F, Zhang Y, Jia X, Yao J, Lv M, Wang J, Lv L
International journal of biological macromolecules 2026 May;361:151988
International journal of biological macromolecules 2026 May;361:151988
VGLL3 Regulates DAPK2-Mediated Autophagy During Osteoblast Differentiation.
He Y, Wang Z, Weng Y, Sitosari H, Zheng Y, Qu Y, Ikegame M, Okamura H
BioFactors (Oxford, England) 2026 May-Jun;52(3):e70104
BioFactors (Oxford, England) 2026 May-Jun;52(3):e70104
Adiponectin Inhibits AURKA to Suppress Inflammation in TNF-α-induced Keratinocytes and Attenuates Psoriatic Dermatitis in Mice.
Zhang L, Ke C, Shen Y, Shi F, Jiao Q, Ji J
Immunity, inflammation and disease 2026 Mar;14(3):e70407
Immunity, inflammation and disease 2026 Mar;14(3):e70407
STUB1 downregulates TOP2A through a dual mechanism of ubiquitination and FOXM1-mediated transcription repression, suppressing breast cancer growth and enhancing sensitivity to chemotherapy.
Yue B, Xiang Q, Qiu H, Huang M, Qi M, Yi X, Zhou S, Xiong J
Cellular & molecular biology letters 2026 Mar 18;31(1)
Cellular & molecular biology letters 2026 Mar 18;31(1)
Lipid-Driven OLR1/FOXM1/FGF19 Axis Orchestrates Crosstalk in an Epithelial-Fibroblast Positive Feedback Promoting Progesterone Resistance in Endometrial Cancer.
Li X, Qi Y, Wu Y, Bi X, Wang Y, Wang J, Wang J, Zhang L, Xiao H, Wang J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(6):e11943
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(6):e11943
Mitochondria-located circRCP regulates redox homeostasis via stabilizing LRPPRC/SLIRP complex to promote bladder urothelial carcinoma tumorigenesis.
Zhou ZH, Wen JH, Zhang YZ, Yao K, Li ZY, Li XD, Wang YJ, Jiang LJ, Ye YL, Qin Z, Liu ZW, Zhou FJ, Chen RX, Xie D, Wei WS
Cancer letters 2026 Jan 28;638:218157
Cancer letters 2026 Jan 28;638:218157
Transcriptomic landscape of transposable elements reveals LTR7-PLAAT4 as a potential oncogene and therapeutic target in pancreatic adenocarcinoma.
Shi M, Teng C, Zhang S, He X, Xu L, Han F, Wen R, Yu G, Liu J, Feng Y, Wu Y, Ren Y, Jin G, Li J
Genome research 2026 Feb 3;36(2):275-290
Genome research 2026 Feb 3;36(2):275-290
DNA Methylation-Regulated FAM107A Affects Colorectal Carcinogenesis by Inhibiting FOXM1.
Liu Y, Sun J, Shi Y, Wang L, Zhang X, Chen L
Journal of investigative surgery : the official journal of the Academy of Surgical Research 2026 Dec;39(1):2633933
Journal of investigative surgery : the official journal of the Academy of Surgical Research 2026 Dec;39(1):2633933
OSBPL3 promotes LUAD metastasis and glycolysis through transcriptional upregulation of PLAU via NFE2L2.
Zhang Q, Zhang J, Li J, Chen S, Liu Y, Li K, Guo M
Translational oncology 2026 Apr;66:102693
Translational oncology 2026 Apr;66:102693
Erianin facilitates pyroptosis in endometrial cancer via targeting m6A reader YTHDF1.
Shu W, Zhou X, Zhao R, Dong K, Shen X, Chen G, Cheng S, Zhang Q, Zhou T, Zhang J, Zhang T, Yu S, Li H, Yao Y, Liu Y, Zhang J, Wang H
Chinese medicine 2026 Apr 7;21(1)
Chinese medicine 2026 Apr 7;21(1)
Copper-Based Metal-Organic Framework Nanoplatform for miRNA Delivery: Synergistic Antitumor Therapy.
Tu M, Deng X, Lai B, Liu J, Tao Y, Xu S, Li X, Niu X, Li Z, Huang J, Li J, Mao S, Ouyang X, Cao J
International journal of nanomedicine 2025;20:8675-8692
International journal of nanomedicine 2025;20:8675-8692
Lasalocid inhibits melanoma by down-regulating FOXM1 through PI3K/AKT and JNK/P38 MAPK pathways.
Yuan Q, Jiang H, Zhu M, Chu Y, Zhang Y, Bie J, Li L
Journal of Cancer 2025;16(3):765-783
Journal of Cancer 2025;16(3):765-783
Discovery of Baicalein as a Novel Ubiquitin-Specific Protease 21 Inhibitor for the Treatment of Hepatocellular Carcinoma.
Jia H, Zhao Z, Su C, Du J, Yang S, Song J, Han X, Yu F, Sun Z, Chu P
Phytotherapy research : PTR 2025 Sep;39(9):3935-3951
Phytotherapy research : PTR 2025 Sep;39(9):3935-3951
ALKBH5 reverses romidepsin-mediated anti-multiple myeloma activity via regulation of m6A modification of FOXM1.
Zhang Y, Cao X, Li W, Cui Z, Mao J, Yao R, Liu L
Biochemical pharmacology 2025 Sep;239:116998
Biochemical pharmacology 2025 Sep;239:116998
Identification and characterization of a potent peptide inhibitor targeting FOXM1 in cancer therapy.
Liang A, Chang M, Shang Z, Wang S, Huai R, Hua X, Wu D, Xiang K, Qi S, Jia S, Qi H, Jiang Y, Liu X, Mao C
Biochemical pharmacology 2025 Oct;240:117064
Biochemical pharmacology 2025 Oct;240:117064
Mouse mesenchymal stem cell-derived exosomal miR-205-5p modulates LPS-induced macrophage polarization and alleviates lung injury by regulating the USP7/FOXM1 axis.
Feng Y, Tang M, Li H, Yao S, Li B
Drug delivery and translational research 2025 Oct;15(10):3480-3496
Drug delivery and translational research 2025 Oct;15(10):3480-3496
Wnt/ERK/CDK4/6 activation in the partial EMT state coordinates mammary cancer stemness with self-renewal and inhibition of differentiation.
Liang H, Benard O, Kumar V, Griffen A, Ren Z, Sivalingam K, Wang J, de Simone Benito E, Zhang X, Zhang J, Suyama K, LaFave LM, Norton L, Hazan RB
British journal of cancer 2025 Oct;133(7):986-1002
British journal of cancer 2025 Oct;133(7):986-1002
Transcriptomic Investigation of FoxM1-Mediated Neuroprotection by hAEC-Derived Exosomes in an In Vitro Ischemic Stroke Model.
Wang D, Liu J, Wu L, Yang X, Fang Z, Sun Z, Chen D
Biology 2025 Oct 7;14(10)
Biology 2025 Oct 7;14(10)
Activating NEDD4L suppresses EGFR-driven lung adenocarcinoma growth via facilitating EGFR proteasomal degradation.
Chen M, Jiang W, Zhan J, Zhang S, Zheng J, Huang Y, He J, Yang Y, Zhao S, Zhang Y, Liu J, Pang L, Zhang L, Fang W, Li J
Journal of experimental & clinical cancer research : CR 2025 Oct 21;44(1):294
Journal of experimental & clinical cancer research : CR 2025 Oct 21;44(1):294
The secreted metabolite sensor CtBP2 links metabolism to healthy lifespan.
Sekiya M, Kainoh K, Chen W, Yamazaki D, Tsuyuzaki T, Kobari Y, Nakata A, Saito K, Aono-Soma N, Majid A, Ohno H, Miyamoto T, Matsuzaka T, Nakajima R, Matsuda T, Murayama Y, Sugano Y, Osaki Y, Iwasaki H, Shimano H
Nature aging 2025 Nov;5(11):2197-2214
Nature aging 2025 Nov;5(11):2197-2214
Adolescent cetylpyridinium chloride exposure impairs homologous recombination repair and induces granulosa cell apoptosis and follicular atresia via FOXM1/CREBBP complex suppression.
Ma L, Yin X, Zhang Y, Ma Y, Geng Y, Mu X, Gao R, Chen X, He J
Ecotoxicology and environmental safety 2025 May;296:118193
Ecotoxicology and environmental safety 2025 May;296:118193
FOXM1 expression reverts aging chromatin profiles through repression of the senescence-associated pioneer factor AP-1.
Ferreira FJ, Galhardo M, Nogueira JM, Teixeira J, Logarinho E, Bessa J
Nature communications 2025 Mar 25;16(1):2931
Nature communications 2025 Mar 25;16(1):2931
Adult Hymenolepis nana and its excretory-secretory products elicit mouse immune responses via tuft/IL-13 and FOXM1 signaling pathways.
Mou R, Cui XY, Luo YS, Cheng Y, Luo QY, Zhang ZF, Wu WL, Li JF, Zhang K
Parasites & vectors 2025 Mar 11;18(1):100
Parasites & vectors 2025 Mar 11;18(1):100
New mechanism of miR-34a-5p in regulating the biological behavior of osteosarcoma by targeting FoxM1.
Shen W, Liu X, Wang S, Du S, Cong L, Ma Y, Ye K
Cytotechnology 2025 Jun;77(3):90
Cytotechnology 2025 Jun;77(3):90
Deuterium-depleted water inhibits the malignant progression of colorectal cancer cells by modulating oxidative stress.
Li C, Cheng X, Jiang Y
Oncology reports 2025 Jun;53(6)
Oncology reports 2025 Jun;53(6)
Short-term consumption of the modified standard American diet perturbed the metabolic balance and altered DNA damage in MMTV-PyMT transgenic mice.
Hernandez A, Puppala A, Hedlich-Dwyer J, Mukherjee N, Zhai G, Zotto VLD, Ning B, Guo H, Aneja R, Gassman NR
Breast cancer research : BCR 2025 Jul 25;27(1):138
Breast cancer research : BCR 2025 Jul 25;27(1):138
Smoking promotes the progression of bladder cancer through FOXM1/CKAP2L axis.
Wu F, Wu S, Huang Y, Xiao X, Yu H, Bai X, Zhang C, Feng Z, Li L, Mei Y, Li X, Gou X
Journal of translational medicine 2025 Jul 11;23(1):785
Journal of translational medicine 2025 Jul 11;23(1):785
RO4929097 inhibits NICD3 to alleviate pulmonary hypertension via blocking Notch3/HIF-2α/FoxM1 signaling pathway.
Zhu H, Li C, Hu F, Wu L, Wu L, Zhou M, Liu W, Dai A
In vitro cellular & developmental biology. Animal 2025 Jan;61(1):107-116
In vitro cellular & developmental biology. Animal 2025 Jan;61(1):107-116
N6-methyladenosine-modified circRPS6KC1 regulated cellular senescence in prostate cancer via FOXM1/PCNA axis.
Shu X, Yi J, Li J, Ying Y, Tang Y, Chen Z, Wang J, Zhang F, Lu D, Wu Y, Sun J, Lin S, Qi Z, Chen D, Wang X, Chen H, Xie L, Ma X, Luo J
Cellular signalling 2025 Jan;125:111510
Cellular signalling 2025 Jan;125:111510
NEK2 Promotes ESCC Malignant Progression by Inhibiting Cellular Senescence via the FOXM1/c-Myc/p27 Signaling Pathway.
Li J, Wang Y, Wei S, Xu S, Dai S, Zhang L, Tian Z, Zhao L, Lv H
Molecular carcinogenesis 2025 Feb;64(2):244-259
Molecular carcinogenesis 2025 Feb;64(2):244-259
Organophosphate flame retardant triphenyl phosphate (TPhP) induced colonic fibrosis by bringing about epithelial-mesenchymal transition.
Peng C, Wang M, Zheng C, Zhang X, Chen Y, Wang L
Ecotoxicology and environmental safety 2025 Feb;291:117913
Ecotoxicology and environmental safety 2025 Feb;291:117913
Enhanced or reversible RNA N6-methyladenosine editing by red/far-red light induction.
Tang H, Han S, Jie Y, Jiang X, Zhang Y, Peng J, Wang F, Li X, Zhou X, Jiang W, Weng X
Nucleic acids research 2025 Feb 27;53(5)
Nucleic acids research 2025 Feb 27;53(5)
m6A reader IGF2BP2 mediates paclitaxel resistance in esophageal squamous cell carcinoma via FOXM1 mRNA stabilization.
Ren S, Wu J, Zhang L, Guan G, Jiang W
Oncology reports 2025 Dec;54(6)
Oncology reports 2025 Dec;54(6)
Abrogation of aberrant glycolytic interactions eliminates senescent cells and alleviates aging-related dysfunctions.
Mikawa T, Kameda M, Ikari S, Shibata E, Liu S, Miyagawa S, Ono K, Ito T, Yoshizawa A, Sugimoto M, Shibuya S, Shimizu T, Almunia J, Ogiso N, Revêchon G, Palazzo A, Bernard D, Kanda H, Soga T, Takubo K, Morioka S, Sasaki J, Sasaki T, Itamoto A, Fujii T, Seno H, Inagaki N, Kondoh H
Signal transduction and targeted therapy 2025 Dec 15;10(1):402
Signal transduction and targeted therapy 2025 Dec 15;10(1):402
TRIM47 Facilitates Osteosarcoma Progression via Destabilising FBP1 and Thus Activation of Wnt/β-Catenin Pathway.
Wang H, Chen X, Nie F, Zhong M, Fang Z, Qiu Z, Zhou L, Le Y, Wei X, Liao Y, Fang Z
Journal of cellular and molecular medicine 2025 Aug;29(15):e70753
Journal of cellular and molecular medicine 2025 Aug;29(15):e70753
Exploring the Molecular Mechanism of 1,25(OH)(2)D(3) Reversal of Sorafenib Resistance in Hepatocellular Carcinoma Based on Network Pharmacology and Experimental Validation.
Long Z, Wu X, Luo T, Chen X, Huang J, Zhang S
Current issues in molecular biology 2025 Apr 29;47(5)
Current issues in molecular biology 2025 Apr 29;47(5)
Down-regulation of microRNA-23a promotes pancreatic ductal adenocarcinoma initiation and progression by up-regulation of FOXM1 expression.
Liang L, Cai T, Li X, An J, Yu S, Zhang Y, Guo F, Wei F, He J, Xie K, Jiang T
Genes & diseases 2024 Sep;11(5):101203
Genes & diseases 2024 Sep;11(5):101203
Vascular restenosis following paclitaxel-coated balloon therapy is attributable to NLRP3 activation and LIN9 upregulation.
Kan Q, Peng Z, Wang K, Deng T, Zhou Z, Wu R, Yao C, Wang R
Journal of translational medicine 2024 Sep 27;22(1):871
Journal of translational medicine 2024 Sep 27;22(1):871
The role of forkhead box M1-methionine adenosyltransferase 2 A/2B axis in liver inflammation and fibrosis.
Yang B, Lu L, Xiong T, Fan W, Wang J, Barbier-Torres L, Chhimwal J, Sinha S, Tsuchiya T, Mavila N, Tomasi ML, Cao D, Zhang J, Peng H, Mato JM, Liu T, Yang X, Kalinichenko VV, Ramani K, Han J, Seki E, Yang H, Lu SC
Nature communications 2024 Sep 27;15(1):8388
Nature communications 2024 Sep 27;15(1):8388
Dibenzolium induces apoptosis and inhibits epithelial-mesenchymal transition (EMT) in bladder cancer cell lines.
Jotatsu Y, Arbiser JL, Moriwaki M, Hirata Y, Takeda S, Takada I, Chen KC, Sung SY, Shigemura K
Scientific reports 2024 Oct 26;14(1):25501
Scientific reports 2024 Oct 26;14(1):25501
CPT1A mediates radiation sensitivity in colorectal cancer.
Chen Z, Yu L, Zheng Z, Wang X, Guo Q, Chen Y, Zhang Y, Zhang Y, Xiao J, Chen K, Fan H, Ding Y
eLife 2024 Nov 28;13
eLife 2024 Nov 28;13
Activation of the FOXM1/ASF1B/PRDX3 axis confers hyperproliferative and antioxidative stress reactivity to gastric cancer.
Zhao Z, Cai Z, Zhang S, Yin X, Jiang T, Shen C, Yin Y, Sun H, Chen Z, Han J, Zhang B
Cancer letters 2024 May 1;589:216796
Cancer letters 2024 May 1;589:216796
OTUD7B knockdown inhibits the proliferation and stemness of breast cancer cells by destabilizing FOXM1.
Wang H, Han S, Xiao J, Fu X, Chen W, Zhuo D
Oncology letters 2024 Mar;27(3):102
Oncology letters 2024 Mar;27(3):102
Protective effect of Cyclo(His-Pro) on peritoneal fibrosis through regulation of HDAC3 expression.
Kim JE, Han D, Kim KH, Seo A, Moon JJ, Jeong JS, Kim JH, Kang E, Bae E, Kim YC, Lee JW, Cha RH, Kim DK, Oh KH, Kim YS, Jung HY, Yang SH
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jul;38(13):e23819
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jul;38(13):e23819
Huaier enhances the tumor-killing effect and reverses gemcitabine-induced stemness by suppressing FoxM1.
Wang Q, Gong M, Liu R, Mo J, Bai R, An R, Wang X, Han L, Wang Z, Ma Q, Wu Z, Zhou C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155656
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155656
A role for YAP/FOXM1/Nrf2 axis in oxidative stress and apoptosis of cataract induced by UVB irradiation.
Hong Y, Sun Y, Ainiwaer M, Xiao B, Zhang S, Ning L, Zhu X, Ji Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jul 31;38(14):e23832
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jul 31;38(14):e23832
AKT/FOXM1/STMN1 signaling pathway activation by SMC1A promotes tumor growth in breast cancer.
Li K, Dai P, Li J, Liu L, Cheng S, Fang Q, Wu B
The journal of gene medicine 2024 Jan;26(1):e3661
The journal of gene medicine 2024 Jan;26(1):e3661
Targeting FBXO22 enhances radiosensitivity in non-small cell lung cancer by inhibiting the FOXM1/Rad51 axis.
Chen Y, Zhou Y, Feng X, Wu Z, Yang Y, Rao X, Zhou R, Meng R, Dong X, Xu S, Zhang S, Wu G, Jie X
Cell death & disease 2024 Jan 31;15(1):104
Cell death & disease 2024 Jan 31;15(1):104
FOXM1 promote the growth and metastasis of uveal melanoma cells by regulating CDK2 expression.
Bai X, Li S, Luo Y
International ophthalmology 2024 Feb 11;44(1):55
International ophthalmology 2024 Feb 11;44(1):55
Novel benzothiazole/benzothiazole thiazolidine-2,4-dione derivatives as potential FOXM1 inhibitors: In silico, synthesis, and in vitro studies.
Abusharkh KAN, Comert Onder F, Çınar V, Onder A, Sıkık M, Hamurcu Z, Ozpolat B, Ay M
Archiv der Pharmazie 2024 Dec;357(12):e2400504
Archiv der Pharmazie 2024 Dec;357(12):e2400504
SNRPB2 promotes triple-negative breast cancer progression by controlling alternative splicing of MDM4 pre-mRNA.
Yu S, Si Y, Yu J, Jiang C, Cheng F, Xu M, Fan Z, Liu F, Liu C, Wang Y, Wang N, Liu C, Bi C, Sun H
Cancer science 2024 Dec;115(12):3915-3927
Cancer science 2024 Dec;115(12):3915-3927
FOXM1 c.1205 C > A mutation is associated with unilateral Moyamoya disease and inhibits angiogenesis in human brain endothelial cells.
Suo S, Fang C, Liu W, Liu Q, Zhang Z, Chang J, Li G
Human genetics 2024 Aug;143(8):939-953
Human genetics 2024 Aug;143(8):939-953
GAPDH: A common housekeeping gene with an oncogenic role in pan-cancer.
Wang J, Yu X, Cao X, Tan L, Jia B, Chen R, Li J
Computational and structural biotechnology journal 2023;21:4056-4069
Computational and structural biotechnology journal 2023;21:4056-4069
Ly6D facilitates chemoresistance in laryngeal squamous cell carcinoma through miR-509/β-catenin signaling pathway.
Wang J, Sheng N, Li Y, Fan Y, Nan X, Fu R
American journal of cancer research 2023;13(5):2155-2171
American journal of cancer research 2023;13(5):2155-2171
High-risk histological subtype-related FAM83A hijacked FOXM1 transcriptional regulation to promote malignant progression in lung adenocarcinoma.
Fei W, Yan Y, Liu G, Peng B, Liu Y, Chen Q
PeerJ 2023;11:e16306
PeerJ 2023;11:e16306
Increased α-HB links colorectal cancer and diabetes by potentiating NF-κB signaling.
Lv X, Ding P, Li L, Li L, Zhou D, Wang X, Chen J, Zhang W, Wang Q, Liao T, Wen W, Zhou D, Ji QH, He X, Lei QY, Hu W
Molecular metabolism 2023 Sep;75:101766
Molecular metabolism 2023 Sep;75:101766
A patient-derived organoid-based study identified an ASO targeting SNORD14E for endometrial cancer through reducing aberrant FOXM1 Expression and β-catenin nuclear accumulation.
Chen X, Liu X, Li QH, Lu BF, Xie BM, Ji YM, Zhao Y
Journal of experimental & clinical cancer research : CR 2023 Sep 5;42(1):230
Journal of experimental & clinical cancer research : CR 2023 Sep 5;42(1):230
Activation of LXRα attenuates 2-Ethylhexyl diphenyl phosphate (EHDPP) induced placental dysfunction.
Zhang Y, Liang J, Gu H, Du T, Xu P, Yu T, He Q, Huang Z, Lei S, Li J
Ecotoxicology and environmental safety 2023 Nov 1;266:115605
Ecotoxicology and environmental safety 2023 Nov 1;266:115605
K235 acetylation couples with PSPC1 to regulate the m(6)A demethylation activity of ALKBH5 and tumorigenesis.
Zhang XL, Chen XH, Xu B, Chen M, Zhu S, Meng N, Wang JZ, Zhu H, Chen D, Liu JB, Yan GR
Nature communications 2023 Jun 27;14(1):3815
Nature communications 2023 Jun 27;14(1):3815
MRPL51 is a downstream target of FOXM1 in promoting the malignant behaviors of lung adenocarcinoma.
Zhang W, Yu L, Xu C, Tang T, Cao J, Chen L, Pang X, Ren W
Oncology letters 2023 Jul;26(1):298
Oncology letters 2023 Jul;26(1):298
Comprehensive bioinformatics analysis reveals the significance of forkhead box family members in pancreatic adenocarcinoma.
Hu W, Li M, Wang Y, Zhong C, Si X, Shi X, Wang Z
Aging 2023 Jan 4;15(1):92-107
Aging 2023 Jan 4;15(1):92-107
ERCC6L facilitates the progression of laryngeal squamous cell carcinoma by the binding of FOXM1 and KIF4A.
Cui M, Chang Y, Wang J, Wu J, Li G, Tan J
Cell death discovery 2023 Feb 2;9(1):41
Cell death discovery 2023 Feb 2;9(1):41
Overexpression of FoxM1 optimizes the therapeutic effect of bone marrow mesenchymal stem cells on acute respiratory distress syndrome.
Luo Y, Ge S, Chen Q, Lin S, He W, Zeng M
Stem cell research & therapy 2023 Feb 14;14(1):27
Stem cell research & therapy 2023 Feb 14;14(1):27
Keratin 17 Impacts Global Gene Expression and Controls G2/M Cell Cycle Transition in Ionizing Radiation-Induced Skin Damage.
Yue Z, Lin J, Lu X, Gao Q, Pan M, Zhang Y, Shen S, Zhu WG, Paus R
The Journal of investigative dermatology 2023 Dec;143(12):2436-2446.e13
The Journal of investigative dermatology 2023 Dec;143(12):2436-2446.e13
Interactions between BRD4S, LOXL2, and MED1 drive cell cycle transcription in triple-negative breast cancer.
Pascual-Reguant L, Serra-Camprubí Q, Datta D, Cianferoni D, Kourtis S, Gañez-Zapater A, Cannatá C, Espinar L, Querol J, García-López L, Musa-Afaneh S, Guirola M, Gkanogiannis A, Miró Canturri A, Guzman M, Rodríguez O, Herencia-Ropero A, Arribas J, Serra V, Serrano L, Tian TV, Peiró S, Sdelci S
EMBO molecular medicine 2023 Dec 7;15(12):e18459
EMBO molecular medicine 2023 Dec 7;15(12):e18459
Hepatic vagotomy blunts liver regeneration after hepatectomy by downregulating the expression of interleukin-22.
Zhou H, Xu JL, Huang SX, He Y, He XW, Lu S, Yao B
World journal of gastrointestinal surgery 2023 Dec 27;15(12):2866-2878
World journal of gastrointestinal surgery 2023 Dec 27;15(12):2866-2878
HNRNPA2B1-mediated m6A modification of FOXM1 promotes drug resistance and inhibits ferroptosis in endometrial cancer via regulation of LCN2.
Jiang J, Zhu J, Qiu P, Ni J, Zhu W, Wang X
Functional & integrative genomics 2023 Dec 13;24(1):3
Functional & integrative genomics 2023 Dec 13;24(1):3
RNA-binding protein CCDC137 activates AKT signaling and promotes hepatocellular carcinoma through a novel non-canonical role of DGCR8 in mRNA localization.
Tao S, Xie SJ, Diao LT, Lv G, Hou YR, Hu YX, Xu WY, Du B, Xiao ZD
Journal of experimental & clinical cancer research : CR 2023 Aug 5;42(1):194
Journal of experimental & clinical cancer research : CR 2023 Aug 5;42(1):194
In silico, in vitro and in vivo studies: Dibutyl phthalate promotes prostate cancer cell proliferation by activating Forkhead Box M1 and remission after Natura-α pretreatment.
Bu H, Tang S, Liu G, Miao C, Zhou X, Yang H, Liu B
Toxicology 2023 Apr;488:153465
Toxicology 2023 Apr;488:153465
Coordinated activation of c-Src and FOXM1 drives tumor cell proliferation and breast cancer progression.
Nandi I, Smith HW, Sanguin-Gendreau V, Ji L, Pacis A, Papavasiliou V, Zuo D, Nam S, Attalla SS, Kim SH, Lusson S, Kuasne H, Fortier AM, Savage P, Martinez Ramirez C, Park M, Katzenellenbogen JA, Katzenellenbogen BS, Muller WJ
The Journal of clinical investigation 2023 Apr 3;133(7)
The Journal of clinical investigation 2023 Apr 3;133(7)
Knockdown MTDH Inhibits Glioma Proliferation and Migration and Promotes Apoptosis by Downregulating MYBL2.
Fu J, Peng J, Tu G
Mediators of inflammation 2022;2022:1706787
Mediators of inflammation 2022;2022:1706787
Characterizing and Targeting Genes Regulated by Transcription Factor MYBL2 in Lung Adenocarcinoma Cells.
Lee Y, Wu Z, Yang S, Schreiner SM, Gonzalez-Smith LD, Rhie SK
Cancers 2022 Oct 11;14(20)
Cancers 2022 Oct 11;14(20)
In vivo cyclic induction of the FOXM1 transcription factor delays natural and progeroid aging phenotypes and extends healthspan.
Ribeiro R, Macedo JC, Costa M, Ustiyan V, Shindyapina AV, Tyshkovskiy A, Gomes RN, Castro JP, Kalin TV, Vasques-Nóvoa F, Nascimento DS, Dmitriev SE, Gladyshev VN, Kalinichenko VV, Logarinho E
Nature aging 2022 May;2(5):397-411
Nature aging 2022 May;2(5):397-411
Induction of cancer cell stemness in glioma through glycolysis and the long noncoding RNA HULC-activated FOXM1/AGR2/HIF-1α axis.
Li YP, Liu Y, Xiao LM, Chen LK, Tao EX, Zeng EM, Xu CH
Laboratory investigation; a journal of technical methods and pathology 2022 Jul;102(7):691-701
Laboratory investigation; a journal of technical methods and pathology 2022 Jul;102(7):691-701
IFNα Potentiates Anti-PD-1 Efficacy by Remodeling Glucose Metabolism in the Hepatocellular Carcinoma Microenvironment.
Hu B, Yu M, Ma X, Sun J, Liu C, Wang C, Wu S, Fu P, Yang Z, He Y, Zhu Y, Huang C, Yang X, Shi Y, Qiu S, Sun H, Zhu AX, Zhou J, Xu Y, Zhu D, Fan J
Cancer discovery 2022 Jul 6;12(7):1718-1741
Cancer discovery 2022 Jul 6;12(7):1718-1741
The human FOXM1 homolog promotes basal progenitor cell proliferation and cortical folding in mouse.
Wang W, Su L, Ji F, Zhang D, Wang Y, Zhao J, Jiao RD, Zhang M, Huang E, Jiang H, Zhang J, Jiao J
EMBO reports 2022 Feb 3;23(3):e53602
EMBO reports 2022 Feb 3;23(3):e53602
A novel combination treatment of antiADAM17 antibody and erlotinib to overcome acquired drug resistance in non-small cell lung cancer through the FOXO3a/FOXM1 axis.
Li J, Chen P, Wu Q, Guo L, Leong KW, Chan KI, Kwok HF
Cellular and molecular life sciences : CMLS 2022 Dec 2;79(12):614
Cellular and molecular life sciences : CMLS 2022 Dec 2;79(12):614
Long noncoding RNA SH3PXD2A-AS1 promotes NSCLC proliferation and accelerates cell cycle progression by interacting with DHX9.
Zhou Y, Yong H, Cui W, Chu S, Li M, Li Z, Bai J, Zhang H
Cell death discovery 2022 Apr 11;8(1):192
Cell death discovery 2022 Apr 11;8(1):192
Comprehensive Analysis Uncovers Prognostic and Immunogenic Characteristics of Cellular Senescence for Lung Adenocarcinoma.
Lin W, Wang X, Wang Z, Shao F, Yang Y, Cao Z, Feng X, Gao Y, He J
Frontiers in cell and developmental biology 2021;9:780461
Frontiers in cell and developmental biology 2021;9:780461
Development of a novel gene signature to predict prognosis and response to PD-1 blockade in clear cell renal cell carcinoma.
Yin X, Wang Z, Wang J, Xu Y, Kong W, Zhang J
Oncoimmunology 2021;10(1):1933332
Oncoimmunology 2021;10(1):1933332
Paired-like homeodomain transcription factor 2 affects endometrial cell function and embryo implantation through the Wnt/β-catenin pathway.
Zhang H, Qi J, Guo J, Wang Y, Guan Y, Fan J, Sui L, Xu Y, Kong L, Yan B, Kong Y
Cell biology international 2021 Sep;45(9):1957-1965
Cell biology international 2021 Sep;45(9):1957-1965
The FOXM1/RNF26/p57 axis regulates the cell cycle to promote the aggressiveness of bladder cancer.
Yi L, Wang H, Li W, Ye K, Xiong W, Yu H, Jin X
Cell death & disease 2021 Oct 14;12(10):944
Cell death & disease 2021 Oct 14;12(10):944
NOX4-derived ROS-induced overexpression of FOXM1 regulates aerobic glycolysis in glioblastoma.
Su X, Yang Y, Yang Q, Pang B, Sun S, Wang Y, Qiao Q, Guo C, Liu H, Pang Q
BMC cancer 2021 Nov 5;21(1):1181
BMC cancer 2021 Nov 5;21(1):1181
FOXM1-activated SIRT4 inhibits NF-κB signaling and NLRP3 inflammasome to alleviate kidney injury and podocyte pyroptosis in diabetic nephropathy.
Xu X, Zhang L, Hua F, Zhang C, Zhang C, Mi X, Qin N, Wang J, Zhu A, Qin Z, Zhou F
Experimental cell research 2021 Nov 15;408(2):112863
Experimental cell research 2021 Nov 15;408(2):112863
HMMR is a downstream target of FOXM1 in enhancing proliferation and partial epithelial-to-mesenchymal transition of bladder cancer cells.
Yang D, Ma Y, Zhao P, Ma J, He C
Experimental cell research 2021 Nov 15;408(2):112860
Experimental cell research 2021 Nov 15;408(2):112860
Constitutive androstane receptor induced-hepatomegaly and liver regeneration is partially via yes-associated protein activation.
Gao Y, Fan S, Li H, Jiang Y, Yao X, Zhu S, Yang X, Wang R, Tian J, Gonzalez FJ, Huang M, Bi H
Acta pharmaceutica Sinica. B 2021 Mar;11(3):727-737
Acta pharmaceutica Sinica. B 2021 Mar;11(3):727-737
Fork head box M1 regulates vascular endothelial growth factor-A expression to promote the angiogenesis and tumor cell growth of gallbladder cancer.
Wang RT, Miao RC, Zhang X, Yang GH, Mu YP, Zhang ZY, Qu K, Liu C
World journal of gastroenterology 2021 Feb 28;27(8):692-707
World journal of gastroenterology 2021 Feb 28;27(8):692-707
Hsa_circ_0042823 accelerates cancer progression via miR-877-5p/FOXM1 axis in laryngeal squamous cell carcinoma.
Wu T, Sun Y, Sun Z, Li S, Wang W, Yu B, Wang G
Annals of medicine 2021 Dec;53(1):960-970
Annals of medicine 2021 Dec;53(1):960-970
LRPPRC regulates redox homeostasis via the circANKHD1/FOXM1 axis to enhance bladder urothelial carcinoma tumorigenesis.
Wei WS, Wang N, Deng MH, Dong P, Liu JY, Xiang Z, Li XD, Li ZY, Liu ZH, Peng YL, Li Z, Jiang LJ, Yao K, Ye YL, Lu WH, Zhang ZL, Zhou FJ, Liu ZW, Xie D, Yu CP
Redox biology 2021 Dec;48:102201
Redox biology 2021 Dec;48:102201
Schisandrol B promotes liver enlargement via activation of PXR and YAP pathways in mice.
Zhao YY, Yao XP, Jiao TY, Tian JN, Gao Y, Fan SC, Chen PP, Jiang YM, Zhou YY, Chen YX, Yang X, Huang M, Bi HC
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Apr;84:153520
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Apr;84:153520
miR-877-5p Suppresses Gastric Cancer Cell Proliferation Through Targeting FOXM1.
Wu K, Yu Z, Tang Z, Wei W, Xie D, Xie Y, Xiao Q
OncoTargets and therapy 2020;13:4731-4742
OncoTargets and therapy 2020;13:4731-4742
Dexamethasone-Induced Liver Enlargement Is Related to PXR/YAP Activation and Lipid Accumulation but Not Hepatocyte Proliferation.
Jiao T, Yao X, Zhao Y, Zhou Y, Gao Y, Fan S, Chen P, Li X, Jiang Y, Yang X, Gonzalez FJ, Huang M, Bi H
Drug metabolism and disposition: the biological fate of chemicals 2020 Sep;48(9):830-839
Drug metabolism and disposition: the biological fate of chemicals 2020 Sep;48(9):830-839
The differences of regulatory networks between papillary and anaplastic thyroid carcinoma: an integrative transcriptomics study.
Pan Z, Li L, Qian Y, Ge X, Hu X, Zhang Y, Ge M, Huang P
Cancer biology & therapy 2020 Sep 1;21(9):853-862
Cancer biology & therapy 2020 Sep 1;21(9):853-862
FoxM1 promotes the migration of ovarian cancer cell through KRT5 and KRT7.
Zhang Z, Tu K, Liu F, Liang M, Yu K, Wang Y, Luo Y, Yang B, Qin Y, He D, Jiang G, Huang O, Zou Y
Gene 2020 Oct 5;757:144947
Gene 2020 Oct 5;757:144947
miR-877-5p antagonizes the promoting effect of SP on the gastric cancer progression.
Guo XD, Zhang N, Sha L
Neoplasma 2020 Nov;67(6):1293-1302
Neoplasma 2020 Nov;67(6):1293-1302
LncRNA MFI2-AS1 promotes HCC progression and metastasis by acting as a competing endogenous RNA of miR-134 to upregulate FOXM1 expression.
Wei Y, Wang Z, Zong Y, Deng D, Chen P, Lu J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109890
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109890
A Cdh1-FoxM1-Apc axis controls muscle development and regeneration.
Chen Z, Li L, Xu S, Liu Z, Zhou C, Li Z, Liu Y, Wu W, Huang Y, Kuang M, Fan S, Li H, Li X, Song G, Wu WS, Chen J, Hou Y
Cell death & disease 2020 Mar 9;11(3):180
Cell death & disease 2020 Mar 9;11(3):180
circFOXM1 promotes proliferation of non-small cell lung carcinoma cells by acting as a ceRNA to upregulate FAM83D.
Yu C, Cheng Z, Cui S, Mao X, Li B, Fu Y, Wang H, Jin H, Ye Q, Zhao X, Jiang L, Qin W
Journal of experimental & clinical cancer research : CR 2020 Mar 30;39(1):55
Journal of experimental & clinical cancer research : CR 2020 Mar 30;39(1):55
MiR-346-5p promotes colorectal cancer cell proliferation in vitro and in vivo by targeting FBXL2 and activating the β-catenin signaling pathway.
Pan S, Wu W, Ren F, Li L, Li Y, Li W, Wang A, Liu D, Dong Y
Life sciences 2020 Mar 1;244:117300
Life sciences 2020 Mar 1;244:117300
UCHL3 promotes pancreatic cancer progression and chemo-resistance through FOXM1 stabilization.
Song Z, Li J, Zhang L, Deng J, Fang Z, Xiang X, Xiong J
American journal of cancer research 2019;9(9):1970-1981
American journal of cancer research 2019;9(9):1970-1981
Integrated Bioinformatics Analysis of Master Regulators in Anaplastic Thyroid Carcinoma.
Pan Z, Li L, Fang Q, Qian Y, Zhang Y, Zhu J, Ge M, Huang P
BioMed research international 2019;2019:9734576
BioMed research international 2019;2019:9734576
Promotion of liver growth by CAR is accompanied by Akt pathway activation and FoxM1-Nedd4-mediated repression of PTEN.
Yarushkin AA, Mazin ME, Pustylnyak YA, Prokopyeva EA, Pustylnyak VO
Archives of biochemistry and biophysics 2019 Sep 15;672:108065
Archives of biochemistry and biophysics 2019 Sep 15;672:108065
circTP63 functions as a ceRNA to promote lung squamous cell carcinoma progression by upregulating FOXM1.
Cheng Z, Yu C, Cui S, Wang H, Jin H, Wang C, Li B, Qin M, Yang C, He J, Zuo Q, Wang S, Liu J, Ye W, Lv Y, Zhao F, Yao M, Jiang L, Qin W
Nature communications 2019 Jul 19;10(1):3200
Nature communications 2019 Jul 19;10(1):3200
Suppression of Hepatocellular Carcinoma Progression through FOXM1 and EMT Inhibition via Hydroxygenkwanin-Induced miR-320a Expression.
Chou LF, Chen CY, Yang WH, Chen CC, Chang JL, Leu YL, Liou MJ, Wang TH
Biomolecules 2019 Dec 21;10(1)
Biomolecules 2019 Dec 21;10(1)
Dynamically decreased miR-671-5p expression is associated with oncogenic transformation and radiochemoresistance in breast cancer.
Tan X, Li Z, Ren S, Rezaei K, Pan Q, Goldstein AT, Macri CJ, Cao D, Brem RF, Fu SW
Breast cancer research : BCR 2019 Aug 7;21(1):89
Breast cancer research : BCR 2019 Aug 7;21(1):89
PARI functions as a new transcriptional target of FOXM1 involved in gastric cancer development.
Zhang Y, Ye X, Chen L, Wu Q, Gao Y, Li Y
International journal of biological sciences 2018;14(5):531-541
International journal of biological sciences 2018;14(5):531-541
Expression and functional characterization of FOXM1 in non-small cell lung cancer.
Zhang Y, Qiao WB, Shan L
OncoTargets and therapy 2018;11:3385-3393
OncoTargets and therapy 2018;11:3385-3393
3-O-acetyl-11-keto-β-boswellic acid exerts anti-tumor effects in glioblastoma by arresting cell cycle at G2/M phase.
Li W, Liu J, Fu W, Zheng X, Ren L, Liu S, Wang J, Ji T, Du G
Journal of experimental & clinical cancer research : CR 2018 Jul 3;37(1):132
Journal of experimental & clinical cancer research : CR 2018 Jul 3;37(1):132
FoxM1 repression during human aging leads to mitotic decline and aneuploidy-driven full senescence.
Macedo JC, Vaz S, Bakker B, Ribeiro R, Bakker PL, Escandell JM, Ferreira MG, Medema R, Foijer F, Logarinho E
Nature communications 2018 Jul 19;9(1):2834
Nature communications 2018 Jul 19;9(1):2834
Vagus-macrophage-hepatocyte link promotes post-injury liver regeneration and whole-body survival through hepatic FoxM1 activation.
Izumi T, Imai J, Yamamoto J, Kawana Y, Endo A, Sugawara H, Kohata M, Asai Y, Takahashi K, Kodama S, Kaneko K, Gao J, Uno K, Sawada S, Kalinichenko VV, Ishigaki Y, Yamada T, Katagiri H
Nature communications 2018 Dec 13;9(1):5300
Nature communications 2018 Dec 13;9(1):5300
Minute Virus of Mice Inhibits Transcription of the Cyclin B1 Gene during Infection.
Fuller MS, Majumder K, Pintel DJ
Journal of virology 2017 Jul 15;91(14)
Journal of virology 2017 Jul 15;91(14)
FOXM1 regulates glycolysis in hepatocellular carcinoma by transactivating glucose transporter 1 expression.
Shang R, Pu M, Li Y, Wang D
Oncology reports 2017 Apr;37(4):2261-2269
Oncology reports 2017 Apr;37(4):2261-2269
Association between FOXM1 and hedgehog signaling pathway in human cervical carcinoma by tissue microarray analysis.
Chen H, Wang J, Yang H, Chen D, Li P
Oncology letters 2016 Oct;12(4):2664-2673
Oncology letters 2016 Oct;12(4):2664-2673
Microarray-based gene expression profiling reveals genes and pathways involved in the oncogenic function of REG3A on pancreatic cancer cells.
Xu Q, Fu R, Yin G, Liu X, Liu Y, Xiang M
Gene 2016 Mar 10;578(2):263-73
Gene 2016 Mar 10;578(2):263-73
miR-671-5p inhibits epithelial-to-mesenchymal transition by downregulating FOXM1 expression in breast cancer.
Tan X, Fu Y, Chen L, Lee W, Lai Y, Rezaei K, Tabbara S, Latham P, Teal CB, Man YG, Siegel RS, Brem RF, Fu SW
Oncotarget 2016 Jan 5;7(1):293-307
Oncotarget 2016 Jan 5;7(1):293-307
LncBRM initiates YAP1 signalling activation to drive self-renewal of liver cancer stem cells.
Zhu P, Wang Y, Wu J, Huang G, Liu B, Ye B, Du Y, Gao G, Tian Y, He L, Fan Z
Nature communications 2016 Dec 1;7:13608
Nature communications 2016 Dec 1;7:13608
POH1 deubiquitylates and stabilizes E2F1 to promote tumour formation.
Wang B, Ma A, Zhang L, Jin WL, Qian Y, Xu G, Qiu B, Yang Z, Liu Y, Xia Q, Liu Y
Nature communications 2015 Oct 29;6:8704
Nature communications 2015 Oct 29;6:8704
Silibinin-induced glioma cell apoptosis by PI3K-mediated but Akt-independent downregulation of FoxM1 expression.
Zhang M, Liu Y, Gao Y, Li S
European journal of pharmacology 2015 Oct 15;765:346-54
European journal of pharmacology 2015 Oct 15;765:346-54
Protective effects of calycosin against CCl4-induced liver injury with activation of FXR and STAT3 in mice.
Chen X, Meng Q, Wang C, Liu Q, Sun H, Huo X, Sun P, Yang X, Peng J, Liu K
Pharmaceutical research 2015 Feb;32(2):538-48
Pharmaceutical research 2015 Feb;32(2):538-48
Overexpression of FOXM1 predicts poor prognosis and promotes cancer cell proliferation, migration and invasion in epithelial ovarian cancer.
Wen N, Wang Y, Wen L, Zhao SH, Ai ZH, Wang Y, Wu B, Lu HX, Yang H, Liu WC, Li Y
Journal of translational medicine 2014 May 20;12:134
Journal of translational medicine 2014 May 20;12:134
Effects of metformin on FOXM1 expression and on the biological behavior of acute leukemia cell lines.
Zhang B, Liu LL, Mao X, Zhang DH
Molecular medicine reports 2014 Dec;10(6):3193-8
Molecular medicine reports 2014 Dec;10(6):3193-8
Expression and significance of FOXM1 in human cervical cancer: a tissue micro-array study.
Guan P, Chen H, Li HJ, Duan J, Chen JY
Clinical and investigative medicine. Medecine clinique et experimentale 2011 Feb 1;34(1):E1-7
Clinical and investigative medicine. Medecine clinique et experimentale 2011 Feb 1;34(1):E1-7
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse thymus tissue were subjected to SDS PAGE followed by western blot with 13147-1-AP(FOXM1 antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The FOXM1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human FOXM1. This antibody recognizes human,mouse,rat antigen. The FOXM1 antibody has been validated for the following applications: ELISA, WB, IP analysis.
