Antibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 20964-1-AP - Provider product page

- Provider
- Proteintech Group
- Product name
- EDNRB antibody
- Antibody type
- Polyclonal
- Description
- EDNRB antibody (Cat. #20964-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: FC, IHC, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references TRPM7 inhibition alleviates acute gouty arthritis in mice by suppressing M1 polarization through the EDN1/EDNRB axis.
Huangqi Guizhi Wuwu decoction alleviate Oxaliplatin-Induced Peripheral Neuropathy by adjusting the myelin regeneration.
Influence of Atherosclerosis-Associated Risk Factors on Expression of Endothelin Receptors in Advanced Atherosclerosis.
Differentiation of lung tissue-resident c-Kit(+) cells into microvascular endothelial cells alleviates pulmonary vascular remodeling.
EDNRB inhibits the growth and migration of prostate cancer cells by activating the cGMP-PKG pathway.
Comprehensive bioinformatics analysis identifies metabolic and immune-related diagnostic biomarkers shared between diabetes and COPD using multi-omics and machine learning.
Functions of retinal astrocytes and Müller cells in mammalian myopia.
The immunosuppressive role of Edn3 overexpression in the melanoma microenvironment.
Nucleic acid ligands act as a PAM and agonist depending on the intrinsic ligand binding state of P2RY2.
Minimally modified low-density lipoprotein upregulates the ET(B) and α(1) receptors in mouse mesenteric arteries in vivo by activating the PI3K/Akt pathway.
Tail vein injection of mmLDL upregulates mouse mesenteric artery ET(B) receptors via activation of the ERK1/2 pathway.
Wu S, Zhang Y, Jiang C, Zhang Y, Yu P, Zhao W, Wang Z, Chen Y, Cheng Y, Ding J, Xu Y, Zhao Y, Zhou R, Hu W
International immunopharmacology 2026 Jun 15;179:116624
International immunopharmacology 2026 Jun 15;179:116624
Huangqi Guizhi Wuwu decoction alleviate Oxaliplatin-Induced Peripheral Neuropathy by adjusting the myelin regeneration.
Yang X, Zhu H, Li Z, Wang Q, Gao Y, Li Z, Tao L, Li L, Sun D, Zhang L, Shen W, Cheng H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157039
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157039
Influence of Atherosclerosis-Associated Risk Factors on Expression of Endothelin Receptors in Advanced Atherosclerosis.
Herbers O, Höltke C, Usai MV, Hochhalter J, Mallik M, Wildgruber M, Helfen A, Stölting M
International journal of molecular sciences 2025 Mar 5;26(5)
International journal of molecular sciences 2025 Mar 5;26(5)
Differentiation of lung tissue-resident c-Kit(+) cells into microvascular endothelial cells alleviates pulmonary vascular remodeling.
Li J, Zhou Y, Shu T, Lei W, Tang Q, Yang Y, Zhang J, Chen W, Zhou B, Hu Q, Xing Y, Wang J, Wang C
Developmental cell 2025 Jun 9;60(11):1601-1617.e7
Developmental cell 2025 Jun 9;60(11):1601-1617.e7
EDNRB inhibits the growth and migration of prostate cancer cells by activating the cGMP-PKG pathway.
Li X, Liu B, Wang S, Dong Q, Li J
Open medicine (Warsaw, Poland) 2024;19(1):20230875
Open medicine (Warsaw, Poland) 2024;19(1):20230875
Comprehensive bioinformatics analysis identifies metabolic and immune-related diagnostic biomarkers shared between diabetes and COPD using multi-omics and machine learning.
Liang Q, Wang Y, Li Z
Frontiers in endocrinology 2024;15:1475958
Frontiers in endocrinology 2024;15:1475958
Functions of retinal astrocytes and Müller cells in mammalian myopia.
Zhang X, Yu X, Wen Y, Jin L, Zhang L, Zhu H, Zhang D, Xie C, Guo D, Tong J, Shen Y
BMC ophthalmology 2022 Nov 24;22(1):451
BMC ophthalmology 2022 Nov 24;22(1):451
The immunosuppressive role of Edn3 overexpression in the melanoma microenvironment.
Freitas JT, Lopez J, Llorian C, Boroni M, Kos L
Pigment cell & melanoma research 2021 Nov;34(6):1084-1093
Pigment cell & melanoma research 2021 Nov;34(6):1084-1093
Nucleic acid ligands act as a PAM and agonist depending on the intrinsic ligand binding state of P2RY2.
Takahashi M, Amano R, Ozawa M, Martinez A, Akita K, Nakamura Y
Proceedings of the National Academy of Sciences of the United States of America 2021 May 4;118(18)
Proceedings of the National Academy of Sciences of the United States of America 2021 May 4;118(18)
Minimally modified low-density lipoprotein upregulates the ET(B) and α(1) receptors in mouse mesenteric arteries in vivo by activating the PI3K/Akt pathway.
Zeng ZS, Lin J, Xu CB, Cao L, Chen C, Li J
The Journal of pharmacy and pharmacology 2019 Jun;71(6):937-944
The Journal of pharmacy and pharmacology 2019 Jun;71(6):937-944
Tail vein injection of mmLDL upregulates mouse mesenteric artery ET(B) receptors via activation of the ERK1/2 pathway.
Liu Y, Chen XL, Xu CB, Cao L, Lin J, Chen G, Li J
Vascular pharmacology 2017 Sep;96-98:33-39
Vascular pharmacology 2017 Sep;96-98:33-39
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- mouse placenta tissue were subjected to SDS PAGE followed by western blot with 20964-1-AP(EDNRB antibody) at dilution of 1:500
- Other comments
- WB
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Immunohistochemistry of paraffin-embedded human placenta tissue slide using 20964-1-AP( EDNRB Antibody) at dilution of 1:50 (under 10x lens)
- Other comments
- IHC