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- References [63]
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- Product number
- 21207-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21207-1-AP, RRID:AB_10734584
- Product name
- TET2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated TET2 antibody (Cat. #21207-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Decreased TET2/5-hmC reduces the integrity of the epidermal barrier via epigenetic dysregulation of filaggrin in psoriatic lesions.
DNA demethylase TET2-mediated reduction of HADHB expression contributes to cadmium-induced malignant progression of colorectal cancer.
Downregulation of TET2 Contributes to Nasal Polypogenesis Through Hypoxia-Inducible Factor 1α-Mediated Epithelial-to-Mesenchymal Transition.
Exploring the importance of m5c in the diagnosis and subtype classification of COPD using the GEO database.
Skeletal muscle TET3 promotes insulin resistance through destabilisation of PGC-1α.
A negative feedback loop between TET2 and leptin in adipocyte regulates body weight.
LncRNA NEAT1 suppresses cellular senescence in hepatocellular carcinoma via KIF11-dependent repression of CDKN2A.
DNA dioxygenases TET2 deficiency promotes cigarette smoke induced chronic obstructive pulmonary disease by inducing ferroptosis of lung epithelial cell.
TET2 deficiency promotes anxiety and depression-like behaviors by activating NLRP3/IL-1β pathway in microglia of allergic rhinitis mice.
Influenza A virus inhibits TET2 expression by endoribonuclease PA-X to attenuate type I interferon signaling and promote viral replication.
The role of TET2-mediated ROBO4 hypomethylation in the development of diabetic retinopathy.
Enhanced BPGM/2,3-DPG pathway activity suppresses glycolysis in hypoxic astrocytes via FIH-1 and TET2.
m(5)C-dependent cross-regulation between nuclear reader ALYREF and writer NSUN2 promotes urothelial bladder cancer malignancy through facilitating RABL6/TK1 mRNAs splicing and stabilization.
Metformin Improves Comorbid Depressive Symptoms in Mice with Allergic Rhinitis by Reducing Olfactory Bulb Damage.
Mutual regulation between GDF11 and TET2 prevents senescence of mesenchymal stem cells.
m6A-Modified circTET2 Interacting with HNRNPC Regulates Fatty Acid Oxidation to Promote the Proliferation of Chronic Lymphocytic Leukemia.
TET2 confers a mechanistic link of microRNA-210 and mtROS in hypoxia-suppressed spontaneous transient outward currents in uterine arteries of pregnant sheep.
A small-molecule degrader of TET3 as treatment for anorexia nervosa in an animal model.
RNA 5-Methylcytosine Regulators Contribute to Metabolism Heterogeneity and Predict Prognosis in Ovarian Cancer.
ROS attenuates TET2-dependent ZO-1 epigenetic expression in cerebral vascular endothelial cells.
TET2 Regulates 5-Hydroxymethylcytosine Signature and CD4(+) T-Cell Balance in Allergic Rhinitis.
Ascorbic acid 2-glucoside preconditioning enhances the ability of bone marrow mesenchymal stem cells in promoting wound healing.
HIF-1α mediates renal fibrosis by regulating metabolic remodeling of renal tubule epithelial cells.
Ascorbic acid induces salivary gland function through TET2/acetylcholine receptor signaling in aging SAMP1/Klotho (-/-) mice.
TET2 regulates immune tolerance in chronically activated mast cells.
Epigenetic Landscape of HIV-1 Infection in Primary Human Macrophage.
MgFe-LDH Nanoparticles: A Promising Leukemia Inhibitory Factor Replacement for Self-Renewal and Pluripotency Maintenance in Cultured Mouse Embryonic Stem Cells.
Loss of ten-eleven translocation 2 induces cardiac hypertrophy and fibrosis through modulating ERK signaling pathway.
DNA demethylase Tet2 suppresses cisplatin-induced acute kidney injury.
Redirected nuclear glutamate dehydrogenase supplies Tet3 with α-ketoglutarate in neurons.
The chromosomal protein SMCHD1 regulates DNA methylation and the 2c-like state of embryonic stem cells by antagonizing TET proteins.
Inhibition of NF-κB is required for oleanolic acid to downregulate PD-L1 by promoting DNA demethylation in gastric cancer cells.
Low shear stress induced vascular endothelial cell pyroptosis by TET2/SDHB/ROS pathway.
Hepatic glycogenolysis is determined by maternal high-calorie diet via methylation of Pygl and it is modified by oteocalcin administration in mice.
Experimental eye research / short communication format characterization of DNA hydroxymethylation in the ocular choroid.
Empagliflozin Alleviates Hepatic Steatosis by Activating the AMPK-TET2-Autophagy Pathway in vivo and in vitro.
Neuroprotective Effect of Piracetam against Cocaine-Induced Neuro Epigenetic Modification of DNA Methylation in Astrocytes.
Proteases Activate Pregnancy Neutrophils by a Protease-Activated Receptor 1 Pathway: Epigenetic Implications for Preeclampsia.
Restoration of TET2 deficiency inhibits tumor growth in head neck squamous cell carcinoma.
Developmental nicotine exposure engenders intergenerational downregulation and aberrant posttranslational modification of cardinal epigenetic factors in the frontal cortices, striata, and hippocampi of adolescent mice.
TET-Mediated Hypermethylation Primes SDH-Deficient Cells for HIF2α-Driven Mesenchymal Transition.
Reduction of Tet2 exacerbates early stage Alzheimer's pathology and cognitive impairments in 2×Tg-AD mice.
Protease Amplification of the Inflammatory Response Induced by Commensal Bacteria: Implications for Racial Disparity in Term and Preterm Birth.
Demethylation of HACE1 gene promoter by propofol promotes autophagy of human A549 cells.
Reprogramming of DNA methylation at NEUROD2-bound sequences during cortical neuron differentiation.
Aanat Knockdown and Melatonin Supplementation in Embryo Development: Involvement of Mitochondrial Function and DNA Methylation.
TGF-β signaling controls Foxp3 methylation and T reg cell differentiation by modulating Uhrf1 activity.
Pregnancy-Induced Physiologic Adaptation of the Abdominal Aorta Is Associated with Changes in Gene Expression and Genomic Methylation.
Hypermethylation of the Micro-RNA 145 Promoter Is the Key Regulator for NLRP3 Inflammasome-Induced Activation and Plaque Formation.
Ten-eleven translocation 2 demethylates the MMP9 promoter, and its down-regulation in preeclampsia impairs trophoblast migration and invasion.
Decrease of 5-hydroxymethylcytosine and TET1 with nuclear exclusion of TET2 in small intestinal neuroendocrine tumors.
The oncogene Etv5 promotes MET in somatic reprogramming and orchestrates epiblast/primitive endoderm specification during mESCs differentiation.
TET2 facilitates PPARγ agonist-mediated gene regulation and insulin sensitization in adipocytes.
TET2 Protects against oxLDL-Induced HUVEC Dysfunction by Upregulating the CSE/H(2)S System.
Epigenetic modification differences between fetal fibroblast cells and mesenchymal stem cells of the Arbas Cashmere goat.
Coordinate Regulation of TET2 and EBNA2 Controls the DNA Methylation State of Latent Epstein-Barr Virus.
Restricted TET2 Expression in Germinal Center Type B Cells Promotes Stringent Epstein-Barr Virus Latency.
A role for TET2 in parathyroid carcinoma.
Non-catalytic roles for TET1 protein negatively regulating neuronal differentiation through srGAP3 in neuroblastoma cells.
A Novel Function of TET2 in CNS: Sustaining Neuronal Survival.
Oxidized low-density lipoprotein inhibits THP-1-derived macrophage autophagy via TET2 down-regulation.
Dynamics of ten-eleven translocation hydroxylase family proteins and 5-hydroxymethylcytosine in oligodendrocyte differentiation.
TET1 exerts its tumor suppressor function by interacting with p53-EZH2 pathway in gastric cancer.
Zhang H, Jia T, Che D, Peng B, Chu Z, Song X, Zeng W, Geng S
Journal of dermatological science 2024 Mar;113(3):103-112
Journal of dermatological science 2024 Mar;113(3):103-112
DNA demethylase TET2-mediated reduction of HADHB expression contributes to cadmium-induced malignant progression of colorectal cancer.
Li L, Jiang M, Wang W, Cao X, Ma Q, Han J, Liu Z, Huang Y, Chen Y
Ecotoxicology and environmental safety 2024 Jul 15;280:116579
Ecotoxicology and environmental safety 2024 Jul 15;280:116579
Downregulation of TET2 Contributes to Nasal Polypogenesis Through Hypoxia-Inducible Factor 1α-Mediated Epithelial-to-Mesenchymal Transition.
Liu K, Xu Y
Clinical and experimental otorhinolaryngology 2024 Feb;17(1):64-77
Clinical and experimental otorhinolaryngology 2024 Feb;17(1):64-77
Exploring the importance of m5c in the diagnosis and subtype classification of COPD using the GEO database.
Wu J, Li X, Kong D, Zheng X, Du W, Zhang Y, Jiao Y, Li X
Gene 2024 Feb 15;895:147987
Gene 2024 Feb 15;895:147987
Skeletal muscle TET3 promotes insulin resistance through destabilisation of PGC-1α.
Liu B, Xie D, Huang X, Jin S, Dai Y, Sun X, Li D, Bennett AM, Diano S, Huang Y
Diabetologia 2024 Apr;67(4):724-737
Diabetologia 2024 Apr;67(4):724-737
A negative feedback loop between TET2 and leptin in adipocyte regulates body weight.
Zeng Q, Song J, Sun X, Wang D, Liao X, Ding Y, Hu W, Jiao Y, Mai W, Aini W, Wang F, Zhou H, Xie L, Mei Y, Tang Y, Xie Z, Wu H, Liu W, Deng T
Nature communications 2024 Apr 1;15(1):2825
Nature communications 2024 Apr 1;15(1):2825
LncRNA NEAT1 suppresses cellular senescence in hepatocellular carcinoma via KIF11-dependent repression of CDKN2A.
Chen D, Wang J, Li Y, Xu C, Fanzheng M, Zhang P, Liu L
Clinical and translational medicine 2023 Sep;13(9):e1418
Clinical and translational medicine 2023 Sep;13(9):e1418
DNA dioxygenases TET2 deficiency promotes cigarette smoke induced chronic obstructive pulmonary disease by inducing ferroptosis of lung epithelial cell.
Zeng Z, Li T, Liu X, Ma Y, Luo L, Wang Z, Zhao Z, Li H, He X, Zeng H, Tao Y, Chen Y
Redox biology 2023 Nov;67:102916
Redox biology 2023 Nov;67:102916
TET2 deficiency promotes anxiety and depression-like behaviors by activating NLRP3/IL-1β pathway in microglia of allergic rhinitis mice.
Gao Z, Lv H, Wang Y, Xie Y, Guan M, Xu Y
Molecular medicine (Cambridge, Mass.) 2023 Nov 27;29(1):160
Molecular medicine (Cambridge, Mass.) 2023 Nov 27;29(1):160
Influenza A virus inhibits TET2 expression by endoribonuclease PA-X to attenuate type I interferon signaling and promote viral replication.
Hu Y, Chen X, Ling Y, Zhou K, Han M, Wang X, Yue M, Li Y
PLoS pathogens 2023 Jul;19(7):e1011550
PLoS pathogens 2023 Jul;19(7):e1011550
The role of TET2-mediated ROBO4 hypomethylation in the development of diabetic retinopathy.
Zhao L, Xu H, Liu X, Cheng Y, Xie J
Journal of translational medicine 2023 Jul 10;21(1):455
Journal of translational medicine 2023 Jul 10;21(1):455
Enhanced BPGM/2,3-DPG pathway activity suppresses glycolysis in hypoxic astrocytes via FIH-1 and TET2.
E G, Sun B, Liu B, Xu G, He S, Wang Y, Feng L, Wei H, Zhang J, Chen J, Gao Y, Zhang E
Brain research bulletin 2023 Jan;192:36-46
Brain research bulletin 2023 Jan;192:36-46
m(5)C-dependent cross-regulation between nuclear reader ALYREF and writer NSUN2 promotes urothelial bladder cancer malignancy through facilitating RABL6/TK1 mRNAs splicing and stabilization.
Wang N, Chen RX, Deng MH, Wei WS, Zhou ZH, Ning K, Li YH, Li XD, Ye YL, Wen JH, Dong B, Zhang XP, Liu ZW, Zhou FJ
Cell death & disease 2023 Feb 18;14(2):139
Cell death & disease 2023 Feb 18;14(2):139
Metformin Improves Comorbid Depressive Symptoms in Mice with Allergic Rhinitis by Reducing Olfactory Bulb Damage.
Lv H, Gao Z, Wang Y, Chen S, Liu P, Xie Y, Guan M, Cong J, Xu Y
Neurochemical research 2023 Dec;48(12):3639-3651
Neurochemical research 2023 Dec;48(12):3639-3651
Mutual regulation between GDF11 and TET2 prevents senescence of mesenchymal stem cells.
Gao J, Wang H, Shen J, Liu X, Zhu X, Huang C, Li G, Sun Y, Liu Z, Sun YE, Liu H
Journal of cellular physiology 2023 Dec;238(12):2827-2840
Journal of cellular physiology 2023 Dec;238(12):2827-2840
m6A-Modified circTET2 Interacting with HNRNPC Regulates Fatty Acid Oxidation to Promote the Proliferation of Chronic Lymphocytic Leukemia.
Wu Z, Zuo X, Zhang W, Li Y, Gui R, Leng J, Shen H, Pan B, Fan L, Li J, Jin H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Dec;10(34):e2304895
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Dec;10(34):e2304895
TET2 confers a mechanistic link of microRNA-210 and mtROS in hypoxia-suppressed spontaneous transient outward currents in uterine arteries of pregnant sheep.
Hu XQ, Song R, Dasgupta C, Blood AB, Zhang L
The Journal of physiology 2023 Apr;601(8):1501-1514
The Journal of physiology 2023 Apr;601(8):1501-1514
A small-molecule degrader of TET3 as treatment for anorexia nervosa in an animal model.
Lv H, Catarino J, Li D, Liu B, Gao XB, Horvath TL, Huang Y
Proceedings of the National Academy of Sciences of the United States of America 2023 Apr 18;120(16):e2300015120
Proceedings of the National Academy of Sciences of the United States of America 2023 Apr 18;120(16):e2300015120
RNA 5-Methylcytosine Regulators Contribute to Metabolism Heterogeneity and Predict Prognosis in Ovarian Cancer.
Xu J, Liu X, Chen Y, Wang Y, Liu T, Yi P
Frontiers in cell and developmental biology 2022;10:807786
Frontiers in cell and developmental biology 2022;10:807786
ROS attenuates TET2-dependent ZO-1 epigenetic expression in cerebral vascular endothelial cells.
Wang L, Mao B, Fan K, Sun R, Zhang J, Liang H, Liu Y
Fluids and barriers of the CNS 2022 Sep 8;19(1):73
Fluids and barriers of the CNS 2022 Sep 8;19(1):73
TET2 Regulates 5-Hydroxymethylcytosine Signature and CD4(+) T-Cell Balance in Allergic Rhinitis.
Tan L, Fu L, Zheng L, Fan W, Tan H, Tao Z, Xu Y
Allergy, asthma & immunology research 2022 Mar;14(2):254-272
Allergy, asthma & immunology research 2022 Mar;14(2):254-272
Ascorbic acid 2-glucoside preconditioning enhances the ability of bone marrow mesenchymal stem cells in promoting wound healing.
Yi Y, Wu M, Zhou X, Xiong M, Tan Y, Yu H, Liu Z, Wu Y, Zhang Q
Stem cell research & therapy 2022 Mar 21;13(1):119
Stem cell research & therapy 2022 Mar 21;13(1):119
HIF-1α mediates renal fibrosis by regulating metabolic remodeling of renal tubule epithelial cells.
Liu D, Sun H, Li K, Zhao Z, Liu Z, Zhang G, Ge Y, Zhang J, Wang D, Leng Y
Biochemical and biophysical research communications 2022 Aug 27;618:15-23
Biochemical and biophysical research communications 2022 Aug 27;618:15-23
Ascorbic acid induces salivary gland function through TET2/acetylcholine receptor signaling in aging SAMP1/Klotho (-/-) mice.
Toan NK, Kim SA, Ahn SG
Aging 2022 Aug 11;14(15):6028-6046
Aging 2022 Aug 11;14(15):6028-6046
TET2 regulates immune tolerance in chronically activated mast cells.
Rigo R, Chelbi R, Agopian J, Letard S, Griffon A, Ghamlouch H, Vernerey J, Ladopoulos V, Voisset E, De Sepulveda P, Guittard G, Nunès JA, Bidaut G, Göttgens B, Weber M, Bernard OA, Dubreuil P, Soucie E
JCI insight 2022 Apr 8;7(7)
JCI insight 2022 Apr 8;7(7)
Epigenetic Landscape of HIV-1 Infection in Primary Human Macrophage.
Lu F, Zankharia U, Vladimirova O, Yi Y, Collman RG, Lieberman PM
Journal of virology 2022 Apr 13;96(7):e0016222
Journal of virology 2022 Apr 13;96(7):e0016222
MgFe-LDH Nanoparticles: A Promising Leukemia Inhibitory Factor Replacement for Self-Renewal and Pluripotency Maintenance in Cultured Mouse Embryonic Stem Cells.
He X, Zhu Y, Yang L, Wang Z, Wang Z, Feng J, Wen X, Cheng L, Zhu R
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 May;8(9):2003535
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 May;8(9):2003535
Loss of ten-eleven translocation 2 induces cardiac hypertrophy and fibrosis through modulating ERK signaling pathway.
Tao H, Xu W, Qu W, Gao H, Zhang J, Cheng X, Liu N, Chen J, Xu GL, Li X, Shu Q
Human molecular genetics 2021 May 29;30(10):865-879
Human molecular genetics 2021 May 29;30(10):865-879
DNA demethylase Tet2 suppresses cisplatin-induced acute kidney injury.
Bao Y, Bai M, Zhu H, Yuan Y, Wang Y, Zhang Y, Wang J, Xie X, Yao X, Mao J, Fu X, Chen J, Yang Y, Lin W
Cell death discovery 2021 Jun 17;7(1):167
Cell death discovery 2021 Jun 17;7(1):167
Redirected nuclear glutamate dehydrogenase supplies Tet3 with α-ketoglutarate in neurons.
Traube FR, Özdemir D, Sahin H, Scheel C, Glück AF, Geserich AS, Oganesian S, Kostidis S, Iwan K, Rahimoff R, Giorgio G, Müller M, Spada F, Biel M, Cox J, Giera M, Michalakis S, Carell T
Nature communications 2021 Jul 2;12(1):4100
Nature communications 2021 Jul 2;12(1):4100
The chromosomal protein SMCHD1 regulates DNA methylation and the 2c-like state of embryonic stem cells by antagonizing TET proteins.
Huang Z, Yu J, Cui W, Johnson BK, Kim K, Pfeifer GP
Science advances 2021 Jan;7(4)
Science advances 2021 Jan;7(4)
Inhibition of NF-κB is required for oleanolic acid to downregulate PD-L1 by promoting DNA demethylation in gastric cancer cells.
Lu X, Li Y, Yang W, Tao M, Dai Y, Xu J, Xu Q
Journal of biochemical and molecular toxicology 2021 Jan;35(1):e22621
Journal of biochemical and molecular toxicology 2021 Jan;35(1):e22621
Low shear stress induced vascular endothelial cell pyroptosis by TET2/SDHB/ROS pathway.
Chen J, Zhang J, Wu J, Zhang S, Liang Y, Zhou B, Wu P, Wei D
Free radical biology & medicine 2021 Jan;162:582-591
Free radical biology & medicine 2021 Jan;162:582-591
Hepatic glycogenolysis is determined by maternal high-calorie diet via methylation of Pygl and it is modified by oteocalcin administration in mice.
Kawakubo-Yasukochi T, Yano E, Kimura S, Nishinakagawa T, Mizokami A, Hayashi Y, Hatakeyama Y, Ohe K, Yasukochi A, Nakamura S, Jimi E, Hirata M
Molecular metabolism 2021 Dec;54:101360
Molecular metabolism 2021 Dec;54:101360
Experimental eye research / short communication format characterization of DNA hydroxymethylation in the ocular choroid.
Pomerleau J, Weidmann C, Coutant K, Lowry CM, Veilleux MP, Bérubé J, Wagner JR, Landreville S
Experimental eye research 2021 Apr;205:108473
Experimental eye research 2021 Apr;205:108473
Empagliflozin Alleviates Hepatic Steatosis by Activating the AMPK-TET2-Autophagy Pathway in vivo and in vitro.
Li T, Fang T, Xu L, Liu X, Li X, Xue M, Yu X, Sun B, Chen L
Frontiers in pharmacology 2020;11:622153
Frontiers in pharmacology 2020;11:622153
Neuroprotective Effect of Piracetam against Cocaine-Induced Neuro Epigenetic Modification of DNA Methylation in Astrocytes.
Sivalingam K, Samikkannu T
Brain sciences 2020 Sep 5;10(9)
Brain sciences 2020 Sep 5;10(9)
Proteases Activate Pregnancy Neutrophils by a Protease-Activated Receptor 1 Pathway: Epigenetic Implications for Preeclampsia.
Walsh SW, Nugent WH, Al Dulaimi M, Washington SL, Dacha P, Strauss JF 3rd
Reproductive sciences (Thousand Oaks, Calif.) 2020 Nov;27(11):2115-2127
Reproductive sciences (Thousand Oaks, Calif.) 2020 Nov;27(11):2115-2127
Restoration of TET2 deficiency inhibits tumor growth in head neck squamous cell carcinoma.
Huang R, Wang Y, Ge H, Wang D, Wang Y, Zhang W, Yang J, Cheng J
Annals of translational medicine 2020 Mar;8(6):329
Annals of translational medicine 2020 Mar;8(6):329
Developmental nicotine exposure engenders intergenerational downregulation and aberrant posttranslational modification of cardinal epigenetic factors in the frontal cortices, striata, and hippocampi of adolescent mice.
Buck JM, O'Neill HC, Stitzel JA
Epigenetics & chromatin 2020 Mar 5;13(1):13
Epigenetics & chromatin 2020 Mar 5;13(1):13
TET-Mediated Hypermethylation Primes SDH-Deficient Cells for HIF2α-Driven Mesenchymal Transition.
Morin A, Goncalves J, Moog S, Castro-Vega LJ, Job S, Buffet A, Fontenille MJ, Woszczyk J, Gimenez-Roqueplo AP, Letouzé E, Favier J
Cell reports 2020 Mar 31;30(13):4551-4566.e7
Cell reports 2020 Mar 31;30(13):4551-4566.e7
Reduction of Tet2 exacerbates early stage Alzheimer's pathology and cognitive impairments in 2×Tg-AD mice.
Li L, Qiu Y, Miao M, Liu Z, Li W, Zhu Y, Wang Q
Human molecular genetics 2020 Jul 21;29(11):1833-1852
Human molecular genetics 2020 Jul 21;29(11):1833-1852
Protease Amplification of the Inflammatory Response Induced by Commensal Bacteria: Implications for Racial Disparity in Term and Preterm Birth.
Walsh SW, Nugent WH, Alam SMK, Washington SL, Teves M, Jefferson KK, Strauss JF 3rd
Reproductive sciences (Thousand Oaks, Calif.) 2020 Jan;27(1):246-259
Reproductive sciences (Thousand Oaks, Calif.) 2020 Jan;27(1):246-259
Demethylation of HACE1 gene promoter by propofol promotes autophagy of human A549 cells.
Li S, Yang H, Zhao M, Gong L, Wang Y, Lv Z, Quan Y, Wang Z
Oncology letters 2020 Dec;20(6):280
Oncology letters 2020 Dec;20(6):280
Reprogramming of DNA methylation at NEUROD2-bound sequences during cortical neuron differentiation.
Hahn MA, Jin SG, Li AX, Liu J, Huang Z, Wu X, Kim BW, Johnson J, Bilbao AV, Tao S, Yim JA, Fong Y, Goebbels S, Schwab MH, Lu Q, Pfeifer GP
Science advances 2019 Oct;5(10):eaax0080
Science advances 2019 Oct;5(10):eaax0080
Aanat Knockdown and Melatonin Supplementation in Embryo Development: Involvement of Mitochondrial Function and DNA Methylation.
Yang M, Tao J, Wu H, Guan S, Liu L, Zhang L, Deng S, He C, Ji P, Liu J, Liu G
Antioxidants & redox signaling 2019 Jun 20;30(18):2050-2065
Antioxidants & redox signaling 2019 Jun 20;30(18):2050-2065
TGF-β signaling controls Foxp3 methylation and T reg cell differentiation by modulating Uhrf1 activity.
Sun X, Cui Y, Feng H, Liu H, Liu X
The Journal of experimental medicine 2019 Dec 2;216(12):2819-2837
The Journal of experimental medicine 2019 Dec 2;216(12):2819-2837
Pregnancy-Induced Physiologic Adaptation of the Abdominal Aorta Is Associated with Changes in Gene Expression and Genomic Methylation.
Gelinne A, Brown L, Ko NL, Osol G, Brown S
Journal of vascular research 2018;55(5):319-327
Journal of vascular research 2018;55(5):319-327
Hypermethylation of the Micro-RNA 145 Promoter Is the Key Regulator for NLRP3 Inflammasome-Induced Activation and Plaque Formation.
Zhong W, Li B, Xu Y, Yang P, Chen R, Wang Z, Shao C, Song J, Yan J
JACC. Basic to translational science 2018 Oct;3(5):604-624
JACC. Basic to translational science 2018 Oct;3(5):604-624
Ten-eleven translocation 2 demethylates the MMP9 promoter, and its down-regulation in preeclampsia impairs trophoblast migration and invasion.
Li X, Wu C, Shen Y, Wang K, Tang L, Zhou M, Yang M, Pan T, Liu X, Xu W
The Journal of biological chemistry 2018 Jun 29;293(26):10059-10070
The Journal of biological chemistry 2018 Jun 29;293(26):10059-10070
Decrease of 5-hydroxymethylcytosine and TET1 with nuclear exclusion of TET2 in small intestinal neuroendocrine tumors.
Barazeghi E, Prabhawa S, Norlén O, Hellman P, Stålberg P, Westin G
BMC cancer 2018 Jul 25;18(1):764
BMC cancer 2018 Jul 25;18(1):764
The oncogene Etv5 promotes MET in somatic reprogramming and orchestrates epiblast/primitive endoderm specification during mESCs differentiation.
Zhang J, Cao H, Xie J, Fan C, Xie Y, He X, Liao M, Zhang S, Wang H
Cell death & disease 2018 Feb 14;9(2):224
Cell death & disease 2018 Feb 14;9(2):224
TET2 facilitates PPARγ agonist-mediated gene regulation and insulin sensitization in adipocytes.
Bian F, Ma X, Villivalam SD, You D, Choy LR, Paladugu A, Fung S, Kang S
Metabolism: clinical and experimental 2018 Dec;89:39-47
Metabolism: clinical and experimental 2018 Dec;89:39-47
TET2 Protects against oxLDL-Induced HUVEC Dysfunction by Upregulating the CSE/H(2)S System.
Peng J, Tang ZH, Ren Z, He B, Zeng Y, Liu LS, Wang Z, Wei DH, Zheng XL, Jiang ZS
Frontiers in pharmacology 2017;8:486
Frontiers in pharmacology 2017;8:486
Epigenetic modification differences between fetal fibroblast cells and mesenchymal stem cells of the Arbas Cashmere goat.
Wang X, Wang Z, Wang Q, Wang H, Liang H, Liu D
Research in veterinary science 2017 Oct;114:363-369
Research in veterinary science 2017 Oct;114:363-369
Coordinate Regulation of TET2 and EBNA2 Controls the DNA Methylation State of Latent Epstein-Barr Virus.
Lu F, Wiedmer A, Martin KA, Wickramasinghe PJMS, Kossenkov AV, Lieberman PM
Journal of virology 2017 Oct 15;91(20)
Journal of virology 2017 Oct 15;91(20)
Restricted TET2 Expression in Germinal Center Type B Cells Promotes Stringent Epstein-Barr Virus Latency.
Wille CK, Li Y, Rui L, Johannsen EC, Kenney SC
Journal of virology 2017 Mar 1;91(5)
Journal of virology 2017 Mar 1;91(5)
A role for TET2 in parathyroid carcinoma.
Barazeghi E, Gill AJ, Sidhu S, Norlén O, Dina R, Palazzo FF, Hellman P, Stålberg P, Westin G
Endocrine-related cancer 2017 Jul;24(7):329-338
Endocrine-related cancer 2017 Jul;24(7):329-338
Non-catalytic roles for TET1 protein negatively regulating neuronal differentiation through srGAP3 in neuroblastoma cells.
Gao J, Ma Y, Fu HL, Luo Q, Wang Z, Xiao YH, Yang H, Cui DX, Jin WL
Protein & cell 2016 May;7(5):351-61
Protein & cell 2016 May;7(5):351-61
A Novel Function of TET2 in CNS: Sustaining Neuronal Survival.
Mi Y, Gao X, Dai J, Ma Y, Xu L, Jin W
International journal of molecular sciences 2015 Sep 10;16(9):21846-57
International journal of molecular sciences 2015 Sep 10;16(9):21846-57
Oxidized low-density lipoprotein inhibits THP-1-derived macrophage autophagy via TET2 down-regulation.
Li G, Peng J, Liu Y, Li X, Yang Q, Li Y, Tang Z, Wang Z, Jiang Z, Wei D
Lipids 2015 Feb;50(2):177-83
Lipids 2015 Feb;50(2):177-83
Dynamics of ten-eleven translocation hydroxylase family proteins and 5-hydroxymethylcytosine in oligodendrocyte differentiation.
Zhao X, Dai J, Ma Y, Mi Y, Cui D, Ju G, Macklin WB, Jin W
Glia 2014 Jun;62(6):914-26
Glia 2014 Jun;62(6):914-26
TET1 exerts its tumor suppressor function by interacting with p53-EZH2 pathway in gastric cancer.
Fu HL, Ma Y, Lu LG, Hou P, Li BJ, Jin WL, Cui DX
Journal of biomedical nanotechnology 2014 Jul;10(7):1217-30
Journal of biomedical nanotechnology 2014 Jul;10(7):1217-30
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human brain tissue were subjected to SDS PAGE followed by western blot with 21207-1-AP(TET2 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The TET2 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human TET2. This antibody recognizes human, mouse antigen. The TET2 antibody has been validated for the following applications: ELISA, WB, IP analysis.
