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- References [9]
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- Western blot [1]
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- Product number
- 17078-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17078-1-AP, RRID:AB_2199389
- Product name
- TBC1D5 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated TBC1D5 antibody (Cat. #17078-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references TBC1D5 reverses the capability of HIF-2α in tumor progression and lipid metabolism in clear cell renal cell carcinoma by regulating the autophagy.
Hepatitis B virus core protein as a Rab-GAP suppressor driving liver disease progression.
TBK1 Facilitates GLUT1-Dependent Glucose Consumption by suppressing mTORC1 Signaling in Colorectal Cancer Progression.
BioID reveals an ATG9A interaction with ATG13-ATG101 in the degradation of p62/SQSTM1-ubiquitin clusters.
De novo macrocyclic peptides for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex.
Retromer and TBC1D5 maintain late endosomal RAB7 domains to enable amino acid-induced mTORC1 signaling.
TBC1D5 controls the GTPase cycle of Rab7b.
Control of RAB7 activity and localization through the retromer-TBC1D5 complex enables RAB7-dependent mitophagy.
Trafficking defects in WASH-knockout fibroblasts originate from collapsed endosomal and lysosomal networks.
Huang Y, Xiong Z, Wang J, Gao Y, Cao Q, Wang D, Shi J, Chen Z, Yang X
Journal of translational medicine 2024 Feb 28;22(1):212
Journal of translational medicine 2024 Feb 28;22(1):212
Hepatitis B virus core protein as a Rab-GAP suppressor driving liver disease progression.
Su Y, Bu F, Zhu Y, Yang L, Wu Q, Zheng Y, Zhao J, Yu L, Jiang N, Wang Y, Wu J, Xie Y, Zhang X, Gao Y, Lan K, Deng Q
Science bulletin 2024 Aug 30;69(16):2580-2595
Science bulletin 2024 Aug 30;69(16):2580-2595
TBK1 Facilitates GLUT1-Dependent Glucose Consumption by suppressing mTORC1 Signaling in Colorectal Cancer Progression.
Zhou D, Yao Y, Zong L, Zhou G, Feng M, Chen J, Liu G, Chen G, Sun K, Yao H, Liu Y, Shi X, Zhang W, Shi B, Tai Q, Wu G, Sun L, Hu W, Zhu X, He S
International journal of biological sciences 2022;18(8):3374-3389
International journal of biological sciences 2022;18(8):3374-3389
BioID reveals an ATG9A interaction with ATG13-ATG101 in the degradation of p62/SQSTM1-ubiquitin clusters.
Kannangara AR, Poole DM, McEwan CM, Youngs JC, Weerasekara VK, Thornock AM, Lazaro MT, Balasooriya ER, Oh LM, Soderblom EJ, Lee JJ, Simmons DL, Andersen JL
EMBO reports 2021 Oct 5;22(10):e51136
EMBO reports 2021 Oct 5;22(10):e51136
De novo macrocyclic peptides for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex.
Chen KE, Guo Q, Hill TA, Cui Y, Kendall AK, Yang Z, Hall RJ, Healy MD, Sacharz J, Norwood SJ, Fonseka S, Xie B, Reid RC, Leneva N, Parton RG, Ghai R, Stroud DA, Fairlie DP, Suga H, Jackson LP, Teasdale RD, Passioura T, Collins BM
Science advances 2021 Dec 3;7(49):eabg4007
Science advances 2021 Dec 3;7(49):eabg4007
Retromer and TBC1D5 maintain late endosomal RAB7 domains to enable amino acid-induced mTORC1 signaling.
Kvainickas A, Nägele H, Qi W, Dokládal L, Jimenez-Orgaz A, Stehl L, Gangurde D, Zhao Q, Hu Z, Dengjel J, De Virgilio C, Baumeister R, Steinberg F
The Journal of cell biology 2019 Sep 2;218(9):3019-3038
The Journal of cell biology 2019 Sep 2;218(9):3019-3038
TBC1D5 controls the GTPase cycle of Rab7b.
Borg Distefano M, Hofstad Haugen L, Wang Y, Perdreau-Dahl H, Kjos I, Jia D, Morth JP, Neefjes J, Bakke O, Progida C
Journal of cell science 2018 Sep 3;131(17)
Journal of cell science 2018 Sep 3;131(17)
Control of RAB7 activity and localization through the retromer-TBC1D5 complex enables RAB7-dependent mitophagy.
Jimenez-Orgaz A, Kvainickas A, Nägele H, Denner J, Eimer S, Dengjel J, Steinberg F
The EMBO journal 2018 Jan 17;37(2):235-254
The EMBO journal 2018 Jan 17;37(2):235-254
Trafficking defects in WASH-knockout fibroblasts originate from collapsed endosomal and lysosomal networks.
Gomez TS, Gorman JA, de Narvajas AA, Koenig AO, Billadeau DD
Molecular biology of the cell 2012 Aug;23(16):3215-28
Molecular biology of the cell 2012 Aug;23(16):3215-28
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The TBC1D5 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human TBC1D5. This antibody recognizes human, mouse, rat antigen. The TBC1D5 antibody has been validated for the following applications: ELISA, WB analysis.
