Antibody data
- Antibody Data
- Antigen structure
- References [23]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [1]
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Validation data
Reference
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- Product number
- 13295-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13295-1-AP, RRID:AB_2071993
- Product name
- Cyclin A1 antibody
- Antibody type
- Polyclonal
- Description
- Cyclin A1 antibody (Cat. #13295-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction.
Screening of potential hub genes involved in Kidney Wilms tumor via bioinformatics analysis and experimental validation.
Aurora kinase B disruption suppresses pathological retinal angiogenesis by affecting cell cycle progression.
Improved anti-tumor activity of fluorinated camptothecin derivatives 9-fluorocamptothecin and 7-ethyl-9-fluorocamptothecin on hepatocellular carcinoma by targeting topoisomerase I.
GPR146 regulates pulmonary vascular remodeling by promoting pulmonary artery smooth muscle cell proliferation through 5-lipoxygenase.
The mechanism of the imbalance between proliferation and ferroptosis in pulmonary artery smooth muscle cells based on the activation of SLC7A11.
Metformin inhibits pulmonary artery smooth muscle cell proliferation by upregulating p21 via NONRATT015587.2.
NDUFA4L2 in smooth muscle promotes vascular remodeling in hypoxic pulmonary arterial hypertension.
LncRNA CAR10 Upregulates PDPK1 to Promote Cervical Cancer Development by Sponging miR-125b-5p.
LncRNA AY343892 inhibits breast cancer development by positively regulating BRCA1-mediated transcription of PTEN.
BAF45D knockdown decreases cell viability, inhibits colony formation, induces cell apoptosis and S-phase arrest in human pancreatic cancer cells.
Long non‑coding RNA MALAT1 sponges miR‑124‑3p.1/KLF5 to promote pulmonary vascular remodeling and cell cycle progression of pulmonary artery hypertension.
Cyclin-dependent kinase 1 disruption inhibits angiogenesis by inducing cell cycle arrest and apoptosis.
Baicalin inhibits proliferation and promotes apoptosis of vascular smooth muscle cells by regulating the MEG3/p53 pathway following treatment with ox‑LDL.
Biocompatible PEGylated Gold nanorods function As cytokinesis inhibitors to suppress angiogenesis.
Cloning, expression pattern, and potential role of apoptosis inhibitor 5 in the termination of embryonic diapause and early embryo development of Artemia sinica.
RPL10L Is Required for Male Meiotic Division by Compensating for RPL10 during Meiotic Sex Chromosome Inactivation in Mice.
Doxorubicin and resveratrol co-delivery nanoparticle to overcome doxorubicin resistance.
The role of RhoA in vulvar squamous cell carcinoma: a carcinogenesis, progression, and target therapy marker.
Dioscin suppresses human laryngeal cancer cells growth via induction of cell-cycle arrest and MAPK-mediated mitochondrial-derived apoptosis and inhibition of tumor invasion.
MicroRNA-505 functions as a tumor suppressor in endometrial cancer by targeting TGF-α.
Paper-based microreactor array for rapid screening of cell signaling cascades.
BMP-6 inhibits cell proliferation by targeting microRNA-192 in breast cancer.
Zhang X, He L, Li Y, Qiu Y, Hu W, Lu W, Du H, Yang D
Oncology reports 2024 May;51(5)
Oncology reports 2024 May;51(5)
Screening of potential hub genes involved in Kidney Wilms tumor via bioinformatics analysis and experimental validation.
Zeng Q, Liu T, Qin L, Wang C, Peng G, Liu Z, Tao J
BMC cancer 2024 Jun 27;24(1):771
BMC cancer 2024 Jun 27;24(1):771
Aurora kinase B disruption suppresses pathological retinal angiogenesis by affecting cell cycle progression.
Zhu W, Gui X, Zhou Y, Gao X, Zhang R, Li Q, Zhang H, Zhao J, Cui X, Gao G, Tang H, Huan C, Pan D, Song H, Zhou Z, Shen W
Experimental eye research 2024 Feb;239:109753
Experimental eye research 2024 Feb;239:109753
Improved anti-tumor activity of fluorinated camptothecin derivatives 9-fluorocamptothecin and 7-ethyl-9-fluorocamptothecin on hepatocellular carcinoma by targeting topoisomerase I.
Zhang M, Zhu LZ, Yang CJ, Yan JX, Wang ZP, Bai YP, Peng LZ, Luo HB, Zhang ZJ, Li L, Xu CR, Liu YQ
Bioorganic chemistry 2023 Oct;139:106652
Bioorganic chemistry 2023 Oct;139:106652
GPR146 regulates pulmonary vascular remodeling by promoting pulmonary artery smooth muscle cell proliferation through 5-lipoxygenase.
Huang J, Xie Y, Chen B, Xia Y, Jiang Y, Sun Z, Liu Y
European journal of pharmacology 2023 Dec 15;961:176123
European journal of pharmacology 2023 Dec 15;961:176123
The mechanism of the imbalance between proliferation and ferroptosis in pulmonary artery smooth muscle cells based on the activation of SLC7A11.
Hu P, Xu Y, Jiang Y, Huang J, Liu Y, Wang D, Tao T, Sun Z, Liu Y
European journal of pharmacology 2022 Aug 5;928:175093
European journal of pharmacology 2022 Aug 5;928:175093
Metformin inhibits pulmonary artery smooth muscle cell proliferation by upregulating p21 via NONRATT015587.2.
Sun Z, Liu Y, Hu R, Wang T, Li Y, Liu N
International journal of molecular medicine 2022 Apr;49(4)
International journal of molecular medicine 2022 Apr;49(4)
NDUFA4L2 in smooth muscle promotes vascular remodeling in hypoxic pulmonary arterial hypertension.
Liu Y, Nie X, Zhu J, Wang T, Li Y, Wang Q, Sun Z
Journal of cellular and molecular medicine 2021 Jan;25(2):1221-1237
Journal of cellular and molecular medicine 2021 Jan;25(2):1221-1237
LncRNA CAR10 Upregulates PDPK1 to Promote Cervical Cancer Development by Sponging miR-125b-5p.
Hu T, Zhang Q, Gao L
BioMed research international 2020;2020:4351671
BioMed research international 2020;2020:4351671
LncRNA AY343892 inhibits breast cancer development by positively regulating BRCA1-mediated transcription of PTEN.
Li Y, Zhang M, Li F
Histology and histopathology 2020 Oct;35(10):1171-1180
Histology and histopathology 2020 Oct;35(10):1171-1180
BAF45D knockdown decreases cell viability, inhibits colony formation, induces cell apoptosis and S-phase arrest in human pancreatic cancer cells.
Liu Z, Liu L, Sun R, Liu C
Bioscience, biotechnology, and biochemistry 2020 Jun;84(6):1146-1152
Bioscience, biotechnology, and biochemistry 2020 Jun;84(6):1146-1152
Long non‑coding RNA MALAT1 sponges miR‑124‑3p.1/KLF5 to promote pulmonary vascular remodeling and cell cycle progression of pulmonary artery hypertension.
Wang D, Xu H, Wu B, Jiang S, Pan H, Wang R, Chen J
International journal of molecular medicine 2019 Sep;44(3):871-884
International journal of molecular medicine 2019 Sep;44(3):871-884
Cyclin-dependent kinase 1 disruption inhibits angiogenesis by inducing cell cycle arrest and apoptosis.
Gao X, Zhang Y, Zhang R, Zhao Z, Zhang H, Wu J, Shen W, Zhong M
Experimental and therapeutic medicine 2019 Oct;18(4):3062-3070
Experimental and therapeutic medicine 2019 Oct;18(4):3062-3070
Baicalin inhibits proliferation and promotes apoptosis of vascular smooth muscle cells by regulating the MEG3/p53 pathway following treatment with ox‑LDL.
Liu Y, Jia L, Min D, Xu Y, Zhu J, Sun Z
International journal of molecular medicine 2019 Feb;43(2):901-913
International journal of molecular medicine 2019 Feb;43(2):901-913
Biocompatible PEGylated Gold nanorods function As cytokinesis inhibitors to suppress angiogenesis.
Song H, Guo T, Zhao Z, Wei Y, Luo H, Weng W, Zhang R, Zhong M, Chen C, Su J, Shen W
Biomaterials 2018 Sep;178:23-35
Biomaterials 2018 Sep;178:23-35
Cloning, expression pattern, and potential role of apoptosis inhibitor 5 in the termination of embryonic diapause and early embryo development of Artemia sinica.
Zhang S, Yao F, Jing T, Zhang M, Zhao W, Zou X, Sui L, Hou L
Gene 2017 Sep 10;628:170-179
Gene 2017 Sep 10;628:170-179
RPL10L Is Required for Male Meiotic Division by Compensating for RPL10 during Meiotic Sex Chromosome Inactivation in Mice.
Jiang L, Li T, Zhang X, Zhang B, Yu C, Li Y, Fan S, Jiang X, Khan T, Hao Q, Xu P, Nadano D, Huleihel M, Lunenfeld E, Wang PJ, Zhang Y, Shi Q
Current biology : CB 2017 May 22;27(10):1498-1505.e6
Current biology : CB 2017 May 22;27(10):1498-1505.e6
Doxorubicin and resveratrol co-delivery nanoparticle to overcome doxorubicin resistance.
Zhao Y, Huan ML, Liu M, Cheng Y, Sun Y, Cui H, Liu DZ, Mei QB, Zhou SY
Scientific reports 2016 Oct 12;6:35267
Scientific reports 2016 Oct 12;6:35267
The role of RhoA in vulvar squamous cell carcinoma: a carcinogenesis, progression, and target therapy marker.
Wang J, Wu Q, Zhang LH, Zhao YX, Wu X
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Mar;37(3):2879-90
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Mar;37(3):2879-90
Dioscin suppresses human laryngeal cancer cells growth via induction of cell-cycle arrest and MAPK-mediated mitochondrial-derived apoptosis and inhibition of tumor invasion.
Si L, Zheng L, Xu L, Yin L, Han X, Qi Y, Xu Y, Wang C, Peng J
European journal of pharmacology 2016 Mar 5;774:105-17
European journal of pharmacology 2016 Mar 5;774:105-17
MicroRNA-505 functions as a tumor suppressor in endometrial cancer by targeting TGF-α.
Chen S, Sun KX, Liu BL, Zong ZH, Zhao Y
Molecular cancer 2016 Feb 2;15:11
Molecular cancer 2016 Feb 2;15:11
Paper-based microreactor array for rapid screening of cell signaling cascades.
Huang CH, Lei KF, Tsang NM
Lab on a chip 2016 Aug 7;16(15):2911-20
Lab on a chip 2016 Aug 7;16(15):2911-20
BMP-6 inhibits cell proliferation by targeting microRNA-192 in breast cancer.
Hu F, Meng X, Tong Q, Liang L, Xiang R, Zhu T, Yang S
Biochimica et biophysica acta 2013 Dec;1832(12):2379-90
Biochimica et biophysica acta 2013 Dec;1832(12):2379-90
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- SKOV-3 cells were subjected to SDS PAGE followed by western blot with 13295-1-AP(CCNA1 antibody) at dilution of 1:500
- Sample type
- cell line
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human testis tissue were subjected to SDS PAGE followed by western blot with 13295-1-AP(CCNA1 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Cyclin A1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Cyclin A1. This antibody recognizes human,mouse,rat antigen. The Cyclin A1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.