Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Flow cytometry [1]
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Validation data
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- Product number
- PAB3835 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB3835, RRID:AB_1571117
- Product name
- BMPR1A polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of BMPR1A.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references BMP2 exposure results in decreased PTEN protein degradation and increased PTEN levels.
Germline mutations in BMPR1A/ALK3 cause a subset of cases of juvenile polyposis syndrome and of Cowden and Bannayan-Riley-Ruvalcaba syndromes.
Chromosomal localization of three human genes encoding bone morphogenetic protein receptors.
Waite KA, Eng C
Human molecular genetics 2003 Mar 15;12(6):679-84
Human molecular genetics 2003 Mar 15;12(6):679-84
Germline mutations in BMPR1A/ALK3 cause a subset of cases of juvenile polyposis syndrome and of Cowden and Bannayan-Riley-Ruvalcaba syndromes.
Zhou XP, Woodford-Richens K, Lehtonen R, Kurose K, Aldred M, Hampel H, Launonen V, Virta S, Pilarski R, Salovaara R, Bodmer WF, Conrad BA, Dunlop M, Hodgson SV, Iwama T, Järvinen H, Kellokumpu I, Kim JC, Leggett B, Markie D, Mecklin JP, Neale K, Phillips R, Piris J, Rozen P, Houlston RS, Aaltonen LA, Tomlinson IP, Eng C
American journal of human genetics 2001 Oct;69(4):704-11
American journal of human genetics 2001 Oct;69(4):704-11
Chromosomal localization of three human genes encoding bone morphogenetic protein receptors.
Aström AK, Jin D, Imamura T, Röijer E, Rosenzweig B, Miyazono K, ten Dijke P, Stenman G
Mammalian genome : official journal of the International Mammalian Genome Society 1999 Mar;10(3):299-302
Mammalian genome : official journal of the International Mammalian Genome Society 1999 Mar;10(3):299-302
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- The BMPR1A polyclonal antibody (Cat # PAB3835) is used in Western blot to detect BMPR1A in mouse muscle tissue lysate (Lane 1) and Hela cell lysate (Lane 2) .
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Flow cytometric analysis of WiDr cells using BMPR1A polyclonal antibody (Cat # PAB3835)(bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
- Validation comment
- Flow Cytometry