ABIN357375

antibody from antibodies-online

Targeting: BMPR1A ACVRLK3, ALK3, CD292

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN357375

Provider

antibodies-online

Product name

anti-Bone Morphogenetic Protein Receptor 1A (BMPR1A) (Middle Region) antibody

Antibody type

Polyclonal

Description

Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Reactivity

Human, Mouse

Host

Rabbit

Epitope

Middle Region

Vial size

0.4 mL

Storage

Store the antibody at 2 - 8°C up to one month or (in aliquots) at -20°C for longer.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

Germline mutations in BMPR1A/ALK3 cause a subset of cases of juvenile polyposis syndrome and of Cowden and Bannayan-Riley-Ruvalcaba syndromes.

Zhou XP, Woodford-Richens K, Lehtonen R, Kurose K, Aldred M, Hampel H, Launonen V, Virta S, Pilarski R, Salovaara R, Bodmer WF, Conrad BA, Dunlop M, Hodgson SV, Iwama T, Järvinen H, Kellokumpu I, Kim JC, Leggett B, Markie D, Mecklin JP, Neale K, Phillips R, Piris J, Rozen P, Houlston RS, Aaltonen LA, Tomlinson IP, Eng C
American journal of human genetics 2001 Oct;69(4):704-11

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Germline mutations of the gene encoding bone morphogenetic protein receptor 1A in juvenile polyposis.

Howe JR, Bair JL, Sayed MG, Anderson ME, Mitros FA, Petersen GM, Velculescu VE, Traverso G, Vogelstein B
Nature genetics 2001 Jun;28(2):184-7

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Activin receptor-like kinases: a novel subclass of cell-surface receptors with predicted serine/threonine kinase activity.

ten Dijke P, Ichijo H, Franzén P, Schulz P, Saras J, Toyoshima H, Heldin CH, Miyazono K
Oncogene 1993 Oct;8(10):2879-87