Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
Reference
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- Product number
- MAB5567 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#MAB5567, RRID:AB_10551483
- Product name
- BCL10 monoclonal antibody, clone 4F8E8H8
- Antibody type
- Monoclonal
- Description
- Mouse monoclonal antibody raised against recombinant BCL10.
- Isotype
- IgG
- Antibody clone number
- 4F8E8H8
- Storage
- Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Card10 is a novel caspase recruitment domain/membrane-associated guanylate kinase family member that interacts with BCL10 and activates NF-kappa B.
Bcl10 and MALT1, independent targets of chromosomal translocation in malt lymphoma, cooperate in a novel NF-kappa B signaling pathway.
Bcl10 is involved in t(1;14)(p22;q32) of MALT B cell lymphoma and mutated in multiple tumor types.
Wang L, Guo Y, Huang WJ, Ke X, Poyet JL, Manji GA, Merriam S, Glucksmann MA, DiStefano PS, Alnemri ES, Bertin J
The Journal of biological chemistry 2001 Jun 15;276(24):21405-9
The Journal of biological chemistry 2001 Jun 15;276(24):21405-9
Bcl10 and MALT1, independent targets of chromosomal translocation in malt lymphoma, cooperate in a novel NF-kappa B signaling pathway.
Lucas PC, Yonezumi M, Inohara N, McAllister-Lucas LM, Abazeed ME, Chen FF, Yamaoka S, Seto M, Nunez G
The Journal of biological chemistry 2001 Jun 1;276(22):19012-9
The Journal of biological chemistry 2001 Jun 1;276(22):19012-9
Bcl10 is involved in t(1;14)(p22;q32) of MALT B cell lymphoma and mutated in multiple tumor types.
Willis TG, Jadayel DM, Du MQ, Peng H, Perry AR, Abdul-Rauf M, Price H, Karran L, Majekodunmi O, Wlodarska I, Pan L, Crook T, Hamoudi R, Isaacson PG, Dyer MJ
Cell 1999 Jan 8;96(1):35-45
Cell 1999 Jan 8;96(1):35-45
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of MCF-7 cell extracts with BCL10 monoclonal antibody, clone 4F8E8H8 (Cat # MAB5567).
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of paraffin-embedded human breast carcinoma (A) and liver carcinoma (B) tissue, showing cytoplasmical localization, using BCL10 monoclonal antibody, clone 4F8E8H8 (Cat # MAB5567) with DAB staining.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)