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ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [5]
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- Product number
- ABIN362289 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Breast Cancer 1 (BRCA1) (pSer988) antibody
- Antibody type
- Polyclonal
- Antigen
- Peptide sequence around phosphorylation site of pSer988 (I-K-S (p) -F-V) derived from Human BRCA1. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
- Description
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- pSer988
- Isotype
- IgG
- Vial size
- 50 μL
- Concentration
- 1 mg/mL
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Submitted references Chk2 phosphorylation of BRCA1 regulates DNA double-strand break repair.
Human Claspin works with BRCA1 to both positively and negatively regulate cell proliferation.
BRCA1 function in T lymphocytes: a cellular specificity of a different kind.
Identification of Id4 as a regulator of BRCA1 expression by using a ribozyme-library-based inverse genomics approach.
BRCA1 mediates ligand-independent transcriptional repression of the estrogen receptor.
Zhang J, Willers H, Feng Z, Ghosh JC, Kim S, Weaver DT, Chung JH, Powell SN, Xia F
Molecular and cellular biology 2004 Jan;24(2):708-18
Molecular and cellular biology 2004 Jan;24(2):708-18
Human Claspin works with BRCA1 to both positively and negatively regulate cell proliferation.
Lin SY, Li K, Stewart GS, Elledge SJ
Proceedings of the National Academy of Sciences of the United States of America 2004 Apr 27;101(17):6484-9
Proceedings of the National Academy of Sciences of the United States of America 2004 Apr 27;101(17):6484-9
BRCA1 function in T lymphocytes: a cellular specificity of a different kind.
Gardner K, Liu ET
Breast cancer research : BCR 2001;3(1):11-3
Breast cancer research : BCR 2001;3(1):11-3
Identification of Id4 as a regulator of BRCA1 expression by using a ribozyme-library-based inverse genomics approach.
Beger C, Pierce LN, Kruger M, Marcusson EG, Robbins JM, Welcsh P, Welch PJ, Welte K, King MC, Barber JR, Wong-Staal F
Proceedings of the National Academy of Sciences of the United States of America 2001 Jan 2;98(1):130-5
Proceedings of the National Academy of Sciences of the United States of America 2001 Jan 2;98(1):130-5
BRCA1 mediates ligand-independent transcriptional repression of the estrogen receptor.
Zheng L, Annab LA, Afshari CA, Lee WH, Boyer TG
Proceedings of the National Academy of Sciences of the United States of America 2001 Aug 14;98(17):9587-92
Proceedings of the National Academy of Sciences of the United States of America 2001 Aug 14;98(17):9587-92
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