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antibody from Invitrogen Antibodies
Targeting: CFTR
ABC35, ABCC7, CF, CFTR/MRP, dJ760C5.1, MRP7, TNR-CFTR
ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Immunocytochemistry [1]
- Other assay [1]
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- Product number
- PA1-935 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- CFTR Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide
- Description
- PA1-935 detects cystic fibrosis transmembrane conductance factor (CFTR) from cells overexpressing the human protein. PA1-935 has been successfully used in immunocytochemistry procedures. Immunocytochemical staining of HEK293 cells overexpressing human CFTR with this antibody results in staining primarily of the plasma membrane. PA1-935 immunizing peptide corresponds to amino acid residues 103-117 from human CFTR protein. This sequence is completely conserved between human, rabbit, and monkey and there is a one amino acid substitution in rat, bovine, and sheep.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100 µg
- Concentration
- 1 mg/mL
- Storage
- -20° C, Avoid Freeze/Thaw Cycles
Submitted references Incomplete reprogramming after fusion of human multipotent stromal cells and bronchial epithelial cells.
Annexin A5 increases the cell surface expression and the chloride channel function of the DeltaF508-cystic fibrosis transmembrane regulator.
Disruption of CFTR-dependent lipid rafts reduces bacterial levels and corneal disease in a murine model of Pseudomonas aeruginosa keratitis.
Antibodies for CFTR studies.
Production and characterisation of monoclonal and polyclonal antibodies to different regions of the cystic fibrosis transmembrane conductance regulator (CFTR): detection of immunologically related proteins.
Curril IM, Koide M, Yang CH, Segal A, Wellman GC, Spees JL
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010 Dec;24(12):4856-64
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010 Dec;24(12):4856-64
Annexin A5 increases the cell surface expression and the chloride channel function of the DeltaF508-cystic fibrosis transmembrane regulator.
Le Drévo MA, Benz N, Kerbiriou M, Giroux-Metges MA, Pennec JP, Trouvé P, Férec C
Biochimica et biophysica acta 2008 Oct;1782(10):605-14
Biochimica et biophysica acta 2008 Oct;1782(10):605-14
Disruption of CFTR-dependent lipid rafts reduces bacterial levels and corneal disease in a murine model of Pseudomonas aeruginosa keratitis.
Zaidi T, Bajmoczi M, Zaidi T, Golan DE, Pier GB
Investigative ophthalmology & visual science 2008 Mar;49(3):1000-9
Investigative ophthalmology & visual science 2008 Mar;49(3):1000-9
Antibodies for CFTR studies.
Mendes F, Farinha CM, Roxo-Rosa M, Fanen P, Edelman A, Dormer R, McPherson M, Davidson H, Puchelle E, De Jonge H, Heda GD, Gentzsch M, Lukacs G, Penque D, Amaral MD
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society 2004 Aug;3 Suppl 2:69-72
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society 2004 Aug;3 Suppl 2:69-72
Production and characterisation of monoclonal and polyclonal antibodies to different regions of the cystic fibrosis transmembrane conductance regulator (CFTR): detection of immunologically related proteins.
Walker J, Watson J, Holmes C, Edelman A, Banting G
Journal of cell science 1995 Jun;108 ( Pt 6):2433-44
Journal of cell science 1995 Jun;108 ( Pt 6):2433-44
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunolocalization of CFTR in HEK293 cells stably transfected with the CFTR gene.
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- NULL
