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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [4]
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- Validations
- Immunohistochemistry [1]
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- Product number
- HPA020934 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA020934, RRID:AB_1845118
- Product name
- Anti-ASS1
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human ASS1, Gene description: argininosuccinate synthase 1, Alternative Gene Names: ASS, CTLN1, Validated applications: IHC, ICC, WB, Uniprot ID: P00966, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.1 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references BAP1 Loss Is Associated with Higher ASS1 Expression in Epithelioid Mesothelioma: Implications for Therapeutic Stratification
Characterisation of Expression the Arginine Pathway Enzymes in Childhood Brain Tumours to Determine Susceptibility to Therapeutic Arginine Depletion
Arginine Depletion Therapy with ADI-PEG20 Limits Tumor Growth in Argininosuccinate Synthase–Deficient Ovarian Cancer, Including Small-Cell Carcinoma of the Ovary, Hypercalcemic Type
Inhibition of the Polyamine Synthesis Pathway Is Synthetically Lethal with Loss of Argininosuccinate Synthase 1
Barnett S, Kenyani J, Tripari M, Butt Z, Grosman R, Querques F, Shaw L, Silva L, Goate Z, Marciniak S, Rassl D, Jackson R, Lian L, Szlosarek P, Sacco J, Coulson J
Molecular Cancer Research 2023;21(5):411-427
Molecular Cancer Research 2023;21(5):411-427
Characterisation of Expression the Arginine Pathway Enzymes in Childhood Brain Tumours to Determine Susceptibility to Therapeutic Arginine Depletion
Bishop E, Dimitrova M, Froggatt A, Estevez-Cebrero M, Storer L, Mussai F, Paine S, Grundy R, Dandapani M, Prodam F
BioMed Research International 2022;2022(1)
BioMed Research International 2022;2022(1)
Arginine Depletion Therapy with ADI-PEG20 Limits Tumor Growth in Argininosuccinate Synthase–Deficient Ovarian Cancer, Including Small-Cell Carcinoma of the Ovary, Hypercalcemic Type
Ji J, Cochrane D, Tessier-Cloutier B, Chen S, Ho G, Pathak K, Alcazar I, Farnell D, Leung S, Cheng A, Chow C, Colborne S, Negri G, Kommoss F, Karnezis A, Morin G, McAlpine J, Gilks C, Weissman B, Trent J, Hoang L, Pirrotte P, Wang Y, Huntsman D
Clinical Cancer Research 2020;26(16):4402-4413
Clinical Cancer Research 2020;26(16):4402-4413
Inhibition of the Polyamine Synthesis Pathway Is Synthetically Lethal with Loss of Argininosuccinate Synthase 1
Locke M, Ghazaly E, Freitas M, Mitsinga M, Lattanzio L, Lo Nigro C, Nagano A, Wang J, Chelala C, Szlosarek P, Martin S
Cell Reports 2016;16(6):1604-1613
Cell Reports 2016;16(6):1604-1613
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human kidney and lymph node tissues using HPA020934 antibody. Corresponding ASS1 RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol
