Explore
Validate
Learn
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 21857-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- SAFB antibody
- Antibody type
- Polyclonal
- Description
- SAFB antibody (Cat. #21857-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Discovery of Thermal Sensitizers That Inhibit Heat-Induced SAFB Granule Formation.
SAFB restricts contact domain boundaries associated with L1 chimeric transcription.
Stress-induced TDP-43 nuclear condensation causes splicing loss of function and STMN2 depletion.
ALS-linked cytoplasmic FUS assemblies are compositionally different from physiological stress granules and sequester hnRNPA3, a novel modifier of FUS toxicity.
RBM45 associates with nuclear stress bodies and forms nuclear inclusions during chronic cellular stress and in neurodegenerative diseases.
Furutani Y, Shimasaki N, Yamada R, Ohtsuki T, Watanabe K
Journal of medicinal chemistry 2026 Mar 12;69(5):5944-5955
Journal of medicinal chemistry 2026 Mar 12;69(5):5944-5955
SAFB restricts contact domain boundaries associated with L1 chimeric transcription.
Hong Y, Bie L, Zhang T, Yan X, Jin G, Chen Z, Wang Y, Li X, Pei G, Zhang Y, Hong Y, Gong L, Li P, Xie W, Zhu Y, Shen X, Liu N
Molecular cell 2024 May 2;84(9):1637-1650.e10
Molecular cell 2024 May 2;84(9):1637-1650.e10
Stress-induced TDP-43 nuclear condensation causes splicing loss of function and STMN2 depletion.
Huang WP, Ellis BCS, Hodgson RE, Sanchez Avila A, Kumar V, Rayment J, Moll T, Shelkovnikova TA
Cell reports 2024 Jul 23;43(7):114421
Cell reports 2024 Jul 23;43(7):114421
ALS-linked cytoplasmic FUS assemblies are compositionally different from physiological stress granules and sequester hnRNPA3, a novel modifier of FUS toxicity.
An H, Litscher G, Watanabe N, Wei W, Hashimoto T, Iwatsubo T, Buchman VL, Shelkovnikova TA
Neurobiology of disease 2022 Jan;162:105585
Neurobiology of disease 2022 Jan;162:105585
RBM45 associates with nuclear stress bodies and forms nuclear inclusions during chronic cellular stress and in neurodegenerative diseases.
Collins M, Li Y, Bowser R
Acta neuropathologica communications 2020 Jun 26;8(1):91
Acta neuropathologica communications 2020 Jun 26;8(1):91
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- MCF-7 cells were subjected to SDS PAGE followed by western blot with 21857-1-AP( SAFB Antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The SAFB antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human SAFB. This antibody recognizes human antigen. The SAFB antibody has been validated for the following applications: ELISA, IHC, WB analysis.
