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- Product number
- ABIN394374 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Scaffold Attachment Factor B (SAFB) (AA 111-201) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 111-201
- Isotype
- IgG
- Antibody clone number
- 5A11
- Vial size
- 100 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references Low SAFB levels are associated with worse outcome in breast cancer patients.
SAFB1 mediates repression of immune regulators and apoptotic genes in breast cancer cells.
The enzymatic activity of SR protein kinases 1 and 1a is negatively affected by interaction with scaffold attachment factors B1 and 2.
Estradiol and tamoxifen mediate rescue of the dominant-negative effects of estrogen response element-binding protein in vivo and in vitro.
Defining the human deubiquitinating enzyme interaction landscape.
Hammerich-Hille S, Bardout VJ, Hilsenbeck SG, Osborne CK, Oesterreich S
Breast cancer research and treatment 2010 Jun;121(2):503-9
Breast cancer research and treatment 2010 Jun;121(2):503-9
SAFB1 mediates repression of immune regulators and apoptotic genes in breast cancer cells.
Hammerich-Hille S, Kaipparettu BA, Tsimelzon A, Creighton CJ, Jiang S, Polo JM, Melnick A, Meyer R, Oesterreich S
The Journal of biological chemistry 2010 Feb 5;285(6):3608-16
The Journal of biological chemistry 2010 Feb 5;285(6):3608-16
The enzymatic activity of SR protein kinases 1 and 1a is negatively affected by interaction with scaffold attachment factors B1 and 2.
Tsianou D, Nikolakaki E, Tzitzira A, Bonanou S, Giannakouros T, Georgatsou E
The FEBS journal 2009 Sep;276(18):5212-27
The FEBS journal 2009 Sep;276(18):5212-27
Estradiol and tamoxifen mediate rescue of the dominant-negative effects of estrogen response element-binding protein in vivo and in vitro.
Chen H, Clemens TL, Hewison M, Adams JS
Endocrinology 2009 May;150(5):2429-35
Endocrinology 2009 May;150(5):2429-35
Defining the human deubiquitinating enzyme interaction landscape.
Sowa ME, Bennett EJ, Gygi SP, Harper JW
Cell 2009 Jul 23;138(2):389-403
Cell 2009 Jul 23;138(2):389-403
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Supportive validation
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