FNab04479

antibody from FineTest Biotech

Targeting: KCNAB2 AKR6A5, HKvbeta2.1, HKvbeta2.2, KCNA2B

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Antibody Data

Product number

FNab04479

Provider

FineTest Biotech

Product name

KCNAB2 antibody

Antibody type

Polyclonal

Antigen

Recombinant protein fragment

Description

Cytoplasmic potassium channel subunit that modulates the characteristics of the channel-forming alpha-subunits(PubMed:7649300, PubMed:11825900). Contributes to the regulation of nerve signaling, and prevents neuronal hyperexcitability(By similarity). Promotes expression of the pore-forming alpha subunits at the cell membrane, and thereby increases channel activity(By similarity). Promotes potassium channel closure via a mechanism that does not involve physical obstruction of the channel pore(PubMed:7649300, PubMed:11825900). Promotes KCNA4 channel closure(PubMed:7649300, PubMed:11825900). Modulates the functional properties of KCNA5(By similarity). Enhances KCNB2 channel activity(By similarity). Binds NADPH and has NADPH-dependent aldoketoreductase activity(By similarity). Has broad substrate specificity and can catalyze the reduction of methylglyoxal, 9,10-phenanthrenequinone, prostaglandin J2, 4-nitrobenzaldehyde, 4-nitroacetophenone and 4-oxo-trans-2-nonenal(in vitro)(By similarity).

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Antigen sequence

potassium voltage-gated channel, sh
aker-related subfamily, beta member
2


Epitope

IgG

Isotype

IgG

Vial size

100¦Ìg

Concentration

Immunogen affinity purified

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

Handling

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)