Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- PB9649 - Provider product page
- Provider
- Boster Biological Technology
- Product name
- Anti-Kv1.2/KCNA2 Antibody Picoband™
- Antibody type
- Polyclonal
- Description
- Polyclonal antibody for KV1.2/KCNA2 detection. Host: Rabbit.Size: 100μg/vial. Tested applications: WB, ICC/IF, FCM. Reactive species: Human;Mouse;Rat. KV1.2/KCNA2 information: Molecular Weight: 56717 MW; Subcellular Localization: Cell membrane ; Multi- pass membrane protein . Membrane . Cell projection, axon . Cell junction, synapse . Endoplasmic reticulum membrane . Cell projection, lamellipodium membrane . Cell junction, synapse, synaptosome . Cell junction, synapse, presynaptic cell membrane . Cell projection, dendrite . KCNA2 by itself is detected both at the endoplasmic reticulum and at the cell membrane. Coexpression with KCNA4 or with beta subunits promotes expression at the cell membrane. Coexpression with KCNA1 inhibits cell surface expression; Tissue Specificity: Detected in brain cortex (PubMed:16473933). Detected in peroneal nerve in the juxtaparanodal regions of the node of Ranvier; expression is decreased in patients with diabetes mellitus that suffer from axonal neuropathy (PubMed:22649228). Detected in paranodal and juxtanodal zones in myelinated spinal cord (at protein level) (PubMed:11086297).
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Vial size
- 100μg/vial
- Concentration
- Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
- Storage
- At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquoted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
- Handling
- Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
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Supportive validation
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- Boster Biological Technology (provider)
- Main image
- Experimental details
- Anti- Kv1.2 Picoband antibody, PB9649, Western blottingAll lanes: Anti Kv1.2 (PB9649) at 0.5ug/ml Lane 1: Rat Kidney Tissue Lysate at 50ug Lane 2: Rat Brain Tissue Lysate at 50ug Lane 3: Mouse Brain Tissue Lysate at 50ug Lane 4: Mouse Kidney Tissue Lysate at 50ug Predicted bind size: 57KD Observed bind size: 57KD
- Additional image