CABT-B10491

antibody from Creative Diagnostics

Targeting: KCNA2 HK4, Kv1.2

Western blot (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

CABT-B10491

Provider

Creative Diagnostics

Product name

Mouse anti-Rat Kcna2 monoclonal antibody, clone T25-27

Antibody type

Monoclonal

Description

Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential. The coding region of this gene is intronless, and the gene is clustered with genes KCNA3 and KCNA10 on chromosome 1. [provided by RefSeq, Jul 2008]

Reactivity

Rat

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

T25-27

Storage

Store at -20°C.Aliquot to avoid repeated freezing and thawing.