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- Antigen structure
- References [315]
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- Product number
- 14418-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14418-1-AP, RRID:AB_2227873
- Product name
- ATP1A1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ATP1A1 antibody (Cat. #14418-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 150ul
Submitted references Mitochondria serve as a source of mineral precursors initiating early cartilage calcification in osteoarthritis.
Esflurbiprofen exerts a fast-onset antidepressant effect by blocking SERT-nNOS interaction.
Alpha-Fetoprotein Stimulates Cleavage of Membranal MICA/B on Liver Cancer Cell Lead to Escape Immune Surveillance of Natural Killer Cells.
In Vitro Evaluation of Cadmium-Induced Phosphate Reabsorption Impairment.
FAK/SRC-JNK axis promotes ferroptosis via upregulating ACSL4 expression.
Membrane-camouflaged nanoparticle alleviates intervertebral disc degeneration via oxidative stress suppression and autophagy activation.
Teleost GSDMEc regulates GSDMEa-mediated pyroptosis.
LRRC8A Mediates Ischemic Neuronal Injury by Potentiating NMDA Receptor Activity and Activating Mitochondrial Apoptotic Pathway.
The USP1-WDR48 deubiquitinase complex functions as a molecular switch regulating tumor-associated macrophage activation and anti-tumor response.
Tuina Inhibits Synaptic Plasticity Through the Astrocytic NDRG2/GLT-1 Pathway to Alleviate Neuropathic Pain.
Downregulation of BST2 Rescues Cochlear Nerve Demyelination in Age-Related Hearing Loss via Enhancing Schwann Cell Migration.
The allyl isothiocyanate (AITC) isolated from mustard (Sinapis alba L.) oil exerts antidepressant effects by blocking the interaction between SERT and nNOS.
Hybrid macrophage-mitochondria extracellular vesicles for mitochondrial ROS regulation in diabetic wounds.
Psoralen Promotes Direct Chemical Reprogramming of Mouse Embryonic Fibroblasts into Osteoblast-like Cells.
Claudin18.2 promote gastric cancer proliferation by activating MCM2/5.
Synergistic mechanical and therapeutic modulation of engineered tumor cell-derived microparticles for enhanced cancer treatment.
Targeting SLC5A2 suppresses colorectal tumour development by enhancing NK cell activity through extracellular vesicle-dependent MICA/B signalling.
Extracellular Vesicle-Mediated Nucleolin Transfer in Glioblastoma: A Targetable Axis Driving Blood-Tumour Barrier Formation.
ATP1A1 enhances porcine reproductive and respiratory syndrome virus type 2 attachment and internalization.
Macrophage-Targeted Nanocarriers Based on Tetrahedral DNA Nanostructure Alleviate Sepsis-Induced Acute Lung Injury by Triple-Pathway Suppression of Pyroptosis.
EVA1A Regulates Hepatic Lipid Homeostasis by Modulating CD36 Expression and Its Palmitoylation.
Na(+)/K(+)-ATPase Modulates Purinergic P2X3 Receptor Function to Drive Bone Cancer Pain.
Role of VDAC1 in hepatocyte apoptosis during acute liver injury in rats induced by obstructive jaundice.
G Protein-Coupled Receptor 30 Attenuates Neuronal Pyroptosis Induced by Subarachnoid Hemorrhage.
NCAPG promotes the malignant progression of endometrioid cancer through LEF1/SEMA7A/PI3K-AKT.
Unveiling ammonia-induced cell death: a new frontier in clear cell renal cell carcinoma prognosis.
Impact of the ENPP1 mutation on bone mineralization and ectopic calcification: evidence from in vitro and in vivo models.
ZDHHC14 and APT2 regulate the palmitoylation of HSV-2 gB.
LncDARS-AS1 Regulates ATP1A1 Stability and Enhances Na(+)/K(+) ATPase Activity to Promote Osteosarcoma Metastasis.
Adiponectin pathway regulates cerebral metabolic dysfunction and neuroinflammation via the AdipoR1/PI3K/Akt axis in Perioperative Neurocognitive Disorder.
Metformin alleviates hyperkalemia-induced arrhythmia and cardiac injury in mice through decreasing SK2 and intracellular Ca(2).
Na+,K+-ATPase α isoforms in sperm show a highly structured and distinct pattern of distribution.
Role of Extracellular Histidine Residues for the Function and pH Sensitivity of Human Organic Anion Transporting Polypeptide 1B3.
GRK2-mediated phosphorylation and de-succinylation of PKM2 reduce macrophage glycolysis in rheumatoid arthritis.
USP47 Regulates Excitatory Synaptic Plasticity and Modulates Seizures in Murine Models by Blocking Ubiquitinated AMPAR Degradation.
Astragaloside IV-PESV facilitates pyroptosis by enhancing palmitoylation of GSDMD protein mediated by ZDHHC1.
DEPTOR suppresses lymphomagenesis by promoting EGFR degradation via HUWE1 E3 ligase.
Elevated Release of Presynaptic Glutamate: The Potential Pathogenesis of Anti-NMDAR Encephalitis-Associated Seizures.
Nebulized Inhalation of Engineered Extracellular Vesicles to Destruct Pre-metastatic Niche and Inhibit Postoperative Lung Metastasis in a Mouse Model.
Microtubule-dependent regulation of TMEM16A-mediated Ca(2+)-activated Cl(-) currents in vascular smooth muscle cells.
ApoE is Secreted as a Lipid Nanoparticle by Mammalian Cells: Implications for Alzheimer's Disease Pathogenesis.
Rab26 promotes hypoxia-induced hyperproliferation of PASMCs by modulating the AT1R-STAT3-YAP axis.
NLRP3 Inflammasome Activation Contributes to Seizure Susceptibility in Anti-NMDAR Encephalitis: Evidence from Patients and a Mouse Model.
Levofloxacin-induced seizure susceptibility involves both enhanced glutamatergic and impaired GABAergic synaptic function.
PCSK9 promotes progression of anaplastic thyroid cancer through E-cadherin endocytosis.
Rab11a-dependent recycling of Glut3 inhibits seizure-induced neuronal disulfidptosis by alleviating glucose deficiency.
Restoring Autophagy by Exercise Ameliorates Insulin Resistance Partly via Calcineurin-Driven TFEB Nuclear Translocation.
Micropeptide hSPAR regulates glutamine levels and suppresses mammary tumor growth via a TRIM21-P27KIP1-mTOR axis.
The essential role of sphingolipids in TRPC5 ion channel localization and functionality within lipid rafts.
A subcellular map of translational machinery composition and regulation at the single-molecule level.
Pathogenic germline variants in Chinese pancreatic adenocarcinoma patients.
PTPN23-dependent activation of PI3KC2α is a therapeutic vulnerability of BRAF-mutant cancers.
The Frmpd3 Protein Regulates Susceptibility to Epilepsy by Combining with GRIP and GluA2.
Target Identification of Marine Natural Product Odoamide:Odoamide Induces Apoptotic Cell Death by Targeting ATPase Na(+)/K(+) Transporting Subunit Alpha 1 (ATP1A1).
The wheat stripe rust effector PstEXLX1 inhibits formate dehydrogenase activity to suppress immunity in wheat.
Functional characteristics of equilibrative nucleoside transporter 2 (ENT2/SLC29A2) for the transport of urate as a newly identified substrate.
Alpha-synuclein Fibrils Inhibit Activation of the BDNF/ERK Signaling Loop in the mPFC to Induce Parkinson's Disease-like Alterations with Depression.
Leucyl-tRNA synthetase regulates casein synthesis in dairy cows via the mTORC1-LAT1 pathway.
Membrane biomimetic nanoenzyme-incorporated hybrid glycyrrhizic acid hydrogel for precise mitochondrial ROS scavenging for osteoarthritis treatment.
K(+)-H(+) coupling strategy for immune regulation and bone defect repair.
AMPK phosphorylation of K(Ca)2.3 alleviates angiotensin II-induced endothelial dysfunction.
Extracellular HSP90-Facilitated Degradation of Extracellular and Membrane Proteins by Bifunctional Small Molecules.
PARP inhibition elicits NK cell-associated immune evasion via potentiating HLA-G expression in tumor.
Macrophage-mimetic liposomes co-delivering ceria and Ac2-26 peptide for penumbra protection in ischemic stroke.
Genetically engineered chondrocyte-mimetic nanoplatform attenuates osteoarthritis by blocking IL-1β and restoring sirtuin-3.
Preparation, Characterization, and Functional Evaluation of a Novel Recombinant Hypoglycemic Protein with Multifunctional Effects.
Electrically Driven Chimeric Extracellular Vesicles Crossing the Fundus Barrier for Retinoblastoma Treatment.
AF6 regulates intestinal IgA via crosstalk between intestinal epithelial cells and immune cells in inflammatory bowel disease.
CLDN4 palmitoylation promotes hepatic-to-biliary lineage transition and lenvatinib resistance in hepatocellular carcinoma.
K542 acetylation promotes YTHDF2 binding to m6A-modified mRNAs and fosters colorectal cancer progression.
Programmed cell death-related gene IL20RA facilitates tumor progression and remodels tumor microenvironment in thyroid cancer.
MYO1F positions cGAS on the plasma membrane to ensure full and functional signaling.
The cystogenic effects of ouabain in autosomal dominant polycystic kidney disease require cell caveolae.
Aspartate signalling drives lung metastasis via alternative translation.
AFP shields hepatocellular carcinoma from macrophage phagocytosis by regulating HuR-mediated CD47 translocation in cellular membrane.
VANGL2 alleviates inflammatory bowel disease by recruiting the ubiquitin ligase MARCH8 to limit NLRP3 inflammasome activation through OPTN-mediated selective autophagy.
High-resolution spatially resolved proteomics of complex tissues based on microfluidics and transfer learning.
A Granzyme B-Cleavable T Cell-Targeted Bispecific Cell Vesicle Connector for Reversing New-Onset Type 1 Diabetes.
Alpha4 Na,K-ATPase Localization and Expression Are Dynamic Aspects of Spermatogenesis and in Sperm Incubated Under Capacitating Conditions.
The sperm specific Na (+) ,K (+) -ATPase α4 shows a highly structured and dynamic distribution at the sperm flagellum.
G-protein coupled receptor kinase 2 mediates rheumatoid arthritis-induced depression-like behaviors via the hippocampal CRHR1 signaling pathway.
Sigma1 inhibitor suppression of adaptive immune resistance mechanisms mediated by cancer cell derived extracellular vesicles.
Norepinephrine Induces Sertoli Cell Ferroptosis via Receptors Desensitization Causing Stress-Related Male Reproductive Dysfunction.
Vinburnine Sensitizes Radiotherapy Efficacy in Nasopharyngeal Carcinoma by Triggering Pyroptosis and Immune Responses via Activation of EDAR-NFκB Pathway.
Semenogelin I-derived peptide SgI-52 binds membrane Peroxiredoxin 6 and induces oxidative stress in asthenozoospermic sperm.
Membrane dome-based regulation mechanism of the mechanosensitive PIEZO channel.
Sestrin 2 Regulates Milk Protein Synthesis through a LAT1/mTOR Pathway.
Pathogenic Mechanism of the KCNQ4 Gene Variant in Hearing Loss and Functional Validation in a Zebrafish Model.
The fatty acid receptor CD36 promotes macrophage infiltration via p110γ signaling to stimulate metastasis.
P5CS deacetylation mediated by SIRT2 facilitates tumor growth by enhancing mitochondrial respiration in hepatocellular carcinoma.
Molecular mechanism for the interaction of MOG1 with the intracellular loop II of cardiac sodium channel Na(v)1.5 and its role in arrhythmias.
The role of FLVCR1 and FLVCR2 in choline transport in the Caco-2 intestinal epithelial cell model and rat small intestine.
LAPTM5 confers cisplatin resistance in NSCLC by suppressing LAMP1 ubiquitination to stabilize lysosomal membranes and sustain autophagic flux.
Cardiopulmonary Bypass-Induced IL-17A Aggravates Caspase-12-Dependent Neuronal Apoptosis Through the Act1-IRE1-JNK1 Pathway.
Biomimetic magnetobacterial microrobots for active pneumonia therapy.
Effects of Cholesterol Metabolism on Corneal Endothelial Dysfunction in Patients With Type 1 Diabetes.
Neutrophil-like cell membrane-coated metal-organic frameworks for siRNA delivery targeting NOX4 to alleviate oxidative stress in acute ischemic injury.
MLKL activity requires a splicing-regulated, druggable intramolecular interaction.
HSP105 inhibition downregulates store-operated calcium entry and promotes acute UVB-induced tight junction disruption.
Intercellular adhesion molecule-1 suppresses TMZ chemosensitivity in acquired TMZ-resistant gliomas by increasing assembly of ABCB1 on the membrane.
Biomimetic nanomedicine cocktail enables selective cell targeting to enhance ovarian Cancer chemo- and immunotherapy.
Inhibition of GSK3α,β rescues cognitive phenotypes in a preclinical mouse model of CTNNB1 syndrome.
Novel Dual PPAR δ/γ Partial Agonist Induces Hepatic Lipid Accumulation through Direct Binding and Inhibition of AKT1 Phosphorylation, Mediating CD36 Upregulation.
Deficiency of geranylgeranyl biphosphate synthase in kidney tubules causes cystic kidney disease.
TMC7 deficiency causes acrosome biogenesis defects and male infertility in mice.
Scavenger Receptor Class B Type I Modulates Epileptic Seizures and Receptor α2δ-1 Expression.
Nrf2 deficiency exacerbated pulmonary pyroptosis in maternal hypoxia-induced intrauterine growth restriction offspring mice.
Astrocyte-derived lactoferrin inhibits neuronal ferroptosis by reducing iron content and GPX4 degradation in APP/PS1 transgenic mice.
Structural insights into the mechanisms of urea permeation and distinct inhibition modes of urea transporters.
Hepatocyte-derived Fetuin-A promotes alcohol-associated liver disease in mice by inhibiting autophagy-lysosome degradation of TLR and M2 macrophage polarization.
Stevioside Ameliorates Palmitic Acid-Induced Abnormal Glucose Uptake via the PDK4/AMPK/TBC1D1 Pathway in C2C12 Myotubes.
p53 suppresses the inflammatory response following respiratory syncytial virus infection by inhibiting TLR2.
Ultrasound Imaging of Tumor Vascular CD93 with MMRN2 Modified Microbubbles for Immune Microenvironment Prediction.
Targeting osteopontin alleviates endometriosis and inflammation by inhibiting the RhoA/ROS axis and achieves non-invasive in vitro detection via menstrual blood.
Knockdown of trem2 promotes proinflammatory microglia and inhibits glioma progression via the JAK2/STAT3 and NF-κB pathways.
6-Gingerol alleviates ectopic lipid deposition in skeletal muscle by regulating CD36 translocation and mitochondrial function.
PEBP4 deficiency aggravates LPS-induced acute lung injury and alveolar fluid clearance impairment via modulating PI3K/AKT signaling pathway.
Disruption of the Na(+)/K(+)-ATPase-purinergic P2X7 receptor complex in microglia promotes stress-induced anxiety.
SCN5A-L256del and L1621F exhibit loss-of-function properties related to autosomal recessive congenital cardiac disorders presenting as sick sinus syndrome, dilated cardiomyopathy, and sudden cardiac death.
Neutrophil-derived nanovesicles deliver IL-37 to mitigate renal ischemia-reperfusion injury via endothelial cell targeting.
Signature identification based on immunogenic cell death-related lncRNAs to predict the prognosis and immune activity of patients with endometrial carcinoma.
Impact of RAAS Receptors and Membrane-Bound Transporter System in the Left Ventricle during the Long-Term Control of Hypertension.
Homeostatic coordination of cellular phosphate uptake and efflux requires an organelle-based receptor for the inositol pyrophosphate IP8.
Acetylation of ELMO1 correlates with Rac1 activity and colorectal cancer progress.
Noncoding RNA regulates the expression of Krm1 and Dkk2 to synergistically affect aortic valve lesions.
Membranal Expression of Calreticulin Induced by Unfolded Protein Response in Melanocytes: A Mechanism Underlying Oxidative Stress-Induced Autoimmunity in Vitiligo.
Ultrasound-responsive Bi(2)MoO(6)-MXene heterojunction as ferroptosis inducers for stimulating immunogenic cell death against ovarian cancer.
Human Kidney Proximal Tubule-Microvascular Model Facilitates High-Throughput Analyses of Structural and Functional Effects of Ischemia-Reperfusion Injury.
Hyaluronan delays human amniotic epithelial stem cell senescence by regulating CD44 isoform switch to activate AKT/mTOR signals.
Biomimetic Nanomedicine Targeting Orchestrated Metabolism Coupled with Regulatory Factors to Disrupt the Metabolic Plasticity of Breast Cancer.
Deleting IP6K1 stabilizes neuronal sodium-potassium pumps and suppresses excitability.
Optimization of Cell Membrane Purification for the Preparation and Characterization of Cell Membrane Liposomes.
Targeting overexpressed antigens in glioblastoma via CAR T cells with computationally designed high-affinity protein binders.
Annexin-A1 tripeptide enhances functional recovery and mitigates brain damage in traumatic brain injury by inhibiting neuroinflammation and preventing ANXA1 nuclear translocation in mice.
A Homozygous Variant in NAA60 Is Associated with Primary Familial Brain Calcification.
SEMA7A-mediated juxtacrine stimulation of IGFBP-3 upregulates IL-17RB at pancreatic cancer invasive front.
Melanocortin 1 receptor mediates melanin production by interacting with the BBSome in primary cilia.
Febuxostat enhances the efficacy of dasatinib by inhibiting ATP-binding cassette subfamily G member 2 (ABCG2) in chronic myeloid leukemia cells.
Artemisitene induces apoptosis of breast cancer cells by targeting FDFT1 and inhibits the growth of breast cancer patient-derived organoids.
Dual-Functional Nanodroplet for Tumor Vasculature Ultrasound Imaging and Tumor Immunosuppressive Microenvironment Remodeling.
Subcellular Proteomic Mapping of Lysine Lactylation.
GPR37-enhanced ubiquitination of ATP1A1 inhibits tumor progression and radiation resistance in esophageal squamous cell carcinoma.
The classical D1 dopamine receptor antagonist SCH23390 is a functional sigma-1 receptor allosteric modulator.
ATG5-mediated keratinocyte ferroptosis promotes M1 polarization of macrophages to aggravate UVB-induced skin inflammation.
Cancer cell membrane-camouflaged paclitaxel/PLGA nanoparticles for targeted therapy against lung cancer.
Postsynaptic lncRNA Sera/Pkm2 pathway orchestrates the transition from social competition to rank by remodeling the neural ensemble in mPFC.
Extract of Phyllanthus emblica L. fruit stimulates basal glucose uptake and ameliorates palmitate-induced insulin resistance through AMPK activation in C2C12 myotubes.
Therapeutic application of extracellular vesicular EGFR isoform D as a co-drug to target squamous cell cancers with tyrosine kinase inhibitors.
Membranous translocation of murine double minute 2 promotes the increased renal tubular immunogenicity in ischemia-reperfusion-induced acute kidney injury.
GDNF improves the cognitive ability of PD mice by promoting glycosylation and membrane distribution of DAT.
The Lipophilic Extract from Ginkgo biloba L. Leaves Promotes Glucose Uptake and Alleviates Palmitate-Induced Insulin Resistance in C2C12 Myotubes.
K48-linked deubiquitination of VGLL4 by USP15 enhances the efficacy of tumor immunotherapy in triple-negative breast cancer.
CAV3 alleviates diabetic cardiomyopathy via inhibiting NDUFA10-mediated mitochondrial dysfunction.
Nerve Growth Factor/Tyrosine Kinase A Receptor Pathway Enhances Analgesia in an Experimental Mouse Model of Bone Cancer Pain by Increasing Membrane Levels of δ-Opioid Receptors.
Effects of frog skin peptide temporin-1CEa and its analogs on ox-LDL induced macrophage-derived foam cells.
WT1(+) glomerular parietal epithelial progenitors promote renal proximal tubule regeneration after severe acute kidney injury.
Stiff matrix induced srGAP2 tension gradients control migration direction in triple-negative breast cancer.
Telaprevir Improves Memory and Cognition in Mice Suffering Ischemic Stroke via Targeting MALT1-Mediated Calcium Overload and Necroptosis.
HSP90B1-mediated plasma membrane localization of GLUT1 promotes radioresistance of glioblastomas.
FAT4 overexpression promotes antitumor immunity by regulating the β-catenin/STT3/PD-L1 axis in cervical cancer.
Liang-Ge-San inhibits dengue virus serotype 2 infection by reducing caveolin1-induced cytoplasmic heat shock protein 70 translocation into the plasma membrane.
Neuroplastin exerts antiepileptic effects through binding to the α1 subunit of GABA type A receptors to inhibit the internalization of the receptors.
STIM2 regulates NMDA receptor endocytosis that is induced by short-term NMDA receptor overactivation in cortical neurons.
Meta-data analysis of kidney stone disease highlights ATP1A1 involvement in renal crystal formation.
Cell membrane derived liposomes loaded with DNase I target neutrophil extracellular traps which inhibits colorectal cancer liver metastases.
Novel secreted STPKLRR from Vibrio splendidus AJ01 promotes pathogen internalization via mediating tropomodulin phosphorylation dependent cytoskeleton rearrangement.
The Bacillus cereus toxin alveolysin disrupts the intestinal epithelial barrier by inducing microtubule disorganization through CFAP100.
The Weakened Interaction Between HECTD4 and GluN2B in Ischemic Stroke Promotes Calcium Overload and Brain Injury Through a Mechanism Involving the Decrease of GluN2B and MALT1 Ubiquitination.
Lysosomal control of senescence and inflammation through cholesterol partitioning.
Activation of metabotropic glutamate receptor 1 regulates hippocampal CA1 region excitability in rats with status epilepticus by suppressing the HCN1 channel.
Identification of a novel missense SCN5A mutation in a Chinese Han family with Brugada syndrome.
Role of the Peli1-RIPK1 Signaling Axis in Methamphetamine-Induced Neuroinflammation.
25-hydroxycholesterol inhibits human papillomavirus infection in cervical epithelial cells by perturbing cytoskeletal remodeling.
Activation of TLR7-mediated autophagy increases epileptic susceptibility via reduced KIF5A-dependent GABA(A) receptor transport in a murine model.
ICP4-Associated Activation of Rap1b Facilitates Herpes Simplex Virus Type I (HSV-1) Infection in Human Corneal Epithelial Cells.
ZDHHC2-Mediated AGK Palmitoylation Activates AKT-mTOR Signaling to Reduce Sunitinib Sensitivity in Renal Cell Carcinoma.
Ultrasound Responsive Nanovaccine Armed with Engineered Cancer Cell Membrane and RNA to Prevent Foreseeable Metastasis.
Coreceptor AXL Facilitates African Swine Fever Virus Entry via Apoptotic Mimicry.
Melatonin inhibits ferroptosis and delays age-related cataract by regulating SIRT6/p-Nrf2/GPX4 and SIRT6/NCOA4/FTH1 pathways.
Tilianin improves lipid profile and alleviates atherosclerosis in ApoE(-/-) mice through up-regulation of SREBP2-mediated LDLR expression.
STING Suppresses Mitochondrial VDAC2 to Govern RCC Growth Independent of Innate Immunity.
Disrupted in renal carcinoma 2 (DIRC2/SLC49A4) is an H(+)-driven lysosomal pyridoxine exporter.
Negative regulation of TREM2-mediated C9orf72 poly-GA clearance by the NLRP3 inflammasome.
HERC2 promotes inflammation-driven cancer stemness and immune evasion in hepatocellular carcinoma by activating STAT3 pathway.
Dihydroartemisinin inhibits liver cancer cell migration and invasion by reducing ATP synthase production through CaMKK2/NCLX.
Scribble promotes fibrosis-dependent mechanisms of hepatocarcinogenesis by p53/PUMA-mediated glycolysis.
Biochemical Toxicological Study of Insulin Overdose in Rats: A Forensic Perspective.
Choroid plexus mast cells drive tumor-associated hydrocephalus.
Phosphorylation of the AMPARs regulated by protein kinase C (PKC) and protein interacting with C-kinase 1 (PICK1) contribute to orofacial neuropathic pain.
Prenylated PALM2 Promotes the Migration of Esophageal Squamous Cell Carcinoma Cells Through Activating Ezrin.
Environmentally relevant exposure to cypermethrin aggravates diet-induced diabetic symptoms in mice: The interaction between environmental chemicals and diet.
Unsaturated bond recognition leads to biased signal in a fatty acid receptor.
Golgi Phosphoprotein 3 Promotes Colon Cancer Cell Metastasis Through STAT3 and Integrin α3 Pathways.
Attenuation of ROS/Chloride Efflux-Mediated NLRP3 Inflammasome Activation Contributes to Alleviation of Diabetic Cardiomyopathy in Rats after Sleeve Gastrectomy.
A marine-derived small molecule induces immunogenic cell death against triple-negative breast cancer through ER stress-CHOP pathway.
Claudin-10 overexpression suppresses human clear cell renal cell carcinoma growth and metastasis by regulating ATP5O and causing mitochondrial dysfunction.
Hyperinsulinemia-induced microglial mitochondrial dynamic and metabolic alterations lead to neuroinflammation in vivo and in vitro.
Induction of A Disintegrin and Metalloproteinase with Thrombospondin motifs 1 by a rare variant or cognitive activities reduces hippocampal amyloid-β and consequent Alzheimer's disease risk.
Jiangtang Sanhao formula ameliorates skeletal muscle insulin resistance via regulating GLUT4 translocation in diabetic mice.
Stimulatory G-Protein α Subunit Modulates Endothelial Cell Permeability Through Regulation of Plasmalemma Vesicle-Associated Protein.
Hepatocyte-Conditional Knockout of Phosphatidylethanolamine Binding Protein 4 Aggravated LPS/D-GalN-Induced Acute Liver Injury via the TLR4/NF-κB Pathway.
Expression Regulation of Water Reabsorption Genes and Transcription Factors in the Kidneys of Lepus yarkandensis.
Estradiol Ameliorates Acute Kidney Ischemia-Reperfusion Injury by Inhibiting the TGF-βRI-SMAD Pathway.
Avasimibe Alleviates Disruption of the Airway Epithelial Barrier by Suppressing the Wnt/β-Catenin Signaling Pathway.
Extracellular HMGB1 Impairs Macrophage-Mediated Efferocytosis by Suppressing the Rab43-Controlled Cell Surface Transport of CD91.
Alpha-Asaronol Alleviates Dysmyelination by Enhancing Glutamate Transport Through the Activation of PPARγ-GLT-1 Signaling in Hypoxia-Ischemia Neonatal Rats.
Sinomenine Hydrochloride Promotes TSHR-Dependent Redifferentiation in Papillary Thyroid Cancer.
History of Previous Midlife Estradiol Treatment Permanently Alters Interactions of Brain Insulin-like Growth Factor-1 Signaling and Hippocampal Estrogen Synthesis to Enhance Cognitive Aging in a Rat Model of Menopause.
Geniposide inhibits SphK1 membrane targeting to restore macrophage polarization balance in collagen-induced arthritis mice.
Activation of the Chemokine Receptor CCR1 and Preferential Recruitment of Gαi Suppress RSV Replication: Implications for Developing Novel Respiratory Syncytial Virus Treatment Strategies.
Effects of apolipoprotein E on regulating insulin sensitivity via regulating insulin receptor signalosome in caveolae.
Identification of Marek's disease virus pUL56 homologue and analysis of critical amino acid stretches indispensable for its intracellular localization.
Comprehensive analysis identified a reduction in ATP1A2 mediated by ARID3A in abdominal aortic aneurysm.
Identification and functional analysis of two new de novo KCNMA1 variants associated with Liang-Wang syndrome.
Graphene oxide leads to mitochondrial-dependent apoptosis by activating ROS-p53-mPTP pathway in intestinal cells.
Homophilic ATP1A1 binding induces activin A secretion to promote EMT of tumor cells and myofibroblast activation.
Low-dose metformin targets the lysosomal AMPK pathway through PEN2.
Gamma frequency light flicker regulates amyloid precursor protein trafficking for reducing β-amyloid load in Alzheimer's disease model.
CX-5461 is a potent immunosuppressant which inhibits T cell-mediated alloimmunity via p53-DUSP5.
lncRNA HITT inhibits metastasis by attenuating Rab5-mediated endocytosis in lung adenocarcinoma.
A novel and efficient murine model of Bietti crystalline dystrophy.
Alteration in Rab11-mediated endocytic trafficking of LDL receptor contributes to angiotensin II-induced cholesterol accumulation and injury in podocytes.
Identification of different proteins binding to Na, K-ATPase α1 in LPS-induced ARDS cell model by proteomic analysis.
Insulin alleviates LPS-induced ARDS via inhibiting CUL4B-mediated proteasomal degradation and restoring expression level of Na,K-ATPase α1 subunit through elevating HCF-1.
Changes in the expression of drug-metabolising enzymes and drug transporters in mice with collagen antibody-induced arthritis.
Multiple Mild Stimulations Reduce Membrane Distribution of CX3CR1 Promoted by Annexin a1 in Microglia to Attenuate Excessive Dendritic Spine Pruning and Cognitive Deficits Caused by a Transient Ischemic Attack in Mice.
EXOC4 Promotes Diffuse-Type Gastric Cancer Metastasis via Activating FAK Signal.
CDER167, a dual inhibitor of URAT1 and GLUT9, is a novel and potent uricosuric candidate for the treatment of hyperuricemia.
CRISPR/Cas9 delivery by NIR-responsive biomimetic nanoparticles for targeted HBV therapy.
Cancer cell-expressed BTNL2 facilitates tumour immune escape via engagement with IL-17A-producing γδ T cells.
Hyperglycemia induces corneal endothelial dysfunction through attenuating mitophagy.
Amino acid starvation-induced LDLR trafficking accelerates lipoprotein endocytosis and LDL clearance.
Avian Hepatitis E Virus ORF2 Protein Interacts with Rap1b to Induce Cytoskeleton Rearrangement That Facilitates Virus Internalization.
Heat Shock Protein Member 8 (HSPA8) Is Involved in Porcine Reproductive and Respiratory Syndrome Virus Attachment and Internalization.
Blockade of CBX4-mediated β-catenin SUMOylation attenuates airway epithelial barrier dysfunction in asthma.
CYLD deubiquitinates plakoglobin to promote Cx43 membrane targeting and gap junction assembly in the heart.
Extracellular matrix modulating enzyme functionalized biomimetic Au nanoplatform-mediated enhanced tumor penetration and synergistic antitumor therapy for pancreatic cancer.
KIF17 Modulates Epileptic Seizures and Membrane Expression of the NMDA Receptor Subunit NR2B.
Paeoniflorin-6'O-benzene sulfonate suppresses fibroblast-like synoviocytes proliferation and migration in rheumatoid arthritis through regulating GRK2-Gβγ interaction.
C1q/tumour necrosis factor-related protein-3 alleviates high-glucose-induced lipid accumulation and necroinflammation in renal tubular cells by activating the adenosine monophosphate-activated protein kinase pathway.
Functional characterization of human organic anion transporter 10 (OAT10/SLC22A13) as an orotate transporter.
Small-Molecule Induction Promotes Corneal Endothelial Cell Differentiation From Human iPS Cells.
Pentadecanoic acid promotes basal and insulin-stimulated glucose uptake in C2C12 myotubes.
FXYD6 Regulates Chemosensitivity by Mediating the Expression of Na+/K+-ATPase α1 and Affecting Cell Autophagy and Apoptosis in Colorectal Cancer.
The cellular prion protein interacts with and promotes the activity of Na,K-ATPases.
GRIN2A Variants Associated With Idiopathic Generalized Epilepsies.
The Extracellular Matrix Enriched With Exosomes for the Treatment on Pulmonary Fibrosis in Mice.
High-Salt Attenuates the Efficacy of Dapagliflozin in Tubular Protection by Impairing Fatty Acid Metabolism in Diabetic Kidney Disease.
Claudin-5 Affects Endothelial Autophagy in Response to Early Hypoxia.
DEPTOR stabilizes ErbB2 to promote the proliferation and survival of ErbB2-positive breast cancer cells.
Previous estradiol treatment during midlife maintains transcriptional regulation of memory-related proteins by ERα in the hippocampus in a rat model of menopause.
Metformin alleviates inflammation through suppressing FASN-dependent palmitoylation of Akt.
Nicotinamide ameliorates energy deficiency and improves retinal function in Cav-1(-/-) mice.
IL-37b alleviates endothelial cell apoptosis and inflammation in Kawasaki disease through IL-1R8 pathway.
MicroRNA-191 blocking the translocation of GLUT4 is involved in arsenite-induced hepatic insulin resistance through inhibiting the IRS1/AKT pathway.
Down-regulation of A(3)AR signaling by IL-6-induced GRK2 activation contributes to Th17 cell differentiation.
Specific protein kinase C isoform exerts chronic inhibition on the slowly activating delayed-rectifier potassium current by affecting channel trafficking.
A broadly neutralizing humanized ACE2-targeting antibody against SARS-CoV-2 variants.
Humanin Alleviates Insulin Resistance in Polycystic Ovary Syndrome: A Human and Rat Model-Based Study.
Ultraviolet B irradiation decreases CXCL10 expression in keratinocytes through endoplasmic reticulum stress.
Olfactomedin-3 Enhances Seizure Activity by Interacting With AMPA Receptors in Epilepsy Models.
Transient Receptor Potential Channel 6 Knockout Ameliorates Kidney Fibrosis by Inhibition of Epithelial-Mesenchymal Transition.
S-Adenosylmethionine Alleviates Amyloid-β-Induced Neural Injury by Enhancing Trans-Sulfuration Pathway Activity in Astrocytes.
Aplysin Retards Pancreatic Necrosis and Inflammatory Responses in NOD Mice by Stabilizing Intestinal Barriers and Regulating Gut Microbial Composition.
Comprehensive analysis of the expression of sodium/potassium-ATPase α subunits and prognosis of ovarian serous cystadenocarcinoma.
A novel mutation of LIM2 causes autosomal dominant membranous cataract in a Chinese family.
PD-1-Mediated PI3K/Akt/mTOR, Caspase 9/Caspase 3 and ERK Pathways Are Involved in Regulating the Apoptosis and Proliferation of CD4(+) and CD8(+) T Cells During BVDV Infection in vitro.
Exogenous spermine attenuates rat diabetic cardiomyopathy via suppressing ROS-p53 mediated downregulation of calcium-sensitive receptor.
Anti-human serum albumin autoantibody may be involved in the pathogenesis of autoimmune bullous skin diseases.
FLIM-FRET-Based Structural Characterization of a Class-A GPCR Dimer in the Cell Membrane.
Loss of mitochondrial protein CHCHD10 in skeletal muscle causes neuromuscular junction impairment.
NR2B receptor- and calpain-mediated KCC2 cleavage resulted in cognitive deficiency exposure to isoflurane.
Gamabufotalin induces a negative feedback loop connecting ATP1A3 expression and the AQP4 pathway to promote temozolomide sensitivity in glioblastoma cells by targeting the amino acid Thr794.
Subcellular trafficking of tubular MDM2 implicates in acute kidney injury to chronic kidney disease transition during multiple low-dose cisplatin exposure.
Alisol A-24-acetate promotes glucose uptake via activation of AMPK in C2C12 myotubes.
Oncogenic role of TYRO3 receptor tyrosine kinase in the progression of pancreatic cancer.
PLRP2 selectively localizes synaptic membrane proteins via acyl-chain remodeling of phospholipids.
Palmitoylation of the Bovine Foamy Virus Envelope Glycoprotein Is Required for Viral Replication.
High salt diet elevates the mean arterial pressure of SLC14α1 gene depletion mice.
AMPK facilitates intestinal long-chain fatty acid uptake by manipulating CD36 expression and translocation.
Knockdown of long noncoding RNA dreh facilitates cell surface GLUT4 expression and glucose uptake through the involvement of vimentin in 3T3-L1 adipocytes.
The Binding of PD-L1 and Akt Facilitates Glioma Cell Invasion Upon Starvation via Akt/Autophagy/F-Actin Signaling.
Fucoidan prevent murine autoimmune diabetes via suppression TLR4-signaling pathways, regulation DC/Treg induced immune tolerance and improving gut microecology.
TMEM25 modulates neuronal excitability and NMDA receptor subunit NR2B degradation.
CXCR7 regulates epileptic seizures by controlling the synaptic activity of hippocampal granule cells.
Distribution of aquaporins and sodium transporters in the gastrointestinal tract of a desert hare, Lepus yarkandensis.
Laminin α4 overexpression in the anterior lens capsule may contribute to the senescence of human lens epithelial cells in age-related cataract.
CP-25 combined with MTX/ LEF ameliorates the progression of adjuvant-induced arthritis by the inhibition on GRK2 translocation.
Pantoprazole pretreatment elevates sensitivity to vincristine in drug-resistant oral epidermoid carcinoma in vitro and in vivo.
GRK2 Mediated Abnormal Transduction of PGE2-EP4-cAMP-CREB Signaling Induces the Imbalance of Macrophages Polarization in Collagen-Induced Arthritis Mice.
Rapid affinity purification of intracellular organelles using a twin strep tag.
The exocyst complex regulates insulin-stimulated glucose uptake of skeletal muscle cells.
Identification of Protein Kinase C Isoforms Involved in Type 1 Diabetic Encephalopathy in Mice.
Proscillaridin A exerts anti-tumor effects through GSK3β activation and alteration of microtubule dynamics in glioblastoma.
Neuritin promotes neurite and spine growth in rat cerebellar granule cells via L-type calcium channel-mediated calcium influx.
Autophagy suppresses self-renewal ability and tumorigenicity of glioma-initiating cells and promotes Notch1 degradation.
Downregulation of Aquaporins (AQP1 and AQP5) and Na,K-ATPase in Porcine Reproductive and Respiratory Syndrome Virus-Infected Pig Lungs.
Succinate induces aberrant mitochondrial fission in cardiomyocytes through GPR91 signaling.
DRm217 attenuates myocardial ischemia-reperfusion injury via stabilizing plasma membrane Na(+)-K(+)-ATPase, inhibiting Na(+)-K(+)-ATPase/ROS pathway and activating PI3K/Akt and ERK1/2.
Robust diagnosis of Ewing sarcoma by immunohistochemical detection of super-enhancer-driven EWSR1-ETS targets.
Prostaglandin E2 increases migration and proliferation of human glioblastoma cells by activating transient receptor potential melastatin 7 channels.
EMC10 governs male fertility via maintaining sperm ion balance.
Dexmedetomidine impairs P‑glycoprotein‑mediated efflux function in L02 cells via the adenosine 5'‑monophosphate‑activated protein kinase/nuclear factor‑κB pathway.
FBW7 increases the chemosensitivity of pancreatic cancer cells to gemcitabine through upregulation of ENT1.
Succinate accumulation impairs cardiac pyruvate dehydrogenase activity through GRP91-dependent and independent signaling pathways: Therapeutic effects of ginsenoside Rb1.
Core 3 mucin-type O-glycan restoration in colorectal cancer cells promotes MUC1/p53/miR-200c-dependent epithelial identity.
PKCζ phosphorylates TRAF2 to protect against intestinal ischemia-reperfusion-induced injury.
Vitamin D supplementation inhibits oxidative stress and upregulate SIRT1/AMPK/GLUT4 cascade in high glucose-treated 3T3L1 adipocytes and in adipose tissue of high fat diet-fed diabetic mice.
Inhibition of Calcineurin A by FK506 Suppresses Seizures and Reduces the Expression of GluN2B in Membrane Fraction.
Regulation of Na(+)-K(+)-ATPase effected high glucose-induced myocardial cell injury through c-Src dependent NADPH oxidase/ROS pathway.
Activation of Na(+)-K(+)-ATPase with DRm217 attenuates oxidative stress-induced myocardial cell injury via closing Na(+)-K(+)-ATPase/Src/Ros amplifier.
CLIC1 Inhibition Attenuates Vascular Inflammation, Oxidative Stress, and Endothelial Injury.
Activation of Na+/K+-ATPase attenuates high glucose-induced H9c2 cell apoptosis via suppressing ROS accumulation and MAPKs activities by DRm217.
Arrhythmogenic cardiomyopathy in a patient with a rare loss-of-function KCNQ1 mutation.
20-HETE induces hyperglycemia through the cAMP/PKA-PhK-GP pathway.
Wan Q, Ye T, Gu J, Ma Y, Qin W, Yan J, Rao J, Chen L, Hao D, Tay FR, Jiao K, Niu L
Science bulletin 2026 May 15;71(9):2300-2315
Science bulletin 2026 May 15;71(9):2300-2315
Esflurbiprofen exerts a fast-onset antidepressant effect by blocking SERT-nNOS interaction.
Chen YQ, Ye JR, Wang SS, Peng Y, Zhou R, Yuan RL, Wang WF, Chu SF, Zhang Z, Chen NH
Acta pharmacologica Sinica 2026 Mar;47(3):593-607
Acta pharmacologica Sinica 2026 Mar;47(3):593-607
Alpha-Fetoprotein Stimulates Cleavage of Membranal MICA/B on Liver Cancer Cell Lead to Escape Immune Surveillance of Natural Killer Cells.
Li X, Feng S, Wu X, Pan Y, Zhou Y, Liu K, Lin B, Li W, Li M, Zhu M
Journal of cellular and molecular medicine 2026 Mar;30(5):e71076
Journal of cellular and molecular medicine 2026 Mar;30(5):e71076
In Vitro Evaluation of Cadmium-Induced Phosphate Reabsorption Impairment.
Fujishiro H, Nakayama R, Takahashi M, Tamoto A, Taguchi H, Takeuchi K, Himeno S, Sumi D
Journal of applied toxicology : JAT 2026 Mar 5;
Journal of applied toxicology : JAT 2026 Mar 5;
FAK/SRC-JNK axis promotes ferroptosis via upregulating ACSL4 expression.
Qin J, Ma S, Wang J, Huang S, Luan J, He J, Hou G, Sun N, Zhang W, Gao M
Cell death & disease 2026 Mar 20;17(1)
Cell death & disease 2026 Mar 20;17(1)
Membrane-camouflaged nanoparticle alleviates intervertebral disc degeneration via oxidative stress suppression and autophagy activation.
Niu Z, Fan Y, Chen J, Ji L, Tong Y, Yao L, Ding S, Xu H, Chen J, Zhang Q, Zhao C, Chen J, Bi Q, Xia C
Materials today. Bio 2026 Jun;38:103038
Materials today. Bio 2026 Jun;38:103038
Teleost GSDMEc regulates GSDMEa-mediated pyroptosis.
Xu H, Wu M, Wang Y, Jiao Y, Chen Y, Yuan Z, Sun L
Journal of advanced research 2026 Jan;79:105-119
Journal of advanced research 2026 Jan;79:105-119
LRRC8A Mediates Ischemic Neuronal Injury by Potentiating NMDA Receptor Activity and Activating Mitochondrial Apoptotic Pathway.
Qian C, Huang L, Chen Y, Lv J, Wang Z, Dai J, Luo Y
Cell biology international 2026 Jan;50(1):e70118
Cell biology international 2026 Jan;50(1):e70118
The USP1-WDR48 deubiquitinase complex functions as a molecular switch regulating tumor-associated macrophage activation and anti-tumor response.
Han D, Wang L, Jiang S, Su P, Chen B, Zhao W, Chen T, Zhang N, Wang X, Liang Y, Li Y, Li C, Chen X, Luo D, Yang Q
Cell death and differentiation 2026 Jan;33(1):92-110
Cell death and differentiation 2026 Jan;33(1):92-110
Tuina Inhibits Synaptic Plasticity Through the Astrocytic NDRG2/GLT-1 Pathway to Alleviate Neuropathic Pain.
Zhang H, Chen L, Jiang J, Huang L, Huang H, Huang L, Chen S, Lin Z
Journal of cellular and molecular medicine 2026 Jan;30(1):e71013
Journal of cellular and molecular medicine 2026 Jan;30(1):e71013
Downregulation of BST2 Rescues Cochlear Nerve Demyelination in Age-Related Hearing Loss via Enhancing Schwann Cell Migration.
Liu M, Li Q, Cao H, Yin H, Yang J, Liu T, Wang J, Zhao L, Wang B
Aging cell 2026 Jan;25(1):e70325
Aging cell 2026 Jan;25(1):e70325
The allyl isothiocyanate (AITC) isolated from mustard (Sinapis alba L.) oil exerts antidepressant effects by blocking the interaction between SERT and nNOS.
Wang WF, Geng ZY, Zhang PX, Ye JR, Yuan RL, Wu RJ, Chen YQ, Wang ZZ, Chu SF, Zhang Z, Chen NH
Journal of ethnopharmacology 2026 Feb 28;357:120876
Journal of ethnopharmacology 2026 Feb 28;357:120876
Hybrid macrophage-mitochondria extracellular vesicles for mitochondrial ROS regulation in diabetic wounds.
Fan L, Zhang C, Xu Z, Li Z, Zhang B, Li H, Wang J, Wei Z, Han J, Guan H, Peng B, Voelcker NH, Yang X
Nature communications 2026 Feb 28;17(1)
Nature communications 2026 Feb 28;17(1)
Psoralen Promotes Direct Chemical Reprogramming of Mouse Embryonic Fibroblasts into Osteoblast-like Cells.
Li W, Liu H, Wan X, Cheng D, Zhu R, Zhang Z
Pharmaceutics 2026 Feb 23;18(2)
Pharmaceutics 2026 Feb 23;18(2)
Claudin18.2 promote gastric cancer proliferation by activating MCM2/5.
Zheng B, Fu M, Lou F, He Y, Zhao L, Huang X, Xie X, Tan W, Chen Q, Zhang W, Hong Y, Rong K, Lu Y, Zhan P, Tu J, Shi H, Hu T, Xiao L
Scientific reports 2026 Feb 23;16(1)
Scientific reports 2026 Feb 23;16(1)
Synergistic mechanical and therapeutic modulation of engineered tumor cell-derived microparticles for enhanced cancer treatment.
Zhang X, Zhang K, Zhu Y, Xu S, Li S, Liu H, Lv W, Xie Z, Huang Y, Li X, Bie N, Wang S, Huang Z, Zheng H, Qin C, Yang X, Gan L, Yong T
Cell reports. Medicine 2026 Feb 17;7(2):102591
Cell reports. Medicine 2026 Feb 17;7(2):102591
Targeting SLC5A2 suppresses colorectal tumour development by enhancing NK cell activity through extracellular vesicle-dependent MICA/B signalling.
Xiao J, Wu J, Deng F, Liu C, Chen Y, Shen K, Wang C, Lin W, Liu W, Ning Z, Zhou R, Zhao L
Clinical and translational medicine 2026 Apr;16(4):e70657
Clinical and translational medicine 2026 Apr;16(4):e70657
Extracellular Vesicle-Mediated Nucleolin Transfer in Glioblastoma: A Targetable Axis Driving Blood-Tumour Barrier Formation.
Chen H, Zhao J, Qiu F, Wang Z, Li J, Zhang L, Lu A, Liang C
Journal of extracellular vesicles 2026 Apr;15(4):e70268
Journal of extracellular vesicles 2026 Apr;15(4):e70268
ATP1A1 enhances porcine reproductive and respiratory syndrome virus type 2 attachment and internalization.
Yang H, Li B, Yin X, Cristianto Pratama A, He F
mBio 2026 Apr 8;17(4):e0389625
mBio 2026 Apr 8;17(4):e0389625
Macrophage-Targeted Nanocarriers Based on Tetrahedral DNA Nanostructure Alleviate Sepsis-Induced Acute Lung Injury by Triple-Pathway Suppression of Pyroptosis.
Zhang Y, Pan M, Ma F, He C, Gu Q, Wang Y, Pan Z, Wang H, Yan Y, Fu X, Jia Y, Duan H, Wu Y, Wei Z, Wang J, Li B, Liao Y, Zhan L
ACS applied materials & interfaces 2026 Apr 15;18(14):20128-20145
ACS applied materials & interfaces 2026 Apr 15;18(14):20128-20145
EVA1A Regulates Hepatic Lipid Homeostasis by Modulating CD36 Expression and Its Palmitoylation.
Yang D, Li L, Zang K, Ma W, Yang Y, Sun Y, Zhang B, Gong Z, Yu M, Du Q, Liu X, Wang Z, Xu Q, Li N
Research (Washington, D.C.) 2025;8:1001
Research (Washington, D.C.) 2025;8:1001
Na(+)/K(+)-ATPase Modulates Purinergic P2X3 Receptor Function to Drive Bone Cancer Pain.
Huang S, Peng B, Dong W, He J, Chen H, Bian JS
Research (Washington, D.C.) 2025;8:0932
Research (Washington, D.C.) 2025;8:0932
Role of VDAC1 in hepatocyte apoptosis during acute liver injury in rats induced by obstructive jaundice.
Liu J, Hu J, Xu H, Yan L, Yao J, Cao B
Iranian journal of basic medical sciences 2025;28(1):87-97
Iranian journal of basic medical sciences 2025;28(1):87-97
G Protein-Coupled Receptor 30 Attenuates Neuronal Pyroptosis Induced by Subarachnoid Hemorrhage.
Peng J, Hu X, He J, Xia Y
Mediators of inflammation 2025;2025:3585885
Mediators of inflammation 2025;2025:3585885
NCAPG promotes the malignant progression of endometrioid cancer through LEF1/SEMA7A/PI3K-AKT.
Ren Z, Li X, Fu C
Journal of Cancer 2025;16(2):445-459
Journal of Cancer 2025;16(2):445-459
Unveiling ammonia-induced cell death: a new frontier in clear cell renal cell carcinoma prognosis.
Yu P, Zhong Q, Wang X, Liu Y, Liu Q, Zhang Y, Lu J, Dong Y, Han CH
Frontiers in immunology 2025;16:1636977
Frontiers in immunology 2025;16:1636977
Impact of the ENPP1 mutation on bone mineralization and ectopic calcification: evidence from in vitro and in vivo models.
Wu W, Liu L, Shi Y, Zhang Y, Qiu R, Yan F
Frontiers in endocrinology 2025;16:1566392
Frontiers in endocrinology 2025;16:1566392
ZDHHC14 and APT2 regulate the palmitoylation of HSV-2 gB.
Chen Y, Yu G, Gao S, Zhang L
Virology 2025 Sep;610:110614
Virology 2025 Sep;610:110614
LncDARS-AS1 Regulates ATP1A1 Stability and Enhances Na(+)/K(+) ATPase Activity to Promote Osteosarcoma Metastasis.
Xu M, Wei J, Feng X, Zhang Q, Chen J, Wang X, Zhan X, Lu B, Guo W, Cheng M, Huang R, Xu S, Zou C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(34):e03486
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(34):e03486
Adiponectin pathway regulates cerebral metabolic dysfunction and neuroinflammation via the AdipoR1/PI3K/Akt axis in Perioperative Neurocognitive Disorder.
Zhang Z, Hu C, Li B, Zhong C, Guo L, Su B, Chen H, Xie H
BMC geriatrics 2025 Sep 26;25(1):721
BMC geriatrics 2025 Sep 26;25(1):721
Metformin alleviates hyperkalemia-induced arrhythmia and cardiac injury in mice through decreasing SK2 and intracellular Ca(2).
Cui J, Adu-Amankwaah J, Song H, Wang R, Song N, Liu K, Yang D, Du M, Kong D, Wang S, Mi S, Tan R
Life sciences 2025 Sep 1;376:123740
Life sciences 2025 Sep 1;376:123740
Na+,K+-ATPase α isoforms in sperm show a highly structured and distinct pattern of distribution.
Oishee MJ, McDermott JP, Sánchez G, Blanco G
Reproduction (Cambridge, England) 2025 Sep 1;170(3)
Reproduction (Cambridge, England) 2025 Sep 1;170(3)
Role of Extracellular Histidine Residues for the Function and pH Sensitivity of Human Organic Anion Transporting Polypeptide 1B3.
Han W, Liu H, Liang T, Li L, Huan R, Gui C
Proteins 2025 Oct;93(10):1876-1885
Proteins 2025 Oct;93(10):1876-1885
GRK2-mediated phosphorylation and de-succinylation of PKM2 reduce macrophage glycolysis in rheumatoid arthritis.
Yang XZ, Zhang WK, Zhu ZQ, Zhao W, Luo LL, Wang LP, Zhao YJ, Chang Y, Wei W
Acta pharmacologica Sinica 2025 Oct;46(10):2693-2706
Acta pharmacologica Sinica 2025 Oct;46(10):2693-2706
USP47 Regulates Excitatory Synaptic Plasticity and Modulates Seizures in Murine Models by Blocking Ubiquitinated AMPAR Degradation.
Yang J, Zhang H, Wang Y, Luo Y, Zheng W, Liu Y, Jiang Q, Deng J, Liu Q, Zhang P, Huang H, Yu C, Xu Z, Chen Y
Neuroscience bulletin 2025 Oct;41(10):1805-1823
Neuroscience bulletin 2025 Oct;41(10):1805-1823
Astragaloside IV-PESV facilitates pyroptosis by enhancing palmitoylation of GSDMD protein mediated by ZDHHC1.
You X, Li H, Li Q, Zhang Q, Cao Y, Fu W, Wang B
Naunyn-Schmiedeberg's archives of pharmacology 2025 Oct;398(10):13925-13939
Naunyn-Schmiedeberg's archives of pharmacology 2025 Oct;398(10):13925-13939
DEPTOR suppresses lymphomagenesis by promoting EGFR degradation via HUWE1 E3 ligase.
Xiong X, Chen X, Shao S, Cui D, Qu R, Wang B, Ma Y, Pan H, Sun Y, Zhao Y
Cell death and differentiation 2025 Oct;32(10):1820-1832
Cell death and differentiation 2025 Oct;32(10):1820-1832
Elevated Release of Presynaptic Glutamate: The Potential Pathogenesis of Anti-NMDAR Encephalitis-Associated Seizures.
Huang H, Huang Y, Li S, Wu Y, Yang S, Wu Y
CNS neuroscience & therapeutics 2025 Oct;31(10):e70585
CNS neuroscience & therapeutics 2025 Oct;31(10):e70585
Nebulized Inhalation of Engineered Extracellular Vesicles to Destruct Pre-metastatic Niche and Inhibit Postoperative Lung Metastasis in a Mouse Model.
Wang X, Han X, Yuan H, Zhang X, Kang Y, Wang Y, Song P, Su X, Chen Z, Liang H, Zheng X, Yan J, Zhang H
ACS nano 2025 Oct 14;19(40):35752-35769
ACS nano 2025 Oct 14;19(40):35752-35769
Microtubule-dependent regulation of TMEM16A-mediated Ca(2+)-activated Cl(-) currents in vascular smooth muscle cells.
Hemmi R, Suzukawa A, Fujiwara M, Kondo R, Suzuki Y, Yamamura A, Yamamura H
Journal of pharmacological sciences 2025 Nov;159(3):202-207
Journal of pharmacological sciences 2025 Nov;159(3):202-207
ApoE is Secreted as a Lipid Nanoparticle by Mammalian Cells: Implications for Alzheimer's Disease Pathogenesis.
Hernandez Arriaza R, Reil D, Fatuzzo N, Fu M, Dai Y, Fernandez Martinez D, Jiang H, Holtzman DM, Greicius MD, Khosla C
Biochemistry 2025 Nov 4;64(21):4387-4399
Biochemistry 2025 Nov 4;64(21):4387-4399
Rab26 promotes hypoxia-induced hyperproliferation of PASMCs by modulating the AT1R-STAT3-YAP axis.
You Z, Huang Q, Zeng L, Tian X, Zhang W, Wei D, Fu J, Xu L, Ren L, Zhao Y, Qian H, Wang G, Zhou X, He B
Cellular and molecular life sciences : CMLS 2025 Nov 13;82(1):396
Cellular and molecular life sciences : CMLS 2025 Nov 13;82(1):396
NLRP3 Inflammasome Activation Contributes to Seizure Susceptibility in Anti-NMDAR Encephalitis: Evidence from Patients and a Mouse Model.
Luo H, Yang J, Li Y, Song H, Yang X, Han Z, Huang D, Cheng L, Ma J, Jiang L
Molecular neurobiology 2025 Nov 11;63(1):25
Molecular neurobiology 2025 Nov 11;63(1):25
Levofloxacin-induced seizure susceptibility involves both enhanced glutamatergic and impaired GABAergic synaptic function.
He K, He L, Wei X, Wang X, Zhou M, Cao Y, Luo X, He J
Brain research 2025 Nov 1;1866:149929
Brain research 2025 Nov 1;1866:149929
PCSK9 promotes progression of anaplastic thyroid cancer through E-cadherin endocytosis.
Zhang Y, Su W, Ji X, Yang Z, Guan Q, Pang Y, Zhong L, Wang Y, Xiang J
Cell death & disease 2025 May 6;16(1):362
Cell death & disease 2025 May 6;16(1):362
Rab11a-dependent recycling of Glut3 inhibits seizure-induced neuronal disulfidptosis by alleviating glucose deficiency.
Li S, He J, Kuang H, Wang X, Zhou M, Li D, Kang B, He H, He L, Lin W, Lv Y
Cell & bioscience 2025 May 28;15(1):69
Cell & bioscience 2025 May 28;15(1):69
Restoring Autophagy by Exercise Ameliorates Insulin Resistance Partly via Calcineurin-Driven TFEB Nuclear Translocation.
Wang P, Li J, Li CG, Zhou X, Chen X, Zhu M, Wang H
Clinical and experimental pharmacology & physiology 2025 Mar;52(3):e70010
Clinical and experimental pharmacology & physiology 2025 Mar;52(3):e70010
Micropeptide hSPAR regulates glutamine levels and suppresses mammary tumor growth via a TRIM21-P27KIP1-mTOR axis.
Huang Y, Lu H, Liu Y, Wang J, Xia Q, Shi X, Jin Y, Liang X, Wang W, Ma X, Wang Y, Gong M, Li C, Cang C, Cui Q, Chen C, Shen T, Liu L, Wang X
The EMBO journal 2025 Mar;44(5):1414-1441
The EMBO journal 2025 Mar;44(5):1414-1441
The essential role of sphingolipids in TRPC5 ion channel localization and functionality within lipid rafts.
Wan J, Hu Z, Zhu H, Li J, Zheng Z, Deng Z, Lu J, Chen Y, Chen GL, Zeng B, Zhang J, Duan J
Pharmacological research 2025 Mar;213:107648
Pharmacological research 2025 Mar;213:107648
A subcellular map of translational machinery composition and regulation at the single-molecule level.
Zhang Z, Xu A, Bai Y, Chen Y, Cates K, Kerr C, Bermudez A, Susanto TT, Wysong K, García Marqués FJ, Nolan GP, Pitteri S, Barna M
Science (New York, N.Y.) 2025 Mar 7;387(6738):eadn2623
Science (New York, N.Y.) 2025 Mar 7;387(6738):eadn2623
Pathogenic germline variants in Chinese pancreatic adenocarcinoma patients.
Yin X, Shen H, Wang H, Wang Q, Zhang S, Zhang C, Jia Q, Guo S, Xu X, Zhang W, Li B, Shi X, Gao S, Shi M, Zhao X, Wang S, Han J, Zhang G, Li Y, Li P, Jing W, Song B, Zheng K, Li G, Zhang Y, Jiang H, Wu C, Song Z, Niu G, Zhang Q, Guo J, Sun Z, Han F, Li Y, Gao D, Jin H, Yang H, Li J, Jin G
Nature communications 2025 Mar 5;16(1):2214
Nature communications 2025 Mar 5;16(1):2214
PTPN23-dependent activation of PI3KC2α is a therapeutic vulnerability of BRAF-mutant cancers.
He Y, Li W, Zhang M, Wang H, Lin P, Yu Y, Huang B, Hao M, He J, Kong W, Luo D, Xu T, Wang J, Huang Y, Zhao Q, Liu Y, Zhang J, Nian Y, Zhang L, Zhu B, Yin C
The Journal of experimental medicine 2025 Mar 3;222(3)
The Journal of experimental medicine 2025 Mar 3;222(3)
The Frmpd3 Protein Regulates Susceptibility to Epilepsy by Combining with GRIP and GluA2.
Jia Y, Zhan J, Huang P, Li X, Hong D, Lu X
Current issues in molecular biology 2025 Mar 26;47(4)
Current issues in molecular biology 2025 Mar 26;47(4)
Target Identification of Marine Natural Product Odoamide:Odoamide Induces Apoptotic Cell Death by Targeting ATPase Na(+)/K(+) Transporting Subunit Alpha 1 (ATP1A1).
Katsumata R, Kamiyama H, Sagane K, Yamamoto Y, Azuma H, Nishibata K, Kotake Y, Nakano S, Okubo S, Teruya T, Okuda A, Takase Y
Chembiochem : a European journal of chemical biology 2025 Mar 15;26(6):e202400762
Chembiochem : a European journal of chemical biology 2025 Mar 15;26(6):e202400762
The wheat stripe rust effector PstEXLX1 inhibits formate dehydrogenase activity to suppress immunity in wheat.
Lu J, Sun K, Yang W, Mou Y, Zhang R, Voegele RT, Kang Z, Guo J, Guo J
Plant physiology 2025 Mar 1;197(3)
Plant physiology 2025 Mar 1;197(3)
Functional characteristics of equilibrative nucleoside transporter 2 (ENT2/SLC29A2) for the transport of urate as a newly identified substrate.
Matake I, Yasujima T, Matsuo H, Toyoda Y, Kawamura Y, Takada T, Inoue K, Yamashiro T, Yuasa H
Drug metabolism and pharmacokinetics 2025 Jun;62:101048
Drug metabolism and pharmacokinetics 2025 Jun;62:101048
Alpha-synuclein Fibrils Inhibit Activation of the BDNF/ERK Signaling Loop in the mPFC to Induce Parkinson's Disease-like Alterations with Depression.
Ma Z, Xu Y, Lian P, Wu Y, Liu K, Zhang Z, Tang Z, Yang X, Cao X
Neuroscience bulletin 2025 Jun;41(6):951-969
Neuroscience bulletin 2025 Jun;41(6):951-969
Leucyl-tRNA synthetase regulates casein synthesis in dairy cows via the mTORC1-LAT1 pathway.
Ke Y, Du X, Chen B, Chen X, Song C, Fang X, Wang Y, Zhang C
Animal bioscience 2025 Jun;38(6):1259-1271
Animal bioscience 2025 Jun;38(6):1259-1271
Membrane biomimetic nanoenzyme-incorporated hybrid glycyrrhizic acid hydrogel for precise mitochondrial ROS scavenging for osteoarthritis treatment.
Fan Y, Niu Z, Yin L, Yao L, Ding S, Tong Y, Wang J, Hong Z, Chen J, Zhang Q, Ji L, Chen J, Xia C, Bi Q
Materials today. Bio 2025 Jun;32:101778
Materials today. Bio 2025 Jun;32:101778
K(+)-H(+) coupling strategy for immune regulation and bone defect repair.
Hu L, Yang K, Chen Y, Wang H, Fu Z, Jiang L, Xu J, Tian H, Zhu Y, Dai Z, Li Y, Chen X, Lin X, Chen P, Gu C, Fan S
Materials today. Bio 2025 Jun;32:101744
Materials today. Bio 2025 Jun;32:101744
AMPK phosphorylation of K(Ca)2.3 alleviates angiotensin II-induced endothelial dysfunction.
Pang ZD, Wang Y, Han MZ, She G, Sun X, Bai RY, Lai BC, Zhang Y, Du XJ, Shyy JY, Deng XL
Biochemical pharmacology 2025 Jun;236:116880
Biochemical pharmacology 2025 Jun;236:116880
Extracellular HSP90-Facilitated Degradation of Extracellular and Membrane Proteins by Bifunctional Small Molecules.
Zhang D, Li J, Liang Y, Li T, Ji M, Liu X, Li W, Chen P, Zhang J, Yang Z, Wang L, Chen H
Journal of medicinal chemistry 2025 Jun 26;68(12):12641-12657
Journal of medicinal chemistry 2025 Jun 26;68(12):12641-12657
PARP inhibition elicits NK cell-associated immune evasion via potentiating HLA-G expression in tumor.
Wang S, Xia Y, Qian Y, Pan W, Huang P, Jin N, Li X, Xu C, Liu D, Zhao G, Fang Y, Nicot C, Gao Q
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2025 Jul;81:101247
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2025 Jul;81:101247
Macrophage-mimetic liposomes co-delivering ceria and Ac2-26 peptide for penumbra protection in ischemic stroke.
Bai L, Li N, Li H, Dai Y, Bai Y, Ma F, Sha D, Xia S, Xu Y, Cao X
Journal of nanobiotechnology 2025 Jul 5;23(1):488
Journal of nanobiotechnology 2025 Jul 5;23(1):488
Genetically engineered chondrocyte-mimetic nanoplatform attenuates osteoarthritis by blocking IL-1β and restoring sirtuin-3.
Deng C, Yu L, Zhao X, Chen Y, Mei J, Wei J, Chen X, Lei G, Zeng C
Science advances 2025 Jul 25;11(30):eadv4238
Science advances 2025 Jul 25;11(30):eadv4238
Preparation, Characterization, and Functional Evaluation of a Novel Recombinant Hypoglycemic Protein with Multifunctional Effects.
Liu T, Ma X, Duan Z
Journal of agricultural and food chemistry 2025 Jul 23;73(29):18366-18379
Journal of agricultural and food chemistry 2025 Jul 23;73(29):18366-18379
Electrically Driven Chimeric Extracellular Vesicles Crossing the Fundus Barrier for Retinoblastoma Treatment.
Shi H, Qin X, Jiang X, Jin X, Zhang J, Li H, Fan D, Song B, Chu B, Wang H, He Y
ACS nano 2025 Jul 22;19(28):26200-26216
ACS nano 2025 Jul 22;19(28):26200-26216
AF6 regulates intestinal IgA via crosstalk between intestinal epithelial cells and immune cells in inflammatory bowel disease.
Lu L, Xu K, Qu H, Song L, Song Y, Wu Y, Sun X, Kong J, Wen Q, Jiao J, Liu Z, Xia J, Zhan L
iScience 2025 Jul 18;28(7):112658
iScience 2025 Jul 18;28(7):112658
CLDN4 palmitoylation promotes hepatic-to-biliary lineage transition and lenvatinib resistance in hepatocellular carcinoma.
Xu M, Zheng Y, Chen J, Gao C, Zhu M, Ma A, Liang B, Xu W, Fan J, Zhou H, Ke A, Shen Y
Cell reports. Medicine 2025 Jul 15;6(7):102208
Cell reports. Medicine 2025 Jul 15;6(7):102208
K542 acetylation promotes YTHDF2 binding to m6A-modified mRNAs and fosters colorectal cancer progression.
Wen B, Feng S, Bao L, Li S, Yang Y, Long S, Xiao J, Li S, Hou Y, Liu S
Experimental cell research 2025 Jul 15;450(2):114667
Experimental cell research 2025 Jul 15;450(2):114667
Programmed cell death-related gene IL20RA facilitates tumor progression and remodels tumor microenvironment in thyroid cancer.
Wang Y, Zhang Y, Liu M, Liu Y, Zeng Y, Zhang W, Wu S, Hu L, Ruan X, Zheng X, Gao M, Zhao J
Scientific reports 2025 Jan 28;15(1):3520
Scientific reports 2025 Jan 28;15(1):3520
MYO1F positions cGAS on the plasma membrane to ensure full and functional signaling.
Wang H, Cui Z, Sun W, Yi M, Cheng Y, Zhang Y, Du Y, Pan T, Gao R, Feng L, Zeng B, Huang G, Li Y, Wang Y, Zhang CJ, He R, Wang C
Molecular cell 2025 Jan 2;85(1):150-165.e7
Molecular cell 2025 Jan 2;85(1):150-165.e7
The cystogenic effects of ouabain in autosomal dominant polycystic kidney disease require cell caveolae.
Trant J, Sanchez G, McDermott JP, Blanco G
Experimental cell research 2025 Jan 1;444(1):114356
Experimental cell research 2025 Jan 1;444(1):114356
Aspartate signalling drives lung metastasis via alternative translation.
Doglioni G, Fernández-García J, Igelmann S, Altea-Manzano P, Blomme A, La Rovere R, Liu XZ, Liu Y, Tricot T, Nobis M, An N, Leclercq M, El Kharraz S, Karras P, Hsieh YH, Solari FA, Martins Nascentes Melo L, Allies G, Scopelliti A, Rossi M, Vermeire I, Broekaert D, Ferreira Campos AM, Neven P, Maetens M, Van Baelen K, Alkan HF, Planque M, Floris G, Sickmann A, Tasdogan A, Marine JC, Scheele CLGJ, Desmedt C, Bultynck G, Close P, Fendt SM
Nature 2025 Feb;638(8049):244-250
Nature 2025 Feb;638(8049):244-250
AFP shields hepatocellular carcinoma from macrophage phagocytosis by regulating HuR-mediated CD47 translocation in cellular membrane.
Pan Y, Yin Q, Wang Z, Wu G, Liu K, Li X, Liu J, Zeng J, Lin B, Li W, Zhu M, Li M
Translational oncology 2025 Feb;52:102240
Translational oncology 2025 Feb;52:102240
VANGL2 alleviates inflammatory bowel disease by recruiting the ubiquitin ligase MARCH8 to limit NLRP3 inflammasome activation through OPTN-mediated selective autophagy.
Jiang H, Xie Y, Hu Z, Lu J, Zhang J, Li H, Zeng K, Peng W, Yang C, Huang J, Han Z, Bai X, Yu X
PLoS biology 2025 Feb;23(2):e3002961
PLoS biology 2025 Feb;23(2):e3002961
High-resolution spatially resolved proteomics of complex tissues based on microfluidics and transfer learning.
Hu B, He R, Pang K, Wang G, Wang N, Zhu W, Sui X, Teng H, Liu T, Zhu J, Jiang Z, Zhang J, Zuo Z, Wang W, Ji P, Zhao F
Cell 2025 Feb 6;188(3):734-748.e22
Cell 2025 Feb 6;188(3):734-748.e22
A Granzyme B-Cleavable T Cell-Targeted Bispecific Cell Vesicle Connector for Reversing New-Onset Type 1 Diabetes.
Wang Y, Sun Y, Zhang X, Wang S, Huang X, Xu K, Liu Y, Huang Y, Xu J, Wei X, Cheng H, Pan L, Wang J, Gu Z
Journal of the American Chemical Society 2025 Feb 5;147(5):4167-4179
Journal of the American Chemical Society 2025 Feb 5;147(5):4167-4179
Alpha4 Na,K-ATPase Localization and Expression Are Dynamic Aspects of Spermatogenesis and in Sperm Incubated Under Capacitating Conditions.
Milewski D, James PF
International journal of molecular sciences 2025 Feb 20;26(5)
International journal of molecular sciences 2025 Feb 20;26(5)
The sperm specific Na (+) ,K (+) -ATPase α4 shows a highly structured and dynamic distribution at the sperm flagellum.
Oishee MJ, McDermott JP, Sánchez G, Blanco G
bioRxiv : the preprint server for biology 2025 Feb 16;
bioRxiv : the preprint server for biology 2025 Feb 16;
G-protein coupled receptor kinase 2 mediates rheumatoid arthritis-induced depression-like behaviors via the hippocampal CRHR1 signaling pathway.
Meng Q, Guo MH, Zhang R, Wei J, Chen Q, Zhao XC, Xu CQ, Wu YY, Kuai JJ, Zhao JM, Wu YJ, Ye CH, Wei HR, Zhu X, Jin Y, Zhang Z, Wei W
Acta pharmacologica Sinica 2025 Dec;46(12):3177-3189
Acta pharmacologica Sinica 2025 Dec;46(12):3177-3189
Sigma1 inhibitor suppression of adaptive immune resistance mechanisms mediated by cancer cell derived extracellular vesicles.
Castagnino PA, Haas DA, Musante L, Tancler NA, Tran BV, Kean R, Steck AR, Martinez LA, Mostaghel EA, Hooper DC, Kim FJ
Cancer biology & therapy 2025 Dec;26(1):2455722
Cancer biology & therapy 2025 Dec;26(1):2455722
Norepinephrine Induces Sertoli Cell Ferroptosis via Receptors Desensitization Causing Stress-Related Male Reproductive Dysfunction.
Zhang L, Gao S, Xiong X, Liu X, Li R, Wang X, Han L, Xiao X, Wang X, Li W, Chang Y, Du Y, Yang J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(48):e04817
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(48):e04817
Vinburnine Sensitizes Radiotherapy Efficacy in Nasopharyngeal Carcinoma by Triggering Pyroptosis and Immune Responses via Activation of EDAR-NFκB Pathway.
Chen J, Liu N, Tao Q, Wu J, Huang J, Lu C, Li Q, Shen L, Chen X, Peng C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(46):e06139
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(46):e06139
Semenogelin I-derived peptide SgI-52 binds membrane Peroxiredoxin 6 and induces oxidative stress in asthenozoospermic sperm.
Yang Y, Lu C, Wu Z, Gao H, Li H, Deng R, Li X, He D, Zhao H
Reproductive biology and endocrinology : RB&E 2025 Dec 30;24(1):14
Reproductive biology and endocrinology : RB&E 2025 Dec 30;24(1):14
Membrane dome-based regulation mechanism of the mechanosensitive PIEZO channel.
Liu Y, Liu B, Zhan W, Zhang L, Shi A, Lin L, Jiang M, Guo YR
Cell reports 2025 Dec 23;44(12):116651
Cell reports 2025 Dec 23;44(12):116651
Sestrin 2 Regulates Milk Protein Synthesis through a LAT1/mTOR Pathway.
Ke Y, Chen B, Wang X, Jiang X, Liu T, Pan Y, Li Y, Song C, Chen X, Fang X, Wang Y, Zhang C
Journal of agricultural and food chemistry 2025 Dec 17;73(50):31783-31793
Journal of agricultural and food chemistry 2025 Dec 17;73(50):31783-31793
Pathogenic Mechanism of the KCNQ4 Gene Variant in Hearing Loss and Functional Validation in a Zebrafish Model.
Jia H, Liu X, Chen H, Wang Y, Guan MX, Guo Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Dec 15;39(23):e71274
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Dec 15;39(23):e71274
The fatty acid receptor CD36 promotes macrophage infiltration via p110γ signaling to stimulate metastasis.
Qin H, Xiao A, Lu Q, Li Y, Luo X, Zheng E, Tian C, Liu H, Zheng X, Wei L, Ruan XZ, Yang P, Chen Y
Journal of advanced research 2025 Aug;74:237-253
Journal of advanced research 2025 Aug;74:237-253
P5CS deacetylation mediated by SIRT2 facilitates tumor growth by enhancing mitochondrial respiration in hepatocellular carcinoma.
Geng X, Li M, Zhang L, Cai Y, Chen X, Mu X, Wang J, Liu B
Oncogene 2025 Aug;44(31):2746-2761
Oncogene 2025 Aug;44(31):2746-2761
Molecular mechanism for the interaction of MOG1 with the intracellular loop II of cardiac sodium channel Na(v)1.5 and its role in arrhythmias.
Bai X, Wang Z, Xiong H, Yan C, Yao Y, Xu C, Li H, Wang QK
Journal of molecular and cellular cardiology 2025 Aug;205:68-83
Journal of molecular and cellular cardiology 2025 Aug;205:68-83
The role of FLVCR1 and FLVCR2 in choline transport in the Caco-2 intestinal epithelial cell model and rat small intestine.
Yasujima T, Namba C, Azuma Y, Shinoda Y, Matake I, Yamasaki M, Morimoto H, Namai M, Kusuhara H, Inoue K, Yamashiro T, Yuasa H
Biochimica et biophysica acta. Molecular basis of disease 2025 Aug;1871(6):167883
Biochimica et biophysica acta. Molecular basis of disease 2025 Aug;1871(6):167883
LAPTM5 confers cisplatin resistance in NSCLC by suppressing LAMP1 ubiquitination to stabilize lysosomal membranes and sustain autophagic flux.
Wu F, Li C, Song X, Xie L
Cellular signalling 2025 Aug;132:111834
Cellular signalling 2025 Aug;132:111834
Cardiopulmonary Bypass-Induced IL-17A Aggravates Caspase-12-Dependent Neuronal Apoptosis Through the Act1-IRE1-JNK1 Pathway.
Zhao R, Ma Y, Li S, Li J
Biomolecules 2025 Aug 6;15(8)
Biomolecules 2025 Aug 6;15(8)
Biomimetic magnetobacterial microrobots for active pneumonia therapy.
Zhang L, Chen Z, Ran H, Azechi M, Yang X, Huang W, Tian H, Shen L, Peng F, Tu Y
Nature communications 2025 Aug 22;16(1):7856
Nature communications 2025 Aug 22;16(1):7856
Effects of Cholesterol Metabolism on Corneal Endothelial Dysfunction in Patients With Type 1 Diabetes.
Ren Z, Li Z, Dou S, Zhao H, Xie L
Investigative ophthalmology & visual science 2025 Aug 1;66(11):9
Investigative ophthalmology & visual science 2025 Aug 1;66(11):9
Neutrophil-like cell membrane-coated metal-organic frameworks for siRNA delivery targeting NOX4 to alleviate oxidative stress in acute ischemic injury.
Wang M, Wang Y, Zhang P, Gu C, Zhao X, Gong X, Yang X, Pan J, Xi Y
Acta biomaterialia 2025 Apr;196:487-505
Acta biomaterialia 2025 Apr;196:487-505
MLKL activity requires a splicing-regulated, druggable intramolecular interaction.
Ros U, Martinez-Osorio V, Valiente PA, Abdelwahab Y, Gojkovic M, Shalaby R, Zanna S, Saggau J, Wachsmuth L, Nemade HN, Zoeller J, Lottermoser H, Chen YG, Ibrahim M, Kelepouras K, Vasilikos L, Bedoya P, Espiritu RA, Müller S, Altmannova V, Tieleman DP, Weir J, Langer J, Adam M, Walczak H, Wong WW, Liccardi G, Mollenhauer M, Pasparakis M, Peltzer N, García-Sáez AJ
Molecular cell 2025 Apr 17;85(8):1589-1605.e12
Molecular cell 2025 Apr 17;85(8):1589-1605.e12
HSP105 inhibition downregulates store-operated calcium entry and promotes acute UVB-induced tight junction disruption.
Zhou K, Luo S, Wang Q, Ye Q, Fang S
PloS one 2024;19(12):e0314816
PloS one 2024;19(12):e0314816
Intercellular adhesion molecule-1 suppresses TMZ chemosensitivity in acquired TMZ-resistant gliomas by increasing assembly of ABCB1 on the membrane.
Zhang X, Tan Y, Li T, Tan D, Fu B, Yang M, Chen Y, Cao M, Xuan C, Du Q, Hu R, Wang Q
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2024 Sep;76:101112
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2024 Sep;76:101112
Biomimetic nanomedicine cocktail enables selective cell targeting to enhance ovarian Cancer chemo- and immunotherapy.
Dong Z, Yang W, Zhang Y, Wang B, Wan X, Li M, Chen Y, Zhang N
Journal of controlled release : official journal of the Controlled Release Society 2024 Sep;373:172-188
Journal of controlled release : official journal of the Controlled Release Society 2024 Sep;373:172-188
Inhibition of GSK3α,β rescues cognitive phenotypes in a preclinical mouse model of CTNNB1 syndrome.
Alexander JM, Vazquez-Ramirez L, Lin C, Antonoudiou P, Maguire J, Wagner F, Jacob MH
EMBO molecular medicine 2024 Sep;16(9):2109-2131
EMBO molecular medicine 2024 Sep;16(9):2109-2131
Novel Dual PPAR δ/γ Partial Agonist Induces Hepatic Lipid Accumulation through Direct Binding and Inhibition of AKT1 Phosphorylation, Mediating CD36 Upregulation.
Cai X, Zhang Q, Wang J, Miao Y, Sun Y, Xia Z, Zhang L, Yu Q, Jiang Z
Chemical research in toxicology 2024 Sep 16;37(9):1574-1587
Chemical research in toxicology 2024 Sep 16;37(9):1574-1587
Deficiency of geranylgeranyl biphosphate synthase in kidney tubules causes cystic kidney disease.
Shao X, Wang K, Wu J, Ma X, Zhao Y, Xu T, Dai C, Zhang F, Wang Y, Ren X, Lu K, Yin Z, Guo B, Cao C, Xu X, Xue B
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Sep 15;38(17):e23875
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Sep 15;38(17):e23875
TMC7 deficiency causes acrosome biogenesis defects and male infertility in mice.
Wang J, Yin Y, Yang L, Qin J, Wang Z, Qiu C, Gao Y, Lu G, Gao F, Chen ZJ, Zhang X, Liu H, Liu Z
eLife 2024 Sep 13;13
eLife 2024 Sep 13;13
Scavenger Receptor Class B Type I Modulates Epileptic Seizures and Receptor α2δ-1 Expression.
Huang Y, Gao Y, Huang Z, Liang M, Chen Y
Neurochemical research 2024 Oct;49(10):2842-2853
Neurochemical research 2024 Oct;49(10):2842-2853
Nrf2 deficiency exacerbated pulmonary pyroptosis in maternal hypoxia-induced intrauterine growth restriction offspring mice.
Chen D, Man LY, Wang YY, Zhu WY, Zhao HM, Li SP, Zhang YL, Li SC, Wu YX, Ling-Ai, Pang QF
Reproductive toxicology (Elmsford, N.Y.) 2024 Oct;129:108671
Reproductive toxicology (Elmsford, N.Y.) 2024 Oct;129:108671
Astrocyte-derived lactoferrin inhibits neuronal ferroptosis by reducing iron content and GPX4 degradation in APP/PS1 transgenic mice.
Fan YG, Ge RL, Ren H, Jia RJ, Wu TY, Lei XF, Wu Z, Zhou XB, Wang ZY
Pharmacological research 2024 Nov;209:107404
Pharmacological research 2024 Nov;209:107404
Structural insights into the mechanisms of urea permeation and distinct inhibition modes of urea transporters.
Huang SM, Huang ZZ, Liu L, Xiong MY, Zhang C, Cai BY, Wang MW, Cai K, Jia YL, Wang JL, Zhang MH, Xie YH, Li M, Zhang H, Weng CH, Wen X, Li Z, Sun Y, Yi F, Yang Z, Xiao P, Yang F, Yu X, Tie L, Yang BX, Sun JP
Nature communications 2024 Nov 26;15(1):10226
Nature communications 2024 Nov 26;15(1):10226
Hepatocyte-derived Fetuin-A promotes alcohol-associated liver disease in mice by inhibiting autophagy-lysosome degradation of TLR and M2 macrophage polarization.
Lu S, Jin H, Nong T, Li D, Long K, Chen Y, Li Y, Xing H, Pan T, He S, Jiang K, Zhong F
Free radical biology & medicine 2024 Nov 1;224:506-520
Free radical biology & medicine 2024 Nov 1;224:506-520
Stevioside Ameliorates Palmitic Acid-Induced Abnormal Glucose Uptake via the PDK4/AMPK/TBC1D1 Pathway in C2C12 Myotubes.
Zhang C, Li S, Li L, Wang R, Luo S, Li G
Endocrinology, diabetes & metabolism 2024 May;7(3):e00482
Endocrinology, diabetes & metabolism 2024 May;7(3):e00482
p53 suppresses the inflammatory response following respiratory syncytial virus infection by inhibiting TLR2.
Liu J, Gao L, Zhou N, Jiang Z, Che S, Deng Y, Zang N, Ren L, Xie X, Xie J, Liu E
Virology 2024 May;593:110018
Virology 2024 May;593:110018
Ultrasound Imaging of Tumor Vascular CD93 with MMRN2 Modified Microbubbles for Immune Microenvironment Prediction.
Wang D, Xing C, Liang Y, Wang C, Zhao P, Liang X, Li Q, Yuan L
Advanced materials (Deerfield Beach, Fla.) 2024 May;36(18):e2310421
Advanced materials (Deerfield Beach, Fla.) 2024 May;36(18):e2310421
Targeting osteopontin alleviates endometriosis and inflammation by inhibiting the RhoA/ROS axis and achieves non-invasive in vitro detection via menstrual blood.
Wang H, Wang B, Wu M, Lu J, Duan P
Human reproduction (Oxford, England) 2024 May 2;39(5):1057-1071
Human reproduction (Oxford, England) 2024 May 2;39(5):1057-1071
Knockdown of trem2 promotes proinflammatory microglia and inhibits glioma progression via the JAK2/STAT3 and NF-κB pathways.
Yan Y, Bai S, Han H, Dai J, Niu L, Wang H, Dong Q, Yin H, Yuan G, Pan Y
Cell communication and signaling : CCS 2024 May 15;22(1):272
Cell communication and signaling : CCS 2024 May 15;22(1):272
6-Gingerol alleviates ectopic lipid deposition in skeletal muscle by regulating CD36 translocation and mitochondrial function.
Peng Z, Zeng Y, Tan Q, He Q, Wang S, Wang J
Biochemical and biophysical research communications 2024 May 14;708:149786
Biochemical and biophysical research communications 2024 May 14;708:149786
PEBP4 deficiency aggravates LPS-induced acute lung injury and alveolar fluid clearance impairment via modulating PI3K/AKT signaling pathway.
Shi QQ, Huang YH, Li YF, Zhen SY, Li YH, Huang JY, Wang JY, Zhou XY
Cellular and molecular life sciences : CMLS 2024 Mar 13;81(1):133
Cellular and molecular life sciences : CMLS 2024 Mar 13;81(1):133
Disruption of the Na(+)/K(+)-ATPase-purinergic P2X7 receptor complex in microglia promotes stress-induced anxiety.
Huang S, Dong W, Lin X, Xu K, Li K, Xiong S, Wang Z, Nie X, Bian JS
Immunity 2024 Mar 12;57(3):495-512.e11
Immunity 2024 Mar 12;57(3):495-512.e11
SCN5A-L256del and L1621F exhibit loss-of-function properties related to autosomal recessive congenital cardiac disorders presenting as sick sinus syndrome, dilated cardiomyopathy, and sudden cardiac death.
Shi J, Pan X, Wang Z, Yi M, Xie S, Zhang X, Tao D, Yang Y, Liu Y
Gene 2024 Mar 10;898:148093
Gene 2024 Mar 10;898:148093
Neutrophil-derived nanovesicles deliver IL-37 to mitigate renal ischemia-reperfusion injury via endothelial cell targeting.
Ma W, Wu D, Long C, Liu J, Xu L, Zhou L, Dou Q, Ge Y, Zhou C, Jia R
Journal of controlled release : official journal of the Controlled Release Society 2024 Jun;370:66-81
Journal of controlled release : official journal of the Controlled Release Society 2024 Jun;370:66-81
Signature identification based on immunogenic cell death-related lncRNAs to predict the prognosis and immune activity of patients with endometrial carcinoma.
Yao Y, Zhang Q, Wei S, Li H, Zhou T, Zhang Q, Zhang J, Zhang J, Wang H
Translational cancer research 2024 Jun 30;13(6):2913-2937
Translational cancer research 2024 Jun 30;13(6):2913-2937
Impact of RAAS Receptors and Membrane-Bound Transporter System in the Left Ventricle during the Long-Term Control of Hypertension.
Swami Vetha BS, Byrum R, Mebane D, Katwa LC, Aileru A
International journal of molecular sciences 2024 Jun 26;25(13)
International journal of molecular sciences 2024 Jun 26;25(13)
Homeostatic coordination of cellular phosphate uptake and efflux requires an organelle-based receptor for the inositol pyrophosphate IP8.
Li X, Kirkpatrick RB, Wang X, Tucker CJ, Shukla A, Jessen HJ, Wang H, Shears SB, Gu C
Cell reports 2024 Jun 25;43(6):114316
Cell reports 2024 Jun 25;43(6):114316
Acetylation of ELMO1 correlates with Rac1 activity and colorectal cancer progress.
Li C, Yi J, Jie H, Liu Z, Li S, Zeng Z, Zhou Y
Experimental cell research 2024 Jun 1;439(1):114068
Experimental cell research 2024 Jun 1;439(1):114068
Noncoding RNA regulates the expression of Krm1 and Dkk2 to synergistically affect aortic valve lesions.
Xian G, Huang R, Xu M, Zhao H, Xu X, Chen Y, Ren H, Xu D, Zeng Q
Experimental & molecular medicine 2024 Jul;56(7):1560-1573
Experimental & molecular medicine 2024 Jul;56(7):1560-1573
Membranal Expression of Calreticulin Induced by Unfolded Protein Response in Melanocytes: A Mechanism Underlying Oxidative Stress-Induced Autoimmunity in Vitiligo.
Song P, Zhang W, Guo S, Wang G, Gao T, Li C, Liu L
The Journal of investigative dermatology 2024 Jul;144(7):1622-1632.e5
The Journal of investigative dermatology 2024 Jul;144(7):1622-1632.e5
Ultrasound-responsive Bi(2)MoO(6)-MXene heterojunction as ferroptosis inducers for stimulating immunogenic cell death against ovarian cancer.
Cheng S, Zhou T, Luo Y, Zhang J, Dong K, Zhang Q, Shu W, Zhang T, Zhang Q, Shi R, Yao Y, Wang H
Journal of nanobiotechnology 2024 Jul 11;22(1):408
Journal of nanobiotechnology 2024 Jul 11;22(1):408
Human Kidney Proximal Tubule-Microvascular Model Facilitates High-Throughput Analyses of Structural and Functional Effects of Ischemia-Reperfusion Injury.
Shaughnessey EM, Kann SH, Charest JL, Vedula EM
Advanced biology 2024 Jan;8(1):e2300127
Advanced biology 2024 Jan;8(1):e2300127
Hyaluronan delays human amniotic epithelial stem cell senescence by regulating CD44 isoform switch to activate AKT/mTOR signals.
Yu C, Yuan H, Xu Y, Luo Y, Wu ZH, Zhong JJ, Xiao JH
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jan;170:116100
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jan;170:116100
Biomimetic Nanomedicine Targeting Orchestrated Metabolism Coupled with Regulatory Factors to Disrupt the Metabolic Plasticity of Breast Cancer.
Meng L, Yang J, Gao Y, Cao Q, Jiang S, Xiao Y, Wang H, Liu W, Yuan A, Li Y, Huang H
ACS nano 2024 Feb 6;18(5):4360-4375
ACS nano 2024 Feb 6;18(5):4360-4375
Deleting IP6K1 stabilizes neuronal sodium-potassium pumps and suppresses excitability.
Jin H, Liu A, Chin AC, Fu C, Shen H, Cheng W
Molecular brain 2024 Feb 13;17(1):8
Molecular brain 2024 Feb 13;17(1):8
Optimization of Cell Membrane Purification for the Preparation and Characterization of Cell Membrane Liposomes.
de Weerd S, Ruiter EA, Calicchia E, Portale G, Schuringa JJ, Roos WH, Salvati A
Small methods 2024 Dec;8(12):e2400498
Small methods 2024 Dec;8(12):e2400498
Targeting overexpressed antigens in glioblastoma via CAR T cells with computationally designed high-affinity protein binders.
Xia Z, Jin Q, Long Z, He Y, Liu F, Sun C, Liao J, Wang C, Wang C, Zheng J, Zhao W, Zhang T, Rich JN, Zhang Y, Cao L, Xie Q
Nature biomedical engineering 2024 Dec;8(12):1634-1650
Nature biomedical engineering 2024 Dec;8(12):1634-1650
Annexin-A1 tripeptide enhances functional recovery and mitigates brain damage in traumatic brain injury by inhibiting neuroinflammation and preventing ANXA1 nuclear translocation in mice.
Lin K, Hou Y, Li R, Fan F, Hao Y, Wang Y, Huang Y, Li P, Zhu L, Huang X, Zhao YQ
Metabolic brain disease 2024 Dec;39(8):1559-1571
Metabolic brain disease 2024 Dec;39(8):1559-1571
A Homozygous Variant in NAA60 Is Associated with Primary Familial Brain Calcification.
Chen X, Shi Y, Fu F, Wang L, Yu H, Yang D, Wang X, Ying C, Wang H, Lin Z, Wang H, Zhang F, Zheng X, Guo Y, Wang Y, Zeng Y, Zhao M, Chen Y, Li J, Xia H, Chen J, Wang B, Wu S, Xie F, Feng J, Cen Z, Luo W
Movement disorders : official journal of the Movement Disorder Society 2024 Dec;39(12):2190-2198
Movement disorders : official journal of the Movement Disorder Society 2024 Dec;39(12):2190-2198
SEMA7A-mediated juxtacrine stimulation of IGFBP-3 upregulates IL-17RB at pancreatic cancer invasive front.
Chen YI, Tien SC, Ko YL, Chang CC, Hsu MF, Chien HJ, Peng HY, Jeng YM, Tien YW, Chang YT, Chang MC, Hu CM
Cancer gene therapy 2024 Dec;31(12):1840-1855
Cancer gene therapy 2024 Dec;31(12):1840-1855
Melanocortin 1 receptor mediates melanin production by interacting with the BBSome in primary cilia.
Tian X, Wang H, Liu S, Liu W, Zhang K, Gao X, Li Q, Zhao H, Zhang L, Liu P, Liu M, Wang Y, Zhu X, Cui R, Zhou J
PLoS biology 2024 Dec;22(12):e3002940
PLoS biology 2024 Dec;22(12):e3002940
Febuxostat enhances the efficacy of dasatinib by inhibiting ATP-binding cassette subfamily G member 2 (ABCG2) in chronic myeloid leukemia cells.
Kawashima K, Ikemura K, Takemura M, Toyozumi Y, Okuda M
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Dec;181:117709
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Dec;181:117709
Artemisitene induces apoptosis of breast cancer cells by targeting FDFT1 and inhibits the growth of breast cancer patient-derived organoids.
Chen D, Li G, Luo L, Lin T, Chu X, Liu K, Lai T, Liao Y, Lin X, Chen J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156155
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156155
Dual-Functional Nanodroplet for Tumor Vasculature Ultrasound Imaging and Tumor Immunosuppressive Microenvironment Remodeling.
Liang Y, Zhang S, Wang D, Ji P, Zhang B, Wu P, Wang L, Liu Z, Wang J, Duan Y, Yuan L
Advanced healthcare materials 2024 Dec;13(31):e2401274
Advanced healthcare materials 2024 Dec;13(31):e2401274
Subcellular Proteomic Mapping of Lysine Lactylation.
Bao Q, Wan N, He Z, Cao J, Yuan W, Hao H, Ye H
Journal of the American Society for Mass Spectrometry 2024 Dec 4;35(12):3221-3232
Journal of the American Society for Mass Spectrometry 2024 Dec 4;35(12):3221-3232
GPR37-enhanced ubiquitination of ATP1A1 inhibits tumor progression and radiation resistance in esophageal squamous cell carcinoma.
Hu J, Meng F, Lv L, Hong F, He Q, Zhu Q, Tian T, Chang N, Zhang S, Yi Q, Qian L
Cell death & disease 2024 Dec 27;15(12):933
Cell death & disease 2024 Dec 27;15(12):933
The classical D1 dopamine receptor antagonist SCH23390 is a functional sigma-1 receptor allosteric modulator.
Zhang GF, Zhu KL, Li Q, Zhang Y, Waddington JL, Du XD, Zhen XC
Acta pharmacologica Sinica 2024 Aug;45(8):1582-1590
Acta pharmacologica Sinica 2024 Aug;45(8):1582-1590
ATG5-mediated keratinocyte ferroptosis promotes M1 polarization of macrophages to aggravate UVB-induced skin inflammation.
Xiao T, Liang J, Li M, Guo Y, Chen S, Ke Y, Gao X, Gu H, Chen X
Journal of photochemistry and photobiology. B, Biology 2024 Aug;257:112948
Journal of photochemistry and photobiology. B, Biology 2024 Aug;257:112948
Cancer cell membrane-camouflaged paclitaxel/PLGA nanoparticles for targeted therapy against lung cancer.
Zhou J, Wan S, Wu Y, Hu H, Liu Y, Liao Z, Xu M, Wu J, Fan Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Aug;177:117102
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Aug;177:117102
Postsynaptic lncRNA Sera/Pkm2 pathway orchestrates the transition from social competition to rank by remodeling the neural ensemble in mPFC.
Zhu LS, Lai C, Zhou CW, Chen HY, Liu ZQ, Guo Z, Man H, Du HY, Lu Y, Hu F, Chen Z, Shu K, Zhu LQ, Liu D
Cell discovery 2024 Aug 20;10(1):87
Cell discovery 2024 Aug 20;10(1):87
Extract of Phyllanthus emblica L. fruit stimulates basal glucose uptake and ameliorates palmitate-induced insulin resistance through AMPK activation in C2C12 myotubes.
Li HY, Li CF, Liu CH, Chen SC, Liu YF, Lv QH, Zhang W
BMC complementary medicine and therapies 2024 Aug 2;24(1):296
BMC complementary medicine and therapies 2024 Aug 2;24(1):296
Therapeutic application of extracellular vesicular EGFR isoform D as a co-drug to target squamous cell cancers with tyrosine kinase inhibitors.
Toh SY, Leong HS, Chong FT, Rodrigues-Junior DM, Ren MJ, Kwang XL, Lau DPX, Lee PH, Vettore AL, Teh BT, Tan DSW, Iyer NG
Developmental cell 2024 Aug 19;59(16):2189-2202.e8
Developmental cell 2024 Aug 19;59(16):2189-2202.e8
Membranous translocation of murine double minute 2 promotes the increased renal tubular immunogenicity in ischemia-reperfusion-induced acute kidney injury.
Zeng J, Ye C, Zhang C, Su H
American journal of physiology. Renal physiology 2024 Aug 1;327(2):F290-F303
American journal of physiology. Renal physiology 2024 Aug 1;327(2):F290-F303
GDNF improves the cognitive ability of PD mice by promoting glycosylation and membrane distribution of DAT.
Chengcheng M, Panpan A, Yalong Y, Mingyu S, Wei X, Jing C, Chuanxi T
Scientific reports 2024 Aug 1;14(1):17845
Scientific reports 2024 Aug 1;14(1):17845
The Lipophilic Extract from Ginkgo biloba L. Leaves Promotes Glucose Uptake and Alleviates Palmitate-Induced Insulin Resistance in C2C12 Myotubes.
Li T, Lv Q, Liu C, Li C, Xie X, Zhang W
Molecules (Basel, Switzerland) 2024 Apr 3;29(7)
Molecules (Basel, Switzerland) 2024 Apr 3;29(7)
K48-linked deubiquitination of VGLL4 by USP15 enhances the efficacy of tumor immunotherapy in triple-negative breast cancer.
Wang X, Deng X, Hu J, Zheng W, Ye D, Zhou X, Fang L
Cancer letters 2024 Apr 28;588:216764
Cancer letters 2024 Apr 28;588:216764
CAV3 alleviates diabetic cardiomyopathy via inhibiting NDUFA10-mediated mitochondrial dysfunction.
Guo P, Hu S, Liu X, He M, Li J, Ma T, Huang M, Fang Q, Wang Y
Journal of translational medicine 2024 Apr 26;22(1):390
Journal of translational medicine 2024 Apr 26;22(1):390
Nerve Growth Factor/Tyrosine Kinase A Receptor Pathway Enhances Analgesia in an Experimental Mouse Model of Bone Cancer Pain by Increasing Membrane Levels of δ-Opioid Receptors.
Kan BF, Liu XY, Han MM, Yang CW, Zhu X, Jin Y, Wang D, Huang X, Wu WJ, Fu T, Kang F, Zhang Z, Li J
Anesthesiology 2024 Apr 1;140(4):765-785
Anesthesiology 2024 Apr 1;140(4):765-785
Effects of frog skin peptide temporin-1CEa and its analogs on ox-LDL induced macrophage-derived foam cells.
Yang XF, Liu X, Yan XY, Shang DJ
Frontiers in pharmacology 2023;14:1139532
Frontiers in pharmacology 2023;14:1139532
WT1(+) glomerular parietal epithelial progenitors promote renal proximal tubule regeneration after severe acute kidney injury.
Hong X, Nie H, Deng J, Liang S, Chen L, Li J, Gong S, Wang G, Zuo W, Hou F, Zhang F
Theranostics 2023;13(4):1311-1324
Theranostics 2023;13(4):1311-1324
Stiff matrix induced srGAP2 tension gradients control migration direction in triple-negative breast cancer.
Li C, Zheng Z, Wu X, Xie Q, Liu P, Hu Y, Chen M, Liu L, Zhao W, Chen L, Guo J, Song Y
Theranostics 2023;13(1):59-76
Theranostics 2023;13(1):59-76
Telaprevir Improves Memory and Cognition in Mice Suffering Ischemic Stroke via Targeting MALT1-Mediated Calcium Overload and Necroptosis.
Zhang YY, Peng JJ, Chen D, Liu HQ, Yao BF, Peng J, Luo XJ
ACS chemical neuroscience 2023 Sep 6;14(17):3113-3124
ACS chemical neuroscience 2023 Sep 6;14(17):3113-3124
HSP90B1-mediated plasma membrane localization of GLUT1 promotes radioresistance of glioblastomas.
Li Y, Ge Y, Zhao M, Ding F, Wang X, Shi Z, Ge X, Wang X, Qian X
Journal of biomedical research 2023 Sep 28;37(5):326-339
Journal of biomedical research 2023 Sep 28;37(5):326-339
FAT4 overexpression promotes antitumor immunity by regulating the β-catenin/STT3/PD-L1 axis in cervical cancer.
Wang D, Wu S, He J, Sun L, Zhu H, Zhang Y, Liu S, Duan X, Wang Y, Xu T
Journal of experimental & clinical cancer research : CR 2023 Sep 1;42(1):222
Journal of experimental & clinical cancer research : CR 2023 Sep 1;42(1):222
Liang-Ge-San inhibits dengue virus serotype 2 infection by reducing caveolin1-induced cytoplasmic heat shock protein 70 translocation into the plasma membrane.
Chen X, Yang JB, Cao HH, Fang XC, Liu SH, Zou LF, Yu JH, Zuo JP, Zhao W, Lu ZB, Liu JS, Yu LZ
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Oct;119:154977
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Oct;119:154977
Neuroplastin exerts antiepileptic effects through binding to the α1 subunit of GABA type A receptors to inhibit the internalization of the receptors.
Li S, Wei X, Huang H, Ye L, Ma M, Sun L, Lu Y, Wu Y
Journal of translational medicine 2023 Oct 9;21(1):707
Journal of translational medicine 2023 Oct 9;21(1):707
STIM2 regulates NMDA receptor endocytosis that is induced by short-term NMDA receptor overactivation in cortical neurons.
Serwach K, Nurowska E, Klukowska M, Zablocka B, Gruszczynska-Biegala J
Cellular and molecular life sciences : CMLS 2023 Nov 21;80(12):368
Cellular and molecular life sciences : CMLS 2023 Nov 21;80(12):368
Meta-data analysis of kidney stone disease highlights ATP1A1 involvement in renal crystal formation.
Li Y, Lu X, Yu Z, Wang H, Gao B
Redox biology 2023 May;61:102648
Redox biology 2023 May;61:102648
Cell membrane derived liposomes loaded with DNase I target neutrophil extracellular traps which inhibits colorectal cancer liver metastases.
Wang Z, Chen C, Shi C, Zhao X, Gao L, Guo F, Han M, Yang Z, Zhang J, Tang C, Zhang C, Liu Y, Sun P, Jiang X
Journal of controlled release : official journal of the Controlled Release Society 2023 May;357:620-629
Journal of controlled release : official journal of the Controlled Release Society 2023 May;357:620-629
Novel secreted STPKLRR from Vibrio splendidus AJ01 promotes pathogen internalization via mediating tropomodulin phosphorylation dependent cytoskeleton rearrangement.
Dai F, Guo M, Shao Y, Li C
PLoS pathogens 2023 May;19(5):e1011419
PLoS pathogens 2023 May;19(5):e1011419
The Bacillus cereus toxin alveolysin disrupts the intestinal epithelial barrier by inducing microtubule disorganization through CFAP100.
Sun S, Xu Z, Hu H, Zheng M, Zhang L, Xie W, Sun L, Liu P, Li T, Zhang L, Chen M, Zhu X, Liu M, Yang Y, Zhou J
Science signaling 2023 May 16;16(785):eade8111
Science signaling 2023 May 16;16(785):eade8111
The Weakened Interaction Between HECTD4 and GluN2B in Ischemic Stroke Promotes Calcium Overload and Brain Injury Through a Mechanism Involving the Decrease of GluN2B and MALT1 Ubiquitination.
Zhang YY, Yang XY, Liu HQ, Zhang Z, Hu CP, Peng J, Luo XJ
Molecular neurobiology 2023 Mar;60(3):1563-1579
Molecular neurobiology 2023 Mar;60(3):1563-1579
Lysosomal control of senescence and inflammation through cholesterol partitioning.
Roh K, Noh J, Kim Y, Jang Y, Kim J, Choi H, Lee Y, Ji M, Kang D, Kim MS, Paik MJ, Chung J, Kim JH, Kang C
Nature metabolism 2023 Mar;5(3):398-413
Nature metabolism 2023 Mar;5(3):398-413
Activation of metabotropic glutamate receptor 1 regulates hippocampal CA1 region excitability in rats with status epilepticus by suppressing the HCN1 channel.
Luo XD, Xiang T, Li SJ, Ma MG, Chen ML, Wu Y
Neural regeneration research 2023 Mar;18(3):594-602
Neural regeneration research 2023 Mar;18(3):594-602
Identification of a novel missense SCN5A mutation in a Chinese Han family with Brugada syndrome.
Zhu J, Shen Y, Xiong H, Zha H, Zhang L, Peng H, Tian L
Biochemical and biophysical research communications 2023 Mar 15;649:55-61
Biochemical and biophysical research communications 2023 Mar 15;649:55-61
Role of the Peli1-RIPK1 Signaling Axis in Methamphetamine-Induced Neuroinflammation.
Xu W, Yang T, Lou X, Chen J, Wang X, Hu M, An D, Gao R, Wang J, Chen X
ACS chemical neuroscience 2023 Mar 1;14(5):864-874
ACS chemical neuroscience 2023 Mar 1;14(5):864-874
25-hydroxycholesterol inhibits human papillomavirus infection in cervical epithelial cells by perturbing cytoskeletal remodeling.
Li B, Hua C, Tian P, Sha Y, Zhang L, Wang Q, Lu L, Jiang S, Sui L
Journal of medical virology 2023 Jun;95(6):e28834
Journal of medical virology 2023 Jun;95(6):e28834
Activation of TLR7-mediated autophagy increases epileptic susceptibility via reduced KIF5A-dependent GABA(A) receptor transport in a murine model.
Liu J, Ke P, Guo H, Gu J, Liu Y, Tian X, Wang X, Xiao F
Experimental & molecular medicine 2023 Jun;55(6):1159-1173
Experimental & molecular medicine 2023 Jun;55(6):1159-1173
ICP4-Associated Activation of Rap1b Facilitates Herpes Simplex Virus Type I (HSV-1) Infection in Human Corneal Epithelial Cells.
Zhang B, Ding J, Ma Z
Viruses 2023 Jun 27;15(7)
Viruses 2023 Jun 27;15(7)
ZDHHC2-Mediated AGK Palmitoylation Activates AKT-mTOR Signaling to Reduce Sunitinib Sensitivity in Renal Cell Carcinoma.
Sun Y, Zhu L, Liu P, Zhang H, Guo F, Jin X
Cancer research 2023 Jun 15;83(12):2034-2051
Cancer research 2023 Jun 15;83(12):2034-2051
Ultrasound Responsive Nanovaccine Armed with Engineered Cancer Cell Membrane and RNA to Prevent Foreseeable Metastasis.
Sun W, Ji P, Zhou T, Li Z, Xing C, Zhang L, Wei M, Yang G, Yuan L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Jul;10(19):e2301107
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Jul;10(19):e2301107
Coreceptor AXL Facilitates African Swine Fever Virus Entry via Apoptotic Mimicry.
Chen X, Zheng J, Li T, Liu C, Bao M, Wang X, Li X, Li J, Huang L, Zhang Z, Weng C
Journal of virology 2023 Jul 27;97(7):e0061623
Journal of virology 2023 Jul 27;97(7):e0061623
Melatonin inhibits ferroptosis and delays age-related cataract by regulating SIRT6/p-Nrf2/GPX4 and SIRT6/NCOA4/FTH1 pathways.
Mi Y, Wei C, Sun L, Liu H, Zhang J, Luo J, Yu X, He J, Ge H, Liu P
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jan;157:114048
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jan;157:114048
Tilianin improves lipid profile and alleviates atherosclerosis in ApoE(-/-) mice through up-regulation of SREBP2-mediated LDLR expression.
Du Y, Xi M, Li Y, Zheng R, Ding X, Li X, Zhang X, Wang L, Xing J, Hong B
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jan;109:154577
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jan;109:154577
STING Suppresses Mitochondrial VDAC2 to Govern RCC Growth Independent of Innate Immunity.
Zhu Z, Zhou X, Du H, Cloer EW, Zhang J, Mei L, Wang Y, Tan X, Hepperla AJ, Simon JM, Cook JG, Major MB, Dotti G, Liu P
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Jan;10(3):e2203718
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Jan;10(3):e2203718
Disrupted in renal carcinoma 2 (DIRC2/SLC49A4) is an H(+)-driven lysosomal pyridoxine exporter.
Akino S, Yasujima T, Yamashiro T, Yuasa H
Life science alliance 2023 Feb;6(2)
Life science alliance 2023 Feb;6(2)
Negative regulation of TREM2-mediated C9orf72 poly-GA clearance by the NLRP3 inflammasome.
Shu X, Wei C, Tu WY, Zhong K, Qi S, Wang A, Bai L, Zhang SX, Luo B, Xu ZZ, Zhang K, Shen C
Cell reports 2023 Feb 28;42(2):112133
Cell reports 2023 Feb 28;42(2):112133
HERC2 promotes inflammation-driven cancer stemness and immune evasion in hepatocellular carcinoma by activating STAT3 pathway.
Liu Y, Xu Q, Deng F, Zheng Z, Luo J, Wang P, Zhou J, Lu X, Zhang L, Chen Z, Zhang Q, Chen Q, Zuo D
Journal of experimental & clinical cancer research : CR 2023 Feb 1;42(1):38
Journal of experimental & clinical cancer research : CR 2023 Feb 1;42(1):38
Dihydroartemisinin inhibits liver cancer cell migration and invasion by reducing ATP synthase production through CaMKK2/NCLX.
Chang J, Xin C, Wang Y, Wang Y
Oncology letters 2023 Dec;26(6):540
Oncology letters 2023 Dec;26(6):540
Scribble promotes fibrosis-dependent mechanisms of hepatocarcinogenesis by p53/PUMA-mediated glycolysis.
Wu Y, Song L, Kong J, Wen Q, Jiao J, Wang X, Li G, Xu X, Zhan L
Biochimica et biophysica acta. Molecular basis of disease 2023 Dec;1869(8):166823
Biochimica et biophysica acta. Molecular basis of disease 2023 Dec;1869(8):166823
Biochemical Toxicological Study of Insulin Overdose in Rats: A Forensic Perspective.
Bian C, He X, Wang Q, Zheng Z, Zhang Y, Xiong H, Li Y, Zhao M, Li J
Toxics 2023 Dec 23;12(1)
Toxics 2023 Dec 23;12(1)
Choroid plexus mast cells drive tumor-associated hydrocephalus.
Li Y, Di C, Song S, Zhang Y, Lu Y, Liao J, Lei B, Zhong J, Guo K, Zhang N, Su S
Cell 2023 Dec 21;186(26):5719-5738.e28
Cell 2023 Dec 21;186(26):5719-5738.e28
Phosphorylation of the AMPARs regulated by protein kinase C (PKC) and protein interacting with C-kinase 1 (PICK1) contribute to orofacial neuropathic pain.
Liu F, Zhang YH, Zhang YY, Lin J, Liu YJ, Li YL, Fang ZH, Liao HL, Wang H, Shen JF
Brain research 2023 Dec 1;1820:148578
Brain research 2023 Dec 1;1820:148578
Prenylated PALM2 Promotes the Migration of Esophageal Squamous Cell Carcinoma Cells Through Activating Ezrin.
Deng DX, Li CY, Zheng ZY, Wen B, Liao LD, Zhang XJ, Li EM, Xu LY
Molecular & cellular proteomics : MCP 2023 Aug;22(8):100593
Molecular & cellular proteomics : MCP 2023 Aug;22(8):100593
Environmentally relevant exposure to cypermethrin aggravates diet-induced diabetic symptoms in mice: The interaction between environmental chemicals and diet.
Wei Y, Liu W, Liu J
Environment international 2023 Aug;178:108090
Environment international 2023 Aug;178:108090
Unsaturated bond recognition leads to biased signal in a fatty acid receptor.
Mao C, Xiao P, Tao XN, Qin J, He QT, Zhang C, Guo SC, Du YQ, Chen LN, Shen DD, Yang ZS, Zhang HQ, Huang SM, He YH, Cheng J, Zhong YN, Shang P, Chen J, Zhang DL, Wang QL, Liu MX, Li GY, Guo Y, Xu HE, Wang C, Zhang C, Feng S, Yu X, Zhang Y, Sun JP
Science (New York, N.Y.) 2023 Apr 7;380(6640):eadd6220
Science (New York, N.Y.) 2023 Apr 7;380(6640):eadd6220
Golgi Phosphoprotein 3 Promotes Colon Cancer Cell Metastasis Through STAT3 and Integrin α3 Pathways.
Huang A, Wang R, Cui J, Gao Y, Yin Z, Chen L, He M, Li W
Frontiers in molecular biosciences 2022;9:808152
Frontiers in molecular biosciences 2022;9:808152
Attenuation of ROS/Chloride Efflux-Mediated NLRP3 Inflammasome Activation Contributes to Alleviation of Diabetic Cardiomyopathy in Rats after Sleeve Gastrectomy.
Li S, Dong S, Shi B, Xu Q, Li L, Wang S, Zhang W, Zhong M, Zhu J, Cheng Y, Zhang G, Hu S
Oxidative medicine and cellular longevity 2022;2022:4608914
Oxidative medicine and cellular longevity 2022;2022:4608914
A marine-derived small molecule induces immunogenic cell death against triple-negative breast cancer through ER stress-CHOP pathway.
Wen H, Zhong Y, Yin Y, Qin K, Yang L, Li D, Yu W, Yang C, Deng Z, Hong K
International journal of biological sciences 2022;18(7):2898-2913
International journal of biological sciences 2022;18(7):2898-2913
Claudin-10 overexpression suppresses human clear cell renal cell carcinoma growth and metastasis by regulating ATP5O and causing mitochondrial dysfunction.
Yang W, Zhang K, Zhang Z, Zhou J, Li L, Xu Y, Qiu J, Cai L, Gong Y, Gong K
International journal of biological sciences 2022;18(6):2329-2344
International journal of biological sciences 2022;18(6):2329-2344
Hyperinsulinemia-induced microglial mitochondrial dynamic and metabolic alterations lead to neuroinflammation in vivo and in vitro.
Yang X, Xu Y, Gao W, Wang L, Zhao X, Liu G, Fan K, Liu S, Hao H, Qu S, Dong R, Ma X, Ma J
Frontiers in neuroscience 2022;16:1036872
Frontiers in neuroscience 2022;16:1036872
Induction of A Disintegrin and Metalloproteinase with Thrombospondin motifs 1 by a rare variant or cognitive activities reduces hippocampal amyloid-β and consequent Alzheimer's disease risk.
Qiu Y, Sha L, Zhang X, Li G, Zhu W, Xu Q
Frontiers in aging neuroscience 2022;14:896522
Frontiers in aging neuroscience 2022;14:896522
Jiangtang Sanhao formula ameliorates skeletal muscle insulin resistance via regulating GLUT4 translocation in diabetic mice.
Ye Z, Ma J, Liu Y, Xu B, Dai X, Fu M, Tian T, Sui X, Mo F, Gao S, Zhao D, Zhang D
Frontiers in pharmacology 2022;13:950535
Frontiers in pharmacology 2022;13:950535
Stimulatory G-Protein α Subunit Modulates Endothelial Cell Permeability Through Regulation of Plasmalemma Vesicle-Associated Protein.
He L, Lu H, Ji X, Chu J, Qin X, Chen M, Weinstein LS, Gao J, Yang J, Zhang Q, Zhang C, Zhang W
Frontiers in pharmacology 2022;13:941064
Frontiers in pharmacology 2022;13:941064
Hepatocyte-Conditional Knockout of Phosphatidylethanolamine Binding Protein 4 Aggravated LPS/D-GalN-Induced Acute Liver Injury via the TLR4/NF-κB Pathway.
Qu XQ, Chen QF, Shi QQ, Luo QQ, Zheng SY, Li YH, Bai LY, Gan S, Zhou XY
Frontiers in immunology 2022;13:901566
Frontiers in immunology 2022;13:901566
Expression Regulation of Water Reabsorption Genes and Transcription Factors in the Kidneys of Lepus yarkandensis.
Luo S, Li Y, Li S, Jiang R, Deng F, Liu G, Zhang J
Frontiers in physiology 2022;13:856427
Frontiers in physiology 2022;13:856427
Estradiol Ameliorates Acute Kidney Ischemia-Reperfusion Injury by Inhibiting the TGF-βRI-SMAD Pathway.
Ren L, Li F, Di Z, Xiong Y, Zhang S, Ma Q, Bian X, Lang Z, Ye Q, Wang Y
Frontiers in immunology 2022;13:822604
Frontiers in immunology 2022;13:822604
Avasimibe Alleviates Disruption of the Airway Epithelial Barrier by Suppressing the Wnt/β-Catenin Signaling Pathway.
Zhou Z, Liang S, Zhou Z, Liu J, Meng X, Zou F, Yu C, Cai S
Frontiers in pharmacology 2022;13:795934
Frontiers in pharmacology 2022;13:795934
Extracellular HMGB1 Impairs Macrophage-Mediated Efferocytosis by Suppressing the Rab43-Controlled Cell Surface Transport of CD91.
Wang Y, Zhang W, Xu Y, Wu D, Gao Z, Zhou J, Qian H, He B, Wang G
Frontiers in immunology 2022;13:767630
Frontiers in immunology 2022;13:767630
Alpha-Asaronol Alleviates Dysmyelination by Enhancing Glutamate Transport Through the Activation of PPARγ-GLT-1 Signaling in Hypoxia-Ischemia Neonatal Rats.
Ge Y, Zhen F, Liu Z, Feng Z, Wang G, Zhang C, Wang X, Sun Y, Zheng X, Bai Y, Yao R
Frontiers in pharmacology 2022;13:766744
Frontiers in pharmacology 2022;13:766744
Sinomenine Hydrochloride Promotes TSHR-Dependent Redifferentiation in Papillary Thyroid Cancer.
Zhang J, Zhao A, Jia X, Li X, Liang Y, Liu Y, Xie X, Qu X, Wang Q, Zhang Y, Gao R, Yu Y, Yang A
International journal of molecular sciences 2022 Sep 14;23(18)
International journal of molecular sciences 2022 Sep 14;23(18)
History of Previous Midlife Estradiol Treatment Permanently Alters Interactions of Brain Insulin-like Growth Factor-1 Signaling and Hippocampal Estrogen Synthesis to Enhance Cognitive Aging in a Rat Model of Menopause.
Baumgartner NE, McQuillen SM, Perry SF, Miller S, Maroteaux MJ, Gibbs RB, Daniel JM
The Journal of neuroscience : the official journal of the Society for Neuroscience 2022 Oct 19;42(42):7969-7983
The Journal of neuroscience : the official journal of the Society for Neuroscience 2022 Oct 19;42(42):7969-7983
Geniposide inhibits SphK1 membrane targeting to restore macrophage polarization balance in collagen-induced arthritis mice.
Gan PR, Wang RH, Deng R, Wu H, Bu YH, Chen FY, Dong XT, Ke JT
European journal of pharmacology 2022 Oct 15;933:175271
European journal of pharmacology 2022 Oct 15;933:175271
Activation of the Chemokine Receptor CCR1 and Preferential Recruitment of Gαi Suppress RSV Replication: Implications for Developing Novel Respiratory Syncytial Virus Treatment Strategies.
Li J, Xue L, Wang J, Meng A, Qiao J, Li M, Wang X, Meng L, Ning J, Gao X, Li W, Ma C, Wei L
Journal of virology 2022 Nov 23;96(22):e0130922
Journal of virology 2022 Nov 23;96(22):e0130922
Effects of apolipoprotein E on regulating insulin sensitivity via regulating insulin receptor signalosome in caveolae.
Liu M, Chen MY, An L, Ma SQ, Mei J, Huang WH, Zhang W
Life sciences 2022 Nov 1;308:120929
Life sciences 2022 Nov 1;308:120929
Identification of Marek's disease virus pUL56 homologue and analysis of critical amino acid stretches indispensable for its intracellular localization.
Zhang J, Xu B, Ma D, Song J, Liu X, Wei P, Huang T
Virus research 2022 May;313:198741
Virus research 2022 May;313:198741
Comprehensive analysis identified a reduction in ATP1A2 mediated by ARID3A in abdominal aortic aneurysm.
Wang Q, Li N, Guo X, Huo B, Li R, Feng X, Fang Z, Zhu XH, Wang Y, Yi X, Wei X, Jiang DS
Journal of cellular and molecular medicine 2022 May;26(10):2866-2880
Journal of cellular and molecular medicine 2022 May;26(10):2866-2880
Identification and functional analysis of two new de novo KCNMA1 variants associated with Liang-Wang syndrome.
Liang L, Liu H, Bartholdi D, van Haeringen A, Fernandez-Jaén A, Peeters EEA, Xiong H, Bai X, Xu C, Ke T, Wang QK
Acta physiologica (Oxford, England) 2022 May;235(1):e13800
Acta physiologica (Oxford, England) 2022 May;235(1):e13800
Graphene oxide leads to mitochondrial-dependent apoptosis by activating ROS-p53-mPTP pathway in intestinal cells.
Feng W, Wang J, Li B, Liu Y, Xu D, Cheng K, Zhuang J
The international journal of biochemistry & cell biology 2022 May;146:106206
The international journal of biochemistry & cell biology 2022 May;146:106206
Homophilic ATP1A1 binding induces activin A secretion to promote EMT of tumor cells and myofibroblast activation.
Chen YI, Chang CC, Hsu MF, Jeng YM, Tien YW, Chang MC, Chang YT, Hu CM, Lee WH
Nature communications 2022 May 26;13(1):2945
Nature communications 2022 May 26;13(1):2945
Low-dose metformin targets the lysosomal AMPK pathway through PEN2.
Ma T, Tian X, Zhang B, Li M, Wang Y, Yang C, Wu J, Wei X, Qu Q, Yu Y, Long S, Feng JW, Li C, Zhang C, Xie C, Wu Y, Xu Z, Chen J, Yu Y, Huang X, He Y, Yao L, Zhang L, Zhu M, Wang W, Wang ZC, Zhang M, Bao Y, Jia W, Lin SY, Ye Z, Piao HL, Deng X, Zhang CS, Lin SC
Nature 2022 Mar;603(7899):159-165
Nature 2022 Mar;603(7899):159-165
Gamma frequency light flicker regulates amyloid precursor protein trafficking for reducing β-amyloid load in Alzheimer's disease model.
Shen Q, Wu X, Zhang Z, Zhang D, Yang S, Xing D
Aging cell 2022 Mar;21(3):e13573
Aging cell 2022 Mar;21(3):e13573
CX-5461 is a potent immunosuppressant which inhibits T cell-mediated alloimmunity via p53-DUSP5.
Pan G, Zhang J, Han Y, Chen Y, Guo X, Cui X, Cheng M, Gao H, Wang J, Jiang F
Pharmacological research 2022 Mar;177:106120
Pharmacological research 2022 Mar;177:106120
lncRNA HITT inhibits metastasis by attenuating Rab5-mediated endocytosis in lung adenocarcinoma.
Wang X, Zheng S, Yang F, Zhang W, Zhao D, Xue X, Lin Q, He Y, Hu G, Hu Y
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Mar 2;30(3):1071-1088
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Mar 2;30(3):1071-1088
A novel and efficient murine model of Bietti crystalline dystrophy.
Wang Y, Liu Y, Liu S, Li X, Liu X, Jiao M, Yang Y, Luo X, Wang F, Wan X, Sun X
Disease models & mechanisms 2022 Mar 1;15(3)
Disease models & mechanisms 2022 Mar 1;15(3)
Alteration in Rab11-mediated endocytic trafficking of LDL receptor contributes to angiotensin II-induced cholesterol accumulation and injury in podocytes.
Hu J, Zhu Z, Chen Z, Yang Q, Liang W, Ding G
Cell proliferation 2022 Jun;55(6):e13229
Cell proliferation 2022 Jun;55(6):e13229
Identification of different proteins binding to Na, K-ATPase α1 in LPS-induced ARDS cell model by proteomic analysis.
Wen XP, Long G, Zhang YZ, Huang H, Liu TH, Wan QQ
Proteome science 2022 Jun 9;20(1):10
Proteome science 2022 Jun 9;20(1):10
Insulin alleviates LPS-induced ARDS via inhibiting CUL4B-mediated proteasomal degradation and restoring expression level of Na,K-ATPase α1 subunit through elevating HCF-1.
Huang XT, Zheng Y, Long G, Peng WT, Wan QQ
Biochemical and biophysical research communications 2022 Jun 30;611:60-67
Biochemical and biophysical research communications 2022 Jun 30;611:60-67
Changes in the expression of drug-metabolising enzymes and drug transporters in mice with collagen antibody-induced arthritis.
Fujino C, Ueshima S, Katsura T
Xenobiotica; the fate of foreign compounds in biological systems 2022 Jul;52(7):758-766
Xenobiotica; the fate of foreign compounds in biological systems 2022 Jul;52(7):758-766
Multiple Mild Stimulations Reduce Membrane Distribution of CX3CR1 Promoted by Annexin a1 in Microglia to Attenuate Excessive Dendritic Spine Pruning and Cognitive Deficits Caused by a Transient Ischemic Attack in Mice.
Zheng L, Wang Y, Shao B, Zhou H, Li X, Zhang C, Sun N, Shi J
Neuroscience bulletin 2022 Jul;38(7):753-768
Neuroscience bulletin 2022 Jul;38(7):753-768
EXOC4 Promotes Diffuse-Type Gastric Cancer Metastasis via Activating FAK Signal.
Li H, Fu X, Zhao J, Li C, Li L, Xia P, Guo J, Wei W, Zeng R, Wu J, Sun Y, Huang L, Wang X
Molecular cancer research : MCR 2022 Jul 6;20(7):1021-1034
Molecular cancer research : MCR 2022 Jul 6;20(7):1021-1034
CDER167, a dual inhibitor of URAT1 and GLUT9, is a novel and potent uricosuric candidate for the treatment of hyperuricemia.
Zhao ZA, Jiang Y, Chen YY, Wu T, Lan QS, Li YM, Li L, Yang Y, Lin CT, Cao Y, Zhou PZ, Guo JY, Tian YX, Pang JX
Acta pharmacologica Sinica 2022 Jan;43(1):121-132
Acta pharmacologica Sinica 2022 Jan;43(1):121-132
CRISPR/Cas9 delivery by NIR-responsive biomimetic nanoparticles for targeted HBV therapy.
Wang D, Chen L, Li C, Long Q, Yang Q, Huang A, Tang H
Journal of nanobiotechnology 2022 Jan 6;20(1):27
Journal of nanobiotechnology 2022 Jan 6;20(1):27
Cancer cell-expressed BTNL2 facilitates tumour immune escape via engagement with IL-17A-producing γδ T cells.
Du Y, Peng Q, Cheng D, Pan T, Sun W, Wang H, Ma X, He R, Zhang H, Cui Z, Feng X, Liu Z, Zhao T, Hu W, Shen L, Jiang W, Gao N, Martin BN, Zhang CJ, Zhang Z, Wang C
Nature communications 2022 Jan 11;13(1):231
Nature communications 2022 Jan 11;13(1):231
Hyperglycemia induces corneal endothelial dysfunction through attenuating mitophagy.
Chen C, Zhou Q, Li Z, Duan H, Liu Y, Wan L, Wang H, Xie L
Experimental eye research 2022 Feb;215:108903
Experimental eye research 2022 Feb;215:108903
Amino acid starvation-induced LDLR trafficking accelerates lipoprotein endocytosis and LDL clearance.
Chen Y, Wu X, Zhang J, Pan G, Wang X, Guo X, Wang J, Cui X, Gao H, Cheng M, Yang J, Zhang C, Jiang F
EMBO reports 2022 Feb 3;23(3):e53373
EMBO reports 2022 Feb 3;23(3):e53373
Avian Hepatitis E Virus ORF2 Protein Interacts with Rap1b to Induce Cytoskeleton Rearrangement That Facilitates Virus Internalization.
Zhang B, Fan M, Fan J, Luo Y, Wang J, Wang Y, Liu B, Sun Y, Zhao Q, Hiscox JA, Nan Y, Zhou EM
Microbiology spectrum 2022 Feb 23;10(1):e0226521
Microbiology spectrum 2022 Feb 23;10(1):e0226521
Heat Shock Protein Member 8 (HSPA8) Is Involved in Porcine Reproductive and Respiratory Syndrome Virus Attachment and Internalization.
Wang L, Li R, Geng R, Zhang L, Chen XX, Qiao S, Zhang G
Microbiology spectrum 2022 Feb 23;10(1):e0186021
Microbiology spectrum 2022 Feb 23;10(1):e0186021
Blockade of CBX4-mediated β-catenin SUMOylation attenuates airway epithelial barrier dysfunction in asthma.
Liang S, Zhou Z, Zhou Z, Liang J, Lin W, Zhang C, Zhou C, Zhao H, Meng X, Zou F, Yu C, Cai S
International immunopharmacology 2022 Dec;113(Pt A):109333
International immunopharmacology 2022 Dec;113(Pt A):109333
CYLD deubiquitinates plakoglobin to promote Cx43 membrane targeting and gap junction assembly in the heart.
Xie W, Gao S, Yang Y, Li H, Zhou J, Chen M, Yang S, Zhang Y, Zhang L, Meng X, Xie S, Liu M, Li D, Chen Y, Zhou J
Cell reports 2022 Dec 27;41(13):111864
Cell reports 2022 Dec 27;41(13):111864
Extracellular matrix modulating enzyme functionalized biomimetic Au nanoplatform-mediated enhanced tumor penetration and synergistic antitumor therapy for pancreatic cancer.
Yang XY, Zhang JG, Zhou QM, Yu JN, Lu YF, Wang XJ, Zhou JP, Ding XF, Du YZ, Yu RS
Journal of nanobiotechnology 2022 Dec 10;20(1):524
Journal of nanobiotechnology 2022 Dec 10;20(1):524
KIF17 Modulates Epileptic Seizures and Membrane Expression of the NMDA Receptor Subunit NR2B.
Liu Y, Tian X, Ke P, Gu J, Ma Y, Guo Y, Xu X, Chen Y, Yang M, Wang X, Xiao F
Neuroscience bulletin 2022 Aug;38(8):841-856
Neuroscience bulletin 2022 Aug;38(8):841-856
Paeoniflorin-6'O-benzene sulfonate suppresses fibroblast-like synoviocytes proliferation and migration in rheumatoid arthritis through regulating GRK2-Gβγ interaction.
Zhang Y, Yang X, Han C, Wang D, Ma Y, Wei W
Experimental and therapeutic medicine 2022 Aug;24(2):523
Experimental and therapeutic medicine 2022 Aug;24(2):523
C1q/tumour necrosis factor-related protein-3 alleviates high-glucose-induced lipid accumulation and necroinflammation in renal tubular cells by activating the adenosine monophosphate-activated protein kinase pathway.
Du C, Zhu Y, Yang Y, Mu L, Yan X, Wu M, Zhou C, Wu H, Zhang W, Wu Y, Zhang G, Hu Y, Ren Y, Shi Y
The international journal of biochemistry & cell biology 2022 Aug;149:106247
The international journal of biochemistry & cell biology 2022 Aug;149:106247
Functional characterization of human organic anion transporter 10 (OAT10/SLC22A13) as an orotate transporter.
Shinoda Y, Yamashiro T, Hosooka A, Yasujima T, Yuasa H
Drug metabolism and pharmacokinetics 2022 Apr;43:100443
Drug metabolism and pharmacokinetics 2022 Apr;43:100443
Small-Molecule Induction Promotes Corneal Endothelial Cell Differentiation From Human iPS Cells.
Chen J, Ou Q, Wang Z, Liu Y, Hu S, Liu Y, Tian H, Xu J, Gao F, Lu L, Jin C, Xu GT, Cui HP
Frontiers in bioengineering and biotechnology 2021;9:788987
Frontiers in bioengineering and biotechnology 2021;9:788987
Pentadecanoic acid promotes basal and insulin-stimulated glucose uptake in C2C12 myotubes.
Fu WC, Li HY, Li TT, Yang K, Chen JX, Wang SJ, Liu CH, Zhang W
Food & nutrition research 2021;65
Food & nutrition research 2021;65
FXYD6 Regulates Chemosensitivity by Mediating the Expression of Na+/K+-ATPase α1 and Affecting Cell Autophagy and Apoptosis in Colorectal Cancer.
Luo W, Liu Q, Chen X, Liu H, Quan B, Lu J, Zhang K, Wang X
BioMed research international 2021;2021:9986376
BioMed research international 2021;2021:9986376
The cellular prion protein interacts with and promotes the activity of Na,K-ATPases.
Williams D, Mehrabian M, Arshad H, Eid S, Sackmann C, Zhao W, Wang X, Ghodrati F, Verkuyl CE, Watts JC, Schmitt-Ulms G
PloS one 2021;16(11):e0258682
PloS one 2021;16(11):e0258682
GRIN2A Variants Associated With Idiopathic Generalized Epilepsies.
Liu XR, Xu XX, Lin SM, Fan CY, Ye TT, Tang B, Shi YW, Su T, Li BM, Yi YH, Luo JH, Liao WP
Frontiers in molecular neuroscience 2021;14:720984
Frontiers in molecular neuroscience 2021;14:720984
The Extracellular Matrix Enriched With Exosomes for the Treatment on Pulmonary Fibrosis in Mice.
Yu Y, Liu X, Zhao Z, Xu Z, Qiao Y, Zhou Y, Qiao H, Zhong J, Dai J, Suo G
Frontiers in pharmacology 2021;12:747223
Frontiers in pharmacology 2021;12:747223
High-Salt Attenuates the Efficacy of Dapagliflozin in Tubular Protection by Impairing Fatty Acid Metabolism in Diabetic Kidney Disease.
Zou M, Chen Y, Zheng Z, Sheng S, Jia Y, Wang X, Ren S, Yang Y, Li X, Dong W, Guan M, Zhang Q, Xue Y
Frontiers in pharmacology 2021;12:741087
Frontiers in pharmacology 2021;12:741087
Claudin-5 Affects Endothelial Autophagy in Response to Early Hypoxia.
Yu P, Li Y, Zhong G, Li W, Chen B, Zhang J
Frontiers in physiology 2021;12:737474
Frontiers in physiology 2021;12:737474
DEPTOR stabilizes ErbB2 to promote the proliferation and survival of ErbB2-positive breast cancer cells.
Bi Y, Chen X, Wei B, Wang L, Gong L, Li H, Xiong X, Zhao Y
Theranostics 2021;11(13):6355-6369
Theranostics 2021;11(13):6355-6369
Previous estradiol treatment during midlife maintains transcriptional regulation of memory-related proteins by ERα in the hippocampus in a rat model of menopause.
Baumgartner NE, Black KL, McQuillen SM, Daniel JM
Neurobiology of aging 2021 Sep;105:365-373
Neurobiology of aging 2021 Sep;105:365-373
Metformin alleviates inflammation through suppressing FASN-dependent palmitoylation of Akt.
Xiong W, Sun KY, Zhu Y, Zhang X, Zhou YH, Zou X
Cell death & disease 2021 Oct 12;12(10):934
Cell death & disease 2021 Oct 12;12(10):934
Nicotinamide ameliorates energy deficiency and improves retinal function in Cav-1(-/-) mice.
Tang Y, Fang W, Xiao Z, Song M, Zhuang D, Han B, Wu J, Sun X
Journal of neurochemistry 2021 May;157(3):550-560
Journal of neurochemistry 2021 May;157(3):550-560
IL-37b alleviates endothelial cell apoptosis and inflammation in Kawasaki disease through IL-1R8 pathway.
Jia C, Zhuge Y, Zhang S, Ni C, Wang L, Wu R, Niu C, Wen Z, Rong X, Qiu H, Chu M
Cell death & disease 2021 Jun 3;12(6):575
Cell death & disease 2021 Jun 3;12(6):575
MicroRNA-191 blocking the translocation of GLUT4 is involved in arsenite-induced hepatic insulin resistance through inhibiting the IRS1/AKT pathway.
Li W, Wu L, Sun Q, Yang Q, Xue J, Shi M, Tang H, Zhang J, Liu Q
Ecotoxicology and environmental safety 2021 Jun 1;215:112130
Ecotoxicology and environmental safety 2021 Jun 1;215:112130
Down-regulation of A(3)AR signaling by IL-6-induced GRK2 activation contributes to Th17 cell differentiation.
Hu S, Guo P, Wang Z, Zhou Z, Wang R, Zhang M, Tao J, Tai Y, Zhou W, Wei W, Wang Q
Experimental cell research 2021 Feb 15;399(2):112482
Experimental cell research 2021 Feb 15;399(2):112482
Specific protein kinase C isoform exerts chronic inhibition on the slowly activating delayed-rectifier potassium current by affecting channel trafficking.
Gou X, Hu T, Gou Y, Li C, Yi M, Jia M
Channels (Austin, Tex.) 2021 Dec;15(1):262-272
Channels (Austin, Tex.) 2021 Dec;15(1):262-272
A broadly neutralizing humanized ACE2-targeting antibody against SARS-CoV-2 variants.
Du Y, Shi R, Zhang Y, Duan X, Li L, Zhang J, Wang F, Zhang R, Shen H, Wang Y, Wu Z, Peng Q, Pan T, Sun W, Huang W, Feng Y, Feng H, Xiao J, Tan W, Wang Y, Wang C, Yan J
Nature communications 2021 Aug 17;12(1):5000
Nature communications 2021 Aug 17;12(1):5000
Humanin Alleviates Insulin Resistance in Polycystic Ovary Syndrome: A Human and Rat Model-Based Study.
Wang Y, Zeng Z, Zhao S, Tang L, Yan J, Li N, Zou L, Fan X, Xu C, Huang J, Xia W, Zhu C, Rao M
Endocrinology 2021 Aug 1;162(8)
Endocrinology 2021 Aug 1;162(8)
Ultraviolet B irradiation decreases CXCL10 expression in keratinocytes through endoplasmic reticulum stress.
Ohnishi T, Hisadome M, Joji K, Chiba N, Amir MS, Kanekura T, Matsuguchi T
Journal of cellular biochemistry 2021 Apr 28;
Journal of cellular biochemistry 2021 Apr 28;
Olfactomedin-3 Enhances Seizure Activity by Interacting With AMPA Receptors in Epilepsy Models.
Tang S, Wang T, Zhang X, Guo Y, Xu P, Zeng J, Luo Z, Li D, Zheng Y, Luo Y, Yu C, Xu Z
Frontiers in cell and developmental biology 2020;8:722
Frontiers in cell and developmental biology 2020;8:722
Transient Receptor Potential Channel 6 Knockout Ameliorates Kidney Fibrosis by Inhibition of Epithelial-Mesenchymal Transition.
Zhang Y, Yin N, Sun A, Wu Q, Hu W, Hou X, Zeng X, Zhu M, Liao Y
Frontiers in cell and developmental biology 2020;8:602703
Frontiers in cell and developmental biology 2020;8:602703
S-Adenosylmethionine Alleviates Amyloid-β-Induced Neural Injury by Enhancing Trans-Sulfuration Pathway Activity in Astrocytes.
Wan X, Ma B, Wang X, Guo C, Sun J, Cui J, Li L
Journal of Alzheimer's disease : JAD 2020;76(3):981-995
Journal of Alzheimer's disease : JAD 2020;76(3):981-995
Aplysin Retards Pancreatic Necrosis and Inflammatory Responses in NOD Mice by Stabilizing Intestinal Barriers and Regulating Gut Microbial Composition.
Liu Y, Cui X, Gao MQ, Xue M, Xu H, Chang Z, Jiang Y, Liang H
Mediators of inflammation 2020;2020:1280130
Mediators of inflammation 2020;2020:1280130
Comprehensive analysis of the expression of sodium/potassium-ATPase α subunits and prognosis of ovarian serous cystadenocarcinoma.
Huang W, Zhang Y, Xu Y, Yang S, Li B, Huang L, Lou G
Cancer cell international 2020;20:309
Cancer cell international 2020;20:309
A novel mutation of LIM2 causes autosomal dominant membranous cataract in a Chinese family.
Pei R, Liang PF, Ye W, Li J, Ma JY, Zhou J
International journal of ophthalmology 2020;13(10):1512-1520
International journal of ophthalmology 2020;13(10):1512-1520
PD-1-Mediated PI3K/Akt/mTOR, Caspase 9/Caspase 3 and ERK Pathways Are Involved in Regulating the Apoptosis and Proliferation of CD4(+) and CD8(+) T Cells During BVDV Infection in vitro.
Liu Y, Liu S, Wu C, Huang W, Xu B, Lian S, Wang L, Yue S, Chen N, Zhu Z
Frontiers in immunology 2020;11:467
Frontiers in immunology 2020;11:467
Exogenous spermine attenuates rat diabetic cardiomyopathy via suppressing ROS-p53 mediated downregulation of calcium-sensitive receptor.
Wang Y, Chen J, Li S, Zhang X, Guo Z, Hu J, Shao X, Song N, Zhao Y, Li H, Yang G, Xu C, Wei C
Redox biology 2020 May;32:101514
Redox biology 2020 May;32:101514
Anti-human serum albumin autoantibody may be involved in the pathogenesis of autoimmune bullous skin diseases.
Qian H, Cao Y, Sun J, Zu J, Ma L, Zhou H, Tang X, Li Y, Yu H, Zhang M, Bai Y, Xu C, Ishii N, Hashimoto T, Li X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jun;34(6):8574-8595
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jun;34(6):8574-8595
FLIM-FRET-Based Structural Characterization of a Class-A GPCR Dimer in the Cell Membrane.
Yang J, Gong Z, Lu YB, Xu CJ, Wei TF, Yang MS, Zhan TW, Yang YH, Lin L, Liu J, Tang C, Zhang WP
Journal of molecular biology 2020 Jul 24;432(16):4596-4611
Journal of molecular biology 2020 Jul 24;432(16):4596-4611
Loss of mitochondrial protein CHCHD10 in skeletal muscle causes neuromuscular junction impairment.
Xiao Y, Zhang J, Shu X, Bai L, Xu W, Wang A, Chen A, Tu WY, Wang J, Zhang K, Luo B, Shen C
Human molecular genetics 2020 Jul 21;29(11):1784-1796
Human molecular genetics 2020 Jul 21;29(11):1784-1796
NR2B receptor- and calpain-mediated KCC2 cleavage resulted in cognitive deficiency exposure to isoflurane.
Tang X, Zhang X, Li S, Chi X, Luo A, Zhao Y
Neurotoxicology 2020 Jan;76:75-83
Neurotoxicology 2020 Jan;76:75-83
Gamabufotalin induces a negative feedback loop connecting ATP1A3 expression and the AQP4 pathway to promote temozolomide sensitivity in glioblastoma cells by targeting the amino acid Thr794.
Lan YL, Chen C, Wang X, Lou JC, Xing JS, Zou S, Hu JL, Lyu W, Zhang B
Cell proliferation 2020 Jan;53(1):e12732
Cell proliferation 2020 Jan;53(1):e12732
Subcellular trafficking of tubular MDM2 implicates in acute kidney injury to chronic kidney disease transition during multiple low-dose cisplatin exposure.
Su H, Ye C, Lei CT, Tang H, Zeng JY, Yi F, Zhang C
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jan;34(1):1620-1636
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jan;34(1):1620-1636
Alisol A-24-acetate promotes glucose uptake via activation of AMPK in C2C12 myotubes.
Chen JX, Li HY, Li TT, Fu WC, Du X, Liu CH, Zhang W
BMC complementary medicine and therapies 2020 Jan 29;20(1):22
BMC complementary medicine and therapies 2020 Jan 29;20(1):22
Oncogenic role of TYRO3 receptor tyrosine kinase in the progression of pancreatic cancer.
Morimoto M, Horikoshi Y, Nakaso K, Kurashiki T, Kitagawa Y, Hanaki T, Sakamoto T, Honjo S, Umekita Y, Fujiwara Y, Matsura T
Cancer letters 2020 Feb 1;470:149-160
Cancer letters 2020 Feb 1;470:149-160
PLRP2 selectively localizes synaptic membrane proteins via acyl-chain remodeling of phospholipids.
Kuge H, Miyamoto I, Yagyu KI, Honke K
Journal of lipid research 2020 Dec;61(12):1747-1763
Journal of lipid research 2020 Dec;61(12):1747-1763
Palmitoylation of the Bovine Foamy Virus Envelope Glycoprotein Is Required for Viral Replication.
Chai K, Wang Z, Xu Y, Zhang J, Tan J, Qiao W
Viruses 2020 Dec 27;13(1)
Viruses 2020 Dec 27;13(1)
High salt diet elevates the mean arterial pressure of SLC14α1 gene depletion mice.
Wang S, Liu J, Cai H, Liu K, He Y, Liu S, Guo Y, Guo L
Life sciences 2020 Aug 1;254:117751
Life sciences 2020 Aug 1;254:117751
AMPK facilitates intestinal long-chain fatty acid uptake by manipulating CD36 expression and translocation.
Wu W, Wang S, Liu Q, Shan T, Wang X, Feng J, Wang Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Apr;34(4):4852-4869
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Apr;34(4):4852-4869
Knockdown of long noncoding RNA dreh facilitates cell surface GLUT4 expression and glucose uptake through the involvement of vimentin in 3T3-L1 adipocytes.
Takahashi N, Kimura AP, Ohmura K, Naito S, Yoshida M, Ieko M
Gene 2020 Apr 20;735:144404
Gene 2020 Apr 20;735:144404
The Binding of PD-L1 and Akt Facilitates Glioma Cell Invasion Upon Starvation via Akt/Autophagy/F-Actin Signaling.
Chen RQ, Xu XH, Liu F, Li CY, Li YJ, Li XR, Jiang GY, Hu F, Liu D, Pan F, Qiu XY, Chen XQ
Frontiers in oncology 2019;9:1347
Frontiers in oncology 2019;9:1347
Fucoidan prevent murine autoimmune diabetes via suppression TLR4-signaling pathways, regulation DC/Treg induced immune tolerance and improving gut microecology.
Xue M, Liang H, Ji X, Liu Y, Ge Y, Hou L, Sun T
Nutrition & metabolism 2019;16:87
Nutrition & metabolism 2019;16:87
TMEM25 modulates neuronal excitability and NMDA receptor subunit NR2B degradation.
Zhang H, Tian X, Lu X, Xu D, Guo Y, Dong Z, Li Y, Ma Y, Chen C, Yang Y, Yang M, Yang Y, Liu F, Zhou R, He M, Xiao F, Wang X
The Journal of clinical investigation 2019 Sep 3;129(9):3864-3876
The Journal of clinical investigation 2019 Sep 3;129(9):3864-3876
CXCR7 regulates epileptic seizures by controlling the synaptic activity of hippocampal granule cells.
Xu T, Yu X, Deng J, Ou S, Liu X, Wang T, Liu Y, Yang J, Tan C, Yuan J, Chen Y
Cell death & disease 2019 Oct 31;10(11):825
Cell death & disease 2019 Oct 31;10(11):825
Distribution of aquaporins and sodium transporters in the gastrointestinal tract of a desert hare, Lepus yarkandensis.
Zhang J, Li S, Deng F, Baikeli B, Yu W, Liu G
Scientific reports 2019 Nov 12;9(1):16639
Scientific reports 2019 Nov 12;9(1):16639
Laminin α4 overexpression in the anterior lens capsule may contribute to the senescence of human lens epithelial cells in age-related cataract.
Yan Y, Yu H, Sun L, Liu H, Wang C, Wei X, Song F, Li H, Ge H, Qian H, Li X, Tang X, Liu P
Aging 2019 May 10;11(9):2699-2723
Aging 2019 May 10;11(9):2699-2723
CP-25 combined with MTX/ LEF ameliorates the progression of adjuvant-induced arthritis by the inhibition on GRK2 translocation.
Yang X, Zhao Y, Jia X, Wang C, Wu Y, Zhang L, Chang Y, Wei W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Feb;110:834-843
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Feb;110:834-843
Pantoprazole pretreatment elevates sensitivity to vincristine in drug-resistant oral epidermoid carcinoma in vitro and in vivo.
Lu ZN, Shi ZY, Dang YF, Cheng YN, Guan YH, Hao ZJ, Tian B, He HW, Guo XL
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109478
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109478
GRK2 Mediated Abnormal Transduction of PGE2-EP4-cAMP-CREB Signaling Induces the Imbalance of Macrophages Polarization in Collagen-Induced Arthritis Mice.
Yang X, Li S, Zhao Y, Li S, Zhao T, Tai Y, Zhang B, Wang X, Wang C, Chen J, Wang Q, Zhang L, Xu D, Chang Y, Wei W
Cells 2019 Dec 8;8(12)
Cells 2019 Dec 8;8(12)
Rapid affinity purification of intracellular organelles using a twin strep tag.
Xiong J, He J, Xie WP, Hinojosa E, Ambati CSR, Putluri N, Kim HE, Zhu MX, Du G
Journal of cell science 2019 Dec 13;132(24)
Journal of cell science 2019 Dec 13;132(24)
The exocyst complex regulates insulin-stimulated glucose uptake of skeletal muscle cells.
Fujimoto BA, Young M, Carter L, Pang APS, Corley MJ, Fogelgren B, Polgar N
American journal of physiology. Endocrinology and metabolism 2019 Dec 1;317(6):E957-E972
American journal of physiology. Endocrinology and metabolism 2019 Dec 1;317(6):E957-E972
Identification of Protein Kinase C Isoforms Involved in Type 1 Diabetic Encephalopathy in Mice.
Zheng J, Wang Y, Han S, Luo Y, Sun X, Zhu N, Zhao L, Li J
Journal of diabetes research 2018;2018:8431249
Journal of diabetes research 2018;2018:8431249
Proscillaridin A exerts anti-tumor effects through GSK3β activation and alteration of microtubule dynamics in glioblastoma.
Berges R, Denicolai E, Tchoghandjian A, Baeza-Kallee N, Honore S, Figarella-Branger D, Braguer D
Cell death & disease 2018 Sep 24;9(10):984
Cell death & disease 2018 Sep 24;9(10):984
Neuritin promotes neurite and spine growth in rat cerebellar granule cells via L-type calcium channel-mediated calcium influx.
Zhao QR, Lu JM, Li ZY, Mei YA
Journal of neurochemistry 2018 Oct;147(1):40-57
Journal of neurochemistry 2018 Oct;147(1):40-57
Autophagy suppresses self-renewal ability and tumorigenicity of glioma-initiating cells and promotes Notch1 degradation.
Tao Z, Li T, Ma H, Yang Y, Zhang C, Hai L, Liu P, Yuan F, Li J, Yi L, Tong L, Wang Y, Xie Y, Ming H, Yu S, Yang X
Cell death & disease 2018 Oct 18;9(11):1063
Cell death & disease 2018 Oct 18;9(11):1063
Downregulation of Aquaporins (AQP1 and AQP5) and Na,K-ATPase in Porcine Reproductive and Respiratory Syndrome Virus-Infected Pig Lungs.
Zhang J, Yan M, Gu W, Chen A, Liu J, Li L, Zhang S, Liu G
Inflammation 2018 Jun;41(3):1104-1114
Inflammation 2018 Jun;41(3):1104-1114
Succinate induces aberrant mitochondrial fission in cardiomyocytes through GPR91 signaling.
Lu YT, Li LZ, Yang YL, Yin X, Liu Q, Zhang L, Liu K, Liu B, Li J, Qi LW
Cell death & disease 2018 Jun 4;9(6):672
Cell death & disease 2018 Jun 4;9(6):672
DRm217 attenuates myocardial ischemia-reperfusion injury via stabilizing plasma membrane Na(+)-K(+)-ATPase, inhibiting Na(+)-K(+)-ATPase/ROS pathway and activating PI3K/Akt and ERK1/2.
Yan X, Xun M, Wu L, Du X, Zhang F, Zheng J
Toxicology and applied pharmacology 2018 Jun 15;349:62-71
Toxicology and applied pharmacology 2018 Jun 15;349:62-71
Robust diagnosis of Ewing sarcoma by immunohistochemical detection of super-enhancer-driven EWSR1-ETS targets.
Baldauf MC, Orth MF, Dallmayer M, Marchetto A, Gerke JS, Rubio RA, Kiran MM, Musa J, Knott MML, Ohmura S, Li J, Akpolat N, Akatli AN, Özen Ö, Dirksen U, Hartmann W, de Alava E, Baumhoer D, Sannino G, Kirchner T, Grünewald TGP
Oncotarget 2018 Jan 5;9(2):1587-1601
Oncotarget 2018 Jan 5;9(2):1587-1601
Prostaglandin E2 increases migration and proliferation of human glioblastoma cells by activating transient receptor potential melastatin 7 channels.
Tian Y, Yang T, Yu S, Liu C, He M, Hu C
Journal of cellular and molecular medicine 2018 Dec;22(12):6327-6337
Journal of cellular and molecular medicine 2018 Dec;22(12):6327-6337
EMC10 governs male fertility via maintaining sperm ion balance.
Zhou Y, Wu F, Zhang M, Xiong Z, Yin Q, Ru Y, Shi H, Li J, Mao S, Li Y, Cao X, Hu R, Liew CW, Ding Q, Wang X, Zhang Y
Journal of molecular cell biology 2018 Dec 1;10(6):503-514
Journal of molecular cell biology 2018 Dec 1;10(6):503-514
Dexmedetomidine impairs P‑glycoprotein‑mediated efflux function in L02 cells via the adenosine 5'‑monophosphate‑activated protein kinase/nuclear factor‑κB pathway.
He GR, Lin XK, Wang YB, Chen CD
Molecular medicine reports 2018 Apr;17(4):5049-5056
Molecular medicine reports 2018 Apr;17(4):5049-5056
FBW7 increases the chemosensitivity of pancreatic cancer cells to gemcitabine through upregulation of ENT1.
Hu Q, Qin Y, Zhang B, Liang C, Ji S, Shi S, Xu W, Xiang J, Liang D, Ni Q, Yu X, Xu J
Oncology reports 2017 Oct;38(4):2069-2077
Oncology reports 2017 Oct;38(4):2069-2077
Succinate accumulation impairs cardiac pyruvate dehydrogenase activity through GRP91-dependent and independent signaling pathways: Therapeutic effects of ginsenoside Rb1.
Li J, Yang YL, Li LZ, Zhang L, Liu Q, Liu K, Li P, Liu B, Qi LW
Biochimica et biophysica acta. Molecular basis of disease 2017 Nov;1863(11):2835-2847
Biochimica et biophysica acta. Molecular basis of disease 2017 Nov;1863(11):2835-2847
Core 3 mucin-type O-glycan restoration in colorectal cancer cells promotes MUC1/p53/miR-200c-dependent epithelial identity.
Ye J, Wei X, Shang Y, Pan Q, Yang M, Tian Y, He Y, Peng Z, Chen L, Chen W, Wang R
Oncogene 2017 Nov 16;36(46):6391-6407
Oncogene 2017 Nov 16;36(46):6391-6407
PKCζ phosphorylates TRAF2 to protect against intestinal ischemia-reperfusion-induced injury.
Zhou W, Yao J, Wang G, Chen Z, Li Z, Feng D, Li Y, Qasim W, Tan W, Ning S, Tian X
Cell death & disease 2017 Jul 20;8(7):e2935
Cell death & disease 2017 Jul 20;8(7):e2935
Vitamin D supplementation inhibits oxidative stress and upregulate SIRT1/AMPK/GLUT4 cascade in high glucose-treated 3T3L1 adipocytes and in adipose tissue of high fat diet-fed diabetic mice.
Manna P, Achari AE, Jain SK
Archives of biochemistry and biophysics 2017 Feb 1;615:22-34
Archives of biochemistry and biophysics 2017 Feb 1;615:22-34
Inhibition of Calcineurin A by FK506 Suppresses Seizures and Reduces the Expression of GluN2B in Membrane Fraction.
Wen Y, Fu P, Wu K, Si K, Xie Y, Dan W, Zhan Y, Shi Q
Neurochemical research 2017 Aug;42(8):2154-2166
Neurochemical research 2017 Aug;42(8):2154-2166
Regulation of Na(+)-K(+)-ATPase effected high glucose-induced myocardial cell injury through c-Src dependent NADPH oxidase/ROS pathway.
Yan X, Xun M, Dou X, Wu L, Han Y, Zheng J
Experimental cell research 2017 Aug 15;357(2):243-251
Experimental cell research 2017 Aug 15;357(2):243-251
Activation of Na(+)-K(+)-ATPase with DRm217 attenuates oxidative stress-induced myocardial cell injury via closing Na(+)-K(+)-ATPase/Src/Ros amplifier.
Yan X, Xun M, Dou X, Wu L, Zhang F, Zheng J
Apoptosis : an international journal on programmed cell death 2017 Apr;22(4):531-543
Apoptosis : an international journal on programmed cell death 2017 Apr;22(4):531-543
CLIC1 Inhibition Attenuates Vascular Inflammation, Oxidative Stress, and Endothelial Injury.
Xu Y, Zhu J, Hu X, Wang C, Lu D, Gong C, Yang J, Zong L
PloS one 2016;11(11):e0166790
PloS one 2016;11(11):e0166790
Activation of Na+/K+-ATPase attenuates high glucose-induced H9c2 cell apoptosis via suppressing ROS accumulation and MAPKs activities by DRm217.
Yan X, Xun M, Li J, Wu L, Dou X, Zheng J
Acta biochimica et biophysica Sinica 2016 Oct;48(10):883-893
Acta biochimica et biophysica Sinica 2016 Oct;48(10):883-893
Arrhythmogenic cardiomyopathy in a patient with a rare loss-of-function KCNQ1 mutation.
Xiong Q, Cao Q, Zhou Q, Xie J, Shen Y, Wan R, Yu J, Yan S, Marian AJ, Hong K
Journal of the American Heart Association 2015 Jan 23;4(1):e001526
Journal of the American Heart Association 2015 Jan 23;4(1):e001526
20-HETE induces hyperglycemia through the cAMP/PKA-PhK-GP pathway.
Lai G, Wu J, Liu X, Zhao Y
Molecular endocrinology (Baltimore, Md.) 2012 Nov;26(11):1907-16
Molecular endocrinology (Baltimore, Md.) 2012 Nov;26(11):1907-16
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ATP1A1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human ATP1A1. This antibody recognizes human,mouse,rat antigen. The ATP1A1 antibody has been validated for the following applications: ELISA, WB analysis.
