CABT-BL368

antibody from Creative Diagnostics

Targeting: ATP1A1

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

CABT-BL368

Provider

Creative Diagnostics

Product name

Anti-ATP1A1 monoclonal antibody, clone 575.7]

Antibody type

Monoclonal

Description

The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 2 subunit. Mutations in this gene result in familial basilar or hemiplegic migraines, and in a rare syndrome known as alternating hemiplegia of childhood.

Reactivity

Rabbit

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

575.7]

Storage

Store at -20°C. For long term storage store at -80°C. Aliquot to avoid repeated freezing and thawing.