24072-1-AP

antibody from Proteintech Group

Targeting: RAC1 p21-Rac1, Rac-1, TC-25

Provider product page for 24072-1-AP

Western blot

ELISA

Immunocytochemistry

Antibody data

Antibody Data
Antigen structure
References [87]
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Validations
Western blot [1]

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Product number: 24072-1-AP - Provider product page
Provider: Proteintech Group
Product name: Rac1 antibody
Antibody type: Polyclonal
Description: KD/KO validated Rac1 antibody (Cat. #24072-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, WB,ELISA.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

RAC1 protein structure - 24072-1-AP shown in red.

Submitted references The association and clinicopathological significance of Integrin alphavbeta6 and Rac1 expression in gastric carcinoma.

Yu J, Jia W, Liu Q, Yuan A, Jia Z, Sun Y, Li Z, Cao S
Frontiers in oncology 2024;14:1347270

Quantification Quality Control Emerges as a Crucial Factor to Enhance Single-Cell Proteomics Data Analysis.

Yu SH, Chen SC, Wu PS, Kuo PI, Chen TA, Lee HY, Lin MH
Molecular & cellular proteomics : MCP 2024 May;23(5):100768

Spatiotemporal dynamics exhibited by horizontal basal cells reveal a pro-neurogenic pathway during injury-induced olfactory epithelium regeneration.

Louie JD, Barrios-Camacho CM, Bromberg BH, Hintschich CA, Schwob JE
iScience 2024 May 17;27(5):109600

TOM40 mediates the effect of TSPO on postpartum depression partially through regulating calcium homeostasis in microglia.

Zhai DS, Wang XS, Yang L, Jiang YL, Jin YC, Yan YX, Song DK, Zhang K, Han ZK, Liu MY, Wu YM, Ma X, Qi JY, Yang F, Tian F, Li XB, Liu SB
Journal of affective disorders 2024 Mar 1;348:283-296

RAC1(high) NK cell-based immunotherapy in hepatocellular carcinoma via STAT3-NKG2D axis.

Shi X, Chen W, Yin Y, Cao H, Wang X, Jiang W, Li Q, Li X, Yu Y, Wang X
Cancer letters 2024 Jun 28;592:216909

NET1 is a critical regulator of spindle assembly and actin dynamics in mouse oocytes.

Wang S, Wu X, Zhang M, Chang S, Guo Y, Song S, Dai S, Wu K, Zeng S
Reproductive biology and endocrinology : RB&E 2024 Jan 2;22(1):5

Rac1 promotes kidney collecting duct repair by mechanically coupling cell morphology to mitotic entry.

Bock F, Dong X, Li S, Viquez OM, Sha E, Tantengco M, Hennen EM, Plosa E, Ramezani A, Brown KL, Whang YM, Terker AS, Arroyo JP, Harrison DG, Fogo A, Brakebusch CH, Pozzi A, Zent R
Science advances 2024 Feb 9;10(6):eadi7840

Human Parathyroid Hormone (1-34) accelerates skin wound healing through inducing cell migration via up-regulating the expression of Rac1.

Sun Q, Zhou L, Yu Z, Zhang J, Zhang C, Pi H
Cell division 2024 Feb 12;19(1):4

PlexinA1 promotes gastric cancer migration through preventing MICAL1 protein ubiquitin/proteasome-mediated degradation in a Rac1-dependent manner.

Ye F, Xia T, Zhao M, Zhao W, Min P, Wang Y, Wang Q, Zhang Y, Du J
Biochimica et biophysica acta. Molecular basis of disease 2024 Apr;1870(4):167124

Vitamin D Receptor Activation Targets ROS-Mediated Crosstalk Between Autophagy and Apoptosis in Hepatocytes in Cholestasic Mice.

Zheng Z, Xie J, Ma L, Hao Z, Zhang W, Li L
Cellular and molecular gastroenterology and hepatology 2023;15(4):887-901

Comparing synaptic proteomes across five mouse models for autism reveals converging molecular similarities including deficits in oxidative phosphorylation and Rho GTPase signaling.

Carbonell AU, Freire-Cobo C, Deyneko IV, Dobariya S, Erdjument-Bromage H, Clipperton-Allen AE, Page DT, Neubert TA, Jordan BA
Frontiers in aging neuroscience 2023;15:1152562

Dahuang-Taoren, a botanical drug combination, ameliorates adenomyosis via inhibiting Rho GTPases.

Lei Y, Fu X, Chen M, Yi Y, Mao P, Peng L, Qu Z
Frontiers in pharmacology 2023;14:1089004

BACH1 promotes lung adenocarcinoma cell metastasis through transcriptional activation of ITGA2.

Chen Y, Jin L, Ma Y, Liu Y, Zhu Q, Huang Y, Feng W
Cancer science 2023 Sep;114(9):3568-3582

Pleckstrin homology and RhoGEF domain containing G4 (PLEKHG4) leads to the activation of RhoGTPases promoting the malignant phenotypes of thyroid cancer.

Yuan Q, Fan Y, Liu Z, Wang X, Jia M, Dong Y, Geng Z, Zheng J, Lu X
Apoptosis : an international journal on programmed cell death 2023 Oct;28(9-10):1315-1331

Rhein Inhibited Ferroptosis and EMT to Attenuate Diabetic Nephropathy by Regulating the Rac1/NOX1/β-Catenin Axis.

Xiong D, Hu W, Han X, Cai Y
Frontiers in bioscience (Landmark edition) 2023 May 25;28(5):100

Guanine nucleotide exchange factor T exerts the cancer-promoting function in cholangiocarcinoma by enhancing the Wnt-GSK-3β-β-catenin cascade via regulation of Rac1/Cdc42.

Wang X, Zhang X, Sun J, Sun Y, Zhang Y, He L, Wang P, Li F, Sun C
Toxicology and applied pharmacology 2023 May 15;467:116492

Repurposing a tricyclic antidepressant in tumor and metabolism disease treatment through fatty acid uptake inhibition.

Chu Q, An J, Liu P, Song Y, Zhai X, Yang R, Niu J, Yang C, Li B
The Journal of experimental medicine 2023 Mar 6;220(3)

ICP4-Associated Activation of Rap1b Facilitates Herpes Simplex Virus Type I (HSV-1) Infection in Human Corneal Epithelial Cells.

Zhang B, Ding J, Ma Z
Viruses 2023 Jun 27;15(7)

Kinesin Family Member C1 Overexpression Exerts Tumor-Promoting Properties in Head and Neck Squamous Cell Carcinoma via the Rac1/Wnt/β-catenin Pathway.

Yu BY, Shi LG, Jiang C, Wang GK, Liu J, Wu TY
Laboratory investigation; a journal of technical methods and pathology 2023 Jul;103(7):100134

Oral exposure to polystyrene nanoplastics reduced male fertility and even caused male infertility by inducing testicular and sperm toxicities in mice.

Xu W, Yuan Y, Tian Y, Cheng C, Chen Y, Zeng L, Yuan Y, Li D, Zheng L, Luo T
Journal of hazardous materials 2023 Jul 15;454:131470

Human Umbilical Cord Mesenchymal Stem Cells Improve the Status of Hypoxic/Ischemic Cerebral Palsy Rats by Downregulating NogoA/NgR/Rho Pathway.

Luo Y, Qu J, He Z, Zhang M, Zou Z, Li L, Zhang Y, Ye J
Cell transplantation 2023 Jan-Dec;32:9636897231210069

RhoGDIα regulates spermatogenesis through Rac1/cofilin/F-actin signaling.

Zhu H, Wen Z, Zhang A, Liu D, Wang H, Cheng Y, Yang X, Xiao Y, Li J, Sun D, Wu B, Gao J
Communications biology 2023 Feb 23;6(1):214

Cell-in-Cell-Mediated Entosis Reveals a Progressive Mechanism in Pancreatic Cancer.

Song J, Xu R, Zhang H, Xue X, Ruze R, Chen Y, Yin X, Wang C, Zhao Y
Gastroenterology 2023 Dec;165(6):1505-1521.e20

Comprehensive Analysis of MICALL2 Reveals Its Potential Roles in EGFR Stabilization and Ovarian Cancer Cell Invasion.

Xia T, Ye F, Zhao W, Min P, Qi C, Wang Q, Zhao M, Zhang Y, Du J
International journal of molecular sciences 2023 Dec 30;25(1)

LncRNA DGCR5-encoded polypeptide RIP aggravates SONFH by repressing nuclear localization of β-catenin in BMSCs.

Jiang W, Chen Y, Sun M, Huang X, Zhang H, Fu Z, Wang J, Zhang S, Lian C, Tang B, Xiang D, Wang Y, Zhang Y, Jian C, Yang C, Zhang J, Zhang D, Chen T, Zhang J
Cell reports 2023 Aug 29;42(8):112969

Inhibition of Cxcr4 Disrupts Mouse Embryonic Palatal Mesenchymal Cell Migration and Induces Cleft Palate Occurrence.

Zheng X, Zhao X, Wang Y, Chen J, Wang X, Peng X, Ma L, Du J
International journal of molecular sciences 2023 Aug 13;24(16)

Overexpression of PTPRZ1 Regulates p120/β-Catenin Phosphorylation to Promote Carcinogenesis of Oral Submucous Fibrosis.

Ma L, Shen T, Peng H, Wu J, Wang W, Gao X
Journal of oncology 2022;2022:2352360

Spheroid Formation Enhances the Regenerative Capacity of Nucleus Pulposus Cells via Regulating N-CDH and ITGβ1 Interaction.

Wang Y, Wang H, Zhuo Y, Hu Y, Li X, Xu Y, Sun B, Liu M, Zou L, Liu L, Luo L, Zhao C, Li P, Zhou Q
International journal of biological sciences 2022;18(9):3676-3696

Network Pharmacology and Experimental Verification to Explore the Potential Mechanism of Yin-Huo-Tang for Lung Adenocarcinoma Recurrence.

Liu D, Lin S, Li Y, Zhou T, Hu K, Li Q
Drug design, development and therapy 2022;16:375-395

Potential Resistance to Antineoplastic Aminated Fullerenes Mediated by M2-Like Monocyte-Derived Exosomes.

Huo J, Zhou W, Liu Y, Yang S, Li J, Wang C
Frontiers in oncology 2022;12:779939

Differential dysregulation of granule subsets in WASH-deficient neutrophil leukocytes resulting in inflammation.

Johnson JL, Meneses-Salas E, Ramadass M, Monfregola J, Rahman F, Carvalho Gontijo R, Kiosses WB, Pestonjamasp K, Allen D, Zhang J, Osborne DG, Zhu YP, Wineinger N, Askari K, Chen D, Yu J, Henderson SC, Hedrick CC, Ursini MV, Grinstein S, Billadeau DD, Catz SD
Nature communications 2022 Sep 21;13(1):5529

Laminin-511 Activates the Human Induced Pluripotent Stem Cell Survival via α6β1 Integrin-Fyn-RhoA-ROCK Signaling.

Nakashima Y, Tsukahara M
Stem cells and development 2022 Nov;31(21-22):706-719

DOCK2 regulates antifungal immunity by regulating RAC GTPase activity.

Ma X, Tan X, Yu B, Sun W, Wang H, Hu H, Du Y, He R, Gao R, Peng Q, Cui Z, Pan T, Feng X, Wang J, Xu C, Zhu B, Liu W, Wang C
Cellular & molecular immunology 2022 May;19(5):602-618

Graphene oxide leads to mitochondrial-dependent apoptosis by activating ROS-p53-mPTP pathway in intestinal cells.

Feng W, Wang J, Li B, Liu Y, Xu D, Cheng K, Zhuang J
The international journal of biochemistry & cell biology 2022 May;146:106206

CHIR99021 balance TGFβ1 induced human corneal endothelial-to-mesenchymal transition to favor corneal endothelial cell proliferation.

Wang Y, Jin C, Tian H, Xu J, Chen J, Hu S, Li Q, Lu L, Ou Q, Xu GT, Cui H
Experimental eye research 2022 Jun;219:108939

Damnacanthal isolated from morinda species inhibited ovarian cancer cell proliferation and migration through activating autophagy.

Li R, Li H, Lan J, Yang D, Lin X, Xu H, Han B, Yang M, Su B, Liu F, Jiang W
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jun;100:154084

Non-canonical Wnt/calcium signaling is protective against podocyte injury and glomerulosclerosis.

Zhou D, Wang Y, Gui Y, Fu H, Zhou S, Wang Y, Bastacky SI, Stolz DB, Liu Y
Kidney international 2022 Jul;102(1):96-107

The E3 ubiquitin ligase MG53 inhibits hepatocellular carcinoma by targeting RAC1 signaling.

Ma X, Ma X, Zhu L, Zhao Y, Chen M, Li T, Lin Y, Ma D, Sun C, Han L
Oncogenesis 2022 Jul 20;11(1):40

Spiropachysine A suppresses hepatocellular carcinoma proliferation by inducing methuosis in vitro and in vivo.

Fang Y, Zhong T, Yang L, Luo F, Li Q, Wang D, Li Q, Fan Y, Yang X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jul 20;102:154151

Activation of the NLRP3 inflammasome by RAC1 mediates a new mechanism in diabetic nephropathy.

Ying C, Zhou Z, Dai J, Wang M, Xiang J, Sun D, Zhou X
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2022 Feb;71(2):191-204

Klotho functionalization on vascular graft for improved patency and endothelialization.

Zhao P, Fang Q, Gao D, Wang Q, Cheng Y, Ao Q, Wang X, Tian X, Zhang Y, Tong H, Yan N, Hu X, Fan J
Biomaterials advances 2022 Feb;133:112630

Avian Hepatitis E Virus ORF2 Protein Interacts with Rap1b to Induce Cytoskeleton Rearrangement That Facilitates Virus Internalization.

Zhang B, Fan M, Fan J, Luo Y, Wang J, Wang Y, Liu B, Sun Y, Zhao Q, Hiscox JA, Nan Y, Zhou EM
Microbiology spectrum 2022 Feb 23;10(1):e0226521

Metabolic enzyme LDHA activates Rac1 GTPase as a noncanonical mechanism to promote cancer.

Liu J, Zhang C, Zhang T, Chang CY, Wang J, Bazile L, Zhang L, Haffty BG, Hu W, Feng Z
Nature metabolism 2022 Dec;4(12):1830-1846

High MICAL1 expression correlates with cancer progression and immune infiltration in renal clear cell carcinoma.

Yang Y, Ye F, Xia T, Wang Q, Du J
BMC cancer 2022 Dec 27;22(1):1355

Cell-in-cell structure mediates in-cell killing suppressed by CD44.

Su Y, Huang H, Luo T, Zheng Y, Fan J, Ren H, Tang M, Niu Z, Wang C, Wang Y, Zhang Z, Liang J, Ruan B, Gao L, Chen Z, Melino G, Wang X, Sun Q
Cell discovery 2022 Apr 19;8(1):35

CUX1 Facilitates the Development of Oncogenic Properties Via Activating Wnt/β-Catenin Signaling Pathway in Glioma.

Feng F, Zhao Z, Zhou Y, Cheng Y, Wu X, Heng X
Frontiers in molecular biosciences 2021;8:705008

RhoGDI1-Cdc42 Signaling Is Required for PDGF-BB-Induced Phenotypic Transformation of Vascular Smooth Muscle Cells and Neointima Formation.

Qi Y, Liang X, Guan H, Sun J, Yao W
Biomedicines 2021 Sep 6;9(9)

Regulation of local GTP availability controls RAC1 activity and cell invasion.

Bianchi-Smiraglia A, Wolff DW, Marston DJ, Deng Z, Han Z, Moparthy S, Wombacher RM, Mussell AL, Shen S, Chen J, Yun DH, O'Brien Cox A, Furdui CM, Hurley E, Feltri ML, Qu J, Hollis T, Kengne JBN, Fongang B, Sousa RJ, Kandel ME, Kandel ES, Hahn KM, Nikiforov MA
Nature communications 2021 Oct 19;12(1):6091

Overexpression of DTL enhances cell motility and promotes tumor metastasis in cervical adenocarcinoma by inducing RAC1-JNK-FOXO1 axis.

Liu S, Gu L, Wu N, Song J, Yan J, Yang S, Feng Y, Wang Z, Wang L, Zhang Y, Jin Y
Cell death & disease 2021 Oct 11;12(10):929

33-kDa ANXA3 isoform contributes to hepatocarcinogenesis via modulating ERK, PI3K/Akt-HIF and intrinsic apoptosis pathways.

Guo C, Li N, Dong C, Wang L, Li Z, Liu Q, Ma Q, Greenaway FT, Tian Y, Hao L, Liu S, Sun MZ
Journal of advanced research 2021 May;30:85-102

Salvianolic acid A prevented cerebrovascular endothelial injury caused by acute ischemic stroke through inhibiting the Src signaling pathway.

Liu CD, Liu NN, Zhang S, Ma GD, Yang HG, Kong LL, Du GH
Acta pharmacologica Sinica 2021 Mar;42(3):370-381

Three-dimensional cell-culture platform based on hydrogel with tunable microenvironmental properties to improve insulin-secreting function of MIN6 cells.

Zhang M, Yan S, Xu X, Yu T, Guo Z, Ma M, Zhang Y, Gu Z, Feng Y, Du C, Wan M, Hu K, Han X, Gu N
Biomaterials 2021 Mar;270:120687

Loss of QKI in macrophage aggravates inflammatory bowel disease through amplified ROS signaling and microbiota disproportion.

Wang W, Zhai D, Bai Y, Xue K, Deng L, Ma L, Du T, Ye Z, Qu D, Xiang A, Chen G, Zhao Y, Wang L, Lu Z
Cell death discovery 2021 Mar 23;7(1):58

Tumour-derived exosomal lncRNA-SOX2OT promotes bone metastasis of non-small cell lung cancer by targeting the miRNA-194-5p/RAC1 signalling axis in osteoclasts.

Ni J, Zhang X, Li J, Zheng Z, Zhang J, Zhao W, Liu L
Cell death & disease 2021 Jul 2;12(7):662

Long noncoding RNA EPB41L4A-AS1 functions as an oncogene by regulating the Rho/ROCK pathway in colorectal cancer.

Bin J, Nie S, Tang Z, Kang A, Fu Z, Hu Y, Liao Q, Xiong W, Zhou Y, Tang Y, Jiang J
Journal of cellular physiology 2021 Jan;236(1):523-535

LIM domain-containing 2 (LIMD2) promotes the progress of ovarian cancer via the focal adhesion signaling pathway.

Chen L, Qian J, You Q, Ma J
Bioengineered 2021 Dec;12(2):10089-10100

6-Thioguanine Inhibits Herpes Simplex Virus 1 Infection of Eyes.

Chen D, Liu Y, Zhang F, You Q, Ma W, Wu J, Wu Z
Microbiology spectrum 2021 Dec 22;9(3):e0064621

Cucurbitacin I induces apoptosis in ovarian cancer cells through oxidative stress and the p190B‑Rac1 signaling axis.

Li R, Xiao J, Tang S, Lin X, Xu H, Han B, Yang M, Liu F
Molecular medicine reports 2020 Sep;22(3):2545-2550

RhoG/Rac1 signaling pathway involved in migration and invasion of salivary adenoid cystic carcinoma cells.

Xu ZD, Hao T, Gan YH
Oral diseases 2020 Mar;26(2):302-312

Modulation of the Pol II CTD Phosphorylation Code by Rac1 and Cdc42 Small GTPases in Cultured Human Cancer Cells and Its Implication for Developing a Synthetic-Lethal Cancer Therapy.

Zhang B, Zhong X, Sauane M, Zhao Y, Zheng ZL
Cells 2020 Mar 4;9(3)

Oxidation of Reduced Graphene Oxide via Cellular Redox Signaling Modulates Actin-Mediated Neurotransmission.

Kang Y, Liu J, Yin S, Jiang Y, Feng X, Wu J, Zhang Y, Chen A, Zhang Y, Shao L
ACS nano 2020 Mar 24;14(3):3059-3074

RhoA/ROCK Pathway Activation is Regulated by AT1 Receptor and Participates in Smooth Muscle Migration and Dedifferentiation via Promoting Actin Cytoskeleton Polymerization.

Qi Y, Liang X, Dai F, Guan H, Sun J, Yao W
International journal of molecular sciences 2020 Jul 29;21(15)

Plastin 1 drives metastasis of colorectal cancer through the IQGAP1/Rac1/ERK pathway.

Zhang T, Wang Z, Liu Y, Huo Y, Liu H, Xu C, Mao R, Zhu Y, Liu L, Wei D, Liu G, Pan B, Tang Y, Zhou Z, Yang C, Guo Y
Cancer science 2020 Aug;111(8):2861-2871

TNFAIP8 promotes AML chemoresistance by activating ERK signaling pathway through interaction with Rac1.

Pang Y, Zhao Y, Wang Y, Wang X, Wang R, Liu N, Li P, Ji M, Ye J, Sun T, Li J, Ma D, Lu F, Ji C
Journal of experimental & clinical cancer research : CR 2020 Aug 14;39(1):158

Effects of mevalonate kinase interference on cell differentiation, apoptosis, prenylation and geranylgeranylation of human keratinocytes are attenuated by farnesyl pyrophosphate or geranylgeranyl pyrophosphate.

Li M, Min W, Wang J, Wang L, Li Y, Zhou N, Yang Z, Qian Q
Experimental and therapeutic medicine 2020 Apr;19(4):2861-2870

YAP promotes multi-drug resistance and inhibits autophagy-related cell death in hepatocellular carcinoma via the RAC1-ROS-mTOR pathway.

Zhou Y, Wang Y, Zhou W, Chen T, Wu Q, Chutturghoon VK, Lin B, Geng L, Yang Z, Zhou L, Zheng S
Cancer cell international 2019;19:179

Proteomics Analysis Identifies IRSp53 and Fascin as Critical for PRV Egress and Direct Cell-Cell Transmission.

Yu FL, Miao H, Xia J, Jia F, Wang H, Xu F, Guo L
Proteomics 2019 Dec;19(23):e1900009

CSTF2-Induced Shortening of the RAC1 3'UTR Promotes the Pathogenesis of Urothelial Carcinoma of the Bladder.

Chen X, Zhang JX, Luo JH, Wu S, Yuan GJ, Ma NF, Feng Y, Cai MY, Chen RX, Lu J, Jiang LJ, Chen JW, Jin XH, Liu HL, Chen W, Guan XY, Kang TB, Zhou FJ, Xie D
Cancer research 2018 Oct 15;78(20):5848-5862

Annexin A5 regulates hepatocarcinoma malignancy via CRKI/II-DOCK180-RAC1 integrin and MEK-ERK pathways.

Sun X, Liu S, Wang J, Wei B, Guo C, Chen C, Sun MZ
Cell death & disease 2018 May 25;9(6):637

PEDF improves cardiac function in rats subjected to myocardial ischemia/reperfusion injury by inhibiting ROS generation via PEDF‑R.

Zhao Q, Liu Z, Huang B, Yuan Y, Liu X, Zhang H, Qiu F, Zhang Y, Li Y, Miao H, Dong H, Zhang Z
International journal of molecular medicine 2018 Jun;41(6):3243-3252

Silencing Ras-Related C3 Botulinum Toxin Substrate 1 Inhibits Growth and Migration of Hypopharyngeal Squamous Cell Carcinoma via the P38 Mitogen-Activated Protein Kinase Signaling Pathway.

Cheng H, Wang W, Wang G, Wang A, Du L, Lou W
Medical science monitor : international medical journal of experimental and clinical research 2018 Feb 7;24:768-781

Combination antitumor immunotherapy with VEGF and PIGF siRNA via systemic delivery of multi-functionalized nanoparticles to tumor-associated macrophages and breast cancer cells.

Song Y, Tang C, Yin C
Biomaterials 2018 Dec;185:117-132

Graphene Oxide Induced Perturbation to Plasma Membrane and Cytoskeletal Meshwork Sensitize Cancer Cells to Chemotherapeutic Agents.

Zhu J, Xu M, Gao M, Zhang Z, Xu Y, Xia T, Liu S
ACS nano 2017 Mar 28;11(3):2637-2651

Nicotine facilitates VSMC dysfunction through a miR-200b/RhoGDIA/cytoskeleton module.

Liang D, Wang Z, Yan Z, Hou S, Xu W, Wang L, Shang M, Qiao Z
Scientific reports 2017 Mar 2;7:43798

Cathelicidin-WA Improves Intestinal Epithelial Barrier Function and Enhances Host Defense against Enterohemorrhagic Escherichia coli O157:H7 Infection.

Yi H, Hu W, Chen S, Lu Z, Wang Y
Journal of immunology (Baltimore, Md. : 1950) 2017 Feb 15;198(4):1696-1705

A taspine derivative supresses Caco-2 cell growth by competitively targeting EphrinB2 and regulating its pathway.

Dai B, Wang W, Ma Y, Liu R, Zhang Y
Oncology reports 2016 Sep;36(3):1526-34

Dihydroartemisinin suppresses pancreatic cancer cells via a microRNA-mRNA regulatory network.

Li Y, Wang Y, Kong R, Xue D, Pan S, Chen H, Sun B
Oncotarget 2016 Sep 20;7(38):62460-62473

Metastasis suppressor 1 regulates neurite outgrowth in primary neuron cultures.

Yu J, Lin S, Wang M, Liang L, Zou Z, Zhou X, Wang M, Chen P, Wang Y
Neuroscience 2016 Oct 1;333:123-31

Upregulated TRIO expression correlates with a malignant phenotype in human hepatocellular carcinoma.

Wang B, Fang J, Qu L, Cao Z, Zhou J, Deng B
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2015 Sep;36(9):6901-8

NADPH oxidase-derived production of reactive oxygen species is involved in learning and memory impairments in 16-month-old female rats.

Kan H, Hu W, Wang Y, Wu W, Yin Y, Liang Y, Wang C, Huang D, Li W
Molecular medicine reports 2015 Sep;12(3):4546-4553

Sanguinarine inhibits Rac1b-rendered cell survival enhancement by promoting apoptosis and blocking proliferation.

Ying L, Li G, Wei SS, Wang H, An P, Wang X, Guo K, Luo XJ, Gao JM, Zhou Q, Li W, Yu Y, Li YG, Duan JL, Wang YP
Acta pharmacologica Sinica 2015 Feb;36(2):229-40

Screening key microRNAs for castration-resistant prostate cancer based on miRNA/mRNA functional synergistic network.

Zhu J, Wang S, Zhang W, Qiu J, Shan Y, Yang D, Shen B
Oncotarget 2015 Dec 22;6(41):43819-30

Baculovirus induces host cell aggregation via a Rho/Rok-dependent mechanism.

Deng Z, Huang Z, Yuan M, Yang K, Pang Y
The Journal of general virology 2014 Oct;95(Pt 10):2310-2320

Protective effects of ginsenoside Rg1 on chronic restraint stress induced learning and memory impairments in male mice.

Wang Y, Kan H, Yin Y, Wu W, Hu W, Wang M, Li W, Li W
Pharmacology, biochemistry, and behavior 2014 May;120:73-81

Elevated Orai1 expression mediates tumor-promoting intracellular Ca2+ oscillations in human esophageal squamous cell carcinoma.

Zhu H, Zhang H, Jin F, Fang M, Huang M, Yang CS, Chen T, Fu L, Pan Z
Oncotarget 2014 Jun 15;5(11):3455-71

RACK1 promotes the proliferation, migration and invasion capacity of mouse hepatocellular carcinoma cell line in vitro probably by PI3K/Rac1 signaling pathway.

Wu J, Meng J, Du Y, Huang Y, Jin Y, Zhang J, Wang B, Zhang Y, Sun M, Tang J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2013 May;67(4):313-9

The phosphodiesterase-5 inhibitor vardenafil reduces oxidative stress while reversing pulmonary arterial hypertension.

Fan YF, Zhang R, Jiang X, Wen L, Wu DC, Liu D, Yuan P, Wang YL, Jing ZC
Cardiovascular research 2013 Aug 1;99(3):395-403

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: The Rac1 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human Rac1. This antibody recognizes human antigen. The Rac1 antibody has been validated for the following applications: ELISA, WB analysis.
Appendix: 24072-1-AP.pdf

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