abx117114

antibody from Abbexa

Targeting: THRB ERBA-BETA, ERBA2, GRTH, NR1A2, PRTH, THR1, THRB1, THRB2

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

abx117114

Provider

Abbexa

Product name

Thyroid Hormone Receptor Beta (THRB) Antibody

Antibody type

Polyclonal

Description

THRB Antibody is a Rabbit Polyclonal antibody against THRB. The protein encoded by this gene is a nuclear hormone receptor for triiodothyronineIt is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormoneKnockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormoneMutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH)Several alternatively spliced transcript variants encoding the same protein have been observed for this gene.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µg

Storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.