Antibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 55139-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#55139-1-AP, RRID:AB_10794449
- Product name
- ARHGAP10 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ARHGAP10 antibody (Cat. #55139-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references SMAD4 inhibits glycolysis in ovarian cancer through PI3K/AKT/HK2 signaling pathway by activating ARHGAP10.
The Rac-GEF Tiam1 controls integrin-dependent neutrophil responses.
Enhanced BCAT1 activity and BCAA metabolism promotes RhoC activity in cancer progression.
Identification and Validation of an Apoptosis-Related Gene Prognostic Signature for Oral Squamous Cell Carcinoma.
Rho GTPase-activating protein 10 (ARHGAP10/GRAF2) is a novel autoantibody target in patients with autoimmune encephalitis.
The Beta-Tubulin Isotype TUBB6 Controls Microtubule and Actin Dynamics in Osteoclasts.
miR‑337‑3p inhibits gastric tumor metastasis by targeting ARHGAP10.
Downregulated expression of ARHGAP10 correlates with advanced stage and high Ki-67 index in breast cancer.
ARHGAP10 Inhibits the Proliferation and Metastasis of CRC Cells via Blocking the Activity of RhoA/AKT Signaling Pathway.
miR-3174 Contributes to Apoptosis and Autophagic Cell Death Defects in Gastric Cancer Cells by Targeting ARHGAP10.
The Cdc42 guanine nucleotide exchange factor FGD6 coordinates cell polarity and endosomal membrane recycling in osteoclasts.
Wu K, Gong W, Sun H, Li W, Chen L, Duan Y, Zhu J, Zhang H, Ke H
Cancer reports (Hoboken, N.J.) 2024 Jan 17;7(2):e1976
Cancer reports (Hoboken, N.J.) 2024 Jan 17;7(2):e1976
The Rac-GEF Tiam1 controls integrin-dependent neutrophil responses.
Hornigold K, Baker MJ, Machin PA, Chetwynd SA, Johnsson AK, Pantarelli C, Islam P, Stammers M, Crossland L, Oxley D, Okkenhaug H, Walker S, Walker R, Segonds-Pichon A, Fukui Y, Malliri A, Welch HCE
Frontiers in immunology 2023;14:1223653
Frontiers in immunology 2023;14:1223653
Enhanced BCAT1 activity and BCAA metabolism promotes RhoC activity in cancer progression.
Qian L, Li N, Lu XC, Xu M, Liu Y, Li K, Zhang Y, Hu K, Qi YT, Yao J, Wu YL, Wen W, Huang S, Chen ZJ, Yin M, Lei QY
Nature metabolism 2023 Jul;5(7):1159-1173
Nature metabolism 2023 Jul;5(7):1159-1173
Identification and Validation of an Apoptosis-Related Gene Prognostic Signature for Oral Squamous Cell Carcinoma.
Wang S, Zhang S, Lin Z, Ma J, Zhu L, Liao G
Frontiers in oncology 2022;12:889049
Frontiers in oncology 2022;12:889049
Rho GTPase-activating protein 10 (ARHGAP10/GRAF2) is a novel autoantibody target in patients with autoimmune encephalitis.
Jarius S, Komorowski L, Regula JU, Haas J, Brakopp S, Wildemann B
Journal of neurology 2022 Oct;269(10):5420-5430
Journal of neurology 2022 Oct;269(10):5420-5430
The Beta-Tubulin Isotype TUBB6 Controls Microtubule and Actin Dynamics in Osteoclasts.
Maurin J, Morel A, Guérit D, Cau J, Urbach S, Blangy A, Bompard G
Frontiers in cell and developmental biology 2021;9:778887
Frontiers in cell and developmental biology 2021;9:778887
miR‑337‑3p inhibits gastric tumor metastasis by targeting ARHGAP10.
Wang Z, Yao L, Li Y, Hao B, Wang M, Wang J, Gu W, Zhan H, Liu G, Wu Q
Molecular medicine reports 2020 Feb;21(2):705-719
Molecular medicine reports 2020 Feb;21(2):705-719
Downregulated expression of ARHGAP10 correlates with advanced stage and high Ki-67 index in breast cancer.
Li Y, Zeng B, Li Y, Zhang C, Ren G
PeerJ 2019;7:e7431
PeerJ 2019;7:e7431
ARHGAP10 Inhibits the Proliferation and Metastasis of CRC Cells via Blocking the Activity of RhoA/AKT Signaling Pathway.
Liu L, Xie D, Xie H, Huang W, Zhang J, Jin W, Jiang W, Xie D
OncoTargets and therapy 2019;12:11507-11516
OncoTargets and therapy 2019;12:11507-11516
miR-3174 Contributes to Apoptosis and Autophagic Cell Death Defects in Gastric Cancer Cells by Targeting ARHGAP10.
Li B, Wang L, Li Z, Wang W, Zhi X, Huang X, Zhang Q, Chen Z, Zhang X, He Z, Xu J, Zhang L, Xu H, Zhang D, Xu Z
Molecular therapy. Nucleic acids 2017 Dec 15;9:294-311
Molecular therapy. Nucleic acids 2017 Dec 15;9:294-311
The Cdc42 guanine nucleotide exchange factor FGD6 coordinates cell polarity and endosomal membrane recycling in osteoclasts.
Steenblock C, Heckel T, Czupalla C, Espírito Santo AI, Niehage C, Sztacho M, Hoflack B
The Journal of biological chemistry 2014 Jun 27;289(26):18347-59
The Journal of biological chemistry 2014 Jun 27;289(26):18347-59
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human heart tissue were subjected to SDS PAGE followed by western blot with 55139-1-AP(ARHGAP10 antibody) at dilution of 1:800
- Sample type
- tissue
Supportive validation
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ARHGAP10 antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human ARHGAP10. This antibody recognizes human, mouse antigen. The ARHGAP10 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human skeletal muscle using 55139-1-AP(ARHGAP10 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue