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- Product number
- 18985-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#18985-1-AP, RRID:AB_2782960
- Product name
- iNOS antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated iNOS antibody (Cat. #18985-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references A Needlelike Nano-hydroxyapatite-Based Hydrogel Accelerates Critical Bone Defect Regeneration via Osteo-/Angiogenesis and Osteoimmune Regulation.
Photocrosslinkable Chitosan Quaternary Ammonium Salt-Based Ternary Hydrogel with Fibroblast Growth Factor 21 for Diabetic Wound Healing.
Lnc-CHRM4-2:1 Inhibits M2 Polarization and Efferocytosis of Macrophages by Downregulating MerTK and SLC2A1 in Rheumatoid Arthritis.
Targeting Pulmonary Hypertension: Elucidating Sophocarpine's Protective Role via Preclinical Models.
The mechanism of Vicenin-2 in ameliorating skin photoaging: involvement of m6A-modified macrophage polarization.
Gomphus floccosus (Schw.) Sing. extract attenuates alcoholic liver disease by suppressing macrophage glycolysis and M1 polarization.
ROS-Responsive Double-Layer Microneedles Enable Sequential Antibacterial and Immunomodulatory Therapy for Infected Wound Healing.
CCL5 promotes angiotensin II-induced cardiac remodeling through regulation of platelet-driven M2 macrophage polarization.
ZEB1 maintains mitochondrial fission and macrophage efferocytosis by restraining MFN2, thereby limiting inflammation and improving tendon‑bone healing.
Asperuloside-Mediated Activation of Nrf2 Inhibits the NF-κB Pathway and Suppresses Osteoarthritis Progression.
Combination of Hypoxia-Preconditioned ADSCs and Deferoxamine Can Speed Up the Healing of Diabetic Wounds by Promoting Angiogenesis and Regulating Macrophage Polarization.
Edible Bird's Nest Attenuates Neuroinflammation and Cognitive Impairment in a Model of Chronic Fatigue Syndrome.
Ultrasound Activated Piezoelectric Dural Patches to Drive Endogenous Neural Stem Cell-Mediated Repair Traumatic Brain Injury.
Taohong Siwu decoction and its components regulate the M1/M2 polarization of macrophages to alleviate inflammatory injury in sepsis via the RAGE.
Persistent histone H3K27 acetylation contributes to excessive scar formation after spinal cord injury through the regulation of microglial cholesterol accumulation.
Cascade Therapy of Periodontitis via Sequential Release of Ribosome-Targeting Antimicrobial Peptide and Irisin From a Multifunctional MOF-Based System.
Early Radial Extracorporeal Shockwave Stimulation on Proximal Tibial Circular Osteotomy Site Enhanced Heterotopic Skin Wound Healing via Small Extracellular Vesicles.
Targeting Microglial CD49a Inhibits Neuroinflammation and Demonstrates Therapeutic Potential for Parkinson's Disease.
Royal jelly protein hydrolysates accelerate in vitro diabetic wound healing by enhancing keratinocytes functions and suppressing macrophage-mediated inflammation.
Vericiguat Attenuates Post-Myocardial Infarction Inflammation Associated With Macrophage Polarization and Regulation of the Survivin/Caspase-6 Pathway.
IL-3 Modulates Microglia Polarization and Attenuates Neuroinflammation in Traumatic Brain Injury.
Cordycepin alleviates ischaemic brain injury by suppressing microglia-induced neuroinflammation via regulating the Notch1 signalling pathway.
Human umbilical cord mesenchymal stem cells alleviate hypoxic-ischemia-induced white-matter injury in neonatal rats by regulating polarization of microglia.
Exercise reverses high-fat diet-induced perivascular adipose tissue dysfunction through modulation of UCP2 and TXNIP/NLRP3 pathways.
α-Ketoglutarate protects against cartilage damage via epigenetically driven metabolic reprogramming in osteoarthritis models.
Tanshinone IIA-pretreated mesenchymal stem cells alleviate neuroinflammation in 3×Tg-AD mice via the TREM2/PI3K/Akt pathway.
ROS-Responsive Prodrug Containing Dihydroartemisinin and Cinnamaldehyde for the Potential Treatment of Nonalcoholic Steatohepatitis.
The engineered probiotic strain Lactococcus lactis MG1363-pMG36e-GLP-1 regulates microglial polarization and gut dysbiosis in a transgenic mouse model of Parkinson's disease.
Exosomal lncRNA OTUD6B-AS1 as a pathogenic nanocarrier promotes inflammatory macrophage polarization in endometritis via a targetable ceRNA circuit.
AICAR improves depression-like behaviors and is associated with hippocampal AMPK activation and modulation of neurogenesis and neuroinflammation in a microbiota disruption model.
Integrated whole transcriptome sequencing, network pharmacology and in vivo validation reveal that Compound Wufengcao Liquid promotes pressure injury healing via PPARγ-mediated macrophage polarization.
Qingjin Pingchuan formula attenuates pulmonary inflammation by reprogramming neutrophil SHP1-JAK2/SRC-STAT3 signaling.
Cannabidiol synergizes with methotrexate to attenuate rheumatoid arthritis via STAT3/NF-κB signalling-mediated M1 macrophage polarization.
A potent icaritin derivative ameliorates Parkinson's disease via GPER-mediated mitophagy restoration and dopaminergic neuroprotection.
Momordin Ic alleviates inflammation and skin barrier dysfunction of atopic dermatitis in vitro and in vivo.
Cu(2+)-chelated epigallocatechin gallate nanoparticle-functionalized hydrogel promotes osteogenesis by inhibiting ferroptosis.
Celastrol ameliorates depressive-like behaviors in a rat model of post-stroke depression and is associated with reduced neuroinflammation and restoration of serotonergic- and synaptic-related proteins.
A composite sustained-release system with immunomodulatory and synergistic osteogenic differentiation effects for repairing inflammatory alveolar bone defects.
Dragon's blood and its active components ameliorate pressure overload-induced heart failure via remodeling of cardiac lymphatics.
Sodium Houttuyfonate improves cognitive impairment in mice after chronic sleep deprivation by inhibiting microglial inflammation and ferroptosis.
Targeting of CIRP attenuates osteoarthritis progression via suppressing TLR4/NF‑κB/NLRP3 signaling axis.
Ecdysteroid-enriched fraction of Cyathula officinalis suppresses synovial proliferation and inflammation to ameliorate RA by inhibiting the AKT/PI3K/mTOR signaling pathway.
Down-regulation of lipocalin-2 alleviates depressive-like behaviors in mice through modulation of microglial activation.
SS-31 improves post-cardiac arrest brain injury by inhibiting microglial ferroptosis and polarization.
Oligosaccharide esters from Polygala paniculata with their NO inhibitory activity.
Adipose-derived stem cells (ADSCs)-derived DKK1 promotes cutaneous wound healing by inducing M2 macrophage polarization via PI3K/AKT and JNK activation.
Limosilactobacillus reuteri DSM17938 Attenuates Neuroinflammatory Responses After Spinal Cord Injury by Modulating Tryptophan Metabolism.
T1WI-SWI Dual Modal Magnetic Resonance Nanoprobes for Accurate Diagnosis of Early Stage Alzheimer's Disease.
Neuropeptide SP protects against colitis and linked anxiety-like behavior through the putative roles of gut microbiota and metabolite inositol.
Asiatic Acid Attenuates Salmonella typhimurium-Induced Neuroinflammation and Neuronal Damage by Inhibiting the TLR2/Notch and NF-κB Pathway in Microglia.
Propyl Gallate Attenuates Cognitive Deficits Induced by Chronic Sleep Deprivation Through Nrf2 Activation and NF-κB Inhibition.
Mechanism of ultrasound-guided renal parenchymal injection of MSCs for the treatment of chronic kidney disease: down-regulated SGK1 promotes M2 macrophage polarization.
Anti-tumor effect of flavonoids isolated from Bidens Pilosa L. by regulating the activity of myeloid-derived suppressor cells within the tumor microenvironment in mice.
Single-cell transcriptomics uncover RNF130-mediated TNF-α pathway activation and worenine synergy with paclitaxel in breast cancer.
Rewiring brain structural and functional disconnection with acupuncture in rat model of vascular cognitive impairment and dementia.
Hydrogel with cell-cell adhesion cues enhances neural regeneration.
Propyl Gallate Mitigates Gastric Injury Caused by Indomethacin in Wistar Rats.
The mechanism of indigo naturalis and its active ingredients against ulcerative colitis.
Bioactive nanoparticles from clam extracts mitigate alcoholic liver injury by modulating multiple pathways.
Taurine-loaded covalent organic frameworks for alleviating post-radiation bone regeneration disorder.
Inulin with different degrees of polymerization adopts different strategies to mitigate radiation-induced intestinal injury: focus on intestinal epithelial or T cell homeostasis.
Effect and Mechanism of Apoptotic Bodies from Inflammatory Periodontal Ligament Stem Cells on Macrophage M1 Polarisation.
Inhibition of Setd7 protects against cardiomyocyte hypertrophy via inhibiting lipid oxidation.
Integrating TWAS, chemical-genomic networks, and experimental models: melatonin as a ferroptosis inhibitor in osteoarthritis therapy.
Neuroprotective Effects of Salvia Miltiorrhiza-Derived Extracellular Nanovesicles in Traumatic Brain Injury.
Pressure-sensitive composite bandages with high toughness, self-healability and strong tissues adhesion for rapid bone fixation and accelerated osteogenesis via immunomodulation and neovascularization.
4D-printed Fe3O4-PLLA scaffolds modulate osteoimmune microenvironment for oral bone repair.
Piezo1 mediated scaffold-free rapid generation of self-mineralized bone organoids via activating Wnt signaling.
Apigenin alleviates DFZ-induced cardiac, renal, and intestinal injury in carp by modulating oxidative stress and inflammatory responses.
Microfluidics-Inspired Microgels with Intrinsic Bioactivity for Advanced Burn Wound Therapy.
Inhalation of mesenchymal stromal cell-derived extracellular vesicles activates macrophage polarization through the miR-22-3p/NLRP3/IL-1β pathway, ameliorating lung ischemia - reperfusion injury.
hsa_circ_0006168 drives microglial activation in TNC via miR-99b-5p/KDM6B axis to promote central sensitization in migraine.
Mangosteen (Garcinia mangostana) Pericarp and Leaf Tinctures Inhibit LPS-Induced Pro-Inflammatory Responses in Macrophages and Activate Nrf2.
Saussurea involucrata oral liquid alleviates joint inflammation in CIA rats by modulating macrophage polarization and glucose metabolism.
AE-MXene-modified titanium alloy promotes osseointegration by regulating the AMPK-MTOR-autophagy pathway in macrophage.
Kynurenic Acid/GPR35 Signaling Protects the Infarcted Heart by Suppressing Macrophage mtDNA-Triggered cGAS-STING Activation.
Integration of Bulk and Single-Cell Transcriptomics Reveals Prognostic and Immunological Roles of MTHFD2 in Clear Cell Renal Cell Carcinoma.
Phosphoglycerate dehydrogenase-mediated serine reprogramming aggravates macrophage hyperinflammation in murine Pseudomonas aeruginosa pneumonia.
Ultraviolet-induced Glycyrrhiza polysaccharide hydrogels with different mechanical strength for wound management.
Houttuynia cordata Polysaccharide Alleviates Hepatic Ischemia-Reperfusion Injury by Regulating Macrophage Polarization via Inhibiting the TLR4/NF-κB Signaling Pathway.
An immunomodulatory hydrogel featuring antibacterial and ROS-scavenging functions for enhanced burn wound healing.
A dual-action nanoparticle approach for spinal cord injury treatment: ferroptosis inhibition, inflammation control, and Myelin preservation.
Blood-brain barrier disruption and neuroinflammation in the hippocampus of a cardiac arrest porcine model: Single-cell RNA sequencing analysis.
lncRNA MALAT1-mediated regulation of cholesterol-oxidative stress-iron metabolic dysregulation by paeoniflorin in osteoarthritic chondrocytes.
Mechanisms of topical Mahoniae Caulis against acute mastitis: Integrating SMR, network pharmacology, molecular docking, and experimental validation.
Titanium ion inhibits osteogenic ability of osteoblasts by up-regulating osteoblast Agt gene via macrophages.
Bacteria-responsive DNAgel system for targeted delivery of photothermally enhanced MXene/MoS(2) in the treatment of pyogenic osteomyelitis.
Microglial-Derived Cholesterol 25-Hydroxylase Promotes Epileptic Seizure and Neuroinflammation Mediated by NLRP3 Inflammasome and Lipid Metabolism.
A Dual-Action Nucleoside-Based Supramolecular Hydrogel Combats Periodontitis by Disrupting the Bacteria-Osteoclast Cascade.
MicroRNA-493-5p engineered exosomes delivered via piezoelectric microneedles for epigenetic modulation of macrophages in diabetic wound healing.
Natural polysaccharide-nucleic acid nanocomplex alleviates myocardial infarction by driving chronologically programmed macrophage polarization.
Sequential delivery of sinigrin and dabigatran by an in situ self-stabilizing dynamic hydrogel attenuates intervertebral disc degeneration.
Dual-responsive PDA-HP hydrogel enables mitochondria-targeted mild photothermal therapy for spinal cord repair.
Lycium barbarum polysaccharides and/or Bifidobacterium longum exert anti-inflammation and modulate gut microbiota in rats with dextran sulfate sodium-induced ulcerative colitis.
Macrophage Migratory Inhibitory Factor May Contribute to the Production of Nitric Oxide in Obstructive Sleep Apnea.
Laminarin attenuates neuroinflammation in MPTP-induced Parkinson's disease mouse model via inhibiting dectin-1/Syk/NF-κB signaling.
Framework nucleic acid-based hydrogel for sequential immune regulation and endogenous TGF-β1 capture in wound healing.
White light-triggered cascade NO/ROS-releasing platform with synergistic antibacterial and angiogenic effects for infected wound healing.
Zinc-Containing Bioactive Glass Programs Macrophage Polarization through Extracellular Traps Regulation for Enhanced Diabetic Wound Healing.
Interfacial Bioengineering of Dynamic Networks Hybrid Hydrogel for Programmed Intervention in Oral Precancerous Epithelial States.
Histochemical characterization of muscularis macrophage loss and disruption of a miR-93-5p-AHNAK neuro-immune axis in Hirschsprung's disease.
Discovery of Imidazo[2,1-b][1,3,4]thiadiazole-Based MNK Inhibitors with Anti-inflammatory Efficacy via Dual Suppression of eIF4E Phosphorylation and NF-κB Signaling.
Triptolide alleviates pathological neovascularisation in oxygen-induced retinopathy via inhibiting the inflammation mediated by NF-κB pathway.
Aerobic Exercise Alleviates Oxidative Stress and Inflammation to Attenuate High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease in ApoE(-/-) Mice.
Crosstalk Between Clec7a and TLR4 Immune Pathway Drives Renal Damage in a Cisplatin-Induced Acute Kidney Injury Model.
Xuming tongmai decoction modulates astrocyte polarization and mitophagy via the PINK1/Parkin pathway in a rat model of acute ischemic stroke.
Kv1.3 regulates macrophage immune function through PI3K/AKT signaling pathway to alleviate metabolic dysfunction-associated steatohepatitis.
Ligustilide Suppresses Macrophage-Mediated Intestinal Inflammation and Restores Gut Barrier via EGR1-ADAM17-TNF-α Pathway in Colitis Mice.
A Biodegradable Zinc Alloy Membrane with Regulation of Macrophage Polarization for Early Vascularized Bone Regeneration.
Ginsenoside Rh2-Pretreated Mesenchymal Stem Cell Exosomes Ameliorate Collagen-Induced Arthritis via N6-Methyladenosine Methylation.
The Extracellular Matrix Promotes Diabetic Oral Wound Healing by Modulating the Microenvironment.
HIF-1-mediated macrophage metabolic reprogramming promotes AKI to CKD transition.
TNFAIP3 alleviates cerebral ischemia-reperfusion injury by inhibiting M1 microglia polarization via deubiquitination of RACK1.
Delivery of miR-26a-5p by Subcutaneous Adipose Tissue-Derived Extracellular Vesicles Alleviates Acute Lung Injury in Mice Through CHUK/NF-κB Pathway.
Lung Tissue Extracellular Vesicles-Mediated Delivery of miR-128-3p as a Novel Mechanism of Acute Lung Inflammation.
Lactate Facilitates Pancreatic Repair Following Acute Pancreatitis by Promoting Reparative Macrophage Polarization.
Tenascin-C Facilitates Microglial Polarization via TLR4/MyD88/NF-κB Pathway Following Subarachnoid Hemorrhage.
ITGB7 Remodels Inflammation and Immune Microenvironment and Enhances Checkpoint Inhibitor-Based Immunotherapy in Pancreatic Cancer.
Semaphorin 6D Alleviates Osteoarthritis by Inhibiting NLRP3 Inflammasome Activation and Endoplasmic Reticulum Stress.
DNase I alleviates renal inflammatory injury in MRL/lpr mice by inhibiting NETs formation.
Low-dose extracorporeal shock wave attenuates sepsis-related acute lung injury by targeting mitochondrial dysfunction and pyroptosis crosstalk in type II alveolar epithelial cells.
miR-223 alleviates DSS-induced colitis by prompting macrophage M2 polarization through PPAR-γ/FOXO1 signaling.
Resistance training alleviates muscle atrophy and muscle dysfunction by reducing inflammation and regulating compromised autophagy in aged skeletal muscle.
Ginsenoside Re ameliorates thioacetamide-induced acute liver injury through inhibiting autophagy-NLRP3 inflammasome pathway.
Acetylcholine from tuft cells promotes M2 macrophages polarization in Hirschsprung-associated enterocolitis.
Hydrogen sulfide as a therapeutic agent for diabetic wounds: effects on inflammation and fibroblast pyroptosis.
A multifunctional injectable microsphere with enhanced near-infrared photo-antibacterial, ROS scavenging, and anti-inflammatory properties for periodontitis treatment.
Hsa_circ_0058495-mediated IGF2BP2 ubiquitination and m6A modification of MEKK1 promote the progression of PDAC.
Bioinspired exosome-SiO(2) nanohybrid therapeutic for rheumatoid arthritis treatment.
The Effects of M2 Macrophages-Derived Exosomes on Urethral Fibrosis and Stricture in Scar Formation.
A multifunctional dihydromyricetin-loaded hydrogel for the sequential modulation of diabetic wound healing and glycemic control.
The effect of ponicidin on CFA-induced chronic inflammatory pain and its mechanism based on network pharmacology and molecular docking.
Leukemia Inhibitory Factor via JAK-STAT Signaling Drives Beryllium Sulfate-Induced Epithelial-Mesenchymal Transition in 16HBE Cells.
Chronic Pod-Mod E-Cigarette Aerosol Exposure Induces Aortic Dysfunction in Hypercholesterolemic Mice: Role of Oxidative Stress and Inflammation.
Extraction, separation, structure identification and anti-inflammatory activity of polysaccharides from Lamiophlomis Rotata.
TBX21 knockdown attenuates neuroinflammation induced by intracerebral hemorrhage via the SIRT1-WDR5-H3K4me3 axis.
Flavonoids from the stems of Ammopiptanthus nanus and their in vitro and in vivo anti-inflammatory activities.
Piezoelectric-IL-4 programmed regulation of immuno-microenvironment-induced mesenchymal stem cell recruitment and differentiation for bone regeneration.
Modulating Macrophage-Nucleus Pulposus Cell Crosstalk via Sequential Drug Delivery Attenuates Disc Degeneration.
A Myelin Debris Cleaner for Spinal Cord Injury Recovery: Polycaprolactone / Cell Membrane Assembled Scaffolds.
Inhibition of Dectin-1 alleviates inflammation in early diabetic retinopathy by regulating microglia phenotype.
METTL14 knockdown augmented the polarization of M2-like macrophages to promote acute myeloid leukemia progression.
Isoacteoside alleviates LPS-induced depressive-like behaviors in mice by inhibiting neuroinflammation through regulating microglial polarization and oxidative stress.
Proinflammatory polarization of adipose tissue macrophages in cows with subclinical ketosis constitutes a critical driver of adipose tissue remodeling and inflammation.
Piceatannol improves autoimmune hepatitis by inhibiting the immune activities of T cells and macrophages through binding with c-Jun.
Effect of Oral Peritumoral Tissue on Infiltration and Differentiation of Tumor-Associated Macrophages in Oral Squamous Cell Carcinoma.
Artesunate suppresses ocular inflammation in endotoxin-induced uveitis through inhibiting the NF-κB signaling pathway and M1 macrophage polarization.
Curcumin inhibits aortic dissection progression: Insights from the integrated analysis of network pharmacology, gut microbiota, and serum metabolomics.
Polyphyllin I enhances the anti-tumor efficacy of Palbociclib by reversing M2 macrophage polarization in lung cancer.
Melatonin Prevents the Progression of MASLD via Inhibiting FFAs-Induced Ferroptosis through KEAP1/NRF2/HO-1 Pathway.
Therapeutic targeting of Nrf2/HO-1/NF-κB signaling axis with casticin mitigates intervertebral disc degeneration: in vitro and in vivo investigations.
On-Demand ER Stress Modulation in Tumor Cells and TAMs via an Adaptively Transformable Nanoplatform Enhances Photodynamic Immunotherapy.
Synergistic exacerbation of periprosthetic osteolysis by inflammatory bowel disease and titanium ions: Impaired osteogenesis of BMSCs via PI3K/AKT signaling.
Self-assembled extracellular matrix-lipid nanoparticle composite for site-specific siRNA delivery to improve cardiac repair post-myocardial infarction.
Chiral gold nanoparticles manipulate osteoimmune microenvironment via macrophage autophagy for bone regeneration.
Magnoflorine ameliorates cartilage degradation in osteoarthritis through inhibition of mitochondrial reactive oxygen species-mediated activation of the NLRP3 inflammasome.
TSP50 in Neural Stem Cells Regulates Aging-Related Cognitive Decline and Neuroinflammation by Altering the Gut Microbiota.
Oligodendrocyte-specific knockout of FPN1 affects CNS myelination defects and depression-like behavior in mice.
Injectable Immune-Regulating Mesenchymal Stem Cells Hydrogel for Localized Scleroderma Treatment.
Implantable drug delivery systems with a bioinspired zwitterionic nanocoating resist foreign body reaction-induced obstruction and enable sustained delivery.
Cardiotoxic Effect Induced by F-53B via Nitric Oxide Signalling on Parkin(-/-) Mice.
Intratumoral microbiota-driven macrophage reprogramming in pancreatic cancer via Blautia metabolite 6-hydroxyhexanoic acid.
Dental pulp stem cells promote the recovery of spinal cord injury by regulating microglia polarization via JAK2/STAT3 signaling pathway.
Arginyl-fructosyl-glucose (AFG), a major Maillard reaction product of red ginseng, improved kidney and pancreatic injury in vitro and in vivo in type 2 diabetes mellitus.
MBD2 deficiency attenuates CCl(4)-induced hepatic fibrosis by inhibiting M2 macrophage polarization.
Microwave therapy promotes wound healing in diabetic mice by activating IL-33/ST2-mediated M2 macrophage polarization.
Protective Effect of Mesaconate on Autoimmune Hepatitis via Suppression of Inflammatory Response and Oxidative Stress.
Galangin Alleviates Intervertebral Disc Degeneration via the Nrf2/NF-κB Pathway.
CXCL10 modulates airway inflammation in asthma via Sirt3-dependent macrophage homeostasis.
Research on the Protective Effects and Mechanisms of Gallic Acid Against Cognitive Impairment Induced by Chronic Sleep Deprivation.
Dysregulated Protein s-Nitrosylation Promotes Nitrosative Stress and Disease Progression in Heart Failure With Preserved Ejection Fraction.
Nitric oxide regulates spindle dynamics to modulate the maturation of goat oocytes.
Knockdown of USP22 alleviates LPS-induced microglial inflammation and mouse depressive-like behaviors via KAT2A.
NPB-1575 attenuates neuroinflammation and resists ferroptosis in rat ischemic stroke via IRS2 signaling pathway.
Innovative DNA tetrahedron inspired by ancient mortise-and-tenon technique offers new immunotherapy strategy for metastatic breast cancer.
Interleukin-10 Modified Human Mesenchymal Stromal Cells Markedly Alleviated Periodontitis by Inducing Macrophage M2 Polarisation.
MSC-derived small extracellular vesicles attenuate diabetic retinopathy through miR-29a-3p regulated microglia M1-like polarization.
Exosomal CagA induces macrophage polarization and ferroptosis by JAK1-2/STAT1 signaling pathway in Helicobacter pylori-associated gastritis.
Treadmill exercise alleviates STING-mediated microglia pyroptosis and polarization via activating mitophagy post-TBI.
AMPK upregulates SOCS1 to promote TFEB nuclear transfer, enhances autophagy, inhibits macrophage M1 polarization and relieves acute lung injury.
RRBP1 Inhibition Reduces Microglial M1 Polarization and Inflammation-Mediated Neuronal Loss and Oxidative Stress by Regulating ERK Pathway in Alzheimer's Disease.
Hepatic acetyl-CoA metabolism modulates neuroinflammation and depression susceptibility via acetate.
Quercetin as a Novel Antidepressant: Mechanistic Insights into Its Neuroprotective and Anti-inflammatory Effects.
The miR-125a-5p/IRF4 Axis Mediates Sodium Arsenite-Induced M2 Macrophage Polarization.
Salidroside-Pretreated Small Extracellular Vesicles Derived from Human Umbilical Cord Mesenchymal Stem Cells Promote Blood-Spinal Cord Barrier Repair After Spinal Cord Injury in Mice.
Omentin-1 reduced synovial M1 macrophages through SIRT6 signaling pathway and alleviated knee osteoarthritis response in mice.
TIM3 attenuates morphine antinociceptive tolerance and microglial neuroinflammation by suppressing the TRAF6/NF-κB pathway in male mice.
Treatment of Parkinson's Disease with an Anti-Inflammasome NLRP3 Inhibitor Derived from a Natural Product.
Single-atom Ca nanozyme induces glioma death through Ca(2+)-overload-enhanced catalytic tumor nanotherapy, ferroptosis and synergistic remodeling of the immune microenvironment.
Wuling San ameliorates cerebral ischemia-reperfusion injury via suppression of the TRPM2/NLRP3 pathway.
Application of Dental Pulp Stem Cell-Derived Intracellular Vesicles for Diabetic Wound Healing.
Paraquat induced neuro-immunotoxicity: Dysregulated microglial antigen processing and mitochondrial activated mechanisms.
Ultrasound-triggered injectable piezoelectric nanocomposite hyaluronic acid-based hydrogel for modulating inflammation and chondrogenesis in osteoarthritis treatment.
Remote ischemic conditioning as a potential therapy for Parkinson's Disease: Inhibiting TLR4-Driven neuroinflammation and oxidative damage.
Icariin modulates the tumor microenvironment in colorectal cancer by targeting M2 macrophage polarization via PI3K/AKT pathway.
Th22 cells promote the transition from homeostatic to reactive microglia in diabetic encephalopathy.
Platelet activation stimulates macrophages to enhance ulcerative colitis through PF4/CXCR3 signaling.
Early Potentially Irreversible Cardiac Damage in Fabry Disease Precedes Gb3 Inclusion Body Formation.
Nose-to-Brain Delivery of Circular RNA SCMH1-Loaded Lipid Nanoparticles for Ischemic Stroke Therapy.
Regulation of Nrf2/GPX4 Signaling Pathway by Hyperbaric Oxygen Protects Against Depressive Behavior and Cognitive Impairment in a Spinal Cord Injury Rat Model.
Flammulina velutipes polysaccharide exerts immunomodulatory function involving RSAD2 to regulate the NF-κB/MAPK signaling pathway in RAW264.7 macrophage cells and in mouse spleen cells.
Temporal and spatial expression of Phosphodiesterase-4B after sciatic nerve compression in rats and its mechanism of action on sciatic nerve repair.
Biodegradable Piezoelectric Janus Membrane with Enhanced Antibacterial and Osteoinductive Properties for Periodontitis Therapy.
Dectin-1 participates in neuroinflammation and dopaminergic neurodegeneration through synergistic signaling crosstalk with TLR4.
MiR-29a-3p ameliorate behavioral deficiency in hypoxia-ischemia brain damage in neonatal mice by inhibiting BTG2.
Comparative efficacy of preventive vs. therapeutic resveratrol in modulating gut microbiota and alleviating inflammation in DSS-induced colitis.
Therapeutic potential of ADSC-derived exosomes in acute lung injury by regulating macrophage polarization through IRF7/NLRP3 signaling.
Polygonum multiflorum Inhibits Pulmonary Inflammation and Fibrosis in PM(2.5)-Induced Dysfunction Through the Regulation of the TLR4/TGF-β1 Signaling Pathway in Mice.
Comparison of the Immunomodulatory Roles of Porcine Milk-Derived Extracellular Vesicles from Different Stages of Lactation.
Inhibiting cathepsin B alleviates acute lung injury caused by sepsis through suppression of pyroptosis in lung epithelial cells.
Single-cell sequencing reveals alterations in the ovarian immune microenvironment regulated by 17β-estradiol in neonatal mice.
Astragaloside IV prevents liver fibrosis by blocking glycolysis-mediated macrophage M1 polarization.
Neuroprotective, Antioxidant and Anti-Inflammatory Effect of Greek Pomegranate Seed Oil on N2a Neuroblastoma Cells and Mild Cognitive Impairment Patients.
IGF2BP3-mediated m(6)A modification of RASGRF1 promoting joint injury in rheumatoid arthritis.
Allocryptopine Attenuates Inflammatory Responses in Microglial Cells Via TLR4-Dependent NF-κB and p38 MAPK Pathways.
Trimethylamine N-oxide aggravates human aortic valve interstitial cell inflammation by regulating the macrophages polarization through a N6-methyladenosine-mediated pathway.
Multifunctional sericin-based biomineralized nanoplatforms with immunomodulatory and angio/osteo-genic activity for accelerated bone regeneration in periodontitis.
Synergistic therapeutic effect of parecoxib and ilomastat combination in osteoarthritis via inhibition of IL-17/PI3K/AKT/NF-κB activity.
Colon-Targeted Ginseng Polysaccharides-Based Microspheres for Improving Ulcerative Colitis via Anti-Inflammation and Gut Microbiota Modulation.
Genetically Programmed Single-Component Protein Hydrogel for Spinal Cord Injury Repair.
M1 polarization of hepatic macrophages in cows with subclinical ketosis is an important cause of liver injury.
Erianin alleviates autoimmune myocarditis by suppressing the M1 polarization of macrophages via the NF-κB/NLRP3 signaling pathway.
Indole-3-Propionic Acid Attenuates Neuroinflammation and Cognitive Deficits by Inhibiting the RAGE-JAK2-STAT3 Signaling Pathway.
Sinomenine alleviates neuroinflammation in chronic cerebral hypoperfusion by promoting M2 microglial polarization and inhibiting neuronal pyroptosis via exosomal miRNA-223-3p.
Novel regulation mechanism of histone methyltransferase SMYD5 in rheumatoid arthritis.
Tremella polysaccharide microneedles loaded with magnetic dental pulp stem cell intracellular vesicles used for androgenic alopecia.
Berberine Exerts Neuroprotective Effects in Alzheimer's Disease by Switching Microglia M1/M2 Polarization Through PI3K-AKT Signaling.
Anti-TNFα and Anti-IL-1β Monoclonal Antibodies Preserve BV-2 Microglial Homeostasis Under Hypoxia by Mitigating Inflammatory Reactivity and ATF4/MAPK-Mediated Apoptosis.
Supplementing Freezing Medium with Crocin Exerts a Protective Effect on Bovine Spermatozoa Through the Modulation of a Heat Shock-Mediated Apoptotic Pathway.
Activated NETosis of bone marrow neutrophils up-regulates macrophage osteoclastogenesis via cGAS-STING/AKT2 pathway to promote osteoporosis.
Integrative multi-omics reveals the mechanism of ulcerative colitis treated with Ma-Mu-Ran antidiarrheal capsules.
LXRα agonists ameliorates acute rejection after liver transplantation via ABCA1/MAPK and PI3K/AKT/mTOR signaling axis in macrophages.
Integration of single-cell RNA sequencing and network pharmacology to elucidate the effect of Yantiao Formula on alleviating ALI by regulating the polarization of alveolar macrophages.
Injectable hydrogels with ROS-triggered drug release enable the co-delivery of antibacterial agent and anti-inflammatory nanoparticle for periodontitis treatment.
Microneedles Loaded with Nitric-Oxide Driven Nanomotors Improve Force-Induced Efferocytosis Impairment and Sterile Inflammation by Revitalizing Macrophage Energy Metabolism.
Orally-administrable supramolecular probiotic capsules enable cooperative colon-targeted inflammation inhibition for ameliorating ulcerative colitis.
GSK3β Substrate-competitive Inhibitors Regulate the gut Homeostasis and Barrier Function to Inhibit Neuroinflammation in Scopolamine-induced Alzheimer's Disease Model Mice.
L-arginine modified mesoporous bioactive glass with ROS scavenging and NO release for periodontitis treatment.
Mesenchymal Stem Cells Attenuate Podocyte Injury in Diabetic Nephropathy Through the Promotion of Type 2 Macrophage Polarization.
Multifunctional injectable hydrogel incorporating EGCG-Cu complexes for synergistic antibacterial, immunomodulatory, and osteogenic therapy in periodontitis.
Curcumin-encapsulated exosomes in bisphosphonate-modified hydrogel microspheres promote bone repair through macrophage polarization and DNA damage mitigation.
Enhanced inhibition of neuronal ferroptosis and regulation of microglial polarization with multifunctional traditional Chinese medicine active ingredients-based selenium nanoparticles for treating spinal cord injury.
Ultrasound-responsive taurine lipid nanoparticles attenuate oxidative stress and promote macrophage polarization for diabetic wound healing.
Liposome of Phlorizin promote the repair of carotid atherosclerosis in rats by regulating inflammation and the Nrf2 signaling pathway.
Scutellaria baicalensis Extracts Restrict Intestinal Epithelial Cell Ferroptosis by Regulating Lipid Peroxidation and GPX4/ACSL4 in Colitis.
Biochanin A mitigates colitis by inhibiting ferroptosis-mediated intestinal barrier dysfunction, oxidative stress, and inflammation via the JAK2/STAT3 signaling pathway.
Abnormal iron metabolism in the zona incerta in Parkinson's disease mice.
Therapeutic Delivery of circDYM by Perillyl Alcohol Nanoemulsion Alleviates LPS-Induced Depressive-Like Behaviors.
Luteolin ameliorates kainic acid-induced seizure by modulating GADD45B and reducing oxidative stress in hippocampal neurons.
Dehydrodiisoeugenol targets NOD2 exerting dual effects against colitis and colorectal cancer: a double-edged sword.
IL-37 inhibited inflammation to improve gestational diabetes mellitus through the GSK3/NF-κB pathway.
Malvidin Alleviates Lipopolysaccharide-Induced Acute Lung Injury by Modulating JAK2/STAT3 Signaling to Inhibit Macrophage M1 Polarization and Oxidative Stress.
Cerium-Organic Framework and Resveratrol Composite Hydrogel Scaffold with Dual Antioxidant Activity for Enhanced Bone Regeneration.
Pretreatment with Citrus reticulata 'Chachi' Polysaccharide Alleviates Alcohol-Induced Gastric Ulcer by Inhibiting NLRP3/ASC/Caspase-1 and Nrf2/HO-1 Signaling Pathways.
Xanthoxylin Regulating the Inflammatory Microenvironment After Spinal Cord Injury Through Inhibition of the NF-κB Signaling Pathway.
A Slow Hydrogen Sulfide Donor GYY-4137 Partially Improves Vascular Function in Spontaneously Hypertensive Rats Fed a High-Fat Diet.
Novel insights into beta cell ER stress CHOP and its role in HFpEF development.
Celastrol improves endothelial function in diet-induced obesity mice via attenuating endoplasmic reticulum stress through the activation of AMPK pathway.
A Dual-Factor Scaffold for Spinal Cord Injury Repair Targeting Inflammation and Ferroptosis.
Platelet Membrane-Coated Drug-Loaded Nanoparticles for Dual-Modal Imaging and Photodynamic Therapy in Triple-Negative Breast Cancer.
Oxidized fucoidan-based nanocomposite hydrogel for cryptotanshinone delivery and prevention of postoperative abdominal adhesions.
Fate reversal: Exosome-driven macrophage rejuvenation and bacterial-responsive drug release for infection immunotherapy in diabetes.
Secretome enriched with small extracellular vesicles derived from human gingiva-derived mesenchymal stem cells enhances rat tongue muscle regeneration.
Tinosinenside A inhibits neuroinflammation and protects HT22 cells by suppressing the TLR4/NF-κB/NLRP3 signaling pathway in BV2 cells.
Quercetin protects against neuronal toxicity by activating the PI3K/Akt/GSK-3β pathway in vivo models of MPTP-induced Parkinson's disease.
Methacrylated sericin/methacrylated hyaluronic acid composite microneedles with exosomes for diabetic wound healing.
Bacillus paralicheniformis-mediated gut microbiota promotes M2 macrophage polarization by inhibiting P38 MAPK signaling to alleviate necrotizing enterocolitis and apoptosis in mice.
Liyan Kaiyin Formula relieves reflux pharyngitis by regulating M1 macrophage polarization via the NF-κB/NLRP3 pathway.
Optimally Aligned Nerve Scaffolds with Sustained Astaxanthin Release Improve the Inflammatory Microenvironment through Mitophagy Activation.
p16INK4a downregulation alleviates temporomandibular joint osteoarthritis combined with type 2 diabetes by driving M2 polarization.
β-Glucuronidase-Expressing Lactobacillus reuteri Triggers Irinotecan Enterotoxicity Through Depleting the Regenerative Epithelial Stem/Progenitor Pool.
Evidence for imbalanced polarization of caruncle macrophages in retained placenta of dairy cows.
Adipose Mesenchymal Stem Cells Derived Exosomes Ameliorates KOA Cartilage Damage and Inflammation by Activation of PINK1-Mediated Mitochondrial Autophagy.
miR-708-5p Attenuates Osteoarthritis Progression via Multi-Target Modulation of the NOX4/NF-κB Axis and Cartilage Homeostasis.
Salvianolic Acid B Attenuates Liver Fibrosis via Suppression of Glycolysis-Dependent m1 Macrophage Polarization.
A cell-free SHED lysate-hydrogel system for oral ulcer healing with anti-inflammatory and pro-angiogenic effects.
Deficiency of inducible nitric oxide synthase (iNOS) enhances MC903-induced atopic dermatitis-like inflammation in mice.
Activation of Hippocampal ACE2 Prevents the Dysbiosis-induced Depression-like Behavior in Mice by Enhanced Neurogenesis and Neuroprotection via Mas Receptor.
Urine-derived stem cells from patients alleviate lupus nephritis via regulating macrophage polarization in a CXCL14-dependent manner.
A Zinc-Citrate Metal-Organic Framework-Based Adaptable Hydrogen Sulfide Delivery System for Regulating Neuroregeneration Microenvironment in Spinal Cord Injury.
RNA-seq shows Angiopoietin-like 4 promotes hepatocellular carcinoma progression by inducing M2 polarization of tumor-associated macrophages.
Immunomodulatory and osteogenic effects of chitosan-based injectable hydrogel with geniposide-loaded mesoporous bioactive glass.
ROS Responsive Cerium Oxide Biomimetic Nanoparticles Alleviates Calcium Oxalate Crystals Induced Kidney Injury via Suppressing Oxidative Stress and M1 Macrophage Polarization.
Pimpinellin mitigates DSS-induced ulcerative colitis in mice by reducing inflammation and regulating gut microbiota.
Xibining inhibition of the PI3K-AKT pathway reduces M1 macrophage polarization to ameliorate KOA synovial inflammation and nociceptive sensitization.
Cannabidiol regulates L-carnitine and butyric acid metabolism by modulating the gut microbiota to ameliorate collagen-induced arthritis.
Hyperlipidemia exacerbates acute pancreatitis via interactions between P38MAPK and oxidative stress.
DLK1 regulates periodontal inflammation by inhibiting NF-κB p65 and JNK signaling pathways.
Administration of 2-deoxy-D-glucose alleviates cancer-induced bone pain by suppressing microglial polarization to the M1 phenotype and neuroinflammation.
Inhibition of macrophage polarization and pyroptosis in collagen-induced arthritis through MSC-exo and ginsenoside Rh2.
Pterostilbene protects against lipopolysaccharide-induced inflammation and blood-brain barrier disruption in immortalized brain endothelial cell lines in vitro.
A Disintegrin and Metalloproteinase 17 Disrupts Bovine Macrophage MER Proto-Oncogene Tyrosine Kinase Integrity to Impede Apoptotic Cell Clearance and Promote Inflammation in Clinical Mastitis.
Ultrasound-Triggered Nanogel Boosts Chemotherapy and Immunomodulation in Colorectal Cancer.
SIX1 aggravates the progression of spinal cord injury in mice by promoting M1 polarization of microglia.
Natural phenol carbamates: Selective BuChE/FAAH dual inhibitors show neuroprotection in an Alzheimer's disease mouse model.
The structural features and anti-inflammatory properties of a glucogalactan from Holotrichia diomphalia Bates (Qi Cao).
ROS-regulated SUR1-TRPM4 drives persistent activation of NLRP3 inflammasome in microglia after whole-brain radiation.
Positive feedback loop involving AMPK and CLYBL acetylation links metabolic rewiring and inflammatory responses.
Zinc-induced photocrosslinked konjac glucomannan/glycyrrhizic acid hydrogel promotes skin wound healing in diabetic mice through immune regulation.
iNOS-Produced Nitric Oxide from Cancer Cells as an Intermediate of Stemness Regulation by PARP-1 in Colorectal Cancer.
Luteolin modulates macrophage phenotypic switching via the AMPK-PPARγ pathway to alleviate ulcerative colitis in mice.
Dentin tubules as a long-term sustained release carrier to accelerate bone repair by loading FTY720.
Gut commensal bacteria Parabacteroides goldsteinii-derived outer membrane vesicles suppress skin inflammation in psoriasis.
Silk-engineered bioactive nanoparticles for targeted alleviation of acute inflammatory disease via macrophage reprogramming.
Hyperactivity of the IL-33-ILC2s-IL-13-M-MDSCs axis promotes cervical cancer progression.
N 6-Methyladenosine Demethylase FTO Controls Macrophage Homeostasis in Diabetic Vasculopathy.
Using chondroitin sulfate lithium hydrogel for diabetic bone regeneration via regulation of macrophage polarization.
Macrophage metabolic reprogramming ameliorates diabetes-induced microvascular dysfunction.
Network pharmacology and animal experiments revealed the protective effects of Guilong prescription on chronic prostatitis and its possible mechanisms.
Suramin enhances proliferation, migration, and tendon gene expression of human supraspinatus tenocytes.
Long-term treatment with the streptococcal exotoxin streptolysin O inhibits vascular smooth muscle contraction by inducing iNOS expression in endothelial cells.
Functionalized Nanozyme Microcapsules Targeting Deafness Prevention via Mitochondrial Homeostasis Remodeling.
Programmed surface platform orchestrates anti-bacterial ability and time-sequential bone healing for implant-associated infection.
ZIP8 Regulates Inflammation and Macrophage Polarisation in Intervertebral Disc Degeneration via the Wnt/β-Catenin Pathway.
Stigmasterol from Prunella vulgaris L. Alleviates LPS-induced mammary gland injury by inhibiting inflammation and ferroptosis.
Demyelination of the amygdala mediates psychological stress-induced emotional disorders partially contributed by activation of P2X7R/NLRP3 cascade.
Phillyrin ameliorates DSS-induced colitis in mice via modulating the gut microbiota and inhibiting the NF-κB/MLCK pathway.
Bioactive Decellularized Extracellular Matrix Platform Integrating Multifunctional Nanozymes and Cell-Laden Microgels for Acute Liver Failure Treatment.
ITIH5-mediated fibroblast/macrophage crosstalk exacerbates cardiac remodelling after myocardial infarction.
Dapagliflozin alleviated seizures and cognition impairment in pilocarpine induced status epilepticus via suppressing microglia-mediated neuroinflammation and oxidative stress.
MiR-186-5p carried by M2 macrophage-derived exosomes downregulates TRPP2 expression in airway smooth muscle to alleviate asthma progression.
TREM2 Alleviates Neuroinflammation by Maintaining Cellular Metabolic Homeostasis and Mitophagy Activity During Early Inflammation.
Micheliolide attenuates sepsis-induced acute lung injury by suppressing mitochondrial oxidative stress and PFKFB3-driven glycolysis.
Intelligent sequential degradation hydrogels by releasing bimetal-phenolic for enhanced diabetic wound healing.
Reactive Oxygen Species-Responsive Gel-Based Microneedle Patches with Antimicrobial and Immunomodulating Properties for Oral Mucosa Disease Treatment.
Carboxymethyl chitosan and sodium alginate oxide pH-sensitive dual-release hydrogel for diabetes wound healing: The combination of astilbin liposomes and diclofenac sodium.
AEBP1 targets DDR2 to induce ferroptosis and microglial activation through the STAT3/P53 signaling pathway, exacerbating depression risk.
WWP2 Overexpression Represses NLRP3 Inflammasome Activation in Cerebral Ischemia/Reperfusion Injury Through the Degradation of MAVS.
Uncovering the mechanistic basis of Rheum palmatum L. (rhubarb) in the treatment of chronic kidney disease: an integrative approach using network pharmacology, molecular docking, and experimental validation.
PINK1 overexpression suppresses p38 MAPK/NF‑κB signaling to attenuate chondrocyte senescence in osteoarthritis.
Self-assembled hybrid hydrogel microspheres create a bone marrow-mimicking niche for bone regeneration.
Baicalein alleviates long-term cognitive impairments induced by repeated neonatal sevoflurane exposure via inhibition of cortical microglial TLR4/NF-kB signaling.
Activating Ferroptosis of M1 Macrophages: A Novel Mechanism of Asiaticoside Encapsuled in GelMA for Anti-Inflammation in Diabetic Wounds.
AR Deficiency Protects Against Sepsis-Induced Acute Lung Injury by Inhibiting Macrophage M1 Polarization and Inflammatory Cytokine Secretion.
Inhibition of Macrophage Activation by Minocycline Attenuates CCI-Induced Neuropathic Pain.
Genetic Ablation of miR-146a Induces Abdominal Aortic Aneurysm Formation by Intensifying Inflammatory M1-Like Macrophages Polarization and Vascular Smooth Muscle Cell Phenotypic Switching.
Intelligent responsive PVA hydrogel loaded with composite MXene nanozyme enables efficient myocardial infarction repair by disrupting the oxidative stress-inflammation cascade.
Succinate Promotes M1 Polarization of Intestinal Macrophages in Mice With Necrotizing Enterocolitis Through the PI3K/AKT Pathway.
Dauricine Inhibits Macrophages M2 Polarization and Regulates the Progression and Ferroptosis via HCK/IDO1 in Urinary Bladder Cancer.
Size Effect of Mesoporous Bioactive Glass on Macrophage Polarization.
Vasoactive Effects of Chronic Treatment with ACE Inhibitor Zofenopril in Zucker Obese Diabetic Rats: The Role of Nitroso and Sul?de Signalization.
N-acetylcysteine Restores Impaired Dentate Gyrus Neurogenesis in a Neonatal Maternal Separation Rat Model.
Comparative evaluation of the therapeutic efficacy between human amniotic epithelial cells and human umbilical cord mesenchymal stem cells in premature ovarian insufficiency.
Sirtuin 3 promotes osteogenic differentiation of bone marrow mesenchymal stem cells by regulating macrophage polarization under high glucose.
Enhanced therapeutic efficacy of repeated bone marrow-derived MSC administration in a murine model of pulmonary fibrosis.
Exosome-mediated modulation of macrophage polarization and inflammation in early Klebsiella pneumoniae lung infections.
Decoding SDCBP's role in tumor progression and immune cells infiltration: from databases to macrophage validation.
Human OCEL1 senses bacterial infection to unlock inflammatory responses.
Genetic deletion of TRPM8 channels restores microvascular function and mitigates chronic kidney disease progression.
Sappanone A Promotes Motor Function Recovery in Spinal Cord Injury Mice by Inhibiting Microglial M1 Polarization via Activation of the Keap1/Nrf2 Pathway.
Fennel essential oil and its nanoemulsion modulate macrophage-mediated inflammatory responses and promote pressure ulcer healing.
Circulating plasma exosomal miR-146b-5p regulates microglial-mediated neuroinflammation through the TRAF6/NF-κB signaling axis after intracerebral hemorrhage.
Cepharanthine alleviates lipopolysaccharide-induced acute lung injury through modulating macrophage polarization.
Nebulized M2 macrophage-derived nanovesicles for the treatment of explosion-induced acute lung injury.
GPR30 Inhibits Neuronal Apoptosis After Subarachnoid Hemorrhage by Activating the Wnt/β-Catenin Pathway in a m6A-dependent Manner.
Aberrant neuronal excitation promotes neuroinflammation in the primary motor cortex of ischemic stroke mice.
Edaravone ameliorates inflammation in ischemic stroke mouse by regulating the CYP1A1 pathway through gut microbiota.
Ethanol extract of Sauropus spatulifolius and its active constituents attenuate LPS-induced acute lung injury via NF-κB inhibition and Nrf2 activation.
Rescuing inflammatory microenvironment induced senescence via MgO immune mediated asymmetric short fibers for accelerating diabetic wound repair.
Polyphenol-based self-assembled nanoparticles treating uveitis by inflammation-oxidative stress suppression.
Alchemizing earth's legacy: Bismuth-engineered humic nanoparticles for IBD theranostics through mitochondrial anti-inflammation and sustained intestinal delivery.
Immunoregulatory function and anticancer effects of Polygonatum sibiricum polysaccharides against hepatic carcinoma via macrophage phenotype modulation.
Immunogenic cuproptosis in cancer immunotherapy via an in situ cuproptosis-inducing system.
Transcriptional responses to nitric oxide are widescale and source-dependent.
Heparanase inhibition mitigates bleomycin-induced pulmonary fibrosis in mice by reducing M2 macrophage polarization.
A TRPV1 agonist from the transcriptome profiling of Dipsastraea rotumana inhibits neuroinflammation in vivo through the NF-κB and MAPK pathways.
The Role of the cGAS/STING Pathway in Arsenic-Induced Neurotoxicity: Insights from the Crosstalk Between Astrocytes and Neurons.
Black phosphorus nanosheets promote neuronal differentiation of neural stem cells through adhesion and pinocytosis for spinal cord injury repair.
SAA1 deletion ameliorates cardiac injury after myocardial infarction by promoting macrophage transformation to reparative subtype.
β-Mangostin Attenuates TET2-Mediated DNA Demethylation of Prkcg in the Prevention of Intervertebral Disc Degeneration.
Elevated Histone Lactylation Mediates Ferroptosis Resistance in Endometriosis Through the METTL3-Regulated HIF1A/HMOX1 Signaling Pathway.
A prometabolite strategy inhibits cardiometabolic disease in an ApoE-/- murine model of atherosclerosis.
An Olsalazine-Loaded Hollow Mesoporous Prussian Blue/Polydopamine Nanozyme Alleviates Anxiety/Depression-like Behavior and Enhances Brain Neural Activity in Colitis Mice.
ULK1 Knockout Exacerbates Ischemia-Induced Microglial Dysfunction via TRAF6/NF-κB Signaling Pathway.
Exosomal miR-218 secreted from endothelial progenitor cells mitigates acute lung injury in sepsis mice by inhibiting HMGA1 in alveolar macrophages.
Solidago decurrens Lour. controls LPS-induced acute lung injury by reducing inflammatory responses and modulating the TLR4/NF-κB/NLRP3 signaling pathway.
Piezo1 promotes colitis progression by modulating the Nrf2/NF-κB/NLRP3 signaling pathway.
The bone marrow mesenchymal stem cells derived migrasomes induced by Titania nanotubes surface serve as chemotaxis effect for osteogenesis.
Preventive and therapeutic effects of Tanshinone IIA on spinal cord injury without radiographic abnormality by regulating microglial phenotype polarization.
Harnessing dual-channel probiotics to synergistically correct intestinal and vaginal dysbiosis after antibiotic disruption.
L-arginine synergistic with 5-fluorouracil intervenes in DNA damage repair via the DNA-PKcs/ATM/ATR pathway in hepatocellular carcinoma cells.
Multiomics integration analysis identifies tumor cell-derived MIF as a therapeutic target and potentiates anti-PD-1 therapy in osteosarcoma.
A Neutrophil Storage Pool in the Fetal Liver is the Principal Source of the Postnatal Neutrophil Surge.
Ergosterol from edible fungi: Enhancing fatty acid oxidation via CPT1A to protect against diabetic kidney disease.
Functional anti-inflammatory mesoporous silica nanoplatform for Synergistic and Targeted abdominal aortic aneurysm treatment.
Methylprednisolone Modulates the Tfr/Tfh ratio in EAE-Induced Neuroinflammation through the PI3K/AKT/FoxO1 and PI3K/AKT/mTOR Signalling Pathways.
Efficacy of electro-acupuncture at "Weizhong" (BL40) on macrophage polarization in rats with injured lumbar multifidus.
Kaempferol attenuates macrophage M1 polarization and liver fibrosis by inhibiting mitogen-activated protein kinase/nuclear factor κB signaling pathway.
Baicalin attenuated metabolic dysfunction-associated fatty liver disease by suppressing oxidative stress and inflammation via the p62-Keap1-Nrf2 signalling pathway in db/db mice.
Exosome-loaded tannic acid-thioctic acid hydrogel enhances wound healing in coagulation disorders.
An injectable responsive exosome-releasing hydrogel based on sodium alginate restores motor and bladder function by alleviating the injury microenvironment and facilitating distal nerve repair.
Lactoferrin-modified nanoemulsions enhance brain-targeting and therapeutic efficacy of arctigenin against Toxoplasma gondii-induced neuronal injury.
Total alkaloids from Thesium chinense inhibit lipopolysaccharide-induced respiratory inflammation by modulating Nrf2/NF-κB/NLRP3 signaling pathway.
Exploring the anti-inflammatory effects of Radix Curcumae essential oil in pulmonary sarcoidosis via the TLR4/MyD88/NF-κB pathway.
ErTao decoction alleviates liver fibrosis by suppressing STING-mediated macrophages and NLRP3 inflammasome activation.
LIPUS Promotes Calcium Oscillation and Enhances Calcium Dependent Autophagy of Chondrocytes to Alleviate Osteoarthritis.
CpG-Based Nanovaccines Enhance Ovarian Cancer Immune Response by Gbp2-Mediated Remodeling of Tumor-Associated Macrophages.
Reprogramming Lung Redox Homeostasis by NIR Driven Ultra-Small Pd Loaded Covalent Organic Framework Inhibits NF-κB Pathway for Acute Lung Injury Immunotherapy.
Electret-Inspired Charge-Injected Hydrogel for Scar-Free Healing of Bacterially Infected Burns Through Bioelectrical Stimulation and Immune Modulation.
Hybrid membranes-mediated biomimetic-nanoparticle carrying miR-665 for effective tumor treatment by remodeling tumor microenvironment.
Acid-resistant chemotactic DNA micromotors for probiotic delivery in inflammatory bowel disease.
The E3 ligase c-Cbl modulates microglial phenotypes and contributes to Parkinson's disease pathology.
Nicotinamide mononucleotide supplementation ameliorates testicular damage induced by ischemia-reperfusion through reshaping macrophage and neutrophil inflammatory properties.
Therapeutic potential of naturally derived carbon dots in sepsis-associated acute kidney injury.
Effect of Engineered Cyanobacterial Capsules on a Neurogenic Bladder after Spinal Cord Injury.
Vitamin D(3) alleviates intestinal injury in necrotizing enterocolitis and lipopolysaccharide-induced inflammatory response in dendritic cells in rats.
Hollow Bismuth Nanoparticle-Loaded Gelatin Hydrogel Regulates M2 Polarization of Macrophages to Promote Infected Wound Healing.
Breast cancer-derived CAV1 promotes lung metastasis by regulating integrin α6β4 and the recruitment and polarization of tumor-associated neutrophils.
N-Acetylcysteine Alleviates Depressive-Like Behaviors in Adolescent EAAC1(-/-) Mice and Early Life Stress Model Rats.
Exosomal SLC16A1-AS1-induced M2 macrophages polarization facilitates hepatocellular carcinoma progression.
Antioxidant Carbon Dots and Ursolic Acid Co-Encapsulated Liposomes Composite Hydrogel for Alleviating Adhesion Formation and Enhancing Tendon Healing in Tendon Injury.
Sphingosine Kinase 1 Aggravates Liver Fibrosis by Mediating Macrophage Recruitment and Polarization.
The Therapeutic Potential of Pristimerin in Osteoarthritis: Mechanistic Insights from in vitro and in vivo Studies.
Chuanxiong Renshen Decoction Inhibits Alzheimer's Disease Neuroinflammation by Regulating PPARγ/NF-κB Pathway.
Probucol mitigates high-fat diet-induced cognitive and social impairments by regulating brain redox and insulin resistance.
IRF2 Affects LPS- and IFN-γ-Induced Pro-Inflammatory Responses, Cell Viability, Migration and Apoptosis of Macrophages by Regulating IRG1.
Nrf2 Deficiency Exacerbates Parkinson's Disease by Aggravating NLRP3 Inflammasome Activation in MPTP-Induced Mouse Models and LPS-Induced BV2 Cells.
New Insights into Roles of IL-7R Gene as a Therapeutic Target Following Intracerebral Hemorrhage.
The role of the C5a-C5aR pathway in iron metabolism and gastric cancer progression.
Assembly of ceria-Nrf2 nanoparticles as macrophage-targeting ROS scavengers protects against myocardial infarction.
Protective effects of berbamine against arginase-1 deficiency-induced injury in human brain microvascular endothelial cells.
Neuron stress-related genes serve as new biomarkers in hypothalamic tissue following high fat diet.
L-arginine combination with 5-fluorouracil inhibit hepatocellular carcinoma cells through suppressing iNOS/NO/AKT-mediated glycolysis.
Quercetin ameliorates ulcerative colitis by restoring the balance of M2/M1 and repairing the intestinal barrier via downregulating cGAS‒STING pathway.
Circular RNA SCMH1 suppresses KMO expression to inhibit mitophagy and promote functional recovery following stroke.
Neutrophil-like pH-responsive pro-efferocytic nanoparticles improve neurological recovery by promoting erythrophagocytosis after intracerebral hemorrhage.
Genetically engineered electrospinning contributes to spinal cord injury repair by regulating the immune microenvironment.
Inhibition of PTEN promotes osteointegration of titanium implants in type 2 diabetes by enhancing anti-inflammation and osteogenic capacity of adipose-derived stem cells.
Dandelion-shaped strontium-gallium microparticles for the hierarchical stimulation and comprehensive regulation of wound healing.
Low-Dose LPS Modulates Microglia/Macrophages Phenotypic Transformation to Amplify Rehabilitation Effects in Chronic Spinal Cord Injured (CSCI) Mice.
Mer activation ameliorates nerve injury-induced neuropathic pain by regulating microglial polarization and neuroinflammation via SOCS3 in male rats.
Delivery of neurotrophin-3 by RVG-Lamp2b-modified mesenchymal stem cell-derived exosomes alleviates facial nerve injury.
Naringenin relieves paclitaxel-induced pain by suppressing calcitonin gene-related peptide signalling and enhances the anti-tumour action of paclitaxel.
Sestrin2 remedies neuroinflammatory response by inhibiting A1 astrocyte conversion via autophagy.
Oxysophoridine inhibits oxidative stress and inflammation in hepatic fibrosis via regulating Nrf2 and NF-κB pathways.
Wheel-Running Exercise Alleviates Anxiety-Like Behavior via Down-Regulating S-Nitrosylation of Gephyrin in the Basolateral Amygdala of Male Rats.
Isoquercetin Ameliorates Osteoarthritis via Nrf2/NF-κB Axis: An In Vitro and In Vivo Study.
Transcription factor EGR2 alleviates autoimmune uveitis via activation of GDF15 to modulate the retinal microglial phenotype.
A composite patch loaded with 2-Deoxy Glucose facilitates cardiac recovery after myocardial infarction via attenuating local inflammatory response.
Allantoin ameliorates dopaminergic neuronal damage in MPTP-induced Parkinson's disease mice via regulating oxidative damage, inflammation, and gut microbiota disorder.
Dietary nitrate maintains homeostasis of oxidative stress and gut microbiota to promote flap survival in type 2 diabetes mellitus rats.
Hypoxic microenvironment promotes diabetic wound healing by polarizing macrophages to the M2 phenotype in vivo.
Mesenchymal Stem Cells Regulate Microglial Polarization via Inhibition of the HMGB1/TLR4 Signaling Pathway in Diabetic Retinopathy.
Targeting Mitochondrial Oxidative Stress to Protect Against Preterm Birth and Fetal Brain Injury via Nrf2 Induction.
Sequential Targeted Enzyme-Instructed Self-Assembly Supramolecular Nanofibers to Attenuate Intervertebral Disc Degeneration.
Dehydrocostus Lactone Ameliorates LPS-Induced Acute Lung Injury by Inhibiting PFKFB3-Mediated Glycolysis.
Bioactivity-Oriented Separation of "Pepper Alkaloids" from Piper sintenense Hatusima with Potential Antigouty Arthritis Activity.
Mutation of Pseudomonas aeruginosa lasI/rhlI diminishes its cytotoxicity, oxidative stress, inflammation, and apoptosis on THP-1 macrophages.
Erjingpill bionic cerebrospinal fluid alleviates LPS-induced inflammatory response in BV2 cells by inhibiting glycolysis via mTOR.
ACOD1 mediates Staphylococcus aureus-induced inflammatory response via the TLR4/NF-κB signaling pathway.
Morin alleviates DSS-induced ulcerative colitis in mice via inhibition of inflammation and modulation of intestinal microbiota.
Leukocyte infiltration and cross-talk with cardiomyocytes exploit intracellular stress pathways in dilated cardiomyopathy of idiopathic origin.
Ouabain Ameliorates Alzheimer's Disease-Associated Neuropathology and Cognitive Impairment in FAD(4T) Mice.
Oxygen Glucose Deprivation-Induced Lactylation of H3K9 Contributes to M1 Polarization and Inflammation of Microglia Through TNF Pathway.
Intermittent fasting attenuates cognitive dysfunction and systemic disease activity in mice with neuropsychiatric systemic lupus erythematosus.
Peptide TaY Attenuates Inflammatory Responses by Interacting with Myeloid Differentiation 2 and Inhibiting NF-κB Signaling Pathway.
LysoPE mediated by respiratory microorganism Aeromicrobium camelliae alleviates H9N2 challenge in mice.
Crystalline silica-induced endoplasmic reticulum stress promotes the pathogenesis of silicosis by augmenting proinflammatory interstitial pulmonary macrophages.
Vitexin Inhibits TNBC Progression and Metastasis by Modulating Macrophage Polarization Through EGFR Signaling.
Silencing ARL11 relieved atherosclerotic inflammation and lipid deposition via retraining JAK2/STAT1 pathway.
The role of phlorizin liposome-embedded oxidized sodium alginate/carboxymethyl chitosan in diabetic wound healing.
An Engineered Hierarchical Hydrogel with Immune Responsiveness and Targeted Mitochondrial Transfer to Augmented Bone Regeneration.
Taurine Inhibits Lung Metastasis in Triple-Negative Breast Cancer by Modulating Macrophage Polarization Through PTEN-PI3K/Akt/mTOR Pathway.
Hexokinase 2 senses fructose in tumor-associated macrophages to promote colorectal cancer growth.
Protective Effects of L-Cysteine Against Cisplatin-Induced Oxidative Stress-Mediated Reproductive Damage.
Mesenchymal stromal cells deliver H(2)S-enhanced Nrf2 via extracellular vesicles to mediate mitochondrial homeostasis for repairing hypoxia-ischemia brain damage.
Biliverdin improved angiogenesis and suppressed apoptosis via PI3K/Akt-mediated Nrf2 antioxidant system to promote ischemic flap survival.
Exploring the role of iNOS in HFpEF-Related myocardial fibrosis: Involvement of PTEN-PI3K/AKT signaling pathway.
HMGB1 Modulates Macrophage Metabolism and Polarization in Ulcerative Colitis by Inhibiting Cpt1a Expression.
Compound (E)-2-(3,4-dihydroxystyryl)-3-hydroxy-4H-pyran-4-one downregulation of Galectin-3 ameliorates Aβ pathogenesis-induced neuroinflammation in 5 × FAD mice.
Astragaloside IV promotes cerebral tissue restoration through activating AMPK- mediated microglia polarization in ischemic stroke rats.
Phillyrin: A potential therapeutic agent for osteoarthritis via modulation of NF-κB and Nrf2 signaling pathways.
PLGA microspheres carrying EMSCs-CM for the effective treatment of murine ulcerative colitis.
STING orchestrates microglia polarization via interaction with LC3 in autophagy after ischemia.
Diquat exacerbates oxidative stress and neuroinflammation by blocking the autophagic flux of microglia in the hippocampus.
Treatment of silicosis with quercetin depolarizing macrophages via inhibition of mitochondrial damage-associated pyroptosis.
Macrophage M2 polarization promotes pulpal inflammation resolution during orthodontic tooth movement.
Early postnatal moderate catch‑up growth in rats with nutritional intrauterine growth restriction preserves pulmonary vascular and cognitive function in adulthood.
Polarization to M1-type microglia in the hippocampus is involved in depression-like behavior in a mouse model of olfactory dysfunction.
Upregulation of Nrf2 signaling: A key molecular mechanism of Baicalin's neuroprotective action against diabetes-induced cognitive impairment.
3D Printing of a Vascularized Mini-Liver Based on the Size-Dependent Functional Enhancements of Cell Spheroids for Rescue of Liver Failure.
The Sirtuin 5 Inhibitor MC3482 Ameliorates Microglia‑induced Neuroinflammation Following Ischaemic Stroke by Upregulating the Succinylation Level of Annexin-A1.
Protective Effects of an Oligo-Fucoidan-Based Formula against Osteoarthritis Development via iNOS and COX-2 Suppression following Monosodium Iodoacetate Injection.
IGF2BP2 regulates the inflammation of fibroblast-like synoviocytes via GSTM5 in rheumatoid arthritis.
Resveratrol-loaded sulfated Hericium erinaceus β-glucan-chitosan nanoparticles: Preparation, characterization and synergistic anti-inflammatory effects.
S100A12 is involved in the pathology of osteoarthritis by promoting M1 macrophage polarization via the NF-κB pathway.
Inhibiting the NLRP3 Inflammasome with MCC950 Alleviates Neurological Impairment in the Brain of EAE Mice.
Quercetin-3-O-β-D-glucuronide attenuates osteoarthritis by inhibiting cartilage extracellular matrix degradation and inflammation.
A potential mechanism clue to the periodic storm from microglia activation and progressive neuron damage induced by paraquat exposure.
Hippocampal and gut AMPK activation attenuates enterocolitis-like symptoms and co-occurring depressive-like behavior in ulcerative colitis model mice: Involvement of brain-gut autophagy.
A Biomimetic Se-nHA/PC Composite Microsphere with Synergistic Immunomodulatory and Osteogenic Ability to Activate Bone Regeneration in Periodontitis.
Radix Bupleuri aqueous extract attenuates MK801-induced schizophrenia-like symptoms in mice: Participation of intestinal flora.
Bredigite-Based Bioactive Nerve Guidance Conduit for Pro-Healing Macrophage Polarization and Peripheral Nerve Regeneration.
Flexible Organic Photovoltaic-Powered Hydrogel Bioelectronic Dressing With Biomimetic Electrical Stimulation for Healing Infected Diabetic Wounds.
Boosting Microglial Lipid Metabolism via TREM2 Signaling by Biomimetic Nanoparticles to Attenuate the Sevoflurane-Induced Developmental Neurotoxicity.
LDL-Binding IL-10 Reduces Vascular Inflammation in Atherosclerotic Mice.
The Effect of Salvianolic Acid A on Tumor-Associated Macrophage Polarization and Its Mechanisms in the Tumor Microenvironment of Triple-Negative Breast Cancer.
A novel microglia-targeting strategy based on nanoparticle-mediated delivery of miR-26a-5p for long-lasting analgesia in chronic pain.
Cluster of Differentiation-44-Targeting Prussian Blue Nanoparticles Onloaded with Colchicine for Atherosclerotic Plaque Regression in a Mice Model.
Atrazine exposure promotes cardiomyocyte pyroptosis to exacerbate cardiotoxicity by activating NF-κB pathway.
Human amniotic MSCs-mediated anti-inflammation of CD206(hi)IL-10(hi) macrophages alleviates isoproterenol-induced ventricular remodeling in mice.
Wuling capsule modulates macrophage polarization by inhibiting the TLR4-NF-κB signaling pathway to relieve liver fibrosis.
SAP130 released by ferroptosis tubular epithelial cells promotes macrophage polarization via Mincle signaling in sepsis acute kidney injury.
The Anti-Atherosclerotic Effects of Buyang Huanwu Decoction through M1 and M2 Macrophage Polarization in an ApoE Knockout Mouse Model.
Ponicidin-induced conformational changes of HSP90 regulates the MAPK pathway to relieve ulcerative colitis.
MST1 knockdown inhibits osteoarthritis progression through Parkin-mediated mitophagy and Nrf2/NF-κB signalling pathway.
Dihydroquercetin alleviates dopamine neuron loss via regulating TREM2 activation.
Dual-crosslinking gelatin-hyaluronic acid methacrylate based biomimetic PDAC desmoplastic niche enhances tumor-associated macrophages recruitment and M2-like polarization.
CircRNA CDR1as affects functional repair after spinal cord injury and regulates fibrosis through the SMAD pathway.
POSTN knockdown suppresses IL-1β-induced inflammation and apoptosis of nucleus pulposus cells via inhibiting the NF-κB pathway and alleviates intervertebral disc degeneration.
The antidepressant effects of protein arginine methyltransferase 2 involve neuroinflammation.
PPARG-mediated autophagy activation alleviates inflammation in rheumatoid arthritis.
Exosomes from adipose-derived stem cells regulate macrophage polarization and accelerate diabetic wound healing via the circ-Rps5/miR-124-3p axis.
NIR triggered polydopamine coated cerium dioxide nanozyme for ameliorating acute lung injury via enhanced ROS scavenging.
Chishao - Fuzi herbal pair restore the macrophage M1/M2 balance in acute-on-chronic liver failure.
Programmed cell death factor 4-mediated hippocampal synaptic plasticity is involved in early life stress and susceptibility to depression.
Macrophage biomimetic nanoparticle-targeted functional extracellular vesicle micro-RNAs revealed via multiomics analysis alleviate sepsis-induced acute lung injury.
Potential Molecular Mechanism of Illicium simonsii Maxim Petroleum Ether Fraction in the Treatment of Hepatocellular Carcinoma.
Involvement of P2X7R-mediated microglia polarization and neuroinflammation in the response to electroacupuncture on post-stroke memory impairment.
Cathelicidin-BF regulates the AMPK/SIRT1/NF-κB pathway to ameliorate murine osteoarthritis: In vitro and in vivo studie.
Role of plasmacytoid dendritic cells in vascular dysfunction in mice with renovascular hypertension.
Integrated network pharmacology and pharmacological investigations to explore the potential mechanism of Ding-Chuan-Tang against chronic obstructive pulmonary disease.
ATF4 Contributes to Abdominal Aortic Aneurysm Formation via Modulating M1 Macrophage Polarization and Inflammation.
Sr-Incorporated Bioactive Glass Remodels the Immunological Microenvironment by Enhancing the Mitochondrial Function of Macrophage via the PI3K/AKT/mTOR Signaling Pathway.
Calcitriol attenuates lipopolysaccharide-induced neuroinflammation and depressive-like behaviors by suppressing the P2X7R/NLRP3/caspase-1 pathway.
Inonotus obliquus (Chaga) against HFD/STZ-induced glucolipid metabolism disorders and abnormal renal functions by regulating NOS-cGMP-PDE5 signaling pathway.
Huangqin decoction attenuates spared nerve injury (SNI)-induced neuropathic pain by modulating microglial M1/M2 polarization partially mediated by intestinal nicotinamide metabolism.
The cGAS/STING signaling pathway is involved in sevoflurane induced neuronal necroptosis via regulating microglia M1 polarization.
Myeloid-derived growth factor ameliorates dextran sodium sulfate-induced colitis by regulating macrophage polarization.
Nonswellable Hydrogel Patch with Tissue-Mimetic Mechanical Characteristics Remodeling In Vivo Microenvironment for Effective Adhesion Prevention.
Acetyl-11-keto-β-boswellic acid restrains the progression of synovitis in osteoarthritis via the Nrf2/HO-1 pathway.
Biomimetic NO Scavenging Hyaluronic Acid Nanoparticles Enable Targeted Delivery of MTX and Integrated Management of Rheumatoid Arthritis.
Sestrin2 Restricts Endothelial-to-Mesenchymal Transition Induced by Lipolysaccharide via Autophagy.
A Comparative Study of the Stability, Transport, and Structure-Activity Relationship of Round Scad Derived Peptides with Antineuroinflammatory Ability.
Multifunctional Microneedle Patch Based on Metal-Phenolic Network with Photothermal Antimicrobial, ROS Scavenging, Immunomodulatory, and Angiogenesis for Programmed Treatment of Diabetic Wound Healing.
Pain Relief, Functional Recovery, and Chondroprotective Effects of Angelica gigas Nakai in Osteoarthritis Due to Its Anti-Inflammatory Property: An In Vitro and In Vivo Study.
Zhen-wu-tang protects against myocardial fibrosis by inhibiting M1 macrophage polarization via the TLR4/NF-κB pathway.
Exploring the Mechanism of Asiatic Acid against Atherosclerosis Based on Molecular Docking, Molecular Dynamics, and Experimental Verification.
Adipose-derived stem cell exosomes loaded with icariin alleviates rheumatoid arthritis by modulating macrophage polarization in rats.
Effects and underlying mechanism of micro-nano-structured zirconia surfaces on biological behaviors of human gingival fibroblasts under inflammatory conditions.
Shape-fixing hydrogel promotes scarless healing of wounds under tension.
MSCs-exosomes can promote macrophage M2 polarization via exosomal miR-21-5p through Mesenteric injection: a promising way to attenuate murine colitis.
A Blend of Tamarindus Indica and Curcuma Longa Extracts Alleviates Monosodium Iodoacetate (MIA)-Induced Osteoarthritic Pain and Joint Inflammation in Rats.
Anti-inflammatory activities of several diterpenoids isolated from Hemionitis albofusca.
STING modulates iron metabolism to promote liver injury and inflammation in acute immune hepatitis.
NRF2 interacts with distal enhancer and inhibits nitric oxide synthase 2 expression in KRAS-driven pancreatic cancer cells.
Ganoderic acid A slows osteoarthritis progression by attenuating endoplasmic reticulum stress and blocking NF-Κb pathway.
Mitochondria-derived peptide is an effective target for treating streptozotocin induced painful diabetic neuropathy through induction of activated protein kinase/peroxisome proliferator-activated receptor gamma coactivator 1alpha -mediated mitochondrial biogenesis.
Danggui-Shaoyao-San (DSS) ameliorates the progression of osteoarthritis via suppressing the NF-κB signaling pathway: an in vitro and in vivo study combined with bioinformatics analysis.
Liriodendrin exerts protective effects against chronic endometritis in rats by modulating gut microbiota composition and the arginine/nitric oxide metabolic pathway.
PCSK9 inhibitor protects against ischemic cerebral injury by attenuating inflammation via the GPNMB/CD44 pathway.
Adipose-derived stem cell exosomes promote tumor characterization and immunosuppressive microenvironment in breast cancer.
κ-Opioid receptor activation attenuates osteoarthritis synovitis by regulating macrophage polarization through the NF-κB pathway.
Rosmarinic acid against cognitive impairment via RACK1/HIF-1α regulated microglial polarization in sepsis-surviving mice.
Gypenoside XLIX attenuates sepsis-induced splenic injury through inhibiting inflammation and oxidative stress.
The protective effect of Ergolide in osteoarthritis: In vitro and in vivo studies.
Liensinine alleviates mouse intestinal injury induced by sepsis through inhibition of oxidative stress, inflammation, and cell apoptosis.
Rutin prevents pyroptosis and M1 microglia via Nrf2/Mac-1/caspase-1-mediated inflammasome axis to improve POCD.
Comparison of the inhibition effects of naringenin and its glycosides on LPS-induced inflammation in RAW 264.7 macrophages.
METTL14 contributes to acute lung injury by stabilizing NLRP3 expression in an IGF2BP2-dependent manner.
Modified Simiaowan prevents and treats gouty arthritis via the Nrf2/NLRP3 inflammasome signaling pathway.
TREM2 regulates BV2 microglia activation and influences corticosterone-induced neuroinflammation in depressive disorders.
Activation of LXRs alleviates neuropathic pain-induced cognitive dysfunction by modulation of microglia polarization and synaptic plasticity via PI3K/AKT pathway.
Alisol A Exerts Neuroprotective Effects Against HFD-Induced Pathological Brain Aging via the SIRT3-NF-κB/MAPK Pathway.
Caffeic acid alleviates cerebral ischemic injury in rats by resisting ferroptosis via Nrf2 signaling pathway.
METTL3 promotes microglial inflammation via MEF2C in spinal cord injury.
Targeted transplantation of engineered mitochondrial compound promotes functional recovery after spinal cord injury by enhancing macrophage phagocytosis.
Reprogramming macrophages via immune cell mobilized hydrogel microspheres for osteoarthritis treatments.
A dihydromyricetin-loaded phellinus igniarius polysaccharide/l-arginine modified chitosan-based hydrogel for promoting wound recovery in diabetic mice via JNK and TGF-β/Smad signaling pathway.
The mechanism of adipose mesenchymal stem cells to stabilize the immune microenvironment of pelvic floor injury by regulating pyroptosis and promoting tissue repair.
In vitro and in vivo biological evaluation of Lappaconitine derivatives as potential anti-inflammatory agents.
Early life stress enhances the susceptibility to depression and interferes with neuroplasticity in the hippocampus of adolescent mice via regulating miR-34c-5p/SYT1 axis.
Aerobic Glycolysis Induced by mTOR/HIF-1α Promotes Early Brain Injury After Subarachnoid Hemorrhage via Activating M1 Microglia.
Arteannuin B, a sesquiterpene lactone from Artemisia annua, attenuates inflammatory response by inhibiting the ubiquitin-conjugating enzyme UBE2D3-mediated NF-κB activation.
PPM1G regulates hepatic ischemia/reperfusion injury through STING-mediated inflammatory pathways in macrophages.
A Novel Cargo Delivery System-AnCar-Exo(LaIMTS) Ameliorates Arthritis via Specifically Targeting Pro-Inflammatory Macrophages.
TNF-α Levels Are Increased in Patients with Subjective Cognitive Impairment and Are Negatively Correlated with β Amyloid-42.
Fabrication of levofloxacin-loaded porcine acellular dermal matrix hydrogel and functional assessment in urinary tract infection.
Multipathway Regulation for Targeted Atherosclerosis Therapy Using Anti-miR-33-Loaded DNA Origami.
Cathepsin B-Responsive Programmed Brain Targeted Delivery System for Chemo-Immunotherapy Combination Therapy of Glioblastoma.
Elucidating the mechanisms of formononetin in modulating atherosclerotic plaque formation in ApoE-/- mice.
The Pea Oligosaccharides Could Stimulate the In Vitro Proliferation of Beneficial Bacteria and Enhance Anti-Inflammatory Effects via the NF-κB Pathway.
YTHDF2 alleviates microglia activation via promoting circHIPK2 degradation.
TRIM65 knockout inhibits the development of HCC by polarization tumor-associated macrophages towards M1 phenotype via JAK1/STAT1 signaling pathway.
An Amino Acids and Dipeptide Injection Inhibits the TNF-α/HMGB1 Inflammatory Signaling Pathway to Reduce Pyroptosis and M1 Microglial Polarization in POCD Mice: the Gut to the Brain.
Microglial EPOR Contribute to Sevoflurane-induced Developmental Fine Motor Deficits Through Synaptic Pruning in Mice.
Oxyresveratrol reduces lipopolysaccharide-induced inflammation and oxidative stress through inactivation of MAPK and NF-κB signaling in brain endothelial cells.
Esculin Alleviates Osteoarthritis Progression Through the Sirt1/NF-κB Pathway.
An injectable self-lubricating supramolecular polymer hydrogel loaded with platelet lysate to boost osteoarthritis treatment.
Engineering of phosphatidylserine-targeting ROS-responsive polymeric prodrug for the repair of ischemia-reperfusion-induced acute kidney injury.
TBK1 is involved in M-CSF-induced macrophage polarization through mediating the IRF5/IRF4 axis.
An advanced chitosan based sponges dressing system with antioxidative, immunoregulation, angiogenesis and neurogenesis for promoting diabetic wound healing.
Injectable hyaluronate-based hydrogel with a dynamic/covalent dual-crosslinked architecture for bone tissue engineering: Enhancing osteogenesis and immune regulation.
Multifunctional carboxymethyl chitosan/oxidized carboxymethyl cellulose hydrogel loaded with ginsenoside Rg1 and polydopamine nanoparticles for infected diabetic wound healing.
Indole-3-Carboxaldehyde Inhibits Inflammatory Response and Lipid Accumulation in Macrophages Through the miR-1271-5p/HDAC9 Pathway.
S-Nitrosylation of NOTCH1 Regulates Mesenchymal Stem Cells Differentiation Into Hepatocyte-Like Cells by Inhibiting Notch Signalling Pathway.
Spatial dimension cues derived from fibrous scaffolds trigger mechanical activation to potentiate the paracrine and regenerative functions of MSCs via the FAK-PI3K/AKT axis.
Baliosperoid A attenuates lipopolysaccharide-induced acute lung injury by targeting SHP2 to inhibit inflammation and oxidative stress.
Targeted inhibition of Gus-expressing Enterococcus faecalis to promote intestinal stem cell and epithelial renovation contributes to the relief of irinotecan chemotoxicity by dehydrodiisoeugenol.
The active ingredient of Evodia rutaecarpa reduces inflammation in knee osteoarthritis rats through blocking calcium influx and NF-κB pathway.
Praelolide alleviates collagen-induced arthritis through increasing catalase activity and activating Nrf2 pathway.
Ultra-Long-Term Anti-Inflammatory Polyphenol Capsule to Remodel the Microenvironment for Accelerating Osteoarthritis Healing by Single Dosage.
Lycopodium japonicum Thunb. inhibits chondrocyte apoptosis, senescence and inflammation in osteoarthritis through STING/NF-κB signaling pathway.
Nuciferine ameliorates osteoarthritis: An in vitro and in vivo study.
Kongensin A targeting PI3K attenuates inflammation-induced osteoarthritis by modulating macrophage polarization and alleviating inflammatory signaling.
Long-term hypothermia amplified neuroprotection by antagonizing intracranial pressure rebound after severe traumatic brain injury in rats.
Evaluation of the Anti-Amyloid and Anti-Inflammatory Properties of a Novel Vanadium(IV)-Curcumin Complex in Lipopolysaccharides-Stimulated Primary Rat Neuron-Microglia Mixed Cultures.
Engineered Magneto-Piezoelectric Nanoparticles-Enhanced Scaffolds Disrupt Biofilms and Activate Oxidative Phosphorylation in Icam1(+) Macrophages for Infectious Bone Defect Regeneration.
Ibuprofen modulates macrophage polarization by downregulating poly (ADP-ribose) polymerase 1.
Tet2 modulates M2 macrophage polarization via mRNA 5-methylcytosine in allergic rhinitis.
Wedelolactone alleviates inflammation and cartilage degeneration by suppressing the NF-κB signaling pathway in osteoarthritis.
Sulforaphane potentiates the efficacy of chemoradiotherapy in glioblastoma by selectively targeting thioredoxin reductase 1.
Soyasaponin Bb/Gelatin-Methacryloyl Hydrogel for Cartilage Inflammation Inhibition.
Novel Glycyrrhetin Ureas Possessing 2-Hydroxy-3-enone A Ring: Modification, Anti-inflammatory Activity, and Targeted STING for the Remedy of Acute Kidney Injury.
Inhibition of LSD1 via SP2509 attenuated the progression of rheumatoid arthritis.
Auraptene Mitigates Colitis Induced by Dextran Sulfate Sodium in Mice by Regulating Specific Intestinal Flora and Repairing the Intestinal Barrier.
Fucoidan improving spinal cord injury recovery: Modulating microenvironment and promoting remyelination.
A gelatin methacryloyl (GelMA) treated with gallic acid and coated with specially designed nanoparticles derived from ginseng enhances the healing of wounds in diabetic rats.
Anti-ulcerative colitis effect of rotating magnetic field on DSS-induced mice by modulating colonic inflammatory deterioration.
Zwitterion-Lubricated Hydrogel Microspheres Encapsulated with Metformin Ameliorate Age-Associated Osteoarthritis.
Schisandrin B alleviates testicular inflammation and Sertoli cell apoptosis via AR-JNK pathway.
Quercetin-loaded Human Umbilical cord Mesenchymal Stem Cell-derived sEVs for Spinal Cord Injury Recovery.
Pterostilbene improves neurological dysfunction and neuroinflammation after ischaemic stroke via HDAC3/Nrf1-mediated microglial activation.
Investigation of the mechanism of baicalein in the treatment of periodontitis based on network pharmacology, molecular docking and experimental validation.
IL-1β mediates Candida tropicalis-induced immunosuppressive function of MDSCs to foster colorectal cancer.
Adipose-derived stem cell exosomes loaded with icariin attenuated M1 polarization of macrophages via inhibiting the TLR4/Myd88/NF-κB signaling pathway.
Effect of Scaffold Geometrical Structure on Macrophage Polarization during Bone Regeneration Using Honeycomb Tricalcium Phosphate.
Anti-atopic dermatitis effect of fraxinellone via inhibiting IL-31 in vivo and in vitro.
Arjunolic acid ameliorates lipopolysaccharide-induced depressive behavior by inhibiting neuroinflammation via microglial SIRT1/AMPK/Notch1 signaling pathway.
Gut dysbiosis contributes to SCFAs reduction-associated adipose tissue macrophage polarization in gestational diabetes mellitus.
SS-31 inhibits mtDNA-cGAS-STING signaling to improve POCD by activating mitophagy in aged mice.
Toll-like receptor 3 signaling drives enteric glial cells against dextran sulfate sodium-induced colitis in mice.
Single‐cell RNA sequencing reveals inflammatory retinal microglia in experimental autoimmune uveitis.
Asiaticoside ameliorates DSS-induced colitis in mice by inhibiting inflammatory response, protecting intestinal barrier and regulating intestinal microecology.
Biomimetic nano-chelate diethyldithiocarbamate Cu/Fe for enhanced metalloimmunity and ferroptosis activation in glioma therapy.
Liensinine reduces acute lung injury brought on by lipopolysaccharide by inhibiting the activation of the NF-κB signaling pathway through modification of the Src/TRAF6/TAK1 axis.
Platycodon grandiflorus polysaccharide inhibits the inflammatory response of 3D4/21 cells infected with PCV2.
Spermidine ameliorates osteoarthritis via altering macrophage polarization.
Cynaroside improved depressive-like behavior in CUMS mice by suppressing microglial inflammation and ferroptosis.
Tumor necrosis factor α-induced protein 8-like-2 controls microglia phenotype via metabolic reprogramming in BV2 microglial cells and responses to neuropathic pain.
5Z-7-Oxozaenol attenuates cuprizone-induced demyelination in mice through microglia polarization regulation.
Baohuoside I suppresses the NLRP3 inflammasome activation via targeting GPER to fight against Parkinson's disease.
Engineered Extracellular Vesicles Driven by Erythrocytes Ameliorate Bacterial Sepsis by Iron Recycling, Toxin Clearing and Inflammation Regulation.
Myricetin Oligomer Triggers Multi-Receptor Mediated Penetration and Autophagic Restoration of Blood-Brain Barrier for Ischemic Stroke Treatment.
Baicalin reduces inflammation to inhibit lung cancer via targeting SOCS1/NF-κB/STAT3 axis.
Electroacupuncture promotes macrophage/microglial M2 polarization and suppresses inflammatory pain through AMPK.
Tannic Acid-Modified Decellularized Tendon Scaffold with Antioxidant and Anti-Inflammatory Activities for Tendon Regeneration.
Network pharmacology and experimental validation of effects of total saponins extracted from Abrus cantoniensis Hance on acetaminophen-induced liver injury.
Mas receptor activation facilitates innate hematoma resolution and neurological recovery after hemorrhagic stroke in mice.
Chemotherapy-elicited extracellular vesicle CXCL1 from dying cells promotes triple-negative breast cancer metastasis by activating TAM/PD-L1 signaling.
Physalin H ameliorates LPS-induced acute lung injury via KEAP1/NRF2 axis.
Chrysin Inhibits TAMs-Mediated Autophagy Activation via CDK1/ULK1 Pathway and Reverses TAMs-Mediated Growth-Promoting Effects in Non-Small Cell Lung Cancer.
Baicalin Reduces Immune Cell Infiltration by Inhibiting Inflammation and Protecting Tight Junctions in Ischemic Stroke Injury.
P-Glycoprotein Exacerbates Brain Injury Following Experimental Cerebral Ischemia by Promoting Proinflammatory Microglia Activation.
Periventricular Microglia Polarization and Morphological Changes Accompany NLRP3 Inflammasome-Mediated Neuroinflammation after Hypoxic-Ischemic White Matter Damage in Premature Rats.
Identifying Macrophage-Related Genes in Ulcerative Colitis Using Weighted Coexpression Network Analysis and Machine Learning.
Ninjinyoeito Prevents Onset of Depression-Like Behavior and Reduces Hippocampal iNOS Expression in Senescence-Accelerated Mouse Prone 8 Mice.
Donor Mesenchymal Stem Cells Program Bone Marrow, Altering Macrophages, and Suppressing Endometriosis in Mice.
TREM-1 governs NLRP3 inflammasome activation of macrophages by firing up glycolysis in acute lung injury.
Up-Regulation of miR-9-5p Inhibits Hypoxia-Ischemia Brain Damage Through the DDIT4-Mediated Autophagy Pathways in Neonatal Mice.
Unveiling FOS as a Potential Diagnostic Biomarker and Emetine as a Prospective Therapeutic Agent for Diabetic Nephropathy.
Integrated Analysis of Non-Coding RNA and mRNA Expression Profiles in Exosomes from Lung Tissue with Sepsis-Induced Acute Lung Injury.
Activation of the microglial P2X7R/NLRP3 inflammasome mediates central sensitization in a mouse model of medication overuse headache.
FGL2 deficiency alleviates maternal inflammation-induced blood-brain barrier damage by blocking PI3K/NF-κB mediated endothelial oxidative stress.
PLEKHA4 is a novel prognostic biomarker that reshapes the tumor microenvironment in lower-grade glioma.
Norbergenin prevents LPS-induced inflammatory responses in macrophages through inhibiting NFκB, MAPK and STAT3 activation and blocking metabolic reprogramming.
Lycium barbarum polysaccharide alleviates dextran sodium sulfate-induced inflammatory bowel disease by regulating M1/M2 macrophage polarization via the STAT1 and STAT6 pathways.
Sialidase facilitates Porphyromonas gingivalis immune evasion by reducing M1 polarization, antigen presentation, and phagocytosis of infected macrophages.
Thermos-responsive hydrogel system encapsulated engineered exosomes attenuate inflammation and oxidative damage in acute spinal cord injury.
Tertiary Lymphoid Structures Are Related to Inflammatory Progression and Bone Loss in Human Apical Periodontitis.
Aβ Induces Neuroinflammation and Microglial M1 Polarization via cGAS-STING-IFITM3 Signaling Pathway in BV-2 Cells.
Gut microbiota-derived short-chain fatty acids promote prostate cancer progression via inducing cancer cell autophagy and M2 macrophage polarization.
Salidroside ameliorated the pulmonary inflammation induced by cigarette smoke via mitigating M1 macrophage polarization by JNK/c-Jun.
Notopterol alleviates the progression of osteoarthritis: An in vitro and in vivo study.
Caffeoylquinic acids isolated from Lonicera japonica Thunb. as TAK1 inhibitors protects against LPS plus IFN-γ-stimulated inflammation by interacting with KEAP1-regulated NRF2 activation.
Maslinic acid alleviates LPS-induced mice mastitis by inhibiting inflammatory response, maintaining the integrity of the blood-milk barrier and regulating intestinal flora.
NDUFC2 deficiency exacerbates endothelial mesenchymal transformation during ischemia-reperfusion via NLRP3.
A multifunctional polydopamine/genipin/alendronate nanoparticle licences fibrin hydrogels osteoinductive and immunomodulatory potencies for repairing bone defects.
Resveratrol alleviates DSS-induced IBD in mice by regulating the intestinal microbiota-macrophage-arginine metabolism axis.
Targeting STING-mediated pro-inflammatory and pro-fibrotic effects of alveolar macrophages and fibroblasts blunts silicosis caused by silica particles.
Activation of GABA receptor attenuates intestinal inflammation by modulating enteric glial cells function through inhibiting NF-κB pathway.
FKN secreted by kidney epithelial cells regulates macrophage activation in lupus nephritis via the Hippo signaling pathway.
Stem cell-derived hepatocyte therapy using versatile biomimetic nanozyme incorporated nanofiber-reinforced decellularized extracellular matrix hydrogels for the treatment of acute liver failure.
Cocktail of three isoquinoline alkaloids derived from Glaucium grandiflorum Boiss. & A. Huet subsp. refractum (Nábelek) Mory inhibits the production of LPS-induced ROS, pro-inflammatory cytokines, and mediators through the down-regulation of p38 MAPK in BV-2 cells.
Geniposide ameliorates atherosclerosis by regulating macrophage polarization via perivascular adipocyte-derived CXCL14.
Lactobacillus casei combined with Lactobacillus reuteri alleviate pancreatic cancer by inhibiting TLR4 to promote macrophage M1 polarization and regulate gut microbial homeostasis.
Bioinspired nanovesicles released from injectable hydrogels facilitate diabetic wound healing by regulating macrophage polarization and endothelial cell dysfunction.
Melatonin Protects Bovine Spermatozoa by Reinforcing Their Antioxidant Defenses.
Combined Lycium barbarum Polysaccharides with Plasmon-Activated Water Affect IFN-γ/TNF-α Induced Inflammation in Caco-2 Cells.
Attenuation of Chronic Stress-Induced Depressive-like Symptoms by Fish Oil via Alleviating Neuroinflammation and Impaired Tryptophan Metabolism in Aging Rats.
Oral administration of sophoricoside (SOP) inhibits neuronal damage and neuroinflammation to curb neurodegeneration in Parkinson's disease.
Umbilical cord mesenchymal stem cell-conditioned medium inhibits microglial activation to ameliorate neuroinflammation in amyotrophic lateral sclerosis mice and cell models.
Xanthohumol alleviates palmitate-induced inflammation and prevents osteoarthritis progression by attenuating mitochondria dysfunction/NLRP3 inflammasome axis.
GCH1 reduces LPS-induced alveolar macrophage polarization and inflammation by inhibition of ferroptosis.
Orientin inhibits inflammation in chondrocytes and attenuates osteoarthritis through Nrf2/NF-κB and SIRT6/NF-κB pathway.
Localized delivery of anti-inflammatory agents using extracellular matrix-nanostructured lipid carriers hydrogel promotes cardiac repair post-myocardial infarction.
Acetyl zingerone ameliorates osteoarthritis by inhibiting chondrocyte programmed cell death.
Dauricine regulates prostate cancer progression by inhibiting PI3K/AKT-dependent M2 polarization of macrophages.
Berberine ameliorates collagen-induced arthritis in mice by restoring macrophage polarization via AMPK/mTORC1 pathway switching glycolytic reprogramming.
The metabolite butyrate produced by gut microbiota inhibits cachexia-associated skeletal muscle atrophy by regulating intestinal barrier function and macrophage polarization.
Peroxisome proliferator-activated receptor gamma agonist pioglitazone alleviates hemorrhage-induced thalamic pain and neuroinflammation.
A natural sesquiterpene lactone isolinderalactone attenuates lipopolysaccharide-induced inflammatory response and acute lung injury through inhibition of NF-κB pathway and activation Nrf2 pathway in macrophages.
Pachymic acid suppresses the inflammatory response of chondrocytes and alleviates the progression of osteoarthritis via regulating the Sirtuin 6/NF-κB signal axis.
CTRP6 regulates M1 macrophage polarization via the PPAR-γ/NF-κB pathway and reprogramming glycolysis in recurrent spontaneous abortion.
Rabdosichuanin C inhibits productions of pro-inflammatory mediators regulated by NF-κB signaling in LPS-stimulated RAW264.7 cells.
Discovery of anti-neuroinflammatory agents from 1,4,5,6-tetrahydrobenzo[2,3]oxepino[4,5-d]pyrimidin-2-amine derivatives by regulating microglia polarization.
Dapagliflozin protects against doxorubicin-induced nephrotoxicity associated with nitric oxide pathway-A translational study.
Electroacupuncture Alleviates CFA-Induced Inflammatory Pain via PD-L1/PD-1-SHP-1 Pathway.
Cannabinoid type 2 receptor activation inhibits MPP(+)-induced M1 differentiation of microglia through activating PI3K/Akt/Nrf2 signal pathway.
TAK1 deficiency promotes liver injury and tumorigenesis via ferroptosis and macrophage cGAS-STING signalling.
Activation of glucagon-like peptide-1 receptor in microglia exerts protective effects against sepsis-induced encephalopathy via attenuating endoplasmic reticulum stress-associated inflammation and apoptosis in a mouse model of sepsis.
miR-26a-5p alleviates CFA-induced chronic inflammatory hyperalgesia through Wnt5a/CaMKII/NFAT signaling in mice.
Macrophage membrane-coated nanovesicles for dual-targeted drug delivery to inhibit tumor and induce macrophage polarization.
Delivery of coenzyme Q10 loaded micelle targets mitochondrial ROS and enhances efficiency of mesenchymal stem cell therapy in intervertebral disc degeneration.
TP53 mutation-related senescence is an indicator of hepatocellular carcinoma patient outcomes from multiomics profiles.
A low-salt diet with candesartan administration is associated with acute kidney injury in nephritis by increasing nitric oxide.
Baicalein ameliorates Alzheimer's disease via orchestration of CX3CR1/NF-κB pathway in a triple transgenic mouse model.
Echinacea Polyphenols Inhibit NLRP3-Dependent Pyroptosis, Apoptosis, and Necroptosis via Suppressing NO Production during Lipopolysaccharide-Induced Acute Lung Injury.
Apigenin Alleviates Autoimmune Uveitis by Inhibiting Microglia M1 Pro-Inflammatory Polarization.
Cigarette smoke induces the ROS accumulation and iNOS activation through deactivation of Nrf-2/SIRT3 axis to mediate the human bronchial epithelium ferroptosis.
Multiple low-dose radiation-induced neuronal cysteine transporter expression and oxidative stress are rescued by N-acetylcysteine in neuronal SH-SY5Y cells.
Lnc-17Rik promotes the immunosuppressive function of Myeloid-Derived suppressive cells in esophageal cancer.
miR-449a ameliorates acute rejection after liver transplantation via targeting procollagen-lysine1,2-oxoglutarate5-dioxygenase 1 in macrophages.
TMEM16F may be a new therapeutic target for Alzheimer's disease.
The antimicrobial peptide LK2(6)A(L) exhibits anti-inflammatory activity by binding to the myeloid differentiation 2 domain and protects against LPS-induced acute lung injury in mice.
Onychiol B attenuates lipopolysaccharide-induced inflammation via MAPK/NF-κB pathways and acute lung injury in vivo.
Garlic-derived exosomes carrying miR-396e shapes macrophage metabolic reprograming to mitigate the inflammatory response in obese adipose tissue.
Activation of HCA2 regulates microglial responses to alleviate neurodegeneration in LPS-induced in vivo and in vitro models.
Baicalin facilitates remyelination and suppresses neuroinflammation in rats with chronic cerebral hypoperfusion by activating Wnt/β-catenin and inhibiting NF-κB signaling.
Porcine Reproductive and Respiratory Syndrome Virus Modulates the Switch of Macrophage Polarization from M1 to M2 by Upregulating MoDC-Released sCD83.
Shared Genes of PPARG and NOS2 in Alzheimer's Disease and Ulcerative Colitis Drive Macrophages and Microglia Polarization: Evidence from Bioinformatics Analysis and Following Validation.
Corilagin ameliorates macrophages inflammation in atherosclerosis through TLR4-NFκB/MAPK pathway.
Dendritic cell-derived exosomal miR-3064-5p inhibits SIRT6/PCSK9 to protect the blood-brain barrier after subarachnoid hemorrhage.
Human umbilical cord blood mononuclear cells ameliorate ischemic brain injury via promoting microglia/macrophages M2 polarization in MCAO Rats.
A fully biodegradable polydioxanone occluder for ventricle septal defect closure.
Alpha-ketoglutarate promotes alveolar bone regeneration by modulating M2 macrophage polarization.
Celastrol-encapsulated microspheres prepared by microfluidic electrospray for alleviating inflammatory pain.
MFN2 deficiency affects calcium homeostasis in lung adenocarcinoma cells via downregulation of UCP4.
Isobavachalcone ameliorates the progression of osteoarthritis by suppressing NF-κB signaling pathway.
Celastrol-loaded biomimetic nanodrug ameliorates APAP-induced liver injury through modulating macrophage polarization.
Preparation of nanocomposite membranes loaded with taxifolin liposome and its mechanism of wound healing in diabetic mice.
Endothelial progenitor cell-derived exosomes promote anti-inflammatory macrophages via SOCS3/JAK2/STAT3 axis and improve the outcome of spinal cord injury.
Fusarium Mycotoxins Zearalenone and Deoxynivalenol Reduce Hepatocyte Innate Immune Response after the Listeria monocytogenes Infection by Inhibiting the TLR2/NFκB Signaling Pathway.
SENP3-mediated deSUMOylation of c-Jun facilitates microglia-induced neuroinflammation after cerebral ischemia and reperfusion injury.
The protective effects of Zhi-Gan-Cao-Tang against diabetic myocardial infarction injury and identification of its effective constituents.
Targeting of Annexin A1 in Tumor-associated Macrophages as a therapeutic strategy for hepatocellular carcinoma.
Suramin ameliorates osteoarthritis by acting on the Nrf2/HO-1 and NF-κB signaling pathways in chondrocytes and promoting M2 polarization in macrophages.
Selenium-Doped Mesoporous Bioactive Glass Regulates Macrophage Metabolism and Polarization by Scavenging ROS and Promotes Bone Regeneration In Vivo.
Induced neural stem cells suppressed neuroinflammation by inhibiting the microglial pyroptotic pathway in intracerebral hemorrhage rats.
Interleukin-1β Disruption Protects Male Mice From Heart Failure With Preserved Ejection Fraction Pathogenesis.
Pien Tze Huang attenuated acetaminophen-induced liver injury by autophagy mediated-NLRP3 inflammasome inhibition.
Crude polysaccharide from Danggui Buxue decoction enhanced the anti-tumor effect of gemcitabine by remodeling tumor-associated macrophages.
Adenosine kinase promotes post-infarction cardiac repair by epigenetically maintaining reparative macrophage phenotype.
IL-33/ST2 axis promotes remodeling of the extracellular matrix and drives protective microglial responses in the mouse model of perioperative neurocognitive disorders.
Dehydrocorydaline alleviates sleep deprivation-induced persistent postoperative pain in adolescent mice through inhibiting microglial P2Y(12) receptor expression in the spinal cord.
Peptide-anchored neutrophil membrane-coated biomimetic nanodrug for targeted treatment of rheumatoid arthritis.
Melatonin Attenuates Mitochondrial Damage in Aristolochic Acid-Induced Acute Kidney Injury.
Hypoxia-Inducible Factor-1α Protects Against Intervertebral Disc Degeneration Through Antagonizing Mitochondrial Oxidative Stress.
Castor1 overexpression regulates microglia M1/M2 polarization via inhibiting mTOR pathway.
ADP-ribose transferase PARP16 mediated-unfolded protein response contributes to neuronal cell damage in cerebral ischemia/reperfusion.
Antidepression of Xingpijieyu formula targets gut microbiota derived from depressive disorder.
Exosomes Derived from AT2R-Overexpressing BMSC Prevent Restenosis After Carotid Artery Injury by Attenuating the Injury-Induced Neointimal Hyperplasia.
Iso-seco-tanapartholide induces p62 covalent oligomerization to activate KEAP1-NRF2 redox pathway in rheumatoid arthritis.
Stevioside targets the NF-κB and MAPK pathways for inhibiting inflammation and apoptosis of chondrocytes and ameliorates osteoarthritis in vivo.
Matrix metalloproteinase-21 promotes metastasis via increasing the recruitment and M2 polarization of macrophages in HCC.
The upregulation of peripheral blood polyamine metabolites spermidine and spermine in children with hand, foot, mouth disease is related to enterovirus 71 capsid protein VP1, but not VP4.
Exosomal RBP4 potentiated hepatic lipid accumulation and inflammation in high-fat-diet-fed mice by promoting M1 polarization of Kupffer cells.
A cell-penetrating peptide exerts therapeutic effects against ischemic stroke by mediating the lysosomal degradation of sirtuin 5.
Identification of Clec7a as the therapeutic target of rTMS in alleviating Parkinson's disease: targeting neuroinflammation.
Salvianolic acid A alleviates heart failure with preserved ejection fraction via regulating TLR/Myd88/TRAF/NF-κB and p38MAPK/CREB signaling pathways.
Ginsenoside Rb1 protects hippocampal neurons in depressed rats based on mitophagy-regulated astrocytic pyroptosis.
MiR-146b-5p enriched bioinspired exosomes derived from fucoidan-directed induction mesenchymal stem cells protect chondrocytes in osteoarthritis by targeting TRAF6.
Neuron-Derived Exosomes Promote the Recovery of Spinal Cord Injury by Modulating Nerve Cells in the Cellular Microenvironment of the Lesion Area.
Mechanism of ligusticum cycloprolactam against neuroinflammation based on network pharmacology and experimental verification.
Inhibition of NF-κB Signaling-Mediated Crosstalk Between Macrophages and Preosteoblasts by Metformin Alleviates Trauma-Induced Heterotopic Ossification.
Structurally dynamic self-healable hydrogel cooperatively inhibits intestinal inflammation and promotes mucosal repair for enhanced ulcerative colitis treatment.
Profilin1 Regulates Trophoblast Invasion and Macrophage Differentiation.
ROS Scavenging Nanozyme Modulates Immunosuppression for Sensitized Cancer Immunotherapy.
Tumor-secreted GRP78 induces M2 polarization of macrophages by promoting lipid catabolism.
Role of omentin-1 in susceptibility to anxiety and depression like behaviors.
Electroacupuncture relieves chronic pain by promoting microglia M2 polarization in lumbar disc herniation rats.
TNFSF14/LIGHT promotes cardiac fibrosis and atrial fibrillation vulnerability via PI3Kγ/SGK1 pathway-dependent M2 macrophage polarisation.
PARP16-Mediated Stabilization of Amyloid Precursor Protein mRNA Exacerbates Alzheimer's Disease Pathogenesis.
Prenatally VPA exposure is likely to cause autistic-like behavior in the rats offspring via TREM2 down-regulation to affect the microglial activation and synapse alterations.
Activating α7nAChR helps post-myocardial infarction healing by regulating macrophage polarization via the STAT3 signaling pathway.
Hederagenin Suppresses Inflammation and Cartilage Degradation to Ameliorate the Progression of Osteoarthritis: An In vivo and In vitro Study.
Ioversol Induced Microglia Proinflammatory Activation and Oxidative Stress in Rats.
Abamectin causes toxicity to the carp respiratory system by triggering oxidative stress, inflammation, and apoptosis and inhibiting autophagy.
Lipid-accumulated reactive astrocytes promote disease progression in epilepsy.
Mechanisms regarding respiratory toxicity triggered by accumulation of ROS in carp exposed to difenoconazole.
Vagus nerve stimulation is a potential treatment for ischemic stroke.
Cardamonin alleviates chondrocytes inflammation and cartilage degradation of osteoarthritis by inhibiting ferroptosis via p53 pathway.
Autophagy-mediated circHIPK2 promotes lipopolysaccharide-induced astrocytic inflammation via SIGMAR1.
Analysis and verification of the circRNA regulatory network RNO_CIRCpedia_ 4214/RNO-miR-667-5p/Msr1 axis as a potential ceRNA promoting macrophage M2-like polarization in spinal cord injury.
Menstrual blood-derived endometrial stem cells alleviate neuroinflammation by modulating M1/M2 polarization in cell and rat Parkinson's disease models.
Regulatory Effects of Three-Dimensional Cultured Lipopolysaccharide-Pretreated Periodontal Ligament Stem Cell-Derived Secretome on Macrophages.
SGLT2i alleviates epicardial adipose tissue inflammation by modulating ketone body-glyceraldehyde-3-phosphate dehydrogenase malonylation pathway.
Functional OCT angiography reveals early retinal neurovascular dysfunction in diabetes with capillary resolution.
Collagen peptide promotes DSS-induced colitis by disturbing gut microbiota and regulation of macrophage polarization.
Iron Chelation Remits Memory Deficits Caused by the High-Fat Diet in a Mouse Model of Alzheimer's Disease.
Neferine Suppresses Experimental Colitis-Associated Colorectal Cancer by Inhibition of NF-[Formula: see text]B p65 and STAT3.
A Network Pharmacology Approach for Uncovering the Antitumor Effects and Potential Mechanisms of the Sijunzi Decoction for the Treatment of Gastric Cancer.
In Vitro Immunomodulatory Effects of Inonotus obliquus Extracts on Resting M0 Macrophages and LPS-Induced M1 Macrophages.
Astragali Radix-Coptis Rhizoma Herb Pair Attenuates Atherosclerosis in ApoE-/- Mice by Regulating the M1/M2 and Th1/Th2 Immune Balance and Activating the STAT6 Signaling Pathway.
Mechanical Stretch Promotes Macrophage Polarization and Inflammation via the RhoA-ROCK/NF-κB Pathway.
Macrophages with Different Polarization Phenotypes Influence Cementoblast Mineralization through Exosomes.
Grape Seed Proanthocyanidins Exert a Neuroprotective Effect by Regulating Microglial M1/M2 Polarisation in Rats with Spinal Cord Injury.
Corynoline Alleviates Osteoarthritis Development via the Nrf2/NF-κB Pathway.
Honokiol Ameliorates DSS-Induced Mouse Colitis by Inhibiting Inflammation and Oxidative Stress and Improving the Intestinal Barrier.
Supplementation with dietary omega-3 PUFA mitigates fetal brain inflammation and mitochondrial damage caused by high doses of sodium nitrite in maternal rats.
TREM2 improves neurological dysfunction and attenuates neuroinflammation, TLR signaling and neuronal apoptosis in the acute phase of intracerebral hemorrhage.
A construction and comprehensive analysis of the immune-related core ceRNA network and infiltrating immune cells in peripheral arterial occlusive disease.
Icariin protects vertebral endplate chondrocytes against apoptosis and degeneration via activating Nrf-2/HO-1 pathway.
Brevilin A Ameliorates Acute Lung Injury and Inflammation Through Inhibition of NF-κB Signaling via Targeting IKKα/β.
Characterization of Fatty Acid Metabolism-Related Genes Landscape for Predicting Prognosis and Aiding Immunotherapy in Glioma Patients.
The Protective Effect of Evodiamine in Osteoarthritis: An In Vitro and In Vivo Study in Mice Model.
Polydatin activates the Nrf2/HO-1 signaling pathway to protect cisplatin-induced hearing loss in guinea pigs.
Neutrophil Extracellular Traps Regulate HMGB1 Translocation and Kupffer Cell M1 Polarization During Acute Liver Transplantation Rejection.
Dehydrocostus Lactone Suppresses Dextran Sulfate Sodium-Induced Colitis by Targeting the IKKα/β-NF-κB and Keap1-Nrf2 Signalling Pathways.
Erratum: Addendum: A novel N-Arylpyridone compound alleviates the inflammatory and fibrotic reaction of silicosis by inhibiting the ASK1-p38 pathway and regulating macrophage polarization.
Network analysis and experimental pharmacology study explore the protective effects of Isoliquiritigenin on 5-fluorouracil-Induced intestinal mucositis.
Catalpol ameliorates CFA-induced inflammatory pain by targeting spinal cord and peripheral inflammation.
TGFBI secreted by tumor-associated macrophages promotes glioblastoma stem cell-driven tumor growth via integrin αvβ5-Src-Stat3 signaling.
Heparin binding epidermal growth factor-like growth factor is a prognostic marker correlated with levels of macrophages infiltrated in lung adenocarcinoma.
Scutellarin Protects Against Mitochondrial Reactive Oxygen Species-Dependent NLRP3 Inflammasome Activation to Attenuate Intervertebral Disc Degeneration.
Polyvinylpyrrolidone-Modified Taxifolin Liposomes Promote Liver Repair by Modulating Autophagy to Inhibit Activation of the TLR4/NF-κB Signaling Pathway.
A Composite Hydrogel Containing Mesoporous Silica Nanoparticles Loaded With Artemisia argyi Extract for Improving Chronic Wound Healing.
CXCR3 antagonist AMG487 ameliorates experimental autoimmune prostatitis by diminishing Th1 cell differentiation and inhibiting macrophage M1 phenotypic activation.
Serum-derived exosomes from SD rats induce inflammation in macrophages through the mTOR pathway.
Inhibition of Mer exacerbates early brain injury by regulating microglia/macrophage phenotype after subarachnoid hemorrhage in mice.
Vagus nerve stimulation promotes the M1-to-M2 transition via inhibition of TLR4/NF-κB in microglial to rescue the reperfusion injury.
Protective effects of budesonide on LPS-induced podocyte injury by modulating macrophage M1/M2 polarization: Evidence from in vitro and in silico studies.
Colchicine improves severe acute pancreatitis-induced acute lung injury by suppressing inflammation, apoptosis and oxidative stress in rats.
Tubuloside B, isolated from Cistanche tubulosa, a promising agent against M1 macrophage activation via synergistically targeting Mob1 and ERK1/2.
Magnoflorine attenuates inflammatory responses in RA by regulating the PI3K/Akt/NF-κB and Keap1-Nrf2/HO-1 signalling pathways in vivo and in vitro.
Omentin-1 promoted proliferation and ameliorated inflammation, apoptosis, and degeneration in human nucleus pulposus cells.
Therapeutic efficacy of human adipose mesenchymal stem cells in Crohn's colon fibrosis is improved by IFN-γ and kynurenic acid priming through indoleamine 2,3-dioxygenase-1 signaling.
Akebia Saponin D Inhibits the Inflammatory Reaction by Inhibiting the IL-6-STAT3-DNMT3b Axis and Activating the Nrf2 Pathway.
β2-Microglobulin Maintains Glioblastoma Stem Cells and Induces M2-like Polarization of Tumor-Associated Macrophages.
Flufenamic acid improves survival and neurologic outcome after successful cardiopulmonary resuscitation in mice.
Aucubin promoted neuron functional recovery by suppressing inflammation and neuronal apoptosis in a spinal cord injury model.
Chicoric acid attenuates tumor necrosis factor-α-induced inflammation and apoptosis via the Nrf2/HO-1, PI3K/AKT and NF-κB signaling pathways in C28/I2 cells and ameliorates the progression of osteoarthritis in a rat model.
Injectable and reactive oxygen species-scavenging gelatin hydrogel promotes neural repair in experimental traumatic brain injury.
PCSK9 promotes the progression and metastasis of colon cancer cells through regulation of EMT and PI3K/AKT signaling in tumor cells and phenotypic polarization of macrophages.
Astaxanthin attenuates osteoarthritis progression via inhibiting ferroptosis and regulating mitochondrial function in chondrocytes.
Difenoconazole disrupts the blood-brain barrier and results in neurotoxicity in carp by inhibiting the Nrf2 pathway mediated ROS accumulation.
OIT3 mediates macrophage polarization and facilitates hepatocellular carcinoma progression.
Caffeic acid phenethyl ester attenuates osteoarthritis progression by activating NRF2/HO‑1 and inhibiting the NF‑κB signaling pathway.
Vindoline ameliorates intestinal barrier damage in Crohn's disease mice through MAPK signaling pathway.
Macrophage targeted triptolide micelles capable of cGAS-STING pathway inhibition for rheumatoid arthritis treatment.
Biomimetic cell membrane-coated glucose/oxygen-exhausting nanoreactor for remodeling tumor microenvironment in targeted hypoxic tumor therapy.
N-acetylserotonin protects PC12 cells from hydrogen peroxide induced damage through ROS mediated PI3K / AKT pathway.
An increase in Semaphorin 3A biases the axonal direction and induces an aberrant dendritic arborization in an in vitro model of human neural progenitor differentiation.
Gut fungi enhances immunosuppressive function of myeloid-derived suppressor cells by activating PKM2-dependent glycolysis to promote colorectal tumorigenesis.
5-Methoxyflavone alleviates LPS-mediated lung injury by promoting Nrf2-mediated the suppression of NOX4/TLR4 axis in bronchial epithelial cells and M1 polarization in macrophages.
Carbon dots derived from folic acid attenuates osteoarthritis by protecting chondrocytes through NF-κB/MAPK pathway and reprogramming macrophages.
Amination Potentially Augments the Ameliorative Effect of Curcumin on Inhibition of the IL-6/Stat3/c-Myc Pathway and Gut Microbial Modulation in Colitis-Associated Tumorigenesis.
Orally Administered Ginkgolide C Attenuates DSS-Induced Colitis by Maintaining Gut Barrier Integrity, Inhibiting Inflammatory Responses, and Regulating Intestinal Flora.
Golgi Phosphoprotein 3 Mediates Radiation-Induced Bystander Effect via ERK/EGR1/TNF-α Signal Axis.
Antioxidant and Immunomodulatory Properties of Partially purified Exopolysaccharide from Lactobacillus Casei Isolated from Chinese Northeast Sauerkraut.
Inhalation of MSC-EVs is a noninvasive strategy for ameliorating acute lung injury.
Biomimetic Immunosuppressive Exosomes that Inhibit Cytokine Storms Contribute to the Alleviation of Sepsis.
Naringenin promoted spinal microglia M2 polarization in rat model of cancer-induced bone pain via regulating AMPK/PGC-1α signaling axis.
Enhanced immunogenicity of the tuberculosis subunit Rv0572c vaccine delivered in DMT liposome adjuvant as a BCG-booster.
Facile fabrication of a biocompatible composite gel with sustained release of aspirin for bone regeneration.
Growth differentiation factor 11 induces skeletal muscle atrophy via a STAT3-dependent mechanism in pulmonary arterial hypertension.
Targeted delivery of methotrexate by modified yeast β-glucan nanoparticles for rheumatoid arthritis therapy.
Hippocampal overexpression of TREM2 ameliorates high fat diet induced cognitive impairment and modulates phenotypic polarization of the microglia.
Inhibition of IRE1 suppresses the catabolic effect of IL-1β on nucleus pulposus cell and prevents intervertebral disc degeneration in vivo.
Neutrophil membrane-mimicking nanodecoys with intrinsic anti-inflammatory properties alleviate sepsis-induced acute liver injury and lethality in a mouse endotoxemia model.
Interleukin-10 genetically modified clinical-grade mesenchymal stromal cells markedly reinforced functional recovery after spinal cord injury via directing alternative activation of macrophages.
Icariin alleviates uveitis by targeting peroxiredoxin 3 to modulate retinal microglia M1/M2 phenotypic polarization.
Effects of ALA-PDT on the macrophages in wound healing and its related mechanisms in vivo and in vitro.
Methionine strengthens anti-inflammation of rice protein via depressing NF-κB activation and stimulating Msr expression in rats fed cholesterol-enriched diets.
Farrerol alleviates collagenase-induced tendinopathy by inhibiting ferroptosis in rats.
Transposon-mediated glial cell line-derived neurotrophic factor overexpression in human adipose tissue-derived mesenchymal stromal cells: A potential approach for neuroregenerative medicine?
Robust drug bioavailability and safety for rheumatoid arthritis therapy using D-amino acids-based supramolecular hydrogels.
MicroRNA-200c-5p targets NIMA Related Kinase 7 (NEK7) to inhibit NOD-like receptor 3 (NLRP3) inflammasome activation, MODE-K cell pyroptosis, and inflammatory bowel disease in mice.
The circadian clock protein Rev-erbα provides neuroprotection and attenuates neuroinflammation against Parkinson's disease via the microglial NLRP3 inflammasome.
DKK3 ameliorates neuropathic pain via inhibiting ASK-1/JNK/p-38-mediated microglia polarization and neuroinflammation.
Rutin Inhibits Ox-LDL-Mediated Macrophage Inflammation and Foam Cell Formation by Inducing Autophagy and Modulating PI3K/ATK Signaling.
Implantation of a nerve protector embedded with human GMSC-derived Schwann-like cells accelerates regeneration of crush-injured rat sciatic nerves.
Progranulin deficiency promotes persistent neuroinflammation and causes regional pathology in the hippocampus following traumatic brain injury.
Construction and comprehensive analysis of a lncRNA-mRNA interactive network to reveal a potential lncRNA for hepatic encephalopathy development.
Epigallocatechin-3-O-gallate ameliorates oxidative stress-induced chondrocyte dysfunction and exerts chondroprotective effects via the Keap1/Nrf2/ARE signaling pathway.
Melatonin ameliorates Parkinson's disease via regulating microglia polarization in a RORα-dependent pathway.
Extracellular vesicle miR-32 derived from macrophage promotes arterial calcification in mice with type 2 diabetes via inhibiting VSMC autophagy.
Wharton's jelly mesenchymal stem cell-derived small extracellular vesicles as natural nanoparticles to attenuate cartilage injury via microRNA regulation.
SENP6 induces microglial polarization and neuroinflammation through de-SUMOylation of Annexin-A1 after cerebral ischaemia-reperfusion injury.
Adenosine kinase (ADK) inhibition with ABT-702 induces ADK protein degradation and a distinct form of sustained cardioprotection.
Beneficial effects of QTC-4-MeOBnE in an LPS-induced mouse model of depression and cognitive impairments: The role of blood-brain barrier permeability, NF-κB signaling, and microglial activation.
Resveratrol Improves Synaptic Plasticity in Hypoxic-Ischemic Brain Injury in Neonatal Mice via Alleviating SIRT1/NF-κB Signaling-Mediated Neuroinflammation.
Maresin 1 protects against lipopolysaccharide/d-galactosamine-induced acute liver injury by inhibiting macrophage pyroptosis and inflammatory response.
Wilforlide A ameliorates the progression of rheumatoid arthritis by inhibiting M1 macrophage polarization.
Injectable hyaluronic acid hydrogel loaded with BMSC and NGF for traumatic brain injury treatment.
Extracellular vesicle-mediated delivery of circDYM alleviates CUS-induced depressive-like behaviours.
Artesunate attenuates atherosclerosis by inhibiting macrophage M1-like polarization and improving metabolism.
The ethanol extract of flower buds of Tussilago farfara L. attenuates cigarette smoke-induced lung inflammation through regulating NLRP3 inflammasome, Nrf2, and NF-κB.
Inhibition of Noncanonical Ca(2+) Oscillation/Calcineurin/GSK-3β Pathway Contributes to Anti-Inflammatory Effect of Sigma-1 Receptor Activation.
Enhancement of anti-inflammatory effect of cattle bile by fermentation and its inhibition of neuroinflammation on microglia by inhibiting NLRP3 inflammasome.
One-Step Synthesis of Multifunctional Chitosan Hydrogel for Full-Thickness Wound Closure and Healing.
Gut microbiota-derived butyrate regulates gut mucus barrier repair by activating the macrophage/WNT/ERK signaling pathway.
Transcutaneous delivery of mung bean-derived nanoparticles for amelioration of psoriasis-like skin inflammation.
METTL3 overexpression aggravates LPS-induced cellular inflammation in mouse intestinal epithelial cells and DSS-induced IBD in mice.
Sphingosine-1 phosphate receptor 1 contributes to central sensitization in recurrent nitroglycerin-induced chronic migraine model.
Immune-responsive gene 1/itaconate activates nuclear factor erythroid 2-related factor 2 in microglia to protect against spinal cord injury in mice.
Caffeine treatment started before injury reduces hypoxic-ischemic white-matter damage in neonatal rats by regulating phenotypic microglia polarization.
Indoleamine 2,3-dioxygenase mediates the therapeutic effects of adipose-derived stromal/stem cells in experimental periodontitis by modulating macrophages through the kynurenine-AhR-NRF2 pathway.
Catalpol relieved angiotensin II-induced blood-brain barrier destruction via inhibiting the TLR4 pathway in brain endothelial cells.
Shenlian extract attenuates myocardial ischaemia-reperfusion injury via inhibiting M1 macrophage polarization by silencing miR-155.
Exosome modification to better alleviates endoplasmic reticulum stress induced chondrocyte apoptosis and osteoarthritis.
L-Methionine inhibits 4-hydroxy-2-nonenal accumulation and suppresses inflammation in growing rats.
Pexidartinib (PLX3397) through restoring hippocampal synaptic plasticity ameliorates social isolation-induced mood disorders.
Freshwater Clam Extract Attenuates Indomethacin-Induced Gastric Damage In Vitro and In Vivo.
Anti-Amnesic Effect of Synbiotic Supplementation Containing Corni fructus and Limosilactobacillus reuteri in DSS-Induced Colitis Mice.
Astragaloside IV attenuates IL-1β-induced intervertebral disc degeneration through inhibition of the NF-κB pathway.
Betaine supplementation alleviates dextran sulfate sodium-induced colitis via regulating the inflammatory response, enhancing the intestinal barrier, and altering gut microbiota.
Augmented PFKFB3-mediated glycolysis by interferon-γ promotes inflammatory M1 polarization through the JAK2/STAT1 pathway in local vascular inflammation in Takayasu arteritis.
Aloe polymeric acemannan inhibits the cytokine storm in mouse pneumonia models by modulating macrophage metabolism.
Macrophage depletion blocks congenital SARM1-dependent neuropathy.
Upregulation of RCAN1.4 by HIF1α alleviates OGD-induced inflammatory response in astrocytes.
Cornuside Is a Potential Agent against Alzheimer's Disease via Orchestration of Reactive Astrocytes.
DNA Origami as a Nanomedicine for Targeted Rheumatoid Arthritis Therapy through Reactive Oxygen Species and Nitric Oxide Scavenging.
Capsaicin ameliorates inflammation in a TRPV1-independent mechanism by inhibiting PKM2-LDHA-mediated Warburg effect in sepsis.
Phenolic Acids from Fructus Chebulae Immaturus Alleviate Intestinal Ischemia-Reperfusion Injury in Mice through the PPARα/NF-κB Pathway.
Rice protein suppresses 4-hydroxy-2-nonenal-induced inflammation owing to methionine availability.
Resolution of inflammation is disturbed in acute ischemic stroke with diabetes mellitus and rescued by resolvin D2 treatment.
San-Wu-Huang-Qin decoction attenuates tumorigenesis and mucosal barrier impairment in the AOM/DSS model by targeting gut microbiome.
Tangeretin suppresses osteoarthritis progression via the Nrf2/NF-κB and MAPK/NF-κB signaling pathways.
Amelioration of Neuropathic Pain and Attenuation of Neuroinflammation Responses by Tetrahydropalmatine Through the p38MAPK/NF-κB/iNOS Signaling Pathways in Animal and Cellular Models.
Lipoxin A4 regulates M1/M2 macrophage polarization via FPR2-IRF pathway.
Itaconate attenuates osteoarthritis by inhibiting STING/NF-κB axis in chondrocytes and promoting M2 polarization in macrophages.
Undescribed ecdysteroids and phenolic glycosides from the roots of Cyathula officinalis Kuan and their anti-inflammatory activity in LPS-induced RAW 264.7 macrophages in vitro.
Ellagic acid attenuates interleukin-1β-induced oxidative stress and exerts protective effects on chondrocytes through the Kelch-like ECH-associated protein 1 (Keap1)/ Nuclear factor erythroid 2-related factor 2 (Nrf2) pathway.
High proportion strontium-doped micro-arc oxidation coatings enhance early osseointegration of titanium in osteoporosis by anti-oxidative stress pathway.
MicroRNA-146a-5p-modified human umbilical cord mesenchymal stem cells enhance protection against diabetic nephropathy in rats through facilitating M2 macrophage polarization.
Inhibition of Notch activity suppresses hyperglycemia-augmented polarization of macrophages to the M1 phenotype and alleviates acute pancreatitis.
Urolithin A promotes mitophagy and suppresses NLRP3 inflammasome activation in lipopolysaccharide-induced BV2 microglial cells and MPTP-induced Parkinson's disease model.
lncRNA Gm16410 Mediates PM(2).(5)-Induced Macrophage Activation via PI3K/AKT Pathway.
Characterization of an Aging-Based Diagnostic Gene Signature and Molecular Subtypes With Diverse Immune Infiltrations in Atherosclerosis.
Inhibition of Sphingosine-1-Phosphate Receptor 2 Prevents Thoracic Aortic Dissection and Rupture.
Gut Immunity and Microbiota Dysbiosis Are Associated with Altered Bile Acid Metabolism in LPS-Challenged Piglets.
Deficiency of IKKα in Macrophages Mitigates Fibrosis Progression in the Kidney after Renal Ischemia-Reperfusion Injury.
TNF-Like Ligand 1 Aberrance Aggravates Nonalcoholic Steatohepatitis via M1 Macrophage Polarization.
Retinal Neuropathy in IGT Stage of OLETF Rats: Another Characteristic Change of Diabetic Retinopathy.
ALDH2/SIRT1 Contributes to Type 1 and Type 2 Diabetes-Induced Retinopathy through Depressing Oxidative Stress.
Albumin-encapsulated Nanoparticles of Naproxen Platinum(IV) Complexes with Inflammation Inhibitory Competence Displaying Effective Antitumor Activities in vitro and in vivo.
Rosuvastatin Nanomicelles Target Neuroinflammation and Improve Neurological Deficit in a Mouse Model of Intracerebral Hemorrhage.
GDC-0575, a CHK1 Inhibitor, Impairs the Development of Colitis and Colitis-Associated Cancer by Inhibiting CCR2(+) Macrophage Infiltration in Mice.
Upregulation of Neuronal Cylindromatosis Expression is Essential for Electroacupuncture-Mediated Alleviation of Neuroinflammatory Injury by Regulating Microglial Polarization in Rats Subjected to Focal Cerebral Ischemia/Reperfusion.
Irradiation-Induced Activated Microglia Affect Brain Metastatic Colonization of NSCLC Cells via miR-9/CDH1 Axis.
Histone Deacetylase 6 Regulates the Activation of M1 Macrophages by the Glycolytic Pathway During Acute Liver Failure.
Mesenchymal Stem Cells Overexpressing ACE2 Favorably Ameliorate LPS-Induced Inflammatory Injury in Mammary Epithelial Cells.
Activation of α7nAChR Protects Against Gastric Inflammation and Dysmotility in Parkinson's Disease Rats.
Berberine Improves Irinotecan-Induced Intestinal Mucositis Without Impairing the Anti-colorectal Cancer Efficacy of Irinotecan by Inhibiting Bacterial β-glucuronidase.
Construction and Analysis of Immune Infiltration-Related ceRNA Network for Kidney Stones.
Claudin-5 Affects Endothelial Autophagy in Response to Early Hypoxia.
Resveratrol Alleviates Levodopa-Induced Dyskinesia in Rats.
Ligustrazine Alleviate Acute Lung Injury Through Suppressing Pyroptosis and Apoptosis of Alveolar Macrophages.
Antioxidant activity of mesenchymal stem cell-derived extracellular vesicles restores hippocampal neurons following seizure damage.
Pseudomonas aeruginosa PcrV Enhances the Nitric Oxide-Mediated Tumoricidal Activity of Tumor-Associated Macrophages via a TLR4/PI3K/AKT/mTOR-Glycolysis-Nitric Oxide Circuit.
Colon-Targeted Adhesive Hydrogel Microsphere for Regulation of Gut Immunity and Flora.
The spatial form periosteal-bone complex promotes bone regeneration by coordinating macrophage polarization and osteogenic-angiogenic events.
Injectable shear-thinning polylysine hydrogels for localized immunotherapy of gastric cancer through repolarization of tumor-associated macrophages.
Chemical structure and anti-inflammatory activity of a branched polysaccharide isolated from Phellinus baumii.
Regulatory T cells protect against brain damage by alleviating inflammatory response in neuromyelitis optica spectrum disorder.
Formosanin C attenuates lipopolysaccharide-induced inflammation through nuclear factor-κB inhibition in macrophages.
CLEC5A knockdown protects against cardiac dysfunction after myocardial infarction by suppressing macrophage polarization, NLRP3 inflammasome activation, and pyroptosis.
Ameliorative effects of miR-423-5p against polarization of microglial cells of the M1 phenotype by targeting a NLRP3 inflammasome signaling pathway.
Avicularin suppresses cartilage extracellular matrix degradation and inflammation via TRAF6/MAPK activation.
Carbon Monoxide-Releasing Molecule-3 Regulates the Polarization of Lipopolysaccharide-Induced Macrophages.
Pharmacological Activation of RXR-α Promotes Hematoma Absorption via a PPAR-γ-dependent Pathway After Intracerebral Hemorrhage.
PARP14 inhibits microglial activation via LPAR5 to promote post-stroke functional recovery.
Rapid and effective treatment of traumatic spinal cord injury using stem cell derived exosomes.
Isoliquiritigenin alleviates LPS/ D-GalN-induced acute liver failure by activating the PGC-1α/ Nrf2 pathway to reduce oxidative stress and inflammatory response.
Glial cell line-derived neurotrophic factor ameliorates dextran sulfate sodium-induced colitis in mice via a macrophage-mediated pathway.
Discovery of Phenolic Glycoside from Hyssopus cuspidatus Attenuates LPS-Induced Inflammatory Responses by Inhibition of iNOS and COX-2 Expression through Suppression of NF-κB Activation.
Vagus nerve stimulation mediates microglia M1/2 polarization via inhibition of TLR4 pathway after ischemic stroke.
Photobiomodulation inhibits the activation of neurotoxic microglia and astrocytes by inhibiting Lcn2/JAK2-STAT3 crosstalk after spinal cord injury in male rats.
Sesquiterpene Lactones from Sigesbeckia glabrescens Possessing Potent Anti-inflammatory Activity by Directly Binding to IKKα/β.
The Protective Role of Yin-Yang 1 in Cardiac Injury and Remodeling After Myocardial Infarction.
Decreased nitric oxide content mediated by asymmetrical dimethylarginine and protein l-arginine methyltransferase 3 in macrophages induces trophoblast apoptosis: a potential cause of recurrent miscarriage.
Tetramethylpyrazine Protects Blood-Spinal Cord Barrier Integrity by Modulating Microglia Polarization Through Activation of STAT3/SOCS3 and Inhibition of NF-кB Signaling Pathways in Experimental Autoimmune Encephalomyelitis Mice.
Lipoxin A4 regulates microglial M1/M2 polarization after cerebral ischemia-reperfusion injury via the Notch signaling pathway.
Protective effect of recombinant Lactobacillus plantarum against H(2)O(2)-induced oxidative stress in HUVEC cells.
Cardamonin protects nucleus pulposus cells against IL-1β-induced inflammation and catabolism via Nrf2/NF-κB axis.
CSF1/CSF1R-mediated Crosstalk Between Choroidal Vascular Endothelial Cells and Macrophages Promotes Choroidal Neovascularization.
Loganin alleviates sepsis-induced acute lung injury by regulating macrophage polarization and inhibiting NLRP3 inflammasome activation.
IL-1β pre-stimulation enhances the therapeutic effects of endometrial regenerative cells on experimental colitis.
Dietary Ursolic Acid Prevents Alcohol-Induced Liver Injury via Gut-Liver Axis Homeostasis Modulation: The Key Role of Microbiome Manipulation.
Thymosin β4 reverses phenotypic polarization of glial cells and cognitive impairment via negative regulation of NF-κB signaling axis in APP/PS1 mice.
X-ray Structure-Guided Discovery of a Potent, Orally Bioavailable, Dual Human Indoleamine/Tryptophan 2,3-Dioxygenase (hIDO/hTDO) Inhibitor That Shows Activity in a Mouse Model of Parkinson's Disease.
Protective effect of scorpion venom heat-resistant synthetic peptide against PM(2.5)-induced microglial polarization via TLR4-mediated autophagy activating PI3K/AKT/NF-κB signaling pathway.
A systematic CRISPR screen reveals an IL-20/IL20RA-mediated immune crosstalk to prevent the ovarian cancer metastasis.
Wireless Localized Electrical Stimulation Generated by an Ultrasound-Driven Piezoelectric Discharge Regulates Proinflammatory Macrophage Polarization.
Effects of medicine food Fructus Gardeniae on liver and kidney functions after oral administration to rats for 12 weeks.
α-Cyperone (CYP) down-regulates NF-κB and MAPKs signaling, attenuating inflammation and extracellular matrix degradation in chondrocytes, to ameliorate osteoarthritis in mice.
Anti-inflammatory and tight junction protective activity of the herbal preparation STW 5-II on mouse intestinal organoids.
Impaired autophagy in microglia aggravates dopaminergic neurodegeneration by regulating NLRP3 inflammasome activation in experimental models of Parkinson's disease.
Physcion 8-O-β-glucopyranoside ameliorates liver fibrosis through inflammation inhibition by regulating SIRT3-mediated NF-κB P65 nuclear expression.
Echinacea polysaccharide attenuates lipopolysaccharide‑induced acute kidney injury via inhibiting inflammation, oxidative stress and the MAPK signaling pathway.
Myricetin ameliorates sepsis-associated acute lung injury in a murine sepsis model.
Sodium alginate/collagen hydrogel loaded with human umbilical cord mesenchymal stem cells promotes wound healing and skin remodeling.
Rea regulates microglial polarization and attenuates neuronal apoptosis via inhibition of the NF-κB and MAPK signalings for spinal cord injury repair.
Critical roles of sphingosine kinase 1 in the regulation of neuroinflammation and neuronal injury after spinal cord injury.
Phosphorylated nuclear factor erythroid 2-related factor 2 promotes the secretion of C-C motif chemokine ligand 2 and the recruitment of M2 macrophages.
Schizandrin A ameliorates cognitive functions via modulating microglial polarisation in Alzheimer's disease mice.
CircPrkcsh, a circular RNA, contributes to the polarization of microglia towards the M1 phenotype induced by spinal cord injury and acts via the JNK/p38 MAPK pathway.
PLXNA2 knockdown promotes M2 microglia polarization through mTOR/STAT3 signaling to improve functional recovery in rats after cerebral ischemia/reperfusion injury.
Diterpenoid alkaloids from Delphinium forrestii var. viride and their anti-inflammation activity.
The glycolysis inhibitor 2-deoxyglucose ameliorates adjuvant-induced arthritis by regulating macrophage polarization in an AMPK-dependent manner.
Inhibition of Dectin-1 Ameliorates Neuroinflammation by Regulating Microglia/Macrophage Phenotype After Intracerebral Hemorrhage in Mice.
Acetylcholinesterase inhibition with Pyridostigmine attenuates hypertension and neuroinflammation in the paraventricular nucleus in rat model for Preeclampsia.
The Promising Role of Chitosan-Poloxamer 188 Nanocrystals in Improving Diosmin Dissolution and Therapeutic Efficacy against Ferrous Sulfate-Induced Hepatic Injury in Rats.
Probiotic Bacillus cereus Alleviates Dextran Sulfate Sodium-Induced Colitis in Mice through Improvement of the Intestinal Barrier Function, Anti-Inflammation, and Gut Microbiota Modulation.
Synergistic anti-inflammatory activity of apigenin and curcumin co-encapsulated in caseins assessed with lipopolysaccharide-stimulated RAW 264.7 macrophages.
FNDC5 induces M2 macrophage polarization and promotes hepatocellular carcinoma cell growth by affecting the PPARγ/NF-κB/NLRP3 pathway.
MicroRNA-155-5p promotes neuroinflammation and central sensitization via inhibiting SIRT1 in a nitroglycerin-induced chronic migraine mouse model.
The role of adenosine A(1) receptor in the peripheral tramadol's effect in the temporomandibular joint of rats.
The expression profile and bioinformatics analysis of microRNAs in human bronchial epithelial cells treated by beryllium sulfate.
Aiduqing formula inhibits breast cancer metastasis by suppressing TAM/CXCL1-induced Treg differentiation and infiltration.
Nitric oxide mediates disruption of human placental trophoblast invasion induced by perfluorobutane sulfonate.
SCARF1 promotes M2 polarization of Kupffer cells via calcium-dependent PI3K-AKT-STAT3 signalling to improve liver transplantation.
Morroniside protects OLN-93 cells against H(2)O(2)-induced injury through the PI3K/Akt pathway-mediated antioxidative stress and antiapoptotic activities.
Targeting macrophage liver X receptors by hydrogel-encapsulated T0901317 reduces atherosclerosis without effect on hepatic lipogenesis.
Angiotensin II type 1 receptor is involved in flow-induced vasomotor responses of isolated middle cerebral arteries: role of oxidative stress.
Deliver Anti-inflammatory Drug Baicalein to Macrophages by Using a Crystallization Strategy.
Injectable Gelatin Hydrogel Suppresses Inflammation and Enhances Functional Recovery in a Mouse Model of Intracerebral Hemorrhage.
Koumine Alleviates Lipopolysaccharide-Induced Intestinal Barrier Dysfunction in IPEC-J2 Cells by Regulating Nrf2/NF-κB Pathway.
Ovariectomy Induces Microglial Cell Activation and Inflammatory Response in Rat Prefrontal Cortices to Accelerate the Chronic Unpredictable Stress-Mediated Anxiety and Depression.
Emodin Alleviates Hydrogen Peroxide-Induced Inflammation and Oxidative Stress via Mitochondrial Dysfunction by Inhibiting the PI3K/mTOR/GSK3β Pathway in Neuroblastoma SH-SY5Y Cells.
Intranasal Delivery of Bone Marrow Stromal Cells Preconditioned with Fasudil to Treat a Mouse Model of Parkinson's Disease.
La(2)O(3) Nanoparticles Induce Reproductive Toxicity Mediated by the Nrf-2/ARE Signaling Pathway in Kunming Mice.
Hypothermia-Induced Ubiquitination of Voltage-Dependent Anion Channel 3 Protects BV2 Microglia Cells From Cytotoxicity Following Oxygen-Glucose Deprivation/Recovery.
Salvianolic Acid A Has Anti-Osteoarthritis Effect In Vitro and In Vivo.
Tetramethylpyrazine Ameliorates Lipopolysaccharide-Induced Sepsis in Rats via Protecting Blood-Brain Barrier, Impairing Inflammation and Nitrous Oxide Systems.
CCR4 Antagonist (C021) Administration Diminishes Hypersensitivity and Enhances the Analgesic Potency of Morphine and Buprenorphine in a Mouse Model of Neuropathic Pain.
Formononetin attenuates atherosclerosis via regulating interaction between KLF4 and SRA in apoE(-/-) mice.
Bifunctional supramolecular nanofiber inhibits atherosclerosis by enhancing plaque stability and anti-inflammation in apoE(-/-) mice.
Mesenchymal stem cell-loaded thermosensitive hydroxypropyl chitin hydrogel combined with a three-dimensional-printed poly(ε-caprolactone) /nano-hydroxyapatite scaffold to repair bone defects via osteogenesis, angiogenesis and immunomodulation.
Herb-sourced emodin inhibits angiogenesis of breast cancer by targeting VEGFA transcription.
Geraniol-mediated osteoarthritis improvement by down-regulating PI3K/Akt/NF-κB and MAPK signals: In vivo and in vitro studies.
Fucoidan inhibits tooth movement by promoting restorative macrophage polarization through the STAT3 pathway.
Inhibition of miR-181a-5p reduces astrocyte and microglia activation and oxidative stress by activating SIRT1 in immature rats with epilepsy.
MG53 Protects hUC-MSCs against Inflammatory Damage and Synergistically Enhances Their Efficacy in Neuroinflammation Injured Brain through Inhibiting NLRP3/Caspase-1/IL-1β Axis.
Arachidonic Acid Metabolites of CYP450 Enzymes and HIF-1α Modulate Endothelium-Dependent Vasorelaxation in Sprague-Dawley Rats under Acute and Intermittent Hyperbaric Oxygenation.
Peripheral soluble epoxide hydrolase inhibition reduces hypernociception and inflammation in albumin-induced arthritis in temporomandibular joint of rats.
Anti-arthritis effect of berberine associated with regulating energy metabolism of macrophages through AMPK/ HIF-1α pathway.
Increased expression levels of inflammatory cytokines and adhesion molecules in lipopolysaccharide‑induced acute inflammatory apoM‑/‑ mice.
Protective effect of astaxanthin against La(2)O(3) nanoparticles induced neurotoxicity by activating PI3K/AKT/Nrf-2 signaling in mice.
(-)-Hydroxycitric Acid Alleviates Oleic Acid-Induced Steatosis, Oxidative Stress, and Inflammation in Primary Chicken Hepatocytes by Regulating AMP-Activated Protein Kinase-Mediated Reactive Oxygen Species Levels.
Ketogenic Diet Elicits Antitumor Properties through Inducing Oxidative Stress, Inhibiting MMP-9 Expression, and Rebalancing M1/M2 Tumor-Associated Macrophage Phenotype in a Mouse Model of Colon Cancer.
Distribution and polarization of microglia and macrophages at injured sites and the lumbar enlargement after spinal cord injury.
Protective effect of astaxanthin against SnS(2) nanoflowers induced testes toxicity by suppressing RIPK1-RIPK3-MLKL signaling in mice.
Scoparone improves hepatic inflammation and autophagy in mice with nonalcoholic steatohepatitis by regulating the ROS/P38/Nrf2 axis and PI3K/AKT/mTOR pathway in macrophages.
Honokiol inhibits carotid artery atherosclerotic plaque formation by suppressing inflammation and oxidative stress.
Stimulator of IFN genes mediates neuroinflammatory injury by suppressing AMPK signal in experimental subarachnoid hemorrhage.
Oroxylin A inhibits carcinogen-induced skin tumorigenesis through inhibition of inflammation by regulating SHCBP1 in mice.
A Comparison of Splenic Pathologic Change and Immune Function in HBV-Related Portal Hypertension and Chinese Budd-Chiari Syndrome Patients with Hypersplenism.
XIAOPI formula inhibits the pre-metastatic niche formation in breast cancer via suppressing TAMs/CXCL1 signaling.
The protective effect of hesperetin in osteoarthritis: an in vitro and in vivo study.
TNF-α/HMGB1 inflammation signalling pathway regulates pyroptosis during liver failure and acute kidney injury.
AGK2 Alleviates Lipopolysaccharide Induced Neuroinflammation through Regulation of Mitogen-Activated Protein Kinase Phosphatase-1.
Beneficial Effects of Theta-Burst Transcranial Magnetic Stimulation on Stroke Injury via Improving Neuronal Microenvironment and Mitochondrial Integrity.
lncRNA PVT1 Promotes Tumorigenesis of Colorectal Cancer by Stabilizing miR-16-5p and Interacting with the VEGFA/VEGFR1/AKT Axis.
TSPO ligand Ro5-4864 modulates microglia/macrophages polarization after subarachnoid hemorrhage in mice.
Activation of PPAR-γ induces macrophage polarization and reduces neutrophil migration mediated by heme oxygenase 1.
The protective effect of myricitrin in osteoarthritis: An in vitro and in vivo study.
10-Hydroxydecanoic acid inhibits LPS-induced inflammation by targeting p53 in microglial cells.
Mechanism investigation on Bisphenol S-induced oxidative stress and inflammation in murine RAW264.7 cells: The role of NLRP3 inflammasome, TLR4, Nrf2 and MAPK.
Karyopherin α 2 promotes proliferation, migration and invasion through activating NF-κB/p65 signaling pathways in melanoma cells.
Chicken thalamic injury induced by copper (II) or / and arsenite exposure involves oxidative stress and inflammation-induced apoptosis.
Antidepressant activity of ω-3 polyunsaturated fatty acids in ovariectomized rats: role of neuroinflammation and microglial polarization.
TLR 7/8 agonist reverses oxaliplatin resistance in colorectal cancer via directing the myeloid-derived suppressor cells to tumoricidal M1-macrophages.
Biglycan regulates neuroinflammation by promoting M1 microglial activation in early brain injury after experimental subarachnoid hemorrhage.
MiRNA-192-5p attenuates airway remodeling and autophagy in asthma by targeting MMP-16 and ATG7.
Silencing of PTX3 alleviates LPS-induced inflammatory pain by regulating TLR4/NF-κB signaling pathway in mice.
CT/NIRF dual-modal imaging tracking and therapeutic efficacy of transplanted mesenchymal stem cells labeled with Au nanoparticles in silica-induced pulmonary fibrosis.
Syringin protects against colitis by ameliorating inflammation.
Intravenously Infusing the Secretome of Adipose-Derived Mesenchymal Stem Cells Ameliorates Neuroinflammation and Neurological Functioning After Traumatic Brain Injury.
Maresin 1 mitigates concanavalin A-induced acute liver injury in mice by inhibiting ROS-mediated activation of NF-κB signaling.
Autotaxin stimulates LPA2 receptor in macrophages and exacerbates dextran sulfate sodium-induced acute colitis.
Protective effect of hydroxysafflor yellow A on dopaminergic neurons against 6-hydroxydopamine, activating anti-apoptotic and anti-neuroinflammatory pathways.
Loganin inhibits macrophage M1 polarization and modulates sirt1/NF-κB signaling pathway to attenuate ulcerative colitis.
Akebia Saponin D suppresses inflammation in chondrocytes via the NRF2/HO-1/NF-κB axis and ameliorates osteoarthritis in mice.
Glycitin Suppresses Cartilage Destruction of Osteoarthritis in Mice.
Bone marrow mesenchymal stem cells combine with normothermic machine perfusion to improve rat donor liver quality-the important role of hepatic microcirculation in donation after circulatory death.
Advanced glycation end products enhance macrophage polarization to the M1 phenotype via the HIF-1α/PDK4 pathway.
S-allylmercaptocysteine ameliorates lipopolysaccharide-induced acute lung injury in mice by inhibiting inflammation and oxidative stress via nuclear factor kappa B and Keap1/Nrf2 pathways.
4β-Hydroxywithanolide E from Goldenberry (Whole Fruits of Physalis peruviana L.) as a Promising Agent against Chronic Obstructive Pulmonary Disease.
Silica particles disorganize the polarization of pulmonary macrophages in mice.
Exosome-encapsulated miRNAs contribute to CXCL12/CXCR4-induced liver metastasis of colorectal cancer by enhancing M2 polarization of macrophages.
Role of Antioxidants in the Protection from Aging-Related Diseases.
1-Trichloromethyl-1,2,3,4-tetrahydro-beta-carboline (TaClo) Induces the Apoptosis of Dopaminergic Neurons via Oxidative Stress and Neuroinflammation.
Relationship of Inflammatory Cytokines From M1-Type Microglia/Macrophages at the Injured Site and Lumbar Enlargement With Neuropathic Pain After Spinal Cord Injury in the CCL21 Knockout (plt) Mouse.
Nobiletin Inhibits IL-1β-Induced Inflammation in Chondrocytes via Suppression of NF-κB Signaling and Attenuates Osteoarthritis in Mice.
Myeloid-Derived Suppressor Cells and γδT17 Cells Contribute to the Development of Gastric MALT Lymphoma in H. felis-Infected Mice.
Fusobacterium nucleatum Aggravates the Progression of Colitis by Regulating M1 Macrophage Polarization via AKT2 Pathway.
Adenovirus‑mediated overexpression of bone morphogenetic protein‑9 promotes methionine choline deficiency‑induced non‑alcoholic steatohepatitis in non‑obese mice.
Mechanism Underlying the Protective Effect of Selenium on NO-Induced Oxidative Damage in Bovine Mammary Epithelial Cells.
An herbal-compound-based combination therapy that relieves cirrhotic ascites by affecting the L-arginine/nitric oxide pathway: A metabolomics-based systematic study.
Sinomenine contributes to the inhibition of the inflammatory response and the improvement of osteoarthritis in mouse-cartilage cells by acting on the Nrf2/HO-1 and NF-κB signaling pathways.
Chrysophanol attenuates airway inflammation and remodeling through nuclear factor-kappa B signaling pathway in asthma.
Therapeutic effect of yttrium oxide nanoparticles for the treatment of fulminant hepatic failure.
Dehydroepiandrosterone alleviates E. Coli O157:H7-induced inflammation by preventing the activation of p38 MAPK and NF-κB pathways in mice peritoneal macrophages.
γ-Oryzanol alleviates acetaminophen-induced liver injury: roles of modulating AMPK/GSK3β/Nrf2 and NF-κB signaling pathways.
Keel Fracture Causes Stress and Inflammatory Responses and Inhibits the Expression of the Orexin System in Laying Hens.
Neuroprotection of Andrographolide Against Microglia-Mediated Inflammatory Injury and Oxidative Damage in PC12 Neurons.
Conditional Controlled Light/Dark Cycle Influences Exercise-Induced Benefits in a Rat Model with Osteoarthritis: In Vitro and In Vivo Study.
miR-let-7a suppresses α-Synuclein-induced microglia inflammation through targeting STAT3 in Parkinson's disease.
Chondrocyte apoptosis in rat mandibular condyles induced by dental occlusion due to mitochondrial damage caused by nitric oxide.
High Molecular Weight Hyaluronan Suppresses Macrophage M1 Polarization and Enhances IL-10 Production in PM(2.5)-Induced Lung Inflammation.
Cortistatin binds to TNF-α receptors and protects against osteoarthritis.
Sweroside Alleviated LPS-Induced Inflammation via SIRT1 Mediating NF-κB and FOXO1 Signaling Pathways in RAW264.7 Cells.
In Vitro and In Vivo Anti-Inflammatory Effects of Polyphyllin VII through Downregulating MAPK and NF-κB Pathways.
Effect of dexmedetomidine on kidney injury in sepsis rats through TLR4/MyD88/NF-κB/iNOS signaling pathway.
Berberine attenuates arthritis in adjuvant-induced arthritic rats associated with regulating polarization of macrophages through AMPK/NF-кB pathway.
Tempol alleviates chronic intermittent hypoxia-induced pancreatic injury through repressing inflammation and apoptosis.
Analgesic and anti-inflammatory effects and molecular mechanisms of Kadsura heteroclita stems, an anti-arthritic Chinese Tujia ethnomedicinal herb.
BG-4 from Bitter Gourd (Momordica charantia) Differentially Affects Inflammation In Vitro and In Vivo.
Synthesis of andrographolide analogues and their neuroprotection and neurite outgrowth-promoting activities.
Aspirin inhibits inflammation and scar formation in the injury tendon healing through regulating JNK/STAT-3 signalling pathway.
Involvement of NLRP3 inflammasome in methamphetamine-induced microglial activation through miR-143/PUMA axis.
Ghrelin protects against contact dermatitis and psoriasiform skin inflammation by antagonizing TNF-α/NF-κB signaling pathways.
Quercetin alleviates rat osteoarthritis by inhibiting inflammation and apoptosis of chondrocytes, modulating synovial macrophages polarization to M2 macrophages.
GRK2 Mediated Abnormal Transduction of PGE2-EP4-cAMP-CREB Signaling Induces the Imbalance of Macrophages Polarization in Collagen-Induced Arthritis Mice.
Rice Protein Exerts Anti-Inflammatory Effect in Growing and Adult Rats via Suppressing NF-κB Pathway.
Trans-10-hydroxy-2-decenoic acid alleviates LPS-induced blood-brain barrier dysfunction by activating the AMPK/PI3K/AKT pathway.
Interleukin-1 receptor associated kinase (IRAK)-M -mediated type 2 microglia polarization ameliorates the severity of experimental autoimmune encephalomyelitis (EAE).
Microglia Activated by Excess Cortisol Induce HMGB1 Acetylation and Neuroinflammation in the Hippocampal DG Region of Mice Following Cold Exposure.
Icariin attenuates neuroinflammation and exerts dopamine neuroprotection via an Nrf2-dependent manner.
Targeted Delivery of miRNA 155 to Tumor Associated Macrophages for Tumor Immunotherapy.
Aryl Hydrocarbon Receptor Regulates Apoptosis and Inflammation in a Murine Model of Experimental Autoimmune Uveitis.
Effects of Acute Cold Stress After Long-Term Cold Stimulation on Antioxidant Status, Heat Shock Proteins, Inflammation and Immune Cytokines in Broiler Heart.
Effective Amelioration of Liver Fibrosis Through Lentiviral Vector Carrying Toxoplasma gondii gra15(II) in Murine Model.
Fangchinoline Ameliorates the Expressions of Angiogenic Molecule in Cerebral Ischemia Induced Neuronal Degeneration in Neonatal Rats.
Neuroprotective Effects of dl-3-n-Butylphthalide against Doxorubicin-Induced Neuroinflammation, Oxidative Stress, Endoplasmic Reticulum Stress, and Behavioral Changes.
Flavonoid-Rich Ethanol Extract from the Leaves of Diospyros kaki Attenuates D-Galactose-Induced Oxidative Stress and Neuroinflammation-Mediated Brain Aging in Mice.
Ingredients from Litsea garrettii as Potential Preventive Agents against Oxidative Insult and Inflammatory Response.
Berberine Protects Secondary Injury in Mice with Traumatic Brain Injury Through Anti-oxidative and Anti-inflammatory Modulation.
GABAB receptor mediate hippocampal neuroinflammation in adolescent male and female mice after cold expose.
Astragaloside IV improves vascular endothelial dysfunction by inhibiting the TLR4/NF-κB signaling pathway.
S100A8/A9 induces microglia activation and promotes the apoptosis of oligodendrocyte precursor cells by activating the NF-κB signaling pathway.
Diosmetin Attenuates Akt Signaling Pathway by Modulating Nuclear Factor Kappa-Light-Chain-Enhancer of Activated B Cells (NF-κB)/Inducible Nitric Oxide Synthase (iNOS) in Streptozotocin (STZ)-Induced Diabetic Nephropathy Mice.
Decidual macrophage M1 polarization contributes to adverse pregnancy induced by Toxoplasma gondii PRU strain infection.
l-Arginine induces antioxidant response to prevent oxidative stress via stimulation of glutathione synthesis and activation of Nrf2 pathway.
Silica-induced initiation of circular ZC3H4 RNA/ZC3H4 pathway promotes the pulmonary macrophage activation.
Lipopolysaccharide Induces Subacute Cerebral Microhemorrhages with Involvement of Nitric Oxide Synthase in Rats.
Anti-inflammatory effect of tranexamic acid against trauma-hemorrhagic shock-induced acute lung injury in rats.
Investigation of constituents from Cinnamomum camphora (L.) J. Presl and evaluation of their anti-inflammatory properties in lipopolysaccharide-stimulated RAW 264.7 macrophages.
Asperuloside and Asperulosidic Acid Exert an Anti-Inflammatory Effect via Suppression of the NF-κB and MAPK Signaling Pathways in LPS-Induced RAW 264.7 Macrophages.
Photobiomodulation therapy promotes neurogenesis by improving post-stroke local microenvironment and stimulating neuroprogenitor cells.
Toxoplasma gondii GRA15(II) effector-induced M1 cells ameliorate liver fibrosis in mice infected with Schistosomiasis japonica.
Tempol relieves lung injury in a rat model of chronic intermittent hypoxia via suppression of inflammation and oxidative stress.
Protective effect of the ethanol extract from Ligusticum chuanxiong rhizome against streptozotocin-induced diabetic nephropathy in mice.
Quercetin ameliorates kidney injury and fibrosis by modulating M1/M2 macrophage polarization.
NOD2 promotes dopaminergic degeneration regulated by NADPH oxidase 2 in 6-hydroxydopamine model of Parkinson's disease.
Fish oil supplementation attenuates neuroinflammation and alleviates depressive-like behavior in rats submitted to repeated lipopolysaccharide.
Butaselen prevents hepatocarcinogenesis and progression through inhibiting thioredoxin reductase activity.
Treadmill Exercise Exerts Neuroprotection and Regulates Microglial Polarization and Oxidative Stress in a Streptozotocin-Induced Rat Model of Sporadic Alzheimer's Disease.
Iridoids with Genipin Stem Nucleus Inhibit Lipopolysaccharide-Induced Inflammation and Oxidative Stress by Blocking the NF-κB Pathway in Polycystic Ovary Syndrome.
NS1 of H7N9 Influenza A Virus Induces NO-Mediated Cellular Senescence in Neuro2a Cells.
Peli1 Contributions in Microglial Activation, Neuroinflammatory Responses and Neurological Deficits Following Experimental Subarachnoid Hemorrhage.
Adulthood Exposure to Lipopolysaccharide Exacerbates the Neurotoxic and Inflammatory Effects of Rotenone in the Substantia Nigra.
GRP78 plays an integral role in tumor cell inflammation-related migration induced by M2 macrophages.
NF-κB-mediated inflammation correlates with calcium overload under arsenic trioxide-induced myocardial damage in Gallus gallus.
Hepatoprotective effect of quercetin against LPS/d-GalN induced acute liver injury in mice by inhibiting the IKK/NF-κB and MAPK signal pathways.
A novel IL-1RA-PEP fusion protein with enhanced brain penetration ameliorates cerebral ischemia-reperfusion injury by inhibition of oxidative stress and neuroinflammation.
Reactive oxygen species-responsive polymeric nanoparticles for alleviating sepsis-induced acute liver injury in mice.
Procyanidins extracted from the litchi pericarp ameliorate atherosclerosis in ApoE knockout mice: their effects on nitric oxide bioavailability and oxidative stress.
Matrine promotes NT3 expression in CNS cells in experimental autoimmune encephalomyelitis.
Alantolactone induces apoptosis, promotes STAT3 glutathionylation and enhances chemosensitivity of A549 lung adenocarcinoma cells to doxorubicin via oxidative stress.
Quillaja saponaria bark saponin protects Wistar rats against ferrous sulphate-induced oxidative and inflammatory liver damage.
The inflammatory responses in Cu-mediated elemental imbalance is associated with mitochondrial fission and intrinsic apoptosis in Gallus gallus heart.
Inflammatory and oxidative stress‑associated factors in chronic intermittent hypoxia in Chinese patients, rats, lymphocytes and endotheliocytes.
CAPE-pNO(2) ameliorated diabetic nephropathy through regulating the Akt/NF-κB/ iNOS pathway in STZ-induced diabetic mice.
Melatonin ameliorates restraint stress-induced oxidative stress and apoptosis in testicular cells via NF-κB/iNOS and Nrf2/ HO-1 signaling pathway.
Neuroprotective effects of Kaempferide-7-O-(4″-O-acetylrhamnosyl)-3-O-rutinoside on cerebral ischemia-reperfusion injury in rats.
Ghrelin protects against palmitic acid or lipopolysaccharide-induced hepatocyte apoptosis through inhibition of MAPKs/iNOS and restoration of Akt/eNOS pathways.
Long Chain Omega-3 Polyunsaturated Fatty Acid Supplementation Alleviates Doxorubicin-Induced Depressive-Like Behaviors and Neurotoxicity in Rats: Involvement of Oxidative Stress and Neuroinflammation.
SENP1 inhibits the IH-induced apoptosis and nitric oxide production in BV2 microglial cells.
Protective Effect of the Total Saponins from Rosa laevigata Michx Fruit against Carbon Tetrachloride-Induced Liver Fibrosis in Rats.
Tetrachloro-p-benzoquinone induces hepatic oxidative damage and inflammatory response, but not apoptosis in mouse: the prevention of curcumin.
Effects of the total saponins from Rosa laevigata Michx fruit against acetaminophen-induced liver damage in mice via induction of autophagy and suppression of inflammation and apoptosis.
Protective effect of flavonoid-rich extract from Rosa laevigata Michx on cerebral ischemia-reperfusion injury through suppression of apoptosis and inflammation.
Protection of the flavonoid fraction from Rosa laevigata Michx fruit against carbon tetrachloride-induced acute liver injury in mice.
Xu D, Lian L, Luo Z, Dong Y, He C, Chu M, Lu L, Ma W, Gan K
Biomaterials research 2026;30:0344
Biomaterials research 2026;30:0344
Photocrosslinkable Chitosan Quaternary Ammonium Salt-Based Ternary Hydrogel with Fibroblast Growth Factor 21 for Diabetic Wound Healing.
Hu J, Xu Y, Zhou D, Chen K, Jiang J, Lin M, Chen W, Wu J, Jiang H, Zhu M, Zhang B, Xu K, Wei P
Biomaterials research 2026;30:0309
Biomaterials research 2026;30:0309
Lnc-CHRM4-2:1 Inhibits M2 Polarization and Efferocytosis of Macrophages by Downregulating MerTK and SLC2A1 in Rheumatoid Arthritis.
Chu J, Zang J, Zhang L, Qu Z, Li H, Yang C, Sun J, Gai L, Sun X, Xu D
Journal of immunology research 2026;2026(1):e1718207
Journal of immunology research 2026;2026(1):e1718207
Targeting Pulmonary Hypertension: Elucidating Sophocarpine's Protective Role via Preclinical Models.
Xie F, Feng J, Li K, Chen Y, Han L, Wu Y
Mediators of inflammation 2026;2026:5524066
Mediators of inflammation 2026;2026:5524066
The mechanism of Vicenin-2 in ameliorating skin photoaging: involvement of m6A-modified macrophage polarization.
Zhou Y, Shuai W, Peng X, Li R, Chen M, Tan B, Mu Y, Duan X
Frontiers in pharmacology 2026;17:1778993
Frontiers in pharmacology 2026;17:1778993
Gomphus floccosus (Schw.) Sing. extract attenuates alcoholic liver disease by suppressing macrophage glycolysis and M1 polarization.
Ruan T, Li X, Li M, Wang S, Shen L, Liu C, Peng Y, Tao Y
Frontiers in immunology 2026;17:1772592
Frontiers in immunology 2026;17:1772592
ROS-Responsive Double-Layer Microneedles Enable Sequential Antibacterial and Immunomodulatory Therapy for Infected Wound Healing.
Zhang H, Wang Z, Zhu Y, Huang T, Xiu Z, Huang H, Li H, Xie J, Huang H, Liu M, Sun L, Lan Y, Guo L
Theranostics 2026;16(4):2052-2079
Theranostics 2026;16(4):2052-2079
CCL5 promotes angiotensin II-induced cardiac remodeling through regulation of platelet-driven M2 macrophage polarization.
Lv S, Zhou M, Li T, Zeng Z, Yan Z, Hou Y, Yang L, Zhang F, Zhao W, Zhou Y, Yang M
Theranostics 2026;16(2):689-711
Theranostics 2026;16(2):689-711
ZEB1 maintains mitochondrial fission and macrophage efferocytosis by restraining MFN2, thereby limiting inflammation and improving tendon‑bone healing.
Zhao Y, Zhang Y, Lei T, Zhang S, Nan K, Zhang X, Fan LH
International journal of molecular medicine 2026 May;57(5)
International journal of molecular medicine 2026 May;57(5)
Asperuloside-Mediated Activation of Nrf2 Inhibits the NF-κB Pathway and Suppresses Osteoarthritis Progression.
Zhu L, Shen H, Huang C, Jiang H, Yan Z, Pan X, Lu Z
Phytotherapy research : PTR 2026 May;40(5):3027-3046
Phytotherapy research : PTR 2026 May;40(5):3027-3046
Combination of Hypoxia-Preconditioned ADSCs and Deferoxamine Can Speed Up the Healing of Diabetic Wounds by Promoting Angiogenesis and Regulating Macrophage Polarization.
Cai F, Chen W, Li Q, Chen S, Xu Y, Ren Y, Liu Y
Stem cell reviews and reports 2026 May;22(4):1811-1826
Stem cell reviews and reports 2026 May;22(4):1811-1826
Edible Bird's Nest Attenuates Neuroinflammation and Cognitive Impairment in a Model of Chronic Fatigue Syndrome.
Wang X, Wang D, Chai Y, Zhang Y, Wang H, Qu T, Zhang W, Yuan M, Gao S, Sun Y, Li Y
Food science & nutrition 2026 May;14:e71685
Food science & nutrition 2026 May;14:e71685
Ultrasound Activated Piezoelectric Dural Patches to Drive Endogenous Neural Stem Cell-Mediated Repair Traumatic Brain Injury.
Zhou P, Wu Q, Wu Y, Huang R, Li W, Niu H, Sun H, Liu H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 May;13(27):e24326
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 May;13(27):e24326
Taohong Siwu decoction and its components regulate the M1/M2 polarization of macrophages to alleviate inflammatory injury in sepsis via the RAGE.
Han X, Pang M, Hu C, Li Y, Xu T, Xu H, Ye H, Xie L, Shen A, Liu B, Zhang G, Zhou Y
Journal of ethnopharmacology 2026 May 10;362:121366
Journal of ethnopharmacology 2026 May 10;362:121366
Persistent histone H3K27 acetylation contributes to excessive scar formation after spinal cord injury through the regulation of microglial cholesterol accumulation.
Qiao Q, Gong Q, Li N, Sun H, Ru X, Mu N, Chen B, Li W, Chen T, Feng H, Chen Y, Cheng H
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2026 Mar;23(2):e00868
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2026 Mar;23(2):e00868
Cascade Therapy of Periodontitis via Sequential Release of Ribosome-Targeting Antimicrobial Peptide and Irisin From a Multifunctional MOF-Based System.
Chen Y, Xu Z, Xue Y, Liu S, Zhang X, Guo J, Yao M, Liu Y, Lu X, Qian J, Ma Q
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar;13(18):e21553
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar;13(18):e21553
Early Radial Extracorporeal Shockwave Stimulation on Proximal Tibial Circular Osteotomy Site Enhanced Heterotopic Skin Wound Healing via Small Extracellular Vesicles.
Xie X, Bi S, Su B, Zhou R, Li X, Yan Z, Zhou X, Wang F, Yu T
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar;13(16):e17257
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar;13(16):e17257
Targeting Microglial CD49a Inhibits Neuroinflammation and Demonstrates Therapeutic Potential for Parkinson's Disease.
Lu H, Zhu Y, Wang X, Wu Z, Xu Z, Chen R, Guo Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar;13(13):e15138
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar;13(13):e15138
Royal jelly protein hydrolysates accelerate in vitro diabetic wound healing by enhancing keratinocytes functions and suppressing macrophage-mediated inflammation.
Lin T, Huang L, Lin A, Yuan Y, Cai R, Lin Z, Wang L, Lin Y, Su S
BMC complementary medicine and therapies 2026 Mar 9;26(1)
BMC complementary medicine and therapies 2026 Mar 9;26(1)
Vericiguat Attenuates Post-Myocardial Infarction Inflammation Associated With Macrophage Polarization and Regulation of the Survivin/Caspase-6 Pathway.
Zhao Y, Li H, Wu Z, Yin Y, Wang H, Zhang L, Zhang Y, Jiang B, Jiang T, Li H
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Mar 31;40(6):e71635
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Mar 31;40(6):e71635
IL-3 Modulates Microglia Polarization and Attenuates Neuroinflammation in Traumatic Brain Injury.
Huang N, Zhang Q, Chen Y, Yu D, Liu R, Kang J, Fang X, Zhang Y, Bian H, Zhao Y, Yin Y, Zhang C, Jia Y, Chen Q, Fang Y, Li S, Li F, Jin Z, Ning B
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar 31;:e04511
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar 31;:e04511
Cordycepin alleviates ischaemic brain injury by suppressing microglia-induced neuroinflammation via regulating the Notch1 signalling pathway.
Li X, Zhan GF, Zhang X, Zhao YL, Mao M, Xia Q
British journal of pharmacology 2026 Mar 30;
British journal of pharmacology 2026 Mar 30;
Human umbilical cord mesenchymal stem cells alleviate hypoxic-ischemia-induced white-matter injury in neonatal rats by regulating polarization of microglia.
Wang C, Xu QQ, Zhang SJ, Zhu YP
Scientific reports 2026 Mar 3;16(1)
Scientific reports 2026 Mar 3;16(1)
Exercise reverses high-fat diet-induced perivascular adipose tissue dysfunction through modulation of UCP2 and TXNIP/NLRP3 pathways.
Hu J, Jiang X, Ding M, Lee SK, Wang L, Li T, Li W, Korivi M
Journal of physiology and biochemistry 2026 Mar 2;82(1)
Journal of physiology and biochemistry 2026 Mar 2;82(1)
α-Ketoglutarate protects against cartilage damage via epigenetically driven metabolic reprogramming in osteoarthritis models.
Li S, Huang J, Shang T, Lu L, Fan OR, Jin P, Zou X, Cai Z, Lu W, Jia S, Li L, Fang K, Niu F, Li J, Zhao C, Wang Q, Sun R, Shi S, Yin F, Zhang Y, Sun YE, Cui L
The Journal of clinical investigation 2026 Mar 2;136(5)
The Journal of clinical investigation 2026 Mar 2;136(5)
Tanshinone IIA-pretreated mesenchymal stem cells alleviate neuroinflammation in 3×Tg-AD mice via the TREM2/PI3K/Akt pathway.
Wu J, Ge Y, Zhang L, Huang J, Huang N, Luo Y
Stem cell research & therapy 2026 Mar 17;17(1)
Stem cell research & therapy 2026 Mar 17;17(1)
ROS-Responsive Prodrug Containing Dihydroartemisinin and Cinnamaldehyde for the Potential Treatment of Nonalcoholic Steatohepatitis.
Hao R, Sun Y, Wang C, Wang Y, Li L, Sun H, Chen L
ACS applied materials & interfaces 2026 Mar 11;18(9):13384-13397
ACS applied materials & interfaces 2026 Mar 11;18(9):13384-13397
The engineered probiotic strain Lactococcus lactis MG1363-pMG36e-GLP-1 regulates microglial polarization and gut dysbiosis in a transgenic mouse model of Parkinson's disease.
Yue M, Chen T, Chen W, Wei J, Liao B, Zhang J, Li F, Hong D, Fang X
Neural regeneration research 2026 Mar 1;21(3):1211-1221
Neural regeneration research 2026 Mar 1;21(3):1211-1221
Exosomal lncRNA OTUD6B-AS1 as a pathogenic nanocarrier promotes inflammatory macrophage polarization in endometritis via a targetable ceRNA circuit.
Yang J, Chen Y, Wang K, Mi L, Chen Y, Li X, Yin G, Jiang K
Materials today. Bio 2026 Jun;38:103027
Materials today. Bio 2026 Jun;38:103027
AICAR improves depression-like behaviors and is associated with hippocampal AMPK activation and modulation of neurogenesis and neuroinflammation in a microbiota disruption model.
Takahashi K, Kurokawa K, Kawaguchi R, Takeda H, Tsuji M
Neurochemistry international 2026 Jun;196:106152
Neurochemistry international 2026 Jun;196:106152
Integrated whole transcriptome sequencing, network pharmacology and in vivo validation reveal that Compound Wufengcao Liquid promotes pressure injury healing via PPARγ-mediated macrophage polarization.
Deng R, Qian J, Bu Q, Cao T, Liu Y, Gao M, Huang Z
Fitoterapia 2026 Jun;191:107260
Fitoterapia 2026 Jun;191:107260
Qingjin Pingchuan formula attenuates pulmonary inflammation by reprogramming neutrophil SHP1-JAK2/SRC-STAT3 signaling.
Zhang Y, Yue R, Zhang L, Ji Y, Shi R, Zhou Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158063
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158063
Cannabidiol synergizes with methotrexate to attenuate rheumatoid arthritis via STAT3/NF-κB signalling-mediated M1 macrophage polarization.
Xu J, Wang Z, Geng Q, Wen C, Jiao Y, Deng T, Shi T, Wang Y, Deng T, Xiao C
International immunopharmacology 2026 Jun 15;179:116627
International immunopharmacology 2026 Jun 15;179:116627
A potent icaritin derivative ameliorates Parkinson's disease via GPER-mediated mitophagy restoration and dopaminergic neuroprotection.
Wang X, Cao X, Cai M, Zhao R, Zheng Y, Zhang M, Shao C, Chen W
Bioorganic chemistry 2026 Jun 15;174:109759
Bioorganic chemistry 2026 Jun 15;174:109759
Momordin Ic alleviates inflammation and skin barrier dysfunction of atopic dermatitis in vitro and in vivo.
Yang N, Dai H, Jin H, Liu C, Xu L, Liu Y
Journal of ethnopharmacology 2026 Jun 12;364:121489
Journal of ethnopharmacology 2026 Jun 12;364:121489
Cu(2+)-chelated epigallocatechin gallate nanoparticle-functionalized hydrogel promotes osteogenesis by inhibiting ferroptosis.
Li C, Li J, Chen S, Xia J, Song J, Hu T, Cui Z, Gu G, Chen F, Mei Z, Ding Y, Xie D, Wu X, Shao J, Du Y, Zheng L, Hu C, Xi Y
Journal of controlled release : official journal of the Controlled Release Society 2026 Jun 10;394:114840
Journal of controlled release : official journal of the Controlled Release Society 2026 Jun 10;394:114840
Celastrol ameliorates depressive-like behaviors in a rat model of post-stroke depression and is associated with reduced neuroinflammation and restoration of serotonergic- and synaptic-related proteins.
Zheng Y, Zhang P, Xie Q, Cao F, Xu L
Brain research bulletin 2026 Jun 1;239:111855
Brain research bulletin 2026 Jun 1;239:111855
A composite sustained-release system with immunomodulatory and synergistic osteogenic differentiation effects for repairing inflammatory alveolar bone defects.
Lv T, Chen Y, Li N, Heng Y, Su X, Zhang Y, Jiang Y, Guo Y, Hu K
Biomaterials advances 2026 Jul;184:214837
Biomaterials advances 2026 Jul;184:214837
Dragon's blood and its active components ameliorate pressure overload-induced heart failure via remodeling of cardiac lymphatics.
Xiang Z, Wang F, Zhang P, Peng J, Wang P, Zhang J
Journal of ethnopharmacology 2026 Jul 15;366:121595
Journal of ethnopharmacology 2026 Jul 15;366:121595
Sodium Houttuyfonate improves cognitive impairment in mice after chronic sleep deprivation by inhibiting microglial inflammation and ferroptosis.
Li R, Zhu Y, Wei H, Yu M, Xu Y
International immunopharmacology 2026 Jul 1;180:116688
International immunopharmacology 2026 Jul 1;180:116688
Targeting of CIRP attenuates osteoarthritis progression via suppressing TLR4/NF‑κB/NLRP3 signaling axis.
Sun W, Liao Y, Feng J, Liang J, He Q, Cui Y, Huang D, Shi H, You W, Sun W, Yi Q
International journal of molecular medicine 2026 Jan;57(1)
International journal of molecular medicine 2026 Jan;57(1)
Ecdysteroid-enriched fraction of Cyathula officinalis suppresses synovial proliferation and inflammation to ameliorate RA by inhibiting the AKT/PI3K/mTOR signaling pathway.
Huang YH, Qiu L, Peng Y, Cai R, Xiao QQ, Li MC, Xu LJ, Fu Q
Journal of Asian natural products research 2026 Jan;28(1):175-197
Journal of Asian natural products research 2026 Jan;28(1):175-197
Down-regulation of lipocalin-2 alleviates depressive-like behaviors in mice through modulation of microglial activation.
Yu X, Gao S, Chen Y, Ye L, Wang B, Xu L, Sun A, Liang C, Lu S, Li X, Fan Z, Wang Y
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2026 Jan;23(1):e00862
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2026 Jan;23(1):e00862
SS-31 improves post-cardiac arrest brain injury by inhibiting microglial ferroptosis and polarization.
Jiang T, Zhang H, Sun Y, Ji X, Xue L, Pan C, Guo Y, Xu F
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2026 Jan;23(1):e00772
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2026 Jan;23(1):e00772
Oligosaccharide esters from Polygala paniculata with their NO inhibitory activity.
Quang TH, Cham PT, Hanh TTH, Anh DV, Nam NH, Vuong NQ, Ngan NTT
Fitoterapia 2026 Jan;188:107027
Fitoterapia 2026 Jan;188:107027
Adipose-derived stem cells (ADSCs)-derived DKK1 promotes cutaneous wound healing by inducing M2 macrophage polarization via PI3K/AKT and JNK activation.
Liu D, Liu N, Liu X, Liu Y, Zhang H, Zhou Z, Zheng J, Tian Y
Biochimica et biophysica acta. Molecular cell research 2026 Jan;1873(1):120077
Biochimica et biophysica acta. Molecular cell research 2026 Jan;1873(1):120077
Limosilactobacillus reuteri DSM17938 Attenuates Neuroinflammatory Responses After Spinal Cord Injury by Modulating Tryptophan Metabolism.
Cen Q, Cui Y, Feng J, Zhu L, Wei J, Wang L, Chang C, Pang R, Wang J, Zhang A
Probiotics and antimicrobial proteins 2026 Jan;18(1):583-601
Probiotics and antimicrobial proteins 2026 Jan;18(1):583-601
T1WI-SWI Dual Modal Magnetic Resonance Nanoprobes for Accurate Diagnosis of Early Stage Alzheimer's Disease.
Li M, Shen A, Gao X, Lin C, Huang Z, Lv Q, Tang J, Ma X, Ni J, Tian J, Wu J, Xu X, Wang W, Wang P
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(1):e10298
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(1):e10298
Neuropeptide SP protects against colitis and linked anxiety-like behavior through the putative roles of gut microbiota and metabolite inositol.
Lan J, Wang J, Huang S, Li C, Deng Z, Hao Z, Ma Y
Nature communications 2026 Jan 8;17(1):295
Nature communications 2026 Jan 8;17(1):295
Asiatic Acid Attenuates Salmonella typhimurium-Induced Neuroinflammation and Neuronal Damage by Inhibiting the TLR2/Notch and NF-κB Pathway in Microglia.
Zou W, Li J
International journal of molecular sciences 2026 Jan 7;27(2)
International journal of molecular sciences 2026 Jan 7;27(2)
Propyl Gallate Attenuates Cognitive Deficits Induced by Chronic Sleep Deprivation Through Nrf2 Activation and NF-κB Inhibition.
Zhang X, Cui J, Liu L, Sun J, Fan B, Wang F, Lu C
Antioxidants (Basel, Switzerland) 2026 Jan 7;15(1)
Antioxidants (Basel, Switzerland) 2026 Jan 7;15(1)
Mechanism of ultrasound-guided renal parenchymal injection of MSCs for the treatment of chronic kidney disease: down-regulated SGK1 promotes M2 macrophage polarization.
Wan S, Tang D, Yang Z, Zeng Y, Hu L, Zhu L, Xia C, Bao F, Ke C, Wang J
European journal of medical research 2026 Jan 6;31(1):211
European journal of medical research 2026 Jan 6;31(1):211
Anti-tumor effect of flavonoids isolated from Bidens Pilosa L. by regulating the activity of myeloid-derived suppressor cells within the tumor microenvironment in mice.
Tao Y, Du M, Zhu M, Sun W, Zeng G, Xiong J, Li J, Yang Z, Fan B, Zhang R, Zeng G
Journal of ethnopharmacology 2026 Jan 30;355(Pt A):120635
Journal of ethnopharmacology 2026 Jan 30;355(Pt A):120635
Single-cell transcriptomics uncover RNF130-mediated TNF-α pathway activation and worenine synergy with paclitaxel in breast cancer.
Hu M, Huang L, Deng H, Chen Z, Cheng G, Liu X
Clinical epigenetics 2026 Jan 24;18(1):32
Clinical epigenetics 2026 Jan 24;18(1):32
Rewiring brain structural and functional disconnection with acupuncture in rat model of vascular cognitive impairment and dementia.
Wang L, Zhao JP, Cao Y, Ma SM, Yang JW, Su XT, Huang J, Wang QY, Liu CZ
Biological research 2026 Jan 19;59(1):10
Biological research 2026 Jan 19;59(1):10
Hydrogel with cell-cell adhesion cues enhances neural regeneration.
Tang X, Zhang S, Liu M, Liang Y, Fan Y, Sun X, He C, Yang X, Zhu R, Jin X, Zhuang Q, Ge Y, Ling J, Yang Y
Nature communications 2026 Jan 19;17(1)
Nature communications 2026 Jan 19;17(1)
Propyl Gallate Mitigates Gastric Injury Caused by Indomethacin in Wistar Rats.
Widodo F, Wang YY, Yen TB, Tseng KC, Chen YH, Lin SC, Tsai PS, Chen YK
Journal of agricultural and food chemistry 2026 Jan 14;74(1):941-951
Journal of agricultural and food chemistry 2026 Jan 14;74(1):941-951
The mechanism of indigo naturalis and its active ingredients against ulcerative colitis.
Ma KY, Hou BL, Fan AQ, Huang AL, Li BR, Liang YN, Wang Z
Scientific reports 2026 Jan 14;16(1):5220
Scientific reports 2026 Jan 14;16(1):5220
Bioactive nanoparticles from clam extracts mitigate alcoholic liver injury by modulating multiple pathways.
Kuo YR, Lo KJ, Pan MH
NPJ science of food 2026 Jan 12;10(1):53
NPJ science of food 2026 Jan 12;10(1):53
Taurine-loaded covalent organic frameworks for alleviating post-radiation bone regeneration disorder.
Chen H, Yang X, Ruan H, Wang X, Zheng M, Zeng G, He Y
Journal of controlled release : official journal of the Controlled Release Society 2026 Jan 10;389:114492
Journal of controlled release : official journal of the Controlled Release Society 2026 Jan 10;389:114492
Inulin with different degrees of polymerization adopts different strategies to mitigate radiation-induced intestinal injury: focus on intestinal epithelial or T cell homeostasis.
Ji K, Jia X, Lu X, Zhang D, Du L, Wang J, Wang Y, Song H, He N, Xu C, Gu Y, Yang M, Dong J, Yuan Y, Li J, Zhang M, Liu Q
Carbohydrate polymers 2026 Jan 1;371:124490
Carbohydrate polymers 2026 Jan 1;371:124490
Effect and Mechanism of Apoptotic Bodies from Inflammatory Periodontal Ligament Stem Cells on Macrophage M1 Polarisation.
Weng J, Zhang Z, Zeng L, Xia J, Xu Z, Zhu G, Zhang H, Wang J, Pathak JL, Yu L
International dental journal 2026 Feb;76(1):103981
International dental journal 2026 Feb;76(1):103981
Inhibition of Setd7 protects against cardiomyocyte hypertrophy via inhibiting lipid oxidation.
Su HB, Wang JH, Zhang YY, Xu J, Liu JY, Li YH, Xiao CX, Wang CY, Chang J, Liu XH
Acta pharmacologica Sinica 2026 Feb;47(2):344-356
Acta pharmacologica Sinica 2026 Feb;47(2):344-356
Integrating TWAS, chemical-genomic networks, and experimental models: melatonin as a ferroptosis inhibitor in osteoarthritis therapy.
Feng R, Aihaiti Y, Yu H, Xu K, Lu C, Xu P
Clinical rheumatology 2026 Feb;45(2):1559-1572
Clinical rheumatology 2026 Feb;45(2):1559-1572
Neuroprotective Effects of Salvia Miltiorrhiza-Derived Extracellular Nanovesicles in Traumatic Brain Injury.
Chen BB, Wang Y, Li YN, Han CC, Guo JX, Meng JJ, Sun WX, Kong WH, Feng L, Rong R, Jiang P
Journal of neurotrauma 2026 Feb;43(3-4):295-316
Journal of neurotrauma 2026 Feb;43(3-4):295-316
Pressure-sensitive composite bandages with high toughness, self-healability and strong tissues adhesion for rapid bone fixation and accelerated osteogenesis via immunomodulation and neovascularization.
Lei P, Wang S, Chen K, Wang L, Shen Y, Zhong H, Chen S, Su X, Zhao Y, Wang H, Li L
Materials today. Bio 2026 Feb;36:102730
Materials today. Bio 2026 Feb;36:102730
4D-printed Fe3O4-PLLA scaffolds modulate osteoimmune microenvironment for oral bone repair.
Song W, Huang W, Du Z, Xiao C, Qu J, Xu W, Liu X
Materials today. Bio 2026 Feb;36:102691
Materials today. Bio 2026 Feb;36:102691
Piezo1 mediated scaffold-free rapid generation of self-mineralized bone organoids via activating Wnt signaling.
Zhang L, Zhang Y, Wan Z, Yuan X, Gao Y, Song R, Liu X, Sang J, Song J, Wang Y, Zhao Y, Yuan Z
Materials today. Bio 2026 Feb;36:102620
Materials today. Bio 2026 Feb;36:102620
Apigenin alleviates DFZ-induced cardiac, renal, and intestinal injury in carp by modulating oxidative stress and inflammatory responses.
Guan T, Zhou W, Gao Y, Dong Q, Jin X, Li Y, Xu Z, Yu H, Dong J
Fish & shellfish immunology 2026 Feb;169:111054
Fish & shellfish immunology 2026 Feb;169:111054
Microfluidics-Inspired Microgels with Intrinsic Bioactivity for Advanced Burn Wound Therapy.
Liu Z, Wu H, Wang X, Wu X, Wu H, An X, Chen J
Advanced healthcare materials 2026 Feb;15(6):e02477
Advanced healthcare materials 2026 Feb;15(6):e02477
Inhalation of mesenchymal stromal cell-derived extracellular vesicles activates macrophage polarization through the miR-22-3p/NLRP3/IL-1β pathway, ameliorating lung ischemia - reperfusion injury.
Wang T, Wu G, Gao P, Zhuang F, Wang Z, Zhou Z, Li C, Wu J, Zhao D
Stem cell research & therapy 2026 Feb 9;17(1)
Stem cell research & therapy 2026 Feb 9;17(1)
hsa_circ_0006168 drives microglial activation in TNC via miR-99b-5p/KDM6B axis to promote central sensitization in migraine.
Chen Q, Zhai Q, Lin J, Huang Y, Li H, Zhang C, Yu Q, Sun T, Pan Y
The journal of headache and pain 2026 Feb 7;27(1)
The journal of headache and pain 2026 Feb 7;27(1)
Mangosteen (Garcinia mangostana) Pericarp and Leaf Tinctures Inhibit LPS-Induced Pro-Inflammatory Responses in Macrophages and Activate Nrf2.
Tocmo R, Nauman MC, Huang Y, Subedi P, Johnson JJ
Nutrients 2026 Feb 5;18(3)
Nutrients 2026 Feb 5;18(3)
Saussurea involucrata oral liquid alleviates joint inflammation in CIA rats by modulating macrophage polarization and glucose metabolism.
Maimaitituersun S, Mijiti W, Cong S, Zhao X, Zhou Z, Ji P, Luo L
BMC immunology 2026 Feb 3;27(1)
BMC immunology 2026 Feb 3;27(1)
AE-MXene-modified titanium alloy promotes osseointegration by regulating the AMPK-MTOR-autophagy pathway in macrophage.
Chao R, Sun L, Xu X, Liu Z, Xu X, Ren Z, Chen X, Xu W, Chen X, Hu Y, Zhang S
Journal of nanobiotechnology 2026 Feb 3;24(1):130
Journal of nanobiotechnology 2026 Feb 3;24(1):130
Kynurenic Acid/GPR35 Signaling Protects the Infarcted Heart by Suppressing Macrophage mtDNA-Triggered cGAS-STING Activation.
Mao Y, Jiao J, Zhu X, Liu W, He S, Li N, Yang H, Li J, Tang T, Xia N, Cheng X
Antioxidants (Basel, Switzerland) 2026 Feb 27;15(3)
Antioxidants (Basel, Switzerland) 2026 Feb 27;15(3)
Integration of Bulk and Single-Cell Transcriptomics Reveals Prognostic and Immunological Roles of MTHFD2 in Clear Cell Renal Cell Carcinoma.
Zhou Y, Zheng X, Ye P, Yang H
International journal of molecular sciences 2026 Feb 20;27(4)
International journal of molecular sciences 2026 Feb 20;27(4)
Phosphoglycerate dehydrogenase-mediated serine reprogramming aggravates macrophage hyperinflammation in murine Pseudomonas aeruginosa pneumonia.
Chen R, Zeng R, Shi M, Zhang G, Wang F, Yang Q, Jiang Y, Zhang Y, Li Y, Qu J
Nature communications 2026 Feb 20;17(1)
Nature communications 2026 Feb 20;17(1)
Ultraviolet-induced Glycyrrhiza polysaccharide hydrogels with different mechanical strength for wound management.
Wang Z, Luo M, Ni L, Li Y, Liu D, Zhu H, Xia B, Liu Y, Liu Q, Yang B
Carbohydrate polymers 2026 Feb 15;374:124712
Carbohydrate polymers 2026 Feb 15;374:124712
Houttuynia cordata Polysaccharide Alleviates Hepatic Ischemia-Reperfusion Injury by Regulating Macrophage Polarization via Inhibiting the TLR4/NF-κB Signaling Pathway.
Yu B, He D, Chen Z, Zhou Y, Zhou J, Wang T, Qiu Q, Chen Z, Ma X, Zhu J, Zheng S, Qiu T
Biomedicines 2026 Feb 14;14(2)
Biomedicines 2026 Feb 14;14(2)
An immunomodulatory hydrogel featuring antibacterial and ROS-scavenging functions for enhanced burn wound healing.
Zhao XS, Zhang LP, Wang G, Yang QY, Cheng XJ, Wu CY, Wu D, Dong CB, Yang YT, Wang YF, Cai XJ, Zhu NW
Journal of nanobiotechnology 2026 Feb 13;24(1)
Journal of nanobiotechnology 2026 Feb 13;24(1)
A dual-action nanoparticle approach for spinal cord injury treatment: ferroptosis inhibition, inflammation control, and Myelin preservation.
Xue C, Zhou Y, Lin H, Li Z, Xiao Y, Yang J, Lu M, Qin Y, Song D, Chen W, Xu J, Zuo Y, Wang Z, Jiang C
Journal of nanobiotechnology 2026 Feb 12;24(1):158
Journal of nanobiotechnology 2026 Feb 12;24(1):158
Blood-brain barrier disruption and neuroinflammation in the hippocampus of a cardiac arrest porcine model: Single-cell RNA sequencing analysis.
Jiang T, Li Y, Liu H, Sun Y, Zhang H, Zhang Q, Tang S, Niu X, Du H, Yu Y, Yue H, Guo Y, Chen Y, Xu F
Neural regeneration research 2026 Feb 1;21(2):742-755
Neural regeneration research 2026 Feb 1;21(2):742-755
lncRNA MALAT1-mediated regulation of cholesterol-oxidative stress-iron metabolic dysregulation by paeoniflorin in osteoarthritic chondrocytes.
Fu C, Lan S, Lin Y, Chen D, Yang Z, Chen C, Chen Y, Yuan Y, Zhong W, Lin Q, Huang Z
Pharmaceutical biology 2026 Dec;64(1):278-294
Pharmaceutical biology 2026 Dec;64(1):278-294
Mechanisms of topical Mahoniae Caulis against acute mastitis: Integrating SMR, network pharmacology, molecular docking, and experimental validation.
Feng S, Zhou N, Wang T, Wang Y, Shu R, Liu Y, Lyu G
Tissue & cell 2026 Aug;101:103472
Tissue & cell 2026 Aug;101:103472
Titanium ion inhibits osteogenic ability of osteoblasts by up-regulating osteoblast Agt gene via macrophages.
Wang MS, Zhou HF, Li H, Gao LN, Feng Y, Zhu H
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2026 Apr;94:127839
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2026 Apr;94:127839
Bacteria-responsive DNAgel system for targeted delivery of photothermally enhanced MXene/MoS(2) in the treatment of pyogenic osteomyelitis.
Jiang Y, Siow L, Xing K, Lin M, Cao Z, Liu Y, Gong J, Zhou S, Gu T, Feng B, Lan R, Gao Y, Yang Y, Zhang C, Lin S, Zhu Z, Leong DT, Yu M
Bioactive materials 2026 Apr;58:123-138
Bioactive materials 2026 Apr;58:123-138
Microglial-Derived Cholesterol 25-Hydroxylase Promotes Epileptic Seizure and Neuroinflammation Mediated by NLRP3 Inflammasome and Lipid Metabolism.
Zhang H, Su T, Wu X, Shi M
Neuroscience bulletin 2026 Apr;42(4):811-826
Neuroscience bulletin 2026 Apr;42(4):811-826
A Dual-Action Nucleoside-Based Supramolecular Hydrogel Combats Periodontitis by Disrupting the Bacteria-Osteoclast Cascade.
Wang Q, Zhao Y, Han L, Li C, Wang Z, Zhang X, Liu T, Wang K, Han X, Xie L, Lai W, Zhao H
Advanced materials (Deerfield Beach, Fla.) 2026 Apr;38(24):e16181
Advanced materials (Deerfield Beach, Fla.) 2026 Apr;38(24):e16181
MicroRNA-493-5p engineered exosomes delivered via piezoelectric microneedles for epigenetic modulation of macrophages in diabetic wound healing.
Chen T, Ouyang L, Mi B, Sheng Y, Al-Smadi F, Xu H, Wu Y, Zhang X, Zhou K, Wu A, Wang X, Liu G, Zhang W
Materials today. Bio 2026 Apr;37:102931
Materials today. Bio 2026 Apr;37:102931
Natural polysaccharide-nucleic acid nanocomplex alleviates myocardial infarction by driving chronologically programmed macrophage polarization.
Guo X, Zhai S, Zhang H, Wang Z, Hu N, Zhang R
Materials today. Bio 2026 Apr;37:102831
Materials today. Bio 2026 Apr;37:102831
Sequential delivery of sinigrin and dabigatran by an in situ self-stabilizing dynamic hydrogel attenuates intervertebral disc degeneration.
Hu R, Liu K, Wang W, Zhang W, Wang L, Zhang Y, Ma H, Cong M, Chi C, Cao J, Zhang B, Liu L, Meng Q, Kong X, Shi B, Li L, Cheng L, Wei Z
Materials today. Bio 2026 Apr;37:102827
Materials today. Bio 2026 Apr;37:102827
Dual-responsive PDA-HP hydrogel enables mitochondria-targeted mild photothermal therapy for spinal cord repair.
Li Y, Hu J, Ran B, Zhong H, Zhong N, Zhong Y, Fu X, Liu X, Wu G, Zhong Q, Li J
Materials today. Bio 2026 Apr;37:102783
Materials today. Bio 2026 Apr;37:102783
Lycium barbarum polysaccharides and/or Bifidobacterium longum exert anti-inflammation and modulate gut microbiota in rats with dextran sulfate sodium-induced ulcerative colitis.
Lee PC, Lian YZ, Nochi T, Chang CC, Lin CF, Huang CC, Chao JC
International journal of biological macromolecules 2026 Apr;358:151699
International journal of biological macromolecules 2026 Apr;358:151699
Macrophage Migratory Inhibitory Factor May Contribute to the Production of Nitric Oxide in Obstructive Sleep Apnea.
Kawachi R, Kobayashi Y, Ooka H, Kanda A, Asako M, Yagi M, Iwai H
Journal of sleep research 2026 Apr;35(2):e70176
Journal of sleep research 2026 Apr;35(2):e70176
Laminarin attenuates neuroinflammation in MPTP-induced Parkinson's disease mouse model via inhibiting dectin-1/Syk/NF-κB signaling.
Zhao RY, Zhang M, Wang XW, Xue F, Zheng YY, Chen WF
Inflammopharmacology 2026 Apr;34(4):2723-2733
Inflammopharmacology 2026 Apr;34(4):2723-2733
Framework nucleic acid-based hydrogel for sequential immune regulation and endogenous TGF-β1 capture in wound healing.
Yin W, Yang Y, Yue Z, Wang R, Bai L, Lin Y, Chen X, Cai X
Biomaterials 2026 Apr;327:123780
Biomaterials 2026 Apr;327:123780
White light-triggered cascade NO/ROS-releasing platform with synergistic antibacterial and angiogenic effects for infected wound healing.
Tao S, Yang M, Fu S, Zhang Z, Mu J, Li T, Jiang X, Chen Y, Wang C, Niu H, Cao P, Liu Y
Acta biomaterialia 2026 Apr;214:465-482
Acta biomaterialia 2026 Apr;214:465-482
Zinc-Containing Bioactive Glass Programs Macrophage Polarization through Extracellular Traps Regulation for Enhanced Diabetic Wound Healing.
Sun R, Wei X, Song Z, Luo J, Ye J, Zhang Y, Zhu L, Gao J, Zhang H, Zhu H, Wang X, Xu K
Advanced healthcare materials 2026 Apr;15(15):e05663
Advanced healthcare materials 2026 Apr;15(15):e05663
Interfacial Bioengineering of Dynamic Networks Hybrid Hydrogel for Programmed Intervention in Oral Precancerous Epithelial States.
Zhao X, Zheng A, Zhao Z, Li Q, Wan T, Deng T, Zhang Y, Cao L, Wu L
Advanced healthcare materials 2026 Apr;15(13):e04229
Advanced healthcare materials 2026 Apr;15(13):e04229
Histochemical characterization of muscularis macrophage loss and disruption of a miR-93-5p-AHNAK neuro-immune axis in Hirschsprung's disease.
Li X, Bu L, Wang X, Li L, Du G, Wu R, Liu W
Histochemistry and cell biology 2026 Apr 3;164(1)
Histochemistry and cell biology 2026 Apr 3;164(1)
Discovery of Imidazo[2,1-b][1,3,4]thiadiazole-Based MNK Inhibitors with Anti-inflammatory Efficacy via Dual Suppression of eIF4E Phosphorylation and NF-κB Signaling.
Li H, Zhuang H, Zhang D, Qiu T, Liu L, Sunyang Z, Han Y, Yu R, Wu G, Yin R, Jiang T
Journal of medicinal chemistry 2026 Apr 23;69(8):9713-9731
Journal of medicinal chemistry 2026 Apr 23;69(8):9713-9731
Triptolide alleviates pathological neovascularisation in oxygen-induced retinopathy via inhibiting the inflammation mediated by NF-κB pathway.
Liu X, Zhao C, Yang H, Huang J, Zhou Q, Zhang Z, Li X, Yang P, Hou S
The British journal of ophthalmology 2026 Apr 22;110(5):527-535
The British journal of ophthalmology 2026 Apr 22;110(5):527-535
Aerobic Exercise Alleviates Oxidative Stress and Inflammation to Attenuate High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease in ApoE(-/-) Mice.
Zhang L, Wang W, Zheng F, Weng J, Lu Y, Li Q, Li T, Li W, Wang L
Metabolites 2026 Apr 21;16(4)
Metabolites 2026 Apr 21;16(4)
Crosstalk Between Clec7a and TLR4 Immune Pathway Drives Renal Damage in a Cisplatin-Induced Acute Kidney Injury Model.
Zhang W, Xue F, Shi X, Fu H, Shi W, Guan C, Xu Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Apr 15;40(7):e71757
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Apr 15;40(7):e71757
Xuming tongmai decoction modulates astrocyte polarization and mitophagy via the PINK1/Parkin pathway in a rat model of acute ischemic stroke.
Ran L, Lan X, Zeng Z, Yu X, Yang R, Tang J
Brain research 2026 Apr 15;1877-1878:150203
Brain research 2026 Apr 15;1877-1878:150203
Kv1.3 regulates macrophage immune function through PI3K/AKT signaling pathway to alleviate metabolic dysfunction-associated steatohepatitis.
Ke T, Zhen WJ, Chen XX, Wang H, Chen S, Tian YY, Wang YT, Zhang L, Wu BM
Journal of molecular medicine (Berlin, Germany) 2026 Apr 11;104(1)
Journal of molecular medicine (Berlin, Germany) 2026 Apr 11;104(1)
Ligustilide Suppresses Macrophage-Mediated Intestinal Inflammation and Restores Gut Barrier via EGR1-ADAM17-TNF-α Pathway in Colitis Mice.
Li Y, Wu Y, Liang J, Chen P, Xu S, Wang Y, Jiang Z, Zhu X, Lin C, Yu Y, Tang H
Research (Washington, D.C.) 2025;8:0864
Research (Washington, D.C.) 2025;8:0864
A Biodegradable Zinc Alloy Membrane with Regulation of Macrophage Polarization for Early Vascularized Bone Regeneration.
Yi L, Tang R, Shao C, Chen C, Tang J, Liao L, Chen L
Biomaterials research 2025;29:0223
Biomaterials research 2025;29:0223
Ginsenoside Rh2-Pretreated Mesenchymal Stem Cell Exosomes Ameliorate Collagen-Induced Arthritis via N6-Methyladenosine Methylation.
Zhou Z, Wu S, Li Y, Shao P, Jiang J
Biomaterials research 2025;29:0220
Biomaterials research 2025;29:0220
The Extracellular Matrix Promotes Diabetic Oral Wound Healing by Modulating the Microenvironment.
Wang Z, Wang L, Wang S, Chen H, Wang D, Li A, Huang Y, Pu Y, Xiong X, Lui X, Huang Y, Guo L
Biomaterials research 2025;29:0169
Biomaterials research 2025;29:0169
HIF-1-mediated macrophage metabolic reprogramming promotes AKI to CKD transition.
Ding H, Zhou Y, Zhu RH, Yu S, Zhang AQ, Liu H, Ji JL, Li ZL
International journal of biological sciences 2025;21(13):5936-5955
International journal of biological sciences 2025;21(13):5936-5955
TNFAIP3 alleviates cerebral ischemia-reperfusion injury by inhibiting M1 microglia polarization via deubiquitination of RACK1.
Bai W, Liu S, Zhou G, Li X, Jiang H, Shao J, Zhu J
PloS one 2025;20(11):e0337601
PloS one 2025;20(11):e0337601
Delivery of miR-26a-5p by Subcutaneous Adipose Tissue-Derived Extracellular Vesicles Alleviates Acute Lung Injury in Mice Through CHUK/NF-κB Pathway.
Xie Y, Ran L, Yue C, Wang C, Chen F, Su Y, Qin Y, Zhang Q, Liu J, Du N, Zhang L, Jiang Y, Liu G
International journal of nanomedicine 2025;20:6001-6021
International journal of nanomedicine 2025;20:6001-6021
Lung Tissue Extracellular Vesicles-Mediated Delivery of miR-128-3p as a Novel Mechanism of Acute Lung Inflammation.
Deng W, Zhu X, Li H, Hu P, Qian K, Liu F
International journal of nanomedicine 2025;20:4831-4848
International journal of nanomedicine 2025;20:4831-4848
Lactate Facilitates Pancreatic Repair Following Acute Pancreatitis by Promoting Reparative Macrophage Polarization.
Jiang J, Wang R, Song P, Peng Q, Jin X, Li B, Ni J, Shen J, Bao J, Wu Z, Ge X, Wang X, Hu G
Cellular and molecular gastroenterology and hepatology 2025;19(9):101535
Cellular and molecular gastroenterology and hepatology 2025;19(9):101535
Tenascin-C Facilitates Microglial Polarization via TLR4/MyD88/NF-κB Pathway Following Subarachnoid Hemorrhage.
Hu ZQ, Ma R, Sun JQ, Peng M, Yuan J, Lai N, Liu J, Xia D
Journal of inflammation research 2025;18:3555-3570
Journal of inflammation research 2025;18:3555-3570
ITGB7 Remodels Inflammation and Immune Microenvironment and Enhances Checkpoint Inhibitor-Based Immunotherapy in Pancreatic Cancer.
Zhu Y, Lei Y, Luo A, Zhang Q, Cai L, Zhang Y, Li X, Wang B, Sun D, Li Y, Sun P, Gong S, Cheng Y
Journal of inflammation research 2025;18:17633-17649
Journal of inflammation research 2025;18:17633-17649
Semaphorin 6D Alleviates Osteoarthritis by Inhibiting NLRP3 Inflammasome Activation and Endoplasmic Reticulum Stress.
Zhang W, Li C, Yao J, Xu Z, Huang Y, Lu Y, Lin X, Guo Z, Zhou X
Journal of inflammation research 2025;18:13909-13924
Journal of inflammation research 2025;18:13909-13924
DNase I alleviates renal inflammatory injury in MRL/lpr mice by inhibiting NETs formation.
Zhang M, Xie X, Da G, Li H, Jin Y
Frontiers in immunology 2025;16:1656069
Frontiers in immunology 2025;16:1656069
Low-dose extracorporeal shock wave attenuates sepsis-related acute lung injury by targeting mitochondrial dysfunction and pyroptosis crosstalk in type II alveolar epithelial cells.
Guo J, Qu X, Ge R, Liu D, Liu J, Hui Q, Ye F, Chen Y, Wang C, Lv D, Tang L, Xia M, Zhang Q
Frontiers in immunology 2025;16:1637378
Frontiers in immunology 2025;16:1637378
miR-223 alleviates DSS-induced colitis by prompting macrophage M2 polarization through PPAR-γ/FOXO1 signaling.
Zhang J, Wang L, Shen Y, Qian X, Wang Z, Wang C
Frontiers in immunology 2025;16:1598781
Frontiers in immunology 2025;16:1598781
Resistance training alleviates muscle atrophy and muscle dysfunction by reducing inflammation and regulating compromised autophagy in aged skeletal muscle.
Cao Y, Zhou J, Quan H, Li W, Li T, Wang L
Frontiers in immunology 2025;16:1597222
Frontiers in immunology 2025;16:1597222
Ginsenoside Re ameliorates thioacetamide-induced acute liver injury through inhibiting autophagy-NLRP3 inflammasome pathway.
Lin J, Wang H, Zhao R, Li S, Chang D, Zheng Y, Zhou X, Huang R, Huang M
Frontiers in pharmacology 2025;16:1592203
Frontiers in pharmacology 2025;16:1592203
Acetylcholine from tuft cells promotes M2 macrophages polarization in Hirschsprung-associated enterocolitis.
Zheng Z, Lin L, Lin H, Zhou J, Wang Z, Wang Y, Chen J, Lai C, Li R, Shen Z, Zhong M, Xie C, Chen Y, Zhang X, Guo Z, Dong R, He S, Chen F
Frontiers in immunology 2025;16:1559966
Frontiers in immunology 2025;16:1559966
Hydrogen sulfide as a therapeutic agent for diabetic wounds: effects on inflammation and fibroblast pyroptosis.
Zhao F, Li Y, Hu Q, Xu J, Zhang N, Chen Y, Jiang X, Gu C, Zhang K, Wu G
Frontiers in immunology 2025;16:1558443
Frontiers in immunology 2025;16:1558443
A multifunctional injectable microsphere with enhanced near-infrared photo-antibacterial, ROS scavenging, and anti-inflammatory properties for periodontitis treatment.
Xiu Z, Zhu Y, Li X, Jiang X, Feng Y, He L, Li C, Cai R, Tao G
Theranostics 2025;15(9):3750-3780
Theranostics 2025;15(9):3750-3780
Hsa_circ_0058495-mediated IGF2BP2 ubiquitination and m6A modification of MEKK1 promote the progression of PDAC.
Lv S, Zhang J, Peng X, Liu H, Chu T, Liu Z, Duan K, Guo J, Wang J, Liu Y, Wei F
Theranostics 2025;15(18):9922-9943
Theranostics 2025;15(18):9922-9943
Bioinspired exosome-SiO(2) nanohybrid therapeutic for rheumatoid arthritis treatment.
Zhu Q, Chen R, Wu X, Zhou Y, Wang Z, Zhang H, Zhu H, Sun L, Shuai Z
Theranostics 2025;15(13):6553-6571
Theranostics 2025;15(13):6553-6571
The Effects of M2 Macrophages-Derived Exosomes on Urethral Fibrosis and Stricture in Scar Formation.
Ren X, Wang Z, Wang J, Li X, Wei H, Liu C, Liu S, Zhu Y, Feng C, Yin Y, Tian Y, Wu M, Zeng X
ImmunoTargets and therapy 2025;14:151-173
ImmunoTargets and therapy 2025;14:151-173
A multifunctional dihydromyricetin-loaded hydrogel for the sequential modulation of diabetic wound healing and glycemic control.
Li H, Wen H, Zhang H, Cao X, Li L, Hu X, Zhang Y, Shen X, Shubhra QTH, Yang H, Cai X
Burns & trauma 2025;13:tkaf024
Burns & trauma 2025;13:tkaf024
The effect of ponicidin on CFA-induced chronic inflammatory pain and its mechanism based on network pharmacology and molecular docking.
Wang P, Jiang H, Yao J, He G, Tao T, Qin Z
Frontiers in medicine 2025;12:1510271
Frontiers in medicine 2025;12:1510271
Leukemia Inhibitory Factor via JAK-STAT Signaling Drives Beryllium Sulfate-Induced Epithelial-Mesenchymal Transition in 16HBE Cells.
Li Y, Sun Z, Tong Y, Yan C, Huang L, Zhang Z
Journal of applied toxicology : JAT 2025 Sep;45(9):1720-1729
Journal of applied toxicology : JAT 2025 Sep;45(9):1720-1729
Chronic Pod-Mod E-Cigarette Aerosol Exposure Induces Aortic Dysfunction in Hypercholesterolemic Mice: Role of Oxidative Stress and Inflammation.
Farra YM, Sabnis S, Matz J, Wilker HIB, Williams VA, Trejo O, Kim H, Rivera CF, Vlahos J, Ramkhelawon B, Oakes JM, Bellini C
Arteriosclerosis, thrombosis, and vascular biology 2025 Sep;45(9):1574-1592
Arteriosclerosis, thrombosis, and vascular biology 2025 Sep;45(9):1574-1592
Extraction, separation, structure identification and anti-inflammatory activity of polysaccharides from Lamiophlomis Rotata.
Jiang Q, Hu M, Li X, Zhang Q, Zhang X, Jiang M
International journal of biological macromolecules 2025 Sep;322(Pt 4):146943
International journal of biological macromolecules 2025 Sep;322(Pt 4):146943
TBX21 knockdown attenuates neuroinflammation induced by intracerebral hemorrhage via the SIRT1-WDR5-H3K4me3 axis.
Zou Z, Liu Z, Zhang Z, Li X
Brain research bulletin 2025 Sep;229:111415
Brain research bulletin 2025 Sep;229:111415
Flavonoids from the stems of Ammopiptanthus nanus and their in vitro and in vivo anti-inflammatory activities.
Zhang R, Yang Q, Sun Y, Zhang H, Zhang J, Lu X, Satiwald M, Zhang P, Jin Y, Ji J, Chen L
Fitoterapia 2025 Sep;185:106678
Fitoterapia 2025 Sep;185:106678
Piezoelectric-IL-4 programmed regulation of immuno-microenvironment-induced mesenchymal stem cell recruitment and differentiation for bone regeneration.
Zhang J, Wang W, Wang M, Hai H, Li K, Wang L, Lei M, Cui L, Liu H, Guo J, Liu C
Ultrasonics sonochemistry 2025 Sep;120:107431
Ultrasonics sonochemistry 2025 Sep;120:107431
Modulating Macrophage-Nucleus Pulposus Cell Crosstalk via Sequential Drug Delivery Attenuates Disc Degeneration.
Kong X, Hu R, Zhang P, Li Q, Song K, Gu H, Zheng J, Liu S, Liu L, Jin L, Cheng L, Li C, Wei Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(36):e07178
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(36):e07178
A Myelin Debris Cleaner for Spinal Cord Injury Recovery: Polycaprolactone / Cell Membrane Assembled Scaffolds.
Zhou Y, Xu T, Zhou Y, Chen N, Wu Z, Yang Z, Yang C, Chen X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(36):e03269
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(36):e03269
Inhibition of Dectin-1 alleviates inflammation in early diabetic retinopathy by regulating microglia phenotype.
Sang W, Zhang X, Hu Q, Jiang B, Guan J, Huang Z, Sun L, Sun D
Gene 2025 Sep 5;963:149572
Gene 2025 Sep 5;963:149572
METTL14 knockdown augmented the polarization of M2-like macrophages to promote acute myeloid leukemia progression.
Wang M, Xie Z, Tan Y, Zhou Y, Wang S, Zhang P, Li J
Human cell 2025 Sep 30;38(6):168
Human cell 2025 Sep 30;38(6):168
Isoacteoside alleviates LPS-induced depressive-like behaviors in mice by inhibiting neuroinflammation through regulating microglial polarization and oxidative stress.
Bi J, Zhang H, Wei J, Huang X, Dong Y, Dong Y, Xie Y, Li R, Chen S, Zhao Z, Cheng B
Behavioral and brain functions : BBF 2025 Sep 29;21(1):30
Behavioral and brain functions : BBF 2025 Sep 29;21(1):30
Proinflammatory polarization of adipose tissue macrophages in cows with subclinical ketosis constitutes a critical driver of adipose tissue remodeling and inflammation.
Zhao B, Li M, Zhang H, Chang R, Wang J, Zhao W, Yang Y, Usman M, Loor JJ, Xu C
Journal of animal science and biotechnology 2025 Sep 29;16(1):130
Journal of animal science and biotechnology 2025 Sep 29;16(1):130
Piceatannol improves autoimmune hepatitis by inhibiting the immune activities of T cells and macrophages through binding with c-Jun.
Xu C, Lu C, Wang W, Wang Z, Qiu Y, Han M, Yang J, Li S
Immunologic research 2025 Sep 27;73(1):137
Immunologic research 2025 Sep 27;73(1):137
Effect of Oral Peritumoral Tissue on Infiltration and Differentiation of Tumor-Associated Macrophages in Oral Squamous Cell Carcinoma.
Piao T, Takabatake K, Arashima T, Zhao Y, Kawai H, Eain HS, Soe Y, Min ZZ, Nakano K, Nagatsuka H
Cells 2025 Sep 22;14(18)
Cells 2025 Sep 22;14(18)
Artesunate suppresses ocular inflammation in endotoxin-induced uveitis through inhibiting the NF-κB signaling pathway and M1 macrophage polarization.
Liu L, Hao X, Lu B, Li X, Xie L
European journal of pharmacology 2025 Sep 15;1003:177947
European journal of pharmacology 2025 Sep 15;1003:177947
Curcumin inhibits aortic dissection progression: Insights from the integrated analysis of network pharmacology, gut microbiota, and serum metabolomics.
Liu S, Cheng S, Shan J, Xia L, Li Z
Biochemical and biophysical research communications 2025 Sep 1;777:152281
Biochemical and biophysical research communications 2025 Sep 1;777:152281
Polyphyllin I enhances the anti-tumor efficacy of Palbociclib by reversing M2 macrophage polarization in lung cancer.
Jiang Y, Wang L, Chen Y, Li Y, Chen G, Lu Y, Jiang C, Chai K, Wang Y
Biochemical and biophysical research communications 2025 Sep 1;777:152228
Biochemical and biophysical research communications 2025 Sep 1;777:152228
Melatonin Prevents the Progression of MASLD via Inhibiting FFAs-Induced Ferroptosis through KEAP1/NRF2/HO-1 Pathway.
Li S, Rao P, Yu W, Tang Y, Jiang X, Liu J
Biomolecules & therapeutics 2025 Sep 1;33(5):876-889
Biomolecules & therapeutics 2025 Sep 1;33(5):876-889
Therapeutic targeting of Nrf2/HO-1/NF-κB signaling axis with casticin mitigates intervertebral disc degeneration: in vitro and in vivo investigations.
Wu L, Wang Z, Wu Z, Wu Y
In vitro cellular & developmental biology. Animal 2025 Oct;61(9):1120-1136
In vitro cellular & developmental biology. Animal 2025 Oct;61(9):1120-1136
On-Demand ER Stress Modulation in Tumor Cells and TAMs via an Adaptively Transformable Nanoplatform Enhances Photodynamic Immunotherapy.
Zhao B, Chen X, Xu S, Xing Y, Shao J, Xiao Y, Qi J, Qian H, Huang D, Chen W, Zhong Y
Advanced materials (Deerfield Beach, Fla.) 2025 Oct;37(42):e07299
Advanced materials (Deerfield Beach, Fla.) 2025 Oct;37(42):e07299
Synergistic exacerbation of periprosthetic osteolysis by inflammatory bowel disease and titanium ions: Impaired osteogenesis of BMSCs via PI3K/AKT signaling.
Ming P, Li K, Zhu W
Materials today. Bio 2025 Oct;34:102236
Materials today. Bio 2025 Oct;34:102236
Self-assembled extracellular matrix-lipid nanoparticle composite for site-specific siRNA delivery to improve cardiac repair post-myocardial infarction.
Wang X, Zhong Y, Qian B, Huang S, Long Q, Zhang H, Zhao Q, Ye X
Materials today. Bio 2025 Oct;34:102205
Materials today. Bio 2025 Oct;34:102205
Chiral gold nanoparticles manipulate osteoimmune microenvironment via macrophage autophagy for bone regeneration.
Wang J, Gao N, Wei J, Liao L
Materials today. Bio 2025 Oct;34:102131
Materials today. Bio 2025 Oct;34:102131
Magnoflorine ameliorates cartilage degradation in osteoarthritis through inhibition of mitochondrial reactive oxygen species-mediated activation of the NLRP3 inflammasome.
Peng Y, Huang YH, Luo X, Li MC, Xiao QQ, Qiu L, Fu Q
Journal of Asian natural products research 2025 Oct;27(10):1528-1549
Journal of Asian natural products research 2025 Oct;27(10):1528-1549
TSP50 in Neural Stem Cells Regulates Aging-Related Cognitive Decline and Neuroinflammation by Altering the Gut Microbiota.
Li X, Chen Y, Gao Z, Liu X, Song Z, Gao F, Wang S, Yu C, Sun L, Huang Y, Zheng L, Wang G, Sun Y, Li J, Yang X, Bao Y
Aging cell 2025 Oct;24(10):e70188
Aging cell 2025 Oct;24(10):e70188
Oligodendrocyte-specific knockout of FPN1 affects CNS myelination defects and depression-like behavior in mice.
Zhang N, Zhang S, Liu X, Zuo YY, Cui YG, Wang F, Zhang JH, Chang YZ, Yu P
Free radical biology & medicine 2025 Oct;238:370-386
Free radical biology & medicine 2025 Oct;238:370-386
Injectable Immune-Regulating Mesenchymal Stem Cells Hydrogel for Localized Scleroderma Treatment.
Liu R, Kong B, Lu J, Zhao Y, Sun L
ACS nano 2025 Oct 7;19(39):34785-34796
ACS nano 2025 Oct 7;19(39):34785-34796
Implantable drug delivery systems with a bioinspired zwitterionic nanocoating resist foreign body reaction-induced obstruction and enable sustained delivery.
Cai H, Chen A, You Y, Qu J, Scheper V, Tang J, Zhang H
Biomaterials science 2025 Oct 7;13(20):5837-5850
Biomaterials science 2025 Oct 7;13(20):5837-5850
Cardiotoxic Effect Induced by F-53B via Nitric Oxide Signalling on Parkin(-/-) Mice.
Nie J, Hu C, Huang Y, Ma Y, Lu L
Toxics 2025 Oct 31;13(11)
Toxics 2025 Oct 31;13(11)
Intratumoral microbiota-driven macrophage reprogramming in pancreatic cancer via Blautia metabolite 6-hydroxyhexanoic acid.
Zhong Y, Zhang D, Ding F, Zhang H, Guo Y, Huang Q, Liu G, Zhang X, Weng S
International immunopharmacology 2025 Oct 30;164:115421
International immunopharmacology 2025 Oct 30;164:115421
Dental pulp stem cells promote the recovery of spinal cord injury by regulating microglia polarization via JAK2/STAT3 signaling pathway.
Yang T, Tang S, Feng W, Li Z, Liu X, Cheng C, Wei F, Ding G
International immunopharmacology 2025 Oct 30;164:115395
International immunopharmacology 2025 Oct 30;164:115395
Arginyl-fructosyl-glucose (AFG), a major Maillard reaction product of red ginseng, improved kidney and pancreatic injury in vitro and in vivo in type 2 diabetes mellitus.
Tsopmejio ISN, Tang S, Gao XF, Liu Z, Li XD, Qi MH, Zhu HY, Wang Z, Li W
International immunopharmacology 2025 Oct 30;164:115378
International immunopharmacology 2025 Oct 30;164:115378
MBD2 deficiency attenuates CCl(4)-induced hepatic fibrosis by inhibiting M2 macrophage polarization.
Yu W, Li R, Wang Y, Wang YN, Huang Y, Zhang Y, Nie H, Liu L, Chen H, Zheng B, Gong Q
International immunopharmacology 2025 Oct 30;164:115306
International immunopharmacology 2025 Oct 30;164:115306
Microwave therapy promotes wound healing in diabetic mice by activating IL-33/ST2-mediated M2 macrophage polarization.
He M, Huang X, Liu T, Yang Q, Zheng Y, Wu Y, Zhang Y, Liang Y, Liao Z, Peng S, Yin H, He R
Scientific reports 2025 Oct 30;15(1):37984
Scientific reports 2025 Oct 30;15(1):37984
Protective Effect of Mesaconate on Autoimmune Hepatitis via Suppression of Inflammatory Response and Oxidative Stress.
Zhang Q, Wang J, He Y, Zhang K, Hong W, Han T
Journal of clinical and translational hepatology 2025 Oct 28;13(10):847-856
Journal of clinical and translational hepatology 2025 Oct 28;13(10):847-856
Galangin Alleviates Intervertebral Disc Degeneration via the Nrf2/NF-κB Pathway.
Chen L, Ying S, Guo Z, Tan H, Jin Y, Wang X, Sun J, Zhang X, Zhou C, Chen D, Jiang Y, Peng K
Journal of agricultural and food chemistry 2025 Oct 15;73(41):26060-26072
Journal of agricultural and food chemistry 2025 Oct 15;73(41):26060-26072
CXCL10 modulates airway inflammation in asthma via Sirt3-dependent macrophage homeostasis.
Ding W, Wang P, Ding Z, Yang B, Huo S, Lin P, Zhao J, Xu Y, Ding S
Life sciences 2025 Oct 15;379:123849
Life sciences 2025 Oct 15;379:123849
Research on the Protective Effects and Mechanisms of Gallic Acid Against Cognitive Impairment Induced by Chronic Sleep Deprivation.
Zhang X, Cui J, Sun J, Wang F, Fan B, Lu C
Nutrients 2025 Oct 12;17(20)
Nutrients 2025 Oct 12;17(20)
Dysregulated Protein s-Nitrosylation Promotes Nitrosative Stress and Disease Progression in Heart Failure With Preserved Ejection Fraction.
Li Z, LaPenna KB, Gehred ND, Yu X, Tang WHW, Doiron JE, Xia H, Chen J, Driver IH, Sachse FB, Muraoka N, Katsouda A, Zampas P, Haydel AG, Quiriarte H, Allerton TD, Zagouras A, Wilcox J, Gromova T, Zheng Y, Papapetropoulos A, Shah SJ, Goodchild TT, Jensen MB, Sharp TE 3rd, Vondriska TM, Lefer DJ
Circulation research 2025 Oct 10;137(9):1185-1206
Circulation research 2025 Oct 10;137(9):1185-1206
Nitric oxide regulates spindle dynamics to modulate the maturation of goat oocytes.
Xu R, Zheng Z, Bai W, Liu M, Lu S, Peng S, Pan M, Ma B
Theriogenology 2025 Oct 1;245:117517
Theriogenology 2025 Oct 1;245:117517
Knockdown of USP22 alleviates LPS-induced microglial inflammation and mouse depressive-like behaviors via KAT2A.
Lu Y, Zheng Y, Sun X, Song Y, Zhou Y, Shen F, Huang R, Xu Z
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2025 Nov;50(12):1904-1912
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2025 Nov;50(12):1904-1912
NPB-1575 attenuates neuroinflammation and resists ferroptosis in rat ischemic stroke via IRS2 signaling pathway.
Li XN, Shang NY, Liu MY, Sui SY, Tang JS, Lan JQ, Kang YY, Zhang BD, Wen ZP, Feng XH, Wu L, Dai JG, Peng Y
Acta pharmacologica Sinica 2025 Nov;46(11):2893-2907
Acta pharmacologica Sinica 2025 Nov;46(11):2893-2907
Innovative DNA tetrahedron inspired by ancient mortise-and-tenon technique offers new immunotherapy strategy for metastatic breast cancer.
Zhang N, Qian L, Xu C, Duan F, Ma Y, Zhou L, Zhang Y, Ma Y, Lin Q, Lu K
Biomaterials 2025 Nov;322:123390
Biomaterials 2025 Nov;322:123390
Interleukin-10 Modified Human Mesenchymal Stromal Cells Markedly Alleviated Periodontitis by Inducing Macrophage M2 Polarisation.
Heinayati A, Jiang X, Gao T, Wang L, Wang B, Qin H
Journal of cellular and molecular medicine 2025 Nov;29(21):e70934
Journal of cellular and molecular medicine 2025 Nov;29(21):e70934
MSC-derived small extracellular vesicles attenuate diabetic retinopathy through miR-29a-3p regulated microglia M1-like polarization.
Tong J, Chen Y, Zhang Y, Liu C, He C, Liu Y, Liao Y, Chen F, Yao G, Xie Z
Experimental eye research 2025 Nov;260:110586
Experimental eye research 2025 Nov;260:110586
Exosomal CagA induces macrophage polarization and ferroptosis by JAK1-2/STAT1 signaling pathway in Helicobacter pylori-associated gastritis.
Lin J, Lu W, Cheng S, Zhang Z, Hu Y, Chen S, Li H, Chi J, Liu X, Guo Y, Xu C
Free radical biology & medicine 2025 Nov;239:91-103
Free radical biology & medicine 2025 Nov;239:91-103
Treadmill exercise alleviates STING-mediated microglia pyroptosis and polarization via activating mitophagy post-TBI.
Chen J, Zhu T, Yang X, Yang Z, Shen M, Gu B, Wang D, Zhang Y, Zhang M, Sun S, Yu J, Yan C
Free radical biology & medicine 2025 Nov;239:155-176
Free radical biology & medicine 2025 Nov;239:155-176
AMPK upregulates SOCS1 to promote TFEB nuclear transfer, enhances autophagy, inhibits macrophage M1 polarization and relieves acute lung injury.
Nie W, Gong C, Liu Y, Yang J, Dai Q, Liao Y, Li F
Molecular immunology 2025 Nov;187:240-253
Molecular immunology 2025 Nov;187:240-253
RRBP1 Inhibition Reduces Microglial M1 Polarization and Inflammation-Mediated Neuronal Loss and Oxidative Stress by Regulating ERK Pathway in Alzheimer's Disease.
Li Y, Fan H, Han X, Ni M, Hou X, Xia H, Shi Y, Zhang L, Sun J
Molecular neurobiology 2025 Nov 6;63(1):5
Molecular neurobiology 2025 Nov 6;63(1):5
Hepatic acetyl-CoA metabolism modulates neuroinflammation and depression susceptibility via acetate.
Cao Y, Zhao Y, Deng T, Zhou Q, Hu G, Hu ZL, Jiang YY, Yang XH, Wang F, Wu PF, Chen JG
Cell metabolism 2025 Nov 4;37(11):2185-2201.e8
Cell metabolism 2025 Nov 4;37(11):2185-2201.e8
Quercetin as a Novel Antidepressant: Mechanistic Insights into Its Neuroprotective and Anti-inflammatory Effects.
Fan X, Wang Z, Sun L, Qin Y, Liu Y, Wu S, Du L
Molecular neurobiology 2025 Nov 24;63(1):155
Molecular neurobiology 2025 Nov 24;63(1):155
The miR-125a-5p/IRF4 Axis Mediates Sodium Arsenite-Induced M2 Macrophage Polarization.
Yu Y, Yao F, Tong S, Li M, Liao Q, Wang F, Xi S
Biomolecules 2025 Nov 20;15(11)
Biomolecules 2025 Nov 20;15(11)
Salidroside-Pretreated Small Extracellular Vesicles Derived from Human Umbilical Cord Mesenchymal Stem Cells Promote Blood-Spinal Cord Barrier Repair After Spinal Cord Injury in Mice.
Wang J, Zhu Q, Chan P, Zhu Z, Zheng M, Mao Z, Gu M, Ren Z, Cui M, Liu J, Zhang Y
Molecular neurobiology 2025 Nov 19;63(1):89
Molecular neurobiology 2025 Nov 19;63(1):89
Omentin-1 reduced synovial M1 macrophages through SIRT6 signaling pathway and alleviated knee osteoarthritis response in mice.
Wu H, Sun W, Zhang Q, Cheng G, Cao Z
Arthritis research & therapy 2025 Nov 18;27(1):216
Arthritis research & therapy 2025 Nov 18;27(1):216
TIM3 attenuates morphine antinociceptive tolerance and microglial neuroinflammation by suppressing the TRAF6/NF-κB pathway in male mice.
Yang H, Shen T, Qi Z, Yang Z, Zhang M, Jiang J, Sun Z, Lu C
Neuropharmacology 2025 Nov 15;279:110638
Neuropharmacology 2025 Nov 15;279:110638
Treatment of Parkinson's Disease with an Anti-Inflammasome NLRP3 Inhibitor Derived from a Natural Product.
Li W, Zhang J, Chen Q, Luo B, Zhou B, Wang J, Yang Y, Liu Y, Wen S, Kong DX, Chen J, Wei S, Duez P, Sharipov A, Li Y, Hu X
ACS pharmacology & translational science 2025 Nov 14;8(11):3896-3909
ACS pharmacology & translational science 2025 Nov 14;8(11):3896-3909
Single-atom Ca nanozyme induces glioma death through Ca(2+)-overload-enhanced catalytic tumor nanotherapy, ferroptosis and synergistic remodeling of the immune microenvironment.
Jin Z, Li X, Hou X, Hu J, Zhuo Y, Shi J, Xu T, Zhao Q, Jing Z
Journal of nanobiotechnology 2025 Nov 13;23(1):716
Journal of nanobiotechnology 2025 Nov 13;23(1):716
Wuling San ameliorates cerebral ischemia-reperfusion injury via suppression of the TRPM2/NLRP3 pathway.
Li H, Tao D, Chen Y, Deng Y, Wei W, Xue X
European journal of medical research 2025 Nov 10;30(1):1096
European journal of medical research 2025 Nov 10;30(1):1096
Application of Dental Pulp Stem Cell-Derived Intracellular Vesicles for Diabetic Wound Healing.
Pang P, Liu Y, Song H, Ye Z, Zhou H, Zhang R, Kumeria T, She W, Xu C, Mei PL, He Y, Ye Q
Diabetes 2025 Nov 1;74(11):2060-2074
Diabetes 2025 Nov 1;74(11):2060-2074
Paraquat induced neuro-immunotoxicity: Dysregulated microglial antigen processing and mitochondrial activated mechanisms.
Shi G, Wang K, Liu Q, Wu C, Zhang Q, Ma Y, Qi A, Huang M
Chemico-biological interactions 2025 Nov 1;421:111721
Chemico-biological interactions 2025 Nov 1;421:111721
Ultrasound-triggered injectable piezoelectric nanocomposite hyaluronic acid-based hydrogel for modulating inflammation and chondrogenesis in osteoarthritis treatment.
Lin J, Li S, Peng Y, Qiu C, Yang M, Guo J, Yu B, Chen Y
Carbohydrate polymers 2025 Nov 1;367:123909
Carbohydrate polymers 2025 Nov 1;367:123909
Remote ischemic conditioning as a potential therapy for Parkinson's Disease: Inhibiting TLR4-Driven neuroinflammation and oxidative damage.
Cai L, Ding Y, Tekreeti AA, Li F, Zhu Y, Geng X, Ji X
Brain research 2025 Nov 1;1866:149920
Brain research 2025 Nov 1;1866:149920
Icariin modulates the tumor microenvironment in colorectal cancer by targeting M2 macrophage polarization via PI3K/AKT pathway.
Chen Y, Qi Y, Jiang Y, Li Y, Yang S, Wang L, Li M, Chai K, Wang Y
Bioorganic & medicinal chemistry 2025 Nov 1;129:118317
Bioorganic & medicinal chemistry 2025 Nov 1;129:118317
Th22 cells promote the transition from homeostatic to reactive microglia in diabetic encephalopathy.
Yu SX, Yu HD, Wang YF, Yao TF, Lv SZ, Wang YC, Li JQ, Liu WQ, Ding JY, Liu XZ, Zuo ZF, Liu WP
Acta diabetologica 2025 May;62(5):633-650
Acta diabetologica 2025 May;62(5):633-650
Platelet activation stimulates macrophages to enhance ulcerative colitis through PF4/CXCR3 signaling.
Niu Y, Li A, Xu W, Zhang R, Mei R, Zhang L, Zhou F, Pan Q, Yan Y
International journal of molecular medicine 2025 May;55(5)
International journal of molecular medicine 2025 May;55(5)
Early Potentially Irreversible Cardiac Damage in Fabry Disease Precedes Gb3 Inclusion Body Formation.
Lee CL, Chen PS, Lu YY, Chiang YT, Yen CT, Huang CY, Cheng YF, Lin HY, Chen YR, Niu DM
The Canadian journal of cardiology 2025 May;41(5):939-951
The Canadian journal of cardiology 2025 May;41(5):939-951
Nose-to-Brain Delivery of Circular RNA SCMH1-Loaded Lipid Nanoparticles for Ischemic Stroke Therapy.
Jia Y, Xu L, Leng S, Sun Y, Huang X, Wang Y, Ren H, Li G, Bai Y, Zhang Z, Han B, Shen L, Ju M, Chen L, Yao H
Advanced materials (Deerfield Beach, Fla.) 2025 May;37(19):e2500598
Advanced materials (Deerfield Beach, Fla.) 2025 May;37(19):e2500598
Regulation of Nrf2/GPX4 Signaling Pathway by Hyperbaric Oxygen Protects Against Depressive Behavior and Cognitive Impairment in a Spinal Cord Injury Rat Model.
Li C, Wu Z, Chen F, Dai C, Yang X, Ye S, Shi M, Chen P, Liu X, Liu F
CNS neuroscience & therapeutics 2025 May;31(5):e70421
CNS neuroscience & therapeutics 2025 May;31(5):e70421
Flammulina velutipes polysaccharide exerts immunomodulatory function involving RSAD2 to regulate the NF-κB/MAPK signaling pathway in RAW264.7 macrophage cells and in mouse spleen cells.
Wang Q, Wang S, Cui L, Zhang Y, Waterhouse GIN, Sun-Waterhouse D, Ma C, Kang W
International journal of biological macromolecules 2025 May;309(Pt 3):142985
International journal of biological macromolecules 2025 May;309(Pt 3):142985
Temporal and spatial expression of Phosphodiesterase-4B after sciatic nerve compression in rats and its mechanism of action on sciatic nerve repair.
Wang Y, Zhou Y, Liu J, Liu C, Li Z, Sun X
Neurochemistry international 2025 May;185:105940
Neurochemistry international 2025 May;185:105940
Biodegradable Piezoelectric Janus Membrane with Enhanced Antibacterial and Osteoinductive Properties for Periodontitis Therapy.
Cheng J, Wu L, Fu H, Hu L, Wang W, Heng BC, Zhang X, Liu O, Deng X, Liu Y
Advanced healthcare materials 2025 May;14(12):e2500543
Advanced healthcare materials 2025 May;14(12):e2500543
Dectin-1 participates in neuroinflammation and dopaminergic neurodegeneration through synergistic signaling crosstalk with TLR4.
Xue F, Zhang M, Zhao RY, Wang XW, Gu Y, Yang Y, Chen WF
Brain, behavior, and immunity 2025 May;126:260-273
Brain, behavior, and immunity 2025 May;126:260-273
MiR-29a-3p ameliorate behavioral deficiency in hypoxia-ischemia brain damage in neonatal mice by inhibiting BTG2.
Luo Q, Xing X, Song Y, Gu B, Hu Q, Liu W, Xiao Y, Wang Z
Behavioural brain research 2025 May 28;486:115552
Behavioural brain research 2025 May 28;486:115552
Comparative efficacy of preventive vs. therapeutic resveratrol in modulating gut microbiota and alleviating inflammation in DSS-induced colitis.
Qin S, Yang Z, Lei J, Xie Q, Jiang L, Fan Y, Luo Y, Wei K, Luo W, Yu B
BMC immunology 2025 May 28;26(1):42
BMC immunology 2025 May 28;26(1):42
Therapeutic potential of ADSC-derived exosomes in acute lung injury by regulating macrophage polarization through IRF7/NLRP3 signaling.
Ren J, Lei G, Dong A, Cao S, Han X, Li H
International immunopharmacology 2025 May 27;156:114658
International immunopharmacology 2025 May 27;156:114658
Polygonum multiflorum Inhibits Pulmonary Inflammation and Fibrosis in PM(2.5)-Induced Dysfunction Through the Regulation of the TLR4/TGF-β1 Signaling Pathway in Mice.
Choi HJ, Lee HL, Kim IY, Heo HJ
International journal of molecular sciences 2025 May 25;26(11)
International journal of molecular sciences 2025 May 25;26(11)
Comparison of the Immunomodulatory Roles of Porcine Milk-Derived Extracellular Vesicles from Different Stages of Lactation.
Wang H, Wang Y, Ling M, Wang S, Luo J, Sun J, Xi Q, Chen T, Zhang Y
Journal of agricultural and food chemistry 2025 May 21;73(20):12247-12260
Journal of agricultural and food chemistry 2025 May 21;73(20):12247-12260
Inhibiting cathepsin B alleviates acute lung injury caused by sepsis through suppression of pyroptosis in lung epithelial cells.
Zhang X, Deng Z, Zhang X, Xu Q, Liu L, Yang D, Guo Z
European journal of medical research 2025 May 20;30(1):403
European journal of medical research 2025 May 20;30(1):403
Single-cell sequencing reveals alterations in the ovarian immune microenvironment regulated by 17β-estradiol in neonatal mice.
Yan YT, Li YX, Meng YT, Li Q, Zhao XE, Wei Q, Pan MH, Peng S, Ma BH
Zoological research 2025 May 18;46(3):618-633
Zoological research 2025 May 18;46(3):618-633
Astragaloside IV prevents liver fibrosis by blocking glycolysis-mediated macrophage M1 polarization.
Hu Y, Kuang M, Song H, Tan Y, Zhou F, Pei G, Jiao L
European journal of pharmacology 2025 May 15;995:177353
European journal of pharmacology 2025 May 15;995:177353
Neuroprotective, Antioxidant and Anti-Inflammatory Effect of Greek Pomegranate Seed Oil on N2a Neuroblastoma Cells and Mild Cognitive Impairment Patients.
Tzekaki EE, Katsipis G, Chatzikostopoulos A, Koutoupa A, Lavrentiadou SN, Tsolaki M, Pantazaki AA
Biology 2025 May 15;14(5)
Biology 2025 May 15;14(5)
IGF2BP3-mediated m(6)A modification of RASGRF1 promoting joint injury in rheumatoid arthritis.
Geng Q, Jiao Y, Diao W, Xu J, Wang Z, Wang X, Wang Z, Zhao L, Yang L, Wang Y, Deng T, Wang B, Xiao C
Bone research 2025 May 12;13(1):51
Bone research 2025 May 12;13(1):51
Allocryptopine Attenuates Inflammatory Responses in Microglial Cells Via TLR4-Dependent NF-κB and p38 MAPK Pathways.
Nigdelioglu Dolanbay S, Şirin S, Aslim B
Molecular neurobiology 2025 Mar;62(3):3833-3847
Molecular neurobiology 2025 Mar;62(3):3833-3847
Trimethylamine N-oxide aggravates human aortic valve interstitial cell inflammation by regulating the macrophages polarization through a N6-methyladenosine-mediated pathway.
Wen L, Lin X, Hu D, Li J, Xie K, Li S, Su S, Duan X, Zhong G, Lin Y, Chen Y, Xu T, Zeng Q
Atherosclerosis 2025 Mar;402:119109
Atherosclerosis 2025 Mar;402:119109
Multifunctional sericin-based biomineralized nanoplatforms with immunomodulatory and angio/osteo-genic activity for accelerated bone regeneration in periodontitis.
Ming P, Li B, Li Q, Yuan L, Jiang X, Liu Y, Cai R, Zhou P, Lan X, Tao G, Xiao J
Biomaterials 2025 Mar;314:122885
Biomaterials 2025 Mar;314:122885
Synergistic therapeutic effect of parecoxib and ilomastat combination in osteoarthritis via inhibition of IL-17/PI3K/AKT/NF-κB activity.
Feng X, Ma Y, Zhao Y, Zhao Z, Song Z, Lin L, Wang W
Molecular immunology 2025 Mar;179:94-105
Molecular immunology 2025 Mar;179:94-105
Colon-Targeted Ginseng Polysaccharides-Based Microspheres for Improving Ulcerative Colitis via Anti-Inflammation and Gut Microbiota Modulation.
Huo DY, Li YF, Song LJ, Zhang WX, Li XD, Zhang J, Ren S, Wang Z, Li W
Advanced healthcare materials 2025 Mar;14(6):e2404122
Advanced healthcare materials 2025 Mar;14(6):e2404122
Genetically Programmed Single-Component Protein Hydrogel for Spinal Cord Injury Repair.
Wei Y, Zhou X, Li Z, Liu Q, Ding H, Zhou Y, Yin RF, Zheng L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(10):e2405054
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(10):e2405054
M1 polarization of hepatic macrophages in cows with subclinical ketosis is an important cause of liver injury.
Zhao B, Li M, Zhang H, Wang J, Zhao W, Yang Y, Usman M, Loor JJ, Xu C
Journal of dairy science 2025 Mar;108(3):2933-2946
Journal of dairy science 2025 Mar;108(3):2933-2946
Erianin alleviates autoimmune myocarditis by suppressing the M1 polarization of macrophages via the NF-κB/NLRP3 signaling pathway.
Liu W, Mao Y, Li H, Hu J, Gan T, Wang Y, Wang Y, Wang Z
European journal of pharmacology 2025 Mar 5;990:177292
European journal of pharmacology 2025 Mar 5;990:177292
Indole-3-Propionic Acid Attenuates Neuroinflammation and Cognitive Deficits by Inhibiting the RAGE-JAK2-STAT3 Signaling Pathway.
Hao Z, Ji R, Su Y, Wang H, Yang W, Zhang S, Liu Y, Ma S, Guan F, Cui Y
Journal of agricultural and food chemistry 2025 Mar 5;73(9):5208-5222
Journal of agricultural and food chemistry 2025 Mar 5;73(9):5208-5222
Sinomenine alleviates neuroinflammation in chronic cerebral hypoperfusion by promoting M2 microglial polarization and inhibiting neuronal pyroptosis via exosomal miRNA-223-3p.
Yang Q, Chen Q, Zhang KB, Liu Y, Zheng JC, Hu DX, Luo J
Acta neuropathologica communications 2025 Mar 5;13(1):48
Acta neuropathologica communications 2025 Mar 5;13(1):48
Novel regulation mechanism of histone methyltransferase SMYD5 in rheumatoid arthritis.
Xiao C, Su Z, Zhao J, Tan S, He M, Li Y, Liu J, Xu J, Hu Y, Li Z, Fan C, Liu X
Cellular & molecular biology letters 2025 Mar 31;30(1):38
Cellular & molecular biology letters 2025 Mar 31;30(1):38
Tremella polysaccharide microneedles loaded with magnetic dental pulp stem cell intracellular vesicles used for androgenic alopecia.
Liu Y, Zhou H, Pang P, Liu Y, Situ J, Wang J, He Y, Ye Q
Stem cell research & therapy 2025 Mar 31;16(1):161
Stem cell research & therapy 2025 Mar 31;16(1):161
Berberine Exerts Neuroprotective Effects in Alzheimer's Disease by Switching Microglia M1/M2 Polarization Through PI3K-AKT Signaling.
Hu Y, Zhang P, Wang X
Physiological research 2025 Mar 24;74(1):129-140
Physiological research 2025 Mar 24;74(1):129-140
Anti-TNFα and Anti-IL-1β Monoclonal Antibodies Preserve BV-2 Microglial Homeostasis Under Hypoxia by Mitigating Inflammatory Reactivity and ATF4/MAPK-Mediated Apoptosis.
Zhang L, Guan C, Wang S, Pfeiffer N, Grus FH
Antioxidants (Basel, Switzerland) 2025 Mar 19;14(3)
Antioxidants (Basel, Switzerland) 2025 Mar 19;14(3)
Supplementing Freezing Medium with Crocin Exerts a Protective Effect on Bovine Spermatozoa Through the Modulation of a Heat Shock-Mediated Apoptotic Pathway.
Sapanidou V, Tsantarliotou MP, Feidantsis K, Tzekaki EE, Kourousekos G, Lavrentiadou SN
Molecules (Basel, Switzerland) 2025 Mar 16;30(6)
Molecules (Basel, Switzerland) 2025 Mar 16;30(6)
Activated NETosis of bone marrow neutrophils up-regulates macrophage osteoclastogenesis via cGAS-STING/AKT2 pathway to promote osteoporosis.
Guo Y, Zhou H, Wang Y, Gu Y
Experimental cell research 2025 Mar 15;446(2):114477
Experimental cell research 2025 Mar 15;446(2):114477
Integrative multi-omics reveals the mechanism of ulcerative colitis treated with Ma-Mu-Ran antidiarrheal capsules.
Huang H, Duan B, Huang Z, Wang S, Wen Y, Jiang Q, Chen P, Huang P, Liu J, Zheng S, Ye Y, Zhang D, Wang Q, Huang F, Li J, Han L
Rapid communications in mass spectrometry : RCM 2025 Mar 15;39(5):e9939
Rapid communications in mass spectrometry : RCM 2025 Mar 15;39(5):e9939
LXRα agonists ameliorates acute rejection after liver transplantation via ABCA1/MAPK and PI3K/AKT/mTOR signaling axis in macrophages.
Qin X, Hu D, Li Q, Zhang S, Qin Z, Wang L, Liao R, Wu Z, Liu Y
Molecular medicine (Cambridge, Mass.) 2025 Mar 14;31(1):99
Molecular medicine (Cambridge, Mass.) 2025 Mar 14;31(1):99
Integration of single-cell RNA sequencing and network pharmacology to elucidate the effect of Yantiao Formula on alleviating ALI by regulating the polarization of alveolar macrophages.
Liu D, Zhang Y, Bai B, Xiong X, Zhou Q, Shi R
Journal of ethnopharmacology 2025 Mar 13;343:119436
Journal of ethnopharmacology 2025 Mar 13;343:119436
Injectable hydrogels with ROS-triggered drug release enable the co-delivery of antibacterial agent and anti-inflammatory nanoparticle for periodontitis treatment.
Zhu Y, Xiu Z, Jiang X, Zhang H, Li X, Feng Y, Li B, Cai R, Li C, Tao G
Journal of nanobiotechnology 2025 Mar 12;23(1):205
Journal of nanobiotechnology 2025 Mar 12;23(1):205
Microneedles Loaded with Nitric-Oxide Driven Nanomotors Improve Force-Induced Efferocytosis Impairment and Sterile Inflammation by Revitalizing Macrophage Energy Metabolism.
Tan H, Wang S, He X, Yang G, Zhu Y, Yang S, Yan S, Gong C, Bai W, Hu Y, Song J, Zheng L
ACS nano 2025 Mar 11;19(9):9390-9411
ACS nano 2025 Mar 11;19(9):9390-9411
Orally-administrable supramolecular probiotic capsules enable cooperative colon-targeted inflammation inhibition for ameliorating ulcerative colitis.
Wang T, Chen J, Shu C, Shen X, Fu Y, Li M, Luo Z
Acta biomaterialia 2025 Mar 1;194:396-410
Acta biomaterialia 2025 Mar 1;194:396-410
GSK3β Substrate-competitive Inhibitors Regulate the gut Homeostasis and Barrier Function to Inhibit Neuroinflammation in Scopolamine-induced Alzheimer's Disease Model Mice.
Zhang L, Jiang Z, Hu S, Ni H, Zhao Y, Tan X, Lang Y, Na R, Li Y, Du Q, Li QX, Dong Y
Inflammation 2025 Jun;48(3):1438-1459
Inflammation 2025 Jun;48(3):1438-1459
L-arginine modified mesoporous bioactive glass with ROS scavenging and NO release for periodontitis treatment.
Yao H, Turali Emre ES, Fan Y, Wang J, Liu F, Wei J
Bioactive materials 2025 Jun;48:200-216
Bioactive materials 2025 Jun;48:200-216
Mesenchymal Stem Cells Attenuate Podocyte Injury in Diabetic Nephropathy Through the Promotion of Type 2 Macrophage Polarization.
Zhu X, Wang Y, Sun Z, Cheng W, Chen K, Gao X, Meng J, Li S, Zheng W, Wang Y, Yin X, Zhou X
Stem cells and development 2025 Jun;34(11-12):258-270
Stem cells and development 2025 Jun;34(11-12):258-270
Multifunctional injectable hydrogel incorporating EGCG-Cu complexes for synergistic antibacterial, immunomodulatory, and osteogenic therapy in periodontitis.
Hu Y, Xu W, Sun L, Ma X, Zhou P, Zhang C, Cai R, Wang X, Yang H, Tao G, Chen J, He Y
Materials today. Bio 2025 Jun;32:101907
Materials today. Bio 2025 Jun;32:101907
Curcumin-encapsulated exosomes in bisphosphonate-modified hydrogel microspheres promote bone repair through macrophage polarization and DNA damage mitigation.
Si Y, Dong S, Li M, Gu J, Luo M, Wang X, Wang Z, Li X, Zhang C
Materials today. Bio 2025 Jun;32:101874
Materials today. Bio 2025 Jun;32:101874
Enhanced inhibition of neuronal ferroptosis and regulation of microglial polarization with multifunctional traditional Chinese medicine active ingredients-based selenium nanoparticles for treating spinal cord injury.
Mai L, Liu J, Wu H, Wang H, Lin Z, Rao S, Sun W, Tan A, Lin Y, Chen B
Materials today. Bio 2025 Jun;32:101758
Materials today. Bio 2025 Jun;32:101758
Ultrasound-responsive taurine lipid nanoparticles attenuate oxidative stress and promote macrophage polarization for diabetic wound healing.
Luo Z, Zheng S, Hu Z, Li P, Zeng J, Lu Y, Ali M, Chen Z, Wang Q, Qi F
Free radical biology & medicine 2025 Jun;233:302-316
Free radical biology & medicine 2025 Jun;233:302-316
Liposome of Phlorizin promote the repair of carotid atherosclerosis in rats by regulating inflammation and the Nrf2 signaling pathway.
Wu X, Ding C, Liu X, Ding Q, Zhang S, Wang Y, Zhao T, Liu W
Biochimica et biophysica acta. Molecular and cell biology of lipids 2025 Jun;1870(5):159613
Biochimica et biophysica acta. Molecular and cell biology of lipids 2025 Jun;1870(5):159613
Scutellaria baicalensis Extracts Restrict Intestinal Epithelial Cell Ferroptosis by Regulating Lipid Peroxidation and GPX4/ACSL4 in Colitis.
Zhang J, Tan B, Wu H, Han T, Fang D, Cai H, Hu B, Kang A
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156708
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156708
Biochanin A mitigates colitis by inhibiting ferroptosis-mediated intestinal barrier dysfunction, oxidative stress, and inflammation via the JAK2/STAT3 signaling pathway.
Deng B, Wang K, He H, Xu M, Li J, He P, Liu Y, Ma J, Zhang J, Dong W
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156699
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156699
Abnormal iron metabolism in the zona incerta in Parkinson's disease mice.
Xiu M, Liu Y, Wang Z, Zhang J, Shi Y, Xie J, Shi L
Journal of neural transmission (Vienna, Austria : 1996) 2025 Jun;132(6):845-857
Journal of neural transmission (Vienna, Austria : 1996) 2025 Jun;132(6):845-857
Therapeutic Delivery of circDYM by Perillyl Alcohol Nanoemulsion Alleviates LPS-Induced Depressive-Like Behaviors.
Gao F, Zhang Z, Ju M, Bian L, Wang H, Zhao S, Cai N, Wang Y, Jia Y, Shen L, Zhang Y, Yao H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(21):e2414559
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(21):e2414559
Luteolin ameliorates kainic acid-induced seizure by modulating GADD45B and reducing oxidative stress in hippocampal neurons.
Luo C, Wang Z, Liao J, Fu C, Zhang F, Zhao J
Neuropeptides 2025 Jun;111:102524
Neuropeptides 2025 Jun;111:102524
Dehydrodiisoeugenol targets NOD2 exerting dual effects against colitis and colorectal cancer: a double-edged sword.
Yi F, Chen N, Zhao M, Gu Z, Yuan Y, Tang X, Liu F
Molecular medicine (Cambridge, Mass.) 2025 Jun 5;31(1):221
Molecular medicine (Cambridge, Mass.) 2025 Jun 5;31(1):221
IL-37 inhibited inflammation to improve gestational diabetes mellitus through the GSK3/NF-κB pathway.
Song M, Zhang G
Diabetology & metabolic syndrome 2025 Jun 5;17(1):193
Diabetology & metabolic syndrome 2025 Jun 5;17(1):193
Malvidin Alleviates Lipopolysaccharide-Induced Acute Lung Injury by Modulating JAK2/STAT3 Signaling to Inhibit Macrophage M1 Polarization and Oxidative Stress.
Mao X, Liu X, Wei C, Tang H, Yin F, Zhang Z, Yu K, Liu H, Wang C, Le A
Journal of agricultural and food chemistry 2025 Jun 4;73(22):13488-13501
Journal of agricultural and food chemistry 2025 Jun 4;73(22):13488-13501
Cerium-Organic Framework and Resveratrol Composite Hydrogel Scaffold with Dual Antioxidant Activity for Enhanced Bone Regeneration.
Lu Y, Zhang L, Yang B, Hu H, Sun H, Guo D
ACS applied materials & interfaces 2025 Jun 4;17(22):31828-31842
ACS applied materials & interfaces 2025 Jun 4;17(22):31828-31842
Pretreatment with Citrus reticulata 'Chachi' Polysaccharide Alleviates Alcohol-Induced Gastric Ulcer by Inhibiting NLRP3/ASC/Caspase-1 and Nrf2/HO-1 Signaling Pathways.
Liang H, Liang Y, Wu L, Lin L, Yao Y, Deng J, Xu J, Li H, Gao F, Xing W, Yu M, Jia X, Wei M, Li C, Zheng G
Nutrients 2025 Jun 20;17(13)
Nutrients 2025 Jun 20;17(13)
Xanthoxylin Regulating the Inflammatory Microenvironment After Spinal Cord Injury Through Inhibition of the NF-κB Signaling Pathway.
Fan Z, Ye L, Wang S, Zhu Z, Wu C, Wu C, Kong L, Ning R
Neuromolecular medicine 2025 Jun 19;27(1):47
Neuromolecular medicine 2025 Jun 19;27(1):47
A Slow Hydrogen Sulfide Donor GYY-4137 Partially Improves Vascular Function in Spontaneously Hypertensive Rats Fed a High-Fat Diet.
Aydemir BG, Berenyiova A, Cebova M, Henderson JD, Barta A, Cacanyiova S
Pathophysiology : the official journal of the International Society for Pathophysiology 2025 Jun 18;32(2)
Pathophysiology : the official journal of the International Society for Pathophysiology 2025 Jun 18;32(2)
Novel insights into beta cell ER stress CHOP and its role in HFpEF development.
Srinivas B, Fortuno P, Peng H, Xu J, Suhail H, Sabbah HN, Rhaleb NE, Matrougui K
Cardiovascular diabetology 2025 Jun 13;24(1):250
Cardiovascular diabetology 2025 Jun 13;24(1):250
Celastrol improves endothelial function in diet-induced obesity mice via attenuating endoplasmic reticulum stress through the activation of AMPK pathway.
Yu C, Lin W, Yang J, Jiang Q, Liu W, Liu H, Lin Y, Wang L, Chen L, Huang Y, Chen L
Molecular medicine (Cambridge, Mass.) 2025 Jun 11;31(1):233
Molecular medicine (Cambridge, Mass.) 2025 Jun 11;31(1):233
A Dual-Factor Scaffold for Spinal Cord Injury Repair Targeting Inflammation and Ferroptosis.
Zou X, Zhu Y, Shu H, Su X, Xiong J, Ye W, Tang P, Wang H, Gao Y, Song T, Zou Z, Cai W
ACS applied materials & interfaces 2025 Jun 11;17(23):33540-33554
ACS applied materials & interfaces 2025 Jun 11;17(23):33540-33554
Platelet Membrane-Coated Drug-Loaded Nanoparticles for Dual-Modal Imaging and Photodynamic Therapy in Triple-Negative Breast Cancer.
Ma K, Yang M, Pan Y, Bao Y, Bao Y, Mai X
ACS applied materials & interfaces 2025 Jun 11;17(23):33513-33527
ACS applied materials & interfaces 2025 Jun 11;17(23):33513-33527
Oxidized fucoidan-based nanocomposite hydrogel for cryptotanshinone delivery and prevention of postoperative abdominal adhesions.
Zhang T, Shi X, Huang Y, Gong Y, He Y, Xiao D, Wang S, Zhao C
Journal of controlled release : official journal of the Controlled Release Society 2025 Jun 10;382:113733
Journal of controlled release : official journal of the Controlled Release Society 2025 Jun 10;382:113733
Fate reversal: Exosome-driven macrophage rejuvenation and bacterial-responsive drug release for infection immunotherapy in diabetes.
Zou J, Cui W, Deng N, Li C, Yang W, Ye X, Yao F, Zhang T, Xiao J, Ma C, Wu L, Dong D, Chen J, Guo C, Liu A, Wu H
Journal of controlled release : official journal of the Controlled Release Society 2025 Jun 10;382:113730
Journal of controlled release : official journal of the Controlled Release Society 2025 Jun 10;382:113730
Secretome enriched with small extracellular vesicles derived from human gingiva-derived mesenchymal stem cells enhances rat tongue muscle regeneration.
Zhang Q, He P, Shi S, Xu Q, Granquist EJ, Winkelstein BA, Shanti RM, Le AD
Journal of nanobiotechnology 2025 Jun 10;23(1):434
Journal of nanobiotechnology 2025 Jun 10;23(1):434
Tinosinenside A inhibits neuroinflammation and protects HT22 cells by suppressing the TLR4/NF-κB/NLRP3 signaling pathway in BV2 cells.
Xie Y, Qin Y, Wang J, Xu Z, Chen L, Kuang Y, Yang R, Huang L
Naunyn-Schmiedeberg's archives of pharmacology 2025 Jul;398(7):8947-8962
Naunyn-Schmiedeberg's archives of pharmacology 2025 Jul;398(7):8947-8962
Quercetin protects against neuronal toxicity by activating the PI3K/Akt/GSK-3β pathway in vivo models of MPTP-induced Parkinson's disease.
Li Y, Man M, Tian Y, Zhao G, Liu F, Zhao J, Huang S, Xue J, Chang W
Inflammopharmacology 2025 Jul;33(7):4063-4076
Inflammopharmacology 2025 Jul;33(7):4063-4076
Methacrylated sericin/methacrylated hyaluronic acid composite microneedles with exosomes for diabetic wound healing.
Xu X, Shen Y, Wu J, Hong F, Xia H, Chen X, Lin G, Liu L, Xu RA
International journal of biological macromolecules 2025 Jul;318(Pt 1):144957
International journal of biological macromolecules 2025 Jul;318(Pt 1):144957
Bacillus paralicheniformis-mediated gut microbiota promotes M2 macrophage polarization by inhibiting P38 MAPK signaling to alleviate necrotizing enterocolitis and apoptosis in mice.
Yang S, Pan H, Wang T, Zhou X, Fan L, Xiao H, Zhou Z, Xiao Y, Shi D
Microbiological research 2025 Jul;296:128136
Microbiological research 2025 Jul;296:128136
Liyan Kaiyin Formula relieves reflux pharyngitis by regulating M1 macrophage polarization via the NF-κB/NLRP3 pathway.
Wang L, Chen X, Xu T, Fei Y, Yang Q, An J, Li Z, Wu K
Immunobiology 2025 Jul;230(4):153095
Immunobiology 2025 Jul;230(4):153095
Optimally Aligned Nerve Scaffolds with Sustained Astaxanthin Release Improve the Inflammatory Microenvironment through Mitophagy Activation.
Jin X, Liu S, Fang J, Chen F, Xu B, Nan L, Zhao S, Wu Z, Guan Z, Tao K, Liu J
Small (Weinheim an der Bergstrasse, Germany) 2025 Jul;21(26):e2502939
Small (Weinheim an der Bergstrasse, Germany) 2025 Jul;21(26):e2502939
p16INK4a downregulation alleviates temporomandibular joint osteoarthritis combined with type 2 diabetes by driving M2 polarization.
Cai J, Zhang L, Du Q, Wang M, Ma X, Chen Y, Wang Y, Yuan H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2025 Jul;188:118172
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2025 Jul;188:118172
β-Glucuronidase-Expressing Lactobacillus reuteri Triggers Irinotecan Enterotoxicity Through Depleting the Regenerative Epithelial Stem/Progenitor Pool.
Yue B, Gao R, Zhao L, Liu D, Lv C, Wang Z, Ai F, Zhang B, Yu Z, Geng X, Wang H, Wang K, Chen K, Liu C, Wang Z, Dou W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jul;12(26):e2411052
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jul;12(26):e2411052
Evidence for imbalanced polarization of caruncle macrophages in retained placenta of dairy cows.
Zhang H, Li M, Zhao B, Chang R, Wang J, Yang Y, Huang Q, Aernouts B, Jiang Q, Loor JJ, Xu C
Journal of dairy science 2025 Jul;108(7):7437-7451
Journal of dairy science 2025 Jul;108(7):7437-7451
Adipose Mesenchymal Stem Cells Derived Exosomes Ameliorates KOA Cartilage Damage and Inflammation by Activation of PINK1-Mediated Mitochondrial Autophagy.
Kang J, Jie L, Fu H, Zhang L, Lu G, Yu L, Tian D, Liao T, Yin S, Xin R, Wang P
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jul 31;39(14):e70811
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jul 31;39(14):e70811
miR-708-5p Attenuates Osteoarthritis Progression via Multi-Target Modulation of the NOX4/NF-κB Axis and Cartilage Homeostasis.
Huang SH, Liu ZM, Chen SJ, Tu PY, Tien YC, Lu CC, Wang CC, Chen LM, Shen PC
Cartilage 2025 Jul 30;:19476035251361679
Cartilage 2025 Jul 30;:19476035251361679
Salvianolic Acid B Attenuates Liver Fibrosis via Suppression of Glycolysis-Dependent m1 Macrophage Polarization.
Song H, Li ZW, Xu W, Tan Y, Kuang M, Pei G, Wang ZQ
Current issues in molecular biology 2025 Jul 29;47(8)
Current issues in molecular biology 2025 Jul 29;47(8)
A cell-free SHED lysate-hydrogel system for oral ulcer healing with anti-inflammatory and pro-angiogenic effects.
Dong N, Zhang C, Zhang Q, Bao S, Hu Y, Xu H, Dai P, Li C, Li S, Wu P, Xu J, Cai X, Wang Z, Luo L
Journal of nanobiotechnology 2025 Jul 28;23(1):547
Journal of nanobiotechnology 2025 Jul 28;23(1):547
Deficiency of inducible nitric oxide synthase (iNOS) enhances MC903-induced atopic dermatitis-like inflammation in mice.
Luo J, Li C, Zhu Y, Guo R, Huang J, Yu H, Sun M, Zhu Q, Guo Q, Li Y, Guo P, Su L, Hu L
Biochemical and biophysical research communications 2025 Jul 22;771:152028
Biochemical and biophysical research communications 2025 Jul 22;771:152028
Activation of Hippocampal ACE2 Prevents the Dysbiosis-induced Depression-like Behavior in Mice by Enhanced Neurogenesis and Neuroprotection via Mas Receptor.
Takahashi K, Nakagawasai O, Kurokawa K, Miyagawa K, Mochida-Saito A, Takeda H, Tsuji M
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2025 Jul 18;20(1):71
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2025 Jul 18;20(1):71
Urine-derived stem cells from patients alleviate lupus nephritis via regulating macrophage polarization in a CXCL14-dependent manner.
Xia Y, Zhang Y, Ji J, Feng G, Chen T, Li H, Zhou F, Bao Y, Zeng X, Gu Z
Life sciences 2025 Jul 1;372:123623
Life sciences 2025 Jul 1;372:123623
A Zinc-Citrate Metal-Organic Framework-Based Adaptable Hydrogen Sulfide Delivery System for Regulating Neuroregeneration Microenvironment in Spinal Cord Injury.
Yao Y, Dong X, Pang Z, Shao J, He Z, Liu K, Hou P, Hu F, Liu W, Huo Y, Wang H, Dai H, Zhang X
ACS nano 2025 Jul 1;19(25):22798-22819
ACS nano 2025 Jul 1;19(25):22798-22819
RNA-seq shows Angiopoietin-like 4 promotes hepatocellular carcinoma progression by inducing M2 polarization of tumor-associated macrophages.
Cui G, Liu W, Sun X, Bai Y, Ding M, Zhao N, Guo J, Qu D, Wang S, Qin L, Yang Y
International journal of biological macromolecules 2025 Jan;287:138523
International journal of biological macromolecules 2025 Jan;287:138523
Immunomodulatory and osteogenic effects of chitosan-based injectable hydrogel with geniposide-loaded mesoporous bioactive glass.
Deng Y, Yao H, Zhao J, Wei J
International journal of biological macromolecules 2025 Jan;284(Pt 2):138050
International journal of biological macromolecules 2025 Jan;284(Pt 2):138050
ROS Responsive Cerium Oxide Biomimetic Nanoparticles Alleviates Calcium Oxalate Crystals Induced Kidney Injury via Suppressing Oxidative Stress and M1 Macrophage Polarization.
He Y, Peng E, Ba X, Wu J, Deng W, Huang Q, Tong Y, Shang H, Zhong Z, Liu X, Zhang Y, Ye T, Yang X, Wang K, Xie Y, Jiang K, Xia D, Chen Z, Tang K
Small (Weinheim an der Bergstrasse, Germany) 2025 Jan;21(3):e2405417
Small (Weinheim an der Bergstrasse, Germany) 2025 Jan;21(3):e2405417
Pimpinellin mitigates DSS-induced ulcerative colitis in mice by reducing inflammation and regulating gut microbiota.
Lv B, Hou L, Zhang H, Hao C, Song Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156308
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156308
Xibining inhibition of the PI3K-AKT pathway reduces M1 macrophage polarization to ameliorate KOA synovial inflammation and nociceptive sensitization.
Jie L, Zhang L, Fu H, Kang J, Huang Z, Zhu Z, Yin S, Wu P, Wang P, Mei W, Li X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156281
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156281
Cannabidiol regulates L-carnitine and butyric acid metabolism by modulating the gut microbiota to ameliorate collagen-induced arthritis.
Geng Q, Wang Z, Shi T, Wen C, Xu J, Jiao Y, Diao W, Gu J, Wang Z, Zhao L, Deng T, Xiao C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156270
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156270
Hyperlipidemia exacerbates acute pancreatitis via interactions between P38MAPK and oxidative stress.
Qiu M, Huang Y, Zhou X, Yu J, Li J, Wang W, Zippi M, Fiorino S, Hong W
Cellular signalling 2025 Jan;125:111504
Cellular signalling 2025 Jan;125:111504
DLK1 regulates periodontal inflammation by inhibiting NF-κB p65 and JNK signaling pathways.
Hong Y, Xu L, Yu X, He Y, Du Y
Odontology 2025 Jan;113(1):349-357
Odontology 2025 Jan;113(1):349-357
Administration of 2-deoxy-D-glucose alleviates cancer-induced bone pain by suppressing microglial polarization to the M1 phenotype and neuroinflammation.
Liu L, Li DY, Zhang LQ, Gao SJ, Song FH, Wu JY, Zhou YQ, Liu DQ, Mei W
Molecular pain 2025 Jan-Dec;21:17448069251348778
Molecular pain 2025 Jan-Dec;21:17448069251348778
Inhibition of macrophage polarization and pyroptosis in collagen-induced arthritis through MSC-exo and ginsenoside Rh2.
Zhou Z, Wu S, Li Y, Shao P, Jiang J
Arthritis research & therapy 2025 Jan 9;27(1):6
Arthritis research & therapy 2025 Jan 9;27(1):6
Pterostilbene protects against lipopolysaccharide-induced inflammation and blood-brain barrier disruption in immortalized brain endothelial cell lines in vitro.
Zhou Y, Yang Y, Tian R, Cheang WS
Scientific reports 2025 Jan 9;15(1):1542
Scientific reports 2025 Jan 9;15(1):1542
A Disintegrin and Metalloproteinase 17 Disrupts Bovine Macrophage MER Proto-Oncogene Tyrosine Kinase Integrity to Impede Apoptotic Cell Clearance and Promote Inflammation in Clinical Mastitis.
Wang J, Li M, Zhao B, Chang R, Wu W, Zhang H, Usman M, Loor JJ, Xu C
Journal of agricultural and food chemistry 2025 Jan 8;73(1):549-561
Journal of agricultural and food chemistry 2025 Jan 8;73(1):549-561
Ultrasound-Triggered Nanogel Boosts Chemotherapy and Immunomodulation in Colorectal Cancer.
Cui R, Zhou J, Yang W, Chen Y, Chen L, Tan L, Zhang F, Liu G, Yu J
ACS applied materials & interfaces 2025 Jan 8;17(1):211-221
ACS applied materials & interfaces 2025 Jan 8;17(1):211-221
SIX1 aggravates the progression of spinal cord injury in mice by promoting M1 polarization of microglia.
Xu Z, Zhu M, Xie H, Zhu J, Zheng H, Liu X, Zhang Y, Liu J
Scientific reports 2025 Jan 8;15(1):1283
Scientific reports 2025 Jan 8;15(1):1283
Natural phenol carbamates: Selective BuChE/FAAH dual inhibitors show neuroprotection in an Alzheimer's disease mouse model.
Rong K, Li Z, Wu X, Gao S, Zhao J, Yang J, Jiang X, Zhang J, Tang W
European journal of medicinal chemistry 2025 Jan 5;281:117003
European journal of medicinal chemistry 2025 Jan 5;281:117003
The structural features and anti-inflammatory properties of a glucogalactan from Holotrichia diomphalia Bates (Qi Cao).
Liu WJ, Xu DQ, Cui DX, Fu RJ, Jing H, Li XQ, Cao W, Tang YP
Journal of ethnopharmacology 2025 Jan 30;337(Pt 3):118948
Journal of ethnopharmacology 2025 Jan 30;337(Pt 3):118948
ROS-regulated SUR1-TRPM4 drives persistent activation of NLRP3 inflammasome in microglia after whole-brain radiation.
Chang Y, He Y, Wang D, Zhang K, Zhang Y, Li Z, Zeng S, Xiao S, Pan S, Huang K
Acta neuropathologica communications 2025 Jan 27;13(1):16
Acta neuropathologica communications 2025 Jan 27;13(1):16
Positive feedback loop involving AMPK and CLYBL acetylation links metabolic rewiring and inflammatory responses.
Wang W, Wu B, Hao M, Chen S, Cong R, Wu W, Wang P, Zhang Q, Jia P, Song Y, Liu B, Qu S, Pei JF, Li D, Zhang N
Cell death & disease 2025 Jan 25;16(1):41
Cell death & disease 2025 Jan 25;16(1):41
Zinc-induced photocrosslinked konjac glucomannan/glycyrrhizic acid hydrogel promotes skin wound healing in diabetic mice through immune regulation.
Li J, Wu D, Su Z, Guo J, Cui L, Su H, Chen Y, Yu B
Carbohydrate polymers 2025 Jan 15;348(Pt A):122780
Carbohydrate polymers 2025 Jan 15;348(Pt A):122780
iNOS-Produced Nitric Oxide from Cancer Cells as an Intermediate of Stemness Regulation by PARP-1 in Colorectal Cancer.
Del Moral-Martinez M, Sánchez-Uceta P, Clemente-Gonzalez R, Moreno-SanJuan S, Puentes-Pardo JD, Khaldy H, Lopez-Perez D, Arnedo J, Casado J, Martínez-Heredia L, Carazo A, León J
Biomolecules 2025 Jan 14;15(1)
Biomolecules 2025 Jan 14;15(1)
Luteolin modulates macrophage phenotypic switching via the AMPK-PPARγ pathway to alleviate ulcerative colitis in mice.
Yang S, Duan H, Zeng J, Yan Z, Niu T, Ma X, Zhang Y, Hu J, Zhang L, Zhao X
Journal of ethnopharmacology 2025 Jan 13;339:119157
Journal of ethnopharmacology 2025 Jan 13;339:119157
Dentin tubules as a long-term sustained release carrier to accelerate bone repair by loading FTY720.
Xie J, Huang H, Xu S, Zhou K, Chen X, Fang J, Zhao F
Journal of controlled release : official journal of the Controlled Release Society 2025 Jan 10;377:446-457
Journal of controlled release : official journal of the Controlled Release Society 2025 Jan 10;377:446-457
Gut commensal bacteria Parabacteroides goldsteinii-derived outer membrane vesicles suppress skin inflammation in psoriasis.
Su D, Li M, Xie Y, Xu Z, Lv G, Jiu Y, Lin J, Chang CJ, Chen H, Cheng F
Journal of controlled release : official journal of the Controlled Release Society 2025 Jan 10;377:127-145
Journal of controlled release : official journal of the Controlled Release Society 2025 Jan 10;377:127-145
Silk-engineered bioactive nanoparticles for targeted alleviation of acute inflammatory disease via macrophage reprogramming.
Liu R, Zhao E, Wang Y, Zuo H, Li L, Xia Q, He H
Journal of nanobiotechnology 2025 Jan 10;23(1):11
Journal of nanobiotechnology 2025 Jan 10;23(1):11
Hyperactivity of the IL-33-ILC2s-IL-13-M-MDSCs axis promotes cervical cancer progression.
Wang B, Zhu Y, Zhang Y, Ru Z, Chen L, Zhang M, Wu Y, Ding J, Chen Z
International immunopharmacology 2025 Jan 10;144:113693
International immunopharmacology 2025 Jan 10;144:113693
N 6-Methyladenosine Demethylase FTO Controls Macrophage Homeostasis in Diabetic Vasculopathy.
Feng S, Zhang Q, Liu Q, Huang C, Zhang H, Wang F, Zhu Y, Jian Q, Chen X, Jiang Q, Yan B
Diabetes 2025 Jan 1;74(1):82-95
Diabetes 2025 Jan 1;74(1):82-95
Using chondroitin sulfate lithium hydrogel for diabetic bone regeneration via regulation of macrophage polarization.
Xu C, Li W, Mao J, Liu Z, Lao A, Mao L, Gu A, Wu J, Shen A, Lin K, Liu J
Carbohydrate polymers 2025 Jan 1;347:122787
Carbohydrate polymers 2025 Jan 1;347:122787
Macrophage metabolic reprogramming ameliorates diabetes-induced microvascular dysfunction.
Zhang QY, Zhang HY, Feng SG, Yao MD, Ding JJ, Li XM, Ye R, Liu Q, Yao J, Yan B
Redox biology 2025 Feb;79:103449
Redox biology 2025 Feb;79:103449
Network pharmacology and animal experiments revealed the protective effects of Guilong prescription on chronic prostatitis and its possible mechanisms.
Peixuan Z, Zeqi SU, Qiongyin F, Cai Z, Ting W
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2025 Feb;45(1):89-99
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2025 Feb;45(1):89-99
Suramin enhances proliferation, migration, and tendon gene expression of human supraspinatus tenocytes.
Huang SH, Wang CC, Shen PC, Liu ZM, Chen SJ, Tien YC, Lu CC
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2025 Feb;43(2):252-263
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2025 Feb;43(2):252-263
Long-term treatment with the streptococcal exotoxin streptolysin O inhibits vascular smooth muscle contraction by inducing iNOS expression in endothelial cells.
Seki M, Mukohda M, Tajima H, Morikita N, Imai R, Itaya K, Mizuno R, Ozaki H
The Journal of pharmacology and experimental therapeutics 2025 Feb;392(2):100011
The Journal of pharmacology and experimental therapeutics 2025 Feb;392(2):100011
Functionalized Nanozyme Microcapsules Targeting Deafness Prevention via Mitochondrial Homeostasis Remodeling.
Ge S, Sun A, Zhou X, Niu P, Chen Y, Bao X, Yu M, Zhong Z, Sun J, Li G
Advanced materials (Deerfield Beach, Fla.) 2025 Feb;37(5):e2413371
Advanced materials (Deerfield Beach, Fla.) 2025 Feb;37(5):e2413371
Programmed surface platform orchestrates anti-bacterial ability and time-sequential bone healing for implant-associated infection.
Yu Z, Wang Z, Chen Y, Wang Y, Tang L, Xi Y, Lai K, Zhang Q, Li S, Xu D, Tian A, Wu M, Wang Y, Yang G, Gao C, Huang T
Biomaterials 2025 Feb;313:122772
Biomaterials 2025 Feb;313:122772
ZIP8 Regulates Inflammation and Macrophage Polarisation in Intervertebral Disc Degeneration via the Wnt/β-Catenin Pathway.
Xu J, Gu H, Zhou K, Wu L, Zhang Y, Bian C, Huang Z, Chen G, Cheng X, Yin X
Journal of cellular and molecular medicine 2025 Feb;29(4):e70431
Journal of cellular and molecular medicine 2025 Feb;29(4):e70431
Stigmasterol from Prunella vulgaris L. Alleviates LPS-induced mammary gland injury by inhibiting inflammation and ferroptosis.
Sun M, Xu D, Liu D, Ran X, Li F, Wang J, Ge Y, Liu Y, Guo W, Liu J, Cao Y, Fu S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Feb;137:156362
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Feb;137:156362
Demyelination of the amygdala mediates psychological stress-induced emotional disorders partially contributed by activation of P2X7R/NLRP3 cascade.
Li Y, Zhang Y, Lin D, Fu X, Jing C
Brain, behavior, and immunity 2025 Feb;124:365-375
Brain, behavior, and immunity 2025 Feb;124:365-375
Phillyrin ameliorates DSS-induced colitis in mice via modulating the gut microbiota and inhibiting the NF-κB/MLCK pathway.
Li T, Hu G, Fu S, Qin D, Song Z
Microbiology spectrum 2025 Feb 4;13(2):e0200624
Microbiology spectrum 2025 Feb 4;13(2):e0200624
Bioactive Decellularized Extracellular Matrix Platform Integrating Multifunctional Nanozymes and Cell-Laden Microgels for Acute Liver Failure Treatment.
Chen X, Zhang J, Lin T, Zhou F, Li F, Xue T, Zhong Q, Lee W, Chen G, Wang H, Ju E, Li M, Tao Y
ACS nano 2025 Feb 25;19(7):6890-6910
ACS nano 2025 Feb 25;19(7):6890-6910
ITIH5-mediated fibroblast/macrophage crosstalk exacerbates cardiac remodelling after myocardial infarction.
Wu Y, Meng L, Zhan S, Li M, Huang J, Chen X, Chen L, Gao X, Chen H, Chen H, Zhong Y, Xu L, Xu Y
Journal of translational medicine 2025 Feb 24;23(1):224
Journal of translational medicine 2025 Feb 24;23(1):224
Dapagliflozin alleviated seizures and cognition impairment in pilocarpine induced status epilepticus via suppressing microglia-mediated neuroinflammation and oxidative stress.
Liu Y, Yu Y, Chen C, Wu X, Zheng Q, Zhang X, Ye L, Zhang C, Feng Z
International immunopharmacology 2025 Feb 20;148:114117
International immunopharmacology 2025 Feb 20;148:114117
MiR-186-5p carried by M2 macrophage-derived exosomes downregulates TRPP2 expression in airway smooth muscle to alleviate asthma progression.
Wang Z, Ren Y, Li Y, Zhang Y, Bai S, Hou W, Zhang W, Yao Y, Zhao H, Wang M, Luo Y, Pang G, Du J
International immunopharmacology 2025 Feb 20;148:114107
International immunopharmacology 2025 Feb 20;148:114107
TREM2 Alleviates Neuroinflammation by Maintaining Cellular Metabolic Homeostasis and Mitophagy Activity During Early Inflammation.
Hu L, Liu J, Peng J, Li X, Huang Z, Zhang C, Fan S
Diseases (Basel, Switzerland) 2025 Feb 16;13(2)
Diseases (Basel, Switzerland) 2025 Feb 16;13(2)
Micheliolide attenuates sepsis-induced acute lung injury by suppressing mitochondrial oxidative stress and PFKFB3-driven glycolysis.
Li W, Li Y, Xiao L, Xie Z, Peng J, Huang W, Li X, Meng Y
Journal of translational medicine 2025 Feb 14;23(1):181
Journal of translational medicine 2025 Feb 14;23(1):181
Intelligent sequential degradation hydrogels by releasing bimetal-phenolic for enhanced diabetic wound healing.
Zhang Y, Tang Z, Chen L, Yang M, Zeng Y, Bai X, Zhang B, Zhou J, Zhang W, Tang S
Journal of controlled release : official journal of the Controlled Release Society 2025 Feb 10;378:961-981
Journal of controlled release : official journal of the Controlled Release Society 2025 Feb 10;378:961-981
Reactive Oxygen Species-Responsive Gel-Based Microneedle Patches with Antimicrobial and Immunomodulating Properties for Oral Mucosa Disease Treatment.
Zhang X, Zhong G, Peng S, Zhang C, Li B, Xia Z, Zhu Y, Tao G, Cai R, Xu X
ACS biomaterials science & engineering 2025 Feb 10;11(2):1106-1122
ACS biomaterials science & engineering 2025 Feb 10;11(2):1106-1122
Carboxymethyl chitosan and sodium alginate oxide pH-sensitive dual-release hydrogel for diabetes wound healing: The combination of astilbin liposomes and diclofenac sodium.
Wu X, Wang Y, Liu X, Ding Q, Zhang S, Wang Y, Chai G, Tang Y, Yang J, Yu T, Liu W, Ding C
Carbohydrate polymers 2025 Feb 1;349(Pt B):122960
Carbohydrate polymers 2025 Feb 1;349(Pt B):122960
AEBP1 targets DDR2 to induce ferroptosis and microglial activation through the STAT3/P53 signaling pathway, exacerbating depression risk.
Zou Q, Zeng Z, Wan Y, Deng Y, Sun W
Archives of biochemistry and biophysics 2025 Dec;774:110632
Archives of biochemistry and biophysics 2025 Dec;774:110632
WWP2 Overexpression Represses NLRP3 Inflammasome Activation in Cerebral Ischemia/Reperfusion Injury Through the Degradation of MAVS.
Yu H, Li J, Lu T, Dai M, Wan X
Glia 2025 Dec;73(12):2445-2463
Glia 2025 Dec;73(12):2445-2463
Uncovering the mechanistic basis of Rheum palmatum L. (rhubarb) in the treatment of chronic kidney disease: an integrative approach using network pharmacology, molecular docking, and experimental validation.
He W, Wei Z, Li S, Han S, Ma J, Wu L, Lu D, Ta G
Pharmaceutical biology 2025 Dec;63(1):582-606
Pharmaceutical biology 2025 Dec;63(1):582-606
PINK1 overexpression suppresses p38 MAPK/NF‑κB signaling to attenuate chondrocyte senescence in osteoarthritis.
Jie L, Zhang Y, Liu J, Fu H, Zhu Z, Huang Z, Shi X, Wang P, Yin S
International journal of molecular medicine 2025 Dec;56(6)
International journal of molecular medicine 2025 Dec;56(6)
Self-assembled hybrid hydrogel microspheres create a bone marrow-mimicking niche for bone regeneration.
He Z, Hu P, Li Z, Mao K, Zheng J, Yang CY, Luo Y, Yang J, Cao Z, Lu J, Luo X, Tong S, He Z, Kim K, Liu Y, Sun X, Zhao L, Pan Y, Cao Y, Wang Y, Wang X
Bioactive materials 2025 Dec;54:179-200
Bioactive materials 2025 Dec;54:179-200
Baicalein alleviates long-term cognitive impairments induced by repeated neonatal sevoflurane exposure via inhibition of cortical microglial TLR4/NF-kB signaling.
Niu Y, Zeng Q, Yang Y, Liu W, Zhang H, Chen S, Li X
Brain, behavior, & immunity - health 2025 Dec;50:101126
Brain, behavior, & immunity - health 2025 Dec;50:101126
Activating Ferroptosis of M1 Macrophages: A Novel Mechanism of Asiaticoside Encapsuled in GelMA for Anti-Inflammation in Diabetic Wounds.
Cui S, Meng S, Liu Y, Chen S, Hu W, Huang Q, Chu Z, Zhong W, Ma L, Li Z, Jiang Y, Liu X, Fu X, Zhang C
Exploration (Beijing, China) 2025 Dec;5(6):20240062
Exploration (Beijing, China) 2025 Dec;5(6):20240062
AR Deficiency Protects Against Sepsis-Induced Acute Lung Injury by Inhibiting Macrophage M1 Polarization and Inflammatory Cytokine Secretion.
Wang X, Yin D, Sun J, Zhang L, Ye Y, Guo Q
Inflammation 2025 Dec;48(6):4203-4224
Inflammation 2025 Dec;48(6):4203-4224
Inhibition of Macrophage Activation by Minocycline Attenuates CCI-Induced Neuropathic Pain.
Ji YZ, Lin ZH, Liao CX, Wang Q, Chen FY, Su WF, Zhao YY, Chen G, Wei ZY
Inflammation 2025 Dec;48(6):3912-3926
Inflammation 2025 Dec;48(6):3912-3926
Genetic Ablation of miR-146a Induces Abdominal Aortic Aneurysm Formation by Intensifying Inflammatory M1-Like Macrophages Polarization and Vascular Smooth Muscle Cell Phenotypic Switching.
Zhong L, Sun Y, Chen G, Wang J, Yang Z, Lu W, Xiao X, Song H, Xiong J, Lin B, Wang K, Yang S, Bin J, Jiang X
Arteriosclerosis, thrombosis, and vascular biology 2025 Dec;45(12):2210-2225
Arteriosclerosis, thrombosis, and vascular biology 2025 Dec;45(12):2210-2225
Intelligent responsive PVA hydrogel loaded with composite MXene nanozyme enables efficient myocardial infarction repair by disrupting the oxidative stress-inflammation cascade.
Tong J, Sun D, Sun J, Zhang J, Chen M, Liu X, Zhang R, Zhang F, Zheng C, Wei Y, Guo X
Materials today. Bio 2025 Dec;35:102556
Materials today. Bio 2025 Dec;35:102556
Succinate Promotes M1 Polarization of Intestinal Macrophages in Mice With Necrotizing Enterocolitis Through the PI3K/AKT Pathway.
Liu S, Tang FL, Yan XL, Liu XC, Ai Q, Li LQ, Bao L
Pediatric discovery 2025 Dec;3(4):e70026
Pediatric discovery 2025 Dec;3(4):e70026
Dauricine Inhibits Macrophages M2 Polarization and Regulates the Progression and Ferroptosis via HCK/IDO1 in Urinary Bladder Cancer.
Gong J, Sun D, Zheng Y, Mao C, Yu B, Li X, Xuan Y
Food science & nutrition 2025 Dec;13(12):e71341
Food science & nutrition 2025 Dec;13(12):e71341
Size Effect of Mesoporous Bioactive Glass on Macrophage Polarization.
Luo J, Yao H, Zhang Y, Li Z, Wei J
ACS omega 2025 Dec 9;10(48):59159-59168
ACS omega 2025 Dec 9;10(48):59159-59168
Vasoactive Effects of Chronic Treatment with ACE Inhibitor Zofenopril in Zucker Obese Diabetic Rats: The Role of Nitroso and Sul?de Signalization.
Saman E, Cebova M, Majzunova M, Berenyiova A, Garaiova V, Cacanyiova S
Physiological research 2025 Dec 31;74(Suppl 2):S231-S244
Physiological research 2025 Dec 31;74(Suppl 2):S231-S244
N-acetylcysteine Restores Impaired Dentate Gyrus Neurogenesis in a Neonatal Maternal Separation Rat Model.
Kim HB, Kim YJ, Lim HM, Suh SW, Lee JH, Lee CJ, Woo RS
Experimental neurobiology 2025 Dec 31;34(6):277-288
Experimental neurobiology 2025 Dec 31;34(6):277-288
Comparative evaluation of the therapeutic efficacy between human amniotic epithelial cells and human umbilical cord mesenchymal stem cells in premature ovarian insufficiency.
Zhang Q, Wang J, Cheng Z, Cao W, Zhang Q, Lai D
Stem cell research & therapy 2025 Dec 31;17(1):65
Stem cell research & therapy 2025 Dec 31;17(1):65
Sirtuin 3 promotes osteogenic differentiation of bone marrow mesenchymal stem cells by regulating macrophage polarization under high glucose.
Lin L, Ren Y, Wang X, Liang H, Yao Q
Scientific reports 2025 Dec 25;16(1):3515
Scientific reports 2025 Dec 25;16(1):3515
Enhanced therapeutic efficacy of repeated bone marrow-derived MSC administration in a murine model of pulmonary fibrosis.
Zhou Z, Ding J, Han S, Duan Y, Chao J, Huang J
Stem cell research & therapy 2025 Dec 23;17(1):48
Stem cell research & therapy 2025 Dec 23;17(1):48
Exosome-mediated modulation of macrophage polarization and inflammation in early Klebsiella pneumoniae lung infections.
Liu Z, Ren P, Xue Y, Liu S, Li S, Li Y, Zhang Y
Clinical science (London, England : 1979) 2025 Dec 23;139(24):1691-1707
Clinical science (London, England : 1979) 2025 Dec 23;139(24):1691-1707
Decoding SDCBP's role in tumor progression and immune cells infiltration: from databases to macrophage validation.
Zhao C, Zhang C, Zhang X, Du C, Liu W, Zhou Q, Dong J, Yang F, Dang Y, Yang A, Wang M, Wang C, Li M
Discover oncology 2025 Dec 21;17(1):146
Discover oncology 2025 Dec 21;17(1):146
Human OCEL1 senses bacterial infection to unlock inflammatory responses.
Li Z, Wang J, Du J, Li J, Song Y, Zhu J, Li Z, Zhou W, Chen S, Yang L, Feng M, Cai X, Stacey KJ, Xiao W
Science immunology 2025 Dec 19;10(114):eadk0853
Science immunology 2025 Dec 19;10(114):eadk0853
Genetic deletion of TRPM8 channels restores microvascular function and mitigates chronic kidney disease progression.
Huang JW, Chen CH, Tsai MT, Hu PA, Guo BC, Chen WH, Chen HW, Lee TS, Tarng DC
Free radical biology & medicine 2025 Dec 16;241:659-670
Free radical biology & medicine 2025 Dec 16;241:659-670
Sappanone A Promotes Motor Function Recovery in Spinal Cord Injury Mice by Inhibiting Microglial M1 Polarization via Activation of the Keap1/Nrf2 Pathway.
Ren L, Chen Y, Xia J, Song X, Tao L, Li J, Xu L, Lü H, Hu J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Dec 15;39(23):e71298
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Dec 15;39(23):e71298
Fennel essential oil and its nanoemulsion modulate macrophage-mediated inflammatory responses and promote pressure ulcer healing.
Luo Z, Zeng L, Zhao Z, Zheng Y, Wan D
International immunopharmacology 2025 Dec 10;167:115631
International immunopharmacology 2025 Dec 10;167:115631
Circulating plasma exosomal miR-146b-5p regulates microglial-mediated neuroinflammation through the TRAF6/NF-κB signaling axis after intracerebral hemorrhage.
Zhang F, Han C, Chen J, Chen Z, Ding N, Zhang X, Zhao F, Zhang L, Wang P, Cao F, Hu R, Yao S
Life sciences 2025 Dec 1;382:124023
Life sciences 2025 Dec 1;382:124023
Cepharanthine alleviates lipopolysaccharide-induced acute lung injury through modulating macrophage polarization.
Dang L, He B, Yang J, Liu J, Ding Y, Xin W
Scientific reports 2025 Dec 1;16(1):538
Scientific reports 2025 Dec 1;16(1):538
Nebulized M2 macrophage-derived nanovesicles for the treatment of explosion-induced acute lung injury.
Tian L, Jin J, Lai F, Yao S, Zhang Y, Liu J, Zhang H, Lu Q, Liu C, Tian S, Lu Y, Liang Y, Zhao Y, Fan H, Ren W
Journal of colloid and interface science 2025 Aug;691:137381
Journal of colloid and interface science 2025 Aug;691:137381
GPR30 Inhibits Neuronal Apoptosis After Subarachnoid Hemorrhage by Activating the Wnt/β-Catenin Pathway in a m6A-dependent Manner.
Peng J, He J, Hu X, Xia Y
Molecular neurobiology 2025 Aug;62(8):9638-9650
Molecular neurobiology 2025 Aug;62(8):9638-9650
Aberrant neuronal excitation promotes neuroinflammation in the primary motor cortex of ischemic stroke mice.
Li TT, Guo XF, Zhao YJ, Cheng YH, Xin DQ, Song Y, Liu DX, Wang Z
Acta pharmacologica Sinica 2025 Aug;46(8):2105-2119
Acta pharmacologica Sinica 2025 Aug;46(8):2105-2119
Edaravone ameliorates inflammation in ischemic stroke mouse by regulating the CYP1A1 pathway through gut microbiota.
Zhang Y, Jiao X, Qi X, Wang G, Ma Y
Experimental neurology 2025 Aug;390:115263
Experimental neurology 2025 Aug;390:115263
Ethanol extract of Sauropus spatulifolius and its active constituents attenuate LPS-induced acute lung injury via NF-κB inhibition and Nrf2 activation.
Zhao L, Du L, Li Y, Guo Y, Pei D, Zhu D, Zhang H
Food science and biotechnology 2025 Aug;34(12):2947-2957
Food science and biotechnology 2025 Aug;34(12):2947-2957
Rescuing inflammatory microenvironment induced senescence via MgO immune mediated asymmetric short fibers for accelerating diabetic wound repair.
Chen Y, Liu Q, Guan J, Zheng C, Shi S, Zheng W, Guan J, Mao Y
Materials today. Bio 2025 Aug;33:102079
Materials today. Bio 2025 Aug;33:102079
Polyphenol-based self-assembled nanoparticles treating uveitis by inflammation-oxidative stress suppression.
Chen H, Yang Q, Li M, Ren M, Liu S, An G, Ren Y, Liu P, Du L, Sun X, Jin X
Materials today. Bio 2025 Aug;33:102052
Materials today. Bio 2025 Aug;33:102052
Alchemizing earth's legacy: Bismuth-engineered humic nanoparticles for IBD theranostics through mitochondrial anti-inflammation and sustained intestinal delivery.
Wang G, Wang Z, Liu L, Zhu Y, Zhong J, Zhang J, Wang L, Zheng C, Li W
Materials today. Bio 2025 Aug;33:101948
Materials today. Bio 2025 Aug;33:101948
Immunoregulatory function and anticancer effects of Polygonatum sibiricum polysaccharides against hepatic carcinoma via macrophage phenotype modulation.
Leng M, Jiang H, Lan H, Zhong W, Shi H, Jia J, Bao Y
International journal of biological macromolecules 2025 Aug;319(Pt 1):145423
International journal of biological macromolecules 2025 Aug;319(Pt 1):145423
Immunogenic cuproptosis in cancer immunotherapy via an in situ cuproptosis-inducing system.
Li J, Zhang G, Sun Z, Jiang M, Jia G, Liu H, Liu N, Shi L, Zhang L, Nie L, Zhang Y, Fu Y
Biomaterials 2025 Aug;319:123201
Biomaterials 2025 Aug;319:123201
Transcriptional responses to nitric oxide are widescale and source-dependent.
Schindler JC, Seth P, Premont RT, Stamler JS
The Journal of biological chemistry 2025 Aug;301(8):110476
The Journal of biological chemistry 2025 Aug;301(8):110476
Heparanase inhibition mitigates bleomycin-induced pulmonary fibrosis in mice by reducing M2 macrophage polarization.
He L, Lv Q, Luo J, Guo YD, Sun H, Zong M, Fan LY
Immunology letters 2025 Aug;274:107006
Immunology letters 2025 Aug;274:107006
A TRPV1 agonist from the transcriptome profiling of Dipsastraea rotumana inhibits neuroinflammation in vivo through the NF-κB and MAPK pathways.
Chen H, Xu N, Kam H, Zhao C, Chen Q, Fan G, Siu SWI, Wong CTT, Qiu JW, Cheung AK, Teixeira A, Rádis-Baptista G, Wong PK, Li S, Gong G, Lee SM
Pharmacological research 2025 Aug;218:107837
Pharmacological research 2025 Aug;218:107837
The Role of the cGAS/STING Pathway in Arsenic-Induced Neurotoxicity: Insights from the Crosstalk Between Astrocytes and Neurons.
Luo D, Sun B, Wang W, Zhang A
Biological trace element research 2025 Aug;203(8):4224-4239
Biological trace element research 2025 Aug;203(8):4224-4239
Black phosphorus nanosheets promote neuronal differentiation of neural stem cells through adhesion and pinocytosis for spinal cord injury repair.
Chen L, Shi L, Wei T, Liu H, Wang Z, Wang H, Li N, Feng S
Acta biomaterialia 2025 Aug;202:529-544
Acta biomaterialia 2025 Aug;202:529-544
SAA1 deletion ameliorates cardiac injury after myocardial infarction by promoting macrophage transformation to reparative subtype.
Xu Y, Zhang K, Sun C, Zhang Q, Li B, Yuan Y, Wang J, Zhang J, Chang Y, Wang S, Li J
Molecular immunology 2025 Aug;184:1-12
Molecular immunology 2025 Aug;184:1-12
β-Mangostin Attenuates TET2-Mediated DNA Demethylation of Prkcg in the Prevention of Intervertebral Disc Degeneration.
Kong X, Gu H, Zhang Y, Meng Q, Li Q, Song K, Li Y, Liu K, Liu Z, Hu R, Zhai H, Li T, Ling Z, Wei Z, Wei F, Cheng L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(32):e05077
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(32):e05077
Elevated Histone Lactylation Mediates Ferroptosis Resistance in Endometriosis Through the METTL3-Regulated HIF1A/HMOX1 Signaling Pathway.
Liang Z, Liu J, Gou Y, Wang H, Li Z, Cao Y, Zhang H, Bai R, Zhang Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(31):e08220
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(31):e08220
A prometabolite strategy inhibits cardiometabolic disease in an ApoE-/- murine model of atherosclerosis.
Beckman TN, Volpatti LR, Norton de Matos S, Slezak AJ, Reda JW, Weinstock A, Ziolkowski L, Turk A, Budina E, Cao S, Borjas G, Kwon JW, deLeon O, Refvik KC, Lauterbach AL, Gomes S, Chang EB, Hubbell JA
JCI insight 2025 Aug 8;10(15)
JCI insight 2025 Aug 8;10(15)
An Olsalazine-Loaded Hollow Mesoporous Prussian Blue/Polydopamine Nanozyme Alleviates Anxiety/Depression-like Behavior and Enhances Brain Neural Activity in Colitis Mice.
Luo Q, Liu D, Yang J, Li T, Sheng H, Liu S, Zhou X, Zhou C, Wang H, Wang Z, Ho CSH
ACS applied materials & interfaces 2025 Aug 6;17(31):44300-44318
ACS applied materials & interfaces 2025 Aug 6;17(31):44300-44318
ULK1 Knockout Exacerbates Ischemia-Induced Microglial Dysfunction via TRAF6/NF-κB Signaling Pathway.
Xiong Y, Li ZL, Wang XW, Li T, Cui MY, Wang MM, Fu YQ, Zheng Y, Xiang WW, Wang Y, Chen BH
ACS chemical neuroscience 2025 Aug 6;16(15):2978-2988
ACS chemical neuroscience 2025 Aug 6;16(15):2978-2988
Exosomal miR-218 secreted from endothelial progenitor cells mitigates acute lung injury in sepsis mice by inhibiting HMGA1 in alveolar macrophages.
Liang G, Zeng M, Wang Q, Wang W, Liu J, Gao M, He Z
Stem cell research & therapy 2025 Aug 6;16(1):431
Stem cell research & therapy 2025 Aug 6;16(1):431
Solidago decurrens Lour. controls LPS-induced acute lung injury by reducing inflammatory responses and modulating the TLR4/NF-κB/NLRP3 signaling pathway.
Ma DY, Peng LF, Gao XY, Xing TJ, Hao ZH
Journal of ethnopharmacology 2025 Aug 29;352:120172
Journal of ethnopharmacology 2025 Aug 29;352:120172
Piezo1 promotes colitis progression by modulating the Nrf2/NF-κB/NLRP3 signaling pathway.
Zhou P, Zeng L, Ma K, Li B, Zhang Y, Zhong Z, Wan Y, Tao K, Zhang P
Biochemical pharmacology 2025 Aug 29;242(Pt 1):117293
Biochemical pharmacology 2025 Aug 29;242(Pt 1):117293
The bone marrow mesenchymal stem cells derived migrasomes induced by Titania nanotubes surface serve as chemotaxis effect for osteogenesis.
Li G, Zhang Y, Wang H, Zhao Y, Liu K, Li Z, Meng M, He Y, Song W
Journal of nanobiotechnology 2025 Aug 29;23(1):592
Journal of nanobiotechnology 2025 Aug 29;23(1):592
Preventive and therapeutic effects of Tanshinone IIA on spinal cord injury without radiographic abnormality by regulating microglial phenotype polarization.
Xu L, Ma Y, Jiang G, Cao Z, Song J, Gao Y, Wang G, Fan J, Yang Y, Yu X
International immunopharmacology 2025 Aug 28;161:115086
International immunopharmacology 2025 Aug 28;161:115086
Harnessing dual-channel probiotics to synergistically correct intestinal and vaginal dysbiosis after antibiotic disruption.
Zhao X, Huang Q, Liu Y, He X, Chen W, Liu Y, Gan L, Wei J, Zhang H, Chen T
NPJ biofilms and microbiomes 2025 Aug 25;11(1):174
NPJ biofilms and microbiomes 2025 Aug 25;11(1):174
L-arginine synergistic with 5-fluorouracil intervenes in DNA damage repair via the DNA-PKcs/ATM/ATR pathway in hepatocellular carcinoma cells.
Wang H, Xie H, Lin Y, Zhang Z, Zhang M, Zhao J, Zhao Q, Liu L
Acta biochimica et biophysica Sinica 2025 Aug 22;58(3):621-637
Acta biochimica et biophysica Sinica 2025 Aug 22;58(3):621-637
Multiomics integration analysis identifies tumor cell-derived MIF as a therapeutic target and potentiates anti-PD-1 therapy in osteosarcoma.
Chen W, Liao Y, Yao H, Zou Y, Fang J, Zhang J, Guo Z, Tu J, Chen J, Huo Z, Wen L, Xie X
Journal for immunotherapy of cancer 2025 Aug 22;13(8)
Journal for immunotherapy of cancer 2025 Aug 22;13(8)
A Neutrophil Storage Pool in the Fetal Liver is the Principal Source of the Postnatal Neutrophil Surge.
Ishiwata R, Morimoto Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Aug 15;39(15):e70921
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Aug 15;39(15):e70921
Ergosterol from edible fungi: Enhancing fatty acid oxidation via CPT1A to protect against diabetic kidney disease.
Dong Z, Li X, Wang X, Xu J, Xu W
Food & function 2025 Aug 11;16(16):6599-6611
Food & function 2025 Aug 11;16(16):6599-6611
Functional anti-inflammatory mesoporous silica nanoplatform for Synergistic and Targeted abdominal aortic aneurysm treatment.
Wu Z, Wu X, Meng X, Lei J, Zeng C, Pu H, Liu Y, Xu Z, Wu X, Huang S, Qin J, Liu J, Lu X, Li B
Journal of colloid and interface science 2025 Apr;683(Pt 1):1040-1054
Journal of colloid and interface science 2025 Apr;683(Pt 1):1040-1054
Methylprednisolone Modulates the Tfr/Tfh ratio in EAE-Induced Neuroinflammation through the PI3K/AKT/FoxO1 and PI3K/AKT/mTOR Signalling Pathways.
Wu N, Zhao Y, Xiao M, Liu H, Chen H, Liu B, Wang X, Fan X
Inflammation 2025 Apr;48(2):950-962
Inflammation 2025 Apr;48(2):950-962
Efficacy of electro-acupuncture at "Weizhong" (BL40) on macrophage polarization in rats with injured lumbar multifidus.
Yuan T, He BU, Tieshan W, Dongliang Y, Wei Z, Tong L, Li Z, Zejun H
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2025 Apr;45(2):335-347
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2025 Apr;45(2):335-347
Kaempferol attenuates macrophage M1 polarization and liver fibrosis by inhibiting mitogen-activated protein kinase/nuclear factor κB signaling pathway.
Chen J, Liu H, Fu Y, Chen X, Zhang S, Yang Y, Li S, Wang G, Lan T
The Journal of pharmacology and experimental therapeutics 2025 Apr;392(4):103533
The Journal of pharmacology and experimental therapeutics 2025 Apr;392(4):103533
Baicalin attenuated metabolic dysfunction-associated fatty liver disease by suppressing oxidative stress and inflammation via the p62-Keap1-Nrf2 signalling pathway in db/db mice.
Liu WJ, Chen WW, Chen JY, Sun YB, Chang D, Wang CX, Xie JD, Lin W, Li SH, Xu W, Lin YX, Zheng YF, Zhou X, Huang MQ
Phytotherapy research : PTR 2025 Apr;39(4):1663-1678
Phytotherapy research : PTR 2025 Apr;39(4):1663-1678
Exosome-loaded tannic acid-thioctic acid hydrogel enhances wound healing in coagulation disorders.
Tu Y, Zheng W, Ding Z, Xiang J, Yang Q, Liu Y, Cao J, Shen Y, Tang Z, Lin S, Fan L, Xu Y, Chen B
Materials today. Bio 2025 Apr;31:101496
Materials today. Bio 2025 Apr;31:101496
An injectable responsive exosome-releasing hydrogel based on sodium alginate restores motor and bladder function by alleviating the injury microenvironment and facilitating distal nerve repair.
Lin Y, Guo Q, Liu Q, Wang W, Lv A, Zhang L, Li L, Gao J, Huang F
International journal of biological macromolecules 2025 Apr;304(Pt 1):140819
International journal of biological macromolecules 2025 Apr;304(Pt 1):140819
Lactoferrin-modified nanoemulsions enhance brain-targeting and therapeutic efficacy of arctigenin against Toxoplasma gondii-induced neuronal injury.
Lu JM, Jin GN, Xin Y, Ma JW, Shen XY, Quan YZ, Liu YM, Zhou JY, Wang BZ, Li YB, Xu X, Piao LX
International journal for parasitology. Drugs and drug resistance 2025 Apr;27:100575
International journal for parasitology. Drugs and drug resistance 2025 Apr;27:100575
Total alkaloids from Thesium chinense inhibit lipopolysaccharide-induced respiratory inflammation by modulating Nrf2/NF-κB/NLRP3 signaling pathway.
Li G, Guan Y, Xu L, Peng G, Han Q, Wang T, Xu Z, Wen X, Lou H, Shen T
Chinese journal of natural medicines 2025 Apr;23(4):421-430
Chinese journal of natural medicines 2025 Apr;23(4):421-430
Exploring the anti-inflammatory effects of Radix Curcumae essential oil in pulmonary sarcoidosis via the TLR4/MyD88/NF-κB pathway.
Mao Z, Lin X, Hu Y, Liu Y, Yu S, Zhou T, Zhang J, Yang X, Tian S, Miao M
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156496
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156496
ErTao decoction alleviates liver fibrosis by suppressing STING-mediated macrophages and NLRP3 inflammasome activation.
Jia H, Li J, Chen X, Liu Z, Wu C, Liu C, Zhang J, Luo M, Huang M, Huang S, Cai M, Gao L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156489
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156489
LIPUS Promotes Calcium Oscillation and Enhances Calcium Dependent Autophagy of Chondrocytes to Alleviate Osteoarthritis.
Guan M, Han X, Liao B, Han W, Chen L, Zhang B, Peng X, Tian Y, Xiao G, Li X, Kuang L, Zhu Y, Bai D
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(16):e2413930
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(16):e2413930
CpG-Based Nanovaccines Enhance Ovarian Cancer Immune Response by Gbp2-Mediated Remodeling of Tumor-Associated Macrophages.
Xiong J, Huang J, Xu H, Wu Q, Zhao J, Chen Y, Fan G, Guan H, Xiao R, He Z, Wu S, Ouyang W, Wang S, Zhang L, Xia P, Zhang W, Wu M
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(15):e2412881
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(15):e2412881
Reprogramming Lung Redox Homeostasis by NIR Driven Ultra-Small Pd Loaded Covalent Organic Framework Inhibits NF-κB Pathway for Acute Lung Injury Immunotherapy.
Lei D, Liao L, Qin T, Guan X, Duan K, Gao Z, Jin W, Yin M, Zhang K, Liu Y, Chen Y, Gao H, Li J, Huang F, Liu W, Xia C, Wang B, Huang H, Lv S, Zhi Q, Huang J, Gao M, Lu J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(14):e2413697
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(14):e2413697
Electret-Inspired Charge-Injected Hydrogel for Scar-Free Healing of Bacterially Infected Burns Through Bioelectrical Stimulation and Immune Modulation.
Liu M, Wang Y, Wang H, Qi L, Shang Y, Song J, Feng X, Chen Y, Memon WA, Shen Y, Wu X, Cao J, Zhao Y, Jiang Z, Liu D, Shafique S, Li S, Lu G, Wei Z, Liu Z, Zhou K, Quan Y, Zhang X, Zou X, Wang X, Liu N, Zhang Y, Hu Y, Han C, Wang W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(13):e2411889
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(13):e2411889
Hybrid membranes-mediated biomimetic-nanoparticle carrying miR-665 for effective tumor treatment by remodeling tumor microenvironment.
Zhang B, Zhang C, Chen C, Hong R, Shen Y, Yao C, Sun J, Zhang Y
International journal of pharmaceutics 2025 Apr 30;675:125479
International journal of pharmaceutics 2025 Apr 30;675:125479
Acid-resistant chemotactic DNA micromotors for probiotic delivery in inflammatory bowel disease.
Zhao Z, Xu Y, Hu Y
Nature communications 2025 Apr 22;16(1):3778
Nature communications 2025 Apr 22;16(1):3778
The E3 ligase c-Cbl modulates microglial phenotypes and contributes to Parkinson's disease pathology.
Deng S, Zhang Z, Liu L, Xu C, Zhang D, Dong L, Gao C, Wang X, Fan Z
Cell death discovery 2025 Apr 17;11(1):184
Cell death discovery 2025 Apr 17;11(1):184
Nicotinamide mononucleotide supplementation ameliorates testicular damage induced by ischemia-reperfusion through reshaping macrophage and neutrophil inflammatory properties.
Mou H, Zhang X, Ren F, Deng Y, Chi A, Zhan G, Li D, Sun Q, You W, Ge Y, Zhang M, Ju Z
International immunopharmacology 2025 Apr 16;152:114407
International immunopharmacology 2025 Apr 16;152:114407
Therapeutic potential of naturally derived carbon dots in sepsis-associated acute kidney injury.
Wang L, Li ZY, Zhong CL, Teng ZY, Wang B, Rehman A, Han LW, Zeng KW, Zhang JG, Lu ZY
Chinese medicine 2025 Apr 11;20(1):49
Chinese medicine 2025 Apr 11;20(1):49
Effect of Engineered Cyanobacterial Capsules on a Neurogenic Bladder after Spinal Cord Injury.
Xiao Y, He Y, Zhong D, Liu B, Tang Z, Lan X, Dong Y, Du H, Liu Y, Luo J
ACS nano 2025 Apr 1;19(12):11841-11860
ACS nano 2025 Apr 1;19(12):11841-11860
Vitamin D(3) alleviates intestinal injury in necrotizing enterocolitis and lipopolysaccharide-induced inflammatory response in dendritic cells in rats.
Ke B, Li C, Li S, Yan J, Sun L
Turkish journal of medical sciences 2024;54(5):1165-1174
Turkish journal of medical sciences 2024;54(5):1165-1174
Hollow Bismuth Nanoparticle-Loaded Gelatin Hydrogel Regulates M2 Polarization of Macrophages to Promote Infected Wound Healing.
Lv D, Xu Z, Yang H, Rong Y, Zhao Z, Hu Z, Yin R, Guo R, Cao X, Tang B
Biomaterials research 2024;28:0105
Biomaterials research 2024;28:0105
Breast cancer-derived CAV1 promotes lung metastasis by regulating integrin α6β4 and the recruitment and polarization of tumor-associated neutrophils.
Lin Q, Zong S, Wang Y, Zhou Y, Wang K, Shi F, Wang J, Feng M, Luo W, Zhang L, Lin H, Xiong L
International journal of biological sciences 2024;20(14):5695-5714
International journal of biological sciences 2024;20(14):5695-5714
N-Acetylcysteine Alleviates Depressive-Like Behaviors in Adolescent EAAC1(-/-) Mice and Early Life Stress Model Rats.
Kim HB, Kim YJ, Lee YJ, Yoo JY, Choi Y, Kim EM, Suh SW, Woo RS
International journal of biological sciences 2024;20(14):5450-5473
International journal of biological sciences 2024;20(14):5450-5473
Exosomal SLC16A1-AS1-induced M2 macrophages polarization facilitates hepatocellular carcinoma progression.
Hu Y, Li Y, Xiong H, Zhang Y, Wang F, Zhuo W, Zeng Z, Zhao Y, Wang H, Hu P, Han S, Huang Y, Lv G, Zhao G
International journal of biological sciences 2024;20(11):4341-4363
International journal of biological sciences 2024;20(11):4341-4363
Antioxidant Carbon Dots and Ursolic Acid Co-Encapsulated Liposomes Composite Hydrogel for Alleviating Adhesion Formation and Enhancing Tendon Healing in Tendon Injury.
Peng C, Kang S, Jiang M, Yang M, Gong X
International journal of nanomedicine 2024;19:8709-8727
International journal of nanomedicine 2024;19:8709-8727
Sphingosine Kinase 1 Aggravates Liver Fibrosis by Mediating Macrophage Recruitment and Polarization.
Ding X, Zhang X, Cao J, Chen S, Chen Y, Yuan K, Chen B, Yang G, Li S, Yang J, Wang G, Tacke F, Lan T
Cellular and molecular gastroenterology and hepatology 2024;18(6):101406
Cellular and molecular gastroenterology and hepatology 2024;18(6):101406
The Therapeutic Potential of Pristimerin in Osteoarthritis: Mechanistic Insights from in vitro and in vivo Studies.
Yin L, Fan Y, Zhong X, Meng X, He Z, Hong Z, Chen J, Zhang Q, Kong M, Wang J, Tong Y, Bi Q
Drug design, development and therapy 2024;18:5445-5459
Drug design, development and therapy 2024;18:5445-5459
Chuanxiong Renshen Decoction Inhibits Alzheimer's Disease Neuroinflammation by Regulating PPARγ/NF-κB Pathway.
Hou J, Wang X, Zhang J, Shen Z, Li X, Yang Y
Drug design, development and therapy 2024;18:3209-3232
Drug design, development and therapy 2024;18:3209-3232
Probucol mitigates high-fat diet-induced cognitive and social impairments by regulating brain redox and insulin resistance.
Wu HM, Yang YV, Huang NJ, Fan LP, Dai YY, Hu KT, Tang TY, Liu L, Xu Y, Liu DT, Cai ZX, Niu XY, Ren XY, Yao ZH, Qin HY, Chen JZ, Huang X, Zhang C, You X, Wang C, He Y, Hong W, Sun YX, Zhan YH, Lin SY
Frontiers in neuroscience 2024;18:1368552
Frontiers in neuroscience 2024;18:1368552
IRF2 Affects LPS- and IFN-γ-Induced Pro-Inflammatory Responses, Cell Viability, Migration and Apoptosis of Macrophages by Regulating IRG1.
Qin RX, Ma XY, Han ZY, Ma SY, Shen ZJ, Lu ZH, Sun Y, Yu WL
Journal of inflammation research 2024;17:9651-9664
Journal of inflammation research 2024;17:9651-9664
Nrf2 Deficiency Exacerbates Parkinson's Disease by Aggravating NLRP3 Inflammasome Activation in MPTP-Induced Mouse Models and LPS-Induced BV2 Cells.
Lu R, Zhou X, Zhang L, Hao M, Yang X
Journal of inflammation research 2024;17:6277-6295
Journal of inflammation research 2024;17:6277-6295
New Insights into Roles of IL-7R Gene as a Therapeutic Target Following Intracerebral Hemorrhage.
Cui J, Wang H, Liu S, Zhao Y
Journal of inflammation research 2024;17:399-415
Journal of inflammation research 2024;17:399-415
The role of the C5a-C5aR pathway in iron metabolism and gastric cancer progression.
Ni Q, Yang H, Rao H, Zhang L, Xiong M, Han X, Deng B, Wang L, Chen J, Shi Y
Frontiers in immunology 2024;15:1522181
Frontiers in immunology 2024;15:1522181
Assembly of ceria-Nrf2 nanoparticles as macrophage-targeting ROS scavengers protects against myocardial infarction.
Liao W, Lin J, Wang W, Zhang M, Chen Y, Li X, Liu H, Wang PX, Zhao G, Fu J, Wu X
Frontiers in pharmacology 2024;15:1503757
Frontiers in pharmacology 2024;15:1503757
Protective effects of berbamine against arginase-1 deficiency-induced injury in human brain microvascular endothelial cells.
Wei X, Li W, Chen Z, Chen J, Chen Y, Cai J, Lin H
Frontiers in pharmacology 2024;15:1497973
Frontiers in pharmacology 2024;15:1497973
Neuron stress-related genes serve as new biomarkers in hypothalamic tissue following high fat diet.
Liang C, Lu H, Wang X, Su J, Qi F, Shang Y, Li Y, Zhang D, Duan C
Frontiers in endocrinology 2024;15:1443880
Frontiers in endocrinology 2024;15:1443880
L-arginine combination with 5-fluorouracil inhibit hepatocellular carcinoma cells through suppressing iNOS/NO/AKT-mediated glycolysis.
Hu Y, Xing Y, Fan G, Xie H, Zhao Q, Liu L
Frontiers in pharmacology 2024;15:1391636
Frontiers in pharmacology 2024;15:1391636
Quercetin ameliorates ulcerative colitis by restoring the balance of M2/M1 and repairing the intestinal barrier via downregulating cGAS‒STING pathway.
Gao F, Zhu F, Shuai B, Wu M, Wei C, Yuan Y, Gui Y, Tian Y, Fan H, Wu H
Frontiers in pharmacology 2024;15:1351538
Frontiers in pharmacology 2024;15:1351538
Circular RNA SCMH1 suppresses KMO expression to inhibit mitophagy and promote functional recovery following stroke.
Wang Y, Bai Y, Cai Y, Zhang Y, Shen L, Xi W, Zhou Z, Xu L, Liu X, Han B, Yao H
Theranostics 2024;14(19):7292-7308
Theranostics 2024;14(19):7292-7308
Neutrophil-like pH-responsive pro-efferocytic nanoparticles improve neurological recovery by promoting erythrophagocytosis after intracerebral hemorrhage.
Fan L, Jin L, Tang T, Zheng Y, Chen Z, Lin H, Ding C, Wang T, Chen H, Guo Y, Xu C, Zhou H, Wu X, Fu X, Yan F, Mao Z, Chen G
Theranostics 2024;14(1):283-303
Theranostics 2024;14(1):283-303
Genetically engineered electrospinning contributes to spinal cord injury repair by regulating the immune microenvironment.
Sun Y, Wu J, Zhou L, Wang W, Wang H, Sun S, Xu Y, Zhang L, Jiang X, Zhu G, Xi K, Gu Y, Chen L
Frontiers in bioengineering and biotechnology 2024;12:1415527
Frontiers in bioengineering and biotechnology 2024;12:1415527
Inhibition of PTEN promotes osteointegration of titanium implants in type 2 diabetes by enhancing anti-inflammation and osteogenic capacity of adipose-derived stem cells.
Zhang G, Song S, Chen Z, Liu X, Zheng J, Wang Y, Chen X, Song Y
Frontiers in bioengineering and biotechnology 2024;12:1358802
Frontiers in bioengineering and biotechnology 2024;12:1358802
Dandelion-shaped strontium-gallium microparticles for the hierarchical stimulation and comprehensive regulation of wound healing.
Ji M, Yuan Z, Ma H, Feng X, Ye C, Shi L, Chen X, Han F, Zhao C
Regenerative biomaterials 2024;11:rbae121
Regenerative biomaterials 2024;11:rbae121
Low-Dose LPS Modulates Microglia/Macrophages Phenotypic Transformation to Amplify Rehabilitation Effects in Chronic Spinal Cord Injured (CSCI) Mice.
Zhong J, He Y, Zhao Q, Luo H, Zhang Q, Tian Y, Liu Y, Yang C, Yin Y, Yu L, Pan L, Tan B
Molecular neurobiology 2024 Sep;61(9):6484-6500
Molecular neurobiology 2024 Sep;61(9):6484-6500
Mer activation ameliorates nerve injury-induced neuropathic pain by regulating microglial polarization and neuroinflammation via SOCS3 in male rats.
Wang J, Zhu X, Wu Y
Naunyn-Schmiedeberg's archives of pharmacology 2024 Sep;397(9):7037-7050
Naunyn-Schmiedeberg's archives of pharmacology 2024 Sep;397(9):7037-7050
Delivery of neurotrophin-3 by RVG-Lamp2b-modified mesenchymal stem cell-derived exosomes alleviates facial nerve injury.
Bi W, Mu X, Li Y, Sun Q, Xiang L, Hu M, Liu H
Human cell 2024 Sep;37(5):1378-1393
Human cell 2024 Sep;37(5):1378-1393
Naringenin relieves paclitaxel-induced pain by suppressing calcitonin gene-related peptide signalling and enhances the anti-tumour action of paclitaxel.
Pan C, Xu Y, Jiang Z, Fan C, Chi Z, Zhang Y, Miao M, Ren Y, Wu Z, Xu L, Mei C, Chen Q, Xi Y, Chen X
British journal of pharmacology 2024 Sep;181(17):3136-3159
British journal of pharmacology 2024 Sep;181(17):3136-3159
Sestrin2 remedies neuroinflammatory response by inhibiting A1 astrocyte conversion via autophagy.
Pan Z, Yu X, Wang W, Shen K, Chen J, Zhang Y, Huang R
Journal of neurochemistry 2024 Sep;168(9):2640-2653
Journal of neurochemistry 2024 Sep;168(9):2640-2653
Oxysophoridine inhibits oxidative stress and inflammation in hepatic fibrosis via regulating Nrf2 and NF-κB pathways.
Chen JY, Yang YJ, Meng XY, Lin RH, Tian XY, Zhang Y, Lai WF, Yang C, Ma XQ, Huang MQ
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155585
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155585
Wheel-Running Exercise Alleviates Anxiety-Like Behavior via Down-Regulating S-Nitrosylation of Gephyrin in the Basolateral Amygdala of Male Rats.
Yang PF, Nie TL, Sun XN, Xu LX, Ma C, Wang F, Long LH, Chen JG
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Sep;11(34):e2400205
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Sep;11(34):e2400205
Isoquercetin Ameliorates Osteoarthritis via Nrf2/NF-κB Axis: An In Vitro and In Vivo Study.
Yu H, Lou J, Ni L, Yan M, Zhu K, Mao S, Zhu J
Chemical biology & drug design 2024 Sep;104(3):e14620
Chemical biology & drug design 2024 Sep;104(3):e14620
Transcription factor EGR2 alleviates autoimmune uveitis via activation of GDF15 to modulate the retinal microglial phenotype.
Li W, He S, Tan J, Li N, Zhao C, Wang X, Zhang Z, Liu J, Huang J, Li X, Zhou Q, Hu K, Yang P, Hou S
Proceedings of the National Academy of Sciences of the United States of America 2024 Sep 24;121(39):e2316161121
Proceedings of the National Academy of Sciences of the United States of America 2024 Sep 24;121(39):e2316161121
A composite patch loaded with 2-Deoxy Glucose facilitates cardiac recovery after myocardial infarction via attenuating local inflammatory response.
Xiao W, Zhu Z, Yu Z, Pan Y, Xue Q, Zhou Y, Shi J
Scientific reports 2024 Sep 2;14(1):20368
Scientific reports 2024 Sep 2;14(1):20368
Allantoin ameliorates dopaminergic neuronal damage in MPTP-induced Parkinson's disease mice via regulating oxidative damage, inflammation, and gut microbiota disorder.
Yang S, Sun X, Liu D, Zhang Y, Gao X, He J, Cui M, Fu S, He D
Food & function 2024 Sep 16;15(18):9390-9408
Food & function 2024 Sep 16;15(18):9390-9408
Dietary nitrate maintains homeostasis of oxidative stress and gut microbiota to promote flap survival in type 2 diabetes mellitus rats.
Niu Q, Li D, Guo W, Feng Z, Han Z, Yang Y
BMC endocrine disorders 2024 Sep 10;24(1):184
BMC endocrine disorders 2024 Sep 10;24(1):184
Hypoxic microenvironment promotes diabetic wound healing by polarizing macrophages to the M2 phenotype in vivo.
Cai F, Wang P, Yuan M, Chen W, Liu Y
Journal of molecular histology 2024 Oct;55(5):967-976
Journal of molecular histology 2024 Oct;55(5):967-976
Mesenchymal Stem Cells Regulate Microglial Polarization via Inhibition of the HMGB1/TLR4 Signaling Pathway in Diabetic Retinopathy.
Tong J, Yao G, Chen Y, Xie H, Zheng X, Sun L, Huang Z, Xie Z
Inflammation 2024 Oct;47(5):1728-1743
Inflammation 2024 Oct;47(5):1728-1743
Targeting Mitochondrial Oxidative Stress to Protect Against Preterm Birth and Fetal Brain Injury via Nrf2 Induction.
Chen C, Zhu S, Fu T, Chen Y, Bai L, Chen D
Antioxidants & redox signaling 2024 Oct;41(10-12):597-615
Antioxidants & redox signaling 2024 Oct;41(10-12):597-615
Sequential Targeted Enzyme-Instructed Self-Assembly Supramolecular Nanofibers to Attenuate Intervertebral Disc Degeneration.
Liu Y, Sun X, Wang L, Dou Y, Tian Y, Yu T, Zhang Y, Zhao Q, Lu J, Feng Y, Wang J, Liu X, Shang Y, Li C, Yang Q
Advanced materials (Deerfield Beach, Fla.) 2024 Oct;36(41):e2408678
Advanced materials (Deerfield Beach, Fla.) 2024 Oct;36(41):e2408678
Dehydrocostus Lactone Ameliorates LPS-Induced Acute Lung Injury by Inhibiting PFKFB3-Mediated Glycolysis.
Li Y, Wang X, Zhao L, Pan B, Xu X, Zhu D
Journal of cellular biochemistry 2024 Oct;125(10):e30639
Journal of cellular biochemistry 2024 Oct;125(10):e30639
Bioactivity-Oriented Separation of "Pepper Alkaloids" from Piper sintenense Hatusima with Potential Antigouty Arthritis Activity.
Yao Z, Li T, Jin M, Fang S, Wang J, Zheng J, Pan K, Zhang J, Zhao G, Yin Z, Huang Y
Journal of agricultural and food chemistry 2024 Oct 30;72(43):23979-23990
Journal of agricultural and food chemistry 2024 Oct 30;72(43):23979-23990
Mutation of Pseudomonas aeruginosa lasI/rhlI diminishes its cytotoxicity, oxidative stress, inflammation, and apoptosis on THP-1 macrophages.
Ren Y, You X, Zhu R, Li D, Wang C, He Z, Hu Y, Li Y, Liu X, Li Y
Microbiology spectrum 2024 Oct 3;12(10):e0414623
Microbiology spectrum 2024 Oct 3;12(10):e0414623
Erjingpill bionic cerebrospinal fluid alleviates LPS-induced inflammatory response in BV2 cells by inhibiting glycolysis via mTOR.
Wang S, Wu L, Xie Y, Ge S, Wu Y, Chen L, Yi L, Yang J, Duan F, Huang L
Journal of ethnopharmacology 2024 Oct 28;333:118412
Journal of ethnopharmacology 2024 Oct 28;333:118412
ACOD1 mediates Staphylococcus aureus-induced inflammatory response via the TLR4/NF-κB signaling pathway.
Dai F, Zhang X, Ma G, Li W
International immunopharmacology 2024 Oct 25;140:112924
International immunopharmacology 2024 Oct 25;140:112924
Morin alleviates DSS-induced ulcerative colitis in mice via inhibition of inflammation and modulation of intestinal microbiota.
Qiu L, Yan C, Yang Y, Liu K, Yin Y, Zhang Y, Lei Y, Jia X, Li G
International immunopharmacology 2024 Oct 25;140:112846
International immunopharmacology 2024 Oct 25;140:112846
Leukocyte infiltration and cross-talk with cardiomyocytes exploit intracellular stress pathways in dilated cardiomyopathy of idiopathic origin.
Talukdar D, Haldar AK, Kumar S, Dastidar R, Basu A, Roy A, Sarkar S, Dey S, Sikder K
Molecular biology reports 2024 Oct 24;51(1):1090
Molecular biology reports 2024 Oct 24;51(1):1090
Ouabain Ameliorates Alzheimer's Disease-Associated Neuropathology and Cognitive Impairment in FAD(4T) Mice.
Wang D, Liu J, Zhu Q, Wei X, Zhang X, Chen Q, Zhao Y, Tang H, Xu W
Nutrients 2024 Oct 20;16(20)
Nutrients 2024 Oct 20;16(20)
Oxygen Glucose Deprivation-Induced Lactylation of H3K9 Contributes to M1 Polarization and Inflammation of Microglia Through TNF Pathway.
He L, Yin R, Hang W, Han J, Chen J, Wen B, Chen L
Biomedicines 2024 Oct 17;12(10)
Biomedicines 2024 Oct 17;12(10)
Intermittent fasting attenuates cognitive dysfunction and systemic disease activity in mice with neuropsychiatric systemic lupus erythematosus.
Feng Y, Qin J, Wang P, Lai Y, Tang L, Zhang X, Ren H, Yang M, Huang Q
Life sciences 2024 Oct 15;355:122999
Life sciences 2024 Oct 15;355:122999
Peptide TaY Attenuates Inflammatory Responses by Interacting with Myeloid Differentiation 2 and Inhibiting NF-κB Signaling Pathway.
Wang J, Zhou Y, Zhang J, Tong Y, Abbas Z, Zhao X, Li Z, Zhang H, Chen S, Si D, Zhang R, Wei X
Molecules (Basel, Switzerland) 2024 Oct 13;29(20)
Molecules (Basel, Switzerland) 2024 Oct 13;29(20)
LysoPE mediated by respiratory microorganism Aeromicrobium camelliae alleviates H9N2 challenge in mice.
Yan Q, Xing J, Zou R, Sun M, Zou B, Wang Y, Niu T, Yu T, Huang H, Yang W, Shi C, Yang G, Wang C
Veterinary research 2024 Oct 11;55(1):136
Veterinary research 2024 Oct 11;55(1):136
Crystalline silica-induced endoplasmic reticulum stress promotes the pathogenesis of silicosis by augmenting proinflammatory interstitial pulmonary macrophages.
Yuan H, He Y, Zhang Y, Min H, Chen J, Li C
The Science of the total environment 2024 Oct 10;946:174299
The Science of the total environment 2024 Oct 10;946:174299
Vitexin Inhibits TNBC Progression and Metastasis by Modulating Macrophage Polarization Through EGFR Signaling.
Lin Y, Li L, Huang H, Wen X, Zhang Y, Zhang R, Huang W
Journal of immunotherapy (Hagerstown, Md. : 1997) 2024 Oct 1;47(8):303-312
Journal of immunotherapy (Hagerstown, Md. : 1997) 2024 Oct 1;47(8):303-312
Silencing ARL11 relieved atherosclerotic inflammation and lipid deposition via retraining JAK2/STAT1 pathway.
Zhen Y, Yang J, Song J, Xing Z, Zheng J
Atherosclerosis 2024 Nov;398:118564
Atherosclerosis 2024 Nov;398:118564
The role of phlorizin liposome-embedded oxidized sodium alginate/carboxymethyl chitosan in diabetic wound healing.
Wu X, Ding C, Liu X, Ding Q, Zhang S, Wang Y, Xin C, Wei H, Mao R, Zhang G, Zhao T, Liu W
International journal of biological macromolecules 2024 Nov;279(Pt 3):135324
International journal of biological macromolecules 2024 Nov;279(Pt 3):135324
An Engineered Hierarchical Hydrogel with Immune Responsiveness and Targeted Mitochondrial Transfer to Augmented Bone Regeneration.
Cai W, Mao S, Wang Y, Gao B, Zhao J, Li Y, Chen Y, Zhang D, Yang J, Yang G
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Nov;11(42):e2406287
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Nov;11(42):e2406287
Taurine Inhibits Lung Metastasis in Triple-Negative Breast Cancer by Modulating Macrophage Polarization Through PTEN-PI3K/Akt/mTOR Pathway.
Lin Y, Huang Y, Zheng Y, Chen W, Zhang Y, Yang Y, Huang W
Journal of immunotherapy (Hagerstown, Md. : 1997) 2024 Nov-Dec 01;47(9):369-377
Journal of immunotherapy (Hagerstown, Md. : 1997) 2024 Nov-Dec 01;47(9):369-377
Hexokinase 2 senses fructose in tumor-associated macrophages to promote colorectal cancer growth.
Yan H, Wang Z, Teng D, Chen X, Zhu Z, Chen H, Wang W, Wei Z, Wu Z, Chai Q, Zhang F, Wang Y, Shu K, Li S, Shi G, Zhu M, Piao HL, Shen X, Bu P
Cell metabolism 2024 Nov 5;36(11):2449-2467.e6
Cell metabolism 2024 Nov 5;36(11):2449-2467.e6
Protective Effects of L-Cysteine Against Cisplatin-Induced Oxidative Stress-Mediated Reproductive Damage.
Chiang YF, Chen YT, Huang KC, Hung WL, Chung CP, Shieh TM, Huang YJ, Ali M, Hsia SM
Antioxidants (Basel, Switzerland) 2024 Nov 23;13(12)
Antioxidants (Basel, Switzerland) 2024 Nov 23;13(12)
Mesenchymal stromal cells deliver H(2)S-enhanced Nrf2 via extracellular vesicles to mediate mitochondrial homeostasis for repairing hypoxia-ischemia brain damage.
Gai C, Li T, Zhao Y, Cheng Y, Song Y, Luo Q, Liu D, Wang Z
Free radical biology & medicine 2024 Nov 20;225:528-545
Free radical biology & medicine 2024 Nov 20;225:528-545
Biliverdin improved angiogenesis and suppressed apoptosis via PI3K/Akt-mediated Nrf2 antioxidant system to promote ischemic flap survival.
Yao Z, Xue K, Chen J, Zhang Y, Zhang G, Zheng Z, Li Z, Li Z, Wang F, Sun X, Shen L, Mao C, Lin C
Free radical biology & medicine 2024 Nov 20;225:35-52
Free radical biology & medicine 2024 Nov 20;225:35-52
Exploring the role of iNOS in HFpEF-Related myocardial fibrosis: Involvement of PTEN-PI3K/AKT signaling pathway.
You H, Gou Q, Dong M, Chang F, Xiu J
Biochemical and biophysical research communications 2024 Nov 19;734:150589
Biochemical and biophysical research communications 2024 Nov 19;734:150589
HMGB1 Modulates Macrophage Metabolism and Polarization in Ulcerative Colitis by Inhibiting Cpt1a Expression.
Wang F, Luo L, Wu Z, Wan L, Li F, Wen Z
Frontiers in bioscience (Landmark edition) 2024 Nov 19;29(11):387
Frontiers in bioscience (Landmark edition) 2024 Nov 19;29(11):387
Compound (E)-2-(3,4-dihydroxystyryl)-3-hydroxy-4H-pyran-4-one downregulation of Galectin-3 ameliorates Aβ pathogenesis-induced neuroinflammation in 5 × FAD mice.
Liu X, Chen P, Wu W, Zhong M, Dong S, Lin H, Dai C, Zhang Z, Lin S, Che C, Xu J, Li C, Li H, Pan X, Chen Z, Chen X, Ye ZC
Life sciences 2024 Nov 15;357:123085
Life sciences 2024 Nov 15;357:123085
Astragaloside IV promotes cerebral tissue restoration through activating AMPK- mediated microglia polarization in ischemic stroke rats.
Li MC, Jia JT, Wang YX, Zhuang YM, Wang HY, Lin ZY, Lu Y, Li MZ, Wang ZJ, Zhao H
Journal of ethnopharmacology 2024 Nov 15;334:118532
Journal of ethnopharmacology 2024 Nov 15;334:118532
Phillyrin: A potential therapeutic agent for osteoarthritis via modulation of NF-κB and Nrf2 signaling pathways.
Ma J, Wang Z, Sun Y, Zheng R, Tan H, Zhang H, Jin Z, Wu Y, Sun Z
International immunopharmacology 2024 Nov 15;141:112960
International immunopharmacology 2024 Nov 15;141:112960
PLGA microspheres carrying EMSCs-CM for the effective treatment of murine ulcerative colitis.
Yang W, Zhang X, Wang Z, Zheng X, Wu W, Chen Q
International immunopharmacology 2024 Nov 15;141:112883
International immunopharmacology 2024 Nov 15;141:112883
STING orchestrates microglia polarization via interaction with LC3 in autophagy after ischemia.
Kong L, Xu P, Shen N, Li W, Li R, Tao C, Wang G, Zhang Y, Sun W, Hu W, Liu X
Cell death & disease 2024 Nov 13;15(11):824
Cell death & disease 2024 Nov 13;15(11):824
Diquat exacerbates oxidative stress and neuroinflammation by blocking the autophagic flux of microglia in the hippocampus.
Wang P, Song CY, Lu X, Zhou JN, Lin LY, Li T, Zhang Q, Lu YQ
Ecotoxicology and environmental safety 2024 Nov 1;286:117188
Ecotoxicology and environmental safety 2024 Nov 1;286:117188
Treatment of silicosis with quercetin depolarizing macrophages via inhibition of mitochondrial damage-associated pyroptosis.
Xiao CY, Tang Y, Ren T, Kong C, You H, Bai XF, Huang Q, Chen Y, Li LG, Liu MY, Leng F, Han N, Li TF, Wang MF
Ecotoxicology and environmental safety 2024 Nov 1;286:117161
Ecotoxicology and environmental safety 2024 Nov 1;286:117161
Macrophage M2 polarization promotes pulpal inflammation resolution during orthodontic tooth movement.
Li J, Ren H, Zhang Z, Zhang J, Wei F
Journal of cellular and molecular medicine 2024 May;28(9):e18350
Journal of cellular and molecular medicine 2024 May;28(9):e18350
Early postnatal moderate catch‑up growth in rats with nutritional intrauterine growth restriction preserves pulmonary vascular and cognitive function in adulthood.
Ye L, Huang Y, Chen K, Hang C, Ying Y, Zu L, Luo X, Du L
Experimental and therapeutic medicine 2024 May;27(5):183
Experimental and therapeutic medicine 2024 May;27(5):183
Polarization to M1-type microglia in the hippocampus is involved in depression-like behavior in a mouse model of olfactory dysfunction.
Takahashi K, Tsuji M, Nakagawasai O, Katsuyama S, Miyagawa K, Kurokawa K, Mochida-Saito A, Takeda H, Tadano T
Neurochemistry international 2024 May;175:105723
Neurochemistry international 2024 May;175:105723
Upregulation of Nrf2 signaling: A key molecular mechanism of Baicalin's neuroprotective action against diabetes-induced cognitive impairment.
Zheng Y, Wang C, Liu W, Chen J, Sun Y, Chang D, Wang H, Xu W, Lu JJ, Zhou X, Huang M
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116579
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116579
3D Printing of a Vascularized Mini-Liver Based on the Size-Dependent Functional Enhancements of Cell Spheroids for Rescue of Liver Failure.
Zhang J, Chen X, Chai Y, Zhuo C, Xu Y, Xue T, Shao D, Tao Y, Li M
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 May;11(17):e2309899
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 May;11(17):e2309899
The Sirtuin 5 Inhibitor MC3482 Ameliorates Microglia‑induced Neuroinflammation Following Ischaemic Stroke by Upregulating the Succinylation Level of Annexin-A1.
Xia Q, Yu Y, Zhan G, Zhang X, Gao S, Han T, Zhao Y, Li X, Wang Y
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2024 May 8;19(1):17
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2024 May 8;19(1):17
Protective Effects of an Oligo-Fucoidan-Based Formula against Osteoarthritis Development via iNOS and COX-2 Suppression following Monosodium Iodoacetate Injection.
Chiang YF, Huang KC, Wang KL, Huang YJ, Chen HY, Ali M, Shieh TM, Hsia SM
Marine drugs 2024 May 6;22(5)
Marine drugs 2024 May 6;22(5)
IGF2BP2 regulates the inflammation of fibroblast-like synoviocytes via GSTM5 in rheumatoid arthritis.
Nan Y, Chen M, Wu W, Huang R, Sun W, Lu Q, Gu Z, Mao X, Xu H, Wang Y
Cell death discovery 2024 May 3;10(1):215
Cell death discovery 2024 May 3;10(1):215
Resveratrol-loaded sulfated Hericium erinaceus β-glucan-chitosan nanoparticles: Preparation, characterization and synergistic anti-inflammatory effects.
Zhang Z, Ge M, Wu D, Li W, Chen W, Liu P, Zhang H, Yang Y
Carbohydrate polymers 2024 May 15;332:121916
Carbohydrate polymers 2024 May 15;332:121916
S100A12 is involved in the pathology of osteoarthritis by promoting M1 macrophage polarization via the NF-κB pathway.
Zhang Y, Li Z, Chen C, Wei W, Li Z, Huang H, Zhou H, He W, Xia J, Li B, Yang Y
Connective tissue research 2024 Mar;65(2):133-145
Connective tissue research 2024 Mar;65(2):133-145
Inhibiting the NLRP3 Inflammasome with MCC950 Alleviates Neurological Impairment in the Brain of EAE Mice.
Hou B, Yin J, Liu S, Guo J, Zhang B, Zhang Z, Yang L, Tan X, Long Y, Feng S, Zhou J, Wu Y, Wang X, Han S, Wang Z, He X
Molecular neurobiology 2024 Mar;61(3):1318-1330
Molecular neurobiology 2024 Mar;61(3):1318-1330
Quercetin-3-O-β-D-glucuronide attenuates osteoarthritis by inhibiting cartilage extracellular matrix degradation and inflammation.
Mao H, Feng Y, Feng J, Yusufu Y, Sun M, Yang L, Jiang Q
Journal of orthopaedic translation 2024 Mar;45:236-246
Journal of orthopaedic translation 2024 Mar;45:236-246
A potential mechanism clue to the periodic storm from microglia activation and progressive neuron damage induced by paraquat exposure.
Shi G, Zhang C, Bai X, Sun J, Wang K, Meng Q, Li Y, Hu G, Hu R, Cai Q, Huang M
Environmental toxicology 2024 Mar;39(3):1874-1888
Environmental toxicology 2024 Mar;39(3):1874-1888
Hippocampal and gut AMPK activation attenuates enterocolitis-like symptoms and co-occurring depressive-like behavior in ulcerative colitis model mice: Involvement of brain-gut autophagy.
Takahashi K, Kurokawa K, Hong L, Miyagawa K, Mochida-Saito A, Takeda H, Tsuji M
Experimental neurology 2024 Mar;373:114671
Experimental neurology 2024 Mar;373:114671
A Biomimetic Se-nHA/PC Composite Microsphere with Synergistic Immunomodulatory and Osteogenic Ability to Activate Bone Regeneration in Periodontitis.
Ming P, Liu Y, Yu P, Jiang X, Yuan L, Cai S, Rao P, Cai R, Lan X, Tao G, Xiao J
Small (Weinheim an der Bergstrasse, Germany) 2024 Mar;20(9):e2305490
Small (Weinheim an der Bergstrasse, Germany) 2024 Mar;20(9):e2305490
Radix Bupleuri aqueous extract attenuates MK801-induced schizophrenia-like symptoms in mice: Participation of intestinal flora.
Yang P, Huang S, Luo Z, Zhou S, Zhang C, Zhu Y, Yang J, Li L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Mar;172:116267
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Mar;172:116267
Bredigite-Based Bioactive Nerve Guidance Conduit for Pro-Healing Macrophage Polarization and Peripheral Nerve Regeneration.
Xuan Y, Li L, Yin X, He D, Li S, Zhang C, Yin Y, Xu W, Zhang Z
Advanced healthcare materials 2024 Mar;13(8):e2302994
Advanced healthcare materials 2024 Mar;13(8):e2302994
Flexible Organic Photovoltaic-Powered Hydrogel Bioelectronic Dressing With Biomimetic Electrical Stimulation for Healing Infected Diabetic Wounds.
Hu YW, Wang YH, Yang F, Liu DX, Lu GH, Li ST, Wei ZX, Shen X, Jiang ZD, Zhao YF, Pang Q, Song BY, Shi ZW, Shafique S, Zhou K, Chen XL, Su WM, Jian JW, Tang KQ, Liu TL, Zhu YB
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Mar;11(10):e2307746
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Mar;11(10):e2307746
Boosting Microglial Lipid Metabolism via TREM2 Signaling by Biomimetic Nanoparticles to Attenuate the Sevoflurane-Induced Developmental Neurotoxicity.
Li W, Meng X, Peng K, Han Y, Liu H, Zhao W, Wang G, Deng L, Liu H, Li Z, Ji F
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Mar;11(10):e2305989
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Mar;11(10):e2305989
LDL-Binding IL-10 Reduces Vascular Inflammation in Atherosclerotic Mice.
Volpatti LR, de Matos SN, Borjas G, Reda J, Watkins EA, Zhou Z, Nguyen M, Solanki A, Fang Y, Hubbell JA
bioRxiv : the preprint server for biology 2024 Mar 6;
bioRxiv : the preprint server for biology 2024 Mar 6;
The Effect of Salvianolic Acid A on Tumor-Associated Macrophage Polarization and Its Mechanisms in the Tumor Microenvironment of Triple-Negative Breast Cancer.
Tang C, Jiang ST, Li CX, Jia XF, Yang WL
Molecules (Basel, Switzerland) 2024 Mar 26;29(7)
Molecules (Basel, Switzerland) 2024 Mar 26;29(7)
A novel microglia-targeting strategy based on nanoparticle-mediated delivery of miR-26a-5p for long-lasting analgesia in chronic pain.
Lu Y, Liu S, Wang P, Guo X, Qin Z, Hou H, Tao T
Journal of nanobiotechnology 2024 Mar 23;22(1):128
Journal of nanobiotechnology 2024 Mar 23;22(1):128
Cluster of Differentiation-44-Targeting Prussian Blue Nanoparticles Onloaded with Colchicine for Atherosclerotic Plaque Regression in a Mice Model.
Zhu Y, Fang Y, Wang Y, Han D, Liu J, Tian L, Xu M, Wang Y, Cao F
ACS biomaterials science & engineering 2024 Mar 11;10(3):1530-1543
ACS biomaterials science & engineering 2024 Mar 11;10(3):1530-1543
Atrazine exposure promotes cardiomyocyte pyroptosis to exacerbate cardiotoxicity by activating NF-κB pathway.
Zhao X, Luo H, Yao S, Yang T, Fu F, Yue M, Ruan H
The Science of the total environment 2024 Mar 10;915:170028
The Science of the total environment 2024 Mar 10;915:170028
Human amniotic MSCs-mediated anti-inflammation of CD206(hi)IL-10(hi) macrophages alleviates isoproterenol-induced ventricular remodeling in mice.
Huang QM, Long YL, Wang JN, Wu J, Tang WL, Wang XY, Zhang ZH, Zhuo YQ, Guan XH, Deng KY, Xin HB
International immunopharmacology 2024 Mar 10;129:111660
International immunopharmacology 2024 Mar 10;129:111660
Wuling capsule modulates macrophage polarization by inhibiting the TLR4-NF-κB signaling pathway to relieve liver fibrosis.
Ren S, Zhou R, Tang Z, Song Z, Li N, Shi X, Liu Y, Chu Y
International immunopharmacology 2024 Mar 10;129:111598
International immunopharmacology 2024 Mar 10;129:111598
SAP130 released by ferroptosis tubular epithelial cells promotes macrophage polarization via Mincle signaling in sepsis acute kidney injury.
Zhang J, Jiang J, Wang B, Wang Y, Qian Y, Suo J, Li Y, Peng Z
International immunopharmacology 2024 Mar 10;129:111564
International immunopharmacology 2024 Mar 10;129:111564
The Anti-Atherosclerotic Effects of Buyang Huanwu Decoction through M1 and M2 Macrophage Polarization in an ApoE Knockout Mouse Model.
Ji M, Mao L, Wei Y, Zhu B, Zhai Y, Zhou X, Tao W, Wang W, Wu H
Journal of physiological investigation 2024 Mar 1;67(2):79-87
Journal of physiological investigation 2024 Mar 1;67(2):79-87
Ponicidin-induced conformational changes of HSP90 regulates the MAPK pathway to relieve ulcerative colitis.
Zhang X, Xu Y, Fan M, Lv X, Long J, Yang R, Zhang R, Liu Z, Gu J, Wu P, Wang C
Journal of ethnopharmacology 2024 Mar 1;321:117483
Journal of ethnopharmacology 2024 Mar 1;321:117483
MST1 knockdown inhibits osteoarthritis progression through Parkin-mediated mitophagy and Nrf2/NF-κB signalling pathway.
Ye H, Cai T, Shen Y, Zhao L, Zhang H, Yang J, Li F, Chen J, Shui X
Journal of cellular and molecular medicine 2024 Jun;28(11):e18476
Journal of cellular and molecular medicine 2024 Jun;28(11):e18476
Dihydroquercetin alleviates dopamine neuron loss via regulating TREM2 activation.
Yang R, Li DD, Li XX, Yang XX, Gao HM, Zhang F
International journal of biological macromolecules 2024 Jun;269(Pt 2):132179
International journal of biological macromolecules 2024 Jun;269(Pt 2):132179
Dual-crosslinking gelatin-hyaluronic acid methacrylate based biomimetic PDAC desmoplastic niche enhances tumor-associated macrophages recruitment and M2-like polarization.
Wu D, Gong T, Sun Z, Yao X, Wang D, Chen Q, Guo Q, Li X, Guo Y, Lu Y
International journal of biological macromolecules 2024 Jun;269(Pt 1):131826
International journal of biological macromolecules 2024 Jun;269(Pt 1):131826
CircRNA CDR1as affects functional repair after spinal cord injury and regulates fibrosis through the SMAD pathway.
Wang W, Liu C, He D, Shi G, Song P, Zhang B, Li T, Wei J, Jiang Y, Ma L
Pharmacological research 2024 Jun;204:107189
Pharmacological research 2024 Jun;204:107189
POSTN knockdown suppresses IL-1β-induced inflammation and apoptosis of nucleus pulposus cells via inhibiting the NF-κB pathway and alleviates intervertebral disc degeneration.
Wang Z, Zhu D, Yang F, Chen H, Kang J, Liu W, Lin A, Kang X
Journal of cell communication and signaling 2024 Jun;18(2):e12030
Journal of cell communication and signaling 2024 Jun;18(2):e12030
The antidepressant effects of protein arginine methyltransferase 2 involve neuroinflammation.
Liu S, Zhang B, Guo H, Ding Z, Hou W, Hu X, Wang Y, Tan W, Zhou S
Neurochemistry international 2024 Jun;176:105728
Neurochemistry international 2024 Jun;176:105728
PPARG-mediated autophagy activation alleviates inflammation in rheumatoid arthritis.
Geng Q, Xu J, Cao X, Wang Z, Jiao Y, Diao W, Wang X, Wang Z, Zhang M, Zhao L, Yang L, Deng T, Fan B, Xu Y, Jia L, Xiao C
Journal of autoimmunity 2024 Jun;146:103214
Journal of autoimmunity 2024 Jun;146:103214
Exosomes from adipose-derived stem cells regulate macrophage polarization and accelerate diabetic wound healing via the circ-Rps5/miR-124-3p axis.
Yin D, Shen G
Immunity, inflammation and disease 2024 Jun;12(6):e1274
Immunity, inflammation and disease 2024 Jun;12(6):e1274
NIR triggered polydopamine coated cerium dioxide nanozyme for ameliorating acute lung injury via enhanced ROS scavenging.
Yin M, Lei D, Liu Y, Qin T, Gao H, Lv W, Liu Q, Qin L, Jin W, Chen Y, Liang H, Wang B, Gao M, Zhang J, Lu J
Journal of nanobiotechnology 2024 Jun 8;22(1):321
Journal of nanobiotechnology 2024 Jun 8;22(1):321
Chishao - Fuzi herbal pair restore the macrophage M1/M2 balance in acute-on-chronic liver failure.
Tan N, Jian G, Peng J, Tian X, Chen B
Journal of ethnopharmacology 2024 Jun 28;328:118010
Journal of ethnopharmacology 2024 Jun 28;328:118010
Programmed cell death factor 4-mediated hippocampal synaptic plasticity is involved in early life stress and susceptibility to depression.
Cheng J, Yuan L, Yu S, Gu B, Luo Q, Wang X, Zhao Y, Gai C, Li T, Liu W, Wang Z, Liu D, Ho RCM, Ho CSH
Behavioural brain research 2024 Jun 25;468:115028
Behavioural brain research 2024 Jun 25;468:115028
Macrophage biomimetic nanoparticle-targeted functional extracellular vesicle micro-RNAs revealed via multiomics analysis alleviate sepsis-induced acute lung injury.
Wang G, Ma X, Huang W, Wang S, Lou A, Wang J, Tu Y, Cui W, Zhou W, Zhang W, Li Y, Geng S, Meng Y, Li X
Journal of nanobiotechnology 2024 Jun 23;22(1):362
Journal of nanobiotechnology 2024 Jun 23;22(1):362
Potential Molecular Mechanism of Illicium simonsii Maxim Petroleum Ether Fraction in the Treatment of Hepatocellular Carcinoma.
Zou S, Wu Y, Wen M, Liu J, Chen M, Yuan J, Zhou B
Pharmaceuticals (Basel, Switzerland) 2024 Jun 19;17(6)
Pharmaceuticals (Basel, Switzerland) 2024 Jun 19;17(6)
Involvement of P2X7R-mediated microglia polarization and neuroinflammation in the response to electroacupuncture on post-stroke memory impairment.
Lin B, Wang M, Chen X, Chai L, Ni J, Huang J
Brain research bulletin 2024 Jun 15;212:110967
Brain research bulletin 2024 Jun 15;212:110967
Cathelicidin-BF regulates the AMPK/SIRT1/NF-κB pathway to ameliorate murine osteoarthritis: In vitro and in vivo studie.
Zhou H, Zou L, Ren H, Shen Z, Lin Y, Cai H, Zhang J
International immunopharmacology 2024 Jun 15;134:112201
International immunopharmacology 2024 Jun 15;134:112201
Role of plasmacytoid dendritic cells in vascular dysfunction in mice with renovascular hypertension.
Srinivas B, Alluri K, Rhaleb NE, Belmadani S, Matrougui K
Heliyon 2024 Jun 15;10(11):e31799
Heliyon 2024 Jun 15;10(11):e31799
Integrated network pharmacology and pharmacological investigations to explore the potential mechanism of Ding-Chuan-Tang against chronic obstructive pulmonary disease.
Xu LT, Wang T, Han QT, Xu ZP, Wen XS, Wang XN, Shen T
Journal of ethnopharmacology 2024 Jun 12;327:117983
Journal of ethnopharmacology 2024 Jun 12;327:117983
ATF4 Contributes to Abdominal Aortic Aneurysm Formation via Modulating M1 Macrophage Polarization and Inflammation.
Yu H, Jiao X, Lv Q, Li L, Du Y, Hu C, Du Z, Li F, Wang Y, Gao X, Han L, Sun X, Chen D, Qin Y
Aging and disease 2024 Jun 10;16(3):1691-1708
Aging and disease 2024 Jun 10;16(3):1691-1708
Sr-Incorporated Bioactive Glass Remodels the Immunological Microenvironment by Enhancing the Mitochondrial Function of Macrophage via the PI3K/AKT/mTOR Signaling Pathway.
Qiu H, Xiong H, Zheng J, Peng Y, Wang C, Hu Q, Zhao F, Chen K
ACS biomaterials science & engineering 2024 Jun 10;10(6):3923-3934
ACS biomaterials science & engineering 2024 Jun 10;10(6):3923-3934
Calcitriol attenuates lipopolysaccharide-induced neuroinflammation and depressive-like behaviors by suppressing the P2X7R/NLRP3/caspase-1 pathway.
Wang C, Cui C, Xie X, Chen B, Feng L, Jiang P
Psychopharmacology 2024 Jul;241(7):1329-1343
Psychopharmacology 2024 Jul;241(7):1329-1343
Inonotus obliquus (Chaga) against HFD/STZ-induced glucolipid metabolism disorders and abnormal renal functions by regulating NOS-cGMP-PDE5 signaling pathway.
Feng Y, Liu J, Gong L, Han Z, Zhang Y, Li R, Liao H
Chinese journal of natural medicines 2024 Jul;22(7):619-631
Chinese journal of natural medicines 2024 Jul;22(7):619-631
Huangqin decoction attenuates spared nerve injury (SNI)-induced neuropathic pain by modulating microglial M1/M2 polarization partially mediated by intestinal nicotinamide metabolism.
Gao L, Zhang AP, Fu L, Li QW, Qin XM, Zhao J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155594
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155594
The cGAS/STING signaling pathway is involved in sevoflurane induced neuronal necroptosis via regulating microglia M1 polarization.
Zhang Q, Li Y, Liu Y, Wang X, Yang Y, Shi L
Cellular signalling 2024 Jul;119:111195
Cellular signalling 2024 Jul;119:111195
Myeloid-derived growth factor ameliorates dextran sodium sulfate-induced colitis by regulating macrophage polarization.
Yang Y, Zhao C, Yang Z, Du C, Chang Z, Wen X, Zhang X, Liu Y, Hu L, Gao Z
Journal of molecular medicine (Berlin, Germany) 2024 Jul;102(7):875-886
Journal of molecular medicine (Berlin, Germany) 2024 Jul;102(7):875-886
Nonswellable Hydrogel Patch with Tissue-Mimetic Mechanical Characteristics Remodeling In Vivo Microenvironment for Effective Adhesion Prevention.
Liu X, Qiu X, Nie L, Zhou B, Bu P, Li Y, Xue X, Tang B, Feng Q, Cai K
ACS nano 2024 Jul 9;18(27):17651-17671
ACS nano 2024 Jul 9;18(27):17651-17671
Acetyl-11-keto-β-boswellic acid restrains the progression of synovitis in osteoarthritis via the Nrf2/HO-1 pathway.
Zhou J, Li X, Han Z, Qian Y, Bai L, Han Q, Gao M, Xue Y, Geng D, Yang X, Hao Y
Acta biochimica et biophysica Sinica 2024 Jul 8;56(11):1644-1658
Acta biochimica et biophysica Sinica 2024 Jul 8;56(11):1644-1658
Biomimetic NO Scavenging Hyaluronic Acid Nanoparticles Enable Targeted Delivery of MTX and Integrated Management of Rheumatoid Arthritis.
Liu Y, Luo H, Liu B, Zhou T, Zhang Z, Liu Z
Biomacromolecules 2024 Jul 8;25(7):4557-4568
Biomacromolecules 2024 Jul 8;25(7):4557-4568
Sestrin2 Restricts Endothelial-to-Mesenchymal Transition Induced by Lipolysaccharide via Autophagy.
Huang R, Liu L, Shen K, Duan C, Fan Z
Journal of integrative neuroscience 2024 Jul 5;23(7):124
Journal of integrative neuroscience 2024 Jul 5;23(7):124
A Comparative Study of the Stability, Transport, and Structure-Activity Relationship of Round Scad Derived Peptides with Antineuroinflammatory Ability.
Zhang Q, Wang Y, Zhao L, Su G, Ding W, Zheng L, Zhao M
Journal of agricultural and food chemistry 2024 Jul 31;72(30):17017-17029
Journal of agricultural and food chemistry 2024 Jul 31;72(30):17017-17029
Multifunctional Microneedle Patch Based on Metal-Phenolic Network with Photothermal Antimicrobial, ROS Scavenging, Immunomodulatory, and Angiogenesis for Programmed Treatment of Diabetic Wound Healing.
Guo Y, Zhang C, Xie B, Xu W, Rao Z, Zhou P, Ma X, Chen J, Cai R, Tao G, He Y
ACS applied materials & interfaces 2024 Jul 3;16(26):33205-33222
ACS applied materials & interfaces 2024 Jul 3;16(26):33205-33222
Pain Relief, Functional Recovery, and Chondroprotective Effects of Angelica gigas Nakai in Osteoarthritis Due to Its Anti-Inflammatory Property: An In Vitro and In Vivo Study.
Jo HG, Baek CY, Hwang Y, Baek E, Song HS, Lee D
Nutrients 2024 Jul 26;16(15)
Nutrients 2024 Jul 26;16(15)
Zhen-wu-tang protects against myocardial fibrosis by inhibiting M1 macrophage polarization via the TLR4/NF-κB pathway.
Fang R, Zhou R, Ju D, Li M, Wang H, Pan L, Wang X, Han M, Yu Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul 25;130:155719
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul 25;130:155719
Exploring the Mechanism of Asiatic Acid against Atherosclerosis Based on Molecular Docking, Molecular Dynamics, and Experimental Verification.
Wu Z, Yang L, Wang R, Yang J, Liang P, Ren W, Yu H
Pharmaceuticals (Basel, Switzerland) 2024 Jul 22;17(7)
Pharmaceuticals (Basel, Switzerland) 2024 Jul 22;17(7)
Adipose-derived stem cell exosomes loaded with icariin alleviates rheumatoid arthritis by modulating macrophage polarization in rats.
Yan Q, Liu H, Sun S, Yang Y, Fan D, Yang Y, Zhao Y, Song Z, Chen Y, Zhu R, Zhang Z
Journal of nanobiotechnology 2024 Jul 18;22(1):423
Journal of nanobiotechnology 2024 Jul 18;22(1):423
Effects and underlying mechanism of micro-nano-structured zirconia surfaces on biological behaviors of human gingival fibroblasts under inflammatory conditions.
Sun J, Ding Q, Chen Y, Li J, Wang Z, Wei Z, Ge X, Zhang L
Acta biomaterialia 2024 Jul 15;183:356-370
Acta biomaterialia 2024 Jul 15;183:356-370
Shape-fixing hydrogel promotes scarless healing of wounds under tension.
Fu D, Huang J, Wu X, Li Y, Zhang Y, Chen L, Liu Z, He Y, Zhou Y, Yang L, Hu Z, Miao Y
Acta biomaterialia 2024 Jul 15;183:173-190
Acta biomaterialia 2024 Jul 15;183:173-190
MSCs-exosomes can promote macrophage M2 polarization via exosomal miR-21-5p through Mesenteric injection: a promising way to attenuate murine colitis.
Qian W, Wu E, Chen H, Yao J, Wang J, Zhou Y, Bai Y, Wang S, Shen C, Li Y, Zhang Y
Journal of Crohn's & colitis 2024 Jul 13;
Journal of Crohn's & colitis 2024 Jul 13;
A Blend of Tamarindus Indica and Curcuma Longa Extracts Alleviates Monosodium Iodoacetate (MIA)-Induced Osteoarthritic Pain and Joint Inflammation in Rats.
Kwon SB, Chinta G, Kundimi S, Kim S, Cho YD, Kim SK, Ju JY, Sengupta K
Journal of the American Nutrition Association 2024 Jan;43(1):48-58
Journal of the American Nutrition Association 2024 Jan;43(1):48-58
Anti-inflammatory activities of several diterpenoids isolated from Hemionitis albofusca.
Pei X, Lou Y, Ren Q, Liu Y, Dai X, Ye M, Huang G, Cao J
Naunyn-Schmiedeberg's archives of pharmacology 2024 Jan;397(1):437-449
Naunyn-Schmiedeberg's archives of pharmacology 2024 Jan;397(1):437-449
STING modulates iron metabolism to promote liver injury and inflammation in acute immune hepatitis.
Zhao J, Yi Z, Deng G, Li Y, Li J, Qin M, Wu C, Luo P, Ma S, Gao L
Free radical biology & medicine 2024 Jan;210:367-377
Free radical biology & medicine 2024 Jan;210:367-377
NRF2 interacts with distal enhancer and inhibits nitric oxide synthase 2 expression in KRAS-driven pancreatic cancer cells.
Di Giorgio E, Cortolezzis Y, Gualandi N, Agostini F, Rapozzi V, Xodo LE
Biochimica et biophysica acta. Molecular cell research 2024 Jan;1871(1):119606
Biochimica et biophysica acta. Molecular cell research 2024 Jan;1871(1):119606
Ganoderic acid A slows osteoarthritis progression by attenuating endoplasmic reticulum stress and blocking NF-Κb pathway.
Liu Y, Zhou C, Tan J, Wu T, Pan C, Liu J, Cheng X
Chemical biology & drug design 2024 Jan;103(1):e14382
Chemical biology & drug design 2024 Jan;103(1):e14382
Mitochondria-derived peptide is an effective target for treating streptozotocin induced painful diabetic neuropathy through induction of activated protein kinase/peroxisome proliferator-activated receptor gamma coactivator 1alpha -mediated mitochondrial biogenesis.
Xu L, Tang X, Yang L, Chang M, Xu Y, Chen Q, Lu C, Liu S, Jiang J
Molecular pain 2024 Jan-Dec;20:17448069241252654
Molecular pain 2024 Jan-Dec;20:17448069241252654
Danggui-Shaoyao-San (DSS) ameliorates the progression of osteoarthritis via suppressing the NF-κB signaling pathway: an in vitro and in vivo study combined with bioinformatics analysis.
Chen S, Kang P, Zhao Z, Zhang H, Li J, Xu K, Gong D, Jiao F, Wang H, Zhang M
Aging 2024 Jan 8;16(1):648-664
Aging 2024 Jan 8;16(1):648-664
Liriodendrin exerts protective effects against chronic endometritis in rats by modulating gut microbiota composition and the arginine/nitric oxide metabolic pathway.
Cheng F, Li D, Ma X, Wang Y, Lu L, Hu B, Cui S
International immunopharmacology 2024 Jan 5;126:111235
International immunopharmacology 2024 Jan 5;126:111235
PCSK9 inhibitor protects against ischemic cerebral injury by attenuating inflammation via the GPNMB/CD44 pathway.
Zheng Y, Zhu T, Li G, Xu L, Zhang Y
International immunopharmacology 2024 Jan 5;126:111195
International immunopharmacology 2024 Jan 5;126:111195
Adipose-derived stem cell exosomes promote tumor characterization and immunosuppressive microenvironment in breast cancer.
Zhu Q, Cao Y, Yuan J, Hu Y
Cancer immunology, immunotherapy : CII 2024 Jan 31;73(2):39
Cancer immunology, immunotherapy : CII 2024 Jan 31;73(2):39
κ-Opioid receptor activation attenuates osteoarthritis synovitis by regulating macrophage polarization through the NF-κB pathway.
Shi Y, Tao H, Li X, Zhang L, Li C, Sun W, Chu M, Chen K, Zhu P, Wang Q, Gu C, Wang L, Yang X, Hao Y
Acta biochimica et biophysica Sinica 2024 Jan 25;56(1):82-95
Acta biochimica et biophysica Sinica 2024 Jan 25;56(1):82-95
Rosmarinic acid against cognitive impairment via RACK1/HIF-1α regulated microglial polarization in sepsis-surviving mice.
Liu DY, Wu Y, Feng ZQ, Yu Y, Cai HW, Liao SP, Zeng T, Zhu L, Wang X, Wan LH
Chemico-biological interactions 2024 Jan 25;388:110830
Chemico-biological interactions 2024 Jan 25;388:110830
Gypenoside XLIX attenuates sepsis-induced splenic injury through inhibiting inflammation and oxidative stress.
Xu B, Yang R, Qiang J, Xu X, Zhou M, Ji X, Lu Y, Dong Z
International immunopharmacology 2024 Jan 25;127:111420
International immunopharmacology 2024 Jan 25;127:111420
The protective effect of Ergolide in osteoarthritis: In vitro and in vivo studies.
Meng X, Sun L, Meng X, Bi Q
International immunopharmacology 2024 Jan 25;127:111355
International immunopharmacology 2024 Jan 25;127:111355
Liensinine alleviates mouse intestinal injury induced by sepsis through inhibition of oxidative stress, inflammation, and cell apoptosis.
Wang G, Ma F, Xie K, Li X, Tan X, Xia Y, Wang Y, Dong J
International immunopharmacology 2024 Jan 25;127:111335
International immunopharmacology 2024 Jan 25;127:111335
Rutin prevents pyroptosis and M1 microglia via Nrf2/Mac-1/caspase-1-mediated inflammasome axis to improve POCD.
Ji Y, Ma Y, Ma Y, Wang Y, Zhao X, Jin D, Xu L, Ge S
International immunopharmacology 2024 Jan 25;127:111290
International immunopharmacology 2024 Jan 25;127:111290
Comparison of the inhibition effects of naringenin and its glycosides on LPS-induced inflammation in RAW 264.7 macrophages.
Cho SC, Shaw SY
Molecular biology reports 2024 Jan 2;51(1):56
Molecular biology reports 2024 Jan 2;51(1):56
METTL14 contributes to acute lung injury by stabilizing NLRP3 expression in an IGF2BP2-dependent manner.
Cao F, Chen G, Xu Y, Wang X, Tang X, Zhang W, Song X, Yang X, Zeng W, Xie J
Cell death & disease 2024 Jan 13;15(1):43
Cell death & disease 2024 Jan 13;15(1):43
Modified Simiaowan prevents and treats gouty arthritis via the Nrf2/NLRP3 inflammasome signaling pathway.
Qin DE, Liang W, Yu Y, Whelan EC, Yuan X, Wang ZL, Wu XW, Cao ZR, Hua SY, Yin L, Shi L, Liang T
Journal of ethnopharmacology 2024 Jan 10;318(Pt A):116906
Journal of ethnopharmacology 2024 Jan 10;318(Pt A):116906
TREM2 regulates BV2 microglia activation and influences corticosterone-induced neuroinflammation in depressive disorders.
Shi J, Wang X, Kang C, Liu J, Ma C, Yang L, Hu J, Zhao N
Brain research 2024 Jan 1;1822:148664
Brain research 2024 Jan 1;1822:148664
Activation of LXRs alleviates neuropathic pain-induced cognitive dysfunction by modulation of microglia polarization and synaptic plasticity via PI3K/AKT pathway.
Han S, Yuan X, Zhao F, Manyande A, Gao F, Wang J, Zhang W, Tian X
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2024 Feb;73(2):157-174
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2024 Feb;73(2):157-174
Alisol A Exerts Neuroprotective Effects Against HFD-Induced Pathological Brain Aging via the SIRT3-NF-κB/MAPK Pathway.
Lu T, Ding L, Zheng X, Li Y, Wei W, Liu W, Tao J, Xue X
Molecular neurobiology 2024 Feb;61(2):753-771
Molecular neurobiology 2024 Feb;61(2):753-771
Caffeic acid alleviates cerebral ischemic injury in rats by resisting ferroptosis via Nrf2 signaling pathway.
Li XN, Shang NY, Kang YY, Sheng N, Lan JQ, Tang JS, Wu L, Zhang JL, Peng Y
Acta pharmacologica Sinica 2024 Feb;45(2):248-267
Acta pharmacologica Sinica 2024 Feb;45(2):248-267
METTL3 promotes microglial inflammation via MEF2C in spinal cord injury.
Wang D, Qian W, Wu D, Wu Y, Lu K, Zou G
Cell and tissue research 2024 Feb;395(2):189-197
Cell and tissue research 2024 Feb;395(2):189-197
Targeted transplantation of engineered mitochondrial compound promotes functional recovery after spinal cord injury by enhancing macrophage phagocytosis.
Xu J, Shi C, Yuan F, Ding Y, Xie Y, Liu Y, Zhu F, Lu H, Duan C, Hu J, Jiang L
Bioactive materials 2024 Feb;32:427-444
Bioactive materials 2024 Feb;32:427-444
Reprogramming macrophages via immune cell mobilized hydrogel microspheres for osteoarthritis treatments.
Xiao P, Han X, Huang Y, Yang J, Chen L, Cai Z, Hu N, Cui W, Huang W
Bioactive materials 2024 Feb;32:242-259
Bioactive materials 2024 Feb;32:242-259
A dihydromyricetin-loaded phellinus igniarius polysaccharide/l-arginine modified chitosan-based hydrogel for promoting wound recovery in diabetic mice via JNK and TGF-β/Smad signaling pathway.
Yang J, Zhang L, Sun S, Zhang S, Ding Q, Chai G, Yu W, Zhao T, Shen L, Gao Y, Liu W, Ding C
International journal of biological macromolecules 2024 Feb;259(Pt 1):129124
International journal of biological macromolecules 2024 Feb;259(Pt 1):129124
The mechanism of adipose mesenchymal stem cells to stabilize the immune microenvironment of pelvic floor injury by regulating pyroptosis and promoting tissue repair.
Wu X, Zhang F, Mao X, Xu F, Ding X, Sun X, Wang J
Materials today. Bio 2024 Feb;24:100910
Materials today. Bio 2024 Feb;24:100910
In vitro and in vivo biological evaluation of Lappaconitine derivatives as potential anti-inflammatory agents.
Xiao Y, Han M, Chen Y, Li YZ, Zhang YY, Chen L, Huang S, Zhou XL
Chemistry & biodiversity 2024 Feb;21(2):e202301761
Chemistry & biodiversity 2024 Feb;21(2):e202301761
Early life stress enhances the susceptibility to depression and interferes with neuroplasticity in the hippocampus of adolescent mice via regulating miR-34c-5p/SYT1 axis.
Yu S, Zhao Y, Luo Q, Gu B, Wang X, Cheng J, Wang Z, Liu D, Ho RCM, Ho CSH
Journal of psychiatric research 2024 Feb;170:262-276
Journal of psychiatric research 2024 Feb;170:262-276
Aerobic Glycolysis Induced by mTOR/HIF-1α Promotes Early Brain Injury After Subarachnoid Hemorrhage via Activating M1 Microglia.
Sun XG, Chu XH, Godje Godje IS, Liu SY, Hu HY, Zhang YB, Zhu LJ, Wang H, Sui C, Huang J, Shen YJ
Translational stroke research 2024 Feb;15(1):1-15
Translational stroke research 2024 Feb;15(1):1-15
Arteannuin B, a sesquiterpene lactone from Artemisia annua, attenuates inflammatory response by inhibiting the ubiquitin-conjugating enzyme UBE2D3-mediated NF-κB activation.
Chen H, Hu Q, Wen T, Luo L, Liu L, Wang L, Shen X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Feb;124:155263
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Feb;124:155263
PPM1G regulates hepatic ischemia/reperfusion injury through STING-mediated inflammatory pathways in macrophages.
Peng D, Huang Z, Yang H, Luo Y, Wu Z
Immunity, inflammation and disease 2024 Feb;12(2):e1189
Immunity, inflammation and disease 2024 Feb;12(2):e1189
A Novel Cargo Delivery System-AnCar-Exo(LaIMTS) Ameliorates Arthritis via Specifically Targeting Pro-Inflammatory Macrophages.
Li S, Wu YR, Peng XQ, Chen HG, Zhang TY, Chen H, Yang J, Xie YL, Qi HB, Xiang W, Huang B, Zhou SR, Hu Y, Tan QY, Du XL, Huang JL, Zhang RB, Li XH, Luo FT, Jin M, Su N, Luo XQ, Huang S, Yang P, Yan XJ, Lian JQ, Zhu Y, Xiong Y, Xiao GY, Liu YY, Shen C, Kuang L, Ni ZH, Chen L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Feb;11(7):e2306143
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Feb;11(7):e2306143
TNF-α Levels Are Increased in Patients with Subjective Cognitive Impairment and Are Negatively Correlated with β Amyloid-42.
Serafini S, Ferretti G, Monterosso P, Angiolillo A, Di Costanzo A, Matrone C
Antioxidants (Basel, Switzerland) 2024 Feb 8;13(2)
Antioxidants (Basel, Switzerland) 2024 Feb 8;13(2)
Fabrication of levofloxacin-loaded porcine acellular dermal matrix hydrogel and functional assessment in urinary tract infection.
Yang Y, Yang GW, Lu JJ, Chen HR, Guo YQ, Yang N, Zhu YZ, Liu XQ, Su TT, Liu YY, Yu L, Li YS, Hu LF, Li JB
Journal of nanobiotechnology 2024 Feb 7;22(1):52
Journal of nanobiotechnology 2024 Feb 7;22(1):52
Multipathway Regulation for Targeted Atherosclerosis Therapy Using Anti-miR-33-Loaded DNA Origami.
Ma Y, Wang Q, Du S, Luo J, Sun X, Jia B, Ge J, Dong J, Jiang S, Li Z
ACS nano 2024 Feb 6;
ACS nano 2024 Feb 6;
Cathepsin B-Responsive Programmed Brain Targeted Delivery System for Chemo-Immunotherapy Combination Therapy of Glioblastoma.
Jiang S, Li W, Yang J, Zhang T, Zhang Y, Xu L, Hu B, Li Z, Gao H, Huang Y, Ruan S
ACS nano 2024 Feb 27;18(8):6445-6462
ACS nano 2024 Feb 27;18(8):6445-6462
Elucidating the mechanisms of formononetin in modulating atherosclerotic plaque formation in ApoE-/- mice.
He Y, Cai Y, Wei D, Cao L, He Q, Zhang Y
BMC cardiovascular disorders 2024 Feb 22;24(1):121
BMC cardiovascular disorders 2024 Feb 22;24(1):121
The Pea Oligosaccharides Could Stimulate the In Vitro Proliferation of Beneficial Bacteria and Enhance Anti-Inflammatory Effects via the NF-κB Pathway.
Cheng Y, Zhao R, Qiao M, Ma Y, Li T, Li N, Shen Y, Huang X, Song L
Foods (Basel, Switzerland) 2024 Feb 19;13(4)
Foods (Basel, Switzerland) 2024 Feb 19;13(4)
YTHDF2 alleviates microglia activation via promoting circHIPK2 degradation.
Huang R, Sun M, Wang W, Yu X, Liu F
Journal of neuroimmunology 2024 Feb 15;387:578265
Journal of neuroimmunology 2024 Feb 15;387:578265
TRIM65 knockout inhibits the development of HCC by polarization tumor-associated macrophages towards M1 phenotype via JAK1/STAT1 signaling pathway.
Jiang M, Wang D, Su N, Lou W, Chen Y, Yang H, Chen C, Xi F, Chen Y, Deng L, Tang X
International immunopharmacology 2024 Feb 15;128:111494
International immunopharmacology 2024 Feb 15;128:111494
An Amino Acids and Dipeptide Injection Inhibits the TNF-α/HMGB1 Inflammatory Signaling Pathway to Reduce Pyroptosis and M1 Microglial Polarization in POCD Mice: the Gut to the Brain.
Ji Y, Ma Y, Ma Y, Wang Y, Zhao X, Xu L, Ge S
Molecular neurobiology 2024 Dec;61(12):10097-10114
Molecular neurobiology 2024 Dec;61(12):10097-10114
Microglial EPOR Contribute to Sevoflurane-induced Developmental Fine Motor Deficits Through Synaptic Pruning in Mice.
He D, Shi X, Liang L, Zhao Y, Ma S, Cao S, Liu B, Gao Z, Zhang X, Fan Z, Kuang F, Zhang H
Neuroscience bulletin 2024 Dec;40(12):1858-1874
Neuroscience bulletin 2024 Dec;40(12):1858-1874
Oxyresveratrol reduces lipopolysaccharide-induced inflammation and oxidative stress through inactivation of MAPK and NF-κB signaling in brain endothelial cells.
Zhou Y, Deng Q, Vong CT, Khan H, Cheang WS
Biochemistry and biophysics reports 2024 Dec;40:101823
Biochemistry and biophysics reports 2024 Dec;40:101823
Esculin Alleviates Osteoarthritis Progression Through the Sirt1/NF-κB Pathway.
Sun T, Bai B, Wu H, Xing H, Li J
Phytotherapy research : PTR 2024 Dec;38(12):5793-5805
Phytotherapy research : PTR 2024 Dec;38(12):5793-5805
An injectable self-lubricating supramolecular polymer hydrogel loaded with platelet lysate to boost osteoarthritis treatment.
Zhang P, Yang J, Wang Z, Wang H, An M, Yakufu M, Wang W, Liu Y, Liu W, Li C
Journal of controlled release : official journal of the Controlled Release Society 2024 Dec;376:20-36
Journal of controlled release : official journal of the Controlled Release Society 2024 Dec;376:20-36
Engineering of phosphatidylserine-targeting ROS-responsive polymeric prodrug for the repair of ischemia-reperfusion-induced acute kidney injury.
Wang JH, Mao HB, Hu JB, Cheng S, Su H
Journal of controlled release : official journal of the Controlled Release Society 2024 Dec;376:1100-1114
Journal of controlled release : official journal of the Controlled Release Society 2024 Dec;376:1100-1114
TBK1 is involved in M-CSF-induced macrophage polarization through mediating the IRF5/IRF4 axis.
Li Y, Ji L, Liu C, Li J, Wen D, Li Z, Yu L, Guo M, Zhang S, Duan W, Yi L, Bi Y, Bu H, Li C, Liu Y
The FEBS journal 2024 Dec;291(23):5214-5235
The FEBS journal 2024 Dec;291(23):5214-5235
An advanced chitosan based sponges dressing system with antioxidative, immunoregulation, angiogenesis and neurogenesis for promoting diabetic wound healing.
Fan X, Su Z, Zhang W, Huang H, He C, Wu Z, Zhang P
Materials today. Bio 2024 Dec;29:101361
Materials today. Bio 2024 Dec;29:101361
Injectable hyaluronate-based hydrogel with a dynamic/covalent dual-crosslinked architecture for bone tissue engineering: Enhancing osteogenesis and immune regulation.
Guo K, Li G, Yu Q, Yang Y, Liu H, Zhao Y, Huang Y, Zhang H, Li W
International journal of biological macromolecules 2024 Dec;282(Pt 5):137249
International journal of biological macromolecules 2024 Dec;282(Pt 5):137249
Multifunctional carboxymethyl chitosan/oxidized carboxymethyl cellulose hydrogel loaded with ginsenoside Rg1 and polydopamine nanoparticles for infected diabetic wound healing.
Li S, Ren X, Liu Y, Wang L, Zhou Y, Zhang Y, Yan Z, Lan X, Guo L
International journal of biological macromolecules 2024 Dec;282(Pt 1):136686
International journal of biological macromolecules 2024 Dec;282(Pt 1):136686
Indole-3-Carboxaldehyde Inhibits Inflammatory Response and Lipid Accumulation in Macrophages Through the miR-1271-5p/HDAC9 Pathway.
Luo W, Meng J, Yu XH, Zhang ZZ, Wang G, He J
Journal of cellular and molecular medicine 2024 Dec;28(24):e70263
Journal of cellular and molecular medicine 2024 Dec;28(24):e70263
S-Nitrosylation of NOTCH1 Regulates Mesenchymal Stem Cells Differentiation Into Hepatocyte-Like Cells by Inhibiting Notch Signalling Pathway.
Wang X, Xu Y, Wang Y, Tang X, Zhou X, Lu W, Chen W, Li L, Zhou L, Ye J
Journal of cellular and molecular medicine 2024 Dec;28(23):e70274
Journal of cellular and molecular medicine 2024 Dec;28(23):e70274
Spatial dimension cues derived from fibrous scaffolds trigger mechanical activation to potentiate the paracrine and regenerative functions of MSCs via the FAK-PI3K/AKT axis.
Xu S, Zhang M, Wang R, Zhang J, Wang C, Xie L, Zhao W
Acta biomaterialia 2024 Dec;190:273-292
Acta biomaterialia 2024 Dec;190:273-292
Baliosperoid A attenuates lipopolysaccharide-induced acute lung injury by targeting SHP2 to inhibit inflammation and oxidative stress.
Li Y, Zhao L, Liu Z, Chen Y, Li X, Zhu D, Liu L
Bioorganic chemistry 2024 Dec;153:107982
Bioorganic chemistry 2024 Dec;153:107982
Targeted inhibition of Gus-expressing Enterococcus faecalis to promote intestinal stem cell and epithelial renovation contributes to the relief of irinotecan chemotoxicity by dehydrodiisoeugenol.
Gao R, Yue B, Lv C, Geng X, Yu Z, Wang H, Zhang B, Ai F, Wang Z, Liu D, Wang Z, Chen K, Dou W
Acta pharmaceutica Sinica. B 2024 Dec;14(12):5286-5304
Acta pharmaceutica Sinica. B 2024 Dec;14(12):5286-5304
The active ingredient of Evodia rutaecarpa reduces inflammation in knee osteoarthritis rats through blocking calcium influx and NF-κB pathway.
Gao Y, Wang S, Gao Y, Yang L
Basic & clinical pharmacology & toxicology 2024 Dec;135(6):705-719
Basic & clinical pharmacology & toxicology 2024 Dec;135(6):705-719
Praelolide alleviates collagen-induced arthritis through increasing catalase activity and activating Nrf2 pathway.
Qi X, Meng J, Li C, Cheng W, Fan A, Huang J, Lin W
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156040
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156040
Ultra-Long-Term Anti-Inflammatory Polyphenol Capsule to Remodel the Microenvironment for Accelerating Osteoarthritis Healing by Single Dosage.
Wei S, Shou Z, Yang D, Sun L, Guo Y, Wang Y, Zan X, Li L, Zhang C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Dec;11(48):e2407425
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Dec;11(48):e2407425
Lycopodium japonicum Thunb. inhibits chondrocyte apoptosis, senescence and inflammation in osteoarthritis through STING/NF-κB signaling pathway.
Ma J, Zhang H, Wang Z, Xu C, Tan H, Sun Y, Zheng R, Jin Z, Li Y, Ge X, Wu Y, Zhou Y
Journal of ethnopharmacology 2024 Dec 5;335:118660
Journal of ethnopharmacology 2024 Dec 5;335:118660
Nuciferine ameliorates osteoarthritis: An in vitro and in vivo study.
Peng M, Shen G, Tu Q, Zhang W, Wang J
International immunopharmacology 2024 Dec 5;142(Pt B):113098
International immunopharmacology 2024 Dec 5;142(Pt B):113098
Kongensin A targeting PI3K attenuates inflammation-induced osteoarthritis by modulating macrophage polarization and alleviating inflammatory signaling.
Guo Y, Wang P, Hu B, Wang L, Zhang Y, Wang J
International immunopharmacology 2024 Dec 5;142(Pt A):112948
International immunopharmacology 2024 Dec 5;142(Pt A):112948
Long-term hypothermia amplified neuroprotection by antagonizing intracranial pressure rebound after severe traumatic brain injury in rats.
Sun X, Xu S, Wang J, Li X, Sun H, Zhao W
Neuroreport 2024 Dec 4;35(17):1107-1116
Neuroreport 2024 Dec 4;35(17):1107-1116
Evaluation of the Anti-Amyloid and Anti-Inflammatory Properties of a Novel Vanadium(IV)-Curcumin Complex in Lipopolysaccharides-Stimulated Primary Rat Neuron-Microglia Mixed Cultures.
Katsipis G, Lavrentiadou SN, Geromichalos GD, Tsantarliotou MP, Halevas E, Litsardakis G, Pantazaki AA
International journal of molecular sciences 2024 Dec 31;26(1)
International journal of molecular sciences 2024 Dec 31;26(1)
Engineered Magneto-Piezoelectric Nanoparticles-Enhanced Scaffolds Disrupt Biofilms and Activate Oxidative Phosphorylation in Icam1(+) Macrophages for Infectious Bone Defect Regeneration.
Wu H, Chen C, Li J, Yu D, Wu X, Huang H, Tang Z, Wu Q, Yan S, Wang N, Wang M, Wei F, Yu Y, Wang D, Shi M, Yue X, Cao P, Zheng Z, Li X, Guo B, Shi L, Guo Z
ACS nano 2024 Dec 31;18(52):35575-35594
ACS nano 2024 Dec 31;18(52):35575-35594
Ibuprofen modulates macrophage polarization by downregulating poly (ADP-ribose) polymerase 1.
Wang PH, Wang Y, Guo YY, Ma ZH, Wu C, Xing L
International immunopharmacology 2024 Dec 25;143(Pt 3):113502
International immunopharmacology 2024 Dec 25;143(Pt 3):113502
Tet2 modulates M2 macrophage polarization via mRNA 5-methylcytosine in allergic rhinitis.
Fan W, Liu P, Tan L, Lv H, Zhou H, Tao Z, Xu Y
International immunopharmacology 2024 Dec 25;143(Pt 3):113495
International immunopharmacology 2024 Dec 25;143(Pt 3):113495
Wedelolactone alleviates inflammation and cartilage degeneration by suppressing the NF-κB signaling pathway in osteoarthritis.
Sun W, Yue J, Cui Y, Feng J, He Q, Liang J, You W, Shi H, Sun W, Yi Q
International immunopharmacology 2024 Dec 25;143(Pt 1):113359
International immunopharmacology 2024 Dec 25;143(Pt 1):113359
Sulforaphane potentiates the efficacy of chemoradiotherapy in glioblastoma by selectively targeting thioredoxin reductase 1.
Ge Y, Ge Z, Tian F, Tai X, Chen D, Sun S, Shi Z, Yin J, Wei G, Li D, Wang L, Xu W, Tong M, Liu F, Zhao L, Qian X, Ge X
Cancer letters 2024 Dec 24;611:217429
Cancer letters 2024 Dec 24;611:217429
Soyasaponin Bb/Gelatin-Methacryloyl Hydrogel for Cartilage Inflammation Inhibition.
Jiang Y, Li T, Liu B, Tian Y, Wang Y, Li T, Zhang D
ACS omega 2024 Dec 17;9(50):49597-49608
ACS omega 2024 Dec 17;9(50):49597-49608
Novel Glycyrrhetin Ureas Possessing 2-Hydroxy-3-enone A Ring: Modification, Anti-inflammatory Activity, and Targeted STING for the Remedy of Acute Kidney Injury.
Wang H, Wu X, Li Z, Rong K, Gao S, Tang W, Zhang J
ACS omega 2024 Dec 10;9(49):48821-48834
ACS omega 2024 Dec 10;9(49):48821-48834
Inhibition of LSD1 via SP2509 attenuated the progression of rheumatoid arthritis.
Yu Z, Li P, Gao D, Hu Y, Xia F, Liu L, Liu J, Liu W, Zhang H
Immunologic research 2024 Aug;72(4):797-810
Immunologic research 2024 Aug;72(4):797-810
Auraptene Mitigates Colitis Induced by Dextran Sulfate Sodium in Mice by Regulating Specific Intestinal Flora and Repairing the Intestinal Barrier.
Chen T, Jin N, Zhang Q, Li Z, Wang Q, Fang X
Inflammation 2024 Aug;47(4):1127-1141
Inflammation 2024 Aug;47(4):1127-1141
Fucoidan improving spinal cord injury recovery: Modulating microenvironment and promoting remyelination.
Shu H, Zhang X, Pu Y, Zhang Y, Huang S, Ma J, Cao L, Zhou X
CNS neuroscience & therapeutics 2024 Aug;30(8):e14903
CNS neuroscience & therapeutics 2024 Aug;30(8):e14903
A gelatin methacryloyl (GelMA) treated with gallic acid and coated with specially designed nanoparticles derived from ginseng enhances the healing of wounds in diabetic rats.
Yu YL, Zheng JC, Duan P, Cheng YN, Zhang H, Zheng L, Yu ZR, Xu JM, Hu HX, Pan ZY
International journal of biological macromolecules 2024 Aug;274(Pt 1):133372
International journal of biological macromolecules 2024 Aug;274(Pt 1):133372
Anti-ulcerative colitis effect of rotating magnetic field on DSS-induced mice by modulating colonic inflammatory deterioration.
Yang H, Zhou C, Nie S, Xu S, Li M, Yu Q, Wei Y, Wang X
Molecular immunology 2024 Aug;172:23-37
Molecular immunology 2024 Aug;172:23-37
Zwitterion-Lubricated Hydrogel Microspheres Encapsulated with Metformin Ameliorate Age-Associated Osteoarthritis.
Hou J, Lin Y, Zhu C, Chen Y, Lin R, Lin H, Liu D, Guan D, Yu B, Wang J, Wu H, Cui Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(30):e2402477
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(30):e2402477
Schisandrin B alleviates testicular inflammation and Sertoli cell apoptosis via AR-JNK pathway.
Zhang BY, Yang R, Zhu WQ, Zhu CL, Chen LX, Zhao YS, Zhang Y, Wang YQ, Jiang DZ, Tang B, Zhang XM
Scientific reports 2024 Aug 8;14(1):18418
Scientific reports 2024 Aug 8;14(1):18418
Quercetin-loaded Human Umbilical cord Mesenchymal Stem Cell-derived sEVs for Spinal Cord Injury Recovery.
Yang C, Xu T, Lu Y, Liu J, Chen C, Wang H, Chen X
Neuroscience 2024 Aug 6;552:14-28
Neuroscience 2024 Aug 6;552:14-28
Pterostilbene improves neurological dysfunction and neuroinflammation after ischaemic stroke via HDAC3/Nrf1-mediated microglial activation.
Chen Y, He W, Qiu J, Luo Y, Jiang C, Zhao F, Wei H, Meng J, Long T, Zhang X, Yang L, Xu Q, Wang J, Zhang C
Cellular & molecular biology letters 2024 Aug 28;29(1):114
Cellular & molecular biology letters 2024 Aug 28;29(1):114
Investigation of the mechanism of baicalein in the treatment of periodontitis based on network pharmacology, molecular docking and experimental validation.
Liu Y, Cao F, Shi M, Deng Z, Guo K, Fan T, Meng Y, Bu M, Ma Z
BMC oral health 2024 Aug 23;24(1):987
BMC oral health 2024 Aug 23;24(1):987
IL-1β mediates Candida tropicalis-induced immunosuppressive function of MDSCs to foster colorectal cancer.
Zhang Z, Chen Y, Pan X, Li P, Ren Z, Wang X, Chen Y, Shen S, Wang T, Lin A
Cell communication and signaling : CCS 2024 Aug 21;22(1):408
Cell communication and signaling : CCS 2024 Aug 21;22(1):408
Adipose-derived stem cell exosomes loaded with icariin attenuated M1 polarization of macrophages via inhibiting the TLR4/Myd88/NF-κB signaling pathway.
Yan Q, Song C, Liu H, Li Y, Ma J, Zhao Y, Song Z, Chen Y, Zhu R, Zhang Z
International immunopharmacology 2024 Aug 20;137:112448
International immunopharmacology 2024 Aug 20;137:112448
Effect of Scaffold Geometrical Structure on Macrophage Polarization during Bone Regeneration Using Honeycomb Tricalcium Phosphate.
Takabatake K, Tsujigiwa H, Nakano K, Chang A, Piao T, Inada Y, Arashima T, Morimatsu A, Tanaka A, Kawai H, Nagatsuka H
Materials (Basel, Switzerland) 2024 Aug 19;17(16)
Materials (Basel, Switzerland) 2024 Aug 19;17(16)
Anti-atopic dermatitis effect of fraxinellone via inhibiting IL-31 in vivo and in vitro.
Yang N, Deng J, Xu H, Dai H, Jin H, Shao H, Liu Y
Heliyon 2024 Aug 15;10(15):e35391
Heliyon 2024 Aug 15;10(15):e35391
Arjunolic acid ameliorates lipopolysaccharide-induced depressive behavior by inhibiting neuroinflammation via microglial SIRT1/AMPK/Notch1 signaling pathway.
Yang Y, Lai Y, Tong X, Li Z, Cheng Y, Tian LW
Journal of ethnopharmacology 2024 Aug 10;330:118225
Journal of ethnopharmacology 2024 Aug 10;330:118225
Gut dysbiosis contributes to SCFAs reduction-associated adipose tissue macrophage polarization in gestational diabetes mellitus.
Li H, Liu S, Chen H, Zhou L, Chen B, Wang M, Zhang D, Han TL, Zhang H
Life sciences 2024 Aug 1;350:122744
Life sciences 2024 Aug 1;350:122744
SS-31 inhibits mtDNA-cGAS-STING signaling to improve POCD by activating mitophagy in aged mice.
Ji Y, Ma Y, Ma Y, Wang Y, Zhao X, Jin D, Xu L, Ge S
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2024 Apr;73(4):641-654
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2024 Apr;73(4):641-654
Toll-like receptor 3 signaling drives enteric glial cells against dextran sulfate sodium-induced colitis in mice.
Zeng J, Lu QQ, Du XL, Yuan L, Yang XJ
Journal of molecular histology 2024 Apr;55(2):201-210
Journal of molecular histology 2024 Apr;55(2):201-210
Single‐cell RNA sequencing reveals inflammatory retinal microglia in experimental autoimmune uveitis.
Liu J, Liao X, Li N, Xu Z, Yang W, Zhou H, Liu Y, Zhang Z, Wang G, Hou S
MedComm 2024 Apr;5(4):e534
MedComm 2024 Apr;5(4):e534
Asiaticoside ameliorates DSS-induced colitis in mice by inhibiting inflammatory response, protecting intestinal barrier and regulating intestinal microecology.
Liu K, Yin Y, Shi C, Yan C, Zhang Y, Qiu L, He S, Li G
Phytotherapy research : PTR 2024 Apr;38(4):2023-2040
Phytotherapy research : PTR 2024 Apr;38(4):2023-2040
Biomimetic nano-chelate diethyldithiocarbamate Cu/Fe for enhanced metalloimmunity and ferroptosis activation in glioma therapy.
Wang R, Song W, Zhu J, Shao X, Yang C, Xiong W, Wang B, Zhao P, Chen M, Huang Y
Journal of controlled release : official journal of the Controlled Release Society 2024 Apr;368:84-96
Journal of controlled release : official journal of the Controlled Release Society 2024 Apr;368:84-96
Liensinine reduces acute lung injury brought on by lipopolysaccharide by inhibiting the activation of the NF-κB signaling pathway through modification of the Src/TRAF6/TAK1 axis.
Chen H, Liu F, Dai D, Ming Y, Xu Y, Huang Z, Zhang L, Sun Y
Inflammopharmacology 2024 Apr;32(2):1475-1488
Inflammopharmacology 2024 Apr;32(2):1475-1488
Platycodon grandiflorus polysaccharide inhibits the inflammatory response of 3D4/21 cells infected with PCV2.
Guo X, Zhao X, Li L, Jiang M, Zhou A, Gao Y, Zheng P, Liu J, Zhao X
Microbial pathogenesis 2024 Apr;189:106592
Microbial pathogenesis 2024 Apr;189:106592
Spermidine ameliorates osteoarthritis via altering macrophage polarization.
Ou Q, Tang S, Zhu J, Xue S, Huang H, Zhao Y, Cai Y, Wu C, Chen J, Ruan G, Ding C
Biochimica et biophysica acta. Molecular basis of disease 2024 Apr;1870(4):167083
Biochimica et biophysica acta. Molecular basis of disease 2024 Apr;1870(4):167083
Cynaroside improved depressive-like behavior in CUMS mice by suppressing microglial inflammation and ferroptosis.
Zhou Y, Huang Y, Ye W, Chen Z, Yuan Z
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Apr;173:116425
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Apr;173:116425
Tumor necrosis factor α-induced protein 8-like-2 controls microglia phenotype via metabolic reprogramming in BV2 microglial cells and responses to neuropathic pain.
Li Y, Yin C, Jiang J, Yang H, Zhang F, Xing Y, Wang W, Lu C
The international journal of biochemistry & cell biology 2024 Apr;169:106541
The international journal of biochemistry & cell biology 2024 Apr;169:106541
5Z-7-Oxozaenol attenuates cuprizone-induced demyelination in mice through microglia polarization regulation.
Chen S, Liu S, Huang Y, Huang S, Zhang W, Xie H, Lu L
Brain and behavior 2024 Apr;14(4):e3487
Brain and behavior 2024 Apr;14(4):e3487
Baohuoside I suppresses the NLRP3 inflammasome activation via targeting GPER to fight against Parkinson's disease.
Gu Y, Hu ZF, Zheng DW, Yang YQ, Dong XL, Chen WF
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Apr;126:155435
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Apr;126:155435
Engineered Extracellular Vesicles Driven by Erythrocytes Ameliorate Bacterial Sepsis by Iron Recycling, Toxin Clearing and Inflammation Regulation.
Li Y, Qu G, Dou G, Ren L, Dang M, Kuang H, Bao L, Ding F, Xu G, Zhang Z, Yang C, Liu S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Apr;11(13):e2306884
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Apr;11(13):e2306884
Myricetin Oligomer Triggers Multi-Receptor Mediated Penetration and Autophagic Restoration of Blood-Brain Barrier for Ischemic Stroke Treatment.
Liu L, Ma Z, Han Q, Meng W, Wang H, Guan X, Shi Q
ACS nano 2024 Apr 9;18(14):9895-9916
ACS nano 2024 Apr 9;18(14):9895-9916
Baicalin reduces inflammation to inhibit lung cancer via targeting SOCS1/NF-κB/STAT3 axis.
Guo L, Yue M, Ma C, Wang Y, Hou J, Li H
Heliyon 2024 Apr 30;10(8):e29361
Heliyon 2024 Apr 30;10(8):e29361
Electroacupuncture promotes macrophage/microglial M2 polarization and suppresses inflammatory pain through AMPK.
Nan FB, Gu YX, Wang JL, Chen SD
Neuroreport 2024 Apr 3;35(6):343-351
Neuroreport 2024 Apr 3;35(6):343-351
Tannic Acid-Modified Decellularized Tendon Scaffold with Antioxidant and Anti-Inflammatory Activities for Tendon Regeneration.
Zhao LL, Luo JJ, Cui J, Li X, Hu RN, Xie XY, Zhang YJ, Ding W, Ning LJ, Luo JC, Qin TW
ACS applied materials & interfaces 2024 Apr 3;16(13):15879-15892
ACS applied materials & interfaces 2024 Apr 3;16(13):15879-15892
Network pharmacology and experimental validation of effects of total saponins extracted from Abrus cantoniensis Hance on acetaminophen-induced liver injury.
He J, Chen L, Wang P, Cen B, Li J, Wei Y, Yao X, Xu Z
Journal of ethnopharmacology 2024 Apr 24;324:117740
Journal of ethnopharmacology 2024 Apr 24;324:117740
Mas receptor activation facilitates innate hematoma resolution and neurological recovery after hemorrhagic stroke in mice.
Deng X, Ren J, Chen K, Zhang J, Zhang Q, Zeng J, Li T, Tang Q, Lin J, Zhu J
Journal of neuroinflammation 2024 Apr 24;21(1):106
Journal of neuroinflammation 2024 Apr 24;21(1):106
Chemotherapy-elicited extracellular vesicle CXCL1 from dying cells promotes triple-negative breast cancer metastasis by activating TAM/PD-L1 signaling.
Wang S, Li J, Hong S, Wang N, Xu S, Yang B, Zheng Y, Zhang J, Pan B, Hu Y, Wang Z
Journal of experimental & clinical cancer research : CR 2024 Apr 23;43(1):121
Journal of experimental & clinical cancer research : CR 2024 Apr 23;43(1):121
Physalin H ameliorates LPS-induced acute lung injury via KEAP1/NRF2 axis.
Cai Y, Zhu J, Zhu L, Hong L, Zhang J, Kong L, Chen C, Luo J
International immunopharmacology 2024 Apr 20;131:111789
International immunopharmacology 2024 Apr 20;131:111789
Chrysin Inhibits TAMs-Mediated Autophagy Activation via CDK1/ULK1 Pathway and Reverses TAMs-Mediated Growth-Promoting Effects in Non-Small Cell Lung Cancer.
Tang X, Luo X, Wang X, Zhang Y, Xie J, Niu X, Lu X, Deng X, Xu Z, Wu F
Pharmaceuticals (Basel, Switzerland) 2024 Apr 17;17(4)
Pharmaceuticals (Basel, Switzerland) 2024 Apr 17;17(4)
Baicalin Reduces Immune Cell Infiltration by Inhibiting Inflammation and Protecting Tight Junctions in Ischemic Stroke Injury.
Hao Z, Zhang Z, Zhao Y, Wang D
The American journal of Chinese medicine 2023;51(2):355-372
The American journal of Chinese medicine 2023;51(2):355-372
P-Glycoprotein Exacerbates Brain Injury Following Experimental Cerebral Ischemia by Promoting Proinflammatory Microglia Activation.
Chen Y, Fei X, Liu G, Li X, Huang L, Yang LZ, Li Y, Xu B, Fang W
Oxidative medicine and cellular longevity 2023;2023:6916819
Oxidative medicine and cellular longevity 2023;2023:6916819
Periventricular Microglia Polarization and Morphological Changes Accompany NLRP3 Inflammasome-Mediated Neuroinflammation after Hypoxic-Ischemic White Matter Damage in Premature Rats.
Yang L, Zhang Y, Yu X, Li D, Liu N, Xue X, Fu J
Journal of immunology research 2023;2023:5149306
Journal of immunology research 2023;2023:5149306
Identifying Macrophage-Related Genes in Ulcerative Colitis Using Weighted Coexpression Network Analysis and Machine Learning.
Hong S, Wang H, Chan S, Zhang J, Chen B, Ma X, Chen X
Mediators of inflammation 2023;2023:4373840
Mediators of inflammation 2023;2023:4373840
Ninjinyoeito Prevents Onset of Depression-Like Behavior and Reduces Hippocampal iNOS Expression in Senescence-Accelerated Mouse Prone 8 Mice.
Taniguchi C, Watanabe T, Hirata M, Hatae A, Kubota K, Katsurabayashi S, Iwasaki K
Evidence-based complementary and alternative medicine : eCAM 2023;2023:2151004
Evidence-based complementary and alternative medicine : eCAM 2023;2023:2151004
Donor Mesenchymal Stem Cells Program Bone Marrow, Altering Macrophages, and Suppressing Endometriosis in Mice.
Habata S, Mamillapalli R, Ucar A, Taylor HS
Stem cells international 2023;2023:1598127
Stem cells international 2023;2023:1598127
TREM-1 governs NLRP3 inflammasome activation of macrophages by firing up glycolysis in acute lung injury.
Zhong WJ, Liu T, Yang HH, Duan JX, Yang JT, Guan XX, Xiong JB, Zhang YF, Zhang CY, Zhou Y, Guan CX
International journal of biological sciences 2023;19(1):242-257
International journal of biological sciences 2023;19(1):242-257
Up-Regulation of miR-9-5p Inhibits Hypoxia-Ischemia Brain Damage Through the DDIT4-Mediated Autophagy Pathways in Neonatal Mice.
Gai C, Xing X, Song Y, Zhao Y, Jiang Z, Cheng Y, Xiao Y, Wang Z
Drug design, development and therapy 2023;17:1175-1189
Drug design, development and therapy 2023;17:1175-1189
Unveiling FOS as a Potential Diagnostic Biomarker and Emetine as a Prospective Therapeutic Agent for Diabetic Nephropathy.
Lin J, Li X, Lin Y, Huang Z, He F, Xiong F
Journal of inflammation research 2023;16:6139-6153
Journal of inflammation research 2023;16:6139-6153
Integrated Analysis of Non-Coding RNA and mRNA Expression Profiles in Exosomes from Lung Tissue with Sepsis-Induced Acute Lung Injury.
Deng W, Lu Y, Hu P, Zhang Q, Li S, Yang D, Zhao N, Qian K, Liu F
Journal of inflammation research 2023;16:3879-3895
Journal of inflammation research 2023;16:3879-3895
Activation of the microglial P2X7R/NLRP3 inflammasome mediates central sensitization in a mouse model of medication overuse headache.
Wang Y, Dong L, Zhang Y, Zhang Y, Qin G, Zhang D, Chen L, He W, Zhou J
Frontiers in molecular neuroscience 2023;16:1177171
Frontiers in molecular neuroscience 2023;16:1177171
FGL2 deficiency alleviates maternal inflammation-induced blood-brain barrier damage by blocking PI3K/NF-κB mediated endothelial oxidative stress.
Huang L, Zhan D, Xing Y, Yan Y, Li Q, Zhang J, Li S, Ning Q, Zhang C, Luo X
Frontiers in immunology 2023;14:1157027
Frontiers in immunology 2023;14:1157027
PLEKHA4 is a novel prognostic biomarker that reshapes the tumor microenvironment in lower-grade glioma.
Zhi W, Wang Y, Jiang C, Gong Y, Chen Q, Mao X, Deng W, Zhao S
Frontiers in immunology 2023;14:1128244
Frontiers in immunology 2023;14:1128244
Norbergenin prevents LPS-induced inflammatory responses in macrophages through inhibiting NFκB, MAPK and STAT3 activation and blocking metabolic reprogramming.
Li W, Cai Z, Schindler F, Bahiraii S, Brenner M, Heiss EH, Weckwerth W
Frontiers in immunology 2023;14:1117638
Frontiers in immunology 2023;14:1117638
Lycium barbarum polysaccharide alleviates dextran sodium sulfate-induced inflammatory bowel disease by regulating M1/M2 macrophage polarization via the STAT1 and STAT6 pathways.
Wang J, Gao H, Xie Y, Wang P, Li Y, Zhao J, Wang C, Ma X, Wang Y, Mao Q, Xia H
Frontiers in pharmacology 2023;14:1044576
Frontiers in pharmacology 2023;14:1044576
Sialidase facilitates Porphyromonas gingivalis immune evasion by reducing M1 polarization, antigen presentation, and phagocytosis of infected macrophages.
Fan X, Zheng S, Chen C, Lin L, Wang H, Shen Y, Pan Y, Li C
Frontiers in cellular and infection microbiology 2023;13:1173899
Frontiers in cellular and infection microbiology 2023;13:1173899
Thermos-responsive hydrogel system encapsulated engineered exosomes attenuate inflammation and oxidative damage in acute spinal cord injury.
Xiao Y, Hu X, Jiang P, Qi Z
Frontiers in bioengineering and biotechnology 2023;11:1216878
Frontiers in bioengineering and biotechnology 2023;11:1216878
Tertiary Lymphoid Structures Are Related to Inflammatory Progression and Bone Loss in Human Apical Periodontitis.
Liu J, Yue J, Wang K, Zhou L, Mao H, Chen Z, Li Q, Zhang L
Journal of endodontics 2023 Sep;49(9):1138-1144
Journal of endodontics 2023 Sep;49(9):1138-1144
Aβ Induces Neuroinflammation and Microglial M1 Polarization via cGAS-STING-IFITM3 Signaling Pathway in BV-2 Cells.
Wu Z, Tang W, Ibrahim FEEM, Chen X, Yan H, Tao C, Wang Z, Guo Y, Fu Y, Wang Q, Ge Y
Neurochemical research 2023 Sep;48(9):2881-2894
Neurochemical research 2023 Sep;48(9):2881-2894
Gut microbiota-derived short-chain fatty acids promote prostate cancer progression via inducing cancer cell autophagy and M2 macrophage polarization.
Liu Y, Zhou Q, Ye F, Yang C, Jiang H
Neoplasia (New York, N.Y.) 2023 Sep;43:100928
Neoplasia (New York, N.Y.) 2023 Sep;43:100928
Salidroside ameliorated the pulmonary inflammation induced by cigarette smoke via mitigating M1 macrophage polarization by JNK/c-Jun.
Feng H, Zhang D, Yin Y, Kang J, Zheng R
Phytotherapy research : PTR 2023 Sep;37(9):4251-4264
Phytotherapy research : PTR 2023 Sep;37(9):4251-4264
Notopterol alleviates the progression of osteoarthritis: An in vitro and in vivo study.
Qu Y, Qiu L, Qiu H, Shen Y, Tang M, Huang Y, Peng Y, Wang J, Fu Q
Cytokine 2023 Sep;169:156309
Cytokine 2023 Sep;169:156309
Caffeoylquinic acids isolated from Lonicera japonica Thunb. as TAK1 inhibitors protects against LPS plus IFN-γ-stimulated inflammation by interacting with KEAP1-regulated NRF2 activation.
Ge L, Jiang Y, Li Y, Xie Q, Miao Y, Wu Z, Zeng X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115038
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115038
Maslinic acid alleviates LPS-induced mice mastitis by inhibiting inflammatory response, maintaining the integrity of the blood-milk barrier and regulating intestinal flora.
Li K, Ran X, Zeng Y, Li S, Hu G, Wang X, Li Y, Yang Z, Liu J, Fu S
International immunopharmacology 2023 Sep;122:110551
International immunopharmacology 2023 Sep;122:110551
NDUFC2 deficiency exacerbates endothelial mesenchymal transformation during ischemia-reperfusion via NLRP3.
Chen J, Liu X, Bi R, Liu P, Gong W
Neuroreport 2023 Sep 6;34(13):670-676
Neuroreport 2023 Sep 6;34(13):670-676
A multifunctional polydopamine/genipin/alendronate nanoparticle licences fibrin hydrogels osteoinductive and immunomodulatory potencies for repairing bone defects.
Shi W, Gao Y, Wu Y, Sun J, Xu B, Lu X, Wang Q
International journal of biological macromolecules 2023 Sep 30;249:126072
International journal of biological macromolecules 2023 Sep 30;249:126072
Resveratrol alleviates DSS-induced IBD in mice by regulating the intestinal microbiota-macrophage-arginine metabolism axis.
Xu X, Ocansey DKW, Pei B, Zhang Y, Wang N, Wang Z, Mao F
European journal of medical research 2023 Sep 2;28(1):319
European journal of medical research 2023 Sep 2;28(1):319
Targeting STING-mediated pro-inflammatory and pro-fibrotic effects of alveolar macrophages and fibroblasts blunts silicosis caused by silica particles.
Ou L, Zhang P, Huang Z, Cheng Y, Miao Q, Niu R, Hu Y, Chen Y
Journal of hazardous materials 2023 Sep 15;458:131907
Journal of hazardous materials 2023 Sep 15;458:131907
Activation of GABA receptor attenuates intestinal inflammation by modulating enteric glial cells function through inhibiting NF-κB pathway.
Deng Z, Li D, Yan X, Lan J, Han D, Fan K, Chang J, Ma Y
Life sciences 2023 Sep 15;329:121984
Life sciences 2023 Sep 15;329:121984
FKN secreted by kidney epithelial cells regulates macrophage activation in lupus nephritis via the Hippo signaling pathway.
Zuo Y, Pan X, Wang X, You Y
Lupus 2023 Oct;32(12):1381-1393
Lupus 2023 Oct;32(12):1381-1393
Stem cell-derived hepatocyte therapy using versatile biomimetic nanozyme incorporated nanofiber-reinforced decellularized extracellular matrix hydrogels for the treatment of acute liver failure.
Jin Y, Zhang J, Xu Y, Yi K, Li F, Zhou H, Wang H, Chan HF, Lao YH, Lv S, Tao Y, Li M
Bioactive materials 2023 Oct;28:112-131
Bioactive materials 2023 Oct;28:112-131
Cocktail of three isoquinoline alkaloids derived from Glaucium grandiflorum Boiss. & A. Huet subsp. refractum (Nábelek) Mory inhibits the production of LPS-induced ROS, pro-inflammatory cytokines, and mediators through the down-regulation of p38 MAPK in BV-2 cells.
Nigdelioglu Dolanbay S, Şirin S, Aslim B
Fitoterapia 2023 Oct;170:105652
Fitoterapia 2023 Oct;170:105652
Geniposide ameliorates atherosclerosis by regulating macrophage polarization via perivascular adipocyte-derived CXCL14.
He P, Wang H, Cheng S, Hu F, Zhang L, Chen W, Xu Y, Zhang Y, Gu Y, Li Z, Jin Y, Liu X, Jia Y
Journal of ethnopharmacology 2023 Oct 5;314:116532
Journal of ethnopharmacology 2023 Oct 5;314:116532
Lactobacillus casei combined with Lactobacillus reuteri alleviate pancreatic cancer by inhibiting TLR4 to promote macrophage M1 polarization and regulate gut microbial homeostasis.
Zhu Z, Yi B, Tang Z, Chen X, Li M, Xu T, Zhao Z, Tang C
BMC cancer 2023 Oct 30;23(1):1044
BMC cancer 2023 Oct 30;23(1):1044
Bioinspired nanovesicles released from injectable hydrogels facilitate diabetic wound healing by regulating macrophage polarization and endothelial cell dysfunction.
Zhang W, Yang X, Huang X, Chen L
Journal of nanobiotechnology 2023 Oct 3;21(1):358
Journal of nanobiotechnology 2023 Oct 3;21(1):358
Melatonin Protects Bovine Spermatozoa by Reinforcing Their Antioxidant Defenses.
Lavrentiadou SN, Sapanidou V, Tzekaki EE, Margaritis I, Tsantarliotou MP
Animals : an open access journal from MDPI 2023 Oct 15;13(20)
Animals : an open access journal from MDPI 2023 Oct 15;13(20)
Combined Lycium barbarum Polysaccharides with Plasmon-Activated Water Affect IFN-γ/TNF-α Induced Inflammation in Caco-2 Cells.
Lian YZ, Liu YC, Chang CC, Nochi T, Chao JC
Pharmaceuticals (Basel, Switzerland) 2023 Oct 13;16(10)
Pharmaceuticals (Basel, Switzerland) 2023 Oct 13;16(10)
Attenuation of Chronic Stress-Induced Depressive-like Symptoms by Fish Oil via Alleviating Neuroinflammation and Impaired Tryptophan Metabolism in Aging Rats.
Tung TH, Lai WD, Lee HC, Su KP, Panunggal B, Huang SY
Journal of agricultural and food chemistry 2023 Oct 11;71(40):14550-14561
Journal of agricultural and food chemistry 2023 Oct 11;71(40):14550-14561
Oral administration of sophoricoside (SOP) inhibits neuronal damage and neuroinflammation to curb neurodegeneration in Parkinson's disease.
Wang H, He D, Li Z, Gao X, Yang S, Cui M, Ye B, Huang B, Fu S, Liu D
Chemico-biological interactions 2023 Oct 1;384:110726
Chemico-biological interactions 2023 Oct 1;384:110726
Umbilical cord mesenchymal stem cell-conditioned medium inhibits microglial activation to ameliorate neuroinflammation in amyotrophic lateral sclerosis mice and cell models.
Tang J, Kang Y, Zhou Y, Chen Q, Lan J, Liu X, Peng Y
Brain research bulletin 2023 Oct 1;202:110760
Brain research bulletin 2023 Oct 1;202:110760
Xanthohumol alleviates palmitate-induced inflammation and prevents osteoarthritis progression by attenuating mitochondria dysfunction/NLRP3 inflammasome axis.
Sun W, Yue J, Xu T, Cui Y, Huang D, Shi H, Xiong J, Sun W, Yi Q
Heliyon 2023 Nov;9(11):e21282
Heliyon 2023 Nov;9(11):e21282
GCH1 reduces LPS-induced alveolar macrophage polarization and inflammation by inhibition of ferroptosis.
Xiao Y, Yuan Y, Yang Y, Liu B, Ding Z, Luo J, Chen S, Yu L
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2023 Nov;72(10-11):1941-1955
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2023 Nov;72(10-11):1941-1955
Orientin inhibits inflammation in chondrocytes and attenuates osteoarthritis through Nrf2/NF-κB and SIRT6/NF-κB pathway.
Xia W, Xiao J, Tong C, Lu J, Tu Y, Li S, Ni L, Shi Y, Luo P, Zhang X, Wang X
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2023 Nov;41(11):2405-2417
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2023 Nov;41(11):2405-2417
Localized delivery of anti-inflammatory agents using extracellular matrix-nanostructured lipid carriers hydrogel promotes cardiac repair post-myocardial infarction.
Wang X, Shi H, Huang S, Zhang Y, He X, Long Q, Qian B, Zhong Y, Qi Z, Zhao Q, Ye X
Biomaterials 2023 Nov;302:122364
Biomaterials 2023 Nov;302:122364
Acetyl zingerone ameliorates osteoarthritis by inhibiting chondrocyte programmed cell death.
Chen X, Chen J, Miao C, Yin G, Zhang Z, Sun R, Ni S
Molecular medicine reports 2023 Nov;28(5)
Molecular medicine reports 2023 Nov;28(5)
Dauricine regulates prostate cancer progression by inhibiting PI3K/AKT-dependent M2 polarization of macrophages.
Li M, Che N, Liu X, Xuan Y, Jin Y
Biochemical pharmacology 2023 Nov;217:115838
Biochemical pharmacology 2023 Nov;217:115838
Berberine ameliorates collagen-induced arthritis in mice by restoring macrophage polarization via AMPK/mTORC1 pathway switching glycolytic reprogramming.
Cheng JW, Yu Y, Zong SY, Cai WW, Wang Y, Song YN, Xian H, Wei F
International immunopharmacology 2023 Nov;124(Pt B):111024
International immunopharmacology 2023 Nov;124(Pt B):111024
The metabolite butyrate produced by gut microbiota inhibits cachexia-associated skeletal muscle atrophy by regulating intestinal barrier function and macrophage polarization.
Liu H, Xi Q, Tan S, Qu Y, Meng Q, Zhang Y, Cheng Y, Wu G
International immunopharmacology 2023 Nov;124(Pt B):111001
International immunopharmacology 2023 Nov;124(Pt B):111001
Peroxisome proliferator-activated receptor gamma agonist pioglitazone alleviates hemorrhage-induced thalamic pain and neuroinflammation.
Li D, He L, Yuan C, Ai Y, Yang JJ
International immunopharmacology 2023 Nov;124(Pt B):110991
International immunopharmacology 2023 Nov;124(Pt B):110991
A natural sesquiterpene lactone isolinderalactone attenuates lipopolysaccharide-induced inflammatory response and acute lung injury through inhibition of NF-κB pathway and activation Nrf2 pathway in macrophages.
Shen X, Chen H, Zhang H, Luo L, Wen T, Liu L, Hu Q, Wang L
International immunopharmacology 2023 Nov;124(Pt B):110965
International immunopharmacology 2023 Nov;124(Pt B):110965
Pachymic acid suppresses the inflammatory response of chondrocytes and alleviates the progression of osteoarthritis via regulating the Sirtuin 6/NF-κB signal axis.
Wu Y, Ying J, Zhu X, Xu C, Wu L
International immunopharmacology 2023 Nov;124(Pt A):110854
International immunopharmacology 2023 Nov;124(Pt A):110854
CTRP6 regulates M1 macrophage polarization via the PPAR-γ/NF-κB pathway and reprogramming glycolysis in recurrent spontaneous abortion.
Yan S, Ding J, Wang Z, Zhang F, Li J, Zhang Y, Wu S, Yang L, Pang X, Zhang Y, Yang J
International immunopharmacology 2023 Nov;124(Pt A):110840
International immunopharmacology 2023 Nov;124(Pt A):110840
Rabdosichuanin C inhibits productions of pro-inflammatory mediators regulated by NF-κB signaling in LPS-stimulated RAW264.7 cells.
Lingxia Z, Hong W, Man G, Xinzhou W, Lili W, Zhimin W, Liping D, Erping X
Journal of cellular biochemistry 2023 Nov;124(11):1667-1684
Journal of cellular biochemistry 2023 Nov;124(11):1667-1684
Discovery of anti-neuroinflammatory agents from 1,4,5,6-tetrahydrobenzo[2,3]oxepino[4,5-d]pyrimidin-2-amine derivatives by regulating microglia polarization.
Yang Y, Gao ZF, Hou GG, Meng QG, Hou Y
European journal of medicinal chemistry 2023 Nov 5;259:115688
European journal of medicinal chemistry 2023 Nov 5;259:115688
Dapagliflozin protects against doxorubicin-induced nephrotoxicity associated with nitric oxide pathway-A translational study.
Chang WT, Wu CC, Liao IC, Lin YW, Chen YC, Ho CH, Lee WC, Lin YC, Chen ZC, Shih JY, Wu NC, Kan WC
Free radical biology & medicine 2023 Nov 1;208:103-111
Free radical biology & medicine 2023 Nov 1;208:103-111
Electroacupuncture Alleviates CFA-Induced Inflammatory Pain via PD-L1/PD-1-SHP-1 Pathway.
Deng D, Xu F, Ma L, Zhang T, Wang Y, Huang S, Zhao W, Chen X
Molecular neurobiology 2023 May;60(5):2922-2936
Molecular neurobiology 2023 May;60(5):2922-2936
Cannabinoid type 2 receptor activation inhibits MPP(+)-induced M1 differentiation of microglia through activating PI3K/Akt/Nrf2 signal pathway.
Wang M, Liu M, Ma Z
Molecular biology reports 2023 May;50(5):4423-4433
Molecular biology reports 2023 May;50(5):4423-4433
TAK1 deficiency promotes liver injury and tumorigenesis via ferroptosis and macrophage cGAS-STING signalling.
Su W, Gao W, Zhang R, Wang Q, Li L, Bu Q, Xu Z, Liu Z, Wang M, Zhu Y, Wu G, Zhou H, Wang X, Lu L
JHEP reports : innovation in hepatology 2023 May;5(5):100695
JHEP reports : innovation in hepatology 2023 May;5(5):100695
Activation of glucagon-like peptide-1 receptor in microglia exerts protective effects against sepsis-induced encephalopathy via attenuating endoplasmic reticulum stress-associated inflammation and apoptosis in a mouse model of sepsis.
Yi H, Duan Y, Song R, Zhou Y, Cui Y, Liu C, Mao Z, Hu J, Zhou F
Experimental neurology 2023 May;363:114348
Experimental neurology 2023 May;363:114348
miR-26a-5p alleviates CFA-induced chronic inflammatory hyperalgesia through Wnt5a/CaMKII/NFAT signaling in mice.
Lu Y, Liu M, Guo X, Wang P, Zeng F, Wang H, Tang J, Qin Z, Tao T
CNS neuroscience & therapeutics 2023 May;29(5):1254-1271
CNS neuroscience & therapeutics 2023 May;29(5):1254-1271
Macrophage membrane-coated nanovesicles for dual-targeted drug delivery to inhibit tumor and induce macrophage polarization.
Huang X, Wang L, Guo H, Zhang W
Bioactive materials 2023 May;23:69-79
Bioactive materials 2023 May;23:69-79
Delivery of coenzyme Q10 loaded micelle targets mitochondrial ROS and enhances efficiency of mesenchymal stem cell therapy in intervertebral disc degeneration.
Sun J, Yang F, Wang L, Yu H, Yang Z, Wei J, Vasilev K, Zhang X, Liu X, Zhao Y
Bioactive materials 2023 May;23:247-260
Bioactive materials 2023 May;23:247-260
TP53 mutation-related senescence is an indicator of hepatocellular carcinoma patient outcomes from multiomics profiles.
Chen YY, Zhu ZY, Ma T, Zhang L, Chen J, Jiang JW, Lu CH, Ding YT, Guan WX, Yi N, Ren HZ
Smart medicine 2023 May;2(2):e20230005
Smart medicine 2023 May;2(2):e20230005
A low-salt diet with candesartan administration is associated with acute kidney injury in nephritis by increasing nitric oxide.
Yu Y, Wang P, Ren Z, Xue Y, Jia Y, Wang W, Liu M, Pan K, Xiao L, Ji D, Wang X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 May;161:114484
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 May;161:114484
Baicalein ameliorates Alzheimer's disease via orchestration of CX3CR1/NF-κB pathway in a triple transgenic mouse model.
Xie XM, Hao JJ, Shi JZ, Zhou YF, Liu PF, Wang F, Zheng XM, Yu XY, Wang CC, Yan Y, Du GH, Song JK, He YY, Pang XB
International immunopharmacology 2023 May;118:109994
International immunopharmacology 2023 May;118:109994
Echinacea Polyphenols Inhibit NLRP3-Dependent Pyroptosis, Apoptosis, and Necroptosis via Suppressing NO Production during Lipopolysaccharide-Induced Acute Lung Injury.
Guo J, Luo Y, Zuo J, Teng J, Shen B, Liu X
Journal of agricultural and food chemistry 2023 May 17;71(19):7289-7298
Journal of agricultural and food chemistry 2023 May 17;71(19):7289-7298
Apigenin Alleviates Autoimmune Uveitis by Inhibiting Microglia M1 Pro-Inflammatory Polarization.
Shu N, Zhang Z, Wang X, Li R, Li W, Liu X, Zhang Q, Jiang Z, Tao L, Zhang L, Hou S
Investigative ophthalmology & visual science 2023 May 1;64(5):21
Investigative ophthalmology & visual science 2023 May 1;64(5):21
Cigarette smoke induces the ROS accumulation and iNOS activation through deactivation of Nrf-2/SIRT3 axis to mediate the human bronchial epithelium ferroptosis.
Zi Y, Wang X, Zi Y, Yu H, Lan Y, Fan Y, Ren C, Liao K, Chen H
Free radical biology & medicine 2023 May 1;200:73-86
Free radical biology & medicine 2023 May 1;200:73-86
Multiple low-dose radiation-induced neuronal cysteine transporter expression and oxidative stress are rescued by N-acetylcysteine in neuronal SH-SY5Y cells.
Yoo JY, Lee YJ, Kim YJ, Baik TK, Lee JH, Lee MJ, Woo RS
Neurotoxicology 2023 Mar;95:205-217
Neurotoxicology 2023 Mar;95:205-217
Lnc-17Rik promotes the immunosuppressive function of Myeloid-Derived suppressive cells in esophageal cancer.
Wen J, Xuan B, Gao Y, Liu Y, Wang L, He L, Meng X, Zhou T, Tao Y, Guo K, Wang Y
Cellular immunology 2023 Mar;385:104676
Cellular immunology 2023 Mar;385:104676
miR-449a ameliorates acute rejection after liver transplantation via targeting procollagen-lysine1,2-oxoglutarate5-dioxygenase 1 in macrophages.
Cao ZR, Zheng WX, Jiang YX, Chai H, Gong JH, Zhao MJ, Yan P, Liu YY, Liu XY, Huang ZT, Yang H, Peng DD, Zong KZ, Wu ZJ
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2023 Mar;23(3):336-352
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2023 Mar;23(3):336-352
TMEM16F may be a new therapeutic target for Alzheimer's disease.
Cui ZQ, Hu XY, Yang T, Guan JW, Gu Y, Li HY, Zhang HY, Xiao QH, Sun XH
Neural regeneration research 2023 Mar;18(3):643-651
Neural regeneration research 2023 Mar;18(3):643-651
The antimicrobial peptide LK2(6)A(L) exhibits anti-inflammatory activity by binding to the myeloid differentiation 2 domain and protects against LPS-induced acute lung injury in mice.
Zhang J, Sun Y, Sun C, Shang D
Bioorganic chemistry 2023 Mar;132:106376
Bioorganic chemistry 2023 Mar;132:106376
Onychiol B attenuates lipopolysaccharide-induced inflammation via MAPK/NF-κB pathways and acute lung injury in vivo.
Pei X, Zhang Z, Wang N, Huang G, Min X, Yang Y, Cao J
Bioorganic chemistry 2023 Mar;132:106351
Bioorganic chemistry 2023 Mar;132:106351
Garlic-derived exosomes carrying miR-396e shapes macrophage metabolic reprograming to mitigate the inflammatory response in obese adipose tissue.
Bian Y, Li W, Jiang X, Yin F, Yin L, Zhang Y, Guo H, Liu J
The Journal of nutritional biochemistry 2023 Mar;113:109249
The Journal of nutritional biochemistry 2023 Mar;113:109249
Activation of HCA2 regulates microglial responses to alleviate neurodegeneration in LPS-induced in vivo and in vitro models.
He D, Fu S, Ye B, Wang H, He Y, Li Z, Li J, Gao X, Liu D
Journal of neuroinflammation 2023 Mar 29;20(1):86
Journal of neuroinflammation 2023 Mar 29;20(1):86
Baicalin facilitates remyelination and suppresses neuroinflammation in rats with chronic cerebral hypoperfusion by activating Wnt/β-catenin and inhibiting NF-κB signaling.
Xiao Y, Guan T, Yang X, Xu J, Zhang J, Qi Q, Teng Z, Dong Y, Gao Y, Li M, Meng N, Lv P
Behavioural brain research 2023 Mar 28;442:114301
Behavioural brain research 2023 Mar 28;442:114301
Porcine Reproductive and Respiratory Syndrome Virus Modulates the Switch of Macrophage Polarization from M1 to M2 by Upregulating MoDC-Released sCD83.
Gong X, Ma T, Zhang Q, Wang Y, Song C, Lai M, Zhang C, Fang X, Chen X
Viruses 2023 Mar 17;15(3)
Viruses 2023 Mar 17;15(3)
Shared Genes of PPARG and NOS2 in Alzheimer's Disease and Ulcerative Colitis Drive Macrophages and Microglia Polarization: Evidence from Bioinformatics Analysis and Following Validation.
Dong L, Shen Y, Li H, Zhang R, Yu S, Wu Q
International journal of molecular sciences 2023 Mar 15;24(6)
International journal of molecular sciences 2023 Mar 15;24(6)
Corilagin ameliorates macrophages inflammation in atherosclerosis through TLR4-NFκB/MAPK pathway.
Meng D, Deng X, Wu Y, Wu J, Zhang Y, Zhang J, Zhao Y, Che Y
Heliyon 2023 Jun;9(6):e16960
Heliyon 2023 Jun;9(6):e16960
Dendritic cell-derived exosomal miR-3064-5p inhibits SIRT6/PCSK9 to protect the blood-brain barrier after subarachnoid hemorrhage.
Wang Y, Zhang L, Lv L, Zhou Z, Xi H
Journal of biochemical and molecular toxicology 2023 Jun;37(6):e23346
Journal of biochemical and molecular toxicology 2023 Jun;37(6):e23346
Human umbilical cord blood mononuclear cells ameliorate ischemic brain injury via promoting microglia/macrophages M2 polarization in MCAO Rats.
Li H, Xiao G, Tan X, Liu G, Xu Y, Gu S
Experimental brain research 2023 Jun;241(6):1585-1598
Experimental brain research 2023 Jun;241(6):1585-1598
A fully biodegradable polydioxanone occluder for ventricle septal defect closure.
Li Z, Kong P, Liu X, Feng S, Ouyang W, Wang S, Hu X, Xie Y, Zhang F, Zhang Y, Gao R, Wang W, Pan X
Bioactive materials 2023 Jun;24:252-262
Bioactive materials 2023 Jun;24:252-262
Alpha-ketoglutarate promotes alveolar bone regeneration by modulating M2 macrophage polarization.
Li Y, Liu L, Li Y, Song W, Shao B, Li H, Lin W, Li Q, Shuai X, Bai M, Zhao B, Guo Y, Yuan Q, Wang Y
Bone reports 2023 Jun;18:101671
Bone reports 2023 Jun;18:101671
Celastrol-encapsulated microspheres prepared by microfluidic electrospray for alleviating inflammatory pain.
Zheng H, Zhao C, Lu Y, Cao J, Zeng F, Wang H, Qin Z, Tao T
Biomaterials advances 2023 Jun;149:213398
Biomaterials advances 2023 Jun;149:213398
MFN2 deficiency affects calcium homeostasis in lung adenocarcinoma cells via downregulation of UCP4.
Zhang J, Pan L, Zhang Q, Zhao Y, Wang W, Lin N, Zhang S, Wu Q
FEBS open bio 2023 Jun;13(6):1107-1124
FEBS open bio 2023 Jun;13(6):1107-1124
Isobavachalcone ameliorates the progression of osteoarthritis by suppressing NF-κB signaling pathway.
Guo Q, Zhang M, Dong Y, Liu K, Wang D, Zheng J
International immunopharmacology 2023 Jun;119:110102
International immunopharmacology 2023 Jun;119:110102
Celastrol-loaded biomimetic nanodrug ameliorates APAP-induced liver injury through modulating macrophage polarization.
Zheng J, Yang N, Wan Y, Cheng W, Zhang G, Yu S, Yang B, Liu X, Chen X, Ding X, Wu L, Yu X
Journal of molecular medicine (Berlin, Germany) 2023 Jun;101(6):699-716
Journal of molecular medicine (Berlin, Germany) 2023 Jun;101(6):699-716
Preparation of nanocomposite membranes loaded with taxifolin liposome and its mechanism of wound healing in diabetic mice.
Ding Q, Ding C, Liu X, Zheng Y, Zhao Y, Zhang S, Sun S, Peng Z, Liu W
International journal of biological macromolecules 2023 Jun 30;241:124537
International journal of biological macromolecules 2023 Jun 30;241:124537
Endothelial progenitor cell-derived exosomes promote anti-inflammatory macrophages via SOCS3/JAK2/STAT3 axis and improve the outcome of spinal cord injury.
Yuan F, Peng W, Yang Y, Xu J, Liu Y, Xie Y, Huang T, Shi C, Ding Y, Li C, Qin T, Xie S, Zhu F, Lu H, Huang J, Hu J
Journal of neuroinflammation 2023 Jun 30;20(1):156
Journal of neuroinflammation 2023 Jun 30;20(1):156
Fusarium Mycotoxins Zearalenone and Deoxynivalenol Reduce Hepatocyte Innate Immune Response after the Listeria monocytogenes Infection by Inhibiting the TLR2/NFκB Signaling Pathway.
Feng N, Zhong F, Cai G, Zheng W, Zou H, Gu J, Yuan Y, Zhu G, Liu Z, Bian J
International journal of molecular sciences 2023 Jun 2;24(11)
International journal of molecular sciences 2023 Jun 2;24(11)
SENP3-mediated deSUMOylation of c-Jun facilitates microglia-induced neuroinflammation after cerebral ischemia and reperfusion injury.
Xia Q, Mao M, Zhan G, Luo Z, Zhao Y, Li X
iScience 2023 Jun 16;26(6):106953
iScience 2023 Jun 16;26(6):106953
The protective effects of Zhi-Gan-Cao-Tang against diabetic myocardial infarction injury and identification of its effective constituents.
Hu M, Li H, Ni S, Wang S
Journal of ethnopharmacology 2023 Jun 12;309:116320
Journal of ethnopharmacology 2023 Jun 12;309:116320
Targeting of Annexin A1 in Tumor-associated Macrophages as a therapeutic strategy for hepatocellular carcinoma.
Song Z, Wang X, Liu X, Luo Y, Qiu J, Yin A, Liu Y, Yi H, Xiao Z, Li A
Biochemical pharmacology 2023 Jul;213:115612
Biochemical pharmacology 2023 Jul;213:115612
Suramin ameliorates osteoarthritis by acting on the Nrf2/HO-1 and NF-κB signaling pathways in chondrocytes and promoting M2 polarization in macrophages.
Shen PC, Huang SH, Liu ZM, Lu CC, Chou SH, Tien YC
International immunopharmacology 2023 Jul;120:110295
International immunopharmacology 2023 Jul;120:110295
Selenium-Doped Mesoporous Bioactive Glass Regulates Macrophage Metabolism and Polarization by Scavenging ROS and Promotes Bone Regeneration In Vivo.
Chen D, Liang Z, Su Z, Huang J, Pi Y, Ouyang Y, Luo T, Guo L
ACS applied materials & interfaces 2023 Jul 26;15(29):34378-34396
ACS applied materials & interfaces 2023 Jul 26;15(29):34378-34396
Induced neural stem cells suppressed neuroinflammation by inhibiting the microglial pyroptotic pathway in intracerebral hemorrhage rats.
Liu J, Cao C, Jin Y, Wang Y, Ma X, Li J, Guo S, Yang J, Niu J, Liang X
iScience 2023 Jul 21;26(7):107022
iScience 2023 Jul 21;26(7):107022
Interleukin-1β Disruption Protects Male Mice From Heart Failure With Preserved Ejection Fraction Pathogenesis.
Srinivas BK, Bourdi A, O'Regan JD, Malavalli KD, Rhaleb NE, Belmadani S, Matrougui K
Journal of the American Heart Association 2023 Jul 18;12(14):e029668
Journal of the American Heart Association 2023 Jul 18;12(14):e029668
Pien Tze Huang attenuated acetaminophen-induced liver injury by autophagy mediated-NLRP3 inflammasome inhibition.
Zhao R, Zhang Q, Liu W, Lin Y, He Y, Chang D, Li S, Xu W, Lin Y, Zheng Y, Zhou X, Huang M
Journal of ethnopharmacology 2023 Jul 15;311:116285
Journal of ethnopharmacology 2023 Jul 15;311:116285
Crude polysaccharide from Danggui Buxue decoction enhanced the anti-tumor effect of gemcitabine by remodeling tumor-associated macrophages.
Zhan X, Xu X, Zhang P, Wang X, Hu Z, Zhao W, Hang T, Song M
International journal of biological macromolecules 2023 Jul 1;242(Pt 4):125063
International journal of biological macromolecules 2023 Jul 1;242(Pt 4):125063
Adenosine kinase promotes post-infarction cardiac repair by epigenetically maintaining reparative macrophage phenotype.
Zhang M, Wang C, Wang R, Xu J, Wang Z, Yan J, Cai Y, Li L, Huo Y, Dong S
Journal of molecular and cellular cardiology 2023 Jan;174:88-100
Journal of molecular and cellular cardiology 2023 Jan;174:88-100
IL-33/ST2 axis promotes remodeling of the extracellular matrix and drives protective microglial responses in the mouse model of perioperative neurocognitive disorders.
Li S, Liu H, Qian Y, Jiang L, Liu S, Liu Y, Liu C, Gu X
International immunopharmacology 2023 Jan;114:109479
International immunopharmacology 2023 Jan;114:109479
Dehydrocorydaline alleviates sleep deprivation-induced persistent postoperative pain in adolescent mice through inhibiting microglial P2Y(12) receptor expression in the spinal cord.
Yang H, Zhang Y, Duan Q, Ni K, Jiao Y, Zhu J, Sun J, Zhang W, Ma Z
Molecular pain 2023 Jan-Dec;19:17448069231216234
Molecular pain 2023 Jan-Dec;19:17448069231216234
Peptide-anchored neutrophil membrane-coated biomimetic nanodrug for targeted treatment of rheumatoid arthritis.
Yang N, Li M, Wu L, Song Y, Yu S, Wan Y, Cheng W, Yang B, Mou X, Yu H, Zheng J, Li X, Yu X
Journal of nanobiotechnology 2023 Jan 13;21(1):13
Journal of nanobiotechnology 2023 Jan 13;21(1):13
Melatonin Attenuates Mitochondrial Damage in Aristolochic Acid-Induced Acute Kidney Injury.
Sun J, Pan J, Liu Q, Cheng J, Tang Q, Ji Y, Cheng K, Wang R, Liu L, Wang D, Wu N, Zheng X, Li J, Zhang X, Zhu Z, Ding Y, Zheng F, Li J, Zhang Y, Yuan Y
Biomolecules & therapeutics 2023 Jan 1;31(1):97-107
Biomolecules & therapeutics 2023 Jan 1;31(1):97-107
Hypoxia-Inducible Factor-1α Protects Against Intervertebral Disc Degeneration Through Antagonizing Mitochondrial Oxidative Stress.
Yang W, Jia C, Liu L, Fu Y, Wu Y, Liu Z, Yu R, Ma X, Gong A, Liu F, Xia Y, Hou Y, Li Y, Zhang L
Inflammation 2023 Feb;46(1):270-284
Inflammation 2023 Feb;46(1):270-284
Castor1 overexpression regulates microglia M1/M2 polarization via inhibiting mTOR pathway.
Hu H, Lu X, Huang L, He Y, Liu X, Wang Y, Duan C
Metabolic brain disease 2023 Feb;38(2):699-708
Metabolic brain disease 2023 Feb;38(2):699-708
ADP-ribose transferase PARP16 mediated-unfolded protein response contributes to neuronal cell damage in cerebral ischemia/reperfusion.
Wang J, Xu J, Dong Y, Su Z, Su H, Cheng Q, Liu X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Feb;37(2):e22788
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Feb;37(2):e22788
Antidepression of Xingpijieyu formula targets gut microbiota derived from depressive disorder.
Li Y, Yang L, Li J, Gao W, Zhao Z, Dong K, Duan W, Dai B, Guo R
CNS neuroscience & therapeutics 2023 Feb;29(2):669-681
CNS neuroscience & therapeutics 2023 Feb;29(2):669-681
Exosomes Derived from AT2R-Overexpressing BMSC Prevent Restenosis After Carotid Artery Injury by Attenuating the Injury-Induced Neointimal Hyperplasia.
Zou X, Liao Y, Liu Z, Xu X, Sun W, Qin H, Wang H, Liu J, Jing T
Journal of cardiovascular translational research 2023 Feb;16(1):112-126
Journal of cardiovascular translational research 2023 Feb;16(1):112-126
Iso-seco-tanapartholide induces p62 covalent oligomerization to activate KEAP1-NRF2 redox pathway in rheumatoid arthritis.
Zhu D, Kong M, Chen C, Luo J, Kong L
International immunopharmacology 2023 Feb;115:109689
International immunopharmacology 2023 Feb;115:109689
Stevioside targets the NF-κB and MAPK pathways for inhibiting inflammation and apoptosis of chondrocytes and ameliorates osteoarthritis in vivo.
Cai T, Ye H, Jiang H, Lin C, Lou C, Wang W, Yan Z, Xue X, Pan X, Lin J
International immunopharmacology 2023 Feb;115:109683
International immunopharmacology 2023 Feb;115:109683
Matrix metalloproteinase-21 promotes metastasis via increasing the recruitment and M2 polarization of macrophages in HCC.
Zhou J, Liu L, Hu X, Feng R, Zhao N, Zhang L, Hu W, Zhang J, Huang S, Liu L, Li W, Shan Y, Jin J
Cancer science 2023 Feb;114(2):423-435
Cancer science 2023 Feb;114(2):423-435
The upregulation of peripheral blood polyamine metabolites spermidine and spermine in children with hand, foot, mouth disease is related to enterovirus 71 capsid protein VP1, but not VP4.
Li C, Zhang W, Chang X, Di X, Xie Q, Lin B, Zhang H, Ye Z, Lan M, Lian J, Zhang H, Qiu X, Zeng J, Huang M
Translational pediatrics 2023 Feb 28;12(2):194-207
Translational pediatrics 2023 Feb 28;12(2):194-207
Exosomal RBP4 potentiated hepatic lipid accumulation and inflammation in high-fat-diet-fed mice by promoting M1 polarization of Kupffer cells.
Yao JM, Ying HZ, Zhang HH, Qiu FS, Wu JQ, Yu CH
Free radical biology & medicine 2023 Feb 1;195:58-73
Free radical biology & medicine 2023 Feb 1;195:58-73
A cell-penetrating peptide exerts therapeutic effects against ischemic stroke by mediating the lysosomal degradation of sirtuin 5.
Xia Q, Zhang X, Zhan G, Zheng L, Mao M, Zhao Y, Zhao Y, Li X
MedComm 2023 Dec;4(6):e436
MedComm 2023 Dec;4(6):e436
Identification of Clec7a as the therapeutic target of rTMS in alleviating Parkinson's disease: targeting neuroinflammation.
Chen XY, Feng SN, Bao Y, Zhou YX, Ba F
Biochimica et biophysica acta. Molecular basis of disease 2023 Dec;1869(8):166814
Biochimica et biophysica acta. Molecular basis of disease 2023 Dec;1869(8):166814
Salvianolic acid A alleviates heart failure with preserved ejection fraction via regulating TLR/Myd88/TRAF/NF-κB and p38MAPK/CREB signaling pathways.
Dawuti A, Sun S, Wang R, Gong D, Liu R, Kong D, Yuan T, Zhou J, Lu Y, Wang S, Du G, Fang L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec;168:115837
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec;168:115837
Ginsenoside Rb1 protects hippocampal neurons in depressed rats based on mitophagy-regulated astrocytic pyroptosis.
Li Y, Li J, Yang L, Ren F, Dong K, Zhao Z, Duan W, Wei W, Guo R
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Dec;121:155083
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Dec;121:155083
MiR-146b-5p enriched bioinspired exosomes derived from fucoidan-directed induction mesenchymal stem cells protect chondrocytes in osteoarthritis by targeting TRAF6.
Lou C, Jiang H, Lin Z, Xia T, Wang W, Lin C, Zhang Z, Fu H, Iqbal S, Liu H, Lin J, Wang J, Pan X, Xue X
Journal of nanobiotechnology 2023 Dec 18;21(1):486
Journal of nanobiotechnology 2023 Dec 18;21(1):486
Neuron-Derived Exosomes Promote the Recovery of Spinal Cord Injury by Modulating Nerve Cells in the Cellular Microenvironment of the Lesion Area.
Xu Y, Zhu ZH, Xu X, Sun HT, Zheng HM, Zhang JL, Wang HH, Fang JW, Liu YZ, Huang LL, Song ZW, Liu JB
Molecular neurobiology 2023 Aug;60(8):4502-4516
Molecular neurobiology 2023 Aug;60(8):4502-4516
Mechanism of ligusticum cycloprolactam against neuroinflammation based on network pharmacology and experimental verification.
Gao J, Su G, Chen W, Wu Q, Liu J, Liu J, Chai M, Dong Y, Wang H, Chen L, Zhang Z, Wang M
Clinical and experimental pharmacology & physiology 2023 Aug;50(8):647-663
Clinical and experimental pharmacology & physiology 2023 Aug;50(8):647-663
Inhibition of NF-κB Signaling-Mediated Crosstalk Between Macrophages and Preosteoblasts by Metformin Alleviates Trauma-Induced Heterotopic Ossification.
Hou J, Chen J, Fan J, Tang Z, Zhou W, Lin H
Inflammation 2023 Aug;46(4):1414-1429
Inflammation 2023 Aug;46(4):1414-1429
Structurally dynamic self-healable hydrogel cooperatively inhibits intestinal inflammation and promotes mucosal repair for enhanced ulcerative colitis treatment.
Ge X, Wen H, Fei Y, Xue R, Cheng Z, Li Y, Cai K, Li L, Li M, Luo Z
Biomaterials 2023 Aug;299:122184
Biomaterials 2023 Aug;299:122184
Profilin1 Regulates Trophoblast Invasion and Macrophage Differentiation.
Chen X, Song QL, Wang JY, Ji R, Li ZH, Cao ML, Mu XF, Guo DY, Zhang Y, Yang J
The American journal of pathology 2023 Aug;193(8):1059-1071
The American journal of pathology 2023 Aug;193(8):1059-1071
ROS Scavenging Nanozyme Modulates Immunosuppression for Sensitized Cancer Immunotherapy.
Mo W, Liu S, Zhao X, Wei F, Li Y, Sheng X, Cao W, Ding M, Zhang W, Chen X, Meng L, Yao S, Diao W, Wei H, Guo H
Advanced healthcare materials 2023 Aug;12(21):e2300191
Advanced healthcare materials 2023 Aug;12(21):e2300191
Tumor-secreted GRP78 induces M2 polarization of macrophages by promoting lipid catabolism.
Tian J, Zhang L, La X, Fan X, Li A, Wu C, An Y, Yan S, Dong X, Wu H, Li Z
Cellular signalling 2023 Aug;108:110719
Cellular signalling 2023 Aug;108:110719
Role of omentin-1 in susceptibility to anxiety and depression like behaviors.
Ji L, Zhang L, Liang Z, Zhong S, Liu X, Liu Z, Poon WS, Song Y, Chen B, Wang R
Molecular and cellular endocrinology 2023 Aug 20;574:111990
Molecular and cellular endocrinology 2023 Aug 20;574:111990
Electroacupuncture relieves chronic pain by promoting microglia M2 polarization in lumbar disc herniation rats.
Yang JX, Zhu J, Ni K, Yang HK, Zhang HL, Ma ZL
Neuroreport 2023 Aug 2;34(12):638-648
Neuroreport 2023 Aug 2;34(12):638-648
TNFSF14/LIGHT promotes cardiac fibrosis and atrial fibrillation vulnerability via PI3Kγ/SGK1 pathway-dependent M2 macrophage polarisation.
Wu Y, Zhan S, Chen L, Sun M, Li M, Mou X, Zhang Z, Xu L, Xu Y
Journal of translational medicine 2023 Aug 14;21(1):544
Journal of translational medicine 2023 Aug 14;21(1):544
PARP16-Mediated Stabilization of Amyloid Precursor Protein mRNA Exacerbates Alzheimer's Disease Pathogenesis.
Wang J, Cheng Q, Zhang Y, Hong C, Liu J, Liu X, Chang J
Aging and disease 2023 Aug 1;14(4):1458-1471
Aging and disease 2023 Aug 1;14(4):1458-1471
Prenatally VPA exposure is likely to cause autistic-like behavior in the rats offspring via TREM2 down-regulation to affect the microglial activation and synapse alterations.
Luo L, Chen J, Wu Q, Yuan B, Hu C, Yang T, Wei H, Li T
Environmental toxicology and pharmacology 2023 Apr;99:104090
Environmental toxicology and pharmacology 2023 Apr;99:104090
Activating α7nAChR helps post-myocardial infarction healing by regulating macrophage polarization via the STAT3 signaling pathway.
Niu XH, Liu RH, Lv X, He RL, Lv FZ, Wu SJ, Li XQ, Li L, Lin JF
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2023 Apr;72(4):879-892
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2023 Apr;72(4):879-892
Hederagenin Suppresses Inflammation and Cartilage Degradation to Ameliorate the Progression of Osteoarthritis: An In vivo and In vitro Study.
Shen Y, Teng L, Qu Y, Huang Y, Peng Y, Tang M, Fu Q
Inflammation 2023 Apr;46(2):655-678
Inflammation 2023 Apr;46(2):655-678
Ioversol Induced Microglia Proinflammatory Activation and Oxidative Stress in Rats.
Li T, Zhao L, Fan H, Chen Z, Li Y, Dang M, Lu Z, Lu J, Huang Q, Wang H, Wu S, Zhang G, Kuang F
Neurotoxicity research 2023 Apr;41(2):149-165
Neurotoxicity research 2023 Apr;41(2):149-165
Abamectin causes toxicity to the carp respiratory system by triggering oxidative stress, inflammation, and apoptosis and inhibiting autophagy.
Feng H, Zhou P, Liu F, Zhang W, Yang H, Li X, Dong J
Environmental science and pollution research international 2023 Apr;30(19):55200-55213
Environmental science and pollution research international 2023 Apr;30(19):55200-55213
Lipid-accumulated reactive astrocytes promote disease progression in epilepsy.
Chen ZP, Wang S, Zhao X, Fang W, Wang Z, Ye H, Wang MJ, Ke L, Huang T, Lv P, Jiang X, Zhang Q, Li L, Xie ST, Zhu JN, Hang C, Chen D, Liu X, Yan C
Nature neuroscience 2023 Apr;26(4):542-554
Nature neuroscience 2023 Apr;26(4):542-554
Mechanisms regarding respiratory toxicity triggered by accumulation of ROS in carp exposed to difenoconazole.
Feng H, Chen H, Qiang J, Xu B, Wu X, Pan E, Yang H, Li X, Zhang J, Dong J
Pesticide biochemistry and physiology 2023 Apr;191:105343
Pesticide biochemistry and physiology 2023 Apr;191:105343
Vagus nerve stimulation is a potential treatment for ischemic stroke.
Liu YL, Wang SR, Ma JX, Yu LH, Jia GW
Neural regeneration research 2023 Apr;18(4):825-831
Neural regeneration research 2023 Apr;18(4):825-831
Cardamonin alleviates chondrocytes inflammation and cartilage degradation of osteoarthritis by inhibiting ferroptosis via p53 pathway.
Gong Z, Wang Y, Li L, Li X, Qiu B, Hu Y
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Apr;174:113644
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Apr;174:113644
Autophagy-mediated circHIPK2 promotes lipopolysaccharide-induced astrocytic inflammation via SIGMAR1.
Huang R, Cai L, Ma X, Shen K
International immunopharmacology 2023 Apr;117:109907
International immunopharmacology 2023 Apr;117:109907
Analysis and verification of the circRNA regulatory network RNO_CIRCpedia_ 4214/RNO-miR-667-5p/Msr1 axis as a potential ceRNA promoting macrophage M2-like polarization in spinal cord injury.
Cao J, Pan C, Zhang J, Chen Q, Li T, He D, Cheng X
BMC genomics 2023 Apr 5;24(1):181
BMC genomics 2023 Apr 5;24(1):181
Menstrual blood-derived endometrial stem cells alleviate neuroinflammation by modulating M1/M2 polarization in cell and rat Parkinson's disease models.
Li H, Wei J, Zhang Z, Li J, Ma Y, Zhang P, Lin J
Stem cell research & therapy 2023 Apr 13;14(1):85
Stem cell research & therapy 2023 Apr 13;14(1):85
Regulatory Effects of Three-Dimensional Cultured Lipopolysaccharide-Pretreated Periodontal Ligament Stem Cell-Derived Secretome on Macrophages.
Su Y, Ai S, Shen Y, Cheng W, Xu C, Sui L, Zhao Y
International journal of molecular sciences 2023 Apr 10;24(8)
International journal of molecular sciences 2023 Apr 10;24(8)
SGLT2i alleviates epicardial adipose tissue inflammation by modulating ketone body-glyceraldehyde-3-phosphate dehydrogenase malonylation pathway.
Li L, Hua C, Liu X, Wang Y, Zhao L, Zhang Y, Wang L, Su P, Yang MF, Xie B
Journal of cardiovascular medicine (Hagerstown, Md.) 2023 Apr 1;24(4):232-243
Journal of cardiovascular medicine (Hagerstown, Md.) 2023 Apr 1;24(4):232-243
Functional OCT angiography reveals early retinal neurovascular dysfunction in diabetes with capillary resolution.
Liu K, Zhu T, Gao M, Yin X, Zheng R, Yan Y, Gao L, Ding Z, Ye J, Li P
Biomedical optics express 2023 Apr 1;14(4):1670-1684
Biomedical optics express 2023 Apr 1;14(4):1670-1684
Collagen peptide promotes DSS-induced colitis by disturbing gut microbiota and regulation of macrophage polarization.
Li X, Cui L, Feng G, Yu S, Shao G, He N, Li S
Frontiers in nutrition 2022;9:957391
Frontiers in nutrition 2022;9:957391
Iron Chelation Remits Memory Deficits Caused by the High-Fat Diet in a Mouse Model of Alzheimer's Disease.
Xiao Y, Gong X, Deng R, Liu W, Yang Y, Wang X, Wang J, Bao J, Shu X
Journal of Alzheimer's disease : JAD 2022;86(4):1959-1971
Journal of Alzheimer's disease : JAD 2022;86(4):1959-1971
Neferine Suppresses Experimental Colitis-Associated Colorectal Cancer by Inhibition of NF-[Formula: see text]B p65 and STAT3.
Zhou Y, Xiang S, Zheng H, Hou Y, Wang Y, Li CC, Wu Q, Shi J, Chen X
The American journal of Chinese medicine 2022;50(5):1387-1400
The American journal of Chinese medicine 2022;50(5):1387-1400
A Network Pharmacology Approach for Uncovering the Antitumor Effects and Potential Mechanisms of the Sijunzi Decoction for the Treatment of Gastric Cancer.
Ding P, Guo Y, Wang C, Chen J, Guo C, Liu H, Shi Q
Evidence-based complementary and alternative medicine : eCAM 2022;2022:9364313
Evidence-based complementary and alternative medicine : eCAM 2022;2022:9364313
In Vitro Immunomodulatory Effects of Inonotus obliquus Extracts on Resting M0 Macrophages and LPS-Induced M1 Macrophages.
Shen D, Feng Y, Zhang X, Liu J, Gong L, Liao H, Li R
Evidence-based complementary and alternative medicine : eCAM 2022;2022:8251344
Evidence-based complementary and alternative medicine : eCAM 2022;2022:8251344
Astragali Radix-Coptis Rhizoma Herb Pair Attenuates Atherosclerosis in ApoE-/- Mice by Regulating the M1/M2 and Th1/Th2 Immune Balance and Activating the STAT6 Signaling Pathway.
Li Z, Ma D, Wang Y, Wu S, Wang L, Jiang Y, Zhang Y, Li X
Evidence-based complementary and alternative medicine : eCAM 2022;2022:7421265
Evidence-based complementary and alternative medicine : eCAM 2022;2022:7421265
Mechanical Stretch Promotes Macrophage Polarization and Inflammation via the RhoA-ROCK/NF-κB Pathway.
Tu PC, Pan YL, Liang ZQ, Yang GL, Wu CJ, Zeng L, Wang LN, Sun J, Liu MM, Yuan YF, Guo Y, Ma Y
BioMed research international 2022;2022:6871269
BioMed research international 2022;2022:6871269
Macrophages with Different Polarization Phenotypes Influence Cementoblast Mineralization through Exosomes.
Zhao Y, Huang Y, Liu H, Tan K, Wang R, Jia L, Li W
Stem cells international 2022;2022:4185972
Stem cells international 2022;2022:4185972
Grape Seed Proanthocyanidins Exert a Neuroprotective Effect by Regulating Microglial M1/M2 Polarisation in Rats with Spinal Cord Injury.
Liu WZ, Ma ZJ, Kang JH, Lin AX, Wang ZH, Chen HW, Guo XD, He XG, Kang XW
Mediators of inflammation 2022;2022:2579003
Mediators of inflammation 2022;2022:2579003
Corynoline Alleviates Osteoarthritis Development via the Nrf2/NF-κB Pathway.
Li S, Shi Y, Zhang S, Li H, Ye Z, Kong J, Hong W, Tu Y, Ren J, Meftah Z, Xie C, Wang X, Zhang X
Oxidative medicine and cellular longevity 2022;2022:2188145
Oxidative medicine and cellular longevity 2022;2022:2188145
Honokiol Ameliorates DSS-Induced Mouse Colitis by Inhibiting Inflammation and Oxidative Stress and Improving the Intestinal Barrier.
Wang L, Wang J
Oxidative medicine and cellular longevity 2022;2022:1755608
Oxidative medicine and cellular longevity 2022;2022:1755608
Supplementation with dietary omega-3 PUFA mitigates fetal brain inflammation and mitochondrial damage caused by high doses of sodium nitrite in maternal rats.
Sun J, Zhang W
PloS one 2022;17(3):e0266084
PloS one 2022;17(3):e0266084
TREM2 improves neurological dysfunction and attenuates neuroinflammation, TLR signaling and neuronal apoptosis in the acute phase of intracerebral hemorrhage.
Liu S, Cao X, Wu Z, Deng S, Fu H, Wang Y, Liu F
Frontiers in aging neuroscience 2022;14:967825
Frontiers in aging neuroscience 2022;14:967825
A construction and comprehensive analysis of the immune-related core ceRNA network and infiltrating immune cells in peripheral arterial occlusive disease.
Chen Z, Xu J, Zha B, Li J, Li Y, Ouyang H
Frontiers in genetics 2022;13:951537
Frontiers in genetics 2022;13:951537
Icariin protects vertebral endplate chondrocytes against apoptosis and degeneration via activating Nrf-2/HO-1 pathway.
Shao Y, Sun L, Yang G, Wang W, Liu X, Du T, Chen F, Jing X, Cui X
Frontiers in pharmacology 2022;13:937502
Frontiers in pharmacology 2022;13:937502
Brevilin A Ameliorates Acute Lung Injury and Inflammation Through Inhibition of NF-κB Signaling via Targeting IKKα/β.
Liu L, Chen X, Jiang Y, Yuan Y, Yang L, Hu Q, Tang J, Meng X, Xie C, Shen X
Frontiers in pharmacology 2022;13:911157
Frontiers in pharmacology 2022;13:911157
Characterization of Fatty Acid Metabolism-Related Genes Landscape for Predicting Prognosis and Aiding Immunotherapy in Glioma Patients.
Jiang F, Luo F, Zeng N, Mao Y, Tang X, Wang J, Hu Y, Wu C
Frontiers in immunology 2022;13:902143
Frontiers in immunology 2022;13:902143
The Protective Effect of Evodiamine in Osteoarthritis: An In Vitro and In Vivo Study in Mice Model.
Xian S, Lin Z, Zhou C, Wu X
Frontiers in pharmacology 2022;13:899108
Frontiers in pharmacology 2022;13:899108
Polydatin activates the Nrf2/HO-1 signaling pathway to protect cisplatin-induced hearing loss in guinea pigs.
Li D, Zhao H, Xu P, Lin Q, Zhao T, Li C, Cui ZK, Tian G
Frontiers in pharmacology 2022;13:887833
Frontiers in pharmacology 2022;13:887833
Neutrophil Extracellular Traps Regulate HMGB1 Translocation and Kupffer Cell M1 Polarization During Acute Liver Transplantation Rejection.
Liu Y, Pu X, Qin X, Gong J, Huang Z, Luo Y, Mou T, Zhou B, Shen A, Wu Z
Frontiers in immunology 2022;13:823511
Frontiers in immunology 2022;13:823511
Dehydrocostus Lactone Suppresses Dextran Sulfate Sodium-Induced Colitis by Targeting the IKKα/β-NF-κB and Keap1-Nrf2 Signalling Pathways.
Yuan Y, Hu Q, Liu L, Xie F, Yang L, Li Y, Zhang C, Chen H, Tang J, Shen X
Frontiers in pharmacology 2022;13:817596
Frontiers in pharmacology 2022;13:817596
Erratum: Addendum: A novel N-Arylpyridone compound alleviates the inflammatory and fibrotic reaction of silicosis by inhibiting the ASK1-p38 pathway and regulating macrophage polarization.
Fan M, Xiao H, Song D, Zhu L, Zhang J, Zhang X, Wang J, Dai H, Wang C
Frontiers in pharmacology 2022;13:1108989
Frontiers in pharmacology 2022;13:1108989
Network analysis and experimental pharmacology study explore the protective effects of Isoliquiritigenin on 5-fluorouracil-Induced intestinal mucositis.
Liao YF, Luo FL, Tang SS, Huang JW, Yang Y, Wang S, Jiang TY, Man Q, Liu S, Wu YY
Frontiers in pharmacology 2022;13:1014160
Frontiers in pharmacology 2022;13:1014160
Catalpol ameliorates CFA-induced inflammatory pain by targeting spinal cord and peripheral inflammation.
Zhao B, Fu J, Ni H, Xu L, Xu C, He Q, Ni C, Wang Y, Kuang J, Tang M, Shou Q, Yao M
Frontiers in pharmacology 2022;13:1010483
Frontiers in pharmacology 2022;13:1010483
TGFBI secreted by tumor-associated macrophages promotes glioblastoma stem cell-driven tumor growth via integrin αvβ5-Src-Stat3 signaling.
Peng P, Zhu H, Liu D, Chen Z, Zhang X, Guo Z, Dong M, Wan L, Zhang P, Liu G, Zhang S, Dong F, Hu F, Cheng F, Huang S, Guo D, Zhang B, Yu X, Wan F
Theranostics 2022;12(9):4221-4236
Theranostics 2022;12(9):4221-4236
Heparin binding epidermal growth factor-like growth factor is a prognostic marker correlated with levels of macrophages infiltrated in lung adenocarcinoma.
Van Hiep N, Sun WL, Feng PH, Lin CW, Chen KY, Luo CS, Dung LN, Van Quyet H, Wu SM, Lee KY
Frontiers in oncology 2022;12:963896
Frontiers in oncology 2022;12:963896
Scutellarin Protects Against Mitochondrial Reactive Oxygen Species-Dependent NLRP3 Inflammasome Activation to Attenuate Intervertebral Disc Degeneration.
Wang Z, Zhang P, Zhao Y, Yu F, Wang S, Liu K, Cheng X, Shi J, He Q, Xia Y, Cheng L
Frontiers in bioengineering and biotechnology 2022;10:883118
Frontiers in bioengineering and biotechnology 2022;10:883118
Polyvinylpyrrolidone-Modified Taxifolin Liposomes Promote Liver Repair by Modulating Autophagy to Inhibit Activation of the TLR4/NF-κB Signaling Pathway.
Ding Q, Liu W, Liu X, Ding C, Zhao Y, Dong L, Chen H, Sun S, Zhang Y, Zhang J, Wu M
Frontiers in bioengineering and biotechnology 2022;10:860515
Frontiers in bioengineering and biotechnology 2022;10:860515
A Composite Hydrogel Containing Mesoporous Silica Nanoparticles Loaded With Artemisia argyi Extract for Improving Chronic Wound Healing.
Xue L, Deng T, Guo R, Peng L, Guo J, Tang F, Lin J, Jiang S, Lu H, Liu X, Deng L
Frontiers in bioengineering and biotechnology 2022;10:825339
Frontiers in bioengineering and biotechnology 2022;10:825339
CXCR3 antagonist AMG487 ameliorates experimental autoimmune prostatitis by diminishing Th1 cell differentiation and inhibiting macrophage M1 phenotypic activation.
Hua X, Zhang J, Ge S, Liu H, Du H, Niu Q, Chen X, Yang C, Zhang L, Liang C
The Prostate 2022 Sep;82(13):1223-1236
The Prostate 2022 Sep;82(13):1223-1236
Serum-derived exosomes from SD rats induce inflammation in macrophages through the mTOR pathway.
Wang Y, Liu YP, Sun ZB, Deng WH, Yuan XY, Lei YD, Cai Y, Huang L, Zhang ZH
Journal of applied toxicology : JAT 2022 Sep;42(9):1524-1532
Journal of applied toxicology : JAT 2022 Sep;42(9):1524-1532
Inhibition of Mer exacerbates early brain injury by regulating microglia/macrophage phenotype after subarachnoid hemorrhage in mice.
Tan X, Zheng Y, Zeng H, Peng Y, Yu X, Cao S
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2022 Sep;31(9):106659
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2022 Sep;31(9):106659
Vagus nerve stimulation promotes the M1-to-M2 transition via inhibition of TLR4/NF-κB in microglial to rescue the reperfusion injury.
Zhang L, Zhang X, Liu Y, Wang S, Jia G
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2022 Sep;31(9):106596
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2022 Sep;31(9):106596
Protective effects of budesonide on LPS-induced podocyte injury by modulating macrophage M1/M2 polarization: Evidence from in vitro and in silico studies.
Zhang X, Wang G, Shen D, Feng Y, Zhang Y, Zhang C, Li Y, Liao H
Experimental and therapeutic medicine 2022 Sep;24(3):589
Experimental and therapeutic medicine 2022 Sep;24(3):589
Colchicine improves severe acute pancreatitis-induced acute lung injury by suppressing inflammation, apoptosis and oxidative stress in rats.
Zhang D, Li L, Li J, Wei Y, Tang J, Man X, Liu F
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Sep;153:113461
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Sep;153:113461
Tubuloside B, isolated from Cistanche tubulosa, a promising agent against M1 macrophage activation via synergistically targeting Mob1 and ERK1/2.
Xiao L, Yao J, Miao Y, Ou B, Wang J, Huang Y, Zhou B, Ge L, Tian J, Zeng X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Sep;153:113414
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Sep;153:113414
Magnoflorine attenuates inflammatory responses in RA by regulating the PI3K/Akt/NF-κB and Keap1-Nrf2/HO-1 signalling pathways in vivo and in vitro.
Shen Y, Fan X, Qu Y, Tang M, Huang Y, Peng Y, Fu Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Sep;104:154339
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Sep;104:154339
Omentin-1 promoted proliferation and ameliorated inflammation, apoptosis, and degeneration in human nucleus pulposus cells.
Cabral VLF, Wang F, Peng X, Gao J, Zhou Z, Sun R, Bao J, Wu X
Archives of gerontology and geriatrics 2022 Sep-Oct;102:104748
Archives of gerontology and geriatrics 2022 Sep-Oct;102:104748
Therapeutic efficacy of human adipose mesenchymal stem cells in Crohn's colon fibrosis is improved by IFN-γ and kynurenic acid priming through indoleamine 2,3-dioxygenase-1 signaling.
Ye Y, Zhang X, Su D, Ren Y, Cheng F, Yao Y, Shi G, Ji Y, Chen S, Shi P, Dai L, Su X, Deng H
Stem cell research & therapy 2022 Sep 8;13(1):465
Stem cell research & therapy 2022 Sep 8;13(1):465
Akebia Saponin D Inhibits the Inflammatory Reaction by Inhibiting the IL-6-STAT3-DNMT3b Axis and Activating the Nrf2 Pathway.
Luo JF, Zhou H, Lio CK
Molecules (Basel, Switzerland) 2022 Sep 22;27(19)
Molecules (Basel, Switzerland) 2022 Sep 22;27(19)
β2-Microglobulin Maintains Glioblastoma Stem Cells and Induces M2-like Polarization of Tumor-Associated Macrophages.
Li D, Zhang Q, Li L, Chen K, Yang J, Dixit D, Gimple RC, Ci S, Lu C, Hu L, Gao J, Shan D, Li Y, Zhang J, Shi Z, Gu D, Yuan W, Wu Q, Yang K, Zhao L, Qiu Z, Lv D, Gao W, Yang H, Lin F, Wang Q, Man J, Li C, Tao W, Agnihotri S, Qian X, Shi Y, You Y, Zhang N, Rich JN, Wang X
Cancer research 2022 Sep 16;82(18):3321-3334
Cancer research 2022 Sep 16;82(18):3321-3334
Flufenamic acid improves survival and neurologic outcome after successful cardiopulmonary resuscitation in mice.
Chen J, Chang Y, Zhu J, Peng Y, Li Z, Zhang K, Zhang Y, Lin C, Lin Z, Pan S, Huang K
Journal of neuroinflammation 2022 Sep 1;19(1):214
Journal of neuroinflammation 2022 Sep 1;19(1):214
Aucubin promoted neuron functional recovery by suppressing inflammation and neuronal apoptosis in a spinal cord injury model.
Xiao S, Zhong N, Yang Q, Li A, Tong W, Zhang Y, Yao G, Wang S, Liu J, Liu Z
International immunopharmacology 2022 Oct;111:109163
International immunopharmacology 2022 Oct;111:109163
Chicoric acid attenuates tumor necrosis factor-α-induced inflammation and apoptosis via the Nrf2/HO-1, PI3K/AKT and NF-κB signaling pathways in C28/I2 cells and ameliorates the progression of osteoarthritis in a rat model.
Qu Y, Shen Y, Teng L, Huang Y, Yang Y, Jian X, Fan S, Wu P, Fu Q
International immunopharmacology 2022 Oct;111:109129
International immunopharmacology 2022 Oct;111:109129
Injectable and reactive oxygen species-scavenging gelatin hydrogel promotes neural repair in experimental traumatic brain injury.
Zhang D, Chang R, Ren Y, He Y, Guo S, Guan F, Yao M
International journal of biological macromolecules 2022 Oct 31;219:844-863
International journal of biological macromolecules 2022 Oct 31;219:844-863
PCSK9 promotes the progression and metastasis of colon cancer cells through regulation of EMT and PI3K/AKT signaling in tumor cells and phenotypic polarization of macrophages.
Wang L, Li S, Luo H, Lu Q, Yu S
Journal of experimental & clinical cancer research : CR 2022 Oct 14;41(1):303
Journal of experimental & clinical cancer research : CR 2022 Oct 14;41(1):303
Astaxanthin attenuates osteoarthritis progression via inhibiting ferroptosis and regulating mitochondrial function in chondrocytes.
Wang X, Liu Z, Peng P, Gong Z, Huang J, Peng H
Chemico-biological interactions 2022 Oct 1;366:110148
Chemico-biological interactions 2022 Oct 1;366:110148
Difenoconazole disrupts the blood-brain barrier and results in neurotoxicity in carp by inhibiting the Nrf2 pathway mediated ROS accumulation.
Liu F, Wang Y, Chen L, Bello BK, Zhang T, Yang H, Li X, Pan E, Feng H, Dong J
Ecotoxicology and environmental safety 2022 Oct 1;244:114081
Ecotoxicology and environmental safety 2022 Oct 1;244:114081
OIT3 mediates macrophage polarization and facilitates hepatocellular carcinoma progression.
Yang S, Zhang J, Xu Y, Wang J, Zhao H, Lei J, Zhou Y, Chen Y, Wu L, Zhou M, Zheng L, Ji X, Li Y
Cancer immunology, immunotherapy : CII 2022 Nov;71(11):2677-2689
Cancer immunology, immunotherapy : CII 2022 Nov;71(11):2677-2689
Caffeic acid phenethyl ester attenuates osteoarthritis progression by activating NRF2/HO‑1 and inhibiting the NF‑κB signaling pathway.
Sun W, Xie W, Huang D, Cui Y, Yue J, He Q, Jiang L, Xiong J, Sun W, Yi Q
International journal of molecular medicine 2022 Nov;50(5)
International journal of molecular medicine 2022 Nov;50(5)
Vindoline ameliorates intestinal barrier damage in Crohn's disease mice through MAPK signaling pathway.
Zhang X, Zuo L, Geng Z, Song X, Li J, Ge S, Jiang Y, Yang Z, Liu G, Zhao Y, Zhao H, Yu L, Hu J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Nov;36(11):e22589
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Nov;36(11):e22589
Macrophage targeted triptolide micelles capable of cGAS-STING pathway inhibition for rheumatoid arthritis treatment.
Xu A, Yang R, Zhang M, Wang X, Di Y, Jiang B, Di Y, Zhou Z, Zhou L
Journal of drug targeting 2022 Nov;30(9):961-972
Journal of drug targeting 2022 Nov;30(9):961-972
Biomimetic cell membrane-coated glucose/oxygen-exhausting nanoreactor for remodeling tumor microenvironment in targeted hypoxic tumor therapy.
Guo H, Zhang W, Wang L, Shao Z, Huang X
Biomaterials 2022 Nov;290:121821
Biomaterials 2022 Nov;290:121821
N-acetylserotonin protects PC12 cells from hydrogen peroxide induced damage through ROS mediated PI3K / AKT pathway.
Kang J, Wang Y, Guo X, He X, Liu W, Chen H, Wang Z, Lin A, Kang X
Cell cycle (Georgetown, Tex.) 2022 Nov;21(21):2268-2282
Cell cycle (Georgetown, Tex.) 2022 Nov;21(21):2268-2282
An increase in Semaphorin 3A biases the axonal direction and induces an aberrant dendritic arborization in an in vitro model of human neural progenitor differentiation.
Ferretti G, Romano A, Sirabella R, Serafini S, Maier TJ, Matrone C
Cell & bioscience 2022 Nov 8;12(1):182
Cell & bioscience 2022 Nov 8;12(1):182
Gut fungi enhances immunosuppressive function of myeloid-derived suppressor cells by activating PKM2-dependent glycolysis to promote colorectal tumorigenesis.
Zhang Z, Zheng Y, Chen Y, Yin Y, Chen Y, Chen Q, Hou Y, Shen S, Lv M, Wang T
Experimental hematology & oncology 2022 Nov 8;11(1):88
Experimental hematology & oncology 2022 Nov 8;11(1):88
5-Methoxyflavone alleviates LPS-mediated lung injury by promoting Nrf2-mediated the suppression of NOX4/TLR4 axis in bronchial epithelial cells and M1 polarization in macrophages.
Liang P, Wang L, Yang S, Pan X, Li J, Zhang Y, Liang Y, Li J, Zhou B
Journal of inflammation (London, England) 2022 Nov 30;19(1):24
Journal of inflammation (London, England) 2022 Nov 30;19(1):24
Carbon dots derived from folic acid attenuates osteoarthritis by protecting chondrocytes through NF-κB/MAPK pathway and reprogramming macrophages.
Jin Y, Zhang Q, Qin X, Liu Z, Li Z, Zhong X, Xia L, He J, Fang B
Journal of nanobiotechnology 2022 Nov 3;20(1):469
Journal of nanobiotechnology 2022 Nov 3;20(1):469
Amination Potentially Augments the Ameliorative Effect of Curcumin on Inhibition of the IL-6/Stat3/c-Myc Pathway and Gut Microbial Modulation in Colitis-Associated Tumorigenesis.
Koh YC, Tsai YW, Lee PS, Nagabhushanam K, Ho CT, Pan MH
Journal of agricultural and food chemistry 2022 Nov 23;70(46):14744-14754
Journal of agricultural and food chemistry 2022 Nov 23;70(46):14744-14754
Orally Administered Ginkgolide C Attenuates DSS-Induced Colitis by Maintaining Gut Barrier Integrity, Inhibiting Inflammatory Responses, and Regulating Intestinal Flora.
Xu D, Zhuang L, Gao S, Ma H, Cheng J, Liu J, Liu D, Fu S, Hu G
Journal of agricultural and food chemistry 2022 Nov 23;70(46):14718-14731
Journal of agricultural and food chemistry 2022 Nov 23;70(46):14718-14731
Golgi Phosphoprotein 3 Mediates Radiation-Induced Bystander Effect via ERK/EGR1/TNF-α Signal Axis.
Qin F, Chen G, Yu KN, Yang M, Cao W, Kong P, Peng S, Sun M, Nie L, Han W
Antioxidants (Basel, Switzerland) 2022 Nov 1;11(11)
Antioxidants (Basel, Switzerland) 2022 Nov 1;11(11)
Antioxidant and Immunomodulatory Properties of Partially purified Exopolysaccharide from Lactobacillus Casei Isolated from Chinese Northeast Sauerkraut.
Xu X, Qiao Y, Peng Q, Shi B, Dia VP
Immunological investigations 2022 May;51(4):748-765
Immunological investigations 2022 May;51(4):748-765
Inhalation of MSC-EVs is a noninvasive strategy for ameliorating acute lung injury.
Zhao R, Wang L, Wang T, Xian P, Wang H, Long Q
Journal of controlled release : official journal of the Controlled Release Society 2022 May;345:214-230
Journal of controlled release : official journal of the Controlled Release Society 2022 May;345:214-230
Biomimetic Immunosuppressive Exosomes that Inhibit Cytokine Storms Contribute to the Alleviation of Sepsis.
Li Y, Zhang H, Chen C, Qiao K, Li Z, Han J, Han X, Li K, Lai K, Liu N, Li A, Xiao N, Zhang Y, Zhao X, Gao W, Zhang Y, Liu H, Sun T
Advanced materials (Deerfield Beach, Fla.) 2022 May;34(19):e2108476
Advanced materials (Deerfield Beach, Fla.) 2022 May;34(19):e2108476
Naringenin promoted spinal microglia M2 polarization in rat model of cancer-induced bone pain via regulating AMPK/PGC-1α signaling axis.
Ge MM, Li DY, Wang L, Zhang LQ, Liu DQ, Tian YK, Ye DW, Liu ZH, Zhou YQ, Yang H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 May;149:112912
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 May;149:112912
Enhanced immunogenicity of the tuberculosis subunit Rv0572c vaccine delivered in DMT liposome adjuvant as a BCG-booster.
Mao L, Xu L, Wang X, Xing Y, Wang J, Zhang Y, Yuan W, Du J, Shi Z, Ma J, Zhang J, Zhang X, Wang X
Tuberculosis (Edinburgh, Scotland) 2022 May;134:102186
Tuberculosis (Edinburgh, Scotland) 2022 May;134:102186
Facile fabrication of a biocompatible composite gel with sustained release of aspirin for bone regeneration.
Zhang Y, Dou X, Zhang L, Wang H, Zhang T, Bai R, Sun Q, Wang X, Yu T, Wu D, Han B, Deng X
Bioactive materials 2022 May;11:130-139
Bioactive materials 2022 May;11:130-139
Growth differentiation factor 11 induces skeletal muscle atrophy via a STAT3-dependent mechanism in pulmonary arterial hypertension.
Xiang G, Ying K, Jiang P, Jia M, Sun Y, Li S, Wu X, Hao S
Skeletal muscle 2022 May 6;12(1):10
Skeletal muscle 2022 May 6;12(1):10
Targeted delivery of methotrexate by modified yeast β-glucan nanoparticles for rheumatoid arthritis therapy.
Chen H, Sun Y, Xu X, Ye Q
Carbohydrate polymers 2022 May 15;284:119183
Carbohydrate polymers 2022 May 15;284:119183
Hippocampal overexpression of TREM2 ameliorates high fat diet induced cognitive impairment and modulates phenotypic polarization of the microglia.
Wu M, Liao M, Huang R, Chen C, Tian T, Wang H, Li J, Li J, Sun Y, Wu C, Li Q, Xiao X
Genes & diseases 2022 Mar;9(2):401-414
Genes & diseases 2022 Mar;9(2):401-414
Inhibition of IRE1 suppresses the catabolic effect of IL-1β on nucleus pulposus cell and prevents intervertebral disc degeneration in vivo.
Kang H, Dong Y, Peng R, Liu H, Guo Q, Song K, Zhu M, Yu K, Wu W, Li F
Biochemical pharmacology 2022 Mar;197:114932
Biochemical pharmacology 2022 Mar;197:114932
Neutrophil membrane-mimicking nanodecoys with intrinsic anti-inflammatory properties alleviate sepsis-induced acute liver injury and lethality in a mouse endotoxemia model.
Xiao Y, Ren C, Chen G, Shang P, Song X, You G, Yan S, Yao Y, Zhou H
Materials today. Bio 2022 Mar;14:100244
Materials today. Bio 2022 Mar;14:100244
Interleukin-10 genetically modified clinical-grade mesenchymal stromal cells markedly reinforced functional recovery after spinal cord injury via directing alternative activation of macrophages.
Gao T, Huang F, Wang W, Xie Y, Wang B
Cellular & molecular biology letters 2022 Mar 17;27(1):27
Cellular & molecular biology letters 2022 Mar 17;27(1):27
Icariin alleviates uveitis by targeting peroxiredoxin 3 to modulate retinal microglia M1/M2 phenotypic polarization.
Wang G, Li X, Li N, Wang X, He S, Li W, Fan W, Li R, Liu J, Hou S
Redox biology 2022 Jun;52:102297
Redox biology 2022 Jun;52:102297
Effects of ALA-PDT on the macrophages in wound healing and its related mechanisms in vivo and in vitro.
Li L, Yang Y, Yang Z, Zheng M, Luo G, He W, Yin R
Photodiagnosis and photodynamic therapy 2022 Jun;38:102816
Photodiagnosis and photodynamic therapy 2022 Jun;38:102816
Methionine strengthens anti-inflammation of rice protein via depressing NF-κB activation and stimulating Msr expression in rats fed cholesterol-enriched diets.
Wang Z, Liang M, Liu B, Yang L
Food science and biotechnology 2022 Jun;31(6):745-758
Food science and biotechnology 2022 Jun;31(6):745-758
Farrerol alleviates collagenase-induced tendinopathy by inhibiting ferroptosis in rats.
Wu Y, Qian J, Li K, Li W, Yin W, Jiang H
Journal of cellular and molecular medicine 2022 Jun;26(12):3483-3494
Journal of cellular and molecular medicine 2022 Jun;26(12):3483-3494
Transposon-mediated glial cell line-derived neurotrophic factor overexpression in human adipose tissue-derived mesenchymal stromal cells: A potential approach for neuroregenerative medicine?
Rasińska J, Klein C, Stahn L, Maidhof F, Pfeffer A, Schreyer S, Gossen M, Kurtz A, Steiner B, Hemmati-Sadeghi S
Journal of tissue engineering and regenerative medicine 2022 Jun;16(6):515-529
Journal of tissue engineering and regenerative medicine 2022 Jun;16(6):515-529
Robust drug bioavailability and safety for rheumatoid arthritis therapy using D-amino acids-based supramolecular hydrogels.
Ma S, Gu S, Zhang J, Qi W, Lin Z, Zhai W, Zhan J, Li Q, Cai Y, Lu Y
Materials today. Bio 2022 Jun;15:100296
Materials today. Bio 2022 Jun;15:100296
MicroRNA-200c-5p targets NIMA Related Kinase 7 (NEK7) to inhibit NOD-like receptor 3 (NLRP3) inflammasome activation, MODE-K cell pyroptosis, and inflammatory bowel disease in mice.
Wu G, Zhang D, Yang L, Wu Q, Yuan L
Molecular immunology 2022 Jun;146:57-68
Molecular immunology 2022 Jun;146:57-68
The circadian clock protein Rev-erbα provides neuroprotection and attenuates neuroinflammation against Parkinson's disease via the microglial NLRP3 inflammasome.
Kou L, Chi X, Sun Y, Han C, Wan F, Hu J, Yin S, Wu J, Li Y, Zhou Q, Zou W, Xiong N, Huang J, Xia Y, Wang T
Journal of neuroinflammation 2022 Jun 6;19(1):133
Journal of neuroinflammation 2022 Jun 6;19(1):133
DKK3 ameliorates neuropathic pain via inhibiting ASK-1/JNK/p-38-mediated microglia polarization and neuroinflammation.
Zhang LQ, Gao SJ, Sun J, Li DY, Wu JY, Song FH, Liu DQ, Zhou YQ, Mei W
Journal of neuroinflammation 2022 Jun 3;19(1):129
Journal of neuroinflammation 2022 Jun 3;19(1):129
Rutin Inhibits Ox-LDL-Mediated Macrophage Inflammation and Foam Cell Formation by Inducing Autophagy and Modulating PI3K/ATK Signaling.
Li B, Ji Y, Yi C, Wang X, Liu C, Wang C, Lu X, Xu X, Wang X
Molecules (Basel, Switzerland) 2022 Jun 29;27(13)
Molecules (Basel, Switzerland) 2022 Jun 29;27(13)
Implantation of a nerve protector embedded with human GMSC-derived Schwann-like cells accelerates regeneration of crush-injured rat sciatic nerves.
Zhang Q, Burrell JC, Zeng J, Motiwala FI, Shi S, Cullen DK, Le AD
Stem cell research & therapy 2022 Jun 20;13(1):263
Stem cell research & therapy 2022 Jun 20;13(1):263
Progranulin deficiency promotes persistent neuroinflammation and causes regional pathology in the hippocampus following traumatic brain injury.
Zheng X, Mi T, Wang R, Zhang Z, Li W, Zhao J, Yang P, Xia H, Mao Q
Glia 2022 Jul;70(7):1317-1336
Glia 2022 Jul;70(7):1317-1336
Construction and comprehensive analysis of a lncRNA-mRNA interactive network to reveal a potential lncRNA for hepatic encephalopathy development.
Zhang C, Ni W, Zhu Y, Lin J, Li H, Zhao Z, Wang K, Huo H, Luo M
Human cell 2022 Jul;35(4):1060-1070
Human cell 2022 Jul;35(4):1060-1070
Epigallocatechin-3-O-gallate ameliorates oxidative stress-induced chondrocyte dysfunction and exerts chondroprotective effects via the Keap1/Nrf2/ARE signaling pathway.
Zhu W, Tang H, Cao L, Zhang J, Li J, Ma D, Guo C
Chemical biology & drug design 2022 Jul;100(1):108-120
Chemical biology & drug design 2022 Jul;100(1):108-120
Melatonin ameliorates Parkinson's disease via regulating microglia polarization in a RORα-dependent pathway.
Li J, Liu H, Wang X, Xia Y, Huang J, Wang T, Lin Z, Xiong N
NPJ Parkinson's disease 2022 Jul 8;8(1):90
NPJ Parkinson's disease 2022 Jul 8;8(1):90
Extracellular vesicle miR-32 derived from macrophage promotes arterial calcification in mice with type 2 diabetes via inhibiting VSMC autophagy.
Cao J, Chen C, Chen Q, Gao Y, Zhao Z, Yuan Q, Li A, Yang S, He Y, Zu X, Liu J
Journal of translational medicine 2022 Jul 6;20(1):307
Journal of translational medicine 2022 Jul 6;20(1):307
Wharton's jelly mesenchymal stem cell-derived small extracellular vesicles as natural nanoparticles to attenuate cartilage injury via microRNA regulation.
Chen P, Tang S, Gao H, Zhang H, Chen C, Fang Z, Peng G, Weng H, Chen A, Zhang C, Qiu Z, Li S, Chen J, Chen L, Chen X
International journal of pharmaceutics 2022 Jul 25;623:121952
International journal of pharmaceutics 2022 Jul 25;623:121952
SENP6 induces microglial polarization and neuroinflammation through de-SUMOylation of Annexin-A1 after cerebral ischaemia-reperfusion injury.
Mao M, Xia Q, Zhan GF, Chu QJ, Li X, Lian HK
Cell & bioscience 2022 Jul 22;12(1):113
Cell & bioscience 2022 Jul 22;12(1):113
Adenosine kinase (ADK) inhibition with ABT-702 induces ADK protein degradation and a distinct form of sustained cardioprotection.
Wölkart G, Stessel H, Fassett E, Teschl E, Friedl K, Trummer M, Schrammel A, Kollau A, Mayer B, Fassett J
European journal of pharmacology 2022 Jul 15;927:175050
European journal of pharmacology 2022 Jul 15;927:175050
Beneficial effects of QTC-4-MeOBnE in an LPS-induced mouse model of depression and cognitive impairments: The role of blood-brain barrier permeability, NF-κB signaling, and microglial activation.
Fronza MG, Baldinotti R, Fetter J, Rosa SG, Sacramento M, Nogueira CW, Alves D, Praticò D, Savegnago L
Brain, behavior, and immunity 2022 Jan;99:177-191
Brain, behavior, and immunity 2022 Jan;99:177-191
Resveratrol Improves Synaptic Plasticity in Hypoxic-Ischemic Brain Injury in Neonatal Mice via Alleviating SIRT1/NF-κB Signaling-Mediated Neuroinflammation.
Peng X, Wang J, Peng J, Jiang H, Le K
Journal of molecular neuroscience : MN 2022 Jan;72(1):113-125
Journal of molecular neuroscience : MN 2022 Jan;72(1):113-125
Maresin 1 protects against lipopolysaccharide/d-galactosamine-induced acute liver injury by inhibiting macrophage pyroptosis and inflammatory response.
Yang W, Tao K, Zhang P, Chen X, Sun X, Li R
Biochemical pharmacology 2022 Jan;195:114863
Biochemical pharmacology 2022 Jan;195:114863
Wilforlide A ameliorates the progression of rheumatoid arthritis by inhibiting M1 macrophage polarization.
Cao Y, Liu J, Huang C, Tao Y, Wang Y, Chen X, Huang D
Journal of pharmacological sciences 2022 Jan;148(1):116-124
Journal of pharmacological sciences 2022 Jan;148(1):116-124
Injectable hyaluronic acid hydrogel loaded with BMSC and NGF for traumatic brain injury treatment.
Wang L, Zhang D, Ren Y, Guo S, Li J, Ma S, Yao M, Guan F
Materials today. Bio 2022 Jan;13:100201
Materials today. Bio 2022 Jan;13:100201
Extracellular vesicle-mediated delivery of circDYM alleviates CUS-induced depressive-like behaviours.
Yu X, Bai Y, Han B, Ju M, Tang T, Shen L, Li M, Yang L, Zhang Z, Hu G, Chao J, Zhang Y, Yao H
Journal of extracellular vesicles 2022 Jan;11(1):e12185
Journal of extracellular vesicles 2022 Jan;11(1):e12185
Artesunate attenuates atherosclerosis by inhibiting macrophage M1-like polarization and improving metabolism.
Wang X, Du H, Li X
International immunopharmacology 2022 Jan;102:108413
International immunopharmacology 2022 Jan;102:108413
The ethanol extract of flower buds of Tussilago farfara L. attenuates cigarette smoke-induced lung inflammation through regulating NLRP3 inflammasome, Nrf2, and NF-κB.
Xu LT, Wang T, Fang KL, Zhao Y, Wang XN, Ren DM, Shen T
Journal of ethnopharmacology 2022 Jan 30;283:114694
Journal of ethnopharmacology 2022 Jan 30;283:114694
Inhibition of Noncanonical Ca(2+) Oscillation/Calcineurin/GSK-3β Pathway Contributes to Anti-Inflammatory Effect of Sigma-1 Receptor Activation.
Gao T, Gao C, Liu Z, Wang Y, Jia X, Tian H, Lu Q, Guo L
Neurochemical research 2022 Feb;47(2):264-278
Neurochemical research 2022 Feb;47(2):264-278
Enhancement of anti-inflammatory effect of cattle bile by fermentation and its inhibition of neuroinflammation on microglia by inhibiting NLRP3 inflammasome.
Pei Y, Cheng F, Li W, Yu Q, Ma C, Zou Y, Xu T, Liu S, Zhang S, Wang Q
Journal of bioscience and bioengineering 2022 Feb;133(2):146-154
Journal of bioscience and bioengineering 2022 Feb;133(2):146-154
One-Step Synthesis of Multifunctional Chitosan Hydrogel for Full-Thickness Wound Closure and Healing.
Guo S, Yao M, Zhang D, He Y, Chang R, Ren Y, Guan F
Advanced healthcare materials 2022 Feb;11(4):e2101808
Advanced healthcare materials 2022 Feb;11(4):e2101808
Gut microbiota-derived butyrate regulates gut mucus barrier repair by activating the macrophage/WNT/ERK signaling pathway.
Liang L, Liu L, Zhou W, Yang C, Mai G, Li H, Chen Y
Clinical science (London, England : 1979) 2022 Feb 25;136(4):291-307
Clinical science (London, England : 1979) 2022 Feb 25;136(4):291-307
Transcutaneous delivery of mung bean-derived nanoparticles for amelioration of psoriasis-like skin inflammation.
Sun H, Zhao Y, Zhang P, Zhai S, Li W, Cui J
Nanoscale 2022 Feb 24;14(8):3040-3048
Nanoscale 2022 Feb 24;14(8):3040-3048
METTL3 overexpression aggravates LPS-induced cellular inflammation in mouse intestinal epithelial cells and DSS-induced IBD in mice.
Yang L, Wu G, Wu Q, Peng L, Yuan L
Cell death discovery 2022 Feb 14;8(1):62
Cell death discovery 2022 Feb 14;8(1):62
Sphingosine-1 phosphate receptor 1 contributes to central sensitization in recurrent nitroglycerin-induced chronic migraine model.
Pan Q, Wang Y, Tian R, Wen Q, Qin G, Zhang D, Chen L, Zhang Y, Zhou J
The journal of headache and pain 2022 Feb 10;23(1):25
The journal of headache and pain 2022 Feb 10;23(1):25
Immune-responsive gene 1/itaconate activates nuclear factor erythroid 2-related factor 2 in microglia to protect against spinal cord injury in mice.
Ni L, Xiao J, Zhang D, Shao Z, Huang C, Wang S, Wu Y, Tian N, Sun L, Wu A, Zhou Y, Wang X, Zhang X
Cell death & disease 2022 Feb 10;13(2):140
Cell death & disease 2022 Feb 10;13(2):140
Caffeine treatment started before injury reduces hypoxic-ischemic white-matter damage in neonatal rats by regulating phenotypic microglia polarization.
Yang L, Yu X, Zhang Y, Liu N, Xue X, Fu J
Pediatric research 2022 Dec;92(6):1543-1554
Pediatric research 2022 Dec;92(6):1543-1554
Indoleamine 2,3-dioxygenase mediates the therapeutic effects of adipose-derived stromal/stem cells in experimental periodontitis by modulating macrophages through the kynurenine-AhR-NRF2 pathway.
Li H, Yuan Y, Chen H, Dai H, Li J
Molecular metabolism 2022 Dec;66:101617
Molecular metabolism 2022 Dec;66:101617
Catalpol relieved angiotensin II-induced blood-brain barrier destruction via inhibiting the TLR4 pathway in brain endothelial cells.
Xia Y, Lu YW, Hao RJ, Yu GR
Pharmaceutical biology 2022 Dec;60(1):2210-2218
Pharmaceutical biology 2022 Dec;60(1):2210-2218
Shenlian extract attenuates myocardial ischaemia-reperfusion injury via inhibiting M1 macrophage polarization by silencing miR-155.
Song M, Cui X, Zhang J, Li Y, Li J, Zang Y, Li Q, Yang Q, Chen Y, Cai W, Weng X, Wang Y, Zhu X
Pharmaceutical biology 2022 Dec;60(1):2011-2024
Pharmaceutical biology 2022 Dec;60(1):2011-2024
Exosome modification to better alleviates endoplasmic reticulum stress induced chondrocyte apoptosis and osteoarthritis.
Wang Y, Fan A, Lu L, Pan Z, Ma M, Luo S, Liu Z, Yang L, Cai J, Yin F
Biochemical pharmacology 2022 Dec;206:115343
Biochemical pharmacology 2022 Dec;206:115343
L-Methionine inhibits 4-hydroxy-2-nonenal accumulation and suppresses inflammation in growing rats.
Wang Z, Liang M, Li H, Liu B, Yang L
Nutrition research and practice 2022 Dec;16(6):729-744
Nutrition research and practice 2022 Dec;16(6):729-744
Pexidartinib (PLX3397) through restoring hippocampal synaptic plasticity ameliorates social isolation-induced mood disorders.
Wang L, Wang X, Deng L, Zhang H, He B, Cao W, Cui Y
International immunopharmacology 2022 Dec;113(Pt B):109436
International immunopharmacology 2022 Dec;113(Pt B):109436
Freshwater Clam Extract Attenuates Indomethacin-Induced Gastric Damage In Vitro and In Vivo.
Isnain FS, Liao NC, Tsai HY, Zhao YJ, Huang CH, Hsu JL, Wardani AK, Chen YK
Foods (Basel, Switzerland) 2022 Dec 28;12(1)
Foods (Basel, Switzerland) 2022 Dec 28;12(1)
Anti-Amnesic Effect of Synbiotic Supplementation Containing Corni fructus and Limosilactobacillus reuteri in DSS-Induced Colitis Mice.
Lee HL, Kim JM, Moon JH, Kim MJ, Jeong HR, Go MJ, Kim HJ, Eo HJ, Lee U, Heo HJ
International journal of molecular sciences 2022 Dec 21;24(1)
International journal of molecular sciences 2022 Dec 21;24(1)
Astragaloside IV attenuates IL-1β-induced intervertebral disc degeneration through inhibition of the NF-κB pathway.
Tian Y, Chu X, Huang Q, Guo X, Xue Y, Deng W
Journal of orthopaedic surgery and research 2022 Dec 16;17(1):545
Journal of orthopaedic surgery and research 2022 Dec 16;17(1):545
Betaine supplementation alleviates dextran sulfate sodium-induced colitis via regulating the inflammatory response, enhancing the intestinal barrier, and altering gut microbiota.
Zhao N, Yang Y, Chen C, Jing T, Hu Y, Xu H, Wang S, He Y, Liu E, Cui J
Food & function 2022 Dec 13;13(24):12814-12826
Food & function 2022 Dec 13;13(24):12814-12826
Augmented PFKFB3-mediated glycolysis by interferon-γ promotes inflammatory M1 polarization through the JAK2/STAT1 pathway in local vascular inflammation in Takayasu arteritis.
Chen R, Wang J, Dai X, Wu S, Huang Q, Jiang L, Kong X
Arthritis research & therapy 2022 Dec 12;24(1):266
Arthritis research & therapy 2022 Dec 12;24(1):266
Aloe polymeric acemannan inhibits the cytokine storm in mouse pneumonia models by modulating macrophage metabolism.
Li L, Xu W, Luo Y, Lao C, Tong X, Du J, Huang B, Li D, Chen J, Ye H, Cong F, Guo X, Li J
Carbohydrate polymers 2022 Dec 1;297:120032
Carbohydrate polymers 2022 Dec 1;297:120032
Macrophage depletion blocks congenital SARM1-dependent neuropathy.
Dingwall CB, Strickland A, Yum SW, Yim AK, Zhu J, Wang PL, Yamada Y, Schmidt RE, Sasaki Y, Bloom AJ, DiAntonio A, Milbrandt J
The Journal of clinical investigation 2022 Dec 1;132(23)
The Journal of clinical investigation 2022 Dec 1;132(23)
Upregulation of RCAN1.4 by HIF1α alleviates OGD-induced inflammatory response in astrocytes.
Yang X, Yun Y, Wang P, Zhao J, Sun X
Annals of clinical and translational neurology 2022 Aug;9(8):1224-1240
Annals of clinical and translational neurology 2022 Aug;9(8):1224-1240
Cornuside Is a Potential Agent against Alzheimer's Disease via Orchestration of Reactive Astrocytes.
Shi JZ, Zheng XM, Zhou YF, Yun LY, Luo DM, Hao JJ, Liu PF, Zhang WK, Xu JK, Yan Y, Xie XM, He YY, Pang XB
Nutrients 2022 Aug 3;14(15)
Nutrients 2022 Aug 3;14(15)
DNA Origami as a Nanomedicine for Targeted Rheumatoid Arthritis Therapy through Reactive Oxygen Species and Nitric Oxide Scavenging.
Ma Y, Lu Z, Jia B, Shi Y, Dong J, Jiang S, Li Z
ACS nano 2022 Aug 23;16(8):12520-12531
ACS nano 2022 Aug 23;16(8):12520-12531
Capsaicin ameliorates inflammation in a TRPV1-independent mechanism by inhibiting PKM2-LDHA-mediated Warburg effect in sepsis.
Zhang Q, Luo P, Xia F, Tang H, Chen J, Zhang J, Liu D, Zhu Y, Liu Y, Gu L, Zheng L, Li Z, Yang F, Dai L, Liao F, Xu C, Wang J
Cell chemical biology 2022 Aug 18;29(8):1248-1259.e6
Cell chemical biology 2022 Aug 18;29(8):1248-1259.e6
Phenolic Acids from Fructus Chebulae Immaturus Alleviate Intestinal Ischemia-Reperfusion Injury in Mice through the PPARα/NF-κB Pathway.
Liu J, Li B, Liu J, Qiu F, Diao Y, Lei Y, Liu J, Zhang W
Molecules (Basel, Switzerland) 2022 Aug 16;27(16)
Molecules (Basel, Switzerland) 2022 Aug 16;27(16)
Rice protein suppresses 4-hydroxy-2-nonenal-induced inflammation owing to methionine availability.
Wang Z, Liang M, Li H, Liu B, Yang L
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 2022 Aug 1;47(8):826-838
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 2022 Aug 1;47(8):826-838
Resolution of inflammation is disturbed in acute ischemic stroke with diabetes mellitus and rescued by resolvin D2 treatment.
Tang X, Liu L, Miao Z, Zhang J, Cai X, Zhao BQ, Chen G, Schultzberg M, Zhao Y, Wang X
Free radical biology & medicine 2022 Aug 1;188:194-205
Free radical biology & medicine 2022 Aug 1;188:194-205
San-Wu-Huang-Qin decoction attenuates tumorigenesis and mucosal barrier impairment in the AOM/DSS model by targeting gut microbiome.
Zhou Y, Feng Y, Cen R, Hou X, Yu H, Sun J, Zhou L, Ji Q, Zhao L, Wang Y, Li Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Apr;98:153966
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Apr;98:153966
Tangeretin suppresses osteoarthritis progression via the Nrf2/NF-κB and MAPK/NF-κB signaling pathways.
Shi Y, Chen J, Li S, Wu Y, Yu C, Ni L, Xiao J, Shao Z, Zhu H, Wang J, Wang X, Zhang X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Apr;98:153928
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Apr;98:153928
Amelioration of Neuropathic Pain and Attenuation of Neuroinflammation Responses by Tetrahydropalmatine Through the p38MAPK/NF-κB/iNOS Signaling Pathways in Animal and Cellular Models.
Hu C, He M, Chen M, Xu Q, Li S, Cui Y, Qiu X, Tian W
Inflammation 2022 Apr;45(2):891-903
Inflammation 2022 Apr;45(2):891-903
Lipoxin A4 regulates M1/M2 macrophage polarization via FPR2-IRF pathway.
Yuan J, Lin F, Chen L, Chen W, Pan X, Bai Y, Cai Y, Lu H
Inflammopharmacology 2022 Apr;30(2):487-498
Inflammopharmacology 2022 Apr;30(2):487-498
Itaconate attenuates osteoarthritis by inhibiting STING/NF-κB axis in chondrocytes and promoting M2 polarization in macrophages.
Ni L, Lin Z, Hu S, Shi Y, Jiang Z, Zhao J, Zhou Y, Wu Y, Tian N, Sun L, Wu A, Pan Z, Zhang X, Wang X
Biochemical pharmacology 2022 Apr;198:114935
Biochemical pharmacology 2022 Apr;198:114935
Undescribed ecdysteroids and phenolic glycosides from the roots of Cyathula officinalis Kuan and their anti-inflammatory activity in LPS-induced RAW 264.7 macrophages in vitro.
Yang LF, Teng L, Huang YH, Tang M, Liao W, Fu Q
Phytochemistry 2022 Apr;196:113101
Phytochemistry 2022 Apr;196:113101
Ellagic acid attenuates interleukin-1β-induced oxidative stress and exerts protective effects on chondrocytes through the Kelch-like ECH-associated protein 1 (Keap1)/ Nuclear factor erythroid 2-related factor 2 (Nrf2) pathway.
Zhu W, Tang H, Li J, Guedes RM, Cao L, Guo C
Bioengineered 2022 Apr;13(4):9233-9247
Bioengineered 2022 Apr;13(4):9233-9247
High proportion strontium-doped micro-arc oxidation coatings enhance early osseointegration of titanium in osteoporosis by anti-oxidative stress pathway.
Shen X, Fang K, Ru Yie KH, Zhou Z, Shen Y, Wu S, Zhu Y, Deng Z, Ma P, Ma J, Liu J
Bioactive materials 2022 Apr;10:405-419
Bioactive materials 2022 Apr;10:405-419
MicroRNA-146a-5p-modified human umbilical cord mesenchymal stem cells enhance protection against diabetic nephropathy in rats through facilitating M2 macrophage polarization.
Zhang Y, Le X, Zheng S, Zhang K, He J, Liu M, Tu C, Rao W, Du H, Ouyang Y, Li C, Wu D
Stem cell research & therapy 2022 Apr 27;13(1):171
Stem cell research & therapy 2022 Apr 27;13(1):171
Inhibition of Notch activity suppresses hyperglycemia-augmented polarization of macrophages to the M1 phenotype and alleviates acute pancreatitis.
Hu N, Zhang X, Zhang X, Guan Y, He R, Xue E, Zhang X, Deng W, Yu J, Wang W, Shi Q
Clinical science (London, England : 1979) 2022 Apr 14;136(7):455-471
Clinical science (London, England : 1979) 2022 Apr 14;136(7):455-471
Urolithin A promotes mitophagy and suppresses NLRP3 inflammasome activation in lipopolysaccharide-induced BV2 microglial cells and MPTP-induced Parkinson's disease model.
Qiu J, Chen Y, Zhuo J, Zhang L, Liu J, Wang B, Sun D, Yu S, Lou H
Neuropharmacology 2022 Apr 1;207:108963
Neuropharmacology 2022 Apr 1;207:108963
lncRNA Gm16410 Mediates PM(2).(5)-Induced Macrophage Activation via PI3K/AKT Pathway.
Xu J, Xu H, Ma K, Wang Y, Niu B, Zhang L, Li F
Frontiers in cell and developmental biology 2021;9:618045
Frontiers in cell and developmental biology 2021;9:618045
Characterization of an Aging-Based Diagnostic Gene Signature and Molecular Subtypes With Diverse Immune Infiltrations in Atherosclerosis.
Zhao L, Lv F, Zheng Y, Yan L, Cao X
Frontiers in molecular biosciences 2021;8:792540
Frontiers in molecular biosciences 2021;8:792540
Inhibition of Sphingosine-1-Phosphate Receptor 2 Prevents Thoracic Aortic Dissection and Rupture.
Pan G, Liao M, Dai Y, Li Y, Yan X, Mai W, Liu J, Liao Y, Qiu Z, Zhou Z
Frontiers in cardiovascular medicine 2021;8:748486
Frontiers in cardiovascular medicine 2021;8:748486
Gut Immunity and Microbiota Dysbiosis Are Associated with Altered Bile Acid Metabolism in LPS-Challenged Piglets.
Xiao X, Cheng Y, Fu J, Lu Z, Wang F, Jin M, Zong X, Wang Y
Oxidative medicine and cellular longevity 2021;2021:6634821
Oxidative medicine and cellular longevity 2021;2021:6634821
Deficiency of IKKα in Macrophages Mitigates Fibrosis Progression in the Kidney after Renal Ischemia-Reperfusion Injury.
Zhang F, Fan L, Zhang H, Huang WJ, Sun D, Pan BB, Wan X, Cao CC
Journal of immunology research 2021;2021:5521051
Journal of immunology research 2021;2021:5521051
TNF-Like Ligand 1 Aberrance Aggravates Nonalcoholic Steatohepatitis via M1 Macrophage Polarization.
Luo Y, Guo J, Jia W, Wu M, Yin F, Niu G, Shih DQ, Targan SR, Zhang X
Oxidative medicine and cellular longevity 2021;2021:3877617
Oxidative medicine and cellular longevity 2021;2021:3877617
Retinal Neuropathy in IGT Stage of OLETF Rats: Another Characteristic Change of Diabetic Retinopathy.
Guo Z, Sun X, Yang J, Xie J, Zhong F, Li X, Zhang Y, Han F, Yang X, Yang S, Zhou W, Chang B
Journal of diabetes research 2021;2021:3181347
Journal of diabetes research 2021;2021:3181347
ALDH2/SIRT1 Contributes to Type 1 and Type 2 Diabetes-Induced Retinopathy through Depressing Oxidative Stress.
He M, Long P, Chen T, Li K, Wei D, Zhang Y, Wang W, Hu Y, Ding Y, Wen A
Oxidative medicine and cellular longevity 2021;2021:1641717
Oxidative medicine and cellular longevity 2021;2021:1641717
Albumin-encapsulated Nanoparticles of Naproxen Platinum(IV) Complexes with Inflammation Inhibitory Competence Displaying Effective Antitumor Activities in vitro and in vivo.
Li L, Chen Y, Wang Q, Li Z, Liu Z, Hua X, Han J, Chang C, Wang Z, Li D
International journal of nanomedicine 2021;16:5513-5529
International journal of nanomedicine 2021;16:5513-5529
Rosuvastatin Nanomicelles Target Neuroinflammation and Improve Neurological Deficit in a Mouse Model of Intracerebral Hemorrhage.
Zi L, Zhou W, Xu J, Li J, Li N, Xu J, You C, Wang C, Tian M
International journal of nanomedicine 2021;16:2933-2947
International journal of nanomedicine 2021;16:2933-2947
GDC-0575, a CHK1 Inhibitor, Impairs the Development of Colitis and Colitis-Associated Cancer by Inhibiting CCR2(+) Macrophage Infiltration in Mice.
Li M, Huang T, Li X, Shi Z, Sheng Y, Hu M, Song K
OncoTargets and therapy 2021;14:2661-2672
OncoTargets and therapy 2021;14:2661-2672
Upregulation of Neuronal Cylindromatosis Expression is Essential for Electroacupuncture-Mediated Alleviation of Neuroinflammatory Injury by Regulating Microglial Polarization in Rats Subjected to Focal Cerebral Ischemia/Reperfusion.
Lin X, Zhan J, Jiang J, Ren Y
Journal of inflammation research 2021;14:2061-2078
Journal of inflammation research 2021;14:2061-2078
Irradiation-Induced Activated Microglia Affect Brain Metastatic Colonization of NSCLC Cells via miR-9/CDH1 Axis.
Jin Y, Kang Y, Peng X, Yang L, Li Q, Mei Q, Chen X, Hu G, Tang Y, Yuan X
OncoTargets and therapy 2021;14:1911-1922
OncoTargets and therapy 2021;14:1911-1922
Histone Deacetylase 6 Regulates the Activation of M1 Macrophages by the Glycolytic Pathway During Acute Liver Failure.
Wang Y, Li X, Chen Q, Jiao F, Shi C, Pei M, Wang L, Gong Z
Journal of inflammation research 2021;14:1473-1485
Journal of inflammation research 2021;14:1473-1485
Mesenchymal Stem Cells Overexpressing ACE2 Favorably Ameliorate LPS-Induced Inflammatory Injury in Mammary Epithelial Cells.
Yan S, Ye P, Aleem MT, Chen X, Xie N, Zhang Y
Frontiers in immunology 2021;12:796744
Frontiers in immunology 2021;12:796744
Activation of α7nAChR Protects Against Gastric Inflammation and Dysmotility in Parkinson's Disease Rats.
Zhou L, Zheng LF, Zhang XL, Wang ZY, Yao YS, Xiu XL, Liu CZ, Zhang Y, Feng XY, Zhu JX
Frontiers in pharmacology 2021;12:793374
Frontiers in pharmacology 2021;12:793374
Berberine Improves Irinotecan-Induced Intestinal Mucositis Without Impairing the Anti-colorectal Cancer Efficacy of Irinotecan by Inhibiting Bacterial β-glucuronidase.
Yue B, Gao R, Lv C, Yu Z, Wang H, Geng X, Wang Z, Dou W
Frontiers in pharmacology 2021;12:774560
Frontiers in pharmacology 2021;12:774560
Construction and Analysis of Immune Infiltration-Related ceRNA Network for Kidney Stones.
Xia Y, Zhou X, Ye Z, Yu W, Ning J, Ruan Y, Yuan R, Lin F, Ye P, Zheng D, Rao T, Cheng F
Frontiers in genetics 2021;12:774155
Frontiers in genetics 2021;12:774155
Claudin-5 Affects Endothelial Autophagy in Response to Early Hypoxia.
Yu P, Li Y, Zhong G, Li W, Chen B, Zhang J
Frontiers in physiology 2021;12:737474
Frontiers in physiology 2021;12:737474
Resveratrol Alleviates Levodopa-Induced Dyskinesia in Rats.
Zheng CQ, Fan HX, Li XX, Li JJ, Sheng S, Zhang F
Frontiers in immunology 2021;12:683577
Frontiers in immunology 2021;12:683577
Ligustrazine Alleviate Acute Lung Injury Through Suppressing Pyroptosis and Apoptosis of Alveolar Macrophages.
Jiang R, Xu J, Zhang Y, Zhu X, Liu J, Tan Y
Frontiers in pharmacology 2021;12:680512
Frontiers in pharmacology 2021;12:680512
Antioxidant activity of mesenchymal stem cell-derived extracellular vesicles restores hippocampal neurons following seizure damage.
Luo Q, Xian P, Wang T, Wu S, Sun T, Wang W, Wang B, Yang H, Yang Y, Wang H, Liu W, Long Q
Theranostics 2021;11(12):5986-6005
Theranostics 2021;11(12):5986-6005
Pseudomonas aeruginosa PcrV Enhances the Nitric Oxide-Mediated Tumoricidal Activity of Tumor-Associated Macrophages via a TLR4/PI3K/AKT/mTOR-Glycolysis-Nitric Oxide Circuit.
Yu H, Bai Y, Qiu J, He X, Xiong J, Dai Q, Wang X, Li Y, Sheng H, Xin R, Jiang L, Li Q, Li D, Zhang H, Zhang L, Chen Q, Peng J, Hu X, Zhang K
Frontiers in oncology 2021;11:736882
Frontiers in oncology 2021;11:736882
Colon-Targeted Adhesive Hydrogel Microsphere for Regulation of Gut Immunity and Flora.
Liu H, Cai Z, Wang F, Hong L, Deng L, Zhong J, Wang Z, Cui W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 Sep;8(18):e2101619
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 Sep;8(18):e2101619
The spatial form periosteal-bone complex promotes bone regeneration by coordinating macrophage polarization and osteogenic-angiogenic events.
Zhao C, Qiu P, Li M, Liang K, Tang Z, Chen P, Zhang J, Fan S, Lin X
Materials today. Bio 2021 Sep;12:100142
Materials today. Bio 2021 Sep;12:100142
Injectable shear-thinning polylysine hydrogels for localized immunotherapy of gastric cancer through repolarization of tumor-associated macrophages.
Yang Y, Yang Y, Chen M, Chen J, Wang J, Ma Y, Qian H
Biomaterials science 2021 Sep 28;9(19):6597-6608
Biomaterials science 2021 Sep 28;9(19):6597-6608
Chemical structure and anti-inflammatory activity of a branched polysaccharide isolated from Phellinus baumii.
Sun Y, Huo J, Zhong S, Zhu J, Li Y, Li X
Carbohydrate polymers 2021 Sep 15;268:118214
Carbohydrate polymers 2021 Sep 15;268:118214
Regulatory T cells protect against brain damage by alleviating inflammatory response in neuromyelitis optica spectrum disorder.
Ma X, Qin C, Chen M, Yu HH, Chu YH, Chen TJ, Bosco DB, Wu LJ, Bu BT, Wang W, Tian DS
Journal of neuroinflammation 2021 Sep 15;18(1):201
Journal of neuroinflammation 2021 Sep 15;18(1):201
Formosanin C attenuates lipopolysaccharide-induced inflammation through nuclear factor-κB inhibition in macrophages.
Yin L, Shi C, Zhang Z, Wang W, Li M
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2021 Sep 1;25(5):395-401
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2021 Sep 1;25(5):395-401
CLEC5A knockdown protects against cardiac dysfunction after myocardial infarction by suppressing macrophage polarization, NLRP3 inflammasome activation, and pyroptosis.
Wang X, Hu Y, Wang Y, Shen D, Tao G
Biochemistry and cell biology = Biochimie et biologie cellulaire 2021 Oct;99(5):655-665
Biochemistry and cell biology = Biochimie et biologie cellulaire 2021 Oct;99(5):655-665
Ameliorative effects of miR-423-5p against polarization of microglial cells of the M1 phenotype by targeting a NLRP3 inflammasome signaling pathway.
Cheng J, Hao J, Jiang X, Ji J, Wu T, Chen X, Zhang F
International immunopharmacology 2021 Oct;99:108006
International immunopharmacology 2021 Oct;99:108006
Avicularin suppresses cartilage extracellular matrix degradation and inflammation via TRAF6/MAPK activation.
Zou ZL, Sun MH, Yin WF, Yang L, Kong LY
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Oct;91:153657
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Oct;91:153657
Carbon Monoxide-Releasing Molecule-3 Regulates the Polarization of Lipopolysaccharide-Induced Macrophages.
Liu T, Han Q, Pan Y, Li J, Song H
Inflammation 2021 Oct;44(5):1737-1749
Inflammation 2021 Oct;44(5):1737-1749
Pharmacological Activation of RXR-α Promotes Hematoma Absorption via a PPAR-γ-dependent Pathway After Intracerebral Hemorrhage.
Xu C, Chen H, Zhou S, Sun C, Xia X, Peng Y, Zhuang J, Fu X, Zeng H, Zhou H, Cao Y, Yu Q, Li Y, Hu L, Zhou G, Yan F, Chen G, Li J
Neuroscience bulletin 2021 Oct;37(10):1412-1426
Neuroscience bulletin 2021 Oct;37(10):1412-1426
PARP14 inhibits microglial activation via LPAR5 to promote post-stroke functional recovery.
Tang Y, Liu J, Wang Y, Yang L, Han B, Zhang Y, Bai Y, Shen L, Li M, Jiang T, Ye Q, Yu X, Huang R, Zhang Z, Xu Y, Yao H
Autophagy 2021 Oct;17(10):2905-2922
Autophagy 2021 Oct;17(10):2905-2922
Rapid and effective treatment of traumatic spinal cord injury using stem cell derived exosomes.
Mu J, Wu J, Cao J, Ma T, Li L, Feng S, Gao J
Asian journal of pharmaceutical sciences 2021 Nov;16(6):806-815
Asian journal of pharmaceutical sciences 2021 Nov;16(6):806-815
Isoliquiritigenin alleviates LPS/ D-GalN-induced acute liver failure by activating the PGC-1α/ Nrf2 pathway to reduce oxidative stress and inflammatory response.
Wang L, Wang X, Kong L, Wang S, Huang K, Wu J, Wang C, Sun H, Liu K, Meng Q
International immunopharmacology 2021 Nov;100:108159
International immunopharmacology 2021 Nov;100:108159
Glial cell line-derived neurotrophic factor ameliorates dextran sulfate sodium-induced colitis in mice via a macrophage-mediated pathway.
Zeng J, Yu H, Gan HT
International immunopharmacology 2021 Nov;100:108143
International immunopharmacology 2021 Nov;100:108143
Discovery of Phenolic Glycoside from Hyssopus cuspidatus Attenuates LPS-Induced Inflammatory Responses by Inhibition of iNOS and COX-2 Expression through Suppression of NF-κB Activation.
Liu X, Su J, Wang G, Zheng L, Wang G, Sun Y, Bao Y, Wang S, Huang Y
International journal of molecular sciences 2021 Nov 9;22(22)
International journal of molecular sciences 2021 Nov 9;22(22)
Vagus nerve stimulation mediates microglia M1/2 polarization via inhibition of TLR4 pathway after ischemic stroke.
Zhang L, Liu Y, Wang S, Long L, Zang Q, Ma J, Yu L, Jia G
Biochemical and biophysical research communications 2021 Nov 5;577:71-79
Biochemical and biophysical research communications 2021 Nov 5;577:71-79
Photobiomodulation inhibits the activation of neurotoxic microglia and astrocytes by inhibiting Lcn2/JAK2-STAT3 crosstalk after spinal cord injury in male rats.
Wang X, Li X, Zuo X, Liang Z, Ding T, Li K, Ma Y, Li P, Zhu Z, Ju C, Zhang Z, Song Z, Quan H, Zhang J, Hu X, Wang Z
Journal of neuroinflammation 2021 Nov 5;18(1):256
Journal of neuroinflammation 2021 Nov 5;18(1):256
Sesquiterpene Lactones from Sigesbeckia glabrescens Possessing Potent Anti-inflammatory Activity by Directly Binding to IKKα/β.
Gao X, Shen X, Zheng Y, Yang L, Zhang X, Hu G, Jia J, Wang A
Journal of natural products 2021 Nov 26;84(11):2808-2821
Journal of natural products 2021 Nov 26;84(11):2808-2821
The Protective Role of Yin-Yang 1 in Cardiac Injury and Remodeling After Myocardial Infarction.
Huang Y, Li L, Chen H, Liao Q, Yang X, Yang D, Xia X, Wang H, Wang WE, Chen L, Zeng C
Journal of the American Heart Association 2021 Nov 2;10(21):e021895
Journal of the American Heart Association 2021 Nov 2;10(21):e021895
Decreased nitric oxide content mediated by asymmetrical dimethylarginine and protein l-arginine methyltransferase 3 in macrophages induces trophoblast apoptosis: a potential cause of recurrent miscarriage.
Hao F, Tang LC, Sun JX, Li WX, Zhao Y, Xu XH, Jin LP
Human reproduction (Oxford, England) 2021 Nov 18;36(12):3049-3061
Human reproduction (Oxford, England) 2021 Nov 18;36(12):3049-3061
Tetramethylpyrazine Protects Blood-Spinal Cord Barrier Integrity by Modulating Microglia Polarization Through Activation of STAT3/SOCS3 and Inhibition of NF-кB Signaling Pathways in Experimental Autoimmune Encephalomyelitis Mice.
Zhang L, Lu X, Gong L, Cui L, Zhang H, Zhao W, Jiang P, Hou G, Hou Y
Cellular and molecular neurobiology 2021 May;41(4):717-731
Cellular and molecular neurobiology 2021 May;41(4):717-731
Lipoxin A4 regulates microglial M1/M2 polarization after cerebral ischemia-reperfusion injury via the Notch signaling pathway.
Li QQ, Ding DH, Wang XY, Sun YY, Wu J
Experimental neurology 2021 May;339:113645
Experimental neurology 2021 May;339:113645
Protective effect of recombinant Lactobacillus plantarum against H(2)O(2)-induced oxidative stress in HUVEC cells.
Wang G, Hao M, Liu Q, Jiang Y, Huang H, Yang G, Wang C
Journal of Zhejiang University. Science. B 2021 May 15;22(5):348-365
Journal of Zhejiang University. Science. B 2021 May 15;22(5):348-365
Cardamonin protects nucleus pulposus cells against IL-1β-induced inflammation and catabolism via Nrf2/NF-κB axis.
Xie C, Ma H, Shi Y, Li J, Wu H, Wang B, Shao Z, Huang C, Chen J, Sun L, Zhou Y, Tian N, Wu Y, Gao W, Wu A, Wang X, Zhang X
Food & function 2021 Mar 21;12(6):2703-2714
Food & function 2021 Mar 21;12(6):2703-2714
CSF1/CSF1R-mediated Crosstalk Between Choroidal Vascular Endothelial Cells and Macrophages Promotes Choroidal Neovascularization.
Zhou Y, Zeng J, Tu Y, Li L, Du S, Zhu L, Cang X, Lu J, Zhu M, Liu X
Investigative ophthalmology & visual science 2021 Mar 1;62(3):37
Investigative ophthalmology & visual science 2021 Mar 1;62(3):37
Loganin alleviates sepsis-induced acute lung injury by regulating macrophage polarization and inhibiting NLRP3 inflammasome activation.
Zhang J, Wang C, Wang H, Li X, Xu J, Yu K
International immunopharmacology 2021 Jun;95:107529
International immunopharmacology 2021 Jun;95:107529
IL-1β pre-stimulation enhances the therapeutic effects of endometrial regenerative cells on experimental colitis.
Yu D, Zhao Y, Wang H, Kong D, Jin W, Hu Y, Qin Y, Zhang B, Li X, Hao J, Li G, Wang H
Stem cell research & therapy 2021 Jun 5;12(1):324
Stem cell research & therapy 2021 Jun 5;12(1):324
Dietary Ursolic Acid Prevents Alcohol-Induced Liver Injury via Gut-Liver Axis Homeostasis Modulation: The Key Role of Microbiome Manipulation.
Yan X, Ren X, Liu X, Wang Y, Ma J, Song R, Wang X, Dong Y, Fan Q, Wei J, Yu A, She G
Journal of agricultural and food chemistry 2021 Jun 30;69(25):7074-7083
Journal of agricultural and food chemistry 2021 Jun 30;69(25):7074-7083
Thymosin β4 reverses phenotypic polarization of glial cells and cognitive impairment via negative regulation of NF-κB signaling axis in APP/PS1 mice.
Wang M, Feng LR, Li ZL, Ma KG, Chang KW, Chen XL, Yang PB, Ji SF, Ma YB, Han H, Ruganzua JB, Yang WN, Qian YH
Journal of neuroinflammation 2021 Jun 28;18(1):146
Journal of neuroinflammation 2021 Jun 28;18(1):146
X-ray Structure-Guided Discovery of a Potent, Orally Bioavailable, Dual Human Indoleamine/Tryptophan 2,3-Dioxygenase (hIDO/hTDO) Inhibitor That Shows Activity in a Mouse Model of Parkinson's Disease.
Ning XL, Li YZ, Huo C, Deng J, Gao C, Zhu KR, Wang M, Wu YX, Yu JL, Ren YL, Luo ZY, Li G, Chen Y, Wang SY, Peng C, Yang LL, Wang ZY, Wu Y, Qian S, Li GB
Journal of medicinal chemistry 2021 Jun 24;64(12):8303-8332
Journal of medicinal chemistry 2021 Jun 24;64(12):8303-8332
Protective effect of scorpion venom heat-resistant synthetic peptide against PM(2.5)-induced microglial polarization via TLR4-mediated autophagy activating PI3K/AKT/NF-κB signaling pathway.
Xu X, Xu H, Ren F, Huang L, Xu J, Li F
Journal of neuroimmunology 2021 Jun 15;355:577567
Journal of neuroimmunology 2021 Jun 15;355:577567
A systematic CRISPR screen reveals an IL-20/IL20RA-mediated immune crosstalk to prevent the ovarian cancer metastasis.
Li J, Qin X, Shi J, Wang X, Li T, Xu M, Chen X, Zhao Y, Han J, Piao Y, Zhang W, Qu P, Wang L, Xiang R, Shi Y
eLife 2021 Jun 11;10
eLife 2021 Jun 11;10
Wireless Localized Electrical Stimulation Generated by an Ultrasound-Driven Piezoelectric Discharge Regulates Proinflammatory Macrophage Polarization.
Kong Y, Liu F, Ma B, Duan J, Yuan W, Sang Y, Han L, Wang S, Liu H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 Jul;8(13):2100962
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 Jul;8(13):2100962
Effects of medicine food Fructus Gardeniae on liver and kidney functions after oral administration to rats for 12 weeks.
Li C, Gao X, Gao X, Lv J, Bian X, Lv J, Sun J, Luo G, Zhang H
Journal of food biochemistry 2021 Jul;45(7):e13752
Journal of food biochemistry 2021 Jul;45(7):e13752
α-Cyperone (CYP) down-regulates NF-κB and MAPKs signaling, attenuating inflammation and extracellular matrix degradation in chondrocytes, to ameliorate osteoarthritis in mice.
Zhang H, Li S, Lu J, Jin J, Zhu G, Wang L, Yan Y, He L, Wang B, Wang X, Yu H
Aging 2021 Jul 8;13(13):17690-17706
Aging 2021 Jul 8;13(13):17690-17706
Anti-inflammatory and tight junction protective activity of the herbal preparation STW 5-II on mouse intestinal organoids.
Elbadawi M, Ammar RM, Aziz-Kalbhenn H, Rabini S, Klauck SM, Dawood M, Saeed MEM, Kampf CJ, Efferth T
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Jul 15;88:153589
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Jul 15;88:153589
Impaired autophagy in microglia aggravates dopaminergic neurodegeneration by regulating NLRP3 inflammasome activation in experimental models of Parkinson's disease.
Qin Y, Qiu J, Wang P, Liu J, Zhao Y, Jiang F, Lou H
Brain, behavior, and immunity 2021 Jan;91:324-338
Brain, behavior, and immunity 2021 Jan;91:324-338
Physcion 8-O-β-glucopyranoside ameliorates liver fibrosis through inflammation inhibition by regulating SIRT3-mediated NF-κB P65 nuclear expression.
Chen C, Gu J, Wang J, Wu Y, Yang A, Chen T, Zhou T, Liu Z
International immunopharmacology 2021 Jan;90:107206
International immunopharmacology 2021 Jan;90:107206
Echinacea polysaccharide attenuates lipopolysaccharide‑induced acute kidney injury via inhibiting inflammation, oxidative stress and the MAPK signaling pathway.
Shi Q, Lang W, Wang S, Li G, Bai X, Yan X, Zhang H
International journal of molecular medicine 2021 Jan;47(1):243-255
International journal of molecular medicine 2021 Jan;47(1):243-255
Myricetin ameliorates sepsis-associated acute lung injury in a murine sepsis model.
Xu H, Qi Q, Yan X
Naunyn-Schmiedeberg's archives of pharmacology 2021 Jan;394(1):165-175
Naunyn-Schmiedeberg's archives of pharmacology 2021 Jan;394(1):165-175
Sodium alginate/collagen hydrogel loaded with human umbilical cord mesenchymal stem cells promotes wound healing and skin remodeling.
Zhang Z, Li Z, Li Y, Wang Y, Yao M, Zhang K, Chen Z, Yue H, Shi J, Guan F, Ma S
Cell and tissue research 2021 Feb;383(2):809-821
Cell and tissue research 2021 Feb;383(2):809-821
Rea regulates microglial polarization and attenuates neuronal apoptosis via inhibition of the NF-κB and MAPK signalings for spinal cord injury repair.
Xiao S, Wang C, Yang Q, Xu H, Lu J, Xu K
Journal of cellular and molecular medicine 2021 Feb;25(3):1371-1382
Journal of cellular and molecular medicine 2021 Feb;25(3):1371-1382
Critical roles of sphingosine kinase 1 in the regulation of neuroinflammation and neuronal injury after spinal cord injury.
Wang C, Xu T, Lachance BB, Zhong X, Shen G, Xu T, Tang C, Jia X
Journal of neuroinflammation 2021 Feb 18;18(1):50
Journal of neuroinflammation 2021 Feb 18;18(1):50
Phosphorylated nuclear factor erythroid 2-related factor 2 promotes the secretion of C-C motif chemokine ligand 2 and the recruitment of M2 macrophages.
Huang Z, Li X, Zhou T, Jiang Y, Shi JH
Annals of translational medicine 2021 Dec;9(23):1719
Annals of translational medicine 2021 Dec;9(23):1719
Schizandrin A ameliorates cognitive functions via modulating microglial polarisation in Alzheimer's disease mice.
Wang Q, Liu L, Guan H, Zhou Y, Li Q
Pharmaceutical biology 2021 Dec;59(1):860-867
Pharmaceutical biology 2021 Dec;59(1):860-867
CircPrkcsh, a circular RNA, contributes to the polarization of microglia towards the M1 phenotype induced by spinal cord injury and acts via the JNK/p38 MAPK pathway.
Li X, Kang J, Lv H, Liu R, Chen J, Zhang Y, Zhang Y, Yu G, Zhang X, Ning B
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Dec;35(12):e22014
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Dec;35(12):e22014
PLXNA2 knockdown promotes M2 microglia polarization through mTOR/STAT3 signaling to improve functional recovery in rats after cerebral ischemia/reperfusion injury.
Li S, Hua X, Zheng M, Wu J, Ma Z, Xing X, Ma J, Zhang J, Shan C, Xu J
Experimental neurology 2021 Dec;346:113854
Experimental neurology 2021 Dec;346:113854
Diterpenoid alkaloids from Delphinium forrestii var. viride and their anti-inflammation activity.
Song Z, Gao C, Jiang Q, Xu J, Xiong L, Liu K, Sun D, Li H, Chen L
Phytochemistry 2021 Dec;192:112971
Phytochemistry 2021 Dec;192:112971
The glycolysis inhibitor 2-deoxyglucose ameliorates adjuvant-induced arthritis by regulating macrophage polarization in an AMPK-dependent manner.
Cai W, Cheng J, Zong S, Yu Y, Wang Y, Song Y, He R, Yuan S, Chen T, Hu M, Pan Y, Ma R, Liu H, Wei F
Molecular immunology 2021 Dec;140:186-195
Molecular immunology 2021 Dec;140:186-195
Inhibition of Dectin-1 Ameliorates Neuroinflammation by Regulating Microglia/Macrophage Phenotype After Intracerebral Hemorrhage in Mice.
Fu X, Zeng H, Zhao J, Zhou G, Zhou H, Zhuang J, Xu C, Li J, Peng Y, Cao Y, Li Y, Chen H, Wang L, Yan F, Chen G
Translational stroke research 2021 Dec;12(6):1018-1034
Translational stroke research 2021 Dec;12(6):1018-1034
Acetylcholinesterase inhibition with Pyridostigmine attenuates hypertension and neuroinflammation in the paraventricular nucleus in rat model for Preeclampsia.
Issotina Zibrila A, Li Y, Wang Z, Zhao G, Liu H, Leng J, Ahasan Ali M, Ampofo Osei J, Kang YM, Liu J
International immunopharmacology 2021 Dec;101(Pt B):108365
International immunopharmacology 2021 Dec;101(Pt B):108365
The Promising Role of Chitosan-Poloxamer 188 Nanocrystals in Improving Diosmin Dissolution and Therapeutic Efficacy against Ferrous Sulfate-Induced Hepatic Injury in Rats.
Lotfy NS, Borg TM, Mohamed EA
Pharmaceutics 2021 Dec 5;13(12)
Pharmaceutics 2021 Dec 5;13(12)
Probiotic Bacillus cereus Alleviates Dextran Sulfate Sodium-Induced Colitis in Mice through Improvement of the Intestinal Barrier Function, Anti-Inflammation, and Gut Microbiota Modulation.
Sheng K, Xu Y, Kong X, Wang J, Zha X, Wang Y
Journal of agricultural and food chemistry 2021 Dec 15;69(49):14810-14823
Journal of agricultural and food chemistry 2021 Dec 15;69(49):14810-14823
Synergistic anti-inflammatory activity of apigenin and curcumin co-encapsulated in caseins assessed with lipopolysaccharide-stimulated RAW 264.7 macrophages.
Hong S, Dia VP, Zhong Q
International journal of biological macromolecules 2021 Dec 15;193(Pt A):702-712
International journal of biological macromolecules 2021 Dec 15;193(Pt A):702-712
FNDC5 induces M2 macrophage polarization and promotes hepatocellular carcinoma cell growth by affecting the PPARγ/NF-κB/NLRP3 pathway.
Liu H, Wang M, Jin Z, Sun D, Zhu T, Liu X, Tan X, Shi G
Biochemical and biophysical research communications 2021 Dec 10;582:77-85
Biochemical and biophysical research communications 2021 Dec 10;582:77-85
MicroRNA-155-5p promotes neuroinflammation and central sensitization via inhibiting SIRT1 in a nitroglycerin-induced chronic migraine mouse model.
Wen Q, Wang Y, Pan Q, Tian R, Zhang D, Qin G, Zhou J, Chen L
Journal of neuroinflammation 2021 Dec 10;18(1):287
Journal of neuroinflammation 2021 Dec 10;18(1):287
The role of adenosine A(1) receptor in the peripheral tramadol's effect in the temporomandibular joint of rats.
Abdalla HB, Napimoga MH, de Macedo Maganin AG, Lopes AH, Cunha TM, Gill HS, Clemente-Napimoga JT
International immunopharmacology 2021 Aug;97:107680
International immunopharmacology 2021 Aug;97:107680
The expression profile and bioinformatics analysis of microRNAs in human bronchial epithelial cells treated by beryllium sulfate.
Yi S, Liu YP, Li XY, Yuan XY, Wang Y, Cai Y, Lei YD, Huang L, Zhang ZH
Journal of applied toxicology : JAT 2021 Aug;41(8):1275-1285
Journal of applied toxicology : JAT 2021 Aug;41(8):1275-1285
Aiduqing formula inhibits breast cancer metastasis by suppressing TAM/CXCL1-induced Treg differentiation and infiltration.
Li J, Wang S, Wang N, Zheng Y, Yang B, Wang X, Zhang J, Pan B, Wang Z
Cell communication and signaling : CCS 2021 Aug 30;19(1):89
Cell communication and signaling : CCS 2021 Aug 30;19(1):89
Nitric oxide mediates disruption of human placental trophoblast invasion induced by perfluorobutane sulfonate.
Du Y, Cai Z, Zhang H, Liang W, Wang H, Man Q, Wang W
Environmental pollution (Barking, Essex : 1987) 2021 Aug 15;283:117137
Environmental pollution (Barking, Essex : 1987) 2021 Aug 15;283:117137
SCARF1 promotes M2 polarization of Kupffer cells via calcium-dependent PI3K-AKT-STAT3 signalling to improve liver transplantation.
Xu XS, Feng ZH, Cao D, Wu H, Wang MH, Li JZ, Gong JP
Cell proliferation 2021 Apr;54(4):e13022
Cell proliferation 2021 Apr;54(4):e13022
Morroniside protects OLN-93 cells against H(2)O(2)-induced injury through the PI3K/Akt pathway-mediated antioxidative stress and antiapoptotic activities.
Li F, Song X, Xu J, Shi Y, Hu R, Ren Z, Qi Q, Lü H, Cheng X, Hu J
Cell cycle (Georgetown, Tex.) 2021 Apr;20(7):661-675
Cell cycle (Georgetown, Tex.) 2021 Apr;20(7):661-675
Targeting macrophage liver X receptors by hydrogel-encapsulated T0901317 reduces atherosclerosis without effect on hepatic lipogenesis.
Ma C, Feng K, Yang X, Yang Z, Wang Z, Shang Y, Fan G, Liu L, Yang S, Li X, Han J, Duan Y, Chen Y
British journal of pharmacology 2021 Apr;178(7):1620-1638
British journal of pharmacology 2021 Apr;178(7):1620-1638
Angiotensin II type 1 receptor is involved in flow-induced vasomotor responses of isolated middle cerebral arteries: role of oxidative stress.
Jukic I, Mihaljevic Z, Matic A, Mihalj M, Kozina N, Selthofer-Relatic K, Mihaljevic D, Koller A, Tartaro Bujak I, Drenjancevic I
American journal of physiology. Heart and circulatory physiology 2021 Apr 1;320(4):H1609-H1624
American journal of physiology. Heart and circulatory physiology 2021 Apr 1;320(4):H1609-H1624
Deliver Anti-inflammatory Drug Baicalein to Macrophages by Using a Crystallization Strategy.
Zhang J, Teng C, Li C, He W
Frontiers in chemistry 2020;8:787
Frontiers in chemistry 2020;8:787
Injectable Gelatin Hydrogel Suppresses Inflammation and Enhances Functional Recovery in a Mouse Model of Intracerebral Hemorrhage.
Xu J, Duan Z, Qi X, Ou Y, Guo X, Zi L, Wei Y, Liu H, Ma L, Li H, You C, Tian M
Frontiers in bioengineering and biotechnology 2020;8:785
Frontiers in bioengineering and biotechnology 2020;8:785
Koumine Alleviates Lipopolysaccharide-Induced Intestinal Barrier Dysfunction in IPEC-J2 Cells by Regulating Nrf2/NF-κB Pathway.
Wu J, Yang CL, Sha YK, Wu Y, Liu ZY, Yuan ZH, Sun ZL
The American journal of Chinese medicine 2020;48(1):127-142
The American journal of Chinese medicine 2020;48(1):127-142
Ovariectomy Induces Microglial Cell Activation and Inflammatory Response in Rat Prefrontal Cortices to Accelerate the Chronic Unpredictable Stress-Mediated Anxiety and Depression.
Ge F, Yang H, Lu W, Shi H, Chen Q, Luo Y, Liu L, Yan J
BioMed research international 2020;2020:3609758
BioMed research international 2020;2020:3609758
Emodin Alleviates Hydrogen Peroxide-Induced Inflammation and Oxidative Stress via Mitochondrial Dysfunction by Inhibiting the PI3K/mTOR/GSK3β Pathway in Neuroblastoma SH-SY5Y Cells.
Li R, Liu W, Ou L, Gao F, Li M, Wang L, Wei P, Miao F
BioMed research international 2020;2020:1562915
BioMed research international 2020;2020:1562915
Intranasal Delivery of Bone Marrow Stromal Cells Preconditioned with Fasudil to Treat a Mouse Model of Parkinson's Disease.
Tang Y, Han L, Bai X, Liang X, Zhao J, Huang F, Wang J
Neuropsychiatric disease and treatment 2020;16:249-262
Neuropsychiatric disease and treatment 2020;16:249-262
La(2)O(3) Nanoparticles Induce Reproductive Toxicity Mediated by the Nrf-2/ARE Signaling Pathway in Kunming Mice.
Yuan L, Li Q, Bai D, Shang X, Hu F, Chen Z, An T, Chen Y, Zhang X
International journal of nanomedicine 2020;15:3415-3431
International journal of nanomedicine 2020;15:3415-3431
Hypothermia-Induced Ubiquitination of Voltage-Dependent Anion Channel 3 Protects BV2 Microglia Cells From Cytotoxicity Following Oxygen-Glucose Deprivation/Recovery.
Zhao S, Xiao P, Cui H, Gong P, Lin C, Chen F, Tang Z
Frontiers in molecular neuroscience 2020;13:100
Frontiers in molecular neuroscience 2020;13:100
Salvianolic Acid A Has Anti-Osteoarthritis Effect In Vitro and In Vivo.
Wu Y, Wang Z, Lin Z, Fu X, Zhan J, Yu K
Frontiers in pharmacology 2020;11:682
Frontiers in pharmacology 2020;11:682
Tetramethylpyrazine Ameliorates Lipopolysaccharide-Induced Sepsis in Rats via Protecting Blood-Brain Barrier, Impairing Inflammation and Nitrous Oxide Systems.
Huang ZS, Xie DQ, Xu LJ, Huang CS, Zheng M, Chen YJ, Cao Y
Frontiers in pharmacology 2020;11:562084
Frontiers in pharmacology 2020;11:562084
CCR4 Antagonist (C021) Administration Diminishes Hypersensitivity and Enhances the Analgesic Potency of Morphine and Buprenorphine in a Mouse Model of Neuropathic Pain.
Bogacka J, Ciapała K, Pawlik K, Kwiatkowski K, Dobrogowski J, Przeklasa-Muszynska A, Mika J
Frontiers in immunology 2020;11:1241
Frontiers in immunology 2020;11:1241
Formononetin attenuates atherosclerosis via regulating interaction between KLF4 and SRA in apoE(-/-) mice.
Ma C, Xia R, Yang S, Liu L, Zhang J, Feng K, Shang Y, Qu J, Li L, Chen N, Xu S, Zhang W, Mao J, Han J, Chen Y, Yang X, Duan Y, Fan G
Theranostics 2020;10(3):1090-1106
Theranostics 2020;10(3):1090-1106
Bifunctional supramolecular nanofiber inhibits atherosclerosis by enhancing plaque stability and anti-inflammation in apoE(-/-) mice.
Shang Y, Ma C, Zhang J, Wang Z, Ren C, Luo X, Peng R, Liu J, Mao J, Shi Y, Fan G
Theranostics 2020;10(22):10231-10244
Theranostics 2020;10(22):10231-10244
Mesenchymal stem cell-loaded thermosensitive hydroxypropyl chitin hydrogel combined with a three-dimensional-printed poly(ε-caprolactone) /nano-hydroxyapatite scaffold to repair bone defects via osteogenesis, angiogenesis and immunomodulation.
Ji X, Yuan X, Ma L, Bi B, Zhu H, Lei Z, Liu W, Pu H, Jiang J, Jiang X, Zhang Y, Xiao J
Theranostics 2020;10(2):725-740
Theranostics 2020;10(2):725-740
Herb-sourced emodin inhibits angiogenesis of breast cancer by targeting VEGFA transcription.
Zou G, Zhang X, Wang L, Li X, Xie T, Zhao J, Yan J, Wang L, Ye H, Jiao S, Xiang R, Shi Y
Theranostics 2020;10(15):6839-6853
Theranostics 2020;10(15):6839-6853
Geraniol-mediated osteoarthritis improvement by down-regulating PI3K/Akt/NF-κB and MAPK signals: In vivo and in vitro studies.
Wu Y, Wang Z, Fu X, Lin Z, Yu K
International immunopharmacology 2020 Sep;86:106713
International immunopharmacology 2020 Sep;86:106713
Fucoidan inhibits tooth movement by promoting restorative macrophage polarization through the STAT3 pathway.
Zhang S, Zhang H, Jin Z, Wang S, Wang Y, Zhu L, Sun W, Yan B
Journal of cellular physiology 2020 Sep;235(9):5938-5950
Journal of cellular physiology 2020 Sep;235(9):5938-5950
Inhibition of miR-181a-5p reduces astrocyte and microglia activation and oxidative stress by activating SIRT1 in immature rats with epilepsy.
Kong H, Wang H, Zhuo Z, Li Z, Tian P, Wu J, Liu J, Chen Z, Zhang J, Luo Q
Laboratory investigation; a journal of technical methods and pathology 2020 Sep;100(9):1223-1237
Laboratory investigation; a journal of technical methods and pathology 2020 Sep;100(9):1223-1237
MG53 Protects hUC-MSCs against Inflammatory Damage and Synergistically Enhances Their Efficacy in Neuroinflammation Injured Brain through Inhibiting NLRP3/Caspase-1/IL-1β Axis.
Ma S, Wang Y, Zhou X, Li Z, Zhang Z, Wang Y, Huang T, Zhang Y, Shi J, Guan F
ACS chemical neuroscience 2020 Sep 2;11(17):2590-2601
ACS chemical neuroscience 2020 Sep 2;11(17):2590-2601
Arachidonic Acid Metabolites of CYP450 Enzymes and HIF-1α Modulate Endothelium-Dependent Vasorelaxation in Sprague-Dawley Rats under Acute and Intermittent Hyperbaric Oxygenation.
Mihaljević Z, Matić A, Stupin A, Frkanec R, Tavčar B, Kelava V, Tartaro Bujak I, Kolobarić N, Kibel A, Drenjančević I
International journal of molecular sciences 2020 Sep 1;21(17)
International journal of molecular sciences 2020 Sep 1;21(17)
Peripheral soluble epoxide hydrolase inhibition reduces hypernociception and inflammation in albumin-induced arthritis in temporomandibular joint of rats.
Teixeira JM, Abdalla HB, Basting RT, Hammock BD, Napimoga MH, Clemente-Napimoga JT
International immunopharmacology 2020 Oct;87:106841
International immunopharmacology 2020 Oct;87:106841
Anti-arthritis effect of berberine associated with regulating energy metabolism of macrophages through AMPK/ HIF-1α pathway.
Yu Y, Cai W, Zhou J, Lu H, Wang Y, Song Y, He R, Pei F, Wang X, Zhang R, Liu H, Wei F
International immunopharmacology 2020 Oct;87:106830
International immunopharmacology 2020 Oct;87:106830
Increased expression levels of inflammatory cytokines and adhesion molecules in lipopolysaccharide‑induced acute inflammatory apoM‑/‑ mice.
Shi Y, Liu H, Liu H, Yu Y, Zhang J, Li Y, Luo G, Zhang X, Xu N
Molecular medicine reports 2020 Oct;22(4):3117-3126
Molecular medicine reports 2020 Oct;22(4):3117-3126
Protective effect of astaxanthin against La(2)O(3) nanoparticles induced neurotoxicity by activating PI3K/AKT/Nrf-2 signaling in mice.
Yuan L, Qu Y, Li Q, An T, Chen Z, Chen Y, Deng X, Bai D
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2020 Oct;144:111582
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2020 Oct;144:111582
(-)-Hydroxycitric Acid Alleviates Oleic Acid-Induced Steatosis, Oxidative Stress, and Inflammation in Primary Chicken Hepatocytes by Regulating AMP-Activated Protein Kinase-Mediated Reactive Oxygen Species Levels.
Li L, Chu X, Yao Y, Cao J, Li Q, Ma H
Journal of agricultural and food chemistry 2020 Oct 7;68(40):11229-11241
Journal of agricultural and food chemistry 2020 Oct 7;68(40):11229-11241
Ketogenic Diet Elicits Antitumor Properties through Inducing Oxidative Stress, Inhibiting MMP-9 Expression, and Rebalancing M1/M2 Tumor-Associated Macrophage Phenotype in a Mouse Model of Colon Cancer.
Zhang N, Liu C, Jin L, Zhang R, Wang T, Wang Q, Chen J, Yang F, Siebert HC, Zheng X
Journal of agricultural and food chemistry 2020 Oct 7;68(40):11182-11196
Journal of agricultural and food chemistry 2020 Oct 7;68(40):11182-11196
Distribution and polarization of microglia and macrophages at injured sites and the lumbar enlargement after spinal cord injury.
Nakajima H, Honjoh K, Watanabe S, Kubota A, Matsumine A
Neuroscience letters 2020 Oct 15;737:135152
Neuroscience letters 2020 Oct 15;737:135152
Protective effect of astaxanthin against SnS(2) nanoflowers induced testes toxicity by suppressing RIPK1-RIPK3-MLKL signaling in mice.
Yuan L, Liang P, Qu Y, An T, Wang J, Deng X, Bai L, Shen P, Bai D
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2020 Nov;145:111736
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2020 Nov;145:111736
Scoparone improves hepatic inflammation and autophagy in mice with nonalcoholic steatohepatitis by regulating the ROS/P38/Nrf2 axis and PI3K/AKT/mTOR pathway in macrophages.
Liu B, Deng X, Jiang Q, Li G, Zhang J, Zhang N, Xin S, Xu K
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109895
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109895
Honokiol inhibits carotid artery atherosclerotic plaque formation by suppressing inflammation and oxidative stress.
Liu Y, Cheng P, Wu AH
Aging 2020 May 4;12(9):8016-8028
Aging 2020 May 4;12(9):8016-8028
Stimulator of IFN genes mediates neuroinflammatory injury by suppressing AMPK signal in experimental subarachnoid hemorrhage.
Peng Y, Zhuang J, Ying G, Zeng H, Zhou H, Cao Y, Chen H, Xu C, Fu X, Xu H, Li J, Cao S, Chen J, Gu C, Yan F, Chen G
Journal of neuroinflammation 2020 May 25;17(1):165
Journal of neuroinflammation 2020 May 25;17(1):165
Oroxylin A inhibits carcinogen-induced skin tumorigenesis through inhibition of inflammation by regulating SHCBP1 in mice.
Huang H, Cai H, Zhang L, Hua Z, Shi J, Wei Y
International immunopharmacology 2020 Mar;80:106123
International immunopharmacology 2020 Mar;80:106123
A Comparison of Splenic Pathologic Change and Immune Function in HBV-Related Portal Hypertension and Chinese Budd-Chiari Syndrome Patients with Hypersplenism.
Li S, Huang N, Dang X, Li L, Li Z, Zhang C, Jiang A, Kong G, Ji F, Yang J, Li Z
Viral immunology 2020 Mar;33(2):112-121
Viral immunology 2020 Mar;33(2):112-121
XIAOPI formula inhibits the pre-metastatic niche formation in breast cancer via suppressing TAMs/CXCL1 signaling.
Zheng Y, Wang N, Wang S, Yang B, Situ H, Zhong L, Lin Y, Wang Z
Cell communication and signaling : CCS 2020 Mar 26;18(1):48
Cell communication and signaling : CCS 2020 Mar 26;18(1):48
The protective effect of hesperetin in osteoarthritis: an in vitro and in vivo study.
Lin Z, Fu C, Yan Z, Wu Y, Zhan J, Lou Z, Liao X, Pan J
Food & function 2020 Mar 26;11(3):2654-2666
Food & function 2020 Mar 26;11(3):2654-2666
TNF-α/HMGB1 inflammation signalling pathway regulates pyroptosis during liver failure and acute kidney injury.
Wang Y, Zhang H, Chen Q, Jiao F, Shi C, Pei M, Lv J, Zhang H, Wang L, Gong Z
Cell proliferation 2020 Jun;53(6):e12829
Cell proliferation 2020 Jun;53(6):e12829
AGK2 Alleviates Lipopolysaccharide Induced Neuroinflammation through Regulation of Mitogen-Activated Protein Kinase Phosphatase-1.
Jiao F, Wang Y, Zhang W, Zhang H, Chen Q, Wang L, Shi C, Gong Z
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2020 Jun;15(2):196-208
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2020 Jun;15(2):196-208
Beneficial Effects of Theta-Burst Transcranial Magnetic Stimulation on Stroke Injury via Improving Neuronal Microenvironment and Mitochondrial Integrity.
Zong X, Dong Y, Li Y, Yang L, Li Y, Yang B, Tucker L, Zhao N, Brann DW, Yan X, Hu S, Zhang Q
Translational stroke research 2020 Jun;11(3):450-467
Translational stroke research 2020 Jun;11(3):450-467
lncRNA PVT1 Promotes Tumorigenesis of Colorectal Cancer by Stabilizing miR-16-5p and Interacting with the VEGFA/VEGFR1/AKT Axis.
Wu H, Wei M, Jiang X, Tan J, Xu W, Fan X, Zhang R, Ding C, Zhao F, Shao X, Zhang Z, Shi R, Zhang W, Wu G
Molecular therapy. Nucleic acids 2020 Jun 5;20:438-450
Molecular therapy. Nucleic acids 2020 Jun 5;20:438-450
TSPO ligand Ro5-4864 modulates microglia/macrophages polarization after subarachnoid hemorrhage in mice.
Zhou J, Zhang X, Peng J, Xie Y, Du F, Guo K, Feng Y, Zhang L, Chen L, Jiang Y
Neuroscience letters 2020 Jun 11;729:134977
Neuroscience letters 2020 Jun 11;729:134977
Activation of PPAR-γ induces macrophage polarization and reduces neutrophil migration mediated by heme oxygenase 1.
Abdalla HB, Napimoga MH, Lopes AH, de Macedo Maganin AG, Cunha TM, Van Dyke TE, Clemente Napimoga JT
International immunopharmacology 2020 Jul;84:106565
International immunopharmacology 2020 Jul;84:106565
The protective effect of myricitrin in osteoarthritis: An in vitro and in vivo study.
Yan Z, Lin Z, Wu Y, Zhan J, Qi W, Lin J, Shen J, Xue X, Pan X
International immunopharmacology 2020 Jul;84:106511
International immunopharmacology 2020 Jul;84:106511
10-Hydroxydecanoic acid inhibits LPS-induced inflammation by targeting p53 in microglial cells.
You M, Miao Z, Sienkiewicz O, Jiang X, Zhao X, Hu F
International immunopharmacology 2020 Jul;84:106501
International immunopharmacology 2020 Jul;84:106501
Mechanism investigation on Bisphenol S-induced oxidative stress and inflammation in murine RAW264.7 cells: The role of NLRP3 inflammasome, TLR4, Nrf2 and MAPK.
Xie C, Ge M, Jin J, Xu H, Mao L, Geng S, Wu J, Zhu J, Li X, Zhong C
Journal of hazardous materials 2020 Jul 15;394:122549
Journal of hazardous materials 2020 Jul 15;394:122549
Karyopherin α 2 promotes proliferation, migration and invasion through activating NF-κB/p65 signaling pathways in melanoma cells.
Yang F, Li S, Cheng Y, Li J, Han X
Life sciences 2020 Jul 1;252:117611
Life sciences 2020 Jul 1;252:117611
Chicken thalamic injury induced by copper (II) or / and arsenite exposure involves oxidative stress and inflammation-induced apoptosis.
Wang D, Zong C, Cheng K
Ecotoxicology and environmental safety 2020 Jul 1;197:110554
Ecotoxicology and environmental safety 2020 Jul 1;197:110554
Antidepressant activity of ω-3 polyunsaturated fatty acids in ovariectomized rats: role of neuroinflammation and microglial polarization.
Wu B, Song Q, Zhang Y, Wang C, Yang M, Zhang J, Han W, Jiang P
Lipids in health and disease 2020 Jan 8;19(1):4
Lipids in health and disease 2020 Jan 8;19(1):4
TLR 7/8 agonist reverses oxaliplatin resistance in colorectal cancer via directing the myeloid-derived suppressor cells to tumoricidal M1-macrophages.
Liu Z, Xie Y, Xiong Y, Liu S, Qiu C, Zhu Z, Mao H, Yu M, Wang X
Cancer letters 2020 Jan 28;469:173-185
Cancer letters 2020 Jan 28;469:173-185
Biglycan regulates neuroinflammation by promoting M1 microglial activation in early brain injury after experimental subarachnoid hemorrhage.
Xie Y, Peng J, Pang J, Guo K, Zhang L, Yin S, Zhou J, Gu L, Tu T, Mu Q, Liao Y, Zhang X, Chen L, Jiang Y
Journal of neurochemistry 2020 Feb;152(3):368-380
Journal of neurochemistry 2020 Feb;152(3):368-380
MiRNA-192-5p attenuates airway remodeling and autophagy in asthma by targeting MMP-16 and ATG7.
Lou L, Tian M, Chang J, Li F, Zhang G
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Feb;122:109692
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Feb;122:109692
Silencing of PTX3 alleviates LPS-induced inflammatory pain by regulating TLR4/NF-κB signaling pathway in mice.
Qi S, Zhao F, Li Z, Liang F, Yu S
Bioscience reports 2020 Feb 28;40(2)
Bioscience reports 2020 Feb 28;40(2)
CT/NIRF dual-modal imaging tracking and therapeutic efficacy of transplanted mesenchymal stem cells labeled with Au nanoparticles in silica-induced pulmonary fibrosis.
Huang J, Huang J, Ning X, Luo W, Chen M, Wang Z, Zhang W, Zhang Z, Chao J
Journal of materials chemistry. B 2020 Feb 26;8(8):1713-1727
Journal of materials chemistry. B 2020 Feb 26;8(8):1713-1727
Syringin protects against colitis by ameliorating inflammation.
Zhang H, Gu H, Jia Q, Zhao Y, Li H, Shen S, Liu X, Wang G, Shi Q
Archives of biochemistry and biophysics 2020 Feb 15;680:108242
Archives of biochemistry and biophysics 2020 Feb 15;680:108242
Intravenously Infusing the Secretome of Adipose-Derived Mesenchymal Stem Cells Ameliorates Neuroinflammation and Neurological Functioning After Traumatic Brain Injury.
Xu C, Diao YF, Wang J, Liang J, Xu HH, Zhao ML, Zheng B, Luan Z, Wang JJ, Yang XP, Wei MG, Duan JH, Wang KQ, Chen C, Chen F, Ming D, Zhang S, Sun HT, Li XH
Stem cells and development 2020 Feb 15;29(4):222-234
Stem cells and development 2020 Feb 15;29(4):222-234
Maresin 1 mitigates concanavalin A-induced acute liver injury in mice by inhibiting ROS-mediated activation of NF-κB signaling.
Zhang P, Yin Y, Wang T, Li W, Li C, Zeng X, Yang W, Zhang R, Tang Y, Shi L, Li R, Tao K
Free radical biology & medicine 2020 Feb 1;147:23-36
Free radical biology & medicine 2020 Feb 1;147:23-36
Autotaxin stimulates LPA2 receptor in macrophages and exacerbates dextran sulfate sodium-induced acute colitis.
Wang Z, Shi W, Tian D, Qin H, Vallance BA, Yang H, Yu HB, Yu Q
Journal of molecular medicine (Berlin, Germany) 2020 Dec;98(12):1781-1794
Journal of molecular medicine (Berlin, Germany) 2020 Dec;98(12):1781-1794
Protective effect of hydroxysafflor yellow A on dopaminergic neurons against 6-hydroxydopamine, activating anti-apoptotic and anti-neuroinflammatory pathways.
Yang X, Li Y, Chen L, Xu M, Wu J, Zhang P, Nel D, Sun B
Pharmaceutical biology 2020 Dec;58(1):686-694
Pharmaceutical biology 2020 Dec;58(1):686-694
Loganin inhibits macrophage M1 polarization and modulates sirt1/NF-κB signaling pathway to attenuate ulcerative colitis.
Liu S, Shen H, Li J, Gong Y, Bao H, Zhang J, Hu L, Wang Z, Gong J
Bioengineered 2020 Dec;11(1):628-639
Bioengineered 2020 Dec;11(1):628-639
Akebia Saponin D suppresses inflammation in chondrocytes via the NRF2/HO-1/NF-κB axis and ameliorates osteoarthritis in mice.
Gu M, Jin J, Ren C, Chen X, Gao W, Wang X, Wu Y, Tian N, Pan Z, Wu A, Zhou Y, Zhang X
Food & function 2020 Dec 1;11(12):10852-10863
Food & function 2020 Dec 1;11(12):10852-10863
Glycitin Suppresses Cartilage Destruction of Osteoarthritis in Mice.
Wang W, Yang R, Zhang M, Li J, Peng J, Xu M, Zhao Y, Li H, Pan X
Inflammation 2020 Aug;43(4):1312-1322
Inflammation 2020 Aug;43(4):1312-1322
Bone marrow mesenchymal stem cells combine with normothermic machine perfusion to improve rat donor liver quality-the important role of hepatic microcirculation in donation after circulatory death.
Yang L, Cao H, Sun D, Hou B, Lin L, Shen ZY, Song HL
Cell and tissue research 2020 Aug;381(2):239-254
Cell and tissue research 2020 Aug;381(2):239-254
Advanced glycation end products enhance macrophage polarization to the M1 phenotype via the HIF-1α/PDK4 pathway.
Han X, Ma W, Zhu Y, Sun X, Liu N
Molecular and cellular endocrinology 2020 Aug 20;514:110878
Molecular and cellular endocrinology 2020 Aug 20;514:110878
S-allylmercaptocysteine ameliorates lipopolysaccharide-induced acute lung injury in mice by inhibiting inflammation and oxidative stress via nuclear factor kappa B and Keap1/Nrf2 pathways.
Mo M, Li S, Dong Z, Li C, Sun Y, Li A, Zhao Z
International immunopharmacology 2020 Apr;81:106273
International immunopharmacology 2020 Apr;81:106273
4β-Hydroxywithanolide E from Goldenberry (Whole Fruits of Physalis peruviana L.) as a Promising Agent against Chronic Obstructive Pulmonary Disease.
Yang WJ, Chen XM, Wang SQ, Hu HX, Cheng XP, Xu LT, Ren DM, Wang XN, Zhao BB, Lou HX, Shen T
Journal of natural products 2020 Apr 24;83(4):1217-1228
Journal of natural products 2020 Apr 24;83(4):1217-1228
Silica particles disorganize the polarization of pulmonary macrophages in mice.
Zhao Y, Hao C, Bao L, Wang D, Li Y, Qu Y, Ding M, Zhao A, Yao W
Ecotoxicology and environmental safety 2020 Apr 15;193:110364
Ecotoxicology and environmental safety 2020 Apr 15;193:110364
Exosome-encapsulated miRNAs contribute to CXCL12/CXCR4-induced liver metastasis of colorectal cancer by enhancing M2 polarization of macrophages.
Wang D, Wang X, Si M, Yang J, Sun S, Wu H, Cui S, Qu X, Yu X
Cancer letters 2020 Apr 1;474:36-52
Cancer letters 2020 Apr 1;474:36-52
Role of Antioxidants in the Protection from Aging-Related Diseases.
Monti DM, Rigano MM, Monti SM, Peixoto HS
Oxidative medicine and cellular longevity 2019;2019:7450693
Oxidative medicine and cellular longevity 2019;2019:7450693
1-Trichloromethyl-1,2,3,4-tetrahydro-beta-carboline (TaClo) Induces the Apoptosis of Dopaminergic Neurons via Oxidative Stress and Neuroinflammation.
Yang Y, Pang B, Liu Z, Li J, Zhang Z, Zhang R, Hou X, Guo H, Chi L, Pang Q, Xin T
Oxidative medicine and cellular longevity 2019;2019:1292891
Oxidative medicine and cellular longevity 2019;2019:1292891
Relationship of Inflammatory Cytokines From M1-Type Microglia/Macrophages at the Injured Site and Lumbar Enlargement With Neuropathic Pain After Spinal Cord Injury in the CCL21 Knockout (plt) Mouse.
Honjoh K, Nakajima H, Hirai T, Watanabe S, Matsumine A
Frontiers in cellular neuroscience 2019;13:525
Frontiers in cellular neuroscience 2019;13:525
Nobiletin Inhibits IL-1β-Induced Inflammation in Chondrocytes via Suppression of NF-κB Signaling and Attenuates Osteoarthritis in Mice.
Lin Z, Wu D, Huang L, Jiang C, Pan T, Kang X, Pan J
Frontiers in pharmacology 2019;10:570
Frontiers in pharmacology 2019;10:570
Myeloid-Derived Suppressor Cells and γδT17 Cells Contribute to the Development of Gastric MALT Lymphoma in H. felis-Infected Mice.
Zhao Y, Lu F, Ye J, Ji M, Pang Y, Wang Y, Wang L, Li G, Sun T, Li J, Ma D, Ji C
Frontiers in immunology 2019;10:3104
Frontiers in immunology 2019;10:3104
Fusobacterium nucleatum Aggravates the Progression of Colitis by Regulating M1 Macrophage Polarization via AKT2 Pathway.
Liu L, Liang L, Liang H, Wang M, Lu B, Xue M, Deng J, Chen Y
Frontiers in immunology 2019;10:1324
Frontiers in immunology 2019;10:1324
Adenovirus‑mediated overexpression of bone morphogenetic protein‑9 promotes methionine choline deficiency‑induced non‑alcoholic steatohepatitis in non‑obese mice.
Li Q, Liu B, Breitkopf-Heinlein K, Weng H, Jiang Q, Dong P, Dooley S, Xu K, Ding H
Molecular medicine reports 2019 Sep;20(3):2743-2753
Molecular medicine reports 2019 Sep;20(3):2743-2753
Mechanism Underlying the Protective Effect of Selenium on NO-Induced Oxidative Damage in Bovine Mammary Epithelial Cells.
Guo Y, Guo X, Yan S, Zhang B, Shi B
Biological trace element research 2019 Sep;191(1):104-114
Biological trace element research 2019 Sep;191(1):104-114
An herbal-compound-based combination therapy that relieves cirrhotic ascites by affecting the L-arginine/nitric oxide pathway: A metabolomics-based systematic study.
Zhang K, Zhang Y, Li N, Xing F, Zhao J, Yang T, Liu C, Feng N
Journal of ethnopharmacology 2019 Sep 15;241:112034
Journal of ethnopharmacology 2019 Sep 15;241:112034
Sinomenine contributes to the inhibition of the inflammatory response and the improvement of osteoarthritis in mouse-cartilage cells by acting on the Nrf2/HO-1 and NF-κB signaling pathways.
Wu Y, Lin Z, Yan Z, Wang Z, Fu X, Yu K
International immunopharmacology 2019 Oct;75:105715
International immunopharmacology 2019 Oct;75:105715
Chrysophanol attenuates airway inflammation and remodeling through nuclear factor-kappa B signaling pathway in asthma.
Song G, Zhang Y, Yu S, Lv W, Guan Z, Sun M, Wang J
Phytotherapy research : PTR 2019 Oct;33(10):2702-2713
Phytotherapy research : PTR 2019 Oct;33(10):2702-2713
Therapeutic effect of yttrium oxide nanoparticles for the treatment of fulminant hepatic failure.
Song X, Shang P, Sun Z, Lu M, You G, Yan S, Chen G, Zhou H
Nanomedicine (London, England) 2019 Oct;14(19):2519-2533
Nanomedicine (London, England) 2019 Oct;14(19):2519-2533
Dehydroepiandrosterone alleviates E. Coli O157:H7-induced inflammation by preventing the activation of p38 MAPK and NF-κB pathways in mice peritoneal macrophages.
Zhao J, Cao J, Yu L, Ma H
Molecular immunology 2019 Oct;114:114-122
Molecular immunology 2019 Oct;114:114-122
γ-Oryzanol alleviates acetaminophen-induced liver injury: roles of modulating AMPK/GSK3β/Nrf2 and NF-κB signaling pathways.
Shu G, Qiu Y, Hao J, Fu Q, Deng X
Food & function 2019 Oct 16;10(10):6858-6872
Food & function 2019 Oct 16;10(10):6858-6872
Keel Fracture Causes Stress and Inflammatory Responses and Inhibits the Expression of the Orexin System in Laying Hens.
Wei H, Li C, Xin H, Li S, Bi Y, Li X, Li J, Zhang R, Bao J
Animals : an open access journal from MDPI 2019 Oct 15;9(10)
Animals : an open access journal from MDPI 2019 Oct 15;9(10)
Neuroprotection of Andrographolide Against Microglia-Mediated Inflammatory Injury and Oxidative Damage in PC12 Neurons.
Xu Y, Tang D, Wang J, Wei H, Gao J
Neurochemical research 2019 Nov;44(11):2619-2630
Neurochemical research 2019 Nov;44(11):2619-2630
Conditional Controlled Light/Dark Cycle Influences Exercise-Induced Benefits in a Rat Model with Osteoarthritis: In Vitro and In Vivo Study.
Hong Y, Lee S, Choi J, Jin Y, Won J, Hong Y
Journal of clinical medicine 2019 Nov 2;8(11)
Journal of clinical medicine 2019 Nov 2;8(11)
miR-let-7a suppresses α-Synuclein-induced microglia inflammation through targeting STAT3 in Parkinson's disease.
Zhang J, Dongwei Zhou, Zhang Z, Xinhui Qu, Kunwang Bao, Guohui Lu, Jian Duan
Biochemical and biophysical research communications 2019 Nov 19;519(4):740-746
Biochemical and biophysical research communications 2019 Nov 19;519(4):740-746
Chondrocyte apoptosis in rat mandibular condyles induced by dental occlusion due to mitochondrial damage caused by nitric oxide.
Ren H, Yang H, Xie M, Wen Y, Liu Q, Li X, Liu J, Xu H, Tang W, Wang M
Archives of oral biology 2019 May;101:108-121
Archives of oral biology 2019 May;101:108-121
High Molecular Weight Hyaluronan Suppresses Macrophage M1 Polarization and Enhances IL-10 Production in PM(2.5)-Induced Lung Inflammation.
Shi Q, Zhao L, Xu C, Zhang L, Zhao H
Molecules (Basel, Switzerland) 2019 May 7;24(9)
Molecules (Basel, Switzerland) 2019 May 7;24(9)
Cortistatin binds to TNF-α receptors and protects against osteoarthritis.
Zhao Y, Li Y, Qu R, Chen X, Wang W, Qiu C, Liu B, Pan X, Liu L, Vasilev K, Hayball J, Dong S, Li W
EBioMedicine 2019 Mar;41:556-570
EBioMedicine 2019 Mar;41:556-570
Sweroside Alleviated LPS-Induced Inflammation via SIRT1 Mediating NF-κB and FOXO1 Signaling Pathways in RAW264.7 Cells.
Wang R, Dong Z, Lan X, Liao Z, Chen M
Molecules (Basel, Switzerland) 2019 Mar 1;24(5)
Molecules (Basel, Switzerland) 2019 Mar 1;24(5)
In Vitro and In Vivo Anti-Inflammatory Effects of Polyphyllin VII through Downregulating MAPK and NF-κB Pathways.
Zhang C, Li C, Jia X, Wang K, Tu Y, Wang R, Liu K, Lu T, He C
Molecules (Basel, Switzerland) 2019 Mar 1;24(5)
Molecules (Basel, Switzerland) 2019 Mar 1;24(5)
Effect of dexmedetomidine on kidney injury in sepsis rats through TLR4/MyD88/NF-κB/iNOS signaling pathway.
Jin YH, Li ZT, Chen H, Jiang XQ, Zhang YY, Wu F
European review for medical and pharmacological sciences 2019 Jun;23(11):5020-5025
European review for medical and pharmacological sciences 2019 Jun;23(11):5020-5025
Berberine attenuates arthritis in adjuvant-induced arthritic rats associated with regulating polarization of macrophages through AMPK/NF-кB pathway.
Zhou J, Yu Y, Yang X, Wang Y, Song Y, Wang Q, Chen Z, Zong S, Fan M, Meng X, Xie C, Zhou F, Liu H, Wei F
European journal of pharmacology 2019 Jun 5;852:179-188
European journal of pharmacology 2019 Jun 5;852:179-188
Tempol alleviates chronic intermittent hypoxia-induced pancreatic injury through repressing inflammation and apoptosis.
Wang Y, Ai L, Hai B, Cao Y, Li R, Li H, Li Y
Physiological research 2019 Jun 30;68(3):445-455
Physiological research 2019 Jun 30;68(3):445-455
Analgesic and anti-inflammatory effects and molecular mechanisms of Kadsura heteroclita stems, an anti-arthritic Chinese Tujia ethnomedicinal herb.
Yu HH, Lin Y, Zeng R, Li X, Zhang T, Tasneem S, Chen C, Qiu YX, Li B, Liao J, Wang YH, Cai X, Wang W
Journal of ethnopharmacology 2019 Jun 28;238:111902
Journal of ethnopharmacology 2019 Jun 28;238:111902
BG-4 from Bitter Gourd (Momordica charantia) Differentially Affects Inflammation In Vitro and In Vivo.
Nieto-Veloza A, Wang Z, Zhong Q, Krishnan HB, Dia VP
Antioxidants (Basel, Switzerland) 2019 Jun 14;8(6)
Antioxidants (Basel, Switzerland) 2019 Jun 14;8(6)
Synthesis of andrographolide analogues and their neuroprotection and neurite outgrowth-promoting activities.
Xu Y, Wei H, Wang J, Wang W, Gao J
Bioorganic & medicinal chemistry 2019 Jun 1;27(11):2209-2219
Bioorganic & medicinal chemistry 2019 Jun 1;27(11):2209-2219
Aspirin inhibits inflammation and scar formation in the injury tendon healing through regulating JNK/STAT-3 signalling pathway.
Wang Y, He G, Tang H, Shi Y, Kang X, Lyu J, Zhu M, Zhou M, Yang M, Mu M, Chen W, Zhou B, Zhang J, Tang K
Cell proliferation 2019 Jul;52(4):e12650
Cell proliferation 2019 Jul;52(4):e12650
Involvement of NLRP3 inflammasome in methamphetamine-induced microglial activation through miR-143/PUMA axis.
Du L, Shen K, Bai Y, Chao J, Hu G, Zhang Y, Yao H
Toxicology letters 2019 Feb;301:53-63
Toxicology letters 2019 Feb;301:53-63
Ghrelin protects against contact dermatitis and psoriasiform skin inflammation by antagonizing TNF-α/NF-κB signaling pathways.
Qu R, Chen X, Hu J, Fu Y, Peng J, Li Y, Chen J, Li P, Liu L, Cao J, Wang W, Qiu C, Guo L, Vasilev K, Chen J, Zhou G, Li W, Zhao Y
Scientific reports 2019 Feb 4;9(1):1348
Scientific reports 2019 Feb 4;9(1):1348
Quercetin alleviates rat osteoarthritis by inhibiting inflammation and apoptosis of chondrocytes, modulating synovial macrophages polarization to M2 macrophages.
Hu Y, Gui Z, Zhou Y, Xia L, Lin K, Xu Y
Free radical biology & medicine 2019 Dec;145:146-160
Free radical biology & medicine 2019 Dec;145:146-160
GRK2 Mediated Abnormal Transduction of PGE2-EP4-cAMP-CREB Signaling Induces the Imbalance of Macrophages Polarization in Collagen-Induced Arthritis Mice.
Yang X, Li S, Zhao Y, Li S, Zhao T, Tai Y, Zhang B, Wang X, Wang C, Chen J, Wang Q, Zhang L, Xu D, Chang Y, Wei W
Cells 2019 Dec 8;8(12)
Cells 2019 Dec 8;8(12)
Rice Protein Exerts Anti-Inflammatory Effect in Growing and Adult Rats via Suppressing NF-κB Pathway.
Wang Z, Liang M, Li H, Cai L, Yang L
International journal of molecular sciences 2019 Dec 6;20(24)
International journal of molecular sciences 2019 Dec 6;20(24)
Trans-10-hydroxy-2-decenoic acid alleviates LPS-induced blood-brain barrier dysfunction by activating the AMPK/PI3K/AKT pathway.
You M, Miao Z, Pan Y, Hu F
European journal of pharmacology 2019 Dec 15;865:172736
European journal of pharmacology 2019 Dec 15;865:172736
Interleukin-1 receptor associated kinase (IRAK)-M -mediated type 2 microglia polarization ameliorates the severity of experimental autoimmune encephalomyelitis (EAE).
Liu B, Gu Y, Pei S, Peng Y, Chen J, Pham LV, Shen HY, Zhang J, Wang H
Journal of autoimmunity 2019 Aug;102:77-88
Journal of autoimmunity 2019 Aug;102:77-88
Microglia Activated by Excess Cortisol Induce HMGB1 Acetylation and Neuroinflammation in the Hippocampal DG Region of Mice Following Cold Exposure.
Xu B, Lang LM, Li SZ, Guo JR, Wang JF, Yang HM, Lian S
Biomolecules 2019 Aug 30;9(9)
Biomolecules 2019 Aug 30;9(9)
Icariin attenuates neuroinflammation and exerts dopamine neuroprotection via an Nrf2-dependent manner.
Zhang B, Wang G, He J, Yang Q, Li D, Li J, Zhang F
Journal of neuroinflammation 2019 Apr 22;16(1):92
Journal of neuroinflammation 2019 Apr 22;16(1):92
Targeted Delivery of miRNA 155 to Tumor Associated Macrophages for Tumor Immunotherapy.
Zang X, Zhang X, Zhao X, Hu H, Qiao M, Deng Y, Chen D
Molecular pharmaceutics 2019 Apr 1;16(4):1714-1722
Molecular pharmaceutics 2019 Apr 1;16(4):1714-1722
Aryl Hydrocarbon Receptor Regulates Apoptosis and Inflammation in a Murine Model of Experimental Autoimmune Uveitis.
Huang Y, He J, Liang H, Hu K, Jiang S, Yang L, Mei S, Zhu X, Yu J, Kijlstra A, Yang P, Hou S
Frontiers in immunology 2018;9:1713
Frontiers in immunology 2018;9:1713
Effects of Acute Cold Stress After Long-Term Cold Stimulation on Antioxidant Status, Heat Shock Proteins, Inflammation and Immune Cytokines in Broiler Heart.
Wei H, Zhang R, Su Y, Bi Y, Li X, Zhang X, Li J, Bao J
Frontiers in physiology 2018;9:1589
Frontiers in physiology 2018;9:1589
Effective Amelioration of Liver Fibrosis Through Lentiviral Vector Carrying Toxoplasma gondii gra15(II) in Murine Model.
Liu L, Jin M, Tao Q, Yu L, Du J, Wang C, Luo Q, Xing T, Xu Y, Shen J, Chu D
Frontiers in immunology 2018;9:1572
Frontiers in immunology 2018;9:1572
Fangchinoline Ameliorates the Expressions of Angiogenic Molecule in Cerebral Ischemia Induced Neuronal Degeneration in Neonatal Rats.
Daicheng H, Shiwen X, Huaping Z, Yong L, Qianqian Z, Changxia H
Translational neuroscience 2018;9:117-122
Translational neuroscience 2018;9:117-122
Neuroprotective Effects of dl-3-n-Butylphthalide against Doxorubicin-Induced Neuroinflammation, Oxidative Stress, Endoplasmic Reticulum Stress, and Behavioral Changes.
Liao D, Xiang D, Dang R, Xu P, Wang J, Han W, Fu Y, Yao D, Cao L, Jiang P
Oxidative medicine and cellular longevity 2018;2018:9125601
Oxidative medicine and cellular longevity 2018;2018:9125601
Flavonoid-Rich Ethanol Extract from the Leaves of Diospyros kaki Attenuates D-Galactose-Induced Oxidative Stress and Neuroinflammation-Mediated Brain Aging in Mice.
Ma Y, Ma B, Shang Y, Yin Q, Wang D, Xu S, Hong Y, Hou X, Liu X
Oxidative medicine and cellular longevity 2018;2018:8938207
Oxidative medicine and cellular longevity 2018;2018:8938207
Ingredients from Litsea garrettii as Potential Preventive Agents against Oxidative Insult and Inflammatory Response.
Li YR, Li GH, Sun L, Li L, Liu Y, Kong DG, Wang SQ, Ren DM, Wang XN, Lou HX, Shen T
Oxidative medicine and cellular longevity 2018;2018:7616852
Oxidative medicine and cellular longevity 2018;2018:7616852
Berberine Protects Secondary Injury in Mice with Traumatic Brain Injury Through Anti-oxidative and Anti-inflammatory Modulation.
Huang SX, Qiu G, Cheng FR, Pei Z, Yang Z, Deng XH, Zhu JH, Chen L, Chen CC, Lin WF, Liu Y, Liu Z, Zhu FQ
Neurochemical research 2018 Sep;43(9):1814-1825
Neurochemical research 2018 Sep;43(9):1814-1825
GABAB receptor mediate hippocampal neuroinflammation in adolescent male and female mice after cold expose.
Xu B, Lian S, Li SZ, Guo JR, Wang JF, Wang D, Zhang LP, Yang HM
Brain research bulletin 2018 Sep;142:163-175
Brain research bulletin 2018 Sep;142:163-175
Astragaloside IV improves vascular endothelial dysfunction by inhibiting the TLR4/NF-κB signaling pathway.
Leng B, Tang F, Lu M, Zhang Z, Wang H, Zhang Y
Life sciences 2018 Sep 15;209:111-121
Life sciences 2018 Sep 15;209:111-121
S100A8/A9 induces microglia activation and promotes the apoptosis of oligodendrocyte precursor cells by activating the NF-κB signaling pathway.
Wu M, Xu L, Wang Y, Zhou N, Zhen F, Zhang Y, Qu X, Fan H, Liu S, Chen Y, Yao R
Brain research bulletin 2018 Oct;143:234-245
Brain research bulletin 2018 Oct;143:234-245
Diosmetin Attenuates Akt Signaling Pathway by Modulating Nuclear Factor Kappa-Light-Chain-Enhancer of Activated B Cells (NF-κB)/Inducible Nitric Oxide Synthase (iNOS) in Streptozotocin (STZ)-Induced Diabetic Nephropathy Mice.
Jiang Y, Liu J, Zhou Z, Liu K, Liu C
Medical science monitor : international medical journal of experimental and clinical research 2018 Oct 2;24:7007-7014
Medical science monitor : international medical journal of experimental and clinical research 2018 Oct 2;24:7007-7014
Decidual macrophage M1 polarization contributes to adverse pregnancy induced by Toxoplasma gondii PRU strain infection.
Liu X, Jiang M, Ren L, Zhang A, Zhao M, Zhang H, Jiang Y, Hu X
Microbial pathogenesis 2018 Nov;124:183-190
Microbial pathogenesis 2018 Nov;124:183-190
l-Arginine induces antioxidant response to prevent oxidative stress via stimulation of glutathione synthesis and activation of Nrf2 pathway.
Liang M, Wang Z, Li H, Cai L, Pan J, He H, Wu Q, Tang Y, Ma J, Yang L
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2018 May;115:315-328
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2018 May;115:315-328
Silica-induced initiation of circular ZC3H4 RNA/ZC3H4 pathway promotes the pulmonary macrophage activation.
Yang X, Wang J, Zhou Z, Jiang R, Huang J, Chen L, Cao Z, Chu H, Han B, Cheng Y, Chao J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2018 Jun;32(6):3264-3277
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2018 Jun;32(6):3264-3277
Lipopolysaccharide Induces Subacute Cerebral Microhemorrhages with Involvement of Nitric Oxide Synthase in Rats.
Zeng J, Zhào H, Liu Z, Zhang W, Huang Y
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2018 Jul;27(7):1905-1913
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2018 Jul;27(7):1905-1913
Anti-inflammatory effect of tranexamic acid against trauma-hemorrhagic shock-induced acute lung injury in rats.
Teng Y, Feng C, Liu Y, Jin H, Gao Y, Li T
Experimental animals 2018 Jul 30;67(3):313-320
Experimental animals 2018 Jul 30;67(3):313-320
Investigation of constituents from Cinnamomum camphora (L.) J. Presl and evaluation of their anti-inflammatory properties in lipopolysaccharide-stimulated RAW 264.7 macrophages.
Li YR, Fu CS, Yang WJ, Wang XL, Feng D, Wang XN, Ren DM, Lou HX, Shen T
Journal of ethnopharmacology 2018 Jul 15;221:37-47
Journal of ethnopharmacology 2018 Jul 15;221:37-47
Asperuloside and Asperulosidic Acid Exert an Anti-Inflammatory Effect via Suppression of the NF-κB and MAPK Signaling Pathways in LPS-Induced RAW 264.7 Macrophages.
He J, Lu X, Wei T, Dong Y, Cai Z, Tang L, Liu M
International journal of molecular sciences 2018 Jul 12;19(7)
International journal of molecular sciences 2018 Jul 12;19(7)
Photobiomodulation therapy promotes neurogenesis by improving post-stroke local microenvironment and stimulating neuroprogenitor cells.
Yang L, Tucker D, Dong Y, Wu C, Lu Y, Li Y, Zhang J, Liu TC, Zhang Q
Experimental neurology 2018 Jan;299(Pt A):86-96
Experimental neurology 2018 Jan;299(Pt A):86-96
Toxoplasma gondii GRA15(II) effector-induced M1 cells ameliorate liver fibrosis in mice infected with Schistosomiasis japonica.
Xie Y, Wen H, Yan K, Wang S, Wang X, Chen J, Li Y, Xu Y, Zhong Z, Shen J, Chu D
Cellular & molecular immunology 2018 Feb;15(2):120-134
Cellular & molecular immunology 2018 Feb;15(2):120-134
Tempol relieves lung injury in a rat model of chronic intermittent hypoxia via suppression of inflammation and oxidative stress.
Wang Y, Hai B, Ai L, Cao Y, Li R, Li H, Li Y
Iranian journal of basic medical sciences 2018 Dec;21(12):1238-1244
Iranian journal of basic medical sciences 2018 Dec;21(12):1238-1244
Protective effect of the ethanol extract from Ligusticum chuanxiong rhizome against streptozotocin-induced diabetic nephropathy in mice.
Yang WJ, Li YR, Gao H, Wu XY, Wang XL, Wang XN, Xiang L, Ren DM, Lou HX, Shen T
Journal of ethnopharmacology 2018 Dec 5;227:166-175
Journal of ethnopharmacology 2018 Dec 5;227:166-175
Quercetin ameliorates kidney injury and fibrosis by modulating M1/M2 macrophage polarization.
Lu H, Wu L, Liu L, Ruan Q, Zhang X, Hong W, Wu S, Jin G, Bai Y
Biochemical pharmacology 2018 Aug;154:203-212
Biochemical pharmacology 2018 Aug;154:203-212
NOD2 promotes dopaminergic degeneration regulated by NADPH oxidase 2 in 6-hydroxydopamine model of Parkinson's disease.
Cheng L, Chen L, Wei X, Wang Y, Ren Z, Zeng S, Zhang X, Wen H, Gao C, Liu H
Journal of neuroinflammation 2018 Aug 29;15(1):243
Journal of neuroinflammation 2018 Aug 29;15(1):243
Fish oil supplementation attenuates neuroinflammation and alleviates depressive-like behavior in rats submitted to repeated lipopolysaccharide.
Dang R, Zhou X, Tang M, Xu P, Gong X, Liu Y, Jiao H, Jiang P
European journal of nutrition 2018 Apr;57(3):893-906
European journal of nutrition 2018 Apr;57(3):893-906
Butaselen prevents hepatocarcinogenesis and progression through inhibiting thioredoxin reductase activity.
Zheng X, Ma W, Sun R, Yin H, Lin F, Liu Y, Xu W, Zeng H
Redox biology 2018 Apr;14:237-249
Redox biology 2018 Apr;14:237-249
Treadmill Exercise Exerts Neuroprotection and Regulates Microglial Polarization and Oxidative Stress in a Streptozotocin-Induced Rat Model of Sporadic Alzheimer's Disease.
Lu Y, Dong Y, Tucker D, Wang R, Ahmed ME, Brann D, Zhang Q
Journal of Alzheimer's disease : JAD 2017;56(4):1469-1484
Journal of Alzheimer's disease : JAD 2017;56(4):1469-1484
Iridoids with Genipin Stem Nucleus Inhibit Lipopolysaccharide-Induced Inflammation and Oxidative Stress by Blocking the NF-κB Pathway in Polycystic Ovary Syndrome.
Zuo T, Zhu M, Xu W, Wang Z, Song H
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(5):1855-1865
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(5):1855-1865
NS1 of H7N9 Influenza A Virus Induces NO-Mediated Cellular Senescence in Neuro2a Cells.
Yan Y, Du Y, Zheng H, Wang G, Li R, Chen J, Li K
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(4):1369-1380
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(4):1369-1380
Peli1 Contributions in Microglial Activation, Neuroinflammatory Responses and Neurological Deficits Following Experimental Subarachnoid Hemorrhage.
Huang XP, Peng JH, Pang JW, Tian XC, Li XS, Wu Y, Li Y, Jiang Y, Sun XC
Frontiers in molecular neuroscience 2017;10:398
Frontiers in molecular neuroscience 2017;10:398
Adulthood Exposure to Lipopolysaccharide Exacerbates the Neurotoxic and Inflammatory Effects of Rotenone in the Substantia Nigra.
Huang C, Zhu L, Li H, Shi FG, Wang GQ, Wei YZ, Liu J, Zhang F
Frontiers in molecular neuroscience 2017;10:131
Frontiers in molecular neuroscience 2017;10:131
GRP78 plays an integral role in tumor cell inflammation-related migration induced by M2 macrophages.
Zhang L, Li Z, Ding G, La X, Yang P, Li Z
Cellular signalling 2017 Sep;37:136-148
Cellular signalling 2017 Sep;37:136-148
NF-κB-mediated inflammation correlates with calcium overload under arsenic trioxide-induced myocardial damage in Gallus gallus.
Li S, Wang Y, Zhao H, He Y, Li J, Jiang G, Xing M
Chemosphere 2017 Oct;185:618-627
Chemosphere 2017 Oct;185:618-627
Hepatoprotective effect of quercetin against LPS/d-GalN induced acute liver injury in mice by inhibiting the IKK/NF-κB and MAPK signal pathways.
Peng Z, Gong X, Yang Y, Huang L, Zhang Q, Zhang P, Wan R, Zhang B
International immunopharmacology 2017 Nov;52:281-289
International immunopharmacology 2017 Nov;52:281-289
A novel IL-1RA-PEP fusion protein with enhanced brain penetration ameliorates cerebral ischemia-reperfusion injury by inhibition of oxidative stress and neuroinflammation.
Zhang DD, Zou MJ, Zhang YT, Fu WL, Xu T, Wang JX, Xia WR, Huang ZG, Gan XD, Zhu XM, Xu DG
Experimental neurology 2017 Nov;297:1-13
Experimental neurology 2017 Nov;297:1-13
Reactive oxygen species-responsive polymeric nanoparticles for alleviating sepsis-induced acute liver injury in mice.
Chen G, Deng H, Song X, Lu M, Zhao L, Xia S, You G, Zhao J, Zhang Y, Dong A, Zhou H
Biomaterials 2017 Nov;144:30-41
Biomaterials 2017 Nov;144:30-41
Procyanidins extracted from the litchi pericarp ameliorate atherosclerosis in ApoE knockout mice: their effects on nitric oxide bioavailability and oxidative stress.
Rong S, Hu X, Zhao S, Zhao Y, Xiao X, Bao W, Liu L
Food & function 2017 Nov 15;8(11):4210-4216
Food & function 2017 Nov 15;8(11):4210-4216
Matrine promotes NT3 expression in CNS cells in experimental autoimmune encephalomyelitis.
Zhang ML, Zhang XJ, Kang J, Zhang HJ, Chen XL, Liu N, Liu SQ, Ma WD, Zhang GX, Zhu L
Neuroscience letters 2017 May 10;649:100-106
Neuroscience letters 2017 May 10;649:100-106
Alantolactone induces apoptosis, promotes STAT3 glutathionylation and enhances chemosensitivity of A549 lung adenocarcinoma cells to doxorubicin via oxidative stress.
Maryam A, Mehmood T, Zhang H, Li Y, Khan M, Ma T
Scientific reports 2017 Jul 24;7(1):6242
Scientific reports 2017 Jul 24;7(1):6242
Quillaja saponaria bark saponin protects Wistar rats against ferrous sulphate-induced oxidative and inflammatory liver damage.
Ahmed Abdel-Reheim M, Messiha BAS, Abo-Saif AA
Pharmaceutical biology 2017 Dec;55(1):1972-1983
Pharmaceutical biology 2017 Dec;55(1):1972-1983
The inflammatory responses in Cu-mediated elemental imbalance is associated with mitochondrial fission and intrinsic apoptosis in Gallus gallus heart.
Li S, Zhao H, Wang Y, Shao Y, Li J, Liu J, Xing M
Chemosphere 2017 Dec;189:489-497
Chemosphere 2017 Dec;189:489-497
Inflammatory and oxidative stress‑associated factors in chronic intermittent hypoxia in Chinese patients, rats, lymphocytes and endotheliocytes.
Ren H, Hu K
Molecular medicine reports 2017 Dec;16(6):8092-8102
Molecular medicine reports 2017 Dec;16(6):8092-8102
CAPE-pNO(2) ameliorated diabetic nephropathy through regulating the Akt/NF-κB/ iNOS pathway in STZ-induced diabetic mice.
Wang X, Li D, Fan L, Xiao Q, Zuo H, Li Z
Oncotarget 2017 Dec 29;8(70):114506-114525
Oncotarget 2017 Dec 29;8(70):114506-114525
Melatonin ameliorates restraint stress-induced oxidative stress and apoptosis in testicular cells via NF-κB/iNOS and Nrf2/ HO-1 signaling pathway.
Guo Y, Sun J, Li T, Zhang Q, Bu S, Wang Q, Lai D
Scientific reports 2017 Aug 29;7(1):9599
Scientific reports 2017 Aug 29;7(1):9599
Neuroprotective effects of Kaempferide-7-O-(4″-O-acetylrhamnosyl)-3-O-rutinoside on cerebral ischemia-reperfusion injury in rats.
Wang S, Xu H, Xin Y, Li M, Fu W, Wang Y, Lu Z, Yu X, Sui D
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver using 18985-1-AP(NOS2 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The iNOS antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human iNOS. This antibody recognizes human,mouse,rat antigen. The iNOS antibody has been validated for the following applications: ELISA, IHC analysis.
