Explore
Validate
Learn
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [349]
- Comments [0]
- Validations [0]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 22226-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- iNOS antibody
- Antibody type
- Polyclonal
- Description
- iNOS antibody (Cat. #22226-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references After Traumatic Brain Injury, EPHA4 Enhances Endoplasmic Reticulum Stress to Promote M1 Microglial Polarization Through the MAPK Signaling Pathway.
Platelet-rich plasma-derived microRNA let-7a-5p alleviates knee osteoarthritis by regulating macrophage polarization and improving inflammatory microenvironment.
Meningeal lymphatic vessel dysfunction exacerbates brain injury in CVST mice via endoplasmic reticulum and oxidative stress pathways.
A near-infrared regulated programmable multi-mode periosteum scaffold for sequential healing of infected bone defects.
Stromal cell-derived itaconate promotes endometriosis via macrophage NRF2 and lysosomal pH modulation.
Histone H3K9 lactylation activates the TXNIP/NLRP3 pathway to drive macrophage inflammation after spinal cord injury.
Antimicrobial peptide chensinin-1b attenuates T2DM progression in atherosclerotic ApoE(-/-) mice.
Partial NaCl replacement with arginine during brining influences apoptosis and post-brining quality of grass carp fillets.
Self-Assembled Quercetin-Mecobalamin Nanoparticles Mitigate Ischemic Stroke Injury via Enhanced Neuroprotection and Microglial Modulation.
Integrative epidemiology and multi-omics reveal a frailty-associated ACKR1 redox axis linking cadmium exposure to atherosclerosis.
Modification of 3D printed porous titanium implants with on-demand delivery of curcumin and stromal cell derived factor-1 for osseointegration improvement.
Dynamic ROS-responsive hyperbranched polymer-based neuroprotective drug delivery system for pathogenesis-adaptive sequential therapy of cerebral ischemic stroke.
Modulation of immune cell differentiation by Prunella vulgaris L. essential oil in pulmonary sarcoidosis treatment.
Imperatorin ameliorates metabolic dysfunction-associated fatty liver disease through modulating Suv39h1/Fabps/Cept1 signalling pathway.
Dextrorotatory kynurenine suppresses acute rejection through inhibiting M1 macrophage-mediated inflammation.
Nature-inspired confined cascade enzyme nanoreactors for targeted atherosclerosis therapy.
Curcumin protects against difenoconazole-induced kidney injury in carp by inhibiting ferroptosis through the Nrf2/GPX4 axis.
ZXDB Drives Macrophage Inflammatory Programming in Sepsis-Induced Acute Kidney Injury by Recruiting EIF4A3 to Enhance ACACA Translation.
Nanocolloidal Hydrogel Coatings With Multiple Functions for Antithrombogenic Biointerfaces.
3'-Hydroxypterostilbene Alleviates Obesity and Lipoprotein Metabolism Dysregulation by Reshaping Gut Microbiota in High-Fat Diet-Induced Obese Mice.
Single-Atom Nanozyme Driven Lactate Reversal Fuels Oxidative Metabolism and Represses Lactylation to Heal Diabetic Wounds.
Microglial GLUL loss worsens TBI outcomes by amplifying the arginine-citrulline pathway.
PRMT1 regulates glioblastoma stemness and immunosuppression via nitric oxide metabolism: Multi-cohort analysis and experimental validation.
TRPM7 inhibition alleviates acute gouty arthritis in mice by suppressing M1 polarization through the EDN1/EDNRB axis.
YAP in synovial macrophages mitigates mechanically-induced osteoarthritis by preserving mitochondrial fusion.
Discovery of novel HDAC6 inhibitors based on the diphenyl-1,2,4-oxadiazole scaffold with potential efficacy in alleviating inflammation- and chemotherapy- associated mechanical hypersensitivity.
Methyl 3-chloroasterric acid exerted anti-neuroinflammatory and antidepressant effects through the downregulation of P2Y1R.
Deficiency of Med1 in keratinocytes augments dermal fibrosis and inflammation in scleroderma.
Overexpression of mitofusin 2 ameliorates inflammation and oxidative stress in lipopolysaccharide-induced mastitis model by regulating phosphofurin acidic cluster sorting protein 2.
CMTM6 promotes synovial proliferation and macrophage polarization by preventing ubiquitination of TAK1 in rheumatoid arthritis.
Diallyl Trisulfide Suppresses Tumor-Associated Macrophage M2-Like Polarization and Recruitment and Improves the Tumor Microenvironment Through Blocking CCL5/STAT3 Signaling Pathway Against Lung Cancer.
Immunomodulatory mesoporous bioactive glass/interleukin-4 nanocomplex promotes bone regeneration.
Daucosterol ameliorates acute inflammation and fibrosis following myocardial infarction via regulation of the ZBTB16 protein.
Pharmacological inhibition of PGK1 by genipin reduces inflammation and oxidative damage in osteoarthritis.
Therapeutic potential of hydroxytyrosol against bisphenol S-induced toxicity to microglia via targeting cytochrome P450 1A1 (CYP1A1).
Nanogel Integrated Zwitterionic Injectable Hydrogel with Sequential Drug-Releasing Capability for the Programmable Repair of Spinal Cord Injury.
Multimodal hybrid nanozymes with antioxidant catalytic and antibiotic-free antibacterial activities for enhanced multi-target sepsis therapy.
Caveolin-2 Knockdown Alleviated Sepsis-induced Acute Lung Injury Via Promoting Macrophage M2 Polarization and Inhibiting Apoptosis by Hippo Signaling Pathway.
A Novel YTHDF2/SIGMAR1 Axis in Astrocytes Regulates Neuroinflammation and Cognitive Impairment in Diabetic Encephalopathy.
Narciclasine Alleviates Endothelial Inflammation and Atherosclerosis Initiation by Inhibiting Histone Lactylation-Mediated NF-κB Activation.
Explore the chemical components of Angong Niuhuang Pill and its potential mechanisms for fever treatment based on UHPLC-Q-Exactive orbitrap HRMS, transcriptomics, and experiment verification.
Mechanistic insights into the effects of Norisoboldine on intestinal immunity and neuroinflammation in a mouse model of slow transit constipation with depression.
Baicalin inhibits bladder cancer progression by suppressing PD-L1-mediated M2 macrophage polarization via ALDH2.
Genistein Ameliorates the Ischemic State of Random Skin Flap by Regulating Macrophage Polarization Through AMPK/SIRT1 Signaling Pathway.
TWEAK exacerbates allergic conjunctivitis via PKM2-dependent NF-κB activation and macrophage M1 polarization.
Treadmill running modulates infrapatellar fat pad remodeling in osteoarthritic rats in an intensity-dependent manner.
Cepharanthine alleviated chronic prostatitis/chronic pelvic pain syndrome by activating Nrf2 and inhibiting the NF-κB pathway.
[Isovitexin alleviates myocardial oxidative stress injury in diabetic mice by enhancing myocardial SIRT3 expression and reducing oxidative stress].
Ly93 Inhibits Sphingomyelin Synthesis and Attenuates Inflammation and Injury in Dry Eye Conjunctival Organoids.
Tet2 deficiency-induced expansion of monocyte-derived macrophages promotes liver fibrosis.
Hypoxia-preconditioned cardiomyocyte-derived extracellular vesicles alleviate myocardial ischemic injury by reprogramming macrophage polarization via the Fgl2/NF-κB pathway.
Immunomodulatory effects of biodegradable Mg-Cu-Zn alloy in esophageal cancer.
Unravelling the potential of Vitex negundo leaf extract in LPS-induced acute lung injury in mice through modulation of the TLR-4/NF-κB p65/iNOS pathway: Insights from integrated phytochemical characterization, in silico, and in vivo analysis.
Tussilagone attenuated cigarette smoke-induced chronic obstructive pulmonary disease through regulating Nrf2 and NF-κB/NLRP3 inflammasome via directly targeting cysteine 434 of KEAP1.
Injectable microgels carrying engineered biomimetic nanoparticles for osteoarthritis therapy via dual-targeted senescent chondrocyte clearance and endogenous repair promotion.
Ultrasound-activated piezoelectric Silk-PVDF hydrogel reprograms the osteoimmune microenvironment via NRF2 signaling for accelerated bone regeneration.
Polyhedral oligomeric silsesquioxane-functionalized carboxymethyl chitin microspheres via irradiation-induced grafting for hemostasis and tissue repair in post-extraction sockets.
ANGPT2/Tie2 Enhances H3K18la-Mediated Macrophage M2 Polarization to Promote Endothelial Cell Proliferation in the Chronically Ischaemic Brain.
The Dual Role of Gastrodin in Spinal Cord Injury: Microglial Phenotype Switching and Neuronal Survival via PI3K/AKT Activation.
Wine-Processed Cornus officinalis Ameliorates Osteoarthritis via Modulating M1/M2 Macrophage Polarization.
Thermosensitive hydrogel delivers nanoparticles for the modulation of immune homeostasis for salpingitis therapy.
Lycium Barbarum Polysaccharide Attenuates Staphylococcus aureus-Induced Mastitis via the Gut Microbiota-Derived Indole-3-Propionic Acid/AhR-IL-22-STAT3 Axis.
Platelet factors 4 produces an antidepressant effect in mice via inhibition of neuroinflammation.
Targeting Reactive Oxygen Species and Inflammation in Sepsis-Induced Liver Injury with Naturally Derived Superoxide Dismutase-Mimicking Carbon Dots.
A Biodegradable Zinc Alloy Membrane with Regulation of Macrophage Polarization for Early Vascularized Bone Regeneration.
Ginsenoside Rh2-Pretreated Mesenchymal Stem Cell Exosomes Ameliorate Collagen-Induced Arthritis via N6-Methyladenosine Methylation.
Tumor-associated macrophages drive heterogenetic CD10(High) cancer stem cells to implement tumor-associated neutrophils reprogramming in oral squamous cell carcinoma.
Protective effect of Pinacidil on hypoxic-reoxygenated cardiomyocytes in vitro and in vivo via HIF-1α/HRE pathway.
Berberine-taxifolin co-administration attenuates inflammatory response and intestinal barrier injury via nf-κB/NLRP3 suppression in colitis.
IL-19 suppresses Hippo signaling via modulating YAP1 phosphorylation in osteoarthritis.
Integrative analysis of single-cell and microarray data reveals SPI1-centered macrophage regulatory signatures in ulcerative colitis.
Acetylcholine from tuft cells promotes M2 macrophages polarization in Hirschsprung-associated enterocolitis.
Curdione combined with borneol treats bacterial mixed HPV infection by regulating the crosstalk among immune cells.
Bioinspired exosome-SiO(2) nanohybrid therapeutic for rheumatoid arthritis treatment.
Polyphenol and metal ion-reinforced supermolecular hydrogels incorporating nanofiber drug and peptide for annulus fibrosus regeneration.
Normal butanol fraction of Polygonum hydropiper L. flavonoids reduces inflammation caused by PCV2 infections in cell and mouse models.
Ascorbic acid deficiency promotes metabolic remodeling and pulmonary fibrosis that leads to respiratory failure in Sod1 and Akr1a double-knockout mice.
Peptide-Enhanced Bioactive Hydrogel Combined with Photodynamic-Phage Synergistic Antibacterial Therapy System Accelerates Infected Wound Healing.
Novel oncolytic adenovirus-based PEPvIII vaccine displays a super antitumor effect in glioma models.
Dual stimulus-responsive dECM cryogel sequentially regulate bone microenvironment for one-step surgical therapy of chronic osteomyelitis.
Construction and characteristics of an adjustable biomechanical in vitro corneal stromal model simulating keratoconus pathological features.
Magnoflorine ameliorates cartilage degradation in osteoarthritis through inhibition of mitochondrial reactive oxygen species-mediated activation of the NLRP3 inflammasome.
Chronic intermittent hypoxia exacerbates the progression of NAFLD via SPP1-mediated inflammatory polarization in macrophages.
Translating m6A-Glycolysis Discovery into Therapy: GOQD-Based Multifunctional Bioactive Scaffolds Rejuvenates Bone Repair in Senescence.
Targeting inducible nitric oxide synthase with 1400W mitigates septic acute lung injury through inhibiting SLC7A11/GPX4 mediated ferroptosis.
Alamandine inhibits pathological retinal neovascularization by targeting the MrgD-mediated HIF-1α/VEGF pathway.
Synergistic potential of Berberine and Wogonin improved adipose inflammation and insulin resistance associated with obesity through HIF-α axis.
Poliumoside Alleviates Neuroinflammation and Oxidative Stress After Spinal Cord Injury by Activating the PI3K/AKT/mTOR Signaling Pathway.
Design of spiro-heterocyclic substituted diaminonaphthalene Keap1-Nrf2 protein-protein interaction inhibitors as novel anti-depressant agents.
M2-exo promote orthodontic bone remodeling via the MeCP2-TCF20-HDAC1 axis.
Inhibition of inducible nitric oxide synthase (iNOS) alleviates thoracic aortic aneurysm by regulating mitochondrial dynamics.
Microglia-Derived Exosomal miR-223-3p Targets the RhoB-NF-κB-CCL11 Axis in Astrocytes and Relieves Neuronal Damage in Subarachnoid Hemorrhage.
Tangeretin protects the kidney from ischemia-reperfusion injury by inhibiting inflammatory response through downregulation of MAOA.
BFGF alleviates diabetic endothelial dysfunction by downregulating Endoplasmic reticulum stress.
Galectin-9 promotes colon cancer development by polarizing macrophages toward the M2 phenotype.
Protocatechuic aldehyde promotes diabetic wound healing by enhancing angiogenesis via H3K18 lactylation-mediated Acvr1c expression.
LXR-β regulates microglial efferocytosis and neuroinflammation in CPSP via STAT6 activation.
SGMS2+ macrophages enhance NR4A3hi NK cell infiltration to improve prognosis and PD-1 treatment efficacy in hepatocellular carcinoma.
Rg1-preconditioned adipose-derived mesenchymal stromal cells alleviate colitis via exosome-mediated Inhibition of macrophage glycolysis through RAS signaling.
Targeted suppression of CCR7/NF-κB signaling by apoptotic body-inspired colchicine nanovesicles halts atherosclerotic progression.
Yiqi Huayu Jiedu decoction enhances pathological response in neoadjuvant chemotherapy-treated gastric cancer patients: A prospective, randomized controlled trial.
M2 macrophages and tumor cells engage in a metabolic feedback loop to drive HCC progression.
Chitosan-based adhesive patch with anti-inflammatory, pro-healing, and immunomodulatory properties for dural defect repair.
Topical cyclodextrin minocycline inclusion complex inhibited the inflammation in blepharitis-related dry eye disease.
CDK5 regulates PPARγ/NF-κB signaling to exacerbate obesity-related osteoarthritis via modulating macrophage polarization and chondrocyte apoptosis.
Asymmetric Janus Electrospun Nanofiber Wound Dressing Infused with Antibacterial and Anti-inflammatory Properties.
The compound (E)-2-(3,4-dihydroxystyryl)-3-hydroxy-4H-pyran-4-one alleviates neuroinflammation and cognitive impairment in a mouse model of Alzheimer's disease.
LA-peptide Hydrogel-Regulation of macrophage and fibroblast fates and their crosstalk via attenuating TGF-β to promote scarless wound healing.
PARP14 inhibits microglial activation via NNT to alleviate depressive-like behaviors in mice.
GTS-21 alleviates sepsis-induced atrial fibrillation susceptibility by modulating macrophage polarization and Neuregulin-1 secretion.
Inhibition of CDK5 signaling mediated inflammation in macrophages promotes cutaneous wound healing.
METTL3-Driven m6A Modification of Cpt1a Gene in High Fat Diet Related Liver Cancer Tumor Macrophages Facilitates Type II Macrophage Differentiation.
Toxoplasma calcium-dependent protein kinases 3 mediates M1 macrophage polarization by targeting host Arginase-1.
M2-ApoBDs as a therapeutic strategy for systemic lupus erythematosus: targeted macrophage reprogramming and treg differentiation.
Herkinorin ameliorates neuronal damage in a pentylenetetrazol-induced epilepsy rat model through altering microglial and astrocytic activation by inhibiting PARP1 and NF-κB.
IL-27 accelerates diabetic wound healing by modulating macrophage polarization.
Baicalin mitigates alcoholic-associated liver disease via SOCS1-driven reprogramming of macrophages.
Nicotinamide Adenine Dinucleotide-Loaded Lubricated Hydrogel Microspheres with a Three-Pronged Approach Alleviate Age-Related Osteoarthritis.
Paeoniflorin Alleviates Lipopolysaccharide-Induced Neuroinflammation and Depression Through the Keap1/Nrf2/HO-1 Signaling Pathway.
Phytochemical characterization and pharmacological mechanisms of Huazhuo Sanjie Chubi Decoction in treating gouty arthritis: A multivariant approach.
Baicalin prevents experimental autoimmune uveitis by promoting macrophage polarization balance through inhibiting the HIF-1α signaling pathway.
ISRIB facilitates post-spinal cord injury recovery through attenuation of neuronal apoptosis and modulation of neuroinflammation.
Conductive hyaluronic acid/phytanic acid hydrogel to deliver recombinant human amelogenin for diabetic wound repair.
Acid-Triggered Cascaded Responsive Supramolecular Peptide Alleviates Myocardial Ischemia‒Reperfusion Injury by Restoring Redox Homeostasis and Protecting Mitochondrial Function.
Exploring the active components and potential mechanisms of Zhimu-Huangbai herb-pair in the treatment of depression.
Indole-3-Propionic Acid Attenuates Neuroinflammation and Cognitive Deficits by Inhibiting the RAGE-JAK2-STAT3 Signaling Pathway.
Luteolin modulates liver macrophage subtype polarization and play protective role in sepsis induced acute hepatic injury.
Intranasal Delivery of Hydrophobic AC5216 Loaded Nanoemulsion into Brain To Alleviate Chronic Unpredictable Stress-Induced Depressive-like Behaviors.
Gastrodin Alleviates Lumbar Intervertebral Disc Degeneration by Suppressing the NF-κB and MAPK Pathways.
Activation of GPER1 alleviates white matter injury by promoting microglia M2 polarization through EGFR/Stat3 pathway in intracerebral hemorrhage mice.
Multifunctional injectable hydrogel incorporating EGCG-Cu complexes for synergistic antibacterial, immunomodulatory, and osteogenic therapy in periodontitis.
Macrophage membrane functionalized composite microspheres promote bone regeneration in periodontitis via manipulating inflammation reversing-osteogenesis coupling.
K(+)-H(+) coupling strategy for immune regulation and bone defect repair.
3D bioprinted biomimetic MOF-functionalized hydrogel scaffolds for bone regeneration: Synergistic osteogenesis and osteoimmunomodulation.
Novel pH-responsive lipid nanoparticles deliver UA-mediated mitophagy and ferroptosis for osteoarthritis treatment.
miR-301a-5p regulated IKKβ/NF-κB axis and macrophage polarization to accelerate skin wound healing.
Gallic acid promotes M2 macrophage polarization through mitochondrial oxidative phosphorylation in periodontitis.
TGF-β1 induces autophagy and mediates the effect on macrophages differentiation in primary liver cancer.
Sleep deficiency exacerbates periodontal inflammation via trigeminal TRPV1 neurons.
Tumor-derived exosomal miR-425-5p and miR-135b-3p enhance colorectal cancer progression through immune suppression and vascular permeability promotion.
Direct Peritoneal Resuscitation and Melatonin in the Treatment of Abdominal Sepsis-Induced Lung Injury via Macrophage Metabolic Reprogramming.
GDF11 Regulates M1 and M2 Polarization of BV2 Microglial Cells via p38 MAPK Signaling Pathway.
Human dental follicle cell-derived conditioned media enhance periodontal regeneration by regulating the osteogenic differentiation and inflammation of periodontal ligament stem cells and macrophage polarization.
Unveiling the roles of HIPK2 in atherosclerosis: Insights into the β-catenin/STAT1 signaling cascade and the involvement of SENP1.
Umbilical Cord-Mesenchymal Stromal Cell-Derived Extracellular Vesicles Target the Liver to Improve Neurovascular Health in Type 2 Diabetes With Non-Alcoholic Fatty Liver Disease.
Icariin delivery system based on covalent organic framework materials: dual effects of immune modulation and osteogenesis promotion.
Magnetically Driven Biomimetic Microrobot Loaded with Eleutheroside B for Targeted Delivery and Neural Repair in Spinal Cord Injury.
Rhein Inhibits Microglia-Mediated Neuroinflammation and Neuronal Damage of Alzheimer's Disease via Regulating the Glutamine-Aspartate-Arginine-NO Metabolic Pathway.
Preparation, Characterization, and Functional Evaluation of a Novel Recombinant Hypoglycemic Protein with Multifunctional Effects.
Poldip2 Aggravates inflammation in diabetic retinopathy by impairing mitophagy via the AMPK/ULK1/Pink1 pathway.
Astragalus polysaccharide alleviates mastitis disrupted by Staphylococcus aureus infection by regulating gut microbiota and SCFAs metabolism.
Isosteviol Sodium Promotes Neurological Function Recovery in a Model of Spinal Cord Injury in Rats.
TNFα-reliant FSP1 up-regulation promotes intervertebral disc degeneration via caspase 3-dependent apoptosis.
Zuojin Wan Suppresses the Progression of Colorectal Cancer by Inhibiting M2 Tumor-Associated Macrophages Through JAK2/STAT3 Signaling Pathway and In Vivo and In Vitro.
Cimicifuga heracleifolia kom. Attenuates ulcerative colitis through the PI3K/AKT/NF-κB signaling pathway.
Ginsenoside Rd protects against acute liver injury by regulating the autophagy NLRP3 inflammasome pathway.
TDP43 augments astrocyte inflammatory activity through mtDNA-cGAS-STING axis in NMOSD.
Extracellular Matrix-Mimicking Hydrogel with Angiogenic and Immunomodulatory Properties Accelerates Healing of Diabetic Wounds by Promoting Autophagy.
Nitric Oxide-Releasing Mesoporous Hollow Cerium Oxide Nanozyme-Based Hydrogel Synergizes with Neural Stem Cell for Spinal Cord Injury Repair.
The malic acid inhibiting inflammation in ankylosing spondylitis by interfering M1 macrophage polarization.
CCAAT/Enhancer-Binding Protein Beta Nitration Participates in Hyperhomocysteinemia-Induced Cardiomyocyte Autophagic Flux Blockage by Inhibiting Transcription Factor EB Transcription.
Enhanced hydrogel loading of quercetin-loaded hollow mesoporous cerium dioxide nanoparticles for skin flap survival.
Novel full-thickness biomimetic corneal model for studying pathogenesis and treatment of diabetic keratopathy.
Biomimetic ECM nerve guidance conduit with dynamic 3D interconnected porous network and sustained IGF-1 delivery for enhanced peripheral nerve regeneration and immune modulation.
ZIP8 Regulates Inflammation and Macrophage Polarisation in Intervertebral Disc Degeneration via the Wnt/β-Catenin Pathway.
KAT3B-mediated succinylation of DERL3 suppresses osteogenic differentiation by promoting M1/M2 macrophage polarization.
Pathophysiology-Directed Engineering of a Combination Nanoanalgesic for Neuropathic Pain.
HSPA1A inhibits pyroptosis and neuroinflammation after spinal cord injury via DUSP1 inhibition of the MAPK signaling pathway.
Nasal mucosal mesenchymal stem cells promote repair of sciatic nerve injury in rats by modulating the inflammatory microenvironment.
Blocking the CCL5/CCL7-CCR1 axis regulates macrophage polarization through NF-κB pathway to alleviate the progression of osteoarthritis.
Methanol Extract of Pueraria lobata (Willd.) Root and Its Active Ingredient, Puerarin, Induce Apoptosis in HeLa Cells and Attenuates Bacterial Vaginosis in Gardnerella vaginalis-Infected Mice.
Phillyrin ameliorates DSS-induced colitis in mice via modulating the gut microbiota and inhibiting the NF-κB/MLCK pathway.
Novel HOCl-Responsive Theranostic Prodrug for the Early Diagnosis and Therapy of Ischemic Stroke.
IL-27 regulates macrophage ferroptosis by inhibiting the Nrf2/HO1 signaling pathway in sepsis-induced ARDS.
Cynarin as a potent anti‑osteolytic agent: Targeting MAPK and Nrf2‑Keap1 pathways for osteoclast inhibition and bone protection.
KNC nanozyme repairs hypoxia ischemia brain damage through ALOX12 mediated lipid peroxidation inhibition.
Mesenchymal stem cell-derived small extracellular vesicles-loaded GelMA microspheres enhance diabetic wound healing by promoting M2 macrophage polarization through p38 MAPK inhibition.
Deoxycholic Acid and Lipoteichoic Acid cooperatively drive macrophage M2/M1 polarization via TGR5/STAT3 and TLR2/NF-κB to fuel HCC progression in obesity.
MicroRNA-3473b regulates corticosterone-induced microglial polarization and inflammation through TREM2.
Synovium-On-A-Chip: Simulating the Microenvironment of the Rheumatoid Arthritis Synovium via Multicell Interactions to Target Fibroblast-Like Synoviocytes.
Interfacial Coordination-Engineered Emulgel Modulates the Osteo-Immune Microenvironment in Periodontitis Treatment Via HIF1 Signaling Pathway-Induced Metabolic Reprogramming.
Steroid Receptor Coactivator-1 Drives Tumor-Associated Macrophage Reprogramming by Mediating MMP12 Transcription in Pancreatic Cancer Perineural Invasion.
Microglia-specific interleukin-4 delivery by engineered extracellular vesicles restores inner blood-retinal barrier in diabetic retinopathy via GAS6-MERTK pathway.
Ectomesenchymal Stem Cell Transplantation Induces Microglial Polarization and Anti-inflammatory IL-10 Secretion via NF-κB and MAPK Pathways to Mitigate Brain Injury Post-cerebral Hemorrhage.
Palmatine Attenuates Lipopolysaccharide-Induced Acute Lung Injury Via Suppression of NLRP3 Inflammasome Activation, Pyroptosis, and Metabolic Remodeling.
Genistein ameliorates non-alcoholic fatty liver disease in mice by modulating gut microbiota and hepatic macrophage polarization.
Protective Effects of Arecoline on LPS-Induced Neuroinflammation in BV2 Microglial Cells.
Astragaloside IV improves cognitive impairment in diabetes by inhibiting calpain-1/NLRP3 mediated microglial activation.
tsRNA-10105-enriched migrasomes mediate hepatocellular carcinoma immunosuppressive microenvironment by inducing M2 Macrophage polarization.
Microglial-derived nitric oxide regulates amygdala synaptic plasticity to drive chronic pain and depression induced by lumbar disc herniation.
Irisin Alleviates Autoimmune Uveitis Through Promoting Retinal Microglial M1 to M2 Phenotypic Polarization Mediated by HIF-1α Pathway.
Hyaluronic acid-anchored nanoparticles co-delivering emodin and siRNA confers protection against rheumatoid arthritis via macrophage polarization.
Black phosphorus nanosheets promote neuronal differentiation of neural stem cells through adhesion and pinocytosis for spinal cord injury repair.
Improved prebiotic-based "shield" equipped probiotics for enhanced colon cancer therapy by polarizing M1 macrophages and regulating intestinal microbiota.
Naringenin Accelerates Diabetic Wound Healing via Regulating Macrophage M2 Polarization and Efferocytosis.
Pyroptosis-responsive microspheres modulate the inflammatory microenvironment to retard osteoporosis in female mice.
RBM15 enhances paclitaxel resistance in triple-negative breast cancer by targeting m(6)A methylation of TNFSF9 and inducing polarization of tumor-associated macrophages to M2 phenotype.
Low-Dose, Post-Storage Dancong Tea Attenuates Hydroalcohol-Induced Gastric Damage via Modulation Antioxidant and Anti-Inflammatory Pathways.
Differential expression of lysine-acetylated proteins in the anti-inflammatory effects of luteolin-gadolinium on macrophages.
Vanillic acid ameliorates collagen-induced arthritis by suppressing the inflammation response via inhibition of the MAPK and NF-κB signaling pathways.
CIP2A promotes bronchiolitis obliterans by activating the NF‑κB pathway.
sLithospermic acid etched ZIF-8 nanoparticles delays osteoarthritis progression by inhibiting inflammatory signaling pathways and rescuing mitochondrial damage.
Strontium-based quaternary ammonium salt chitosan particles for ultrafast hemostasis of open fracture.
Systemic Lupus Erythematosus Exacerbates Hip Arthritis by Promoting Chondrocyte Pyroptosis in the Femoral Head via Activating the NF-κB Pathway.
Neutralization of IL-17 and CXCR1 Protects Septic Arthritis by Regulating CXCL8-CXCR1 Pathway Along With Functional Activities in Neutrophils.
ErTao decoction alleviates liver fibrosis by suppressing STING-mediated macrophages and NLRP3 inflammasome activation.
Facile Nanocomposite Hydrogel Scaffold with Sustained Drug Release and Osteo-Immunomodulatory Effects to Enhance Bone Regeneration.
Tannic acid‑cerium nanoenzymes serve as broad-spectrum antioxidants to alleviate acute kidney injury by modulating macrophage polarization, mitophagy and endoplasmic reticulum stress.
Lack of ALCAT1 enhances the protective effects of aerobic exercise on kidney in HFpEF mice.
Echinatin attenuates acute lung injury and inflammatory responses via TAK1-MAPK/NF-κB and Keap1-Nrf2-HO-1 signaling pathways in macrophages.
Rauwolfia polysaccharide can inhibit the progress of ulcerative colitis through NOS2-mediated JAK2/STAT3 pathway.
Artesunate-Nanoliposome-TPP, a Novel Drug Delivery System That Targets the Mitochondria, Attenuates Cisplatin-Induced Acute Kidney Injury by Suppressing Oxidative Stress and Inflammatory Effects.
Myeloid Deletion of Cdc42 Protects Liver From Hepatic Ischemia-Reperfusion Injury via Inhibiting Macrophage-Mediated Inflammation in Mice.
Astragalus Polysaccharide Mitigates Rhabdomyolysis-Induced Acute Kidney Injury via Inhibition of M1 Macrophage Polarization and the cGAS-STING Pathway.
Multifunctionally disordered TiO(2) nanoneedles prevent periprosthetic infection and enhance osteointegration by killing bacteria and modulating the osteoimmune microenvironment.
A tantalum-containing zirconium-based metallic glass with superior endosseous implant relevant properties.
TLR4/TNFR1 blockade suppresses STAT1/STAT3 expression and increases SOCS3 expression in modulation of LPS-induced macrophage responses.
Targeted delivery of berberine using bionic nanomaterials for Atherosclerosis therapy.
Oxysophoridine inhibits oxidative stress and inflammation in hepatic fibrosis via regulating Nrf2 and NF-κB pathways.
Study on the involvement of microglial S100A8 in neuroinflammation and microglia activation during migraine attacks.
Dihydroartemisinin Modulates Enteric Glial Cell Heterogeneity to Alleviate Colitis.
The expansion of MDSCs induced by exosomal PD-L1 promotes the progression of gastric cancer.
Macrophage membrane-camouflaged biomimetic nanoparticles for rheumatoid arthritis treatment via modulating macrophage polarization.
Ocotillol-Type Pseudoginsenoside-F11 Alleviates Lipopolysaccharide-Induced Acute Kidney Injury through Regulation of Macrophage Function by Suppressing the NF-κB/NLRP3/IL-1β Signaling Pathway.
RNF31-mediated IKKα ubiquitination aggravates inflammation and intestinal injury through regulating NF-κB activation in human and mouse neonates.
Aerobic Exercise Protects against Cardiotoxin-Induced Skeletal Muscle Injury in a DDAH1-Dependent Manner.
Suppressed testicular macrophage M1 polarization by HDAC5 enforces insensitivity to LPS-elicited blood-testis barrier damage.
A Janus Microsphere Delivery System Orchestrates Immunomodulation and Osteoinduction by Fine-tuning Release Profiles.
osa-miR168a, a Plant miRNA That Survives the Process of In Vivo Food Digestion, Attenuates Dextran Sulfate Sodium-Induced Colitis in Mice by Oral Administration.
Bakuchiol regulates TLR4/MyD88/NF-κB and Keap1/Nrf2/HO-1 pathways to protect against LPS-induced acute lung injury in vitro and in vivo.
Paeonol interferes with lupus nephritis by regulating M1/M2 polarization of macrophages.
Arylacryl amides: Design, synthesis and the protection against cisplatin-induced acute kidney injury via TLR4/STING/NF-κB pathway.
N6-Methyladenosine Modification of lncCCKAR-5 Regulates Autophagy in Human Umbilical Cord Mesenchymal Stem Cells by Destabilizing LMNA and Inhibits Diabetic Wound Healing.
CD163+ macrophage density in perimysial connective tissue associated with prognosis in IMNM.
YY1 Lactylation Aggravates Autoimmune Uveitis by Enhancing Microglial Functions via Inflammatory Genes.
Unmasking the dynamics of Mycoplasma gallisepticum: deciphering HD11 macrophage polarization for innovative infection control strategies.
Genkwanin alleviates intervertebral disc degeneration via regulating ITGA2/PI3K/AKT pathway and inhibiting apoptosis and senescence.
Hypoxia-induced TREM1 promotes mesenchymal-like states of glioma stem cells via alternatively activating tumor-associated macrophages.
The Therapeutic Effects of Baicalein on the Hepatopulmonary Syndrome in the Rat Model of Chronic Common Bile Duct Ligation.
MicroRNA-142-3p alleviated high salt-induced cardiac fibrosis via downregulating optineurin-mediated mitophagy.
Spinster homolog 2 reduces malignancies of glioblastoma via PTEN/PI3K/AKT pathway.
Htr2b Promotes M1 Microglia Polarization and Neuroinflammation after Spinal Cord Injury via Inhibition of Neuregulin-1/ErbB Signaling.
Photothermal and Photocatalytic Glycol Chitosan and Polydopamine-Grafted Oxygen Vacancy Bismuth Oxyiodide (BiO(1-x) I) Nanoparticles for the Diagnosis and Targeted Therapy of Diabetic Wounds.
Inhibition of SAT1 alleviates chondrocyte inflammation and ferroptosis by repressing ALOX15 expression and activating the Nrf2 pathway.
Tibial cortex transverse transport promotes ischemic diabetic foot ulcer healing via enhanced angiogenesis and inflammation modulation in a novel rat model.
Pentraxin 3 exacerbates psoriasiform dermatitis through regulation of macrophage polarization.
Roseburia intestinalis sensitizes colorectal cancer to radiotherapy through the butyrate/OR51E1/RALB axis.
Peroxiredoxin 3 has a crucial role in the macrophage polarization by regulating mitochondrial homeostasis.
Protective effect of Tao Hong Si Wu Decoction against inflammatory injury caused by intestinal flora disorders in an ischemic stroke mouse model.
Independent prognostic value of CLDN6 in bladder cancer based on M2 macrophages related signature.
Corydalis tomentella Franch. Exerts anti-inflammatory and analgesic effects by regulating the calcium signaling pathway.
Wogonin alleviates sepsis-induced acute lung injury by modulating macrophage polarization through the SIRT1-FOXO1 pathways.
Targeted Repair of Spinal Cord Injury Based on miRNA-124-3p-Loaded Mesoporous Silica Camouflaged by Stem Cell Membrane Modified with Rabies Virus Glycoprotein.
COL8A1 is a potential prognostic biomarker associated with migration, proliferation, and tumor microenvironment in glioma.
Absence of PD-L1 signaling hinders macrophage defense against Mycobacterium tuberculosis via upregulating STAT3/IL-6 pathway.
Icariside II modulates pulmonary fibrosis via PI3K/Akt/β-catenin pathway inhibition of M2 macrophage program.
Comprehensive molecular characterization of long-term glioblastoma survivors.
Small Extracellular Vesicles Derived from Altered Peptide Ligand-Loaded Dendritic Cell Act as A Therapeutic Vaccine for Spinal Cord Injury Through Eliciting CD4(+) T cell-Mediated Neuroprotective Immunity.
Intermittent mild cold stimulation alleviates cold stress-induced pulmonary fibrosis by inhibiting the TGF-β1/Smad signaling pathway in broilers.
iNOS inhibitor S-methylisothiourea alleviates smoke inhalation-induced acute lung injury by suppressing inflammation and macrophage infiltration.
COL6A3 enhances the osteogenic differentiation potential of BMSCs by promoting mitophagy in the osteoporotic microenvironment.
Epigenetic modification of TWIST1 in macrophages promotes hypertension-induced atherosclerotic plaque instability.
Edaravone dexborneol alleviates cerebral ischemia-reperfusion injury through NF-κB/NLRP3 signal pathway.
Multi-Omics Profiling Identifies Microglial Annexin A2 as a Key Mediator of NF-κB Pro-inflammatory Signaling in Ischemic Reperfusion Injury.
Troxerutin dampened hypothalamic neuroinflammation via microglial IL-22/IL-22R1/IRF3 activation in dihydrotestosterone-induced polycystic ovary syndrome rats.
FAM76B regulates PI3K/Akt/NF-κB-mediated M1 macrophage polarization by influencing the stability of PIK3CD mRNA.
Integrated-omics profiling unveils the disparities of host defense to ECM scaffolds during wound healing in aged individuals.
A Novel Compound Ligusticum Cycloprolactam Alleviates Neuroinflammation After Ischemic Stroke via the FPR1/NLRP3 Signaling Axis.
Single-cell RNA sequencing reveals the intercellular crosstalk and the regulatory landscape of stromal cells during the whole life of the mouse ovary.
The plant extract PNS mitigates atherosclerosis via promoting Nrf2-mediated inhibition of ferroptosis through reducing USP2-mediated Keap1 deubiquitination.
Inosine Prevents Colorectal Cancer Progression by Inducing M1 Phenotypic Polarization of Macrophages.
The PD-1 /PD-L1 signaling pathway regulates decidual macrophage polarization and may participate in preeclampsia.
Mechanically induced M2 macrophages are involved in bone remodeling of the midpalatal suture during palatal expansion.
Effect of Scaffold Geometrical Structure on Macrophage Polarization during Bone Regeneration Using Honeycomb Tricalcium Phosphate.
Inhibiting PRMT1 protects against CoNV by regulating macrophages through the FGF2/PI3K/Akt pathway.
S100A9, as a potential predictor of prognosis and immunotherapy response for GBM, promotes the malignant progression of GBM cells and migration of M2 macrophages.
Modulation of secretory factors by lipofundin contributes to its anti‑neuroinflammatory effects.
Phenolics and terpenoids with good anti-inflammatory activity from the fruits of Amomum villosum and the anti-inflammatory mechanism of active diterpene.
Dehydroandrographolide facilitates M2 macrophage polarization by downregulating DUSP3 to inhibit sepsis-associated acute kidney injury.
Pyxinol Fatty Acid Ester Derivatives J16 against AKI by Selectively Promoting M1 Transition to M2c Macrophages.
Multiscale architecture design of 3D printed biodegradable Zn-based porous scaffolds for immunomodulatory osteogenesis.
Adhesive hydrogel releases protocatechualdehyde-Fe(3+) complex to promote three healing stages for accelerated therapy of oral ulcers.
Strontium Ranelate Ameliorates Intervertebral Disc Degeneration via Regulating TGF-β1/NF-κB Axis.
Shikimic acid (SA) inhibits neuro-inflammation and exerts neuroprotective effects in an LPS-induced in vitro and in vivo model.
The role of the SGK3/TOPK signaling pathway in the transition from acute kidney injury to chronic kidney disease.
Jianpi Yangzheng Xiaozheng decoction alleviates gastric cancer progression via suppressing exosomal PD-L1.
Ethyl-acetate fraction from a cinnamon-cortex extract protects pancreatic β-cells from oxidative stress damage.
TSAb Modulates Microglia M1 Polarization via Activation of the TSHR-Mediated NF-κB Signaling Pathway.
BMP7 Attenuates Neuroinflammation after Spinal Cord Injury by Suppressing the Microglia Activation and Inducing Microglial Polarization Via the STAT3 Pathway.
CD73 inhibits titanium particle-associated aseptic loosening by alternating activation of macrophages.
DDAH1 Protects against Cardiotoxin-Induced Muscle Injury and Regeneration.
ASIC1a-CMPK2-mediated M1 macrophage polarization exacerbates chondrocyte senescence in osteoarthritis through IL-18.
Chromofungin, a chromogranin A-derived peptide, protects against sepsis-induced acute lung injury by inhibiting LBP/TLR4-dependent inflammatory signaling.
Hesperidin mitigates oxidative stress-induced ferroptosis in nucleus pulposus cells via Nrf2/NF-κB axis to protect intervertebral disc from degeneration.
Epsin1-mediated exosomal sorting of Dll4 modulates the tubular-macrophage crosstalk in diabetic nephropathy.
Expression pattern analysis of m6A regulators reveals IGF2BP3 as a key modulator in osteoarthritis synovial macrophages.
Ergosterol Isolated from Antrodia camphorata Suppresses LPS-Induced Neuroinflammatory Responses in Microglia Cells and ICR Mice.
Long-Term Immunogenicity and In Vitro Prophylactic Protective Efficacy of M. tuberculosis Fusion Protein DR2 Combined with Liposomal Adjuvant DIMQ as a Boosting Vaccine for BCG.
Atrazine induces phagocytotic dysfunction of microglia depends on nucleocytoplasmic translocation of acetylated HMGB1.
MAGL regulates synovial macrophage polarization vis inhibition of mitophagy in osteoarthritic pain.
Ent-kauranes and ent-atisanes from Euphorbia wallichii and their anti-inflammatory activity.
Disturbance of neuron-microglia crosstalk mediated by GRP78 in Neuropsychiatric systemic lupus erythematosus mice.
NLRP3 activation in microglia contributes to learning and memory impairment induced by chronic lead exposure in mice.
Macrophages contribute to periodontal wound healing mainly in the tissue proliferation stage.
MiR-29c Inhibits TNF-α-Induced ROS Production and Apoptosis in Mouse Hippocampal HT22 Cell Line.
Cyasterone inhibits IL-1β-mediated apoptosis and inflammation via the NF-κB and MAPK signaling pathways in rat chondrocytes and ameliorates osteoarthritisin vivo.
FNDC5/Irisin Inhibits the Inflammatory Response and Mediates the Aerobic Exercise-Induced Improvement of Liver Injury after Myocardial Infarction.
CXCL chemokines-mediated communication between macrophages and BMSCs on titanium surface promotes osteogenesis via the actin cytoskeleton pathway.
Quercetin improves cerebral ischemia/reperfusion injury by promoting microglia/macrophages M2 polarization via regulating PI3K/Akt/NF-κB signaling pathway.
Red Cabbage Juice-Mediated Gut Microbiota Modulation Improves Intestinal Epithelial Homeostasis and Ameliorates Colitis.
Inducible nitric oxide synthase (iNOS)-activated Cxcr2 signaling in myeloid cells promotes TGFβ-dependent squamous cell carcinoma lung metastasis.
Red cabbage juice-mediated gut microbiota modulation improves intestinal epithelial homeostasis and ameliorates colitis.
Injectable photocrosslinking spherical hydrogel-encapsulated targeting peptide-modified engineered exosomes for osteoarthritis therapy.
Irisin attenuates acute lung injury by suppressing the pyroptosis of alveolar macrophages.
Wei-Tong-Xin exerts anti-inflammatory effects through TLR4-mediated macrophages M1/M2 polarization and affects GLP-1 secretion.
Glucose Transporter Glut1-Dependent Metabolic Reprogramming Regulates Lipopolysaccharide-Induced Inflammation in RAW264.7 Macrophages.
Synthesis of Lathyrol PROTACs and Evaluation of Their Anti-Inflammatory Activities.
Concentrated growth factor combined with iRoot BP Plus promotes inflamed pulp repair: an in vitro and in vivo study.
Betaine Inhibits NLRP3 Inflammasome Hyperactivation and Regulates Microglial M1/M2 Phenotypic Differentiation, Thereby Attenuating Lipopolysaccharide-Induced Depression-Like Behavior.
Comparison of Three Species of Rhubarb in Inhibiting Vascular Endothelial Injury via Regulation of PI3K/AKT/NF-κB Signaling Pathway.
Inhibiting Sphingosine 1-Phosphate Receptor Subtype 3 Attenuates Brain Damage During Ischemia-Reperfusion Injury by Regulating nNOS/NO and Oxidative Stress.
Novel recombinant protein flagellin A N/C attenuates experimental autoimmune encephalomyelitis by suppressing the ROS/NF-κB/NLRP3 signaling pathway.
Single-cell RNA sequencing reveals distinct immunology profiles in human keloid.
Cassane diterpenoid ameliorates dextran sulfate sodium-induced experimental colitis by regulating gut microbiota and suppressing tryptophan metabolism.
Isoalantolactone (IAL) Regulates Neuro-Inflammation and Neuronal Apoptosis to Curb Pathology of Parkinson's Disease.
Macrophage-derived extracellular vesicles regulate follicular activation and improve ovarian function in old mice by modulating local environment.
Eupalinolide B attenuates lipopolysaccharide-induced acute lung injury through inhibition of NF-κB and MAPKs signaling by targeting TAK1 protein.
Fecal microbiota transplantation from young donor mice improves ovarian function in aged mice.
Extracellular vesicles from human urine-derived stem cells merged in hyaluronic acid ameliorate erectile dysfunction in type 2 diabetic rats by glans administration.
Oxybaphus himalaicus Mitigates Lipopolysaccharide-Induced Acute Kidney Injury by Inhibiting TLR4/MD2 Complex Formation.
Galectin-3 regulates microglial activation and promotes inflammation through TLR4/MyD88/NF-kB in experimental autoimmune uveitis.
The circadian clock protein Rev-erbα provides neuroprotection and attenuates neuroinflammation against Parkinson's disease via the microglial NLRP3 inflammasome.
Apelin alleviated neuroinflammation and promoted endogenous neural stem cell proliferation and differentiation after spinal cord injury in rats.
Salubrinal protects against inflammatory response in macrophage and attenuates psoriasiform skin inflammation by antagonizing NF-κB signaling pathway.
Tamoxifen Exerts Anticancer Effects on Pituitary Adenoma Progression via Inducing Cell Apoptosis and Inhibiting Cell Migration.
Glabridin inhibits liver fibrosis and hepatic stellate cells activation through suppression of inflammation and oxidative stress by activating PPARγ in carbon tetrachloride-treated mice.
Epoxymicheliolide prevents dextran sulfate sodium-induced colitis in mice by inhibiting TAK1-NF-κB pathway and activating Keap1-NRF2 signaling in macrophages.
Burdock (Arctium lappa L.) leaf flavonoids rich in morin and quercetin 3-O-rhamnoside ameliorate lipopolysaccharide-induced inflammation and oxidative stress in RAW264.7 cells.
The licorice flavonoid isoliquiritigenin attenuates Mycobacterium tuberculosis-induced inflammation through Notch1/NF-κB and MAPK signaling pathways.
The alleviative effect of flavonol-type Nrf2 activator rhamnazin from Physalis alkekengi L. var. franchetii (Mast.) Makino on pulmonary disorders.
Limonin Inhibits IL-1β-Induced Inflammation and Catabolism in Chondrocytes and Ameliorates Osteoarthritis by Activating Nrf2.
Targeting Myadm to Intervene Pulmonary Hypertension on Rats Before Pregnancy Alleviates the Effect on Their Offspring's Cardiac-Cerebral Systems.
Spinal Nrf2 translocation may inhibit neuronal NF-κB activation and alleviate allodynia in a rat model of bone cancer pain.
Sulforaphane alleviates hyperalgesia and enhances analgesic potency of morphine in rats with cancer-induced bone pain.
Proto-oncogene tyrosine-protein kinase SRC (Src) inhibition in microglia relieves neuroinflammation in neuropathic pain mouse models.
CGRP-Mediated Prolactin Upregulation: a Possible Pathomechanism in IgG4-Related Disease.
Weak Ultraviolet B Enhances the Mislocalization of Claudin-1 Mediated by Nitric Oxide and Peroxynitrite Production in Human Keratinocyte-Derived HaCaT Cells.
Protective effects and potential mechanism of salvianolic acid B on sodium laurate-induced thromboangiitis obliterans in rats.
Geniposide attenuates Aβ(25-35)-induced neurotoxicity via the TLR4/NF-κB pathway in HT22 cells.
Tan Y, Xia J, Liu M, Deng S, Wu H, Qian C
Mediators of inflammation 2026;2026:5595023
Mediators of inflammation 2026;2026:5595023
Platelet-rich plasma-derived microRNA let-7a-5p alleviates knee osteoarthritis by regulating macrophage polarization and improving inflammatory microenvironment.
Li Q, Wang M, Wang D, Nie Y, Sun X, Na L, Yan D, Ma Y, Wang H
Frontiers in immunology 2026;17:1756467
Frontiers in immunology 2026;17:1756467
Meningeal lymphatic vessel dysfunction exacerbates brain injury in CVST mice via endoplasmic reticulum and oxidative stress pathways.
Ying J, Li J, Wu X, Chen X, Zhang H, Wei L, Jing J, Wang S
Frontiers in immunology 2026;17:1745066
Frontiers in immunology 2026;17:1745066
A near-infrared regulated programmable multi-mode periosteum scaffold for sequential healing of infected bone defects.
Yin Y, Cai Y, Dang P, Zeng W, Wang L, Yan X, Luo Z, Liu W, Zhu Y, Chen L, Zhang C
Bioactive materials 2026 Sep;63:56-72
Bioactive materials 2026 Sep;63:56-72
Stromal cell-derived itaconate promotes endometriosis via macrophage NRF2 and lysosomal pH modulation.
Zhong Z, Wang S, Ren Q, Jiao X, Xu L, Dong X, Li N, Guan H, Chu R, Yuan M, Liu J, Du Y, Wei K, Yan L, Wang G
Redox biology 2026 May;92:104101
Redox biology 2026 May;92:104101
Histone H3K9 lactylation activates the TXNIP/NLRP3 pathway to drive macrophage inflammation after spinal cord injury.
Shi C, Yuan F, Chen X, Xu S, Ding Y, Wen H, Duan C, Wu T, Lu H, Hu J, Xu J, Jiang L
Redox biology 2026 May;92:104078
Redox biology 2026 May;92:104078
Antimicrobial peptide chensinin-1b attenuates T2DM progression in atherosclerotic ApoE(-/-) mice.
Qiu Z, Fan F, Li Z, Sun Y, Shang D
Diabetic medicine : a journal of the British Diabetic Association 2026 May;43(5):e70232
Diabetic medicine : a journal of the British Diabetic Association 2026 May;43(5):e70232
Partial NaCl replacement with arginine during brining influences apoptosis and post-brining quality of grass carp fillets.
Xiong X, Li Q, Dou P, Huang T, Zhuang S, Tan Y, Ma H, Hong H, Luo Y
Food chemistry 2026 May 30;512:148995
Food chemistry 2026 May 30;512:148995
Self-Assembled Quercetin-Mecobalamin Nanoparticles Mitigate Ischemic Stroke Injury via Enhanced Neuroprotection and Microglial Modulation.
Zhang T, Fan S, Ji H, Liu W, Chen X, Fu D
ACS biomaterials science & engineering 2026 May 11;12(5):2606-2618
ACS biomaterials science & engineering 2026 May 11;12(5):2606-2618
Integrative epidemiology and multi-omics reveal a frailty-associated ACKR1 redox axis linking cadmium exposure to atherosclerosis.
Zhang K, Han J, Chen P, Li H, Wu Y, Shi Y, Hou B, Weng W, Wang Y, Zhu Z
Redox biology 2026 Mar;90:104048
Redox biology 2026 Mar;90:104048
Modification of 3D printed porous titanium implants with on-demand delivery of curcumin and stromal cell derived factor-1 for osseointegration improvement.
Ning R, Tang J, Chen L
International journal of biological macromolecules 2026 Mar;350:151037
International journal of biological macromolecules 2026 Mar;350:151037
Dynamic ROS-responsive hyperbranched polymer-based neuroprotective drug delivery system for pathogenesis-adaptive sequential therapy of cerebral ischemic stroke.
Ma X, Zhang X, Wang Y, Xu Y, Liu L, Li W, Ren X, He Z
Biomaterials 2026 Mar;326:123683
Biomaterials 2026 Mar;326:123683
Modulation of immune cell differentiation by Prunella vulgaris L. essential oil in pulmonary sarcoidosis treatment.
Mao Z, Yang X, Liu Y, Huan Y, Gao Y, Zhang J, Lin X, Tian S, Song Y, Miao M
Fitoterapia 2026 Mar;189:107049
Fitoterapia 2026 Mar;189:107049
Imperatorin ameliorates metabolic dysfunction-associated fatty liver disease through modulating Suv39h1/Fabps/Cept1 signalling pathway.
Sun Y, Wang C, Wang Y, Hao R, Liu L, Jin Y, Sun H
British journal of pharmacology 2026 Mar;183(5):1104-1121
British journal of pharmacology 2026 Mar;183(5):1104-1121
Dextrorotatory kynurenine suppresses acute rejection through inhibiting M1 macrophage-mediated inflammation.
Zhao Y, Wu J, Li Y, Cao Y, Zhu T, Guo Y, Yang C, Zhu D
EMBO molecular medicine 2026 Mar;18(3):979-1008
EMBO molecular medicine 2026 Mar;18(3):979-1008
Nature-inspired confined cascade enzyme nanoreactors for targeted atherosclerosis therapy.
Wu Y, Xia H, Ding H, Long M, Yan S, Zhang M, Sheng J, Gu N
Signal transduction and targeted therapy 2026 Mar 9;11(1)
Signal transduction and targeted therapy 2026 Mar 9;11(1)
Curcumin protects against difenoconazole-induced kidney injury in carp by inhibiting ferroptosis through the Nrf2/GPX4 axis.
Zhang S, Li X, Gao Y, Dong Q, Jin X, Shi P, Dong J
Fish physiology and biochemistry 2026 Mar 5;52(2)
Fish physiology and biochemistry 2026 Mar 5;52(2)
ZXDB Drives Macrophage Inflammatory Programming in Sepsis-Induced Acute Kidney Injury by Recruiting EIF4A3 to Enhance ACACA Translation.
Wu H, Gang W, Wang L, Sun J, Li S, Guo Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Mar 31;40(6):e71657
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Mar 31;40(6):e71657
Nanocolloidal Hydrogel Coatings With Multiple Functions for Antithrombogenic Biointerfaces.
Ding T, Ren C, Meng L, Zhang X, Shi H, Yang B, Li Y
Advanced healthcare materials 2026 Mar 26;:e04424
Advanced healthcare materials 2026 Mar 26;:e04424
3'-Hydroxypterostilbene Alleviates Obesity and Lipoprotein Metabolism Dysregulation by Reshaping Gut Microbiota in High-Fat Diet-Induced Obese Mice.
Yeh YT, Shih YY, Huang CH, Tsai PL, Chen YK, Ho CT, Tsai HY
Journal of agricultural and food chemistry 2026 Mar 25;74(11):9307-9319
Journal of agricultural and food chemistry 2026 Mar 25;74(11):9307-9319
Single-Atom Nanozyme Driven Lactate Reversal Fuels Oxidative Metabolism and Represses Lactylation to Heal Diabetic Wounds.
Wu W, Zhou H, Zhang M, Zhang X, Huang M, Tao S, Du W, Wang S, Zhao J, Zhou X, Liu N, Chen T
ACS nano 2026 Mar 17;20(10):8548-8569
ACS nano 2026 Mar 17;20(10):8548-8569
Microglial GLUL loss worsens TBI outcomes by amplifying the arginine-citrulline pathway.
Li J, Zhao Y, Yang Y, Dai Q, Tian R, Wang J, Ye J, Zhang L, Li L
Biochimica et biophysica acta. Molecular basis of disease 2026 Jun;1872(5):168230
Biochimica et biophysica acta. Molecular basis of disease 2026 Jun;1872(5):168230
PRMT1 regulates glioblastoma stemness and immunosuppression via nitric oxide metabolism: Multi-cohort analysis and experimental validation.
Xue K, Gao Y, Ma C, Tang S, Tian X, Kong Y, Wang H
Nitric oxide : biology and chemistry 2026 Jun;162:9-24
Nitric oxide : biology and chemistry 2026 Jun;162:9-24
TRPM7 inhibition alleviates acute gouty arthritis in mice by suppressing M1 polarization through the EDN1/EDNRB axis.
Wu S, Zhang Y, Jiang C, Zhang Y, Yu P, Zhao W, Wang Z, Chen Y, Cheng Y, Ding J, Xu Y, Zhao Y, Zhou R, Hu W
International immunopharmacology 2026 Jun 15;179:116624
International immunopharmacology 2026 Jun 15;179:116624
YAP in synovial macrophages mitigates mechanically-induced osteoarthritis by preserving mitochondrial fusion.
Cheng Y, Guo ZL, Gu YF, Li WL, Zhang WB
Cellular signalling 2026 Jul;143:112430
Cellular signalling 2026 Jul;143:112430
Discovery of novel HDAC6 inhibitors based on the diphenyl-1,2,4-oxadiazole scaffold with potential efficacy in alleviating inflammation- and chemotherapy- associated mechanical hypersensitivity.
Yin L, Yin M, Fan Z, Shi Y, Shan J, Wang L, Chen Y, Hao C, Zhuang T, Liu T, Cao X
Bioorganic chemistry 2026 Jul 5;175:109785
Bioorganic chemistry 2026 Jul 5;175:109785
Methyl 3-chloroasterric acid exerted anti-neuroinflammatory and antidepressant effects through the downregulation of P2Y1R.
Zhang Y, Sun M, Zhang Z, Jia Y, Xiao H, Xu X, Pan X, Li Z
International immunopharmacology 2026 Jul 15;181:116689
International immunopharmacology 2026 Jul 15;181:116689
Deficiency of Med1 in keratinocytes augments dermal fibrosis and inflammation in scleroderma.
Luo J, Kang Y, Zhang Z, Zhang E, Huang J, Zhu Q, Guo Q, Song S, Wang B, Li M, Yuan Q, Li H, Zhao D, Chen H, Wang S, Li Y, Zhang B, He J, Hu L
International immunopharmacology 2026 Jul 15;181:116667
International immunopharmacology 2026 Jul 15;181:116667
Overexpression of mitofusin 2 ameliorates inflammation and oxidative stress in lipopolysaccharide-induced mastitis model by regulating phosphofurin acidic cluster sorting protein 2.
Zhou X, Zhang Y, Ma H, Fu S, Liu J, Guo W, Tian X, Huang B
Animal models and experimental medicine 2026 Jan;9(1):154-167
Animal models and experimental medicine 2026 Jan;9(1):154-167
CMTM6 promotes synovial proliferation and macrophage polarization by preventing ubiquitination of TAK1 in rheumatoid arthritis.
Luo X, Xu L, Cai J, Ma S, Song H, Yang P, Yang C
Journal of orthopaedic translation 2026 Jan;56:101005
Journal of orthopaedic translation 2026 Jan;56:101005
Diallyl Trisulfide Suppresses Tumor-Associated Macrophage M2-Like Polarization and Recruitment and Improves the Tumor Microenvironment Through Blocking CCL5/STAT3 Signaling Pathway Against Lung Cancer.
Xie C, Yin J, Zhu J
Phytotherapy research : PTR 2026 Jan;40(1):318-333
Phytotherapy research : PTR 2026 Jan;40(1):318-333
Immunomodulatory mesoporous bioactive glass/interleukin-4 nanocomplex promotes bone regeneration.
Wang N, Chen Y, Cai Y, Liao L, Wang J, Wei J
International journal of biological macromolecules 2026 Jan;339(Pt 1):149869
International journal of biological macromolecules 2026 Jan;339(Pt 1):149869
Daucosterol ameliorates acute inflammation and fibrosis following myocardial infarction via regulation of the ZBTB16 protein.
Sheng S, Wu P, Wu C, Su H, Guo Z, Wang R, Li J, Duan Y, Zhang S, Ma L
British journal of pharmacology 2026 Jan;183(2):313-332
British journal of pharmacology 2026 Jan;183(2):313-332
Pharmacological inhibition of PGK1 by genipin reduces inflammation and oxidative damage in osteoarthritis.
Li M, Peng Y, Xiao Q, Chen S, Zhang C, Chen H, Zhao Y, Chang S, Qiu L, Zhang L, Guo X, Fu Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jan;150:157729
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jan;150:157729
Therapeutic potential of hydroxytyrosol against bisphenol S-induced toxicity to microglia via targeting cytochrome P450 1A1 (CYP1A1).
Zhang H, Lin G, Wang Y, Zheng A, Luo H, Cao Z, Hou G, Hou Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jan;150:157629
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jan;150:157629
Nanogel Integrated Zwitterionic Injectable Hydrogel with Sequential Drug-Releasing Capability for the Programmable Repair of Spinal Cord Injury.
Wei Z, Huang S, Zhang W, Wen J, Zhou X, He W, Yang X, Wang H, Zhai G, Shi B, Jin L, Wang D, Feng S, Ye L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(6):e10976
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(6):e10976
Multimodal hybrid nanozymes with antioxidant catalytic and antibiotic-free antibacterial activities for enhanced multi-target sepsis therapy.
Zhu K, Zhang B, Li Y, Pan Y, Zhang S, Tang H, Yang Z, Tang X, Zhang X, Chen W, Wang Q, Ma S, Zhao L, Yao Y, Zhou H, Chen G
Cell reports. Medicine 2026 Jan 20;7(1):102541
Cell reports. Medicine 2026 Jan 20;7(1):102541
Caveolin-2 Knockdown Alleviated Sepsis-induced Acute Lung Injury Via Promoting Macrophage M2 Polarization and Inhibiting Apoptosis by Hippo Signaling Pathway.
Xue X, Gao F, Chen J, Wang M, Wu X, Liao H, Sun Z, Nie S
Inflammation 2026 Jan 19;49(1):66
Inflammation 2026 Jan 19;49(1):66
A Novel YTHDF2/SIGMAR1 Axis in Astrocytes Regulates Neuroinflammation and Cognitive Impairment in Diabetic Encephalopathy.
Xu F, Zhang H, Chen X, Duan C, Gu Q, Hu J
Inflammation 2026 Jan 16;49(1):55
Inflammation 2026 Jan 16;49(1):55
Narciclasine Alleviates Endothelial Inflammation and Atherosclerosis Initiation by Inhibiting Histone Lactylation-Mediated NF-κB Activation.
Wang Z, Zhang Z, Xin R, Ma M, Sun Z, Li Z, Zhang C, Liu L, Wu Z, Zhang Y, Chen Y
Inflammation 2026 Jan 16;49(1):49
Inflammation 2026 Jan 16;49(1):49
Explore the chemical components of Angong Niuhuang Pill and its potential mechanisms for fever treatment based on UHPLC-Q-Exactive orbitrap HRMS, transcriptomics, and experiment verification.
Gao F, An J, Jia S, Zhu Z, Zhang Z, Li Y, Jiao J, Li S, Liu Y, Yin H, Xu B, Lei H
Journal of ethnopharmacology 2026 Jan 10;354:120542
Journal of ethnopharmacology 2026 Jan 10;354:120542
Mechanistic insights into the effects of Norisoboldine on intestinal immunity and neuroinflammation in a mouse model of slow transit constipation with depression.
Wu B, Wu J, Bai X, Zhou Q, Wang X
Journal of ethnopharmacology 2026 Jan 10;354:120479
Journal of ethnopharmacology 2026 Jan 10;354:120479
Baicalin inhibits bladder cancer progression by suppressing PD-L1-mediated M2 macrophage polarization via ALDH2.
Qiang Z, Ren C, Xie W, Yang Z, Li L, Chen G
Biochemical and biophysical research communications 2026 Jan 1;794:153036
Biochemical and biophysical research communications 2026 Jan 1;794:153036
Genistein Ameliorates the Ischemic State of Random Skin Flap by Regulating Macrophage Polarization Through AMPK/SIRT1 Signaling Pathway.
Fu Y, Ye C, Zhu Y, Chen T, Li Z, Chen Y
Phytotherapy research : PTR 2026 Feb;40(2):420-435
Phytotherapy research : PTR 2026 Feb;40(2):420-435
TWEAK exacerbates allergic conjunctivitis via PKM2-dependent NF-κB activation and macrophage M1 polarization.
Yang Y, Zhang Y, Fu J, Yin X
Cellular signalling 2026 Feb;138:112264
Cellular signalling 2026 Feb;138:112264
Treadmill running modulates infrapatellar fat pad remodeling in osteoarthritic rats in an intensity-dependent manner.
Chen Z, Li G, Deng H, Hu Z, Wang Q, He Z
BMC sports science, medicine & rehabilitation 2026 Feb 5;18(1)
BMC sports science, medicine & rehabilitation 2026 Feb 5;18(1)
Cepharanthine alleviated chronic prostatitis/chronic pelvic pain syndrome by activating Nrf2 and inhibiting the NF-κB pathway.
Zhang H, Zhang D, Wang Z, Liu K, Xu C, Sun H, Yan Z, Li C, Lu B, Yin Y, Zhao C, Niu Y, Li W
Biology direct 2026 Feb 26;21(1)
Biology direct 2026 Feb 26;21(1)
[Isovitexin alleviates myocardial oxidative stress injury in diabetic mice by enhancing myocardial SIRT3 expression and reducing oxidative stress].
Peng Y, Jiang Y, Ma D, He A, Lü D, Luo M, Luo S
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2026 Feb 20;46(2):316-324
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2026 Feb 20;46(2):316-324
Ly93 Inhibits Sphingomyelin Synthesis and Attenuates Inflammation and Injury in Dry Eye Conjunctival Organoids.
Chen Q, Wei Y, Wang L, Liang J, Pang J, Han Y, Qudsi AI, Liang Q
Investigative ophthalmology & visual science 2026 Feb 2;67(2):58
Investigative ophthalmology & visual science 2026 Feb 2;67(2):58
Tet2 deficiency-induced expansion of monocyte-derived macrophages promotes liver fibrosis.
Feng J, Wu B, Li Y, Sun P, Liu Q, Xiao Q, Cai JB, Zheng Y, Chen H, Xu Y, Liu Y, Shi GM, Tan L, Shi YG
The Journal of experimental medicine 2026 Feb 2;223(2)
The Journal of experimental medicine 2026 Feb 2;223(2)
Hypoxia-preconditioned cardiomyocyte-derived extracellular vesicles alleviate myocardial ischemic injury by reprogramming macrophage polarization via the Fgl2/NF-κB pathway.
Zhang Z, Shen H, Zhang S, Zhou J, Zhang M, Wang Y, Zheng Y, Chang Y, Liang X, Hu X, Gao W
International immunopharmacology 2026 Feb 1;170:116077
International immunopharmacology 2026 Feb 1;170:116077
Immunomodulatory effects of biodegradable Mg-Cu-Zn alloy in esophageal cancer.
Chen L, Liao S, Wu X, Lai K, Lu Y, Wang X, Zheng X, Zhang Y, Chen H, Wang Q, Nie JF, Zhou Z
Bioactive materials 2026 Aug;62:294-318
Bioactive materials 2026 Aug;62:294-318
Unravelling the potential of Vitex negundo leaf extract in LPS-induced acute lung injury in mice through modulation of the TLR-4/NF-κB p65/iNOS pathway: Insights from integrated phytochemical characterization, in silico, and in vivo analysis.
Meena M, Sharma M, S I, Mishra AM, Sharma A, V A A, Lingaraju MC, Parida S, Singh V, Chandra V, Singh M, Shanker K, Panwar J, Singh TU
Tissue & cell 2026 Aug;101:103470
Tissue & cell 2026 Aug;101:103470
Tussilagone attenuated cigarette smoke-induced chronic obstructive pulmonary disease through regulating Nrf2 and NF-κB/NLRP3 inflammasome via directly targeting cysteine 434 of KEAP1.
Xu LT, Han QT, Xu ZP, Wang XN, Zhang H, Shen T
Journal of advanced research 2026 Apr;82:1149-1162
Journal of advanced research 2026 Apr;82:1149-1162
Injectable microgels carrying engineered biomimetic nanoparticles for osteoarthritis therapy via dual-targeted senescent chondrocyte clearance and endogenous repair promotion.
Wang P, Zhao H, Zhang S, Guo Y, Xing X, Zhou S, Yang S, Wang F, Chen W, Wang J, Zhang Y
Bioactive materials 2026 Apr;58:486-504
Bioactive materials 2026 Apr;58:486-504
Ultrasound-activated piezoelectric Silk-PVDF hydrogel reprograms the osteoimmune microenvironment via NRF2 signaling for accelerated bone regeneration.
Mo G, Qing L, Zhang C, Huang L, Yan H, Lu S, Zhang Y, Chen W, Xiang X, Wang N, Han G, Li Y, Jiang L, Zhang J
Materials today. Bio 2026 Apr;37:102779
Materials today. Bio 2026 Apr;37:102779
Polyhedral oligomeric silsesquioxane-functionalized carboxymethyl chitin microspheres via irradiation-induced grafting for hemostasis and tissue repair in post-extraction sockets.
Zhao XY, Lei S, Yan M, Jiang X, Zhang YJ, Liu J, Yang MX, Li LG, Wang CY, Xie C, Li TF, Leng F
International journal of biological macromolecules 2026 Apr;358:151727
International journal of biological macromolecules 2026 Apr;358:151727
ANGPT2/Tie2 Enhances H3K18la-Mediated Macrophage M2 Polarization to Promote Endothelial Cell Proliferation in the Chronically Ischaemic Brain.
Tai C, Ling C, Yang Y, Mo N, Yao C, Lv S, Zhang B, Wang H, Chen C
CNS neuroscience & therapeutics 2026 Apr;32(4):e70879
CNS neuroscience & therapeutics 2026 Apr;32(4):e70879
The Dual Role of Gastrodin in Spinal Cord Injury: Microglial Phenotype Switching and Neuronal Survival via PI3K/AKT Activation.
Feng J, Gao S, Hu Y, Sheng W
CNS neuroscience & therapeutics 2026 Apr;32(4):e70811
CNS neuroscience & therapeutics 2026 Apr;32(4):e70811
Wine-Processed Cornus officinalis Ameliorates Osteoarthritis via Modulating M1/M2 Macrophage Polarization.
Fu Y, Zhao M, Huang X, Ren Y, Wang W
Journal of cellular and molecular medicine 2026 Apr;30(7):e71113
Journal of cellular and molecular medicine 2026 Apr;30(7):e71113
Thermosensitive hydrogel delivers nanoparticles for the modulation of immune homeostasis for salpingitis therapy.
Zhang X, Wang S, Chen X, Luo H, Wang J, Wang S, Long Z, He B, Xu X, Yu X, Zheng Y
Acta biomaterialia 2026 Apr;214:210-225
Acta biomaterialia 2026 Apr;214:210-225
Lycium Barbarum Polysaccharide Attenuates Staphylococcus aureus-Induced Mastitis via the Gut Microbiota-Derived Indole-3-Propionic Acid/AhR-IL-22-STAT3 Axis.
Li K, Ran X, Ding H, Han J, Zhang L, Wang X, Guo W, Li Y, Fu S, Bi J
Journal of agricultural and food chemistry 2026 Apr 22;74(15):12038-12053
Journal of agricultural and food chemistry 2026 Apr 22;74(15):12038-12053
Platelet factors 4 produces an antidepressant effect in mice via inhibition of neuroinflammation.
Li YH, Zhan JQ, Zhao Y, Ouyang ZY, Luo LQ, Wei B, Yang YJ
Journal of advanced research 2026 Apr 15;
Journal of advanced research 2026 Apr 15;
Targeting Reactive Oxygen Species and Inflammation in Sepsis-Induced Liver Injury with Naturally Derived Superoxide Dismutase-Mimicking Carbon Dots.
Zhong C, Song N, Huang P, Han L, Zhang J, Lu Z, Wang L
Biomaterials research 2025;29:0249
Biomaterials research 2025;29:0249
A Biodegradable Zinc Alloy Membrane with Regulation of Macrophage Polarization for Early Vascularized Bone Regeneration.
Yi L, Tang R, Shao C, Chen C, Tang J, Liao L, Chen L
Biomaterials research 2025;29:0223
Biomaterials research 2025;29:0223
Ginsenoside Rh2-Pretreated Mesenchymal Stem Cell Exosomes Ameliorate Collagen-Induced Arthritis via N6-Methyladenosine Methylation.
Zhou Z, Wu S, Li Y, Shao P, Jiang J
Biomaterials research 2025;29:0220
Biomaterials research 2025;29:0220
Tumor-associated macrophages drive heterogenetic CD10(High) cancer stem cells to implement tumor-associated neutrophils reprogramming in oral squamous cell carcinoma.
You Y, Du Z, Tian Z, Li S, Yu F, Xiao M, He Y, Wang Y
International journal of biological sciences 2025;21(3):1110-1126
International journal of biological sciences 2025;21(3):1110-1126
Protective effect of Pinacidil on hypoxic-reoxygenated cardiomyocytes in vitro and in vivo via HIF-1α/HRE pathway.
Wang Y, Wang J, Chen L, Zhou W, He H, Chen X, Wang H
PloS one 2025;20(2):e0318859
PloS one 2025;20(2):e0318859
Berberine-taxifolin co-administration attenuates inflammatory response and intestinal barrier injury via nf-κB/NLRP3 suppression in colitis.
Miao G, Zhang D, Sui Z, Leng J, Deng Y, Gu X, Cao H
Frontiers in immunology 2025;16:1725084
Frontiers in immunology 2025;16:1725084
IL-19 suppresses Hippo signaling via modulating YAP1 phosphorylation in osteoarthritis.
Deng J, Gu J, Gong X, Tang H, Cai Y, Yang Y, Dong S, Zhao C
Frontiers in immunology 2025;16:1630253
Frontiers in immunology 2025;16:1630253
Integrative analysis of single-cell and microarray data reveals SPI1-centered macrophage regulatory signatures in ulcerative colitis.
Yu Y, Yu C, Dai S, Liu Y, Hu L, Lu W
Frontiers in genetics 2025;16:1617834
Frontiers in genetics 2025;16:1617834
Acetylcholine from tuft cells promotes M2 macrophages polarization in Hirschsprung-associated enterocolitis.
Zheng Z, Lin L, Lin H, Zhou J, Wang Z, Wang Y, Chen J, Lai C, Li R, Shen Z, Zhong M, Xie C, Chen Y, Zhang X, Guo Z, Dong R, He S, Chen F
Frontiers in immunology 2025;16:1559966
Frontiers in immunology 2025;16:1559966
Curdione combined with borneol treats bacterial mixed HPV infection by regulating the crosstalk among immune cells.
Liu J, Shu T, Mu Y, Zheng W, Lu X, Tao H
Frontiers in immunology 2025;16:1503355
Frontiers in immunology 2025;16:1503355
Bioinspired exosome-SiO(2) nanohybrid therapeutic for rheumatoid arthritis treatment.
Zhu Q, Chen R, Wu X, Zhou Y, Wang Z, Zhang H, Zhu H, Sun L, Shuai Z
Theranostics 2025;15(13):6553-6571
Theranostics 2025;15(13):6553-6571
Polyphenol and metal ion-reinforced supermolecular hydrogels incorporating nanofiber drug and peptide for annulus fibrosus regeneration.
Xin L, Li X, Yang Y, Chen P, Li Y, Liu J, Chen K, Su P, Feng S, He S, Xu X, Wang W, Xu W
Theranostics 2025;15(12):5756-5771
Theranostics 2025;15(12):5756-5771
Normal butanol fraction of Polygonum hydropiper L. flavonoids reduces inflammation caused by PCV2 infections in cell and mouse models.
Wei YH, Zhou SM, Zhao W, Chen Q, Wang QH, Yu ML, Wei YY, Hu TJ
Frontiers in veterinary science 2025;12:1539448
Frontiers in veterinary science 2025;12:1539448
Ascorbic acid deficiency promotes metabolic remodeling and pulmonary fibrosis that leads to respiratory failure in Sod1 and Akr1a double-knockout mice.
Osaki T, Homma T, Soma Y, Miyata S, Matsuda Y, Fujii J
Redox biology 2025 Sep;85:103749
Redox biology 2025 Sep;85:103749
Peptide-Enhanced Bioactive Hydrogel Combined with Photodynamic-Phage Synergistic Antibacterial Therapy System Accelerates Infected Wound Healing.
Quan L, Xin Y, Zhang Z, Zhou C, Ao Q
Advanced healthcare materials 2025 Sep;14(24):e2500875
Advanced healthcare materials 2025 Sep;14(24):e2500875
Novel oncolytic adenovirus-based PEPvIII vaccine displays a super antitumor effect in glioma models.
Chen Y, Ren L, Li X, Wu Y, Zhao H, Feng R, Zhang W, Zhao J, Yang P, Mao Q, Xia H
Journal for immunotherapy of cancer 2025 Sep 25;13(9)
Journal for immunotherapy of cancer 2025 Sep 25;13(9)
Dual stimulus-responsive dECM cryogel sequentially regulate bone microenvironment for one-step surgical therapy of chronic osteomyelitis.
Liu H, Liu S, Liao L, Liao H, Pan W, Hu J
Materials today. Bio 2025 Oct;34:102243
Materials today. Bio 2025 Oct;34:102243
Construction and characteristics of an adjustable biomechanical in vitro corneal stromal model simulating keratoconus pathological features.
Li X, Li K, Gu J, Sun X, Liang Y, Ding C, Chen Y, Chen H, Chen J, Cui Z
Materials today. Bio 2025 Oct;34:102130
Materials today. Bio 2025 Oct;34:102130
Magnoflorine ameliorates cartilage degradation in osteoarthritis through inhibition of mitochondrial reactive oxygen species-mediated activation of the NLRP3 inflammasome.
Peng Y, Huang YH, Luo X, Li MC, Xiao QQ, Qiu L, Fu Q
Journal of Asian natural products research 2025 Oct;27(10):1528-1549
Journal of Asian natural products research 2025 Oct;27(10):1528-1549
Chronic intermittent hypoxia exacerbates the progression of NAFLD via SPP1-mediated inflammatory polarization in macrophages.
Lu FY, Chen XX, Li MY, Yan YR, Wang Y, Li SQ, Zhang L, Lin YN, Zhou JP, Zhou LN, Li QY
Free radical biology & medicine 2025 Oct;238:261-274
Free radical biology & medicine 2025 Oct;238:261-274
Translating m6A-Glycolysis Discovery into Therapy: GOQD-Based Multifunctional Bioactive Scaffolds Rejuvenates Bone Repair in Senescence.
Wang Z, Deng T, Chang H, Li Y, Zhang Y, Jiao X, Gan Y
Small (Weinheim an der Bergstrasse, Germany) 2025 Oct;21(43):e07315
Small (Weinheim an der Bergstrasse, Germany) 2025 Oct;21(43):e07315
Targeting inducible nitric oxide synthase with 1400W mitigates septic acute lung injury through inhibiting SLC7A11/GPX4 mediated ferroptosis.
Wang ZY, Zeng T, Wang X, Zhuo X, Zheng JW, Zhu L, Cheng ST, Wan LH
Nitric oxide : biology and chemistry 2025 Oct;158:4-10
Nitric oxide : biology and chemistry 2025 Oct;158:4-10
Alamandine inhibits pathological retinal neovascularization by targeting the MrgD-mediated HIF-1α/VEGF pathway.
Zhao K, Jiang Y, Huang W, Mao Y, Chen Y, Li P, Yang C
Journal of Zhejiang University. Science. B 2025 Oct 7;26(10):1015-1036
Journal of Zhejiang University. Science. B 2025 Oct 7;26(10):1015-1036
Synergistic potential of Berberine and Wogonin improved adipose inflammation and insulin resistance associated with obesity through HIF-α axis.
Zhou Z, Wang M, Zhang X, Xu Y, Li P, Zheng Z, Yang H
Chinese medicine 2025 Oct 3;20(1):155
Chinese medicine 2025 Oct 3;20(1):155
Poliumoside Alleviates Neuroinflammation and Oxidative Stress After Spinal Cord Injury by Activating the PI3K/AKT/mTOR Signaling Pathway.
Li Q, Hong H, Xu G, Xia M, Wang T, Zhou Z, Huang J, Fu Q, Cui Z
Journal of integrative neuroscience 2025 Oct 29;24(10):43900
Journal of integrative neuroscience 2025 Oct 29;24(10):43900
Design of spiro-heterocyclic substituted diaminonaphthalene Keap1-Nrf2 protein-protein interaction inhibitors as novel anti-depressant agents.
Chen Y, Qin Q, Ding W, Yu R, Wang R, Ji H, Yan J, Ma H, Jiang CS, Sun Y, Zhuang C
European journal of medicinal chemistry 2025 Oct 15;296:117848
European journal of medicinal chemistry 2025 Oct 15;296:117848
M2-exo promote orthodontic bone remodeling via the MeCP2-TCF20-HDAC1 axis.
Chen M, Li Y, Yang Z, Chen M, Li J, Bao G, Ma L, Hu J
Stem cell research & therapy 2025 Oct 15;16(1):569
Stem cell research & therapy 2025 Oct 15;16(1):569
Inhibition of inducible nitric oxide synthase (iNOS) alleviates thoracic aortic aneurysm by regulating mitochondrial dynamics.
Zheng ZF, Zhang JJ, Wu LF, Wang XN, Zhang X, Zou BB, Zhao XY, Zheng JY, Wang KF, Guo J, Du WJ, Cao JM
European journal of pharmacology 2025 Oct 15;1005:178071
European journal of pharmacology 2025 Oct 15;1005:178071
Microglia-Derived Exosomal miR-223-3p Targets the RhoB-NF-κB-CCL11 Axis in Astrocytes and Relieves Neuronal Damage in Subarachnoid Hemorrhage.
Zeng F, Liao Z, Li L, Yang B, Lin J
Neurochemical research 2025 Oct 14;50(5):326
Neurochemical research 2025 Oct 14;50(5):326
Tangeretin protects the kidney from ischemia-reperfusion injury by inhibiting inflammatory response through downregulation of MAOA.
Gao J, Liu X, Huang J, Bi X, Hu Y, Chen T, Sun Q, Fang W, Xiao Y
International immunopharmacology 2025 Oct 10;163:115242
International immunopharmacology 2025 Oct 10;163:115242
BFGF alleviates diabetic endothelial dysfunction by downregulating Endoplasmic reticulum stress.
Hu F, Li J, Zhang X, Fu Y, Mao Y, Tong S, Xu H
Acta diabetologica 2025 Nov;62(11):1859-1871
Acta diabetologica 2025 Nov;62(11):1859-1871
Galectin-9 promotes colon cancer development by polarizing macrophages toward the M2 phenotype.
Zhang J, Xu Y, Han X, Gao Y, Wei Z, Sun X
Cancer genetics 2025 Nov;298-299:141-150
Cancer genetics 2025 Nov;298-299:141-150
Protocatechuic aldehyde promotes diabetic wound healing by enhancing angiogenesis via H3K18 lactylation-mediated Acvr1c expression.
Fan W, You Y, Qu Y, Liu G
Molecular immunology 2025 Nov;187:152-165
Molecular immunology 2025 Nov;187:152-165
LXR-β regulates microglial efferocytosis and neuroinflammation in CPSP via STAT6 activation.
Zang H, Hu Y, Ji X, Chen Y, He X, Wan L, Yao W, Zhang C, Zhu C, Liu T
Brain, behavior, and immunity 2025 Nov;130:106089
Brain, behavior, and immunity 2025 Nov;130:106089
SGMS2+ macrophages enhance NR4A3hi NK cell infiltration to improve prognosis and PD-1 treatment efficacy in hepatocellular carcinoma.
Meng F, Nian F, Feng H, Chen Z, Jiang Q, Zhang F, Xu L, Chen Y, Zhang H, Ye T, Yang B
Journal of translational medicine 2025 Nov 28;24(1):13
Journal of translational medicine 2025 Nov 28;24(1):13
Rg1-preconditioned adipose-derived mesenchymal stromal cells alleviate colitis via exosome-mediated Inhibition of macrophage glycolysis through RAS signaling.
Fang Y, Chen Y, Yu X, Zhang J, Zhu W, Mou C, Wang D, Chen A, Zhang R, Liu Q, Li T, Jiang B
Stem cell research & therapy 2025 Nov 28;17(1):68
Stem cell research & therapy 2025 Nov 28;17(1):68
Targeted suppression of CCR7/NF-κB signaling by apoptotic body-inspired colchicine nanovesicles halts atherosclerotic progression.
Chen Q, Peng YS, Zhong Q, Zhang YB, Hu LB, Zhang GY, Xu YX, Dong PN, Shen S, Wang JH, Wang ZG, Zhang HT, Zeng R, Wang H
Journal of nanobiotechnology 2025 Nov 25;23(1):798
Journal of nanobiotechnology 2025 Nov 25;23(1):798
Yiqi Huayu Jiedu decoction enhances pathological response in neoadjuvant chemotherapy-treated gastric cancer patients: A prospective, randomized controlled trial.
Xu S, Wang R, Liu X, Zhang P, Luo C, Zou K, Xiang C, Huan X, Yao W, Li X, Zhang J, Wu Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157410
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157410
M2 macrophages and tumor cells engage in a metabolic feedback loop to drive HCC progression.
Nong Y, Chen X, Zhang B, Lin Z, Wuriniletu, Du C, Liu Q
Scientific reports 2025 Nov 24;15(1):41701
Scientific reports 2025 Nov 24;15(1):41701
Chitosan-based adhesive patch with anti-inflammatory, pro-healing, and immunomodulatory properties for dural defect repair.
Chen F, Peng X, Chen K, Song J, Fan Y, Wang P, Shi X, Cai Z
Carbohydrate polymers 2025 Nov 15;368(Pt 2):124189
Carbohydrate polymers 2025 Nov 15;368(Pt 2):124189
Topical cyclodextrin minocycline inclusion complex inhibited the inflammation in blepharitis-related dry eye disease.
Li J, Cui H, Sun X, Zhu L, Li J, Liu R, Li Z
International immunopharmacology 2025 Nov 14;165:115509
International immunopharmacology 2025 Nov 14;165:115509
CDK5 regulates PPARγ/NF-κB signaling to exacerbate obesity-related osteoarthritis via modulating macrophage polarization and chondrocyte apoptosis.
Li Y, Li H, Chen X, Li X, Su J, Yang S, Xiao W, Deng Z
Cellular & molecular biology letters 2025 Nov 13;30(1):135
Cellular & molecular biology letters 2025 Nov 13;30(1):135
Asymmetric Janus Electrospun Nanofiber Wound Dressing Infused with Antibacterial and Anti-inflammatory Properties.
Zhao J, Liu N, Zeng Y, Zhang Y, Chen L, Zhou J, Liu B, Zhang W, Tang S
Biomacromolecules 2025 Nov 10;26(11):7670-7680
Biomacromolecules 2025 Nov 10;26(11):7670-7680
The compound (E)-2-(3,4-dihydroxystyryl)-3-hydroxy-4H-pyran-4-one alleviates neuroinflammation and cognitive impairment in a mouse model of Alzheimer's disease.
Liu X, Wu W, Li X, Wang C, Chai K, Yuan F, Zheng H, Yao Y, Li C, Ye ZC, Zha D
Neural regeneration research 2025 Nov 1;20(11):3330-3344
Neural regeneration research 2025 Nov 1;20(11):3330-3344
LA-peptide Hydrogel-Regulation of macrophage and fibroblast fates and their crosstalk via attenuating TGF-β to promote scarless wound healing.
Li Z, Zhang L, Wang Y, Zhu Y, Shen H, Yuan J, Li X, Yu Z, Song B
Bioactive materials 2025 May;47:417-431
Bioactive materials 2025 May;47:417-431
PARP14 inhibits microglial activation via NNT to alleviate depressive-like behaviors in mice.
Yu X, Yang T, Wu D, Xu C, Li Z, Sun A, Gao S, Li H, Fan Z, Huang R
Brain, behavior, and immunity 2025 May;126:235-246
Brain, behavior, and immunity 2025 May;126:235-246
GTS-21 alleviates sepsis-induced atrial fibrillation susceptibility by modulating macrophage polarization and Neuregulin-1 secretion.
Zhou J, Wu K, Ma Y, Zhu J, Zhou Y, Zhang Z, Li F, Zeng G, Li S, Tan S, Zhang Y, Wan C, Tu T, Lin Q, Liu Q
International immunopharmacology 2025 May 8;154:114561
International immunopharmacology 2025 May 8;154:114561
Inhibition of CDK5 signaling mediated inflammation in macrophages promotes cutaneous wound healing.
Wang J, Ji L, Gao Y, Sun J, Zhou X, Ding Y, Zhou Z, Guo X, Liu C, Wang Y, Zhang Q, Lv Z, Ma D
Scientific reports 2025 May 27;15(1):18509
Scientific reports 2025 May 27;15(1):18509
METTL3-Driven m6A Modification of Cpt1a Gene in High Fat Diet Related Liver Cancer Tumor Macrophages Facilitates Type II Macrophage Differentiation.
Zhu L, Li X, Wang W
Frontiers in bioscience (Landmark edition) 2025 May 26;30(5):36971
Frontiers in bioscience (Landmark edition) 2025 May 26;30(5):36971
Toxoplasma calcium-dependent protein kinases 3 mediates M1 macrophage polarization by targeting host Arginase-1.
An R, Liu F, Dai N, Li F, Liu X, Cai H, Chen L, Du J
Parasites & vectors 2025 May 20;18(1):181
Parasites & vectors 2025 May 20;18(1):181
M2-ApoBDs as a therapeutic strategy for systemic lupus erythematosus: targeted macrophage reprogramming and treg differentiation.
Ji J, Yang S, Xu Y, He Q, Liang Q, Feng G, Xia Y, Yang M, Huang Y, Yang J, Dong C, Zhao R, Wang Y, Guo G, Sha X, Li J, Guo Y, Gu Z
Journal of nanobiotechnology 2025 May 16;23(1):354
Journal of nanobiotechnology 2025 May 16;23(1):354
Herkinorin ameliorates neuronal damage in a pentylenetetrazol-induced epilepsy rat model through altering microglial and astrocytic activation by inhibiting PARP1 and NF-κB.
Liu Y, Zhao W, Lv X, Wu G, Zhou X, Tian H, Qv X, Sun H, He Y, Zhang Y, Wang C, Tian J
International immunopharmacology 2025 May 16;155:114588
International immunopharmacology 2025 May 16;155:114588
IL-27 accelerates diabetic wound healing by modulating macrophage polarization.
Tao L, Wu S, Wang Q, Xi Z, Zou Y, Cao M, Liang K, Xu W, Hu Q, Ge Y, Yin Z, Ju Z, Liu Z
International immunopharmacology 2025 May 16;155:114575
International immunopharmacology 2025 May 16;155:114575
Baicalin mitigates alcoholic-associated liver disease via SOCS1-driven reprogramming of macrophages.
Huang S, Wang Y, Wen J, Ji W, Zeng Q, Deng K, Li M, Kuang S, Zhang W, Chan M, Zhou C, Lv Z, Huang S
Chinese medicine 2025 May 13;20(1):63
Chinese medicine 2025 May 13;20(1):63
Nicotinamide Adenine Dinucleotide-Loaded Lubricated Hydrogel Microspheres with a Three-Pronged Approach Alleviate Age-Related Osteoarthritis.
Lin Y, Wu H, Wang J, He W, Hou J, Martin VT, Zhu C, Chen Y, Zhong J, Yu B, Lu A, Guan D, Qin G, Chen W
ACS nano 2025 May 13;19(18):17606-17626
ACS nano 2025 May 13;19(18):17606-17626
Paeoniflorin Alleviates Lipopolysaccharide-Induced Neuroinflammation and Depression Through the Keap1/Nrf2/HO-1 Signaling Pathway.
Hu Z, Wang X, Shi T, Yang L, Zhang B, Shang B, He R, Yi S, He J, Hu J, Cao Y
Antioxidants (Basel, Switzerland) 2025 May 13;14(5)
Antioxidants (Basel, Switzerland) 2025 May 13;14(5)
Phytochemical characterization and pharmacological mechanisms of Huazhuo Sanjie Chubi Decoction in treating gouty arthritis: A multivariant approach.
Chen X, Zhong X, Guo J, Jin T, Guan H, Lin J, Zeng M, Zhang Y, Lin Y, Chang D, Zheng Y, Zhou X, Huang M, Su Y
Journal of ethnopharmacology 2025 May 12;347:119731
Journal of ethnopharmacology 2025 May 12;347:119731
Baicalin prevents experimental autoimmune uveitis by promoting macrophage polarization balance through inhibiting the HIF-1α signaling pathway.
Liu B, Peng Y, Wang C, Wei H, Xu S, Liu Y, Yin X, Bi H, Guo D
Scientific reports 2025 May 12;15(1):16424
Scientific reports 2025 May 12;15(1):16424
ISRIB facilitates post-spinal cord injury recovery through attenuation of neuronal apoptosis and modulation of neuroinflammation.
Li Q, Zhang C, Qi E, Wu M, Sun H, Zhang T, Jiang Y, Li H, Jiang R, Li C, Zhao H, Zhou H, Feng S
Journal of orthopaedic translation 2025 Mar;51:119-131
Journal of orthopaedic translation 2025 Mar;51:119-131
Conductive hyaluronic acid/phytanic acid hydrogel to deliver recombinant human amelogenin for diabetic wound repair.
Cui X, Yue Y, Li Z, Shi X, Qian C, Liu Z, Lin J
International journal of biological macromolecules 2025 Mar;297:139864
International journal of biological macromolecules 2025 Mar;297:139864
Acid-Triggered Cascaded Responsive Supramolecular Peptide Alleviates Myocardial Ischemia‒Reperfusion Injury by Restoring Redox Homeostasis and Protecting Mitochondrial Function.
Liao X, Tang M, Li J, Guo R, Zhong C, Chen X, Zhang X, Mo H, Que D, Yu W, Song X, Li H, Cai Y, Yang P
Advanced healthcare materials 2025 Mar;14(7):e2404319
Advanced healthcare materials 2025 Mar;14(7):e2404319
Exploring the active components and potential mechanisms of Zhimu-Huangbai herb-pair in the treatment of depression.
Lei X, Zhao D, Chen T, Li Q, Xue A, Hu Z, Jia F, Li X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Mar;138:156365
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Mar;138:156365
Indole-3-Propionic Acid Attenuates Neuroinflammation and Cognitive Deficits by Inhibiting the RAGE-JAK2-STAT3 Signaling Pathway.
Hao Z, Ji R, Su Y, Wang H, Yang W, Zhang S, Liu Y, Ma S, Guan F, Cui Y
Journal of agricultural and food chemistry 2025 Mar 5;73(9):5208-5222
Journal of agricultural and food chemistry 2025 Mar 5;73(9):5208-5222
Luteolin modulates liver macrophage subtype polarization and play protective role in sepsis induced acute hepatic injury.
Deng L, Yu Q, Kuang G, Wang L, Fan J, Ye L
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2025 Mar 28;74(1):59
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2025 Mar 28;74(1):59
Intranasal Delivery of Hydrophobic AC5216 Loaded Nanoemulsion into Brain To Alleviate Chronic Unpredictable Stress-Induced Depressive-like Behaviors.
Zhang Y, Wang Y, Wang H, Bian L, Gao F, Yao H, Xie J
ACS applied materials & interfaces 2025 Mar 19;17(11):16533-16547
ACS applied materials & interfaces 2025 Mar 19;17(11):16533-16547
Gastrodin Alleviates Lumbar Intervertebral Disc Degeneration by Suppressing the NF-κB and MAPK Pathways.
Hu H, Xie T
Cell biochemistry and biophysics 2025 Jun;83(2):2009-2021
Cell biochemistry and biophysics 2025 Jun;83(2):2009-2021
Activation of GPER1 alleviates white matter injury by promoting microglia M2 polarization through EGFR/Stat3 pathway in intracerebral hemorrhage mice.
Zhang X, Mao J, Li H, Zhang C, Ge H, Zhong J
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2025 Jun;34(6):108315
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2025 Jun;34(6):108315
Multifunctional injectable hydrogel incorporating EGCG-Cu complexes for synergistic antibacterial, immunomodulatory, and osteogenic therapy in periodontitis.
Hu Y, Xu W, Sun L, Ma X, Zhou P, Zhang C, Cai R, Wang X, Yang H, Tao G, Chen J, He Y
Materials today. Bio 2025 Jun;32:101907
Materials today. Bio 2025 Jun;32:101907
Macrophage membrane functionalized composite microspheres promote bone regeneration in periodontitis via manipulating inflammation reversing-osteogenesis coupling.
Song R, Wan Z, Yuan X, Wang N, Gao Y, Zhang L, Ren H, Jin Y, Liu X, Sang J, Yuan Z, Zhao Y
Materials today. Bio 2025 Jun;32:101789
Materials today. Bio 2025 Jun;32:101789
K(+)-H(+) coupling strategy for immune regulation and bone defect repair.
Hu L, Yang K, Chen Y, Wang H, Fu Z, Jiang L, Xu J, Tian H, Zhu Y, Dai Z, Li Y, Chen X, Lin X, Chen P, Gu C, Fan S
Materials today. Bio 2025 Jun;32:101744
Materials today. Bio 2025 Jun;32:101744
3D bioprinted biomimetic MOF-functionalized hydrogel scaffolds for bone regeneration: Synergistic osteogenesis and osteoimmunomodulation.
Yu SY, Wu T, Xu KH, Liu RY, Yu TH, Wang ZH, Zhang ZT
Materials today. Bio 2025 Jun;32:101740
Materials today. Bio 2025 Jun;32:101740
Novel pH-responsive lipid nanoparticles deliver UA-mediated mitophagy and ferroptosis for osteoarthritis treatment.
Yi G, Li M, Zhou J, Li J, Song X, Li S, Liu J, Zhang H, Chen Z
Materials today. Bio 2025 Jun;32:101697
Materials today. Bio 2025 Jun;32:101697
miR-301a-5p regulated IKKβ/NF-κB axis and macrophage polarization to accelerate skin wound healing.
Li Y, Fu Z, Deng C, Qian J, Wang Z, Lu Y, Zhang S, Liu G, Wen J, Chen Y, Jiang J, Liu X, Zheng X, Shen X, Su W, Yang M, Tang J, Wang Y, Meng B, Yang X
International journal of biological macromolecules 2025 Jun;311(Pt 4):143995
International journal of biological macromolecules 2025 Jun;311(Pt 4):143995
Gallic acid promotes M2 macrophage polarization through mitochondrial oxidative phosphorylation in periodontitis.
Zhang R, Yang W, Li K, Zhang X, Liu J, Ai L
Archives of oral biology 2025 Jun;174:106237
Archives of oral biology 2025 Jun;174:106237
TGF-β1 induces autophagy and mediates the effect on macrophages differentiation in primary liver cancer.
Liu C, Li M, Liu L, Xu Q, Zheng L, Wu C, Ren J, Zhang T, Wang H, Lin Z
International immunopharmacology 2025 Jun 5;157:114799
International immunopharmacology 2025 Jun 5;157:114799
Sleep deficiency exacerbates periodontal inflammation via trigeminal TRPV1 neurons.
Li J, Cui Z, Gong H, Zhang Y, Yuan Z, Zhang Z, Ma Z, Zhou N, Huang C, Zhao Y, Li X, Zhang Z, Sun Y
Proceedings of the National Academy of Sciences of the United States of America 2025 Jun 17;122(24):e2424169122
Proceedings of the National Academy of Sciences of the United States of America 2025 Jun 17;122(24):e2424169122
Tumor-derived exosomal miR-425-5p and miR-135b-3p enhance colorectal cancer progression through immune suppression and vascular permeability promotion.
Feng CZ, Zhong SQ, Ye SW, Zheng Z, Sun H, Zhou SH
World journal of gastrointestinal oncology 2025 Jun 15;17(6):106161
World journal of gastrointestinal oncology 2025 Jun 15;17(6):106161
Direct Peritoneal Resuscitation and Melatonin in the Treatment of Abdominal Sepsis-Induced Lung Injury via Macrophage Metabolic Reprogramming.
Zhao Z, Ji J, Ming L, Luo Z, Li M, Chen Y, Sun R, Lu W, Tian W, Yang F, Huang Q
Journal of pineal research 2025 Jul;77(4):e70066
Journal of pineal research 2025 Jul;77(4):e70066
GDF11 Regulates M1 and M2 Polarization of BV2 Microglial Cells via p38 MAPK Signaling Pathway.
Zhao X, Qin R, Li G, Lv G, Zhao D, Kong L, Qi M, Li P
Molecular neurobiology 2025 Jul;62(7):9290-9305
Molecular neurobiology 2025 Jul;62(7):9290-9305
Human dental follicle cell-derived conditioned media enhance periodontal regeneration by regulating the osteogenic differentiation and inflammation of periodontal ligament stem cells and macrophage polarization.
Gao Y, He X, Deng Y, Wang X, Shen J, Xu W, Cai R, Lan X, Chen J, He Y
Molecular and cellular biochemistry 2025 Jul;480(7):4431-4448
Molecular and cellular biochemistry 2025 Jul;480(7):4431-4448
Unveiling the roles of HIPK2 in atherosclerosis: Insights into the β-catenin/STAT1 signaling cascade and the involvement of SENP1.
Zhen Y, Li D, Meng Y, Xing Z, Zheng J
Biochemical pharmacology 2025 Jul;237:116911
Biochemical pharmacology 2025 Jul;237:116911
Umbilical Cord-Mesenchymal Stromal Cell-Derived Extracellular Vesicles Target the Liver to Improve Neurovascular Health in Type 2 Diabetes With Non-Alcoholic Fatty Liver Disease.
Du M, Yang H, Niu J, Huang J, Wang L, Xi J, Meng P, Liu Z, Ma G, Li J, Liu X, Guo L, Hu M, Tian Z, Liu B, Liu W, Shetty AK, Wu S, Baskys A, Long Q
Journal of extracellular vesicles 2025 Jul;14(7):e70125
Journal of extracellular vesicles 2025 Jul;14(7):e70125
Icariin delivery system based on covalent organic framework materials: dual effects of immune modulation and osteogenesis promotion.
Luo M, Lin X, Wang N, Xie Q, Zeng S, Li S, He Z, Lan X
RSC advances 2025 Jul 4;15(29):23783-23800
RSC advances 2025 Jul 4;15(29):23783-23800
Magnetically Driven Biomimetic Microrobot Loaded with Eleutheroside B for Targeted Delivery and Neural Repair in Spinal Cord Injury.
Niu J, Zhang F, Liu C, Xie K, Zhang Y, Zhang J, Wang X, Song C, Li B, Jiang Y, Li T, Wang Y
ACS applied materials & interfaces 2025 Jul 30;17(30):42688-42705
ACS applied materials & interfaces 2025 Jul 30;17(30):42688-42705
Rhein Inhibits Microglia-Mediated Neuroinflammation and Neuronal Damage of Alzheimer's Disease via Regulating the Glutamine-Aspartate-Arginine-NO Metabolic Pathway.
Chi B, Zhang Z, Zhang Z, Zhang H, Tian M, Wang Y, Gao X
International journal of molecular sciences 2025 Jul 3;26(13)
International journal of molecular sciences 2025 Jul 3;26(13)
Preparation, Characterization, and Functional Evaluation of a Novel Recombinant Hypoglycemic Protein with Multifunctional Effects.
Liu T, Ma X, Duan Z
Journal of agricultural and food chemistry 2025 Jul 23;73(29):18366-18379
Journal of agricultural and food chemistry 2025 Jul 23;73(29):18366-18379
Poldip2 Aggravates inflammation in diabetic retinopathy by impairing mitophagy via the AMPK/ULK1/Pink1 pathway.
Lin S, Ji Z, Gao J, Fan J, Hou J, Liu S, Wang C, Chen K, Tao L, Jiang Z
Life sciences 2025 Jul 15;373:123681
Life sciences 2025 Jul 15;373:123681
Astragalus polysaccharide alleviates mastitis disrupted by Staphylococcus aureus infection by regulating gut microbiota and SCFAs metabolism.
Li K, Ran X, Han J, Ding H, Wang X, Li Y, Guo W, Li X, Guo W, Fu S, Bi J
International journal of biological macromolecules 2025 Jan;286:138422
International journal of biological macromolecules 2025 Jan;286:138422
Isosteviol Sodium Promotes Neurological Function Recovery in a Model of Spinal Cord Injury in Rats.
Zhang T, Zhang T, Yu H, Chi L
Immunity, inflammation and disease 2025 Jan;13(1):e70110
Immunity, inflammation and disease 2025 Jan;13(1):e70110
TNFα-reliant FSP1 up-regulation promotes intervertebral disc degeneration via caspase 3-dependent apoptosis.
Qiu C, Cheng L, Di D, Xiang Z, Wang C, Li J, Xiong Y, Li M, Liu J, Zhou J, Liu T, Wang X, Luo D, Wang X, Li S, Wang H, Wang X, Zhao Y, Liu X, Wang L
Genes & diseases 2025 Jan;12(1):101251
Genes & diseases 2025 Jan;12(1):101251
Zuojin Wan Suppresses the Progression of Colorectal Cancer by Inhibiting M2 Tumor-Associated Macrophages Through JAK2/STAT3 Signaling Pathway and In Vivo and In Vitro.
Nong F, Xing S, Cheng W, Deng S
Integrative cancer therapies 2025 Jan-Dec;24:15347354251375951
Integrative cancer therapies 2025 Jan-Dec;24:15347354251375951
Cimicifuga heracleifolia kom. Attenuates ulcerative colitis through the PI3K/AKT/NF-κB signaling pathway.
Wu XY, Dong QW, Zhang YB, Li JX, Zhang MQ, Zhang DQ, Cui YL
Journal of ethnopharmacology 2025 Jan 30;337(Pt 3):118892
Journal of ethnopharmacology 2025 Jan 30;337(Pt 3):118892
Ginsenoside Rd protects against acute liver injury by regulating the autophagy NLRP3 inflammasome pathway.
Zhong X, Sun Y, Lin Y, Deng S, Wang H, Zhou X, Lu J, Zheng Y, Luo R, Huang M, Song J
Scientific reports 2025 Jan 28;15(1):3569
Scientific reports 2025 Jan 28;15(1):3569
TDP43 augments astrocyte inflammatory activity through mtDNA-cGAS-STING axis in NMOSD.
Liu Z, Bai Y, Xu B, Wen H, Chen K, Lin J, Wang Y, Xu J, Wang H, Shi F, Wang J, Wang H
Journal of neuroinflammation 2025 Jan 22;22(1):14
Journal of neuroinflammation 2025 Jan 22;22(1):14
Extracellular Matrix-Mimicking Hydrogel with Angiogenic and Immunomodulatory Properties Accelerates Healing of Diabetic Wounds by Promoting Autophagy.
Pan Y, Li Y, Zhou X, Luo J, Ding Q, Pan R, Tian X
ACS applied materials & interfaces 2025 Jan 22;17(3):4608-4625
ACS applied materials & interfaces 2025 Jan 22;17(3):4608-4625
Nitric Oxide-Releasing Mesoporous Hollow Cerium Oxide Nanozyme-Based Hydrogel Synergizes with Neural Stem Cell for Spinal Cord Injury Repair.
Liu D, Niu R, Wang S, Shao L, Yang X, Liu X, Ma X, Zhu Z, Zhang J, Shi B, Ni H, Du X
ACS nano 2025 Jan 21;19(2):2591-2614
ACS nano 2025 Jan 21;19(2):2591-2614
The malic acid inhibiting inflammation in ankylosing spondylitis by interfering M1 macrophage polarization.
Ji Z, Feng X, Han C, Li S, Wu B, Zhang X, Zhu S, Tong W, Xu W
International immunopharmacology 2025 Jan 10;144:113653
International immunopharmacology 2025 Jan 10;144:113653
CCAAT/Enhancer-Binding Protein Beta Nitration Participates in Hyperhomocysteinemia-Induced Cardiomyocyte Autophagic Flux Blockage by Inhibiting Transcription Factor EB Transcription.
Chai J, Xu J, Zhang S, Yan W, Chen S, Zhu X, Luo C, Wang W
Antioxidants & redox signaling 2025 Feb;42(4-6):165-183
Antioxidants & redox signaling 2025 Feb;42(4-6):165-183
Enhanced hydrogel loading of quercetin-loaded hollow mesoporous cerium dioxide nanoparticles for skin flap survival.
Liu X, Ju Y, Yang P, Shen N, Shao Y, Yang A, Wu R, Lei L, Fang B
Materials today. Bio 2025 Feb;30:101432
Materials today. Bio 2025 Feb;30:101432
Novel full-thickness biomimetic corneal model for studying pathogenesis and treatment of diabetic keratopathy.
Cui Z, Li X, Ou Y, Sun X, Gu J, Ding C, Yu Z, Guo Y, Liang Y, Mao S, Ma JH, Chan HF, Tang S, Chen J
Materials today. Bio 2025 Feb;30:101409
Materials today. Bio 2025 Feb;30:101409
Biomimetic ECM nerve guidance conduit with dynamic 3D interconnected porous network and sustained IGF-1 delivery for enhanced peripheral nerve regeneration and immune modulation.
Wan T, Li QC, Zhang FS, Zhang XM, Han N, Zhang PX
Materials today. Bio 2025 Feb;30:101403
Materials today. Bio 2025 Feb;30:101403
ZIP8 Regulates Inflammation and Macrophage Polarisation in Intervertebral Disc Degeneration via the Wnt/β-Catenin Pathway.
Xu J, Gu H, Zhou K, Wu L, Zhang Y, Bian C, Huang Z, Chen G, Cheng X, Yin X
Journal of cellular and molecular medicine 2025 Feb;29(4):e70431
Journal of cellular and molecular medicine 2025 Feb;29(4):e70431
KAT3B-mediated succinylation of DERL3 suppresses osteogenic differentiation by promoting M1/M2 macrophage polarization.
Yu B, Qiao Y, Sun X, Yin Y
Biochemical pharmacology 2025 Feb;232:116724
Biochemical pharmacology 2025 Feb;232:116724
Pathophysiology-Directed Engineering of a Combination Nanoanalgesic for Neuropathic Pain.
Wang W, Wang Y, Huang X, Wu P, Li L, Zhang Y, Chen Y, Chen Z, Li C, Zhou Y, Zhang J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(8):e2405483
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(8):e2405483
HSPA1A inhibits pyroptosis and neuroinflammation after spinal cord injury via DUSP1 inhibition of the MAPK signaling pathway.
He X, Deng B, Zhang C, Zhang G, Yang F, Zhu D, Yang Y, Ma B, Hu X, Wang Y, Kang X
Molecular medicine (Cambridge, Mass.) 2025 Feb 9;31(1):53
Molecular medicine (Cambridge, Mass.) 2025 Feb 9;31(1):53
Nasal mucosal mesenchymal stem cells promote repair of sciatic nerve injury in rats by modulating the inflammatory microenvironment.
Tang Y, Li Y, Yang W, Tao Z, Shi W, Yu M, Xu B, Lu X
Neuroscience letters 2025 Feb 6;848:138112
Neuroscience letters 2025 Feb 6;848:138112
Blocking the CCL5/CCL7-CCR1 axis regulates macrophage polarization through NF-κB pathway to alleviate the progression of osteoarthritis.
Xu H, He Y, Chen S, Meng C, Liu Q, Huang XJ, You HB
International immunopharmacology 2025 Feb 6;147:114027
International immunopharmacology 2025 Feb 6;147:114027
Methanol Extract of Pueraria lobata (Willd.) Root and Its Active Ingredient, Puerarin, Induce Apoptosis in HeLa Cells and Attenuates Bacterial Vaginosis in Gardnerella vaginalis-Infected Mice.
Lee JH, Lim JY, Jeon YD, Kim DK, Lee DH
International journal of molecular sciences 2025 Feb 5;26(3)
International journal of molecular sciences 2025 Feb 5;26(3)
Phillyrin ameliorates DSS-induced colitis in mice via modulating the gut microbiota and inhibiting the NF-κB/MLCK pathway.
Li T, Hu G, Fu S, Qin D, Song Z
Microbiology spectrum 2025 Feb 4;13(2):e0200624
Microbiology spectrum 2025 Feb 4;13(2):e0200624
Novel HOCl-Responsive Theranostic Prodrug for the Early Diagnosis and Therapy of Ischemic Stroke.
Wang H, Li K, Zhang L, Han T, Mu S, Song Y, Han Z, Zhao H, Liu X, Zhang H
Journal of medicinal chemistry 2025 Feb 27;68(4):4951-4960
Journal of medicinal chemistry 2025 Feb 27;68(4):4951-4960
IL-27 regulates macrophage ferroptosis by inhibiting the Nrf2/HO1 signaling pathway in sepsis-induced ARDS.
Xiong M, Luo R, Zhang Z, Liu P, Peng Q, Xu F, Guo M
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2025 Feb 13;74(1):39
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2025 Feb 13;74(1):39
Cynarin as a potent anti‑osteolytic agent: Targeting MAPK and Nrf2‑Keap1 pathways for osteoclast inhibition and bone protection.
Chao R, Wang Y, Liu Z, Wan T, Mao Y, Xie X, Sun L, Xu W, Chen X, Zhang S
International journal of molecular medicine 2025 Dec;56(6)
International journal of molecular medicine 2025 Dec;56(6)
KNC nanozyme repairs hypoxia ischemia brain damage through ALOX12 mediated lipid peroxidation inhibition.
Dong X, Jiang D, Chen S, Tan J, Zhao J, Liu X, Lu Z, Yeung KWK, Liao Y, Liu X, Ouyang L
Bioactive materials 2025 Dec;54:531-548
Bioactive materials 2025 Dec;54:531-548
Mesenchymal stem cell-derived small extracellular vesicles-loaded GelMA microspheres enhance diabetic wound healing by promoting M2 macrophage polarization through p38 MAPK inhibition.
Li W, Chen J, Yu L, Ding L, Zhang X, Yan L, Shi M
Materials today. Bio 2025 Dec;35:102423
Materials today. Bio 2025 Dec;35:102423
Deoxycholic Acid and Lipoteichoic Acid cooperatively drive macrophage M2/M1 polarization via TGR5/STAT3 and TLR2/NF-κB to fuel HCC progression in obesity.
Wu J, Zheng W, Ding XZ, Jin QP, Ding MX
Metabolism open 2025 Dec;28:100420
Metabolism open 2025 Dec;28:100420
MicroRNA-3473b regulates corticosterone-induced microglial polarization and inflammation through TREM2.
Shi J, Ma C, Liu Y, Yang C, Wu J, Wang X
Journal of pharmacological sciences 2025 Dec;159(4):209-218
Journal of pharmacological sciences 2025 Dec;159(4):209-218
Synovium-On-A-Chip: Simulating the Microenvironment of the Rheumatoid Arthritis Synovium via Multicell Interactions to Target Fibroblast-Like Synoviocytes.
Diao W, Jiao Y, Deng T, Gu J, Wang B, Zhang Q, Wang P, Xu N, Xiao C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(46):e11945
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(46):e11945
Interfacial Coordination-Engineered Emulgel Modulates the Osteo-Immune Microenvironment in Periodontitis Treatment Via HIF1 Signaling Pathway-Induced Metabolic Reprogramming.
Zhang H, Huang X, Chen R, Lin W, Li L, Peng X, Yang X, Chen X, Guo T, Weng J, Li J, Yuan Q, Tan H, Wang M
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(46):e09998
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(46):e09998
Steroid Receptor Coactivator-1 Drives Tumor-Associated Macrophage Reprogramming by Mediating MMP12 Transcription in Pancreatic Cancer Perineural Invasion.
Cheng K, Liu L, Gong M, Ji Y, Bai C, Guo X, Chen H, Pan J, Zhang Y, Yuan Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(45):e16575
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(45):e16575
Microglia-specific interleukin-4 delivery by engineered extracellular vesicles restores inner blood-retinal barrier in diabetic retinopathy via GAS6-MERTK pathway.
Fan Y, Ge P, Wang X, Xu J, Wang J, Li H, Gu Q, Xie H, Lin Y, Lu Y, Wang C, Xie P, Hu Z
Journal of nanobiotechnology 2025 Dec 29;24(1):101
Journal of nanobiotechnology 2025 Dec 29;24(1):101
Ectomesenchymal Stem Cell Transplantation Induces Microglial Polarization and Anti-inflammatory IL-10 Secretion via NF-κB and MAPK Pathways to Mitigate Brain Injury Post-cerebral Hemorrhage.
Li Y, Yang W, Tang Y, Du S, Ye Y, Xu B, Shi W, Zhao X, Lu X
Neurochemical research 2025 Dec 20;51(1):20
Neurochemical research 2025 Dec 20;51(1):20
Palmatine Attenuates Lipopolysaccharide-Induced Acute Lung Injury Via Suppression of NLRP3 Inflammasome Activation, Pyroptosis, and Metabolic Remodeling.
Ning P, Wu J, Long Q, Zheng Y, Gan J, Hu X, Song S, Li X, Jiang M, Ye H, Yu W, He Y, Zheng Y, Gao Z
Inflammation 2025 Dec 20;49(1):11
Inflammation 2025 Dec 20;49(1):11
Genistein ameliorates non-alcoholic fatty liver disease in mice by modulating gut microbiota and hepatic macrophage polarization.
Fang S, Han H, Wang R, Li S, Yang R, Mehmood S, Jia Q
Scientific reports 2025 Dec 18;15(1):44085
Scientific reports 2025 Dec 18;15(1):44085
Protective Effects of Arecoline on LPS-Induced Neuroinflammation in BV2 Microglial Cells.
Zhang X, Cui J, Sun J, Fan B, Wang F, Lu C
International journal of molecular sciences 2025 Dec 16;26(24)
International journal of molecular sciences 2025 Dec 16;26(24)
Astragaloside IV improves cognitive impairment in diabetes by inhibiting calpain-1/NLRP3 mediated microglial activation.
Wang X, Jiang H, Wang H, Zhao C, Ba X
International immunopharmacology 2025 Dec 10;167:115682
International immunopharmacology 2025 Dec 10;167:115682
tsRNA-10105-enriched migrasomes mediate hepatocellular carcinoma immunosuppressive microenvironment by inducing M2 Macrophage polarization.
Pan L, Zhou R, Wen Z, Lin Y, Cai H, Lin C, Xu X, Ruan L, Zeng Y, Zhang H, Zhou Y, Hu X
Experimental cell research 2025 Dec 1;453(2):114729
Experimental cell research 2025 Dec 1;453(2):114729
Microglial-derived nitric oxide regulates amygdala synaptic plasticity to drive chronic pain and depression induced by lumbar disc herniation.
Huang Z, Sun J, Li H, Hu Z, Tan H, Fu Y, Gao L, Peng X, Lou H
Neuropharmacology 2025 Dec 1;280:110662
Neuropharmacology 2025 Dec 1;280:110662
Irisin Alleviates Autoimmune Uveitis Through Promoting Retinal Microglial M1 to M2 Phenotypic Polarization Mediated by HIF-1α Pathway.
Wang M, Huang X, Shu J, Li H, Yang T, Li N, Yang P
Inflammation 2025 Aug;48(4):1716-1727
Inflammation 2025 Aug;48(4):1716-1727
Hyaluronic acid-anchored nanoparticles co-delivering emodin and siRNA confers protection against rheumatoid arthritis via macrophage polarization.
Qin M, Chen P, Chen H, Liu F, He W, Yao E
Materials today. Bio 2025 Aug;33:102074
Materials today. Bio 2025 Aug;33:102074
Black phosphorus nanosheets promote neuronal differentiation of neural stem cells through adhesion and pinocytosis for spinal cord injury repair.
Chen L, Shi L, Wei T, Liu H, Wang Z, Wang H, Li N, Feng S
Acta biomaterialia 2025 Aug;202:529-544
Acta biomaterialia 2025 Aug;202:529-544
Improved prebiotic-based "shield" equipped probiotics for enhanced colon cancer therapy by polarizing M1 macrophages and regulating intestinal microbiota.
Wang Y, Su X, Liu Y, Hu L, Kang L, Xu C, Sun Z, Sun C, Guo H, Shen S
Acta pharmaceutica Sinica. B 2025 Aug;15(8):4225-4247
Acta pharmaceutica Sinica. B 2025 Aug;15(8):4225-4247
Naringenin Accelerates Diabetic Wound Healing via Regulating Macrophage M2 Polarization and Efferocytosis.
Wang B, Huang Y, Ding Y, Chen J, Chen Y, Zhang H, Tan Q
Food science & nutrition 2025 Aug;13(8):e70688
Food science & nutrition 2025 Aug;13(8):e70688
Pyroptosis-responsive microspheres modulate the inflammatory microenvironment to retard osteoporosis in female mice.
Lu S, Cao J, Song Z, Gong F, Yang P, Ge J, He Y, Han Z, Hou G, Zhang Z, Yang Y, Teng Y, Zhang Z, Zou J, Cheng L, Yang H
Nature communications 2025 Aug 30;16(1):8127
Nature communications 2025 Aug 30;16(1):8127
RBM15 enhances paclitaxel resistance in triple-negative breast cancer by targeting m(6)A methylation of TNFSF9 and inducing polarization of tumor-associated macrophages to M2 phenotype.
Fu J, Wei C, Chen Y, He X, Zhang K
Hereditas 2025 Aug 19;162(1):167
Hereditas 2025 Aug 19;162(1):167
Low-Dose, Post-Storage Dancong Tea Attenuates Hydroalcohol-Induced Gastric Damage via Modulation Antioxidant and Anti-Inflammatory Pathways.
Jian H, Chen R, Sun L, Li Q, Cao J, Lai X, Zhang Z, Zhang S, Hao M, Sun S, Chen Z
Foods (Basel, Switzerland) 2025 Aug 12;14(16)
Foods (Basel, Switzerland) 2025 Aug 12;14(16)
Differential expression of lysine-acetylated proteins in the anti-inflammatory effects of luteolin-gadolinium on macrophages.
Zhang H, Tian H, Yu Y, Hao J, Wang L, Qiu R, Wang X, Wang X, Cao H, Shi J
Biochemical and biophysical research communications 2025 Aug 1;773:152072
Biochemical and biophysical research communications 2025 Aug 1;773:152072
Vanillic acid ameliorates collagen-induced arthritis by suppressing the inflammation response via inhibition of the MAPK and NF-κB signaling pathways.
Zhou Y, Li P, Zhi Z, Chen R, Li C, Zhang C
Inflammopharmacology 2025 Apr;33(4):1949-1963
Inflammopharmacology 2025 Apr;33(4):1949-1963
CIP2A promotes bronchiolitis obliterans by activating the NF‑κB pathway.
Zhou X, Zhao X, Li Y, Zhang B
Molecular medicine reports 2025 Apr;31(4)
Molecular medicine reports 2025 Apr;31(4)
sLithospermic acid etched ZIF-8 nanoparticles delays osteoarthritis progression by inhibiting inflammatory signaling pathways and rescuing mitochondrial damage.
Zhang Y, Lou Q, Lian H, Yang R, Cui R, Wang L, Ma B, Hou L, Jin L, Teng W
Materials today. Bio 2025 Apr;31:101589
Materials today. Bio 2025 Apr;31:101589
Strontium-based quaternary ammonium salt chitosan particles for ultrafast hemostasis of open fracture.
Ji M, Yuan Z, Zhu Y, Han F, Zhao C, Yu X, Chen Z, Huang Y, Jiang H, Shi L, Ye C, Wan F, Tao R, Zhou Z
International journal of biological macromolecules 2025 Apr;304(Pt 1):140752
International journal of biological macromolecules 2025 Apr;304(Pt 1):140752
Systemic Lupus Erythematosus Exacerbates Hip Arthritis by Promoting Chondrocyte Pyroptosis in the Femoral Head via Activating the NF-κB Pathway.
Fang X, Zhang H, Zhou H, Shen S, Lao Z, Zhang Z, Bian Y, Zhou C, Jin H, Tong P, Huang Y, Zhou H, Zeng H, Fu F, Wu C, Zheng W, Ruan H
Journal of cellular and molecular medicine 2025 Apr;29(7):e70531
Journal of cellular and molecular medicine 2025 Apr;29(7):e70531
Neutralization of IL-17 and CXCR1 Protects Septic Arthritis by Regulating CXCL8-CXCR1 Pathway Along With Functional Activities in Neutrophils.
Ghosh S, Bishayi B
International journal of rheumatic diseases 2025 Apr;28(4):e70144
International journal of rheumatic diseases 2025 Apr;28(4):e70144
ErTao decoction alleviates liver fibrosis by suppressing STING-mediated macrophages and NLRP3 inflammasome activation.
Jia H, Li J, Chen X, Liu Z, Wu C, Liu C, Zhang J, Luo M, Huang M, Huang S, Cai M, Gao L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156489
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156489
Facile Nanocomposite Hydrogel Scaffold with Sustained Drug Release and Osteo-Immunomodulatory Effects to Enhance Bone Regeneration.
Zhao F, Su Y, Liu H, Zhao Y, Zhang L, Zhuge N, Zhao P, Ning Z, Kang Q, Liu D
ACS applied materials & interfaces 2025 Apr 2;17(13):19286-19303
ACS applied materials & interfaces 2025 Apr 2;17(13):19286-19303
Tannic acid‑cerium nanoenzymes serve as broad-spectrum antioxidants to alleviate acute kidney injury by modulating macrophage polarization, mitophagy and endoplasmic reticulum stress.
Fu H, Wang Y, Huang B, Liang Z, Li Y, Cao Z, Wu J, Zhao Y
Journal of controlled release : official journal of the Controlled Release Society 2025 Apr 10;380:892-909
Journal of controlled release : official journal of the Controlled Release Society 2025 Apr 10;380:892-909
Lack of ALCAT1 enhances the protective effects of aerobic exercise on kidney in HFpEF mice.
Zhang L, Feng L, Zhao Y, Geng Y, Liu R, Ma Y, Bo W, Xi Y, Tian Z
Life sciences 2025 Apr 1;366-367:123500
Life sciences 2025 Apr 1;366-367:123500
Echinatin attenuates acute lung injury and inflammatory responses via TAK1-MAPK/NF-κB and Keap1-Nrf2-HO-1 signaling pathways in macrophages.
Luo L, Wang H, Xiong J, Chen X, Shen X, Zhang H
PloS one 2024;19(5):e0303556
PloS one 2024;19(5):e0303556
Rauwolfia polysaccharide can inhibit the progress of ulcerative colitis through NOS2-mediated JAK2/STAT3 pathway.
Wu H, Jiang F, Yuan W, Zhao Y, Liu N, Miao X
PloS one 2024;19(4):e0301660
PloS one 2024;19(4):e0301660
Artesunate-Nanoliposome-TPP, a Novel Drug Delivery System That Targets the Mitochondria, Attenuates Cisplatin-Induced Acute Kidney Injury by Suppressing Oxidative Stress and Inflammatory Effects.
Zhang J, Gu L, Jiang Y, Ma Y, Zhang Z, Shen S, Shen S, Peng Q, Xiao W
International journal of nanomedicine 2024;19:1385-1408
International journal of nanomedicine 2024;19:1385-1408
Myeloid Deletion of Cdc42 Protects Liver From Hepatic Ischemia-Reperfusion Injury via Inhibiting Macrophage-Mediated Inflammation in Mice.
He J, Tang MY, Liu LX, Kong CX, Chen W, Wang L, Zhi SB, Sun HW, Huang YC, Chen GY, Xin HB, Deng KY
Cellular and molecular gastroenterology and hepatology 2024;17(6):965-981
Cellular and molecular gastroenterology and hepatology 2024;17(6):965-981
Astragalus Polysaccharide Mitigates Rhabdomyolysis-Induced Acute Kidney Injury via Inhibition of M1 Macrophage Polarization and the cGAS-STING Pathway.
Sun C, Zhao X, Wang X, Yu Y, Shi H, Tang J, Sun S, Zhu S
Journal of inflammation research 2024;17:11505-11527
Journal of inflammation research 2024;17:11505-11527
Multifunctionally disordered TiO(2) nanoneedles prevent periprosthetic infection and enhance osteointegration by killing bacteria and modulating the osteoimmune microenvironment.
Chen Y, Zhou L, Guan M, Jin S, Tan P, Fu X, Zhou Z
Theranostics 2024;14(15):6016-6035
Theranostics 2024;14(15):6016-6035
A tantalum-containing zirconium-based metallic glass with superior endosseous implant relevant properties.
Wu Y, Wang F, Huang Y, Zheng F, Zeng Y, Lu Z, Wang S, Sun B, Sun Y
Bioactive materials 2024 Sep;39:25-40
Bioactive materials 2024 Sep;39:25-40
TLR4/TNFR1 blockade suppresses STAT1/STAT3 expression and increases SOCS3 expression in modulation of LPS-induced macrophage responses.
Sawoo R, Bishayi B
Immunobiology 2024 Sep;229(5):152840
Immunobiology 2024 Sep;229(5):152840
Targeted delivery of berberine using bionic nanomaterials for Atherosclerosis therapy.
Wu H, Zhang L, Dong X, Yang J, Zheng L, Li L, Liu X, Jin M, Zhang P
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Sep;178:117135
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Sep;178:117135
Oxysophoridine inhibits oxidative stress and inflammation in hepatic fibrosis via regulating Nrf2 and NF-κB pathways.
Chen JY, Yang YJ, Meng XY, Lin RH, Tian XY, Zhang Y, Lai WF, Yang C, Ma XQ, Huang MQ
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155585
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155585
Study on the involvement of microglial S100A8 in neuroinflammation and microglia activation during migraine attacks.
An N, Zhang Y, Xie J, Li J, Lin J, Li Q, Wang Y, Liu Y, Yang Y
Molecular and cellular neurosciences 2024 Sep;130:103957
Molecular and cellular neurosciences 2024 Sep;130:103957
Dihydroartemisinin Modulates Enteric Glial Cell Heterogeneity to Alleviate Colitis.
Qiu P, Chang Y, Chen X, Wang S, Nie H, Hong Y, Zhang M, Wang H, Xiao C, Chen Y, Liu L, Zhao Q
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Sep;11(35):e2403461
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Sep;11(35):e2403461
The expansion of MDSCs induced by exosomal PD-L1 promotes the progression of gastric cancer.
Li H, Chen X, Zheng S, Han B, Zhang X, Zheng X, Lu Y, Sun Q, Hu X, Wu J
Journal of translational medicine 2024 Sep 3;22(1):821
Journal of translational medicine 2024 Sep 3;22(1):821
Macrophage membrane-camouflaged biomimetic nanoparticles for rheumatoid arthritis treatment via modulating macrophage polarization.
Zhou R, Xue S, Cheng Y, Chen Y, Wang Y, Xing J, Liu H, Xu Y, Lin Y, Pei Z, Wei X, Ding J, Li S, Wang K, Yao F, Zhao Y, Ding C, Hu W
Journal of nanobiotechnology 2024 Sep 19;22(1):578
Journal of nanobiotechnology 2024 Sep 19;22(1):578
Ocotillol-Type Pseudoginsenoside-F11 Alleviates Lipopolysaccharide-Induced Acute Kidney Injury through Regulation of Macrophage Function by Suppressing the NF-κB/NLRP3/IL-1β Signaling Pathway.
Wang Y, Zhang J, Yang Z, Li C, Zhang C, Sun S, Jiao Z, Che G, Gao H, Liu J, Li J
Journal of agricultural and food chemistry 2024 Sep 18;72(37):20496-20512
Journal of agricultural and food chemistry 2024 Sep 18;72(37):20496-20512
RNF31-mediated IKKα ubiquitination aggravates inflammation and intestinal injury through regulating NF-κB activation in human and mouse neonates.
Zhang Y, Tian Y, Zhong X, Zhang R, Yang S, Jin J, Lyu C, Fan J, Shi B, Zhu K, Xiao Y, Lin N, Ma D, Tou J, Shu Q, Lai D
Life sciences 2024 Sep 1;352:122893
Life sciences 2024 Sep 1;352:122893
Aerobic Exercise Protects against Cardiotoxin-Induced Skeletal Muscle Injury in a DDAH1-Dependent Manner.
Feng F, Luo K, Yuan X, Lan T, Wang S, Xu X, Lu Z
Antioxidants (Basel, Switzerland) 2024 Sep 1;13(9)
Antioxidants (Basel, Switzerland) 2024 Sep 1;13(9)
Suppressed testicular macrophage M1 polarization by HDAC5 enforces insensitivity to LPS-elicited blood-testis barrier damage.
Li H, Hu YF, Wang XR, Ouyang KW, Wang H, Wang KW, Chang W, Zhang J, Yuan Z, Xiong YW, Zhu HL, Yang L, Wang H
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Oct;192:114940
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Oct;192:114940
A Janus Microsphere Delivery System Orchestrates Immunomodulation and Osteoinduction by Fine-tuning Release Profiles.
Shi Y, Gu J, Zhang C, Mi R, Ke Z, Xie M, Jin W, Shao C, He Y, Shi J, Xie Z
Small (Weinheim an der Bergstrasse, Germany) 2024 Nov;20(46):e2403835
Small (Weinheim an der Bergstrasse, Germany) 2024 Nov;20(46):e2403835
osa-miR168a, a Plant miRNA That Survives the Process of In Vivo Food Digestion, Attenuates Dextran Sulfate Sodium-Induced Colitis in Mice by Oral Administration.
Xu Q, Li Y, Qin X, Xin Y, Wang J, Zhang Y, Xu K, Yang X, Wang X
Journal of agricultural and food chemistry 2024 Nov 13;72(45):25146-25160
Journal of agricultural and food chemistry 2024 Nov 13;72(45):25146-25160
Bakuchiol regulates TLR4/MyD88/NF-κB and Keap1/Nrf2/HO-1 pathways to protect against LPS-induced acute lung injury in vitro and in vivo.
Zhao L, Zhang Z, Li P, Gao Y, Shi Y
Naunyn-Schmiedeberg's archives of pharmacology 2024 May;397(5):3301-3312
Naunyn-Schmiedeberg's archives of pharmacology 2024 May;397(5):3301-3312
Paeonol interferes with lupus nephritis by regulating M1/M2 polarization of macrophages.
Niu Y, Jin Y, Hao Y, Liang W, Tang F, Qin Z, Liang T, Shi L
Molecular immunology 2024 May;169:66-77
Molecular immunology 2024 May;169:66-77
Arylacryl amides: Design, synthesis and the protection against cisplatin-induced acute kidney injury via TLR4/STING/NF-κB pathway.
Wu X, Zhou L, Li Z, Rong K, Gao S, Chen Y, Zuo J, Tang W
Bioorganic chemistry 2024 May;146:107303
Bioorganic chemistry 2024 May;146:107303
N6-Methyladenosine Modification of lncCCKAR-5 Regulates Autophagy in Human Umbilical Cord Mesenchymal Stem Cells by Destabilizing LMNA and Inhibits Diabetic Wound Healing.
Wang J, Wang X, Chen F, Ning Q, Liu Y, Zhu Y, Wei W, Leng M, Wang Z, Jin P, Li Q
The Journal of investigative dermatology 2024 May;144(5):1148-1160.e15
The Journal of investigative dermatology 2024 May;144(5):1148-1160.e15
CD163+ macrophage density in perimysial connective tissue associated with prognosis in IMNM.
Sun H, Wang ZY, Han Y, Wei XJ, Wang YC, Yu XF
Annals of clinical and translational neurology 2024 May;11(5):1267-1279
Annals of clinical and translational neurology 2024 May;11(5):1267-1279
YY1 Lactylation Aggravates Autoimmune Uveitis by Enhancing Microglial Functions via Inflammatory Genes.
Huang J, Wang X, Li N, Fan W, Li X, Zhou Q, Liu J, Li W, Zhang Z, Liu X, Zeng S, Yang H, Tian M, Yang P, Hou S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 May;11(19):e2308031
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 May;11(19):e2308031
Unmasking the dynamics of Mycoplasma gallisepticum: deciphering HD11 macrophage polarization for innovative infection control strategies.
Wang T, Zhao W, Qi Z, Lv S, Xiao Y, Wang Y, Guo Q, Wang L, Peng X
Poultry science 2024 May;103(5):103652
Poultry science 2024 May;103(5):103652
Genkwanin alleviates intervertebral disc degeneration via regulating ITGA2/PI3K/AKT pathway and inhibiting apoptosis and senescence.
Li M, Yu X, Chen X, Jiang Y, Zeng Y, Ren R, Nie M, Zhang Z, Bao Y, Kang H
International immunopharmacology 2024 May 30;133:112101
International immunopharmacology 2024 May 30;133:112101
Hypoxia-induced TREM1 promotes mesenchymal-like states of glioma stem cells via alternatively activating tumor-associated macrophages.
Dong M, Zhang X, Peng P, Chen Z, Zhang Y, Wan L, Xiang W, Liu G, Guo Y, Xiao Q, Wang B, Guo D, Zhu M, Yu X, Wan F
Cancer letters 2024 May 28;590:216801
Cancer letters 2024 May 28;590:216801
The Therapeutic Effects of Baicalein on the Hepatopulmonary Syndrome in the Rat Model of Chronic Common Bile Duct Ligation.
Zeng Z, Lei Y, Yang C, Wu X, Zhang L, Yang Z, Chen L, Wang X, Belguise K, Li Y, Yi B
Journal of clinical and translational hepatology 2024 May 28;12(5):496-504
Journal of clinical and translational hepatology 2024 May 28;12(5):496-504
MicroRNA-142-3p alleviated high salt-induced cardiac fibrosis via downregulating optineurin-mediated mitophagy.
Li Y, Zhao K, Hu Y, Yang F, Li P, Liu Y
iScience 2024 May 17;27(5):109764
iScience 2024 May 17;27(5):109764
Spinster homolog 2 reduces malignancies of glioblastoma via PTEN/PI3K/AKT pathway.
Liang W, Liu M, Su Y, Wen Y, Wang L, Shan J, Zhao J, Xie K, Wang J
IUBMB life 2024 Mar;76(3):140-160
IUBMB life 2024 Mar;76(3):140-160
Htr2b Promotes M1 Microglia Polarization and Neuroinflammation after Spinal Cord Injury via Inhibition of Neuregulin-1/ErbB Signaling.
Chen W, Gao X, Yang W, Xiao X, Pan X, Li H
Molecular neurobiology 2024 Mar;61(3):1643-1654
Molecular neurobiology 2024 Mar;61(3):1643-1654
Photothermal and Photocatalytic Glycol Chitosan and Polydopamine-Grafted Oxygen Vacancy Bismuth Oxyiodide (BiO(1-x) I) Nanoparticles for the Diagnosis and Targeted Therapy of Diabetic Wounds.
Kong J, Ma S, Chu R, Liu J, Yu H, Mao M, Ge X, Sun Y, Wang Y
Advanced materials (Deerfield Beach, Fla.) 2024 Mar;36(11):e2307695
Advanced materials (Deerfield Beach, Fla.) 2024 Mar;36(11):e2307695
Inhibition of SAT1 alleviates chondrocyte inflammation and ferroptosis by repressing ALOX15 expression and activating the Nrf2 pathway.
Xu J, Ruan Z, Guo Z, Hou L, Wang G, Zheng Z, Zhang X, Liu H, Sun K, Guo F
Bone & joint research 2024 Mar 7;13(3):110-123
Bone & joint research 2024 Mar 7;13(3):110-123
Tibial cortex transverse transport promotes ischemic diabetic foot ulcer healing via enhanced angiogenesis and inflammation modulation in a novel rat model.
Qin W, Liu K, Su H, Hou J, Yang S, Pan K, Yang S, Liu J, Zhou P, Lin Z, Zhen P, Mo Y, Fan B, Li Z, Kuang X, Nie X, Hua Q
European journal of medical research 2024 Mar 6;29(1):155
European journal of medical research 2024 Mar 6;29(1):155
Pentraxin 3 exacerbates psoriasiform dermatitis through regulation of macrophage polarization.
Liu J, Qiu C, Zhou Z, Li J, Zhen Y, Wang R, Zhuang Y, Zhang F
International immunopharmacology 2024 Mar 30;130:111805
International immunopharmacology 2024 Mar 30;130:111805
Roseburia intestinalis sensitizes colorectal cancer to radiotherapy through the butyrate/OR51E1/RALB axis.
Dong J, Wang B, Xiao Y, Liu J, Wang Q, Xiao H, Jin Y, Liu Z, Chen Z, Li Y, Fan S, Li Y, Cui M
Cell reports 2024 Mar 26;43(3):113846
Cell reports 2024 Mar 26;43(3):113846
Peroxiredoxin 3 has a crucial role in the macrophage polarization by regulating mitochondrial homeostasis.
Huang W, Wang L, Huang Z, Sun Z, Zheng B
Respiratory research 2024 Mar 2;25(1):110
Respiratory research 2024 Mar 2;25(1):110
Protective effect of Tao Hong Si Wu Decoction against inflammatory injury caused by intestinal flora disorders in an ischemic stroke mouse model.
Zhang L, Xue S, Fei C, Yu C, Li J, Li Y, Wang N, Chu F, Pan L, Duan X, Peng D
BMC complementary medicine and therapies 2024 Mar 18;24(1):124
BMC complementary medicine and therapies 2024 Mar 18;24(1):124
Independent prognostic value of CLDN6 in bladder cancer based on M2 macrophages related signature.
Qi D, Lu Y, Qu H, Dong Y, Jin Q, Sun M, Li Y, Quan C
iScience 2024 Mar 15;27(3):109138
iScience 2024 Mar 15;27(3):109138
Corydalis tomentella Franch. Exerts anti-inflammatory and analgesic effects by regulating the calcium signaling pathway.
Jin S, Li Y, Luo C, Cheng X, Tao W, Li H, Wang W, Qin M, Xie G, Han F
Journal of ethnopharmacology 2024 Mar 1;321:117499
Journal of ethnopharmacology 2024 Mar 1;321:117499
Wogonin alleviates sepsis-induced acute lung injury by modulating macrophage polarization through the SIRT1-FOXO1 pathways.
Ge J, Yang H, Yu N, Lin S, Zeng Y
Tissue & cell 2024 Jun;88:102400
Tissue & cell 2024 Jun;88:102400
Targeted Repair of Spinal Cord Injury Based on miRNA-124-3p-Loaded Mesoporous Silica Camouflaged by Stem Cell Membrane Modified with Rabies Virus Glycoprotein.
Fan X, Shi L, Yang Z, Li Y, Zhang C, Bai B, Chen L, Yilihamu EE, Qi Z, Li W, Xiao P, Liu M, Qiu J, Yang F, Ran N, Shang Y, Liu J, Zhang T, Kong X, Liu H, Zhou H, Feng S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jun;11(21):e2309305
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jun;11(21):e2309305
COL8A1 is a potential prognostic biomarker associated with migration, proliferation, and tumor microenvironment in glioma.
Liu M, Liang W, Su Y, Wen Y, Qi J, Wang L, Su S, Zhao J, Shan J, Wang J
Experimental cell research 2024 Jun 1;439(1):114076
Experimental cell research 2024 Jun 1;439(1):114076
Absence of PD-L1 signaling hinders macrophage defense against Mycobacterium tuberculosis via upregulating STAT3/IL-6 pathway.
Qu P, Li X, Liu W, Zhou F, Xu X, Tang J, Sun M, Li J, Li H, Han Y, Hu C, Lei Y, Pan Q, Zhan L
Microbes and infection 2024 Jul-Aug;26(5-6):105352
Microbes and infection 2024 Jul-Aug;26(5-6):105352
Icariside II modulates pulmonary fibrosis via PI3K/Akt/β-catenin pathway inhibition of M2 macrophage program.
Deng L, Ouyang B, Tang W, Wang N, Yang F, Shi H, Zhang Z, Yu H, Chen M, Wei Y, Dong J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul 25;130:155687
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul 25;130:155687
Comprehensive molecular characterization of long-term glioblastoma survivors.
Xu H, Chen X, Sun Y, Hu X, Zhang X, Wang Y, Tang Q, Zhu Q, Song K, Chen H, Sheng X, Yao Y, Zhuang D, Chen L, Mao Y, Qin Z
Cancer letters 2024 Jul 1;593:216938
Cancer letters 2024 Jul 1;593:216938
Small Extracellular Vesicles Derived from Altered Peptide Ligand-Loaded Dendritic Cell Act as A Therapeutic Vaccine for Spinal Cord Injury Through Eliciting CD4(+) T cell-Mediated Neuroprotective Immunity.
Wang S, Li G, Liang X, Wu Z, Chen C, Zhang F, Niu J, Li X, Yan J, Wang N, Li J, Wang Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jan;11(3):e2304648
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jan;11(3):e2304648
Intermittent mild cold stimulation alleviates cold stress-induced pulmonary fibrosis by inhibiting the TGF-β1/Smad signaling pathway in broilers.
Wei H, Zhang Y, Li T, Zhang S, Yin J, Liu Y, Xing L, Bao J, Li J
Poultry science 2024 Jan;103(1):103246
Poultry science 2024 Jan;103(1):103246
iNOS inhibitor S-methylisothiourea alleviates smoke inhalation-induced acute lung injury by suppressing inflammation and macrophage infiltration.
Shi Y, Cao Y, Han X, Xie L, Xiao K
International immunopharmacology 2024 Jan 5;126:111097
International immunopharmacology 2024 Jan 5;126:111097
COL6A3 enhances the osteogenic differentiation potential of BMSCs by promoting mitophagy in the osteoporotic microenvironment.
Wang K, Peng X, Zhang R, Wu X, Mao L
Molecular biology reports 2024 Jan 25;51(1):206
Molecular biology reports 2024 Jan 25;51(1):206
Epigenetic modification of TWIST1 in macrophages promotes hypertension-induced atherosclerotic plaque instability.
Sun Y, Yao J, Wang C, Jin Y, Wan X, Meng Q, Wu J, Liu Q, Sun H
International immunopharmacology 2024 Jan 25;127:111313
International immunopharmacology 2024 Jan 25;127:111313
Edaravone dexborneol alleviates cerebral ischemia-reperfusion injury through NF-κB/NLRP3 signal pathway.
Shen G, Lou C, Li Q, Zhao B, Luo Y, Wu F, Jiao D, Fang M, Geng Y
Anatomical record (Hoboken, N.J. : 2007) 2024 Feb;307(2):372-384
Anatomical record (Hoboken, N.J. : 2007) 2024 Feb;307(2):372-384
Multi-Omics Profiling Identifies Microglial Annexin A2 as a Key Mediator of NF-κB Pro-inflammatory Signaling in Ischemic Reperfusion Injury.
Tian X, Yang W, Jiang W, Zhang Z, Liu J, Tu H
Molecular & cellular proteomics : MCP 2024 Feb;23(2):100723
Molecular & cellular proteomics : MCP 2024 Feb;23(2):100723
Troxerutin dampened hypothalamic neuroinflammation via microglial IL-22/IL-22R1/IRF3 activation in dihydrotestosterone-induced polycystic ovary syndrome rats.
Gao Z, Tan H, Song X, Zhuang T, Kong R, Wang Y, Yan X, Yao R
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Feb;124:155280
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Feb;124:155280
FAM76B regulates PI3K/Akt/NF-κB-mediated M1 macrophage polarization by influencing the stability of PIK3CD mRNA.
Wang J, Zhao X, Wang Q, Zheng X, Simayi D, Zhao J, Yang P, Mao Q, Xia H
Cellular and molecular life sciences : CMLS 2024 Feb 29;81(1):107
Cellular and molecular life sciences : CMLS 2024 Feb 29;81(1):107
Integrated-omics profiling unveils the disparities of host defense to ECM scaffolds during wound healing in aged individuals.
Chen SD, Chu CY, Wang CB, Yang Y, Xu ZY, Qu YL, Man Y
Biomaterials 2024 Dec;311:122685
Biomaterials 2024 Dec;311:122685
A Novel Compound Ligusticum Cycloprolactam Alleviates Neuroinflammation After Ischemic Stroke via the FPR1/NLRP3 Signaling Axis.
Gao J, Su G, Liu J, Song J, Chen W, Chai M, Xie X, Wang M, Liu J, Zhang Z
CNS neuroscience & therapeutics 2024 Dec;30(12):e70158
CNS neuroscience & therapeutics 2024 Dec;30(12):e70158
Single-cell RNA sequencing reveals the intercellular crosstalk and the regulatory landscape of stromal cells during the whole life of the mouse ovary.
Jiang W, Sun W, Peng Y, Xu H, Fan H, Jin X, Xiao Y, Wang Y, Yang P, Shu W, Li J
Life medicine 2024 Dec;3(6):lnae041
Life medicine 2024 Dec;3(6):lnae041
The plant extract PNS mitigates atherosclerosis via promoting Nrf2-mediated inhibition of ferroptosis through reducing USP2-mediated Keap1 deubiquitination.
Zhao Y, Zheng G, Yang S, Liu S, Wu Y, Miao Y, Liang Z, Hua Y, Zhang J, Shi J, Li D, Cheng Y, Zhang Y, Chen Y, Fan G, Ma C
British journal of pharmacology 2024 Dec;181(23):4822-4844
British journal of pharmacology 2024 Dec;181(23):4822-4844
Inosine Prevents Colorectal Cancer Progression by Inducing M1 Phenotypic Polarization of Macrophages.
Ma Y, Qian X, Yu Q, Dong Y, Wang J, Liu H, Xiao H
Molecules (Basel, Switzerland) 2024 Dec 31;30(1)
Molecules (Basel, Switzerland) 2024 Dec 31;30(1)
The PD-1 /PD-L1 signaling pathway regulates decidual macrophage polarization and may participate in preeclampsia.
Du X, Liu H, Shi J, Yang P, Gu Y, Meng J
Journal of reproductive immunology 2024 Aug;164:104258
Journal of reproductive immunology 2024 Aug;164:104258
Mechanically induced M2 macrophages are involved in bone remodeling of the midpalatal suture during palatal expansion.
Li L, Zhai M, Cheng C, Cui S, Wang J, Zhang Z, Liu J, Wei F
Progress in orthodontics 2024 Aug 5;25(1):30
Progress in orthodontics 2024 Aug 5;25(1):30
Effect of Scaffold Geometrical Structure on Macrophage Polarization during Bone Regeneration Using Honeycomb Tricalcium Phosphate.
Takabatake K, Tsujigiwa H, Nakano K, Chang A, Piao T, Inada Y, Arashima T, Morimatsu A, Tanaka A, Kawai H, Nagatsuka H
Materials (Basel, Switzerland) 2024 Aug 19;17(16)
Materials (Basel, Switzerland) 2024 Aug 19;17(16)
Inhibiting PRMT1 protects against CoNV by regulating macrophages through the FGF2/PI3K/Akt pathway.
Gao Y, Mao J, Zhang R, Deng Q, Wang Y, Pan Y, Liudi S, Wang Y, Fan X, Yang Y, Wan S
European journal of pharmacology 2024 Aug 15;977:176673
European journal of pharmacology 2024 Aug 15;977:176673
S100A9, as a potential predictor of prognosis and immunotherapy response for GBM, promotes the malignant progression of GBM cells and migration of M2 macrophages.
Ji Q, Li Z, Guo Y, Zhang X
Aging 2024 Aug 13;16(15):11513-11534
Aging 2024 Aug 13;16(15):11513-11534
Modulation of secretory factors by lipofundin contributes to its anti‑neuroinflammatory effects.
Chen MS, Hu CL, Jiang SK, Chong ZY, Chen JC
Experimental and therapeutic medicine 2024 Apr;27(4):169
Experimental and therapeutic medicine 2024 Apr;27(4):169
Phenolics and terpenoids with good anti-inflammatory activity from the fruits of Amomum villosum and the anti-inflammatory mechanism of active diterpene.
Xu Y, Sun D, Xiong L, Zhang Z, Li Y, Liu K, Li H, Chen L
Bioorganic chemistry 2024 Apr;145:107190
Bioorganic chemistry 2024 Apr;145:107190
Dehydroandrographolide facilitates M2 macrophage polarization by downregulating DUSP3 to inhibit sepsis-associated acute kidney injury.
Shao Y, Yu W, Cai H
Immunity, inflammation and disease 2024 Apr;12(4):e1249
Immunity, inflammation and disease 2024 Apr;12(4):e1249
Pyxinol Fatty Acid Ester Derivatives J16 against AKI by Selectively Promoting M1 Transition to M2c Macrophages.
Wang Y, Li C, Chen J, Cui X, Wang B, Wang Y, Wang D, Liu J, Li J
Journal of agricultural and food chemistry 2024 Apr 3;72(13):7074-7088
Journal of agricultural and food chemistry 2024 Apr 3;72(13):7074-7088
Multiscale architecture design of 3D printed biodegradable Zn-based porous scaffolds for immunomodulatory osteogenesis.
Li S, Yang H, Qu X, Qin Y, Liu A, Bao G, Huang H, Sun C, Dai J, Tan J, Shi J, Guan Y, Pan W, Gu X, Jia B, Wen P, Wang X, Zheng Y
Nature communications 2024 Apr 11;15(1):3131
Nature communications 2024 Apr 11;15(1):3131
Adhesive hydrogel releases protocatechualdehyde-Fe(3+) complex to promote three healing stages for accelerated therapy of oral ulcers.
Wang Y, Pan Z, Cui J, Zhang X, Li D, Sun H, Yang B, Li Y
Acta biomaterialia 2024 Apr 1;178:68-82
Acta biomaterialia 2024 Apr 1;178:68-82
Strontium Ranelate Ameliorates Intervertebral Disc Degeneration via Regulating TGF-β1/NF-κB Axis.
Sun R, Zhu J, Sun K, Gao L, Zheng B, Shi J
International journal of medical sciences 2023;20(13):1679-1697
International journal of medical sciences 2023;20(13):1679-1697
Shikimic acid (SA) inhibits neuro-inflammation and exerts neuroprotective effects in an LPS-induced in vitro and in vivo model.
Bao X, Zheng Z, Lv J, Bao J, Chang S, Jiang X, Xin Y
Frontiers in pharmacology 2023;14:1265571
Frontiers in pharmacology 2023;14:1265571
The role of the SGK3/TOPK signaling pathway in the transition from acute kidney injury to chronic kidney disease.
Shu H, Wang Y, Zhang H, Dong Q, Sun L, Tu Y, Liao Q, Feng L, Yao L
Frontiers in pharmacology 2023;14:1169054
Frontiers in pharmacology 2023;14:1169054
Jianpi Yangzheng Xiaozheng decoction alleviates gastric cancer progression via suppressing exosomal PD-L1.
Chen Y, Liu J, Chen Y, Zhang R, Tao J, Chen X, Wang H, Sun Q, Wu J, Liu S
Frontiers in pharmacology 2023;14:1159829
Frontiers in pharmacology 2023;14:1159829
Ethyl-acetate fraction from a cinnamon-cortex extract protects pancreatic β-cells from oxidative stress damage.
Li W, Qiao J, Lin K, Sun P, Wang Y, Peng Q, Ye X, Liu W, Sun B
Frontiers in pharmacology 2023;14:1111860
Frontiers in pharmacology 2023;14:1111860
TSAb Modulates Microglia M1 Polarization via Activation of the TSHR-Mediated NF-κB Signaling Pathway.
Liu Y, Yang H, Wu X, Kuang Y, Ban B, Liang Z, Li L, Huang Z, Lu D, Qin Y, Liang X, Luo Z
Neuroendocrinology 2023;113(4):470-478
Neuroendocrinology 2023;113(4):470-478
BMP7 Attenuates Neuroinflammation after Spinal Cord Injury by Suppressing the Microglia Activation and Inducing Microglial Polarization Via the STAT3 Pathway.
Wei X, Huang C, Chen K, Liu S, Wang M, Yang L, Wang Y
Neurochemical research 2023 Sep;48(9):2687-2700
Neurochemical research 2023 Sep;48(9):2687-2700
CD73 inhibits titanium particle-associated aseptic loosening by alternating activation of macrophages.
Sun Z, Kang J, Yang S, Zhang Y, Huang N, Zhang X, Du G, Jiang J, Ning B
International immunopharmacology 2023 Sep;122:110561
International immunopharmacology 2023 Sep;122:110561
DDAH1 Protects against Cardiotoxin-Induced Muscle Injury and Regeneration.
Feng F, Cui B, Fang L, Lan T, Luo K, Xu X, Lu Z
Antioxidants (Basel, Switzerland) 2023 Sep 13;12(9)
Antioxidants (Basel, Switzerland) 2023 Sep 13;12(9)
ASIC1a-CMPK2-mediated M1 macrophage polarization exacerbates chondrocyte senescence in osteoarthritis through IL-18.
Dong L, Zhao Y, Sun C, Ou Yang Z, Chen F, Hu W, Zhang H, Wang Y, Zhu R, Cheng Y, Chen Y, Li S, Wang K, Ding C, Zhou R, Hu W
International immunopharmacology 2023 Nov;124(Pt A):110878
International immunopharmacology 2023 Nov;124(Pt A):110878
Chromofungin, a chromogranin A-derived peptide, protects against sepsis-induced acute lung injury by inhibiting LBP/TLR4-dependent inflammatory signaling.
Zhou W, Kang S, Wang F, Qin Y, Liu J, Xiao X, Chen X, Zhang D
European journal of pharmacology 2023 Nov 5;958:176043
European journal of pharmacology 2023 Nov 5;958:176043
Hesperidin mitigates oxidative stress-induced ferroptosis in nucleus pulposus cells via Nrf2/NF-κB axis to protect intervertebral disc from degeneration.
Zhu J, Sun R, Yan C, Sun K, Gao L, Zheng B, Shi J
Cell cycle (Georgetown, Tex.) 2023 May;22(10):1196-1214
Cell cycle (Georgetown, Tex.) 2023 May;22(10):1196-1214
Epsin1-mediated exosomal sorting of Dll4 modulates the tubular-macrophage crosstalk in diabetic nephropathy.
Liu JL, Zhang L, Huang Y, Li XH, Liu YF, Zhang SM, Zhao YE, Chen XJ, Liu Y, He LY, Dong Z, Liu FY, Sun L, Xiao L
Molecular therapy : the journal of the American Society of Gene Therapy 2023 May 3;31(5):1451-1467
Molecular therapy : the journal of the American Society of Gene Therapy 2023 May 3;31(5):1451-1467
Expression pattern analysis of m6A regulators reveals IGF2BP3 as a key modulator in osteoarthritis synovial macrophages.
Lu Y, Zhang H, Pan H, Zhang Z, Zeng H, Xie H, Yin J, Tang W, Lin R, Zeng C, Cai D
Journal of translational medicine 2023 May 22;21(1):339
Journal of translational medicine 2023 May 22;21(1):339
Ergosterol Isolated from Antrodia camphorata Suppresses LPS-Induced Neuroinflammatory Responses in Microglia Cells and ICR Mice.
Sun P, Li W, Guo J, Peng Q, Ye X, Hu S, Liu Y, Liu W, Chen H, Qiao J, Sun B
Molecules (Basel, Switzerland) 2023 Mar 6;28(5)
Molecules (Basel, Switzerland) 2023 Mar 6;28(5)
Long-Term Immunogenicity and In Vitro Prophylactic Protective Efficacy of M. tuberculosis Fusion Protein DR2 Combined with Liposomal Adjuvant DIMQ as a Boosting Vaccine for BCG.
Mao LR, Du JP, Wang XC, Xu LF, Zhang YP, Sun QS, Shi ZL, Xing YR, Su YX, Wang SJ, Wang J, Ma JL, Zhang JY
ACS infectious diseases 2023 Mar 10;9(3):593-608
ACS infectious diseases 2023 Mar 10;9(3):593-608
Atrazine induces phagocytotic dysfunction of microglia depends on nucleocytoplasmic translocation of acetylated HMGB1.
Shi G, Zhang C, Li G, Wang K, Cai Q, Huang M
Ecotoxicology and environmental safety 2023 Mar 1;252:114583
Ecotoxicology and environmental safety 2023 Mar 1;252:114583
MAGL regulates synovial macrophage polarization vis inhibition of mitophagy in osteoarthritic pain.
Gu C, Chen M, Li X, Geng D, Wang C
Molecular medicine reports 2023 Jun;27(6)
Molecular medicine reports 2023 Jun;27(6)
Ent-kauranes and ent-atisanes from Euphorbia wallichii and their anti-inflammatory activity.
Wang Y, Jiang Q, Sun D, Zhang N, Lin Y, Li H, Chen L
Phytochemistry 2023 Jun;210:113643
Phytochemistry 2023 Jun;210:113643
Disturbance of neuron-microglia crosstalk mediated by GRP78 in Neuropsychiatric systemic lupus erythematosus mice.
Xu J, Yang C, Zeng S, Wang X, Yang P, Qin L
Journal of neuroinflammation 2023 Jun 26;20(1):150
Journal of neuroinflammation 2023 Jun 26;20(1):150
NLRP3 activation in microglia contributes to learning and memory impairment induced by chronic lead exposure in mice.
Zhu J, Zhou F, Zhou Q, Xu Y, Li Y, Huang D, Chen L, Liu A, Zou F, Meng X
Toxicological sciences : an official journal of the Society of Toxicology 2023 Jan 31;191(1):179-191
Toxicological sciences : an official journal of the Society of Toxicology 2023 Jan 31;191(1):179-191
Macrophages contribute to periodontal wound healing mainly in the tissue proliferation stage.
Chen B, Li S, Chang Y, Zhang J, Liu J, Dong Y, Yan F
Journal of periodontal research 2023 Feb;58(1):122-130
Journal of periodontal research 2023 Feb;58(1):122-130
MiR-29c Inhibits TNF-α-Induced ROS Production and Apoptosis in Mouse Hippocampal HT22 Cell Line.
Li B, Lu Y, Wang R, Xu T, Lei X, Jin H, Gao X, Xie Y, Liu X, Zeng J
Neurochemical research 2023 Feb;48(2):519-536
Neurochemical research 2023 Feb;48(2):519-536
Cyasterone inhibits IL-1β-mediated apoptosis and inflammation via the NF-κB and MAPK signaling pathways in rat chondrocytes and ameliorates osteoarthritisin vivo.
Teng L, Shen Y, Qu Y, Yang L, Yang Y, Jian X, Fan S, Zhang L, Fu Q
Chinese journal of natural medicines 2023 Feb;21(2):99-112
Chinese journal of natural medicines 2023 Feb;21(2):99-112
FNDC5/Irisin Inhibits the Inflammatory Response and Mediates the Aerobic Exercise-Induced Improvement of Liver Injury after Myocardial Infarction.
Wang T, Yu M, Li H, Qin S, Ren W, Ma Y, Bo W, Xi Y, Cai M, Tian Z
International journal of molecular sciences 2023 Feb 19;24(4)
International journal of molecular sciences 2023 Feb 19;24(4)
CXCL chemokines-mediated communication between macrophages and BMSCs on titanium surface promotes osteogenesis via the actin cytoskeleton pathway.
Zhang Y, Wei J, Yu X, Chen L, Ren R, Dong Y, Wang S, Zhu M, Ming N, Zhu Z, Gao C, Xiong W
Materials today. Bio 2023 Dec;23:100816
Materials today. Bio 2023 Dec;23:100816
Quercetin improves cerebral ischemia/reperfusion injury by promoting microglia/macrophages M2 polarization via regulating PI3K/Akt/NF-κB signaling pathway.
Li L, Jiang W, Yu B, Liang H, Mao S, Hu X, Feng Y, Xu J, Chu L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec;168:115653
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec;168:115653
Red Cabbage Juice-Mediated Gut Microbiota Modulation Improves Intestinal Epithelial Homeostasis and Ameliorates Colitis.
Jean Wilson E, Sirpu Natesh N, Ghadermazi P, Pothuraju R, Prajapati DR, Pandey S, Kaifi JT, Dodam JR, Bryan JN, Lorson CL, Watrelot AA, Foster JM, Mansell TJ, Joshua Chan SH, Batra SK, Subbiah J, Rachagani S
International journal of molecular sciences 2023 Dec 30;25(1)
International journal of molecular sciences 2023 Dec 30;25(1)
Inducible nitric oxide synthase (iNOS)-activated Cxcr2 signaling in myeloid cells promotes TGFβ-dependent squamous cell carcinoma lung metastasis.
Li X, Ke Y, Hernandez AL, Yu J, Bian L, Hall SC, Nolan K, Wang JH, Young CD, Wang XJ
Cancer letters 2023 Aug 28;570:216330
Cancer letters 2023 Aug 28;570:216330
Red cabbage juice-mediated gut microbiota modulation improves intestinal epithelial homeostasis and ameliorates colitis.
Jean Wilson E, Sirpu Natesh N, Ghadermazi P, Pothuraju R, Shanmugam M, Prajapati DR, Pandey S, Kaifi JT, Dodam JR, Bryan J, Lorson CL, Watrelot AA, Foster JM, Mansel TJ, Joshua Chan SH, Batra SK, Subbiah J, Rachagani S
bioRxiv : the preprint server for biology 2023 Aug 24;
bioRxiv : the preprint server for biology 2023 Aug 24;
Injectable photocrosslinking spherical hydrogel-encapsulated targeting peptide-modified engineered exosomes for osteoarthritis therapy.
Wan J, He Z, Peng R, Wu X, Zhu Z, Cui J, Hao X, Chen A, Zhang J, Cheng P
Journal of nanobiotechnology 2023 Aug 21;21(1):284
Journal of nanobiotechnology 2023 Aug 21;21(1):284
Irisin attenuates acute lung injury by suppressing the pyroptosis of alveolar macrophages.
Han Z, Ma J, Han Y, Yuan G, Jiao R, Meng A
International journal of molecular medicine 2023 Apr;51(4)
International journal of molecular medicine 2023 Apr;51(4)
Wei-Tong-Xin exerts anti-inflammatory effects through TLR4-mediated macrophages M1/M2 polarization and affects GLP-1 secretion.
Zhang X, Yang X, Zhang S, Wang J, Wang M, Ma T, Wan M, Lv X, Yan T, Jia Y
The Journal of pharmacy and pharmacology 2023 Apr 7;75(4):574-584
The Journal of pharmacy and pharmacology 2023 Apr 7;75(4):574-584
Glucose Transporter Glut1-Dependent Metabolic Reprogramming Regulates Lipopolysaccharide-Induced Inflammation in RAW264.7 Macrophages.
Cornwell A, Ziółkowski H, Badiei A
Biomolecules 2023 Apr 29;13(5)
Biomolecules 2023 Apr 29;13(5)
Synthesis of Lathyrol PROTACs and Evaluation of Their Anti-Inflammatory Activities.
Wang W, Liu Y, Xiong L, Sun D, Wang H, Song Z, Li Y, Li H, Chen L
Journal of natural products 2023 Apr 28;86(4):767-781
Journal of natural products 2023 Apr 28;86(4):767-781
Concentrated growth factor combined with iRoot BP Plus promotes inflamed pulp repair: an in vitro and in vivo study.
Zeng Q, Zhou C, Li M, Qiu Y, Wei X, Liu H
BMC oral health 2023 Apr 19;23(1):225
BMC oral health 2023 Apr 19;23(1):225
Betaine Inhibits NLRP3 Inflammasome Hyperactivation and Regulates Microglial M1/M2 Phenotypic Differentiation, Thereby Attenuating Lipopolysaccharide-Induced Depression-Like Behavior.
Zhang M, Wang XL, Shi H, Meng LQ, Quan HF, Yan L, Yang HF, Peng XD
Journal of immunology research 2022;2022:9313436
Journal of immunology research 2022;2022:9313436
Comparison of Three Species of Rhubarb in Inhibiting Vascular Endothelial Injury via Regulation of PI3K/AKT/NF-κB Signaling Pathway.
Li X, Huang S, Zhuo B, Hu J, Shi Y, Zhao J, Tang J, Hu X, Wei S
Oxidative medicine and cellular longevity 2022;2022:8979329
Oxidative medicine and cellular longevity 2022;2022:8979329
Inhibiting Sphingosine 1-Phosphate Receptor Subtype 3 Attenuates Brain Damage During Ischemia-Reperfusion Injury by Regulating nNOS/NO and Oxidative Stress.
Fan X, Chen H, Xu C, Wang Y, Yin P, Li M, Tang Z, Jiang F, Wei W, Song J, Li G, Zhong D
Frontiers in neuroscience 2022;16:838621
Frontiers in neuroscience 2022;16:838621
Novel recombinant protein flagellin A N/C attenuates experimental autoimmune encephalomyelitis by suppressing the ROS/NF-κB/NLRP3 signaling pathway.
Li L, Deng S, Liu M, Yang M, Li J, Liu T, Zhang T, Zhao Y, He M, Wu D, Xu Y
Frontiers in pharmacology 2022;13:956402
Frontiers in pharmacology 2022;13:956402
Single-cell RNA sequencing reveals distinct immunology profiles in human keloid.
Feng C, Shan M, Xia Y, Zheng Z, He K, Wei Y, Song K, Meng T, Liu H, Hao Y, Liang Z, Wang Y, Huang Y
Frontiers in immunology 2022;13:940645
Frontiers in immunology 2022;13:940645
Cassane diterpenoid ameliorates dextran sulfate sodium-induced experimental colitis by regulating gut microbiota and suppressing tryptophan metabolism.
Liu T, Ning Z, Liu P, Gao H
Frontiers in immunology 2022;13:1045901
Frontiers in immunology 2022;13:1045901
Isoalantolactone (IAL) Regulates Neuro-Inflammation and Neuronal Apoptosis to Curb Pathology of Parkinson's Disease.
He D, Liu Y, Li J, Wang H, Ye B, He Y, Li Z, Gao X, Fu S, Liu D
Cells 2022 Sep 19;11(18)
Cells 2022 Sep 19;11(18)
Macrophage-derived extracellular vesicles regulate follicular activation and improve ovarian function in old mice by modulating local environment.
Xiao Y, Peng X, Peng Y, Zhang C, Liu W, Yang W, Dou X, Jiang Y, Wang Y, Yang S, Xiang W, Wu T, Li J
Clinical and translational medicine 2022 Oct;12(10):e1071
Clinical and translational medicine 2022 Oct;12(10):e1071
Eupalinolide B attenuates lipopolysaccharide-induced acute lung injury through inhibition of NF-κB and MAPKs signaling by targeting TAK1 protein.
Yang L, Chen H, Hu Q, Liu L, Yuan Y, Zhang C, Tang J, Shen X
International immunopharmacology 2022 Oct;111:109148
International immunopharmacology 2022 Oct;111:109148
Fecal microbiota transplantation from young donor mice improves ovarian function in aged mice.
Xu L, Zhang Q, Dou X, Wang Y, Wang J, Zhou Y, Liu X, Li J
Journal of genetics and genomics = Yi chuan xue bao 2022 Nov;49(11):1042-1052
Journal of genetics and genomics = Yi chuan xue bao 2022 Nov;49(11):1042-1052
Extracellular vesicles from human urine-derived stem cells merged in hyaluronic acid ameliorate erectile dysfunction in type 2 diabetic rats by glans administration.
Zhuang J, Gao P, Chen H, Fang Z, Zheng J, Zhu D, Hou J
Andrology 2022 Nov;10(8):1673-1686
Andrology 2022 Nov;10(8):1673-1686
Oxybaphus himalaicus Mitigates Lipopolysaccharide-Induced Acute Kidney Injury by Inhibiting TLR4/MD2 Complex Formation.
Zhan H, Pu Q, Long X, Lu W, Wang G, Meng F, Liao Z, Lan X, Chen M
Antioxidants (Basel, Switzerland) 2022 Nov 22;11(12)
Antioxidants (Basel, Switzerland) 2022 Nov 22;11(12)
Galectin-3 regulates microglial activation and promotes inflammation through TLR4/MyD88/NF-kB in experimental autoimmune uveitis.
Liu Y, Zhao C, Meng J, Li N, Xu Z, Liu X, Hou S
Clinical immunology (Orlando, Fla.) 2022 Mar;236:108939
Clinical immunology (Orlando, Fla.) 2022 Mar;236:108939
The circadian clock protein Rev-erbα provides neuroprotection and attenuates neuroinflammation against Parkinson's disease via the microglial NLRP3 inflammasome.
Kou L, Chi X, Sun Y, Han C, Wan F, Hu J, Yin S, Wu J, Li Y, Zhou Q, Zou W, Xiong N, Huang J, Xia Y, Wang T
Journal of neuroinflammation 2022 Jun 6;19(1):133
Journal of neuroinflammation 2022 Jun 6;19(1):133
Apelin alleviated neuroinflammation and promoted endogenous neural stem cell proliferation and differentiation after spinal cord injury in rats.
Liu Q, Zhou S, Wang X, Gu C, Guo Q, Li X, Zhang C, Zhang N, Zhang L, Huang F
Journal of neuroinflammation 2022 Jun 20;19(1):160
Journal of neuroinflammation 2022 Jun 20;19(1):160
Salubrinal protects against inflammatory response in macrophage and attenuates psoriasiform skin inflammation by antagonizing NF-κB signaling pathway.
Shangguan Y, Chen Y, Ma Y, Zhao Y, He Y, Li W
Biochemical and biophysical research communications 2022 Jan 22;589:63-70
Biochemical and biophysical research communications 2022 Jan 22;589:63-70
Tamoxifen Exerts Anticancer Effects on Pituitary Adenoma Progression via Inducing Cell Apoptosis and Inhibiting Cell Migration.
Lv T, Zhang Z, Yu H, Ren S, Wang J, Li S, Sun L
International journal of molecular sciences 2022 Feb 28;23(5)
International journal of molecular sciences 2022 Feb 28;23(5)
Glabridin inhibits liver fibrosis and hepatic stellate cells activation through suppression of inflammation and oxidative stress by activating PPARγ in carbon tetrachloride-treated mice.
Zhang L, Zhang H, Gu J, Xu W, Yuan N, Sun J, Li H
International immunopharmacology 2022 Dec;113(Pt B):109433
International immunopharmacology 2022 Dec;113(Pt B):109433
Epoxymicheliolide prevents dextran sulfate sodium-induced colitis in mice by inhibiting TAK1-NF-κB pathway and activating Keap1-NRF2 signaling in macrophages.
He J, Liu L, Liu X, Chen H, Liu K, Huang N, Wang Y
International immunopharmacology 2022 Dec;113(Pt A):109404
International immunopharmacology 2022 Dec;113(Pt A):109404
Burdock (Arctium lappa L.) leaf flavonoids rich in morin and quercetin 3-O-rhamnoside ameliorate lipopolysaccharide-induced inflammation and oxidative stress in RAW264.7 cells.
Cui J, Zong W, Zhao N, Yuan R
Food science & nutrition 2022 Aug;10(8):2718-2726
Food science & nutrition 2022 Aug;10(8):2718-2726
The licorice flavonoid isoliquiritigenin attenuates Mycobacterium tuberculosis-induced inflammation through Notch1/NF-κB and MAPK signaling pathways.
Sun J, Zhang Q, Yang G, Li Y, Fu Y, Zheng Y, Jiang X
Journal of ethnopharmacology 2022 Aug 10;294:115368
Journal of ethnopharmacology 2022 Aug 10;294:115368
The alleviative effect of flavonol-type Nrf2 activator rhamnazin from Physalis alkekengi L. var. franchetii (Mast.) Makino on pulmonary disorders.
Wu XY, Wang T, Hu HX, Zhang K, Zhao Y, Zhao BB, Lou HX, Wang XN, Shen T
Phytotherapy research : PTR 2022 Apr;36(4):1692-1707
Phytotherapy research : PTR 2022 Apr;36(4):1692-1707
Limonin Inhibits IL-1β-Induced Inflammation and Catabolism in Chondrocytes and Ameliorates Osteoarthritis by Activating Nrf2.
Jin J, Lv X, Wang B, Ren C, Jiang J, Chen H, Chen X, Gu M, Pan Z, Tian N, Wu A, Sun L, Gao W, Wang X, Zhang X, Wu Y, Zhou Y
Oxidative medicine and cellular longevity 2021;2021:7292512
Oxidative medicine and cellular longevity 2021;2021:7292512
Targeting Myadm to Intervene Pulmonary Hypertension on Rats Before Pregnancy Alleviates the Effect on Their Offspring's Cardiac-Cerebral Systems.
Wang J, Zhang Z, Liang C, Lv T, Yu H, Ren S, Lin P, Du G, Sun L
Frontiers in pharmacology 2021;12:791370
Frontiers in pharmacology 2021;12:791370
Spinal Nrf2 translocation may inhibit neuronal NF-κB activation and alleviate allodynia in a rat model of bone cancer pain.
Fu J, Ni C, Ni HD, Xu LS, He QL, Pan H, Huang DD, Sun YB, Luo G, Liu MJ, Yao M
Journal of neurochemistry 2021 Sep;158(5):1110-1130
Journal of neurochemistry 2021 Sep;158(5):1110-1130
Sulforaphane alleviates hyperalgesia and enhances analgesic potency of morphine in rats with cancer-induced bone pain.
Fu J, Xu M, Xu L, Ni H, Zhao B, Ni C, Huang M, Zhu J, Luo G, Yao M
European journal of pharmacology 2021 Oct 15;909:174412
European journal of pharmacology 2021 Oct 15;909:174412
Proto-oncogene tyrosine-protein kinase SRC (Src) inhibition in microglia relieves neuroinflammation in neuropathic pain mouse models.
Cai Y, Xu J, Cheng Q
Bioengineered 2021 Dec;12(2):11390-11398
Bioengineered 2021 Dec;12(2):11390-11398
CGRP-Mediated Prolactin Upregulation: a Possible Pathomechanism in IgG4-Related Disease.
Liu Q, Lin Y, Zhang S, Chen M, Chen Q, Rui H, Wang F, Lv X, Gao F
Inflammation 2021 Apr;44(2):536-548
Inflammation 2021 Apr;44(2):536-548
Weak Ultraviolet B Enhances the Mislocalization of Claudin-1 Mediated by Nitric Oxide and Peroxynitrite Production in Human Keratinocyte-Derived HaCaT Cells.
Kobayashi M, Shu S, Marunaka K, Matsunaga T, Ikari A
International journal of molecular sciences 2020 Sep 27;21(19)
International journal of molecular sciences 2020 Sep 27;21(19)
Protective effects and potential mechanism of salvianolic acid B on sodium laurate-induced thromboangiitis obliterans in rats.
Zhang Z, Ji J, Zhang D, Ma M, Sun L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2020 Jan;66:153110
Phytomedicine : international journal of phytotherapy and phytopharmacology 2020 Jan;66:153110
Geniposide attenuates Aβ(25-35)-induced neurotoxicity via the TLR4/NF-κB pathway in HT22 cells.
Huang XF, Li JJ, Tao YG, Wang XQ, Zhang RL, Zhang JL, Su ZQ, Huang QH, Deng YH
RSC advances 2018 May 22;8(34):18926-18937
RSC advances 2018 May 22;8(34):18926-18937
No comments: Submit comment
No validations: Submit validation data