Antibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
Reference
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- Product number
- 18395-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#18395-1-AP, RRID:AB_2286622
- Product name
- SLN antibody
- Antibody type
- Polyclonal
- Description
- SLN antibody (Cat. #18395-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references (-)-epicatechin treatment did not modify the thermogenic pathway in the gastrocnemius muscle of male rat offspring obeses by programming.
Skeletal muscle overexpression of sAnk1.5 in transgenic mice does not predispose to type 2 diabetes.
Maternal exercise intergenerationally drives muscle-based thermogenesis via activation of apelin-AMPK signaling.
A Temporal Examination of Cytoplasmic Ca(2 +) Levels, Sarcoplasmic Reticulum Ca(2 +) Levels, and Ca(2 +) -Handling-Related Proteins in Different Skeletal Muscles of Hibernating Daurian Ground Squirrels.
ChREBP-β regulates thermogenesis in brown adipose tissue.
Effect of sarcolipin-mediated cell transdifferentiation in sarcopenia-associated skeletal muscle fibrosis.
Sarcolipin expression is repressed by endoplasmic reticulum stress in C2C12 myotubes.
Interactions between small ankyrin 1 and sarcolipin coordinately regulate activity of the sarco(endo)plasmic reticulum Ca(2+)-ATPase (SERCA1).
Ca(2+) permeation and/or binding to CaV1.1 fine-tunes skeletal muscle Ca(2+) signaling to sustain muscle function.
Identification of Small Ankyrin 1 as a Novel Sarco(endo)plasmic Reticulum Ca2+-ATPase 1 (SERCA1) Regulatory Protein in Skeletal Muscle.
Tejeda ME, De Los Santos S, Coral-Vázquez RM, Álvarez-Chávez A, Palma Flores C, Zambrano E, Méndez JP, Canto P
Journal of developmental origins of health and disease 2024 Mar 19;15:e4
Journal of developmental origins of health and disease 2024 Mar 19;15:e4
Skeletal muscle overexpression of sAnk1.5 in transgenic mice does not predispose to type 2 diabetes.
Pierantozzi E, Raucci L, Buonocore S, Rubino EM, Ding Q, Laurino A, Fiore F, Soldaini M, Chen J, Rossi D, Vangheluwe P, Chen H, Sorrentino V
Scientific reports 2023 May 20;13(1):8195
Scientific reports 2023 May 20;13(1):8195
Maternal exercise intergenerationally drives muscle-based thermogenesis via activation of apelin-AMPK signaling.
Son JS, Chae SA, Zhao L, Wang H, de Avila JM, Zhu MJ, Jiang Z, Du M
EBioMedicine 2022 Feb;76:103842
EBioMedicine 2022 Feb;76:103842
A Temporal Examination of Cytoplasmic Ca(2 +) Levels, Sarcoplasmic Reticulum Ca(2 +) Levels, and Ca(2 +) -Handling-Related Proteins in Different Skeletal Muscles of Hibernating Daurian Ground Squirrels.
Wang Z, Zhang J, Ma XF, Chang H, Peng X, Xu SH, Wang HP, Gao YF
Frontiers in physiology 2020;11:562080
Frontiers in physiology 2020;11:562080
ChREBP-β regulates thermogenesis in brown adipose tissue.
Wei C, Ma X, Su K, Qi S, Zhu Y, Lin J, Wang C, Yang R, Chen X, Wang W, Zhang WJ
The Journal of endocrinology 2020 Jun;245(3):343-356
The Journal of endocrinology 2020 Jun;245(3):343-356
Effect of sarcolipin-mediated cell transdifferentiation in sarcopenia-associated skeletal muscle fibrosis.
Chen QN, Fan Z, Lyu AK, Wu J, Guo A, Yang YF, Chen JL, Xiao Q
Experimental cell research 2020 Apr 1;389(1):111890
Experimental cell research 2020 Apr 1;389(1):111890
Sarcolipin expression is repressed by endoplasmic reticulum stress in C2C12 myotubes.
Takahashi N, Kimura AP, Naito S, Yoshida M, Kumano O, Suzuki T, Itaya S, Moriya M, Tsuji M, Ieko M
Journal of physiology and biochemistry 2017 Nov;73(4):531-538
Journal of physiology and biochemistry 2017 Nov;73(4):531-538
Interactions between small ankyrin 1 and sarcolipin coordinately regulate activity of the sarco(endo)plasmic reticulum Ca(2+)-ATPase (SERCA1).
Desmond PF, Labuza A, Muriel J, Markwardt ML, Mancini AE, Rizzo MA, Bloch RJ
The Journal of biological chemistry 2017 Jun 30;292(26):10961-10972
The Journal of biological chemistry 2017 Jun 30;292(26):10961-10972
Ca(2+) permeation and/or binding to CaV1.1 fine-tunes skeletal muscle Ca(2+) signaling to sustain muscle function.
Lee CS, Dagnino-Acosta A, Yarotskyy V, Hanna A, Lyfenko A, Knoblauch M, Georgiou DK, Poché RA, Swank MW, Long C, Ismailov II, Lanner J, Tran T, Dong K, Rodney GG, Dickinson ME, Beeton C, Zhang P, Dirksen RT, Hamilton SL
Skeletal muscle 2015;5:4
Skeletal muscle 2015;5:4
Identification of Small Ankyrin 1 as a Novel Sarco(endo)plasmic Reticulum Ca2+-ATPase 1 (SERCA1) Regulatory Protein in Skeletal Muscle.
Desmond PF, Muriel J, Markwardt ML, Rizzo MA, Bloch RJ
The Journal of biological chemistry 2015 Nov 13;290(46):27854-67
The Journal of biological chemistry 2015 Nov 13;290(46):27854-67
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human heart tissue were subjected to SDS PAGE followed by western blot with 18395-1-AP(SLN antibody) at dilution of 1:300
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human heart using 18395-1-AP(SLN antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The SLN antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human SLN. This antibody recognizes human,mouse,rat antigen. The SLN antibody has been validated for the following applications: ELISA, WB, IHC analysis.