Explore
Validate
Learn
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [13]
- Comments [0]
- Validations
- Western blot [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 10430-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10430-1-AP, RRID:AB_2078859
- Product name
- CDK5 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated CDK5 antibody (Cat. #10430-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references FBXO22 is a potential therapeutic target for recurrent chondrosarcoma.
Electroacupuncture ameliorates chronic unpredictable mild stress-induced depression-like behavior and cognitive impairment through suppressing oxidative stress and neuroinflammation in rats.
The γ-Adducin 1-357 fragment promotes tau pathology.
Rac is required for the survival of cortical neurons.
Highly effective identification of drug targets at the proteome level by pH-dependent protein precipitation.
The LPA-CDK5-tau pathway mediates neuronal injury in an in vitro model of ischemia-reperfusion insult.
Phosphorylation-Induced Ubiquitination and Degradation of PXR through CDK2-TRIM21 Axis.
SARS-CoV-2 hijacks cellular kinase CDK2 to promote viral RNA synthesis.
Hypoxia induces HT-22 neuronal cell death via Orai1/CDK5 pathway-mediated Tau hyperphosphorylation.
Ginsenoside compound K ameliorates Alzheimer's disease in HT22 cells by adjusting energy metabolism.
Potent effects of dioscin against hepatocellular carcinoma through regulating TP53-induced glycolysis and apoptosis regulator (TIGAR)-mediated apoptosis, autophagy, and DNA damage.
Inhibition of Cdk5 rejuvenates inhibitory circuits and restores experience-dependent plasticity in adult visual cortex.
Nestin protects mouse podocytes against high glucose-induced apoptosis by a Cdk5-dependent mechanism.
Xin B, Chen H, Zhu Z, Guan Q, Bai G, Yang C, Zou W, Gao X, Li L, Liu T
Journal of bone oncology 2024 Jun;46:100605
Journal of bone oncology 2024 Jun;46:100605
Electroacupuncture ameliorates chronic unpredictable mild stress-induced depression-like behavior and cognitive impairment through suppressing oxidative stress and neuroinflammation in rats.
Tong T, Hao C, Shen J, Liu S, Yan S, Aslam MS, Chen Y, Chen W, Li J, Li Y, Zeng J, Li M, You Z, Gulizhaerkezi T, Wei S, Zhu A, Meng X
Brain research bulletin 2024 Jan;206:110838
Brain research bulletin 2024 Jan;206:110838
The γ-Adducin 1-357 fragment promotes tau pathology.
Yu H, Xiong M, Liu C, Xia D, Meng L, Zhang Z
Frontiers in aging neuroscience 2023;15:1241750
Frontiers in aging neuroscience 2023;15:1241750
Rac is required for the survival of cortical neurons.
Katayama KI, Zheng Y, Inoue N
Experimental neurology 2023 Mar;361:114316
Experimental neurology 2023 Mar;361:114316
Highly effective identification of drug targets at the proteome level by pH-dependent protein precipitation.
Zhang X, Wang K, Wu S, Ruan C, Li K, Wang Y, Zhu H, Liu X, Liu Z, Li G, Hu L, Ye M
Chemical science 2022 Nov 2;13(42):12403-12418
Chemical science 2022 Nov 2;13(42):12403-12418
The LPA-CDK5-tau pathway mediates neuronal injury in an in vitro model of ischemia-reperfusion insult.
Wang Y, Zhang J, Huang L, Mo Y, Wang C, Li Y, Zhang Y, Zhang Z
BMC neurology 2022 May 2;22(1):166
BMC neurology 2022 May 2;22(1):166
Phosphorylation-Induced Ubiquitination and Degradation of PXR through CDK2-TRIM21 Axis.
Qin M, Xin Y, Bian Y, Yang X, Xi T, Xiong J
Cells 2022 Jan 13;11(2)
Cells 2022 Jan 13;11(2)
SARS-CoV-2 hijacks cellular kinase CDK2 to promote viral RNA synthesis.
Guo S, Lei X, Chang Y, Zhao J, Wang J, Dong X, Liu Q, Zhang Z, Wang L, Yi D, Ma L, Li Q, Zhang Y, Ding J, Liang C, Li X, Guo F, Wang J, Cen S
Signal transduction and targeted therapy 2022 Dec 27;7(1):400
Signal transduction and targeted therapy 2022 Dec 27;7(1):400
Hypoxia induces HT-22 neuronal cell death via Orai1/CDK5 pathway-mediated Tau hyperphosphorylation.
Fang B, Zhao Q, Ling W, Zhang Y, Ou M
American journal of translational research 2019;11(12):7591-7603
American journal of translational research 2019;11(12):7591-7603
Ginsenoside compound K ameliorates Alzheimer's disease in HT22 cells by adjusting energy metabolism.
Chen X, Li H, Yang Q, Lan X, Wang J, Cao Z, Shi X, Li J, Kan M, Qu X, Li N
Molecular biology reports 2019 Oct;46(5):5323-5332
Molecular biology reports 2019 Oct;46(5):5323-5332
Potent effects of dioscin against hepatocellular carcinoma through regulating TP53-induced glycolysis and apoptosis regulator (TIGAR)-mediated apoptosis, autophagy, and DNA damage.
Mao Z, Han X, Chen D, Xu Y, Xu L, Yin L, Sun H, Qi Y, Fang L, Liu K, Peng J
British journal of pharmacology 2019 Apr;176(7):919-937
British journal of pharmacology 2019 Apr;176(7):919-937
Inhibition of Cdk5 rejuvenates inhibitory circuits and restores experience-dependent plasticity in adult visual cortex.
Li Y, Wang L, Zhang X, Huang M, Li S, Wang X, Chen L, Jiang B, Yang Y
Neuropharmacology 2018 Jan;128:207-220
Neuropharmacology 2018 Jan;128:207-220
Nestin protects mouse podocytes against high glucose-induced apoptosis by a Cdk5-dependent mechanism.
Liu W, Zhang Y, Hao J, Liu S, Liu Q, Zhao S, Shi Y, Duan H
Journal of cellular biochemistry 2012 Oct;113(10):3186-96
Journal of cellular biochemistry 2012 Oct;113(10):3186-96
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The CDK5 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human CDK5. This antibody recognizes human, mouse, rat antigen. The CDK5 antibody has been validated for the following applications: ELISA, WB analysis.
