Explore
Validate
Learn
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [1792]
- Comments [0]
- Validations
- Western blot [1]
- Immunoprecipitation [1]
- Flow cytometry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 22018-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- N-cadherin antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated N-cadherin antibody (Cat. #22018-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references A novel Nilotinib derivative N-12 inhibits the proliferation and migration of colon cancer cells through the EMT signaling pathway.
THBS3 Functions as a Novel Biomarker for Prognosis and Immunotherapeutic Response in Colorectal Cancer: An Integrative Analysis and Validation of the Thrombospondin Gene Family.
Yifei Decoction Regulates the NGF/TRKA/PI3K/AKT Signaling Axis to Inhibit the Epithelial-Mesenchymal Transformation and Proliferation of Pulmonary Epithelial Cells in Bleomycin-Induced Pulmonary Fibrogenesis.
GNPAT promotes immunosuppression in hepatocellular carcinoma by activating the plasmalogen-PPARγ pathway to drive M2 macrophage polarization.
Targeting CPS1 attenuates lung cancer metastasis by regulating EMT through an epigenetic mechanism.
A novel mouse cell line model reveals the tumor intrinsic and immune characteristics of EGFR-mutant lung cancer.
Macrophage-Derived Transcriptional Signatures Predict Prognosis and Drug Sensitivity in Thyroid Cancer: Integrative Analysis and Experimental Validation of SMYD3.
ESRP1 drives epithelial-mesenchymal transition by activating EPAC-RAP1A signaling axis.
Endothelial SMAD1-MCAM axis facilitates sunitinib resistance and progression of clear cell renal cell carcinoma via LAMB1-ITGB1 signaling.
ATP-binding cassette subfamily A member 5 suppresses pancreatic ductal adenocarcinoma progression and chemoresistance by promoting β-catenin ubiquitin-dependent degradation.
PLOD2 Promotes Cutaneous Squamous Cell Carcinoma Progression in Association With STAT3-Related ERK and AKT Pathways.
A promising magnesium-related alloy with metabolic reprogramming and antitumor effects in hepatocellular and pancreatic cancer.
Plasmin promotes hepatocellular carcinoma invasion and metastasis via CXCR4-mediated activation of PI3K/AKT/mTOR signaling.
Development of a self-assembling aggregation-induced emission nanoprobe for targeted therapy and real-time imaging in non-small cell lung cancer.
Peroxiredoxin 4 suppresses ferroptosis in esophageal squamous cell carcinoma by activating the phosphoinositide 3-kinase signaling pathway.
m⁶A-modified circMELK regulates nasopharyngeal carcinoma progression via a YTHDF1/circMELK-miR-4775-HMGA2 feedback loop.
Multi-omics analysis and preliminary experimental validation of acetyl tributyl citrate (ATBC) promoting bladder cancer progression via the AKR1B1/EMT axis.
Prenylterphenyllin, a regulator of P53, inhibits colorectal cancer progression through oxidative stress and energy metabolism pathway.
ENO1 inhibition synergizes with chidamide to induce ferroptosis in PTCL-NOS through metabolic remodeling.
Oncogenic role of talin-1 in glioma: Association with poor prognosis and regulation of the TGF-beta signaling pathway.
Nobiletin and polydatin synergistically alleviate triple-negative breast cancer liver metastasis via suppressing ECM1a-mediated fatty acid biosynthesis.
Promotion of hepatocellular carcinoma by small nuclear ribonucleoprotein polypeptide F through upregulation of transmembrane P24 trafficking protein 2 and triggering of the cGAS-STING pathway.
Novel nanoparticle-combined therapy through EGFR and PD-L1 blockade: PFPR-siRNA-mediated suppressing NSCLC proliferation via PDT and enhanced antitumor immunity.
AURKA Activates FOXO3a to Form a Positive Feedback Loop in the Proliferation and Migration of Keloid Fibroblasts.
TRIM35 inhibits endometrial cancer progression via ubiquitination and degradation of EIF3E.
ANO6 Confers Paclitaxel Resistance by Targeting Ferroptosis in Cervical Cancer.
PIEZO1 enhances pancreatic cancer neurotropism.
Kukoamine B Inhibits EMT in Lung Adenocarcinoma Cells by Regulating Intracellular PD-L1-Mediated p65 Nuclear Translocation.
TWIST1-Mediated Induction of AEBP1 in Fibroblast-Like Synoviocytes Activates Transforming Growth Factor β Signaling to Drive Angiogenesis and Promote Rheumatoid Arthritis.
Activation of the PI3K/AKT pathway by EDIL3 induces EMT and promotes tumor progression in clear cell renal cell carcinoma.
TFAP2A regulates SGPP2 transcription to promote lipid accumulation and activate the Wnt/β-catenin signaling pathway to promote malignant progression in lung adenocarcinoma.
Multi-omics analysis of NEDD1 in hepatocellular carcinoma: biological function, prognostic value, and clinical significance.
Mechanism of LPS-activated gingival fibroblasts promote the migration of gastric cancer cells via CXCL12/CXCR4-Snail2-EMT axis.
Mechanistic study of miR-486-5p targeting Claudin-10 in placenta accreta spectrum pathogenesis and its impact on trophoblast behavior.
Tannic Acid Inhibits Lung Adenocarcinoma Progression by Suppressing MMP-2-Mediated Epithelial-Mesenchymal Transition.
The APC/C subunit APC7 promotes hepatocellular carcinoma progression by mediating ubiquitination and degradation of LATS1 to activate YAP/TAZ.
USP1 promotes hepatocellular carcinoma progression by modulating mitophagy via stabilizing MCM3 to regulate the Keap1-Nrf2 axis.
USP5-mediated CD73 deubiquitination drives osimertinib resistance via PI3K/AKT and glycolysis activation in LUAD.
SGK1 Is Upregulated in Retained Placenta and Mediates Estradiol Effects in Bovine Endometrial Cells.
FUT8 reprograms glycolytic metabolism to promote PKM2 lactylation and drive clear cell renal cell carcinoma progression.
Omics insights into MYBL2-promoted cancer stem-like cells driving ferroptosis resistance in hepatocellular carcinoma.
B3GNT3 facilitates NFKB2 processing and non-canonical NF-κB activation to drive lung adenocarcinoma progression.
RRP9 suppresses hepatocellular carcinoma progression by inhibiting the PI3K/AKT/mTOR pathway.
Mechanism of HAND2 Regulating Glycolytic Metabolism and Metastasis Through TLR4/NOX2/DUOX2 Signaling Axis in Cervical Cancer.
TAOK3 promotes ccRCC progression by phosphorylating ASAP2.
Syntaphilin inhibits glioma invasion via modulating mitochondria redistribution and shapes the immune microenvironment: A potential prognostic biomarker.
IGHG1(+) malignant epithelial Cell-myCAF crosstalk via MIF-CD74/APP-CD74 drives early brain metastasis in NSCLC: Delineated via primary tumor-brain metastasis single-cell and spatial transcriptomics.
AEG-1 3'UTR functions as a ceRNA to facilitate Helicobacter pylori-induced gastric cancer EMT by regulating the miR-375-3p/JAK2 axis.
A positive SPTBN2-FLI1 feedback axis promotes bladder cancer via PI3K/AKT activation.
Targeting the NR5A1-KISS1R-EMT axis with a small-molecule inhibitor suppresses lung adenocarcinoma progression and metastasis.
GLT8D2-mediated PD-L1 N-glycosylation promotes tumor immune evasion in ovarian cancer peritoneal metastasis.
piR-43452 suppresses bladder cancer progression and enhances gemcitabine sensitivity via GTSF1/PIWIL4-mediated LRP1 mRNA destabilization.
TRIM32 promotes anoikis resistance and metastasis in NSCLC by degrading CHEK2 to enhance IL-6 secretion.
Calcitonin gene-related peptide inhibits macrophage migration and differentiation via the GTPase Rap1.
Downregulation of BST2 Rescues Cochlear Nerve Demyelination in Age-Related Hearing Loss via Enhancing Schwann Cell Migration.
The α5-nAChR/GINS4 axis contributed to nicotine-promoted lung adenocarcinoma progression.
Silence of circPLK1 inhibits NSCLC progression by regulating the miR-1294/SLC16A9 axis.
CypA Mediates Non-Small Cell Lung Cancer Chemoresistance by Attenuating Ferroptosis via Stabilizing SLC7A11.
SIGLEC15 modulates the immunosuppressive microenvironment and suppresses malignant phenotypes in triple-negative breast cancer.
NAT10-mediated ac4C modifications regulate glioblastoma progression.
Integrating single cell- and spatial- resolved transcriptomics unravels the inter-tumor heterogeneity and immunosuppressive landscape in HBV- and Clonorchis sinensis-associated hepatocellular carcinoma.
EIF4A3/circPTGR1/miR-4725-5p positive- feedback loop promotes colorectal cancer progression via FAK/AKT signaling pathway.
PPIA regulates fatty acid and glutamine metabolism in lung adenocarcinoma based on multiomics prognostic model and experiment validation.
SCHEMBL4796824: a multifaceted antitumor agent targeting microtubule dynamics, DNA damage, and Wnt/β-catenin signaling in ovarian cancer cells.
CircCCDC66 promotes the progression and EMT of renal cell carcinoma via the miR-1278/HOXA13 axis.
SULT1E1 exerts a protective role in COPD by inhibiting the AKT pathway: an in vivo and in vitro study.
SPIB suppresses protective autophagy via the IFIT2/PINK1/Parkin axis to promote anoikis in colorectal cancer.
KIN17 facilitates the initiation and progression of renal tumor progression through the PI3K-AKT-mTOR pathway.
HOXB4 Promotes Bladder Cancer Progression in Part Through Transcriptional Activation of Smoothened.
Methylation-induced silencing of AZGP1 enhances prostate cancer metastasis by stimulating tumoral glycolysis.
Cuproptosis of bronchial epithelial cells triggers airway remodeling in chronic asthma.
Linarin Suppresses the Progression of Colorectal Cancer by Inhibiting the HIF-1α/PD-L1 Axis.
CIAPIN1 as a Promoter of Oral Squamous Cell Carcinoma Progression.
COL1A1 promotes clear cell renal cell carcinoma progression through the Wnt/β-catenin signaling pathway.
DLGAP5 regulates malignancy and lenvatinib sensitivity of hepatocellular carcinoma through AKT/mTOR/NF-κB pathway.
Interleukin-7 induces EMT to promote tumor growth and metastasis in NSCLC via Notch1/TGF-β pathway.
VAMP7 governs ferroptosis suppression and cisplatin resistance in esophageal cancer: a dual-targeting therapeutic paradigm.
Targeting TFAM K76 acetylation attenuates mitochondrial dysfunction and kidney injury in diabetic kidney disease.
Fibroblast Growth Factor 11 Improves Fertility by Alleviating Intrauterine Adhesionss in Rats Through Inhibition of the Transforming Growth Factor-β1/Smad Pathway.
TMT proteomics reveals that miR-425-5p promotes proliferation and metastasis of malignant melanoma by inhibiting SCARA5.
Functional characterization of CASP, a CUX1 isoform, reveals its tumor-promoting role in colorectal cancer via TRIM21-mediated signaling.
PARP-1 couples β-catenin/TCF4 signaling to epithelial-mesenchymal transition in endometriosis.
Mitochondrial uncoupling sensitizes gastric cancer cells to elesclomol-induced cuproptosis via FDX1/DLAT upregulation.
Melatonin promotes embryonic development by enhancing tryptophan metabolism and NAD + synthesis.
Gingerenone A ameliorates airway inflammation and remodeling in asthma by modulating the TLR4/MyD88/NF-κB pathway.
The circadian clock component PER2 deficiency aggravates airway epithelial remodeling through Wnt/β-catenin signaling pathway.
Identification of mitochondrial permeability transition-related gene signatures to predict lung adenocarcinoma survival and drug response.
Mitochondrial IRF3 drives pulmonary fibrosis by impairing mitophagy and triggering ferroptosis.
INHBB promotes liver metastasis of colorectal cancer via regulation of TGF-β/Smad signaling, EMT and anoikis resistance.
Angiotensin II type 1 receptor signaling promotes bladder cancer progression and its inhibition by Losartan.
Core fucosylation of NCEH1 by FUT8 promotes progression of high-grade serous ovarian cancer by driving tumor-associated macrophage M2 polarization.
Loss of TRAIP Could Attenuate the Breast Cancer Cells Development by Regulating PLSCR4 Stabilization.
CircRNA SLAIN1 is associated with reduced malignancy progression of glioblastoma and the M2-like polarization of tumor-associated macrophages via miR-1225-3p/NLRX1 axis.
FBXO32 activates the PI3K/AKT pathway by inhibiting PTEN through ubiquitination of TAL1 in hepatocellular carcinoma.
eIF3i facilitates NELFCD translation to promote metastasis via regulating EMT and invadopodia.
Bufalin Inhibits the PI3K/AKT Pathway by Targeting GTF3C4 to Impede Breast Cancer Progression.
SLC2A3-Mediated Lactate Metabolism Promotes Lung Cancer Bone Metastasis by Modulating P53 Lactylation and Immune Evasion.
Tumor-Associated Macrophage-Derived CXCL1 Promotes Endometrial Cancer Progression Through the CXCR2/NF-κB Pathway.
Novel transcription factor zinc finger 514 suppresses lung adenocarcinoma progression and enhances cisplatin sensitivity via transcriptional repression of COL1A1.
UCHL3 Promotes Triple-Negative Breast Cancer Metastatic Potential Through Enhancing Cell Migration and Invasion.
Zona pellucida is required for oocyte actin cortex and oocyte-somatic cell interactions during oocyte growth.
Supramolecular dynamic hydrogels loaded with bevacizumab nanoparticles promote hyaline cartilage regeneration by inhibiting angiogenesis.
Gallic acid: A promising anti-non-small cell lung cancer compound targeting early growth response protein-1 for apoptosis and ferroptosis.
Targeting keratin 6 A overcomes gemcitabine resistance by restoring equilibrative nucleoside transporter 1 and TAM-mediated metabolic compensation in pancreatic cancer.
KIAA1429 promotes clear cell renal cell carcinoma progression by regulating MYC mRNA stability.
IL-5 promotes airway remodeling in asthma by mediating epithelial-mesenchymal transition via the AKT/NLRP3 pathway.
TRIM29 suppresses malignant progression in lung squamous cell carcinoma by shaping an immunosuppressive tumor microenvironment.
SEMA6A overexpression inhibited tumor growth and metastasis in colorectal cancer.
LTF regulates glioblastoma progression and temozolomide resistance via the NF-κB signaling pathway.
ZMIZ2/MCM3 Axis Participates in Triple-Negative Breast Cancer Progression.
CEP55 Promotes Acral Melanoma Progression via MAPK Pathway and Predicts Survival Following Immunotherapy.
Terpinen-4-ol suppresses proliferation and motility of cutaneous squamous cell carcinoma cells by enhancing calpain-2 expression.
ARPC1B Promotes Clear Cell Renal Cell Carcinoma Progression via the Wnt/β-Catenin Signaling Pathway.
Hsa_piR_016975 Is a Novel Target of Nanotherapy that Boosts Hepatoma Progression and Sorafenib Resistance by Abating Maspin/GPX4-Mediated Ferroptosis.
Plinabulin exerts an anti-proliferative effect via the PI3K/AKT/mTOR signaling pathways in glioblastoma.
Smad7 ameliorate small airway remodeling in COPD by modulating epithelial-mesenchymal transition.
Cancer-associated Fibroblast-like Cells Promote Osteosarcoma Metastasis by Upregulation of Phosphoserine Aminotransferase 1 and Activation of the mTOR/S6K Pathway.
APOE suppresses osteosarcoma by modulating ferroptosis through the mTOR/Stat3 signaling pathway.
Smad2 Cooperating with TGIF2 Contributes to EMT and Cancer Stem Cells Properties in Pancreatic Cancer via Co-Targeting SOX2.
Identification of MAPK12 as a Prognostic Biomarker for Esophageal Carcinoma Using Bioinformatics and Machine Learning.
High SRD5A3 expression is correlated with promotion of proliferation and inhibition of apoptosis in B-cell non-Hodgkin lymphoma and suggests a poor prognosis.
Exploring the level of metabolic reprogramming and the role of prognostic factor SF3A3 in hepatocellular carcinoma through integrated single-cell landscape analysis.
Inhibition of HPSE/SDC-2 axis-induced epithelial-mesenchymal transition for treating IC/BPS.
IGF2BP2 contributes to thyroid cancer progression by enhancing the stability of m6A-modified CTSH mRNA.
Exosome-Delivered circFOXP1 Upregulates Autophagy and Promotes Hepatocellular Carcinoma Progression Through Its Encoded p196 Protein Targeting the KHDRBS3/ULK1 Axis.
Ginger-Derived Exosome-Like Nanoparticles Loaded With Indocyanine Green Enhances Phototherapy Efficacy for Breast Cancer.
Mechanistic Exploration of Shugan Jianpi Formula for Treating Triple-Negative Breast Cancer Under Chronic Stress: A Network Pharmacology-Guided Experimental Study.
Abnormally Activated MNX1 Promotes Tumor Growth and Osimertinib Resistance and Predicts Survival in EGFR-Mutant Lung Adenocarcinoma.
PTPRN promotes glioma cell proliferation, migration, and invasion by regulating the EMT pathway.
Finerenone Ameliorates High Glucose-Induced Podocytes Epithelial-Mesenchymal Transition Through the Regulation of Krüppel-Like Factor 5 in Diabetic Nephropathy.
Ginsenoside Rg3 exerts anticancer effects in lung cancer through metabolite Histon H3.
As a New Tumor Suppressor Gene, PID1 Activates the AMPK-mTOR Signal to Inhibit the Progression of Bladder Cancer.
A novel EMT-related risk score model for Uveal melanoma based on ZNF667-AS1 and AP005121.1.
COL6A2 drives clear cell renal cell carcinoma progression via integrin-dependent modulation of Wnt/β-catenin signaling.
Comprehensive Bioinformatics Analysis and Validation of the Mechanism of Glutamic-pyruvic Transaminase 2 in Bladder Cancer.
Hypoxia upregulate TPM4 expression to strengthen epithelial-mesenchymal transition that promotes lymph node metastasis of papillary thyroid cancer.
Cardamonin induces apoptosis of colorectal cancer cells via targeted inhibition of the JAK/STAT3/epithelial-mesenchymal transition (EMT) signaling axis.
Prognostic modeling of glioma using epilepsy-related genes highlights PAX3 as a regulator of migration and vorinostat sensitivity.
circWWC3 enhances the progression of triple-negative breast cancer by interacting with vimentin to regulate the secretion of CSF2.
Thymidine kinase 1 related to Prolif-like T cells promoted GBM through regulation of cell cycle and EMT signals: a comprehensive research based on multi-omics analysis and experimental validation.
Reciprocal activation between M1 macrophages and trophoblasts through CXCL9/STAT1/ZEB1/CCL2 axis promotes recurrent spontaneous abortion.
CPLX1 is a novel prognostic biomarker in CRC correlating with immunotherapy resistance and ferroptosis.
Dissecting the multi-omics landscape of TEAD1 in hepatocellular carcinoma: cycle regulation and metastatic potential.
The miR-941/FOXN4/TGF-β feedback loop induces N2 polarization of neutrophils and enhances tumor progression of lung adenocarcinoma.
Enhancing pancreatic cancer treatment: the role of H101 oncolytic virus in irreversible electroporation.
A comprehensive prognostic and immunological implications of Gremlin 1 in lung adenocarcinoma.
The regulatory role of the circELMOD3-associated ceRNA network in the progression and prognosis of hepatocellular carcinoma.
Cyperotundone promotes chemosensitivity of breast cancer via SRSF1.
Placental mesenchymal stem cell-derived interleukin-6 promotes neuroblastoma progression.
Targeting the self-amplifying loop between ATF6 and SNAI1 to inhibit epithelial‒mesenchymal transition in fibrotic lesions.
The ubiquitin ligase RCBTB2 regulates aggrephagy and inhibits prostate cancer progression by targeting GPAA1 for degradation.
HPV11 targeting PPARA regulates the autophagy to inhibit the occurrence and development of nasal inverted papilloma.
HMCN1 as a conserved biomarker of epithelial-mesenchymal transition: a cross-cancer analysis.
Targeting the N-cadherin/β-catenin axis with MSAB reverses malignant phenotypes in blast crisis of CML.
HOXB7 drives bladder cancer progression via H-Ras/ERK signaling: a potential therapeutic target and prognostic biomarker.
Securinine, a novel alkaloid, regulates cell cycle and EMT in gastric cancer by inducing iron-dependent cell death.
The anti-inflammatory effects of oridonin in resisting esophageal cancer.
Construction of a novel cuproptosis-related gene signature for predicting microenvironment, prognosis and therapeutic response in cervical cancer.
MiR-23b-3p ameliorates sepsis-induced acute lung injury by inhibiting SMAD3-mediated endothelial-mesenchymal transition.
L-cysteine mitigates busulfan-induced testicular injury through modulation of CBS/H(2)S axis.
Integrative pan-cancer analysis of UCP family and experimental validation identifies UCP2 as a potential therapeutic target for glioma.
GNA13 promotes brain metastasis of non-small cell lung cancer and EMT through the WNT/β catenin signaling pathway.
Construction of 3D Enhanced CT Radiomics-Based Model to Predict Circadian Gene Expression and Prognosis in Hepatocellular Carcinoma.
Ciprofol exerts anti-tumour effects in hepatocellular carcinoma through the Raf-MEK-ERK signalling pathway.
Mini and enhanced CRISPR activators for cancer therapies.
EIF3B‑METTL3 complex promotes cell proliferation, invasion and EGFR/AKT signaling in cervical cancer.
Up-regulation of NGEF via the BRAF(V600E) /ERK/AP1 pathway enhances invasion and migration abilities of BRAF(V600E)-mutant thyroid cancer.
p62/SQSTM1 impairs immunotherapy in lung adenocarcinoma by suppressing immune infiltration and peripheral immune response.
20-Acetylsinularolide B (ASB) From Lobophytum crassum Exhibits Anticancer Activity In Vitro Through IGF1R/PI3K/AKT/mTOR Pathway.
Ganoderic acid T, a novel activator of pyruvate carboxylase, exhibits potent anti-liver cancer activity.
Shenling Tongqiao powder targets TGF-β1/Smad-Wnt/β-catenin axis to suppress epithelial-mesenchymal transition in chronic rhinosinusitis.
The role of the aging process and related factor EMP1 in promoting progression of resectable pancreatic cancer.
Suppressed autophagy of thymic cells promotes apoptosis and thymic atrophy in COPD.
Integrator Complex Subunit 6 Regulates Biological Nature of Hepatocellular Carcinoma by Modulating Epithelial-Mesenchymal Transition.
A Novel Nuclear-Localized Micropeptide, MP60, Promotes Hepatocellular Carcinoma Progression via the Epithelial-Mesenchymal Transition.
LncRNA LOXL1-AS1 promotes ovarian cancer progression by enhanced BRIP1 mRNA stability.
NRF2 promotes the migration of ovarian cancer cell lines by targeting TAGLN mediated epithelial-mesenchymal transition.
Circular RNA hsa_circ_0006522 correlates with unfavorable prognosis and promotes the proliferative, migrative, and invasive abilities of breast cancer cells.
DTX3 inhibits cell migration, invasion, and epithelial-mesenchymal transition in colorectal cancer through the AKT signaling pathway.
C1orf116 inhibits acquired resistance to EGFR inhibitors in EGFR mutant lung adenocarcinoma by suppressing the ATM/ATR pathways.
CHD4 drives gastric cancer metastasis via MYH9/GSK3β/β-catenin axis and WNT/EMT pathway activation.
LCN2-positive alveolar type II cells promote silica-induced pulmonary fibrosis via STAT3-TGF-β1-Smad3-mediated signaling.
Overexpression of alcohol dehydrogenase 1 A inhibits the progress of triple negative breast cancer via Wnt/β-catenin signaling.
TAIII Suppresses the Growth of T790M-Mutant Non-Small-Cell Lung Cancer by Targeting the EGFR/ERK Signaling Pathway.
JMJD6-driven epigenetic activation of COL4A2 reprograms glioblastoma vascularization via integrin α1β1-dependent PI3K/MAPK signaling.
Fluzoparib disrupts Golgi apparatus to inhibit O-GlcNAcylation and nuclear translocation of β-catenin to attenuate ovarian cancer invasion and metastasis.
Orthosteric-allosteric dual inhibitors of PI5P4Kγ with potent antitumor activity in non-small cell lung cancer.
Biphasic Adaptations of Gastric Epithelial Cells in Chronic H. pylori Infection from Stress to Tolerance.
Rictor stability mediated by USP9X regulates embryo implantation by participating in lipid metabolism of endometrium†.
DLGAP5 facilitates glioblastoma growth and tumor-associated macrophage M2 polarization.
CENPA-driven transcriptional activation of ECT2 enhances EGFR inhibitor resistance in lung adenocarcinoma.
Loss of MBD2 is associated with tumor growth in small intestinal neuroendocrine tumors.
Single-cell multi-omic and spatial profiling of esophageal squamous cell carcinoma reveals the immunosuppressive role of GPR116(+) pericytes in cancer metastasis.
LGI3 promotes the progression of TFE3-rearranged renal cell carcinoma through GEMIN6/AURKB axis.
USP32 stabilizes SEMA4C to promote malignant behavior of colon cancer cells.
miR-29a-3p participates in the pathogenesis of spontaneous abortion by inhibiting trophoblast function targeting COL4A2/COL5A1.
Phosphodiesterase 12 facilitates the growth and metastatic capabilities of gastric cancer cells by activating the TCAF2/JAK2/STAT3 axis.
KIF18B drives the malignant progression of gliomas by activating the Notch pathway.
Glucose Deprivation-Induced Disulfidptosis via the SLC7A11-INF2 Axis: Pan-Cancer Prognostic Exploration and Therapeutic Validation.
Discovery of Natural Compound α-Hederin via Large-Scale Screening as a Targeted JAK/STAT3 Inhibitor for Ovarian Cancer Therapy.
Epigenetic potentiation of 5-fluorouracil by HDAC inhibitor quisinostat enhances antitumor effects in colorectal cancer.
Oncogenic Role of SAMD4B in Breast Cancer Progression by Activating Wnt/β-Catenin Pathway.
KAT2A-H3K79succ-Mediated SH2B3 Upregulation Promotes TNBC Metastasis Through Diminishing the Ubiquitin-Dependent Degradation of Vimentin.
miR-196a-5p promotes the proliferation, migration, and invasion of esophageal squamous cell carcinoma by targeting LIFR.
Tanshinone IIA inhibits heat-induced growth of p53-mutant Huh-7 hepatocellular carcinoma by modulating osmotic homeostasis and glycolysis through targeting ALDH7A1.
FUT8 promotes HDM-induced glycolysis, epithelial-mesenchymal transition and inflammation in bronchial epithelial cells by inducing N-glycosylation modification of GLUT1.
RPL22L1-Myc positive feedback loop drives lung adenocarcinoma progression.
α-hederin inhibits cervical cancer progression by inducing DNA damage-dependent cell cycle blockade and apoptosis.
Fusobacterium nucleatum increases CTGF expression through TLR2-YAP signaling axis in cancer-associated fibroblasts, thereby promoting colorectal cancer progression.
The deubiquitination enzyme USP14 promotes the tumourigenesis of gastric cancer by enhancing c-MYC nuclear translocation through deubiquitination of KPNA2.
A Cell-Potent Bisubstrate Inhibitor to Probe NatD Acetyltransferase Activity.
Cigarette smoke extract promotes metastasis and oxaliplatin resistance in colon adenocarcinoma through GDF15/ERBB2/AKT pathway.
TGFβ1-TNFα-regulated secretion of neutrophil chemokines is independent of epithelial-mesenchymal transition in breast tumor cells.
The oncogenic role of the circ_0003997/miR-370-3p/HMGA2 axis in papillary thyroid cancer.
LAMC1 aggravates diabetic retinopathy through PI3K/AKT signaling-regulated epithelial-mesenchymal transition in retinal pigment epithelial cells.
Harnessing TP73‑targeted nintedanib: A novel strategy to halt triple‑negative breast cancer via p53‑PPARα/PI3K‑Akt pathway suppression.
SP1-Mediated upregulation of CLEC18B promotes the proliferation and metastasis of glioma through regulation of the Wnt/β-Catenin/EMT Pathway.
The dual role of interleukin-22: balancing protection and risk in pregnancy during inflammatory challenges.
BUB1B promotes homologous recombination‑mediated DNA damage repair in breast cancer cells through the PI3K/AKT signaling pathway.
METTL16 promotes progression of clear cell renal cell carcinoma via up-regulating N6-methyladenosine modification of KLK4 mRNA.
Integrative multi-omics analysis and experimental validation reveal centromere protein W as a potential therapeutic target and predictive biomarker in renal clear cell carcinoma.
Galectin-9 promotes colon cancer development by polarizing macrophages toward the M2 phenotype.
UBE2O-mediated ubiquitylation directs cytoplasmic CTNNA1 to promote cell-to-ECM adhesions.
A Shikonin Derivative Induces Excessive Autophagy in Pancreatic Cancer Cells.
TRIB3 promotes endometrial cancer progression through interacting with E2F1 and enhancing PKM2-mediated tumor glycolysis.
N-glycosylation stabilized TNFAIP6 promotes ovarian cancer metastasis by activating the PI3K-AKT signaling pathway.
The E3 ubiquitin ligase TRIM31 enhances the progression of esophageal cancer through the ubiquitination of BBOX1.
RAB26 promotes prostate cancer progression via the MAPK/ERK-TWIST1 signaling axis.
RTA-408 Enhances Radiosensitivity and Inhibited Tumor Progression via JNK Pathway in Glioblastoma.
HCAR2 inhibits prostate cancer invasion and metastasis by regulating cAMP signaling pathway.
GLMP promotes EGFR-TKI resistance by activating autophagy and RhoA pathway in non-small cell lung cancer.
Protein kinase D2-mediated maintenance complex component 2 phosphorylation promotes bladder cancer progression.
Silencing Clusterin Could Attenuate the Cell Properties of HCV Core Protein-Expressing HCC Cell Line.
Dynamic remodelling of epithelial plasticity in colorectal cancer from single-cell and spatially resolved perspectives.
Keratin 80 serves as a potential biomarker in metastatic breast cancer.
Inhibition of FXa could be a novel therapeutic target associated with hypoxia-associated tumor behavior?
Loss of Calpain-2 attenuates TGF-β-driven Epithelial-Mesenchymal transition and invasive behavior in A549 lung cancer cells.
Ozone aging amplifies the tumor-promoting effects associated with low-dose graphene oxide exposure in bladder tumors via the integrin αV signaling pathway.
Antimony exposure induces bladder cancer metastasis via activation of the SUMOylation-dependent TGF-β/Smad2/3 axis.
Exosomal lncRNA MIR210HG derived from hypoxic TAMs promotes the metastasis of triple negative breast cancer.
MiR-5095 inhibits proliferation, migration, and invasion of gastric cancer cells by targeting CEACAM5.
A PCD-related prognostic signature and the oncogenic role of TRIM8 in osteosarcoma progression.
Overexpression of PLK1 Molecule Following Incomplete Thermal Ablation Promotes the Proliferation and Invasion of Residual Hepatocellular Carcinoma.
ARMC10 Drives Glioblastoma Progression Through Activating Notch Pathway.
KMT2A facilitates the epithelial-to-mesenchymal transition and the progression of ovarian cancer.
PRSS23-eIF4E-c-Myc axis promotes gastric tumorigenesis and progression.
Lipocalin 2 Facilitates the Initial Compromise of the Blood-Brain Barrier Integrity in Chronic Cerebral Hypoperfusion.
An exploration on the involvement of the methyltransferase like 3-m(6)A‑zinc finger MYM-type containing 1 axis in the progression of liver hepatocellular carcinoma.
HKDC1 promotes colorectal cancer progression by regulating RCOR1 expression to activate the Wnt/β-catenin pathway, enhancing proliferation, migration, and epithelial-mesenchymal transition.
Kv1.3 expression on CD4 (+) T cells promotes interleukin-17A-associated airway inflammation and airway remodeling in asthma.
PTPRG-AS1 regulates the KITLG/KIT pathway through the ceRNA axis to promote the malignant progression of gastric cancer and the intervention effect of Compound Kushen injection on it.
CHPF2 as a novel biomarker and ponicidin as a potential therapeutic agent in hepatocellular carcinoma.
Circular RNA ATP9A Stimulates Non-small Cell Lung Cancer Progression via MicroRNA-582-3p/Ribosomal Protein Large P0 Axis and Activating Phosphatidylinositol 3-Kinase/Protein Kinase B Signaling Pathway.
EFNA2 Mediates Stiffness-Regulated Hypopharyngeal Cancer Progression.
Metabolic-associated fatty liver disease (MAFLD) promotes the progression of hepatocellular carcinoma by enhancing KIF20A expression.
PCSK9 promotes progression of anaplastic thyroid cancer through E-cadherin endocytosis.
The high expression of Long noncoding RNA TEX41 promotes the proliferation, migration, and invasion of hepatocellular carcinoma.
The lncRNA MIR22HG suppresses prostate cancer cell proliferation, migration, and epithelial-mesenchymal transition via the miR-4428/PCDH9 axis.
Enhanced mitochondrial biogenesis facilitates the development of cutaneous squamous cell carcinoma.
DEC1 promotes breast cancer bone metastasis through transcriptional activation of CXCR4.
GP73-dependent regulation of exosome biogenesis promotes colorectal cancer liver metastasis.
Cinobufagin inhibits hepatocellular carcinoma EMT-like stemness via VEGF/VEGFR2 autocrine signaling.
The Therapeutic Potential of Bombyx Batryticatus for Chronic Atrophic Gastritis Precancerous Lesions via the PI3K/AKT/mTOR Pathway Based on Network Pharmacology of Blood-Entering Components.
MiR-493-5p functions as a tumour suppressor in head and neck squamous cell carcinoma progression by targeting HIF-1α.
Delivery of bone marrow mesenchymal stem cell-derived exosomes into fibroblasts attenuates intestinal fibrosis by weakening its transdifferentiation via the CCN2-TGF-β axis.
miRNA-1229-5p promotes migration and invasion and suppresses apoptosis of endometrial cells via the STMN1/p38 MAPK axis in endometriosis.
GALR1 and PENK serve as potential biomarkers in invasive non-functional pituitary neuroendocrine tumours.
TMBIM1 promotes epithelial mesenchymal transition by accelerating autophagic degradation of E-cadherin in glioblastoma.
Fibrogenesis-driven tumor progression in clear cell renal cell carcinoma: prognostic, therapeutic implications and the dual role of neuropilin-1.
Exploration of the pharmacological substance basis and efficacy evaluation of fufang she-she-cao (Hedyotis diffusa formula) in repressing gastric cancer.
Knowledge-guided multi-level network modeling with experimental characterization identifies PRKCA as a novel biomarker and tumor suppressor triggering ferroptosis in prostate cancer.
CKIP-1 inhibits M2 macrophage polarization to suppress the progression of gastric cancer by inactivating JAK/STAT3 signaling.
FAK and p130Cas Modulate Stiffness-Mediated Early Transcription and Cellular Metabolism.
Targeting ADAR1 with a small molecule for the treatment of prostate cancer.
Dihydroartemisinin Inhibits Epithelial-Mesenchymal Transition Progression in Medullary Thyroid Carcinoma Through the Hippo Signaling Pathway Regulated by Interleukin-6.
UBE2Q1 as a novel cancer biomarker for lung adenocarcinoma.
USP1 promotes pancreatic cancer progression and autophagy by deubiquitinating ATG14.
The MCM6-c-Myc positive feedback loop mediates bladder cancer progression and cisplatin resistance.
High MICAL-L2 promotes cancer progression and drug resistance in renal clear cell carcinoma cells through stabilization of ACTN4 following vimentin expression.
circTUBD1-hnRNPK Regulates the Proliferation and Migration of LSCC by Targeting CCAR1.
Melanoma Cell Adhesion Molecule Plays a Pivotal Role in Proliferation, Migration, Tumor Immune Microenvironment, and Immunotherapy in Colorectal Cancer.
circFOXK2 Stabilizes STMN1 mRNA via PABPC1 to Promote the Progression of NSCLC.
Procyanidin B2 alleviates damage to mouse testicular tissue after freezing by inhibiting oxidative stress and apoptosis.
Melatonin affects trophoblast epithelial-to-mesenchymal transition and oxidative damage resistance by modulating GDF15 expression to promote embryo implantation.
HNRNPC promotes progression of non-small cell lung cancer by maintaining TFAP2A mRNA stability.
Parvimonas micra promotes oral squamous cell carcinoma metastasis through TmpC-CKAP4 axis.
Single-cell and spatial transcriptome profiling reveal CTHRC1+ fibroblasts promote EMT through WNT5A signaling in colorectal cancer.
NEAT1 promotes the perineural invasion of pancreatic cancer via the E2F1/GDNF axis.
Cyanidin-3-glucoside upregulated NDRG2 through the PI3K/AKT pathway to alleviate EMT and ECM in renal fibrosis.
c-Jun promotes neuroblastoma cell differentiation by inhibiting APC formation via CDC16 and reduces neuroblastoma malignancy.
miR-378d suppresses gastric cancer metastasis by targeting METTL4 to inhibit epithelial-mesenchymal transition.
Protocol for generating brain metastatic tumor cells through repeated intracardiac injections in mice.
YWHAG promotes the progression of lung adenocarcinoma through the JAK2/STAT3 pathway.
Single-molecule m(6)A detection empowered by endogenous labeling unveils complexities across RNA isoforms.
Starvation-induced HBP metabolic reprogramming and STAM2 O-GlcNAcylation facilitate bladder cancer metastasis.
Oxidative Stress Regulates CDH3 Expression in Lung Cancer Cells via OGG1-Mediated SP1 Binding.
CENPF interaction with PLA2G4A promotes glioma growth by modulating mTORC1 and NF-κB pathways.
miR-135b-5p/PDE3B Axis Regulates Gemcitabine Resistance in Pancreatic Cancer Through Epithelial-Mesenchymal Transition.
Granzyme B Promotes Proliferation, Migration and EMT Process in Gastric Cancer.
H3K18 lactylation-mediated SIX1 upregulation contributes to silica-induced epithelial-mesenchymal transition in airway epithelial cells.
LncRNA MKLN1-AS promotes glioma tumorigenesis and growth via activating the Hippo pathway through miR-126-5p/TEAD1 axis.
GJB2 as a novel prognostic biomarker associated with immune infiltration and cuproptosis in ovarian cancer.
LncRNA SNHG14 Regulated by ZNF460 Promotes Gastric Cancer Progression and Metastasis by Targeting the miR-206/FNDC3A Axis.
Charge-reversed small extracellular vesicles from human adipose-derived mesenchymal stromal cells attenuate renal fibrosis postacute kidney injury by inhibiting epithelial-mesenchymal transition progression in SD rat model.
Rotenone adaptation promotes migration and invasion of p53-wild-type colon cancer through lipid metabolism.
MBD2 promotes epithelial-to-mesenchymal transition (EMT) and ARDS-related pulmonary fibrosis by modulating FZD2.
Distinct CTC Specific RNA Profile Enables NSCLC Early Detection and Dynamic Monitoring of Advanced NSCLC.
Oleanolic Acid Restores Drug Sensitivity in Sorafenib-resistant Hepatocellular Carcinoma: Evidence from In Vitro and In Vivo Studies.
Dexmedetomidine promotes colorectal cancer progression mediated by gamma-aminobutyric acid signaling.
IGFBP2 Modulates Trophoblast Function and Epithelial-Mesenchymal Transition in Preeclampsia via the PI3K/AKT Signaling Pathway.
Fibulin-4 is highly expressed in metastatic breast cancer and can serve as a target of peptide-based imaging probes and experimental therapeutics.
DDX5 super-enhancer promotes vasculogenic mimicry formation and metastasis in nasopharyngeal carcinoma by enhancing ADAM10 transcription.
Airway microbiota associated D-phenylalanine promotes non-small cell lung cancer metastasis through epithelial mesenchymal transition.
Nobiletin from Citrus reticulata Blanco alleviates pulmonary fibrosis through inhibiting the PI3K/AKT pathway and epithelial-mesenchymal transition.
Role of the USP7/FOXO3A axis in environmentally relevant doses of arsenic-induced lung carcinogenesis: Insights from bioinformatics analysis and model of human epithelial cell malignant transformation.
Curcumenol inhibits malignant progression and promotes ferroptosis via the SLC7A11/NF‑κB/TGF‑β pathway in triple‑negative breast cancer.
PUS7 promotes the progression of pancreatic cancer by interacting ANLN to activate MYC pathway.
TCF7 functions as a prognostic biomarker in bladder cancer by strengthening EMT and stemness associated with TGF-β/SMAD3 signaling.
CYP2A6 suppresses hepatocellular carcinoma via inhibiting SRC/Wnt/β-Catenin pathway.
HucMSC-Ex alleviates inflammatory bowel disease by regulating O-GlcNAcylation modification of RACK1 in intestinal epithelial cells.
Wenxia Changfu Formula inhibits NSCLC metastasis by halting TAMs-induced epithelial-mesenchymal transition via antagonisticallymodulating CCL18.
Identification of the Oncogenic Role of MSH2 in the Stemness and Progression of Glioma Through Regulating Wnt Signaling Pathway.
Neoadjuvant Chemotherapy With Cisplatin Up-Regulates GSDMD to Enhance Oral Squamous Cell Carcinoma Metastasis Through MMP14-Mediated EMT Activation.
M6A-Methylated circRAPGEF5 drives lung adenocarcinoma progression and metastasis via IGF2BP2/NUP160-mediated autophagy suppression.
P300-dependent acetylation of the FOXQ1 complex activates super-enhancers to promote colorectal cancer proliferation and metastasis.
RhoJ promotes the progression of clear cell renal cell carcinoma via the TNF-α/NF-κB axis.
Effects of PELP1 on proliferation, metastasis and angiogenesis of epithelial ovarian cancer.
GPX3 promotes cisplatin resistance in TNBC by manipulating ROS-TGFB1-ZEB2.
Terrestrosin D promotes autophagy and apoptosis of breast cancer cells through PSMD1-dependent activation of P53 pathway.
Curzerene suppresses epithelial-mesenchymal transition in gastric precancerous lesion cells through targeted regulation of YAP via the long non-coding RNA AFAP1-AS1.
Design, Synthesis, and Activity Evaluation of Novel Nucleosides as ADAR1 Inhibitor for the Treatment of Prostate Cancer.
DSS1 inhibits autophagy to activate epithelial-mesenchymal transition in a pro-metastatic niche of renal cell carcinoma.
Molecular function validation and prognostic value analysis of the cuproptosis-related gene ferredoxin 1 in papillary thyroid carcinoma.
P4HA2 promotes the progression of papillary thyroid cancer by enhancing degradation of IκBα to activate NF-κB signaling pathway.
Hypertension-related genes STOM, MEF2C promote proliferation and migration of clear cell renal cell carcinoma.
"TFEB-HNRNPA2B1": A positive feedback loop facilitating metastasis in hepatocellular carcinoma cells.
Secreted phosphoprotein 1 promotes the activation of keloid fibroblasts via the CD44/TGF-β1/Smad pathway.
Elevated SGO2 expression in lung adenocarcinoma promotes migration and invasion via MAD2 and correlates with poor prognosis.
FOXL2 Knockdown Inhibits the Progression of Endometriosis.
EIF4A3-Induced Circ_0059914 Promoted Angiogenesis and EMT of Glioma via the miR-1249/VEGFA Pathway.
EML4-ALK G1202R and EML4-ALK L1196M mutations induce crizotinib resistance in non-small cell lung cancer cells through activating epithelial-mesenchymal transition mediated by MDM2/MEK/ERK signal axis.
TMEM252 inhibits epithelial-mesenchymal transition and progression in papillary thyroid carcinoma by regulating Notch1 expression.
ATF1 regulates MAL2 expression through inhibition of miR-630 to mediate the EMT process that promotes cervical cancer cell development and metastasis.
4‑Methoxydalbergione inhibits the tumorigenesis and metastasis of lung cancer through promoting ferroptosis via the DNMT1/system Xc‑/GPX4 pathway.
NKD2 as a Mediator of IFIX Antioncogene-Induced Wnt Signalling and Epithelial-Mesenchymal Transition in Human OSCC.
NAP1L5 promotes epithelial-mesenchymal transition by regulating PEG10 expression in acute myeloid leukaemia.
Cyclovirobuxine D inhibits triple-negative breast cancer via YAP/TAZ suppression and activation of the FOXO3a/PINK1-Parkin pathway-induced mitophagy.
Mechanistic insights into the treatment of pulmonary fibrosis with bioactive components from traditional chinese medicine via matrix stiffness-mediated EMT.
Modified Zuojin pill alleviates gastric precancerous lesions by inhibiting glycolysis through the HIF-1α pathway.
TIFA enhances glycolysis through E2F1 and promotes the progression of glioma.
Hirudo extract ameliorates proliferative vitreoretinopathy by promoting autophagy and attenuating the THBS2/PI3K/Akt pathway.
Estrogen Receptor β Activation Mitigates Colitis-associated Intestinal Fibrosis via Inhibition of TGF-β/Smad and TLR4/MyD88/NF-κB Signaling Pathways.
MYBL2 promotes proliferation of clear cell renal cell carcinoma by regulating TOP2A and activating AKT/mTOR signaling pathway.
Pharmacological effects and mechanisms of danlong oral liquid in asthma airway remodeling: Insights from serum medicinal chemistry, network pharmacology, and experimental validation.
Formin protein DAAM1 positively regulates PD-L1 expression via mediating the JAK1/STAT1 axis in pancreatic cancer.
UBE2J1 is identified as a novel plasma cell-related gene involved in the prognosis of high-grade serous ovarian cancer.
DRAM1 enhances the proliferation and metastasis of gastric cancer through the PI3K/AKT/mTOR signaling pathway and energy metabolism.
Perilipin2-dependent lipid droplets accumulation promotes metastasis of oral squamous cell carcinoma via epithelial-mesenchymal transition.
Hypoxia and lipid metabolism related genes drive proliferation migration and immune infiltration mechanisms in colorectal cancer subtyping.
Hypoxia-induced circPLOD2a/b promotes the aggressiveness of glioblastoma by suppressing XIRP1 through binding to HuR.
MicroRNA-32-5p promotes the proliferation and metastasis of gastric cancer cells.
CircCCT2/miR-146a-5p/IRAK1 axis promotes the development of head and neck squamous cell carcinoma.
Heterogeneous nuclear ribonucleoprotein C promotes non-small cell lung cancer progression by enhancing XB130 mRNA stability and translation.
Molecule interacting with CasL-2 enhances tumor progression and alters radiosensitivity in cervical cancer.
Bisphenol S exposure promotes stemness of triple-negative breast cancer cells via regulating Gli1-mediated Sonic hedgehog pathway.
circ_0004662 contributes to colorectal cancer progression by interacting with hnRNPM.
NEK2 Promotes ESCC Malignant Progression by Inhibiting Cellular Senescence via the FOXM1/c-Myc/p27 Signaling Pathway.
Novel Diagnostic Biomarker BST2 Identified by Integrated Transcriptomics Promotes the Development of Endometriosis via the TNF-α/NF-κB Signaling Pathway.
β-Catenin mediated TAM phenotype promotes pancreatic cancer metastasis via the OSM/STAT3/LOXL2 axis.
Epigenetic silencing of JAM3 promotes laryngeal squamous cell carcinoma development by inhibiting the Hippo pathway.
Hypericin mediated photodynamic therapy induces ferroptosis via inhibiting the AKT/mTORC1/GPX4 axis in cholangiocarcinoma.
Ilicicolin C suppresses the progression of prostate cancer by inhibiting PI3K/AKT/mTOR pathway.
Ginsenoside Rb prevents the metastasis of hepatocarcinoma by blocking the platelet-tumor cell interaction.
EFNA4-enhanced deubiquitination of SLC7A11 inhibits ferroptosis in hepatocellular carcinoma.
FBXO2 as a switch guides a special fate of tumor clones evolving into a highly malignant transcriptional subtype in oral squamous cell carcinoma.
Negative air ions alleviate nicotine-induced renal damage of spontaneously hypertensive rats via inhibiting oxidative stress and TGF-β/Smad pathway.
Prenatal Perfluorooctanoic Acid (PFOA) exposure causes reproductive toxicity by disrupting the formation of transzonal projections (TZPs) and down-regulating Wnt4/β-catenin signaling pathway in progeny.
MATN1-AS1 Promotes Tumour Metastasis and Sunitinib Resistance via E2F2 in Clear Cell Renal Cell Carcinoma.
LAMP3-mediated epithelial-mesenchymal transition promotes the invasion and excessive proliferation of fibroblast-like synoviocytes in rheumatoid arthritis.
HECW1-Mediated Ubiquitination of HIPK2 Drives Metastasis in Gastric Cancer Through the AKT Signaling Pathway.
Mechanistic insights into PROS1 inhibition of bladder cancer progression and angiogenesis via the AKT/GSK3β/β-catenin pathway.
Endoplasmic reticulum stress-related CLIP4 plays a procarcinogenic role in hepatocellular carcinoma: an integrated analysis.
Synthesis of novel deuterated EGFR/ALK dual-target inhibitors and their activity against non-small cell lung cancer.
PTOV1 exerts pro-oncogenic role in colorectal cancer by modulating SQSTM1-mediated autophagic degradation of p53.
COMMD3 Regulates Copper Metabolism via the ATOX1-ATP7A-LOX Axis to Promote Multiple Myeloma Progression.
RPL22L1 fosters malignant features of cervical cancer via the modulation of DUSP6-ERK axis.
Aspirin impedes non-small cell lung cancer development via fine-tuning the CD36 localization regulated by GPIHBP1.
Discovery of Novel Aromatic Urea-Imidazole Salt Derivatives for Cancer Therapy via Targeting ERK1/2.
Molecular mechanism of Gancao Xiexin Decoction regulating EMT and suppressing hepatic metastasis of gastric cancer via the TGF-β1/SMAD pathway.
PTPRO represses breast cancer lung metastasis by inhibiting the JAK2-YAP axis.
Pingxiao pian attenuate invasiveness and proliferation of lung adenocarcinoma through regulating miR-29b-3p/TGF-β1/Smad/EMT pathway.
Phosphorylation of FOXN3 by NEK6 promotes pulmonary fibrosis through Smad signaling.
A novel piperine derivative HJJ_3_5 inhibits colorectal cancer progression by modulating EMT signaling pathways.
Constructing a highly sensitive duplex immunoassay using AuNPs and AgNPs as nanolabels for investigating the epithelial-mesenchymal transition occurring on circulating tumor cells with lung cancer patients.
Multi-omics analysis reveals the impact of YAP/TEAD4-mediated EIF5A1 expression on mitochondrial apoptosis and bladder cancer progression.
CircRNA circACTN4 Promotes the Progression of Epithelial-Mesenchymal Transition in Hepatocellular Carcinoma by Targeting the miR-424-5p/NCAPG/Wnt Axis.
B7-H3 enhances the malignant phenotype of colorectal cancer by activating the Wnt/β-catenin pathway mediated by CYP1B1.
IMUP promotes fatty acid metabolism and lung cancer progression by regulating TGF-β/SMAD3 signaling pathway.
TTK Defines a High-Risk Oral Squamous Cell Carcinoma Subtype Through Dual mTORC1/NF-κB Activation.
Taohong Siwu Decoction relieves renal fibrosis: based on network pharmacology and experimental confirmation.
Mechanistic insights into FUNDC2P4 and HSF1 regulation of EMT in residual hepatocellular carcinoma following insufficient radiofrequency ablation.
TLyp-1-modified exosome-mediated delivery of circRAPGEF5 ASO inhibits lung adenocarcinoma metastasis via regulating the miR-570-3p/SPP1 axis.
CircRAB23 functions as miR-532-3p sponge to promote the malignant proliferation and metastasis of intrahepatic cholangiocarcinoma through HMGA2-EMT axis.
Cholesterol metabolism in LUAD progression: GJB3 as a key target for cell‑based therapeutic interventions.
GLDC interacts with VPS34 to inhibit tumorigenesis and epithelial-mesenchymal transition in hepatocellular carcinoma.
Deoxycholic Acid and Lipoteichoic Acid cooperatively drive macrophage M2/M1 polarization via TGR5/STAT3 and TLR2/NF-κB to fuel HCC progression in obesity.
CircATP5C1 promotes triple-negative breast cancer progression by binding IGF2BP2 to modulate CSF-1 secretion.
The role and mechanisms of the microRNA-1180-3p/MKNK2/CREB3 signaling axis in tumor progression following insufficient radiofrequency ablation of colorectal cancer liver metastasis.
Juglone targets MMP-1 to inhibit gastric cancer progression.
Single-Cell and Spatial Transcriptomics-Based Research Reveals Association Between M2a Macrophages and Tumor Spread through Air Spaces in Lung Adenocarcinoma.
Acyl-CoA dehydrogenase long chain acts as a tumor-suppressive factor in lung adenocarcinoma progression.
Targeting the ST3 beta-galactoside alpha-2,3-sialyltransferase 1 (ST3Gal1) as a potential therapeutic strategy to overcome anti-VEGF resistance in endometrial cancer.
Desulfovibrio vulgaris flagellin exacerbates colorectal cancer through activating LRRC19/TRAF6/TAK1 pathway.
Design, synthesis, and evaluation of 5-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)-1H-indole-2-carboxamide derivatives as anti-HCC agents targeting Nur77.
Adipose-derived mesenchymal stem cell exosomes protect keratinocytes from high-glucose injury by modulating KEAP1/NRF2/HO-1 axis.
CircLRBA Promotes Epithelial-Mesenchymal Transition, Immune Evasion, Chemoimmunotherapy Resistance and Metastasis Through Stabilizing Twist1.
Skullcapflavone II Inhibits SLC1A4-Mediated L-Serine Uptake and Promotes Mitochondrial Damage in Gastric Cancer.
Obesity-induced gut microbiota transplantation promotes the occurrence and development of hepatocellular carcinoma.
METTL3-mediated m(6)A modification regulates OSCC progression via the HNRNPA2B1/FOXQ1 axis.
The SREBF2-ACOT7 axis promotes tumor progression and predicts prognosis in diffuse large b-cell lymphoma.
KY216-tubulin complex captures VASH2 to inhibit NSCLC metastasis.
Bile metabolite palmitic acid augments the migration of gallbladder cancer cells through the ROS/NF-кB signaling pathway.
Stem Cells From the Apical Papilla Cultured in Spheroids Spontaneously Differentiate Into Odontoblasts via N-Cadherin Downregulation.
EPI-SauriCas9-based mouse ovarian cancer models recapitulating pten deletion in patients.
EXOSC3 knockdown induces G1/S phase arrest to suppress hepatocellular carcinoma cell proliferation.
Shikonin inhibits multiple tumor malignant phenotypes and is associated with Hedgehog pathway downregulation in lung adenocarcinoma.
FOXL2 + cancer-associated fibroblasts enhances epithelial ovarian cancer development via TGFβ/Smad signaling.
[PSMD11 overexpression promotes epithelial-mesenchymal transition in gastric cancer and affects patient prognosis].
GPX8 is transcriptionally regulated by KLF16 and promotes osteosarcoma progression.
Porphyromonas gingivalis extracellular vesicles promotes tumor metastasis in esophageal squamous cell carcinoma by inducing PRKACB/JNK/ NFATC2 axis.
A novel super-enhancer-driven lncRNA LINC00973 governs head and neck squamous cell carcinoma progression through EN2.
Targeting the SMAD3/CISD2 axis suppresses bladder cancer progression by promoting ferroptosis in mesenchymal-like bladder cancer cells.
METTL3-mediated m6A modification of TACSTD2 mRNA inhibits papillary thyroid cancer progression by activating the TNF signaling and blocking epithelial-mesenchymal transition.
The role of hsa_circ_0000520 in breast cancer progression: insights into the miR-542-3p/TMBIM6 regulatory axis.
NAT10-mediated N4-acetylcytidine (ac4C) modification of PIK3R2 mRNA promotes malignant progression of glioblastoma.
Therapeutic targeting of interleukin-17C signaling in carcinogenesis of endometriosis.
S1PR3 Inhibition in alveolar epithelial cells alleviates pulmonary fibrosis by enhancing alveolar barrier function.
Haematococcus pluvialis ameliorates renal fibrosis by restoring mitophagy via PINK1-Parkin-p62-LC3 signaling.
CD36-mediated fatty acid metabolic reprogramming activates synovial fibroblasts and promotes rheumatoid arthritis progression.
CircRNA hsa_ circ_0009022 inhibits colorectal cancer progression by sponging miR-576-5p and complexing with FMRP.
The role of formin-like protein 1 in pancreatic cancer and its specific effects on immunity.
METTL1-mediated m7G modification promotes colorectal cancer metastasis via stabilization of ICAM-1.
P5CS deacetylation mediated by SIRT2 facilitates tumor growth by enhancing mitochondrial respiration in hepatocellular carcinoma.
Endoplasmic Reticulum Stress as a Regulator of High Glucose-Induced Epithelial-Mesenchymal Transition in Human Lens Epithelial Cells.
Mechanism of (-)-Englerin A and calcium binding on the human TRPC5 channel.
Application of PVA hydrogel loaded with luteolin nanoparticles in anti EMT treatment after GBM.
Thermosensitive hydrogel composite with si-Cx43 nanoparticles and anti-VEGF agent for synergistic treatment of diabetic retinopathy.
Homeobox C6 is Up-Regulated and Affects the Pathogenesis of Endometriosis.
circGAPVD1 inhibits the progression of gastric cancer through miR-4424/STK4 axis and encoding GAPVD1-137aa protein.
Dysregulated RNA m6A Methylation Contributes to the Metastasis of Gallbladder Cancer Through miR-146a-5p.
Single-cell transcriptomics and metabolomics reveal the potential role of ASRGL1 in metabolic reprogramming and invasion of nasopharyngeal carcinoma cells.
Revealing a new target: Celastrol alleviates pulmonary fibrosis by inhibiting PCAF.
Pyrrolidinium Fullerenes as YTHDF1 Inhibitors for Targeted Tumor Therapy.
F-box only protein 10 protects against kidney tubulointerstitial fibrosis by inhibiting ACSL4-mediated lipid peroxidation and ferroptosis.
HnRNPR promotes non-small cell lung cancer progression by protecting XB130 mRNA from XRN1- and DIS3L2-mediated degradation.
Circ847 upregulation via CAFs suppresses salivary adenoid cystic carcinoma progression through VIM-EMT.
GATA2 promotes cervical cancer progression under the transcriptional activation of TRIP4.
Nanoparticle conjugation of ginsenoside Rh2 enhanced antitumor efficacy on hepatocellular carcinoma.
Triptolide targets PPP2CA/ITGA5 axis to suppress lactate-driven ovarian cancer progression.
Promotion of the invasion and metastasis of breast cancer by B7-H3 through CCR5High tumor-associated macrophages.
Role of the transcription factor SOX8 in hepatocellular carcinoma development and lymph node metastasis.
Exploring the therapeutic effects and molecular mechanisms of total flavonoids of Abelmoschus manihot (L.) Medic in the treatment of IgA nephropathy based on WGCNA.
Exosomal Biglycan promotes gastric cancer progression via M2 polarization and CXCL10-mediated JAK/STAT1 activation.
ADAMTS2 mediates epithelial‒mesenchymal transition and inflammation in high-grade serous ovarian cancer: a study based on bioinformatic analyses and experiments.
Paris saponin VII restrains PD-L1 mediated immune evasion through the AKT1 and STAT3 signaling pathways.
Senescent fibroblasts secrete CTHRC1 to promote cancer stemness in hepatocellular carcinoma.
CircZFR/YTHDF3 axis drives lymph node metastasis in cervical cancer via FASN translation.
METTL3 promotes peritoneal metastasis of colorectal cancer through regulating m6A modification of NRXN3 mRNA.
HAS1(high) cancer associated fibroblasts located at the tumor invasion front zone promote oral squamous cell carcinoma invasion via ECM remodeling.
Suppressive effects of Momordica charantia MAP30 on the senescence, proliferation and migration of bladder cancer cells mediated by CENPA.
miRNA-204-5p acts as a tumor suppressor in gastric cancer by inhibiting cell migration, invasion, and glycolysis via the RAB22A/PI3K/AKT axis.
Isoliquiritigenin suppresses fatty acid synthesis and cancer cell migration in anaplastic thyroid carcinoma through AMPK/SREBF1 pathway.
PLEK2 promotes migration and invasion in pancreatic ductal adenocarcinoma by MMP1 through IL-17 pathway.
METTL3 and HERC4: Elevated Expression and Impact on Hepatocellular Carcinoma Progression.
Low molecular weight heparins promote migration and invasion of trophoblast cells through regulating the PI3K/AKT signaling pathway.
Cinobufacini Inhibits Survival and Metastasis of Hepatocellular Carcinoma via c-Met Signaling Pathway.
Self-assembled genistein nanoparticles suppress the epithelial-mesenchymal transition in glioblastoma by targeting MMP9.
FOXA2 Loss in TGF-β1-Induced EMT Suppresses Bisecting-GlcNAc N-Glycan Synthesis in Lung Adenocarcinoma.
Design, Synthesis, and Biological Evaluation of Naphthalimide-Polyamine Conjugate as a Potential Anti-Colorectal Cancer Agent.
Isoforskolin, adenylate cyclase agonist, inhibits endothelial-to-mesenchymal transition in atherosclerosis.
Cannabidiol Enhances the Anticancer Activity of Etoposide on Prostate Cancer Cells.
Escin Ia ameliorates DSS-induced chronic colitis in mice by inhibiting inflammation and oxidative stress via the LOXL2/MMP-9 pathway.
ELK4 induced upregulation of HOMER3 promotes the proliferation and metastasis in glioma via Wnt/β-catenin/EMT signaling pathway.
Development and Validation of a Prognostic Model for Lung Adenocarcinoma Based on CAF-Related Genes: Unveiling the Role of COX6A1 in Cancer Progression and CAF Infiltration.
Prepubertal Exposure to Tris(2-chloroethyl) Phosphate Disrupts Blood-Testis Barrier Integrity via Ferritinophagy-Mediated Ferroptosis.
Investigation of c-Fos/c-Jun Signaling Pathways in Periostracum Cicadae's Inhibition of EMT in Gastric Tissue.
Cancer-associated fibroblasts secrete CSF3 to promote TNBC progression via enhancing PGM2L1-dependent glycolysis reprogramming.
Natural Killer Cell Activation Signature Identifies Cyclin B1/CDK1 as a Druggable Target to Overcome Natural Killer Cell Dysfunction and Tumor Invasiveness in Melanoma.
The highly expressed GOLPH3 in colorectal cancer cells activates smoothened to drive glycolysis and promote cancer cell growth and radiotherapy resistance.
Inhaled exogenous thymosin beta 4 suppresses bleomycin-induced pulmonary fibrosis in mice via TGF-β1 signalling pathway.
KIF2C promotes oral squamous cell carcinoma progression via PLK1 upregulation: implications for biomarker development and therapeutic targeting.
HNF4α-Mediated LINC02560 Promotes Papillary Thyroid Carcinoma Progression by Targeting the miR-505-5p/PDE4C Axis.
Development of Novel PRMT7 Inhibitors for the Treatment of Prostate Cancer.
Mechanism of Astragalus Polysaccharide in Alleviating Bovine Mammary Fibrosis Through ROS/NLRP3 Inhibition and EMT Regulation.
THBS2-producing matrix CAFs promote colorectal cancer progression and link to poor prognosis via the CD47-MAPK axis.
CD147 regulates the Rap1 signaling pathway to promote proliferation, migration, and invasion, and inhibit apoptosis in colorectal cancer cells.
HPV11E6/E7 induces nasal epithelial hyperplasia through JAK2/STAT3 signaling pathway.
P4HA1 is highly expressed in gastric cancer and promotes proliferation and metastasis of gastric cancer cells.
STEAP4 facilitates growth, migration, and invasion of prostate carcinoma through upregulation of NOTCH4.
VRK1 promotes epithelial-mesenchymal transition in hepatocellular carcinoma mediated by SNAI1 via phosphorylating CHD1L.
The LysoPS/GPR174 axis drives metastatic progression in esophageal squamous cell carcinoma through cAMP-PKA-CREB signaling activation.
CDC25A inhibition sensitizes melanoma cells to doxorubicin and NK cell therapy.
Static magnetic field inhibits epithelial mesenchymal transition and metastasis of glioma.
Oroxylin A may promote cell apoptosis and inhibit epithelial-mesenchymal transition in endometrial cancer, associated with the ERβ/PI3K/AKT pathway.
Proliferator-Activated Receptor Alpha Inhibits Abnormal Extracellular Matrix Accumulation and Maintains Energy Metabolism in Late-Onset Fuchs Endothelial Corneal Dystrophy.
YTHDF3 drives tumor growth and metastasis by recruiting eIF4B to promote Notch2 translation in breast cancer.
Bisphenol A-induced cancer-associated adipocytes promotes breast carcinogenesis via CXCL12/AKT signaling.
A Hybrid Manganese Nanoparticle Simultaneously Eliminates Cancer Stem Cells and Activates STING Pathway to Potentiate Cancer Immunotherapy.
Endoglin promotes cell migration and invasion in endometriosis by regulating EMT.
Single-Cell Spatial-Temporal Analysis of ZNF451 in Mediating Drug Resistance and CD8(+) T Cell Dysfunction.
Long non-coding RNA HOTAIR promotes tumourigenesis by affecting proliferation, invasion, migration, and apoptosis of liver cancer cells.
IL13RA2 promotes progression of infantile haemangioma by activating glycolysis and the Wnt/β-catenin signaling pathway.
Pretreatment with Inflammatory Factors Altered the Secretome of Human Amniotic Epithelial Cells.
Matrix Metalloproteinase 11 Promotes Migration and Invasion of Colorectal Cancer by Elevating Slug Protein.
Knockdown of ribosomal protein L22-like 1 arrests the cell cycle and promotes apoptosis in colorectal cancer.
HSPD1 Supports Osteosarcoma Progression through Stabilizing ATP5A1 and thus Activation of AKT/mTOR Signaling.
KIF15 promotes human glioblastoma progression under the synergistic transactivation of REST and P300.
RUNX1-PDIA5 Axis Promotes Malignant Progression of Glioblastoma by Regulating CCAR1 Protein Expression.
Hypoxia-driven TNS4 fosters HNSCC tumorigenesis by stabilizing integrin α5β1 complex and triggering FAK-mediated Akt and TGFβ signaling pathways.
Interference with mitochondrial metabolism could serve as a potential therapeutic strategy for advanced prostate cancer.
The H2Valdien derivatives regulate the epithelial-mesenchymal transition of hepatoma carcinoma cells through the Hedgehog signaling pathway.
PTTG1 induces pancreatic cancer cell proliferation and promotes aerobic glycolysis by regulating c-myc.
miR-34b-5p suppresses the epithelial-mesenchymal transition and metastasis in endometrial cancer AN3CA cells by targeting ZEB1.
Pan-Cancer Screening and Validation of CALU's Role in EMT Regulation and Tumor Microenvironment in Triple-Negative Breast Cancer.
WTAP knockdown inhibits cell migration through regulating SNAIL1 expression in colorectal cancer.
Human umbilical cord mesenchymal stem cells derived-exosomes alleviate LPS-induced cervical inflammation and epithelial-mesenchymal transition.
NEDD1 overexpression increases cell proliferation, tumor immune escape, and drug resistance in LUAD.
KRT80 Promotes Lung Adenocarcinoma Progression and Serves as a Substrate for VCP.
Integrative Omics Analysis Reveals Metabolic Features of Ground-Glass Opacity-Associated Lung Cancer.
HULC-IGF2BP2 Interaction Drives Proliferation and Metastasis in Colorectal Cancer.
Capsaicin and Cold exposure promote EMT-mediated premetastatic niche formation to facilitate colorectal cancer metastasis.
IPCEF1: Expression Patterns, Clinical Correlates and New Target of Papillary Thyroid Carcinoma.
DOK1 facilitates the advancement of ccRCC.
DPP7 as a Potential Therapeutic Marker for Colorectal Cancer.
MPP7 mediates EMT via Wnt/β-catenin pathway to promote polarity changes in epithelial ovarian cancer cells.
Hypoxia-responsive gene F3 Promotes GBM Cell Proliferation and Migration through Activating NF-κB/p65 Signaling Pathway.
A Model to Predict Prognosis of Renal Cell Clear Cell Carcinoma Based on 3 Angiogenesis-related Long Non-coding RNAs.
CSF2 Impairs Nrf2 Signaling through the Akt/Mtor Pathway in the Development of Bladder Cancer.
Macranthoidin B restrains the epithelial-mesenchymal transition through COX-2/PGE(2) pathway in endometriosis.
The mechanism of PDE7B inhibiting the development of hepatocellular carcinoma through oxidative stress.
Development and verification of a manganese metabolism- and immune-related genes signature for prediction of prognosis and immune landscape in gastric cancer.
Identifying and assessing a prognostic model based on disulfidptosis-related genes: implications for immune microenvironment and tumor biology in lung adenocarcinoma.
TGIF2 is a potential biomarker for diagnosis and prognosis of glioma.
Extracellular putrescine can augment the epithelial-mesenchymal transition of gastric cancer cells by promoting MAL2 expression by elevating H3K27ac in its promoter region.
FSH induces EMT in ovarian cancer via ALKBH5-regulated Snail m6A demethylation.
POLR2J expression promotes glioblastoma malignancy by regulating oxidative stress and the STAT3 signaling pathway.
SSH3 promotes pancreatic cancer proliferation and migration by activating the notch signaling pathway.
High glucose-induced NCAPD2 upregulation promotes malignant phenotypes and regulates EMT via the Wnt/β-catenin signaling pathway in HCC.
FLNB overexpression promotes tumor progression and associates with immune suppression, evasion and stemness in pancreatic cancer.
Identification of hub genes within the CCL18 signaling pathway in hepatocellular carcinoma through bioinformatics analysis.
Early short-term hypoxia promotes epidermal cell migration by activating the CCL2-ERK1/2 pathway and epithelial-mesenchymal transition during wound healing.
The long noncoding RNA MIR4435-2HG enhances the migration, promotion, and glycolysis of nonsmall cell lung cancer cells by targeting the miR-371a-5p/SOX2/PI3K/Akt axis.
PCSK9 inhibitor alleviates experimental pulmonary fibrosis-induced pulmonary hypertension via attenuating epithelial-mesenchymal transition by suppressing Wnt/β-catenin signaling in vivo and in vitro.
Circ_0007386 Promotes the Progression of Hepatocellular Carcinoma Through the miR-507/ CCNT2 Axis.
The prognostic value and its relationship with immune infiltration of ACLY in clear cell renal cell carcinoma.
ACAT1 suppresses clear cell renal cell carcinoma progression by AMPK mediated fatty acid metabolism.
ETV4 promotes the progression of cholangiocarcinoma by regulating glycolysis via the TGF-β signaling.
N6-methyladenosine triggers renal fibrosis via enhancing translation and stability of ZEB2 mRNA.
Histone demethylase PHF8 promotes prostate cancer metastasis via the E2F1-SNAI1 axis.
Daphnetin induces ferroptosis in ovarian cancer by inhibiting NAD(P)H:Quinone oxidoreductase 1 (NQO1).
PRM1201 effectively inhibits colorectal cancer metastasis via shaping gut microbiota and short- chain fatty acids.
The 8-oxoguanine DNA glycosylase-synaptotagmin 7 pathway increases extracellular vesicle release and promotes tumour metastasis during oxidative stress.
BUB1 induces AKT/mTOR pathway activity to promote EMT induction in human small cell lung cancer.
CXCL16 promotes proliferation of head and neck squamous cell carcinoma by regulating GPX1-mediated antioxidant levels.
CRABP2 promotes cell migration and invasion by activating PI3K/AKT and MAPK signalling pathways via upregulating LAMB3 in prostate cancer.
Clarithromycin attenuates airway epithelial-mesenchymal transition in ovalbumin-induced asthmatic mice through modulation of Kv1.3 channels and PI3K/Akt signaling.
Activin A plays an essential role in migration and proliferation of hepatic stellate cells via Smad3 and calcium signaling.
TGF-β-induced lncRNA TBUR1 promotes EMT and metastasis in lung adenocarcinoma via hnRNPC-mediated GRB2 mRNA stabilization.
Anlotinib reverses osimertinib resistance by inhibiting epithelial-to-mesenchymal transition and angiogenesis in non-small cell lung cancer.
CircSEC24B activates autophagy and induces chemoresistance of colorectal cancer via OTUB1-mediated deubiquitination of SRPX2.
Methanolic Extract of Cimicifuga foetida Induces G(1) Cell Cycle Arrest and Apoptosis and Inhibits Metastasis of Glioma Cells.
Mesenchymal stem cells in tumor microenvironment: drivers of bladder cancer progression through mitochondrial dynamics and energy production.
Mediation of FOXA2/IL-6/IL-6R/STAT3 signaling pathway mediates benzo[a]pyrene-induced airway epithelial mesenchymal transformation in asthma.
A novel biomarker GATM suppresses proliferation and malignancy of cholangiocarcinoma cells by modulating the JNK/c-Jun signalling pathways.
LncRNA HIF1A-AS2 promotes triple-negative breast cancer progression and paclitaxel resistance via MRPS23 protein.
Design, Synthesis, and Biological Evaluation of Potent EZH2/LSD1 Dual Inhibitors for Prostate Cancer.
Promotion of apoptosis in melanoma cells by taxifolin through the PI3K/AKT signaling pathway: Screening of natural products using WGCNA and CMAP platforms.
Anti-cancer effects of nitazoxanide in epithelial ovarian cancer in-vitro and in-vivo.
The activation of adenosine monophosphate-activated protein kinase inhibits the migration of tongue squamous cell carcinoma cells by targeting Claudin-1 via epithelial-mesenchymal transition.
MIA3 promotes the degradation of GSH (glutathione) by binding to CHAC1, thereby promoting the progression of hepatocellular carcinoma.
Matrine inhibits invasion and migration of gallbladder cancer via regulating the PI3K/AKT signaling pathway.
IGFBP7 regulates cell proliferation and migration through JAK/STAT pathway in gastric cancer and is regulated by DNA and RNA methylation.
Wnt-5a-Receptor Tyrosine Kinase-Like Orphan Receptor 2 Signaling Provokes Metastatic Colonization and Angiogenesis in Renal Cell Carcinoma, and Prunetin Supresses the Axis Activation.
The effects of BMP2 and the mechanisms involved in the invasion and angiogenesis of IDH1 mutant glioma cells.
The expression and role of SUZ12 in lung adenocarcinoma.
Hypoxia-induced DTL promotes the proliferation, metastasis, and sorafenib resistance of hepatocellular carcinoma through ubiquitin-mediated degradation of SLTM and subsequent Notch pathway activation.
Coke oven emissions exacerbate allergic asthma by promoting ferroptosis in airway epithelial cells.
ATF4/NUPR1 axis promotes cancer cell survival and mediates immunosuppression in clear cell renal cell carcinoma.
LncRNA FEZF1-AS1 promotes pulmonary fibrosis via up-regulating EZH2 and targeting miR-200c-3p to regulate the ZEB1 pathway.
The prognostic significance of twist in pancreatic cancer and its role in cancer promotion through the regulation of the immune microenvironment and EMT mechanisms.
Dibenzolium induces apoptosis and inhibits epithelial-mesenchymal transition (EMT) in bladder cancer cell lines.
RHOF promotes Snail1 lactylation by enhancing PKM2-mediated glycolysis to induce pancreatic cancer cell endothelial-mesenchymal transition.
Erianin inhibits the progression of pancreatic cancer by directly targeting AKT and ASK1.
CircGNAO1 suppresses hepatocellular carcinoma progression and metastasis via sponging miR-182-5p and regulating FOXO1 expression.
Construction of an autophagy-related genes risk model as predicting prognosis: BAG1 suppresses growth of clear cell renal cell carcinoma.
SASS6 promotes tumor proliferation and is associated with TP53 and immune infiltration in lung adenocarcinoma.
MYO6 contributes to tumor progression and enzalutamide resistance in castration-resistant prostate cancer by activating the focal adhesion signaling pathway.
Ubiquitin Ligase TRIM22 Inhibits Ovarian Cancer Malignancy via TCF4 Degradation.
Integrative Omics Uncovers Low Tumorous Magnesium Content as A Driver Factor of Colorectal Cancer.
TGFβ1-TNFα regulated secretion of neutrophil chemokines is independent of epithelial-mesenchymal transitions in breast tumor cells.
SMEK1 promotes clear cell renal cell carcinoma progression via EGFR tyrosine-kinase dependent pathway.
Regulation of cervical cancer via G15-mediated inhibition of G protein-coupled estrogen receptor.
NOD2 reduces the chemoresistance of melanoma by inhibiting the TYMS/PLK1 signaling axis.
Circ_0084615 promotes epithelial-mesenchymal transition-mediated tumor progression in hepatocellular carcinoma.
Liquiritigenin inhibits the migration, invasion, and EMT of prostate cancer through activating ER stress.
N6-methyladenosine reader YTHDF3-mediated zinc finger protein 41 inhibits hepatocellular carcinoma progression by transcriptional repression of Snail.
PM(10) dysregulates epithelial barrier function in human corneal epithelial cells that is restored by antioxidant SKQ1.
NEU4-mediated desialylation enhances the activation of the oncogenic receptors for the dissemination of ovarian carcinoma.
Data-mining-based biomarker evaluation and experimental validation of SHTN1 for bladder cancer.
Long non-coding RNA AC010457.1 promotes the growth and EMT of gastric cancer via the PI3K/AKT axis.
Novel curcumin derivatives N17 exert anti-cancer effects through the CSNK1G3/AKT axis in triple-negative breast cancer.
Dysregulated lncSNHG12 suppresses the invasion and migration of trophoblasts by regulating Dio2/Snail axis to involve in recurrent spontaneous abortion.
Temperature-Sensitive Polymer-Driven Nanomotors for Enhanced Tumor Penetration and Photothermal Therapy.
Disruption of blood-brain barrier and endothelial-to-mesenchymal transition are attenuated by Astragalus polysaccharides mediated through upregulation of ETS1 expression in experimental autoimmune encephalomyelitis.
Cancer-Associated Endocrine Cells Participate in Pancreatic Carcinogenesis.
Quiescent cancer cells induced by high-density cultivation reveals cholesterol-mediated survival and lung metastatic traits.
Overexpression of microRNA-611 inhibits TGF-β-induced epithelial-mesenchymal transition and migration in lung cancer cells through MAPKAP1.
PLOD1 promote proliferation and migration with glycolysis via the Wnt/β-catenin pathway in THCA.
Repurposed genipin targeting UCP2 exhibits antitumor activity through inducing ferroptosis in glioblastoma.
NSUN2 Promotes Head and Neck Squamous Cell Carcinoma Progression by Targeting EMT-Related Gene LAMC2 in an m(5)C-YBX1-Dependent Manner.
HOXC12 promotes the invasion and migration of gastric cancer cells by upregulating SALL4 and activating Wnt/β-catenin signaling pathway.
CLIP170 enhancing FOSL1 expression via attenuating ubiquitin-mediated degradation of β-catenin drives renal cell carcinoma progression.
Epithelial differentiation of gingival mesenchymal stem cells enhances re-epithelialization for full-thickness cutaneous wound healing.
Tumor Protein D53 (TPD53): Involvement in Malignant Transformation of Low-Malignant Oral Squamous Cell Carcinoma Cells.
Intravenous injection of BMSCs modulate tsRNA expression and ameliorate lung remodeling in COPD mice.
The role of disulfidptosis-associated LncRNA-LINC01137 in Osteosarcoma Biology and its regulatory effects on macrophage polarization.
Methionine deprivation inhibits glioma proliferation and EMT via the TP53TG1/miR-96-5p/STK17B ceRNA pathway.
Arginine methylation-dependent TRIM47 stability mediated by CARM1 promotes the metastasis of hepatocellular carcinoma.
Loss of DNA Polymerase β Delays Atherosclerosis in ApoE(-/-) Mice Due to Inhibition of Vascular Smooth Muscle Cell Migration.
Effect and underlying mechanism of a photochemotherapy dual-function nanodrug delivery system for head and neck squamous cell carcinoma.
Dapagliflozin suppressed gastric cancer growth via regulating OTUD5 mediated YAP1 deubiquitination.
FXR deficiency induced ferroptosis via modulation of the CBP-dependent p53 acetylation to suppress breast cancer growth and metastasis.
Prohibitin 2 confers NADPH oxidase 1-mediated cytosolic oxidative signaling to promote gastric cancer progression by ERK activation.
APLN promotes the proliferation, migration, and glycolysis of cervical cancer through the PI3K/AKT/mTOR pathway.
TRAIP suppressed apoptosis and cell cycle to promote prostate cancer proliferation via TRAF2-PI3K-AKT pathway activation.
Synergistic anticancer effects of ginsenoside CK and gefitinib against gefitinib-resistant NSCLC by regulating the balance of angiogenic factors through HIF-1α/VEGF.
microRNA-141-3p Suppressed the Progression of the Clear Cell Renal Cell Carcinoma by Targeting Transforming Growth Factor Beta 2 Gene Expression.
The Jagged-1/Notch1 Signaling Pathway Promotes the Construction of Tissue-Engineered Heart Valves.
Daurisoline suppress glioma progression by inhibiting autophagy through PI3K/AKT/mTOR pathway and increases TMZ sensitivity.
Targeting miR-31 represses tumourigenesis and dedifferentiation of BRAF(V600E)-associated thyroid carcinoma.
SOAT1 regulates cholesterol metabolism to induce EMT in hepatocellular carcinoma.
The prognostic significance and potential mechanism of DBF4 zinc finger in hepatocellular carcinoma.
Modified Lichong decoction intervenes in colorectal cancer by modulating the intestinal flora and the Wnt/β-catenin signaling pathway.
Osteocytes support bone metastasis of melanoma cells by CXCL5.
miR-1202 regulates BPH-1 cell proliferation, apoptosis, and epithelial-to-mesenchymal transition through targeting HMGCL.
Exosomal circPOLQ promotes macrophage M2 polarization via activating IL-10/STAT3 axis in a colorectal cancer model.
Methylation-regulated tumor suppressor gene PDE7B promotes HCC invasion and metastasis through the PI3K/AKT signaling pathway.
Targeting the HSP47-collagen axis inhibits brain metastasis by reversing M2 microglial polarization and restoring anti-tumor immunity.
The role of USP7-YY1 interaction in promoting colorectal cancer growth and metastasis.
IL-1β promotes esophageal squamous cell carcinoma growth and metastasis through FOXO3A by activating the PI3K/AKT pathway.
E3 ubiquitin ligase UBR5 promotes gemcitabine resistance in pancreatic cancer by inducing O-GlcNAcylation-mediated EMT via destabilization of OGA.
MAP7 drives EMT and cisplatin resistance in ovarian cancer via wnt/β-catenin signaling.
lncRNA CERS6-AS1 upregulates the expression of ANLN by sponging miR-424-5p to promote the progression and drug resistance of lung adenocarcinoma.
PSMD12 promotes non-small cell lung cancer progression through activating the Nrf2/TrxR1 pathway.
CD74-ROS1 L2026M mutant enhances autophagy through the MEK/ERK pathway to promote invasion, metastasis and crizotinib resistance in non-small cell lung cancer cells.
RSK4 promotes the macrophage recruitment and M2 polarization in esophageal squamous cell carcinoma.
Subtle structural alteration in indisulam switches the molecular mechanisms for the inhibitory effect on the migration of gastric cancer cells.
MBIP promotes ESCC metastasis by activating MAPK pathway.
Multi-omics cluster defines the subtypes of CRC with distinct prognosis and tumor microenvironment.
ESCRT-I protein UBAP1 controls ventricular expansion and cortical neurogenesis via modulating adherens junctions of radial glial cells.
PELI1: key players in the oncogenic characteristics of pancreatic Cancer.
TROP2 is highly expressed in triple-negative breast cancer CTCs and is a potential marker for epithelial mesenchymal CTCs.
IGF2BP3 prevent HMGB1 mRNA decay in bladder cancer and development.
PDE12 disrupts mitochondrial oxidative phosphorylation and mediates mitochondrial dysfunction to induce oral mucosal epithelial barrier damage in oral submucous fibrosis.
HDAC3 promotes Sertoli cell maturation and maintains the blood-testis barrier dynamics.
Hypoxia-induced miR-5100 promotes exosome-mediated activation of cancer-associated fibroblasts and metastasis of head and neck squamous cell carcinoma.
The circRNA hsa-circ-0013561 regulates head and neck squamous cell carcinoma development via the miR-7-5p/PDK3 axis.
OTUD4 promotes the progression of glioblastoma by deubiquitinating CDK1 and activating MAPK signaling pathway.
Downregulation of HIGD1B induces mitochondria-mediated apoptosis in gastric cancer cells by inactivating Akt and ERK pathways.
ID2 promotes tumor progression and metastasis in thyroid cancer.
Increased FGL1 Expression Predicts Poor Prognosis and Promotes EMT in Head and Neck Squamous Cell Carcinoma.
Tweety homolog 3 promotes colorectal cancer progression through mutual regulation of histone deacetylase 7.
SLC11A1 promotes kidney renal clear cell carcinoma (KIRC) progression by remodeling the tumor microenvironment.
Exploring the regulatory role of FBXL19-AS1 in triple-negative breast cancer through the miR-378a-3p/OTUB2 axis.
Amentoflavone reverses epithelial-mesenchymal transition in hepatocellular carcinoma cells by targeting p53 signalling pathway axis.
Lysophosphatidic acid promotes ESCC progression by increasing the level of CCL2 secreted by esophageal epithelial cells.
Hypoxia differently regulates the proportion of ALDH(hi) cells in lung squamous carcinoma H520 and adenocarcinoma A549 cells via the Wnt/β-catenin pathway.
Glucose regulates the HMGB1 signaling pathway through SIRT1 in glioma.
Peptide Transporter 1-Mediated Dipeptide Transport Promotes Hepatocellular Carcinoma Metastasis by Activating MAP4K4/G3BP2 Signaling Axis.
OLFM4 promotes the progression of intestinal metaplasia through activation of the MYH9/GSK3β/β-catenin pathway.
POLR1D silencing suppresses lung cancer cells proliferation and migration via inhibition of PI3K-Akt pathway.
The Glabridin from Huangqin Decoction Prevents the Development of Ulcerative Colitis into Colitis-Associated Colorectal Cancer by Modulating MMP1/MMP3 Activity.
PSME3 promotes lung adenocarcinoma development by regulating the TGF-β/SMAD signaling pathway.
Analysis of cell death-related genes to evaluate the prognostic and immunotherapeutic value in bladder cancer.
N-cadherin dynamically regulates pediatric glioma cell migration in complex environments.
IFI16 promotes the progression of clear cell renal cell carcinoma through the IL6/PI3K/AKT axis.
ISG15 promotes tumor progression via IL6/JAK2/STAT3 signaling pathway in ccRCC.
The Therapeutic Role of NPS-1034 in Pancreatic Ductal Adenocarcinoma as Monotherapy and in Combination with Chemotherapy.
Repurposing homoharringtonine for thyroid cancer treatment through TIMP1/FAK/PI3K/AKT signaling pathway.
Association of mitochondrial phosphoenolpyruvate carboxykinase with prognosis and immune regulation in hepatocellular carcinoma.
An Antibody of the Secreted Isoform of Disintegrin and Metalloprotease 9 (sADAM9) Inhibits Epithelial-Mesenchymal Transition and Migration of Prostate Cancer Cell Lines.
SIAH2 is specifically expressed during cervical carcinogenesis, and closely relates to the abnormal proliferation of cervical epithelial cells.
IRTKS contributes to the malignant progression of cervical cancer cells.
DUSP5 regulated by YTHDF1-mediated m6A modification promotes epithelial-mesenchymal transition and EGFR-TKI resistance via the TGF-β/Smad signaling pathway in lung adenocarcinoma.
FLNA overexpression promotes papillary thyroid cancer aggression via the FAK/AKT signaling pathway.
Loss of PTPRS elicits potent metastatic capability and resistance to temozolomide in glioblastoma.
Parkin deficiency promotes liver cancer metastasis by TMEFF1 transcription activation via TGF-β/Smad2/3 pathway.
LncRNA AC100826.1 regulated PLCB1 to promote progression in non-small cell lung cancer.
LINC00460 promotes neuroblastoma tumorigenesis and cisplatin resistance by targeting miR-149-5p/DLL1 axis and activating Notch pathway in vitro and in vivo.
Baohuoside I chemosensitises breast cancer to paclitaxel by suppressing extracellular vesicle/CXCL1 signal released from apoptotic cells.
Targeting the PI3K/AKT/mTOR pathway offer a promising therapeutic strategy for cholangiocarcinoma patients with high doublecortin-like kinase 1 expression.
Deciphering glutamine metabolism patterns for malignancy and tumor microenvironment in clear cell renal cell carcinoma.
Immunohistochemistry identifies E-cadherin, N-cadherin and focal adhesion kinase (FAK) as predictors of stage I non-small cell lung carcinoma spread through the air spaces (STAS), and the combinations as prognostic factors.
CCL2 promotes EGFR-TKIs resistance in non-small cell lung cancer via the AKT-EMT pathway.
Construction of the pulmonary bio-adhesive delivery system of nintedanib nanocrystalline for effective treatment of pulmonary fibrosis.
Single-Cell and Spatial Transcriptome Profiling Identifies the Transcription Factor BHLHE40 as a Driver of EMT in Metastatic Colorectal Cancer.
Alpha 1,3 N-Acetylgalactosaminyl Transferase (GTA) Impairs Invasion Potential of Trophoblast Cells in Preeclampsia.
Fasudil attenuates oxidative stress-induced partial epithelial-mesenchymal transition of tubular epithelial cells in hyperuricemic nephropathy via activating Nrf2.
DNA demethylase TET2-mediated reduction of HADHB expression contributes to cadmium-induced malignant progression of colorectal cancer.
LINC01133 promotes pancreatic ductal adenocarcinoma epithelial-mesenchymal transition mediated by SPP1 through binding to Arp3.
CHMP3 promotes the progression of hepatocellular carcinoma by inhibiting caspase‑1‑dependent pyroptosis.
PKMYT1 induced by YAP/TEAD1 gives rise to the progression and worse prognosis of bladder cancer.
MicroRNA-10a-5p-mediated downregulation of GATA6 inhibits tumor progression in ovarian cancer.
Nucleoporin 93, a new substrate of the E3 ubiquitin protein ligase HECTD1, promotes esophageal squamous cell carcinoma progression.
Hematoporphyrin derivative photodynamic therapy induces apoptosis and suppresses the migration of human esophageal squamous cell carcinoma cells by regulating the PI3K/AKT/mTOR signaling pathway.
17β-Estradiol mediates TGFBR3/Smad2/3 signaling to attenuate the fibrosis of TGF-β1-induced bovine endometrial epithelial cells via GPER.
The homologous tumor-derived-exosomes loaded with miR-1270 selectively enhanced the suppression effect for colorectal cancer cells.
Hsa_circ_0013561 promotes progression of nasopharyngeal carcinoma by activating JAK2/STAT3 signaling pathway.
Plasma CircCYP24A1 as a Novel Biomarker of Esophageal Squamous Cell Carcinoma.
TMCO1 regulates cell proliferation, metastasis and EMT signaling through CALR, promoting ovarian cancer progression and cisplatin resistance.
Lactate accumulation induced by Akt2-PDK1 signaling promotes pulmonary fibrosis.
CTSC promoted the migration and invasion of glioma cells via activation of STAT3/SERPINA3 axis.
Transcription factor FOXP4 inversely governs tumor suppressor genes and contributes to thyroid cancer progression.
The Analysis of Embryoid Body Formation and Its Role in Retinal Organoid Development.
FBXO28 promotes cell proliferation, migration and invasion via upregulation of the TGF-beta1/SMAD2/3 signaling pathway in ovarian cancer.
Circular RNA DNAH14 molecular mechanism in an experimental model of hepatocellular carcinoma treated with Cobalt chloride to mimic the hypoxia-like response of transcatheter arterial chemoembolization.
The dopamine receptor D1 inhibitor, SKF83566, suppresses GBM stemness and invasion through the DRD1-c-Myc-UHRF1 interactions.
ERH gene knockdown inhibits the proliferation and migration of ARPE-19 cells through MCM complex and EMT process.
DDX60 Promotes Migration and Invasion of Head and Neck Squamous Cell Carcinoma Cell through the NF-κB/IFI27 Signaling Pathway.
A transcriptome based molecular classification scheme for cholangiocarcinoma and subtype-derived prognostic biomarker.
N-cadherin dynamically regulates pediatric glioma cell migration in complex environments.
Panax notoginseng saponin alleviates pulmonary fibrosis in rats by modulating the renin-angiotensin system.
Hydrogen sulfide attenuates atherosclerosis induced by low shear stress by sulfhydrylating endothelium NFIL3 to restrain MEST mediated endothelial mesenchymal transformation.
Cold atmospheric plasma sensitizes head and neck cancer to chemotherapy and immune checkpoint blockade therapy.
NMI promotes tumor progression and gemcitabine resistance in pancreatic cancer via STAT3-IFIT3 axis.
Spindle and kinetochore-related complex subunit 3 has a protumour function in osteosarcoma by activating the Notch pathway.
Serabelisib regulates GSDMD-mediated pyroptosis, apoptosis and migration of hepatoma cells via the PI3K/Akt/E-cadherin signaling pathway.
Comprehensive analysis of PSMD family members and validation of PSMD9 as a potential therapeutic target in human glioblastoma.
Promoting effect and immunologic role of secretogranin II on bladder cancer progression via regulating MAPK and NF-κB pathways.
Exosome-delivered miR-410-3p reverses epithelial-mesenchymal transition, migration and invasion of trophoblasts in spontaneous abortion.
GK921, a transglutaminase inhibitor, strengthens the antitumor effect of cisplatin on pancreatic cancer cells by inhibiting epithelial-to-mesenchymal transition.
GIMAP7 inhibits epithelial-mesenchymal transition and glycolysis in lung adenocarcinoma cells via regulating the Smo/AMPK signaling pathway.
M6A reader YTHDF1 promotes malignant progression of laryngeal squamous carcinoma through activating the EMT pathway by EIF4A3.
Tumor suppressor miR-361-3p inhibits prostate cancer progression through Gli1 and AKT/mTOR signaling pathway.
Biomimetic Nanomedicine Targeting Orchestrated Metabolism Coupled with Regulatory Factors to Disrupt the Metabolic Plasticity of Breast Cancer.
SMG9 is a novel prognostic-related biomarker in glioma correlating with ferroptosis and immune infiltrates.
Novel prognostic marker TGFBI affects the migration and invasion function of ovarian cancer cells and activates the integrin αvβ3-PI3K-Akt signaling pathway.
m6A-methylated KCTD21-AS1 regulates macrophage phagocytosis through CD47 and cell autophagy through TIPR.
LncRNA RPARP-AS1 promotes the progression of osteosarcoma cells through regulating lipid metabolism.
The clustering status of detached gastric cancer cells inhibits anoikis-induced ferroptosis to promote metastatic colonization.
Nuclear translocation of cleaved PCDH9 impairs gastric cancer metastasis by downregulating CDH2 expression.
N6-methyladenosine modification of B7-H3 mRNA promotes the development and progression of colorectal cancer.
Bromodomain containing 4 inhibition combats gastric precancerous lesions via modulating macrophage polarization.
ALDH2 attenuates radiation-induced lung injury by inhibiting ROS and epithelial-mesenchymal transition mediated by the TGF-β1/Smad pathway.
RSL3 sensitizes glioma cells to ionizing radiation by suppressing TGM2-dependent DNA damage repair and epithelial-mesenchymal transition.
SLMAP3 is essential for neurulation through mechanisms involving cytoskeletal elements, ABP, and PCP.
CircRNA ITCH Inhibits Epithelial-Mesenchymal Transformation and Promotes Apoptosis in Papillary Thyroid Carcinoma via miR-106a-5p/JAZF1 Axis.
Tabersonine enhances cisplatin sensitivity by modulating Aurora kinase A and suppressing epithelial-mesenchymal transition in triple-negative breast cancer.
Adaptor protein CEMIP reduces the chemosensitivity of small cell lung cancer via activation of an SRC-YAP oncogenic module.
Mediation of circ_0007142 on miR-128-3p/S100A14 pathway to stimulate the progression of cervical cancer.
Dihydroartemisinin enhances the anti-tumour effect of photodynamic therapy by targeting PKM2-mediated glycolysis in oesophageal cancer cell.
Circular RNA circWBSCR22 facilitates colorectal cancer metastasis by enhancing CHD4's protein stability.
Integrative Analysis Identifies NSUN2 as an Essential Coordinator for Glioma Malignancy and Glucose Metabolism.
Quercetin inhibits malignant progression of high metastatic advanced colon cancer in hypoxia via suppressing ROS and PI3K/AKT pathway.
Cardiac Fibroblasts Enhance MMP2 Activity to Suppress Gap Junction Function in Cardiomyocytes.
Corynoxine exerts the anti-tumor effect on esophageal squamous cell carcinoma principally via the EZH2-DUSP5-ERK1/2-mediated cell growth inhibition.
Targeting and degradation of OTUB1 by Erianin for antimetastasis in esophageal squamous cell carcinoma.
RRM2 Regulates Hepatocellular Carcinoma Progression Through Activation of TGF-β/Smad Signaling and Hepatitis B Virus Transcription.
High-fat diet led to testicular inflammation and ferroptosis via dysbiosis of gut microbes.
Mechanistic study of quercetin in the treatment of hepatocellular carcinoma with diabetes via MEK/ERK pathway.
Activin A inhibits the migration of human lung adenocarcinoma A549 cells induced by EGF.
Serine related gene CCT6A promotes metastasis of hepatocellular carcinoma via interacting with RPS3.
Tripartite motif-containing protein 50 suppresses triple-negative breast cancer progression by regulating the epithelial-mesenchymal transition.
RND1 inhibits epithelial-mesenchymal transition and temozolomide resistance of glioblastoma via AKT/GSK3-β pathway.
DNMT1-driven methylation of RORA facilitates esophageal squamous cell carcinoma progression under hypoxia through SLC2A3.
Macropinocytosis inhibits alkaliptosis in pancreatic cancer cells through fatty acid uptake.
Regulation of a novel circATP8B4/miR-31-5p/nestin ceRNA crosstalk in proliferation, motility, invasion and radiosensitivity of human glioma cells.
Exosomes containing circSCP2 in colorectal cancer promote metastasis via sponging miR-92a-1-5p and interacting with PTBP1 to stabilize IGF2BP1.
Machine learning-based prognostic model of lactylation-related genes for predicting prognosis and immune infiltration in patients with lung adenocarcinoma.
Alleviating role of ketamine in breast cancer cell-induced osteoclastogenesis and tumor bone metastasis-induced bone cancer pain through an SRC/EGR1/CST6 axis.
miR-3191 promotes the proliferation and metastasis of hepatocellular carcinoma via regulating PAK6.
Has_circ_0002360 facilitates immune evasion by enhancing heterogeneous nuclear ribonucleoprotein A1 stability, thereby promoting malignant progression in non-small cell lung cancer.
TGFβ2 mediates oxidative stress-induced epithelial-to-mesenchymal transition of bladder smooth muscle.
Dexmedetomidine promotes colorectal cancer progression via Piwil2 signaling.
IFIT1 modulates the proliferation, migration and invasion of pancreatic cancer cells via Wnt/β-catenin signaling.
N6-methyladenosine modified circPAK2 promotes lymph node metastasis via targeting IGF2BPs/VEGFA signaling in gastric cancer.
Autocatalytic, Brain Tumor-Targeting Delivery of Bardoxolone Methyl Self-Assembled Nanoparticles for Glioblastoma Treatment.
Biological effect of ETV4 and the underlying mechanism of its regulatory effect on epithelial‑mesenchymal transition in intrahepatic cholangiocarcinoma cells.
Exosomal miR-130b-3p suppresses metastasis of non-small cell lung cancer cells by targeting DEPDC1 via TGF-β signaling pathway.
P4HA3 promotes head and neck squamous cell carcinoma progression via the WNT/β-catenin signaling pathway.
INPP4B suppresses HER2-induced mesenchymal transition in HER2+ breast cancer and enhances sensitivity to Lapatinib.
Integrated multi-omics profiling landscape of organising pneumonia.
TAGLN2 targeted control of ARPC5-mediated activation of the MEK/ERK signaling pathway influences the proliferation, invasion, and metastasis of pancreatic cancer cells.
An Inherited Allele Confers Prostate Cancer Progression and Drug Resistance via RFX6/HOXA10-Orchestrated TGFβ Signaling.
Aloperine Suppresses Cancer Progression by Interacting with VPS4A to Inhibit Autophagosome-lysosome Fusion in NSCLC.
STC2 suppresses triple-negative breast cancer migration and invasion by inhibition on EMT and promotion on cell apoptosis.
TCF12-regulated GRB7 facilitates the HER2+ breast cancer progression by activating Notch1 signaling pathway.
Hypoxia exacerbates the malignant transformation of gastric epithelial cells induced by long-term H. pylori infection.
OTU deubiquitinase, ubiquitin aldehyde binding 2 (OTUB2) modulates the stemness feature, chemoresistance, and epithelial-mesenchymal transition of colon cancer via regulating GINS complex subunit 1 (GINS1) expression.
Capsaicin combined with cisplatin inhibits TGF-β1-induced EMT and TSCC cells migration via the Claudin-1/PI3K/AKT/mTOR signaling pathway.
Acetylation of PGK1 at lysine 323 promotes glycolysis, cell proliferation, and metastasis in luminal A breast cancer cells.
TRIP13 regulates progression of gastric cancer through stabilising the expression of DDX21.
Catalpol inhibits HHcy-induced EndMT in endothelial cells by modulating ROS/NF-κB signaling.
Does rAj-Tspin, a novel peptide from A. japonicus, exert antihepatocellular carcinoma effects via the ITGB1/ZYX/FAK/AKT signaling pathway?
Pt(iv) derivatives of cisplatin and oxaliplatin bearing an EMT-related TMEM16A/COX-2-selective dual inhibitor against colorectal cancer cells HCT116.
RAE1 promotes gastric carcinogenesis and epithelial-mesenchymal transition.
Campothecin suppresses cell proliferation and migration in head and neck squamous cell carcinoma by blocking RAB27A-mediated phosphatidylinositol 3 kinase (PI3K)/protein kinase B (AKT) pathway.
Kinesin Family Member-18A (KIF18A) Promotes Cell Proliferation and Metastasis in Hepatocellular Carcinoma.
Bone morphogenetic protein 6 (BMP6) antagonises experimental proliferative vitreoretinopathy established by TGF-β2 stimulation in retinal pigment epithelial cells through modulation of the p38 and JNK MAPK pathways.
Propofol-induced LINC01133 inhibits the progression of colorectal cancer via miR-186-5p/NR3C2 axis.
FERMT2 upregulation in CAFs enhances EMT of OSCC and M2 macrophage polarization.
CHL1 inhibits cell proliferation, migration and invasion by regulating the NF‑κB signaling pathway in colorectal cancer.
TGF-β2-induced alterations of m6A methylation in hTERT RPE-1 cells.
A pyrazolopyridine as a novel AhR signaling activator with anti-breast cancer properties in vitro and in vivo.
RETRACTED: High PGC-1α Expression as a Poor Prognostic Indicator in Intracranial Glioma.
Tabersonine Enhances Olaparib Sensitivity through FHL1-Mediated Epithelial-Mesenchymal Transition in an Ovarian Tumor.
DCDC2 inhibits hepatic stellate cell activation and ameliorates CCl(4)-induced liver fibrosis by suppressing Wnt/β-catenin signaling.
Targeting high circDNA2v levels in colorectal cancer induces cellular senescence and elicits an anti-tumor secretome.
N6-methyladenosine-modified circSLCO1B3 promotes intrahepatic cholangiocarcinoma progression via regulating HOXC8 and PD-L1.
The NF-κB/NUAK2 signaling axis regulates pancreatic cancer progression by targeting SMAD2/3.
PRMT6-mediated transcriptional activation of ythdf2 promotes glioblastoma migration, invasion, and emt via the wnt-β-catenin pathway.
Activation of the YY1-UGT2B7 Axis Promotes Mammary Estrogen Homeostasis Dysregulation and Exacerbates Breast Tumor Metastasis.
hsa_circ_0007919 promotes pancreatic cancer metastasis by modulating Sp1-mediated THBS1 transcription.
Hawthorn Proanthocyanidin Extract Inhibits Colorectal Carcinoma Metastasis by Targeting the Epithelial-Mesenchymal Transition Process and Wnt/β-Catenin Signaling Pathway.
Combined therapy of dabrafenib and an anti-HER2 antibody-drug conjugate for advanced BRAF-mutant melanoma.
Adhesive hydrogel releases protocatechualdehyde-Fe(3+) complex to promote three healing stages for accelerated therapy of oral ulcers.
CircGPC3 promotes hepatocellular carcinoma progression and metastasis by sponging miR-578 and regulating RAB7A/PSME3 expression.
Up-regulated SPP1 increases the risk from IPF to lung cancer via activating the pro-tumor macrophages.
The Role of Purine Metabolism-Related Genes PPAT and IMPDH1 in the Carcinogenesis of Intrahepatic Cholangiocarcinoma Based on Metabonomic and Bioinformatic Analyses.
LncRNA SNHG5 Suppresses Cell Migration and Invasion of Human Lung Adenocarcinoma via Regulation of Epithelial-Mesenchymal Transition.
Lnc NR2F1-AS1 Promotes Breast Cancer Metastasis by Targeting the MiR-25-3p/ZEB2 Axis.
Low Expression of GIGYF1 Inhibits Metastasis, Proliferation, and Promotes Apoptosis and Autophagy of Gastric Cancer Cells.
PYGL-mediated glucose metabolism reprogramming promotes EMT phenotype and metastasis of pancreatic cancer.
Timosaponin AIII promotes non-small-cell lung cancer ferroptosis through targeting and facilitating HSP90 mediated GPX4 ubiquitination and degradation.
System analysis identifies UBE2C as a novel oncogene target for adrenocortical carcinoma.
Downregulation of KIAA1199 alleviated the activation, proliferation, and migration of hepatic stellate cells by the inhibition of epithelial-mesenchymal transition.
HDAC5-mediated PRAME regulates the proliferation, migration, invasion, and EMT of laryngeal squamous cell carcinoma via the PI3K/AKT/mTOR signaling pathway.
Exosome-Delivered circSTAU2 Inhibits the Progression of Gastric Cancer by Targeting the miR-589/CAPZA1 Axis.
Escherichia coli Promotes Endothelial to Mesenchymal Transformation of Liver Sinusoidal Endothelial Cells and Exacerbates Nonalcoholic Fatty Liver Disease Via Its Flagellin.
B7 Induces Apoptosis in Colorectal Cancer Cells by Regulating the Expression of Caspase-3 and Inhibits Autophagy.
The cancer/testis antigen HORMAD1 promotes gastric cancer progression by activating the NF-κB signaling pathway and inducing epithelial-mesenchymal transition.
Mannan-Binding Lectin Reduces Epithelial-Mesenchymal Transition in Pulmonary Fibrosis via Inactivating the Store-Operated Calcium Entry Machinery.
ALKBH5-PYCR2 Positive Feedback Loop Promotes Proneural-Mesenchymal Transition Via Proline Synthesis In GBM.
LncRNA HOTAIR Enhances Epithelial-to-mesenchymal Transition to Promote the Migration and Invasion of Liver Cancer by Regulating NUAK1 via Epigenetic Inhibition miR-145-5p Expression.
High SGO2 predicted poor prognosis and high therapeutic value of lung adenocarcinoma and promoted cell proliferation, migration, invasion, and epithelial-to-mesenchymal transformation.
APOC1 exacerbates renal fibrosis through the activation of the NF-κB signaling pathway in IgAN.
A novel prognostic signatures based on metastasis- and immune-related gene pairs for colorectal cancer.
Exploration of epithelial-mesenchymal transition-related lncRNA signature and drug sensitivity in breast cancer.
Apolipoprotein A-I attenuates peritoneal fibrosis associated with peritoneal dialysis by inhibiting oxidative stress and inflammation.
NPM1 promotes nasopharyngeal carcinoma metastasis and stemness by recruiting Mdm2 to induce the ubiquitination-mediated degradation of p53.
ZY-444 inhibits the growth and metastasis of prostate cancer by targeting TNFAIP3 through TNF signaling pathway.
Tocilizumab (monoclonal anti-IL-6R antibody) reverses anlotinib resistance in osteosarcoma.
The deubiquitinating enzyme MINDY2 promotes pancreatic cancer proliferation and metastasis by stabilizing ACTN4 expression and activating the PI3K/AKT/mTOR signaling pathway.
System analysis based on the migration- and invasion-related gene sets identifies the infiltration-related genes of glioma.
EXOSC10 is a novel hepatocellular carcinoma prognostic biomarker: a comprehensive bioinformatics analysis and experiment verification.
VIRMA facilitates intrahepatic cholangiocarcinoma progression through epigenetic augmentation of TMED2 and PARD3B mRNA stabilization.
Estrogens drive the endoplasmic reticulum-associated degradation and promote proto-oncogene c-Myc expression in prostate cancer cells by androgen receptor/estrogen receptor signaling.
ACSL4 promotes ferroptosis and M1 macrophage polarization to regulate the tumorigenesis of nasopharyngeal carcinoma.
Stiff Substrate Induces Nucleus Pulposus Cell Ferroptosis via YAP and N-Cadherin Mediated Mechanotransduction.
Royal jelly acid suppresses hepatocellular carcinoma tumorigenicity by inhibiting H3 histone lactylation at H3K9la and H3K14la sites.
Calycosin inhibits triple-negative breast cancer progression through down-regulation of the novel estrogen receptor-α splice variant ER-α30-mediated PI3K/AKT signaling pathway.
GART Functions as a Novel Methyltransferase in the RUVBL1/β-Catenin Signaling Pathway to Promote Tumor Stemness in Colorectal Cancer.
CBX3 promotes clear cell renal carcinoma through PI3K/AKT activation and aberrant immunity.
Pleckstrin-2 promotes tumour immune escape from NK cells by activating the MT1-MMP-MICA signalling axis in gastric cancer.
Long non-coding RNA MIDEAS-AS1 inhibits growth and metastasis of triple-negative breast cancer via transcriptionally activating NCALD.
DKK1 Promotes Epithelial-Mesenchymal Transition and Cisplatin Resistance in Gastric Cancer via Activation of the PI3K/AKT Pathway.
E-Cadherin Is Expressed in Epithelial Cells of the Choroid Plexus in Human and Mouse Brains.
SPI1-Mediated Upregulation of the CST1 Gene as an Independent Poor Prognostic Factor Accelerates Metastasis in Esophageal Squamous Cell Carcinoma (ESCC) by Interacting with MMP2.
LncRNA CCAT1 facilitates the progression of gastric cancer via PTBP1-mediated glycolysis enhancement.
DSCC1 interacts with HSP90AB1 and promotes the progression of lung adenocarcinoma via regulating ER stress.
Pan-cancer analysis and experimental validation identify ndc1 as a potential immunological, prognostic and therapeutic biomarker in pancreatic cancer.
USP25 promotes hepatocellular carcinoma progression by interacting with TRIM21 via the Wnt/β-catenin signaling pathway.
Progranulin promoted the proliferation, metastasis, and suppressed apoptosis via JAK2-STAT3/4 signaling pathway in papillary thyroid carcinoma.
Circular RNA METTL15/miR-374a-5p/ESCO2 axis induces colorectal cancer development.
N-methylpiperazine-diepoxyovatodiolide ameliorates peritoneal fibrosis via suppressing TGF-β/Smad and JAK/STAT signaling pathway.
Shikonin suppresses small cell lung cancer growth via inducing ATF3-mediated ferroptosis to promote ROS accumulation.
CircUSP10 promotes liver cancer progression by regulating miR-211-5p/TCF12/EMT signaling pathway.
ANKRD22 knockdown suppresses papillary thyroid cell carcinoma growth and migration and modulates the Wnt/β-catenin signaling pathway.
Pingxiao capsule inhibits lung metastasis of triple-negative breast cancer and sensitizes breast cancer to radiotherapy.
Degradation of HIF-1α induced by curcumol blocks glutaminolysis and inhibits epithelial-mesenchymal transition and invasion in colorectal cancer cells.
Pleckstrin homology and RhoGEF domain containing G4 (PLEKHG4) leads to the activation of RhoGTPases promoting the malignant phenotypes of thyroid cancer.
Regulation of the stem‑like properties of estrogen receptor‑positive breast cancer cells through NR2E3/NR2C2 signaling.
Nrf3 promotes the proliferation and migration of triple‑negative breast cancer by activating PI3K/AKT/mTOR and epithelial‑mesenchymal transition.
ACLY promotes gastric tumorigenesis and accelerates peritoneal metastasis of gastric cancer regulated by HIF-1A.
IGF2BP2 promotes glycolysis and hepatocellular carcinoma stemness by stabilizing CDC45 mRNA via m6A modification.
FN1 mediated activation of aspartate metabolism promotes the progression of triple-negative and luminal a breast cancer.
Lemur tyrosine kinase 2 has a tumor-inhibition function in human glioblastoma by regulating the RUNX3/Notch pathway.
UBE2V2 promotes metastasis by regulating EMT and predicts a poor prognosis in lung adenocarcinoma.
Role of Nucleobindin-2 in the Clinical Pathogenesis and Treatment Resistance of Glioblastoma.
Xue-Jie-San prevents the early development of colitis-associated intestinal fibrosis by blocking Notch1 and FGL1 signaling pathways.
Exosome-transported circHDAC1_004 Promotes Proliferation, Migration, and Angiogenesis of Hepatocellular Carcinoma by the miR-361-3p/NACC1 Axis.
CYP19A1 promotes gastric cancer as part of a lipid metabolism-related gene signature related to the response of immunotherapy and prognosis.
Eriocitrin inhibits epithelial-mesenchymal transformation (EMT) in lung adenocarcinoma cells via triggering ferroptosis.
Dendrobium officinale polysaccharide Converts M2 into M1 Subtype Macrophage Polarization via the STAT6/PPAR-r and JAGGED1/NOTCH1 Signaling Pathways to Inhibit Gastric Cancer.
Exploring the anticancer potential of Actinidia chinensis Planch root extracts (acRoots) on hepatocellular carcinoma: A molecular mechanism study.
The PI3K-AKT-mTOR signaling pathway mediates the cytoskeletal remodeling and epithelial-mesenchymal transition in bladder outlet obstruction.
TRIM16 E121D variant affects the risk and prognosis of hepatocellular carcinoma by modulating the Wnt/β-catenin pathway.
Circ_0001589/miR-1248/HMGB1 axis enhances EMT-mediated metastasis and cisplatin resistance in cervical cancer.
Macrophage microvesicle-derived circ_YTHDF2 in methamphetamine-induced chronic lung injury.
BMP4 Regulates EMT to be Involved in non-Syndromic Cleft lip With or Without Palate.
RNA‑binding protein quaking 5 inhibits the progression of non‑small cell lung cancer by upregulating netrin‑4 expression.
RUNX1 promotes proliferation and migration in non-small cell lung cancer cell lines via the mTOR pathway.
Comprehensive analysis of P2Y family genes expression, immune characteristics, and prognosis in pan-cancer.
PCSK9 promotes tumor cell proliferation and migration by facilitating CCL25 secretion in esophageal squamous cell carcinoma.
B4GALNT1 promotes carcinogenesis by regulating epithelial-mesenchymal transition in hepatocellular carcinoma based on pan-cancer analysis.
Autophagy regulation and protein kinase activity of PIK3C3 controls sertoli cell polarity through its negative regulation on SCIN (scinderin).
Hyperbranched polyamidoamine-RGD peptide/si-circICA1 in the treatment of invasive thyroid cancer through targeting of the miR-486-3p/SERPINA1 axis.
CTRP6 regulates M1 macrophage polarization via the PPAR-γ/NF-κB pathway and reprogramming glycolysis in recurrent spontaneous abortion.
Icaritin inhibits endometrial carcinoma cells by suppressing O-GlcNAcylation of FOXC1.
A novel c-Met/TRK inhibitor 1D228 efficiently inhibits tumor growth by targeting angiogenesis and tumor cell proliferation.
Platycodin D inhibits glioblastoma cell proliferation, migration, and invasion by regulating DEPDC1B-mediated epithelial-to-mesenchymal transition.
Discovery of a novel dual-target inhibitor of CDK12 and PARP1 that induces synthetic lethality for treatment of triple-negative breast cancer.
Ag/TiO(2) nanohybrids induce fibrosis-related epithelial-mesenchymal transition in lung epithelial cells and the influences of silver content and silver particle size.
Synergistic anti-tumour activity of ginsenoside Rg3 and doxorubicin on proliferation, metastasis and angiogenesis in osteosarcoma by modulating mTOR/HIF-1α/VEGF and EMT signalling pathways.
STIM2 regulates NMDA receptor endocytosis that is induced by short-term NMDA receptor overactivation in cortical neurons.
LMP2 and TAP2 impair tumor growth and metastasis by inhibiting Wnt/β-catenin signaling pathway and EMT in cervical cancer.
FAM171B stabilizes vimentin and enhances CCL2-mediated TAM infiltration to promote bladder cancer progression.
Curcumin Disrupts a Positive Feedback Loop between ADMSCs and Cancer Cells in the Breast Tumor Microenvironment via the CXCL12/CXCR4 Axis.
IGFBP2 drives epithelial-mesenchymal transition in hepatocellular carcinoma via activating the Wnt/β-catenin pathway.
GAD1-mediated GABA elicits aggressive characteristics of human oral cancer cells.
Lnc AC016727.1/BACH1/HIF-1 α signal loop promotes the progression of non-small cell lung cancer.
The HDAC inhibitor HFY-4A improves TUSC2 transcription to induce immunogenic cell death in breast cancer.
Piezoeletric cold atmospheric plasma induces apoptosis and autophagy in human hepatocellular carcinoma cells through blocking glycolysis and AKT/mTOR/HIF-1α pathway.
Suprabasin enhances the invasion, migration, and angiogenic ability of oral squamous cell carcinoma cells under hypoxic conditions.
Naringenin in Si-Ni-San formula inhibits chronic psychological stress-induced breast cancer growth and metastasis by modulating estrogen metabolism through FXR/EST pathway.
MAP4K4 promotes ovarian cancer metastasis through diminishing ADAM10-dependent N-cadherin cleavage.
ADAM12 promotes gemcitabine resistance by activating EGFR signaling pathway and induces EMT in bladder cancer.
Deciphering the Clinical Significance and Kinase Functions of GSK3α in Colon Cancer by Proteomics and Phosphoproteomics.
Phenotypic Heterogeneity Analysis of APC-Mutant Colon Cancer by Proteomics and Phosphoproteomics Identifies RAI14 as a Key Prognostic Determinant in East Asians and Westerners.
BZW1 as an oncogene is associated with patient prognosis and the immune microenvironment in glioma.
The NR_109/FUBP1/c-Myc axis regulates TAM polarization and remodels the tumor microenvironment to promote cancer development.
MicroRNA-150-5p inhibits the proliferation and invasion of human larynx epidermiod cancer cells though regulating peptidyl-prolyl cis/trans isomerase.
High Level of GMFG Correlated to Poor Clinical Outcome and Promoted Cell Migration and Invasion through EMT Pathway in Triple-Negative Breast Cancer.
NEK2 promotes esophageal squamous cell carcinoma cell proliferation, migration and invasion through the Wnt/β-catenin signaling pathway.
PRMT2 promotes RCC tumorigenesis and metastasis via enhancing WNT5A transcriptional expression.
Growth and Migration Blocking Effect of Nanaomycin K, a Compound Produced by Streptomyces sp., on Prostate Cancer Cell Lines In Vitro and In Vivo.
Decreasing expression of Prohibitin-2 lowers the oncogenicity of renal cell carcinoma cells by suppressing eIF4E-mediated oncogene translation via MNK inhibition.
KIFC3 regulates progression of hepatocellular carcinoma via EMT and the AKT/mTOR pathway.
The role of ferroptosis mediated by Bmal1/Nrf2 in nicotine -induce injury of BTB integrity.
Thiol oxidative stress-dependent degradation of transglutaminase2 via protein S-glutathionylation sensitizes 5-fluorouracil therapy in 5-fluorouracil-resistant colorectal cancer cells.
miR‑151a‑5p promotes the proliferation and metastasis of colorectal carcinoma cells by targeting AGMAT.
Circ_0056618 enhances PRRG4 expression by competitively binding to miR-411-5p to promote the malignant progression of colorectal cancer.
CircNDST1 promotes papillary thyroid cancer progression via its interaction with CSNK2A1 to activate the PI3K-Akt pathway and epithelial-mesenchymal transition.
Silencing RPL8 inhibits the progression of hepatocellular carcinoma by down-regulating the mTORC1 signalling pathway.
STMN2 overexpression promotes cell proliferation and EMT in pancreatic cancer mediated by WNT/β-catenin signaling.
Cyclin-dependent kinase subunit2 (CKS2) promotes malignant phenotypes and epithelial-mesenchymal transition-like process in glioma by activating TGFβ/SMAD signaling.
1,25(OH)(2) D(3) induced vitamin D receptor signaling negatively regulates endoplasmic reticulum-associated degradation (ERAD) and androgen receptor signaling in human prostate cancer cells.
The Enzyme 15-Hydroxyprostaglandin Dehydrogenase Inhibits a Shift to the Mesenchymal Pattern of Trophoblasts and Decidual Stromal Cells Accompanied by Prostaglandin Transporter in Preeclampsia.
HSPA5 Promotes the Proliferation, Metastasis and Regulates Ferroptosis of Bladder Cancer.
CPT1A modulates PI3K/Akt/mTOR pathway to promote preeclampsia.
Demethylase FTO enhances the PI3K/Akt signaling to promote gastric cancer malignancy.
Fatostatin induces ferroptosis through inhibition of the AKT/mTORC1/GPX4 signaling pathway in glioblastoma.
NONHSAT021545/miR-330-3p/EREG: A Cooperative Axis in Breast Cancer Prognosis and Treatment.
PRAME Promotes Cervical Cancer Proliferation and Migration via Wnt/β-Catenin Pathway Regulation.
F-box and leucine-rich repeat 6 promotes gastric cancer progression via the promotion of epithelial-mesenchymal transition.
Downregulation of PSAT1 inhibits cell proliferation and migration in uterine corpus endometrial carcinoma.
TMEM2 induces epithelial-mesenchymal transition and promotes resistance to temozolomide in GBM cells.
Potent carotenoid astaxanthin expands the anti-cancer activity of cisplatin in human prostate cancer cells.
PDK1 regulates the progression of esophageal squamous cell carcinoma through metabolic reprogramming.
ZNF133 is a potent suppressor in breast carcinogenesis through dampening L1CAM, a driver for tumor progression.
Meso-Hannokinol inhibits breast cancer bone metastasis via the ROS/JNK/ZEB1 axis.
Loss of exosomal miR-200b-3p from hypoxia cancer-associated fibroblasts promotes tumorigenesis and reduces sensitivity to 5-Flourouracil in colorectal cancer via upregulation of ZEB1 and E2F3.
SETDB1 induces lenalidomide resistance in multiple myeloma cells via epithelial‑mesenchymal transition and PI3K/AKT pathway activation.
HnRNPAB is an independent prognostic factor in non‑small cell lung cancer and is involved in cell proliferation and metastasis.
Targeting HMGA1 contributes to immunotherapy in aggressive breast cancer while suppressing EMT.
LINC01116 modulates EMT process via binding with AGO1 mRNA in oesophageal squamous cell carcinoma.
Squalene epoxidase promotes hepatocellular carcinoma development by activating STRAP transcription and TGF-β/SMAD signalling.
NPTX2 Promotes Epithelial-Mesenchymal Transition in Cutaneous Squamous Cell Carcinoma through METTL3-Mediated N6-Methyladenosine Methylation of SNAIL.
TRIM55 inhibits colorectal cancer development via enhancing protein degradation of c-Myc.
MED27 plays a tumor-promoting role in breast cancer progression by targeting KLF4.
MTAP-ANRIL gene fusion promotes melanoma epithelial-mesenchymal transition-like process by activating the JNK and p38 signaling pathways.
SIAH1/CTR9 axis promotes the epithelial-mesenchymal transition of hepatocellular carcinoma.
FBXO28 promotes proliferation, invasion, and metastasis of pancreatic cancer cells through regulation of SMARCC2 ubiquitination.
ORP8 inhibits renal cell carcinoma progression by accelerating Stathmin1 degradation and microtubule polymerization.
Arsenic interferes with spermatogenesis involving Rictor/mTORC2-mediated blood-testis barrier disruption in mice.
Network pharmacology, molecular docking and experimental verification help unravel chelerythrine's potential mechanism in the treatment of gastric cancer.
MRPL51 is a downstream target of FOXM1 in promoting the malignant behaviors of lung adenocarcinoma.
Analysis and validation of the potential of the MYO1E gene in pancreatic adenocarcinoma based on a bioinformatics approach.
TANGO1 interacts with NRTN to promote hepatocellular carcinoma progression by regulating the PI3K/AKT/mTOR signaling pathway.
Disordered gut microbiota promotes atrial fibrillation by aggravated conduction disturbance and unbalanced linoleic acid/SIRT1 signaling.
SIRT3-mediated autophagy contributes to ferroptosis-induced anticancer by inducing the formation of BECN1-SLC7A11 complex.
Genome-wide CRISPR knockout screening identified G protein pathway suppressor 2 as a novel tumor suppressor for uveal melanoma metastasis.
The role of DYNLT3 in breast cancer proliferation, migration, and invasion via epithelial-to-mesenchymal transition.
Pan-cancer analysis of oncogenic role of insulin-like growth factor-binding proteins and validation in ovarian cancer.
HERPUD1, a Member of the Endoplasmic Reticulum Protein Quality Control Mechanism, may be a Good Target for Suppressing Tumorigenesis in Breast Cancer Cells.
The promoting effect and mechanism of Nrf2 on cell metastasis in cervical cancer.
Schwann cells regulate tumor cells and cancer-associated fibroblasts in the pancreatic ductal adenocarcinoma microenvironment.
Luteolin inhibits subretinal fibrosis and epithelial-mesenchymal transition in laser-induced mouse model via suppression of Smad2/3 and YAP signaling.
Lnc-LRRTM4 promotes proliferation, metastasis and EMT of colorectal cancer through activating LRRTM4 transcription.
Fibronectin promotes tumor angiogenesis and progression of non-small-cell lung cancer by elevating WISP3 expression via FAK/MAPK/ HIF-1α axis and activating wnt signaling pathway.
NCOA7 Regulates Growth and Metastasis of Clear Cell Renal Cell Carcinoma via MAPK/ERK Signaling Pathway.
PLAGL2 promotes bladder cancer progression via RACGAP1/RhoA GTPase/YAP1 signaling.
Long noncoding RNA LINC01594 inhibits the CELF6-mediated splicing of oncogenic CD44 variants to promote colorectal cancer metastasis.
AFP deletion leads to anti-tumorigenic but pro-metastatic roles in liver cancers with concomitant CTNNB1 mutations.
Knockdown of ABCB7 inhibits esophageal cancer progression by inhibiting the TGF-β/Smad signaling.
Biochemical and clinical effects of RPS20 expression in renal clear cell carcinoma.
Resveratrol reverses TGF-β1-mediated invasion and metastasis of breast cancer cells via the SIRT3/AMPK/autophagy signal axis.
Formin protein DIAPH1 positively regulates PD-L1 expression and predicts the therapeutic response to anti-PD-1/PD-L1 immunotherapy.
Exosomal miR-543 derived from umbilical cord mesenchymal stem cells ameliorates endometrial fibrosis in intrauterine adhesion via downregulating N-cadherin.
Multiomics analyses and machine learning of nuclear receptor coactivator 6 reveal its essential role in hepatocellular carcinoma.
Hypermethylation-Mediated lncRNA MAGI2-AS3 Downregulation Facilitates Malignant Progression of Laryngeal Squamous Cell Carcinoma via Interacting With SPT6.
Lactoferrin Restores the Deoxynivalenol-Impaired Spermatogenesis and Blood-Testis Barrier Integrity via Improving the Antioxidant Capacity and Modifying the Cell Adhesion and Inflammatory Response.
5'-tRF-GlyGCC promotes breast cancer metastasis by increasing fat mass and obesity-associated protein demethylase activity.
Glycolysis-Related Gene Analyses Indicate That DEPDC1 Promotes the Malignant Progression of Oral Squamous Cell Carcinoma via the WNT/β-Catenin Signaling Pathway.
Hypoxia-induced ROS aggravate tumor progression through HIF-1α-SERPINE1 signaling in glioblastoma.
Molecular mechanism of the miR-7/BCL2L1/P53 signaling axis regulating the progression of hepatocellular carcinoma.
FRMD3 inhibits the growth and metastasis of breast cancer through the ubiquitination-mediated degradation of vimentin and subsequent impairment of focal adhesion.
CMTM6 overexpression confers trastuzumab resistance in HER2-positive breast cancer.
High expression of NLRP12 predicts poor prognosis in patients with intracranial glioma.
Etomidate elicits anti-tumor capacity by disrupting the JAK2/STAT3 signaling pathway in hepatocellular carcinoma.
A2aR inhibits fibrosis and the EMT process in silicosis by regulating Wnt/β-catenin pathway.
MALAT1-miR-30c-5p-CTGF/ATG5 axis regulates silica-induced experimental silicosis by mediating EMT in alveolar epithelial cells.
The TGF-β/Smad(2/3) signaling pathway is involved in Musashi2-induced invasion and metastasis of colorectal cancer.
Silencing CircEIF3I/miR-526b-5p Axis Epigenetically Targets HGF/c-Met Signal to Hinder the Malignant Growth, Metastasis and Angiogenesis of Hepatocellular Carcinoma.
Novel long noncoding RNA LINC02820 augments TNF signaling pathway to remodel cytoskeleton and potentiate metastasis in esophageal squamous cell carcinoma.
LIM and Cysteine-Rich Domains 1 Promotes Transforming Growth Factor β1-Induced Epithelial-Mesenchymal Transition in Human Kidney 2 Cells.
RRP15 deficiency induces ribosome stress to inhibit colorectal cancer proliferation and metastasis via LZTS2-mediated β-catenin suppression.
Secretome of hESC-Derived MSC-like Immune and Matrix Regulatory Cells Mitigate Pulmonary Fibrosis through Antioxidant and Anti-Inflammatory Effects.
Serum Response Factor-Regulated IDO1/Kyn-Ahr Pathway Promotes Tumorigenesis of Oral Squamous Cell Carcinoma.
The malignancy of chordomas is enhanced via a circTLK1/miR-16-5p/Smad3 positive feedback axis.
METTL3 depletion contributes to tumour progression and drug resistance via N6 methyladenosine-dependent mechanism in HR+HER2-breast cancer.
CircPTK2/PABPC1/SETDB1 axis promotes EMT-mediated tumor metastasis and gemcitabine resistance in bladder cancer.
Exosomes derived from human umbilical cord mesenchymal stem cells loaded with RVG-Lamp2b and Netrin-1 promotes Schwann cell invasion and migration.
AKAP12 inhibits esophageal squamous carcinoma cell proliferation, migration, and cell cycle via the PI3K/AKT signaling pathway.
Loke zupa decoction attenuates bronchial EMT-mediated airway remodelling in chronic asthma through the PI3K-Akt/HIF-1α signaling pathway.
Mechanisms of dihydromyricetin against hepatocellular carcinoma elucidated by network pharmacology combined with experimental validation.
Abnormal activation of the Wnt3a/β-catenin signaling pathway promotes the expression of T-box transcription factor 3(TBX3) and the epithelial-mesenchymal transition pathway to mediate the occurrence of adenomyosis.
Transcriptome sequencing identifies prognostic genes involved in gastric adenocarcinoma.
Selumetinib overcomes gefitinib primary and acquired resistance by regulating MIG6/STAT3 in NSCLC.
Brusatol enhances MEF2A expression to inhibit RCC progression through the Wnt signalling pathway in renal cell carcinoma.
ACTN1 promotes HNSCC tumorigenesis and cisplatin resistance by enhancing MYH9-dependent degradation of GSK-3β and integrin β1-mediated phosphorylation of FAK.
RUNX1 knockdown induced apoptosis and impaired EMT in high-grade serous ovarian cancer cells.
Sinapine thiocyanate exhibited anti-colorectal cancer effects by inhibiting KRT6A/S100A2 axis.
VAMP8 suppresses the metastasis via DDX5/β-catenin signal pathway in osteosarcoma.
Inhibition of TGF-β1-induced epithelial-mesenchymal transition in gliomas by DMC-HA.
ALOX5 acts as a key role in regulating the immune microenvironment in intrahepatic cholangiocarcinoma, recruiting tumor-associated macrophages through PI3K pathway.
GABA induced by sleep deprivation promotes the proliferation and migration of colon tumors through miR-223-3p endogenous pathway and exosome pathway.
Therapeutic protein PAK restrains the progression of triple negative breast cancer through degrading SREBP-1 mRNA.
Dissecting T-cell heterogeneity in esophageal squamous cell carcinoma reveals the potential role of LAIR2 in antitumor immunity.
Squalene epoxidase promotes breast cancer progression by regulating CCNB1 protein stability.
Ginsenoside Rg1 Alleviates Lipopolysaccharide-Induced Fibrosis of Endometrial Epithelial Cells in Dairy Cows by Inhibiting Reactive Oxygen Species-Activated NLRP3.
TAGLN2 Promotes the Proliferation, Migration, Invasion, and EMT of Clear Cell Renal Cell Carcinoma Through the PI3K/Akt Signaling Pathway.
KIF15 knockdown inhibits the development of endometrial cancer by suppressing epithelial-mesenchymal transition and stemness through Wnt/β-catenin signaling.
High SNRPA1 expression leads to poor prognosis in patients with lung adenocarcinoma.
Combined effects of vitamin D and neferine on the progression and metastasis of colorectal cancer.
Long non-coding RNA ENST00000503625 is a potential prognostic biomarker and metastasis suppressor gene in prostate cancer.
Inhibition of IL-4/STAT6/IRF4 signaling reduces the epithelial-mesenchymal transition in eosinophilic chronic rhinosinusitis with nasal polyps.
ZDHHC11B is decreased in lung adenocarcinoma and inhibits tumorigenesis via regulating epithelial-mesenchymal transition.
Hypoxic tumor-derived exosomal miR-21 induces cancer-associated fibroblast activation to promote head and neck squamous cell carcinoma metastasis.
SMC1A facilitates gastric cancer cell proliferation, migration, and invasion via promoting SNAIL activated EMT.
High Thioredoxin Domain-Containing Protein 11 Expression Is Associated with Tumour Progression in Glioma.
Acetyl-cinobufagin suppresses triple-negative breast cancer progression by inhibiting the STAT3 pathway.
Orosomucoid 1 promotes colorectal cancer progression and liver metastasis by affecting PI3K/AKT pathway and inducing macrophage M2 polarization.
Underlying Molecular Mechanism and Construction of a miRNA-Gene Network in Idiopathic Pulmonary Fibrosis by Bioinformatics.
CXCL8 Promotes Endothelial-to-Mesenchymal Transition of Endothelial Cells and Protects Cells from Erastin-Induced Ferroptosis via CXCR2-Mediated Activation of the NF-κB Signaling Pathway.
PHF23 promotes NSCLC proliferation, metastasis, and chemoresistance via stabilization of ACTN4 and activation of the ERK pathway.
PNU-74654 Induces Cell Cycle Arrest and Inhibits EMT Progression in Pancreatic Cancer.
Transforms of Cell Surface Glycoproteins Charge Influences Tumor Cell Metastasis via Atypically Inhibiting Epithelial-Mesenchymal Transition Including Matrix Metalloproteinases and Cell Junctions.
ADAMDEC1 induces EMT and promotes colorectal cancer cells metastasis by enhancing Wnt/β-catenin signaling via negative modulation of GSK-3β.
Claudin-3 facilitates the progression and mediates the tumorigenic effects of TGF-β in glioblastoma multiforme.
Ubiquitin-specific protease 7 prevents recurrent spontaneous abortion by targeting enhancer of zeste homolog 2 to regulate trophoblast proliferation, apoptosis, migration, and invasion through the Wnt/β-catenin pathway†.
Tumor cells-derived exosomal PD-L1 promotes the growth and invasion of lung cancer cells in vitro via mediating macrophages M2 polarization.
Mitochondrial division inhibitor (mdivi-1) inhibits proliferation and epithelial-mesenchymal transition via the NF-κB pathway in thyroid cancer cells.
Thrombospondin-1 mimic peptide PKHB1 induced endoplasmic reticulum stress-mediated but CD47-independent apoptosis in non-small cell lung cancer.
Circular RNA Sec61 subunit alpha isoform 1 by competitive absorption of microRNA-513a-5p mediates peroxisomal biogenesis factor 5 expression and promotes the malignant phenotype of non-small cell lung cancer.
The aryl sulfonamide indisulam inhibits gastric cancer cell migration by promoting the ubiquitination and degradation of the transcription factor ZEB1.
ADAMTS12 promotes migration and epithelial-mesenchymal transition and predicts poor prognosis for pancreatic cancer.
Budding uninhibited by benzimidazoles 1 overexpression is associated with poor prognosis and malignant phenotype: A promising therapeutic target for lung adenocarcinoma.
ETV4 Mediated Tumor-Associated Neutrophil Infiltration Facilitates Lymphangiogenesis and Lymphatic Metastasis of Bladder Cancer.
Radiation induces IRAK1 expression to promote radioresistance by suppressing autophagic cell death via decreasing the ubiquitination of PRDX1 in glioma cells.
ZSWIM1 Promotes the Proliferation and Metastasis of Lung Adenocarcinoma Cells through the STK38/MEKK2/ERK1/2 Axis.
Melatonin induces cell cycle arrest and suppresses tumor invasion in urinary bladder urothelial carcinoma.
USP1 modulates hepatocellular carcinoma progression via the Hippo/TAZ axis.
LINC00365 functions as a tumor suppressor by inhibiting HIF-1α-mediated glucose metabolism reprogramming in breast cancer.
Aristolochic acid I promotes the invasion and migration of hepatocellular carcinoma cells by activating the C3a/C3aR complement system.
Classification of the mitochondrial ribosomal protein-associated molecular subtypes and identified a serological diagnostic biomarker in hepatocellular carcinoma.
Non-canonical Small GTPase RBJ Promotes NSCLC Progression Through the Canonical MEK/ERK Signaling Pathway.
Carbon Monoxide-Releasing Molecule-3 Suppresses the Malignant Biological Behavior of Tongue Squamous Cell Carcinoma via Regulating Keap1/Nrf2/HO-1 Signaling Pathway.
PHGDH Inhibitor CBR-5884 Inhibits Epithelial Ovarian Cancer Progression via ROS/Wnt/β-Catenin Pathway and Plays a Synergistic Role with PARP Inhibitor Olaparib.
Keratin 8 Is an Inflammation-Induced and Prognosis-Related Marker for Pancreatic Adenocarcinoma.
JPHYD Inhibits miR-21-5p/Smad7-Mediated Epithelial-Mesenchymal Transition of Hepatocellular Carcinoma Cells.
Xiaotan Sanjie Decoction Inhibits Gastric Cancer Cell Proliferation, Migration, and Invasion through lncRNA-ATB and miR-200A.
Comprehensive Pan-Cancer Analysis of IRAK Family Genes Identifies IRAK1 as a Novel Oncogene in Low-Grade Glioma.
Multifunctional Drug-Loaded Phase-Change Nanoparticles Inhibit the Epithelial-Mesenchymal Transition of Hepatocellular Carcinoma by Affecting the Activity of Activated Hepatic Stellate Cells.
TNFAIP6 Promotes Gastric Carcinoma Cell Invasion via Upregulating PTX3 and Activating the Wnt/β-Catenin Signaling Pathway.
ASPM Promotes the Progression of Anaplastic Thyroid Carcinomas by Regulating the Wnt/β-Catenin Signaling Pathway.
CYP26A1 Is a Novel Cancer Biomarker of Pancreatic Carcinoma: Evidence from Integration Analysis and In Vitro Experiments.
DSC2 Suppresses the Metastasis of Gastric Cancer through Inhibiting the BRD4/Snail Signaling Pathway and the Transcriptional Activity of β-Catenin.
Prognostic Lnc-S100B-2 Affects Cell Apoptosis and Microenvironment of Colorectal Cancer through MLLT10 Signaling.
Biochanin A Suppresses Tumor Progression and PD-L1 Expression via Inhibiting ZEB1 Expression in Colorectal Cancer.
Upregulated LINC00922 Promotes Epithelial-Mesenchymal Transition and Indicates a Dismal Prognosis in Gastric Cancer.
Novel lncRNA AL033381.2 Promotes Hepatocellular Carcinoma Progression by Upregulating PRKRA Expression.
ROS Promote Hypoxia-Induced Keratinocyte Epithelial-Mesenchymal Transition by Inducing SOX2 Expression and Subsequent Activation of Wnt/β-Catenin.
Spheroid Formation Enhances the Regenerative Capacity of Nucleus Pulposus Cells via Regulating N-CDH and ITGβ1 Interaction.
UBE2S as a novel ubiquitinated regulator of p16 and β-catenin to promote bone metastasis of prostate cancer.
USP1 inhibition suppresses the progression of osteosarcoma via destabilizing TAZ.
Minocycline binds and inhibits LYN activity to prevent STAT3-meditated metastasis of colorectal cancer.
Decrease of circARID1A retards glioblastoma invasion by modulating miR-370-3p/ TGFBR2 pathway.
Interaction between BEND5 and RBPJ suppresses breast cancer growth and metastasis via inhibiting Notch signaling.
Commensal microbe-derived SCFA alleviates atrial fibrillation via GPR43/NLRP3 signaling.
Smurf2 suppresses the metastasis of hepatocellular carcinoma via ubiquitin degradation of Smad2.
Clotrimazole Inhibits HCC Migration and Invasion by Modulating the ERK-p65 Signaling Pathway.
TMEM158 Regulates the Canonical and Non-Canonical Pathways of TGF-β to Mediate EMT in Triple-Negative Breast Cancer.
Aberrant Expression of BUB1B Contributes to the Progression of Thyroid Carcinoma and Predicts Poor Outcomes for Patients.
Sinapine Thiocyanate Inhibits the Proliferation and Mobility of Pancreatic Cancer Cells by Up-Regulating GADD45A.
NRF2-directed PRPS1 upregulation to promote the progression and metastasis of melanoma.
Endoglin aggravates peritoneal fibrosis by regulating the activation of TGF-β/ALK/Smads signaling.
IL-22 regulates endometrial regeneration by enhancing tight junctions and orchestrating extracellular matrix.
A comprehensively prognostic and immunological analysis of actin-related protein 2/3 complex subunit 5 in pan-cancer and identification in hepatocellular carcinoma.
Crosstalk of Histone and RNA Modifications Identified a Stromal-Activated Subtype with Poor Survival and Resistance to Immunotherapy in Gastric Cancer.
KIFC3 Promotes Proliferation, Migration, and Invasion in Colorectal Cancer via PI3K/AKT/mTOR Signaling Pathway.
Comprehensive analysis of a glycolysis and cholesterol synthesis-related genes signature for predicting prognosis and immune landscape in osteosarcoma.
Dysfunction of CCR1(+) decidual macrophages is a potential risk factor in the occurrence of unexplained recurrent pregnancy loss.
COA3 overexpression promotes non-small cell lung cancer metastasis by reprogramming glucose metabolism.
The homeostatic malfunction of a novel feedback pathway formed by lncRNA021545, miR-330-3p and epiregulin contributes in hepatocarcinoma progression via mediating epithelial-mesenchymal transition.
Decreased RNA m(6)A methylation enhances the process of the epithelial mesenchymal transition and vasculogenic mimicry in glioblastoma.
Interleukin-17 promotes the development of ovarian cancer through upregulation of MTA1 expression.
A novel epithelial-mesenchymal transition (EMT)-related gene signature of predictive value for the survival outcomes in lung adenocarcinoma.
Novel LncRNA ZFHX4-AS1 as a Potential Prognostic Biomarker That Affects the Immune Microenvironment in Ovarian Cancer.
Knockdown of USP8 inhibits prostate cancer cell growth, proliferation, and metastasis and promotes docetaxel's activity by suppressing the NF-kB signaling pathway.
HPV16 E6-Activated OCT4 Promotes Cervical Cancer Progression by Suppressing p53 Expression via Co-Repressor NCOR1.
OCT4 induces EMT and promotes ovarian cancer progression by regulating the PI3K/AKT/mTOR pathway.
Chordin-Like 1 Regulates Epithelial-to-Mesenchymal Transition and Metastasis via the MAPK Signaling Pathway in Oral Squamous Cell Carcinoma.
Integrated Network Pharmacology and Experimental Verification to Explore the Molecular Mechanism of Hedysarum Multijugum Maxim-Curcumae Rhizoma Herb Pair for Treating Non-Small Cell Lung Cancer.
ACADL Functions as a Tumor Suppressor in Hepatocellular Carcinoma Metastasis by Inhibiting Matrix Metalloproteinase 14.
Analysis of L Antigen Family Member 3 as a Potential Biomarker and Therapeutic Target Associated With the Progression of Hepatocellular Carcinoma.
NUF2 Expression Promotes Lung Adenocarcinoma Progression and Is Associated With Poor Prognosis.
Syntenin Regulated by miR-216b Promotes Cancer Progression in Pancreatic Cancer.
N-Glycosylation at Asn291 Stabilizes TIM-4 and Promotes the Metastasis of NSCLC.
GNG12 as A Novel Molecular Marker for the Diagnosis and Treatment of Glioma.
Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta gene as a tumour suppressor in stomach adenocarcinoma.
Prognostic biomarker MCP-4 triggers epithelial-mesenchymal transition via the p38 MAPK pathway in ovarian cancer.
Consistent downregulation of the cleft lip/palate-associated genes IRF6 and GRHL3 in carcinomas.
Loss of CMTM6 promotes DNA damage-induced cellular senescence and antitumor immunity.
Sophocarpine inhibits tumor progression by antagonizing the PI3K/AKT/mTOR signaling pathway in castration-resistant prostate cancer.
CircFGGY Inhibits Cell Growth, Invasion and Epithelial-Mesenchymal Transition of Hepatocellular Carcinoma via Regulating the miR-545-3p/Smad7 Axis.
Targeting MALT1 Suppresses the Malignant Progression of Colorectal Cancer via miR-375/miR-365a-3p/NF-κB Axis.
Maintenance of multipotency of bone marrow mesenchymal stem cells on poly(ε-caprolactone) nanoneedle arrays through the enhancement of cell-cell interaction.
Heat stress and hypoxia inhibit the secretion of androgens and induce epithelial-to-mesenchymal transition associated with activated TGF-β/Smad signalling in canine cryptorchidism.
Irisin/FNDC5 inhibits the epithelial-mesenchymal transition of epithelial ovarian cancer cells via the PI3K/Akt pathway.
GTSE1 promotes tumor growth and metastasis by attenuating of KLF4 expression in clear cell renal cell carcinoma.
TFAP2C Knockdown Sensitizes Bladder Cancer Cells to Cisplatin Treatment via Regulation of EGFR and NF-κB.
HOXA5 inhibits the proliferation of extrahepatic cholangiocarcinoma cells by enhancing MXD1 expression and activating the p53 pathway.
NR2F1 Regulates TGF-β1-Mediated Epithelial-Mesenchymal Transition Affecting Platinum Sensitivity and Immune Response in Ovarian Cancer.
Taraxasterol Inhibits Tumor Growth by Inducing Apoptosis and Modulating the Tumor Microenvironment in Non-Small Cell Lung Cancer.
AHSA1 Promotes Proliferation and EMT by Regulating ERK/CALD1 Axis in Hepatocellular Carcinoma.
Genistein Restricts the Epithelial Mesenchymal Transformation (EMT) and Stemness of Hepatocellular Carcinoma via Upregulating miR-1275 to Inhibit the EIF5A2/PI3K/Akt Pathway.
Alcohol promotes epithelial mesenchymal transformation-mediated premetastatic niche formation of colorectal cancer by activating interaction between laminin-γ2 and integrin-β1.
KCTD9 inhibits the Wnt/β-catenin pathway by decreasing the level of β-catenin in colorectal cancer.
Inhibition of PTPN21 has antitumor effects in glioma by restraining the EGFR/PI3K/AKT pathway.
Label-free detection and enumeration of rare circulating tumor cells by bright-field image cytometry and multi-frame image correlation analysis.
Hypoxia-induced polarization of M2 macrophages and C-C motif chemokine ligand 5 secretion promotes the migration and invasion of trophoblasts†.
Amphiphilic Aminated Derivatives of [60]Fullerene as Potent Inhibitors of Tumor Growth and Metastasis.
Exosomes derived from mesenchymal stem cells attenuate diabetic kidney disease by inhibiting cell apoptosis and epithelial-to-mesenchymal transition via miR-424-5p.
Identification of a five m6A-relevant mRNAs signature and risk score for the prognostication of gastric cancer.
Transfer RNA-derived fragment 5'tRF-Gly promotes the development of hepatocellular carcinoma by direct targeting of carcinoembryonic antigen-related cell adhesion molecule 1.
Natural shikonin and acetyl-shikonin improve intestinal microbial and protein composition to alleviate colitis-associated colorectal cancer.
Tension of plus-end tracking protein Clip170 confers directionality and aggressiveness during breast cancer migration.
ALG3 Promotes Peritoneal Metastasis of Ovarian Cancer through Increasing Interaction of α1,3-mannosylated uPAR and ADAM8.
IGF2BP2 Promotes Epithelial to Mesenchymal Transition and Metastasis through Stabilizing HMGA1 mRNA in Gastric Cancer.
FTO Inhibits Epithelial Ovarian Cancer Progression by Destabilising SNAI1 mRNA through IGF2BP2.
Downregulation of TUSC3 promotes EMT and hepatocellular carcinoma progression through LIPC/AKT axis.
CAMK2N1 has a cancer-suppressive function in colorectal carcinoma via effects on the Wnt/β-catenin pathway.
Radix Glycyrrhizae Preparata Induces Cell Cycle Arrest and Induced Caspase-Dependent Apoptosis in Glioblastoma Multiforme.
Knockdown of TTC9 inhibits the proliferation, migration and invasion, but induces the apoptosis of lung adenocarcinoma cells.
Acyl-CoA thioesterase 9 promotes tumour growth and metastasis through reprogramming of fatty acid metabolism in hepatocellular carcinoma.
Targeting epiregulin in the treatment-damaged tumor microenvironment restrains therapeutic resistance.
Engineered biomimetic nanoreactor for synergistic photodynamic-chemotherapy against hypoxic tumor.
Biomimetic cell membrane-coated glucose/oxygen-exhausting nanoreactor for remodeling tumor microenvironment in targeted hypoxic tumor therapy.
Legumain affects the PI3K/AKT tumor progression pathway in retinoblastoma.
MYPT1 inhibits the metastasis of renal clear cell carcinoma via the MAPK8/N-cadherin pathway.
CHRNB2 represses pancreatic cancer migration and invasion via inhibiting β-catenin pathway.
SIRT2 promotes the viability, invasion and metastasis of osteosarcoma cells by inhibiting the degradation of Snail.
CBP-HSF2 structural and functional interplay in Rubinstein-Taybi neurodevelopmental disorder.
MiR-30e-3p inhibits gastric cancer development by negatively regulating THO complex 2 and PI3K/AKT/mTOR signaling.
Sertoli cells require TDP-43 to support spermatogenesis†.
NAP1L5 targeting combined with MYH9 Inhibit HCC progression through PI3K/AKT/mTOR signaling pathway.
KIF17 maintains the epithelial phenotype of breast cancer cells and curbs tumour metastasis.
The inhibition of centromere protein K causes anticancer effects in breast carcinoma via effects on the FAK/PI3K/AKT/mTOR pathway.
Kinesin family member 23, regulated by FOXM1, promotes triple negative breast cancer progression via activating Wnt/β-catenin pathway.
Forkhead Box q1 promotes invasion and metastasis in colorectal cancer by activating the epidermal growth factor receptor pathway.
FAM126A interacted with ENO1 mediates proliferation and metastasis in pancreatic cancer via PI3K/AKT signaling pathway.
FAT10 promotes chemotherapeutic resistance in pancreatic cancer by inducing epithelial-mesenchymal transition via stabilization of FOXM1 expression.
[P4HA2 promotes occurrence and progression of liver cancer by regulating the PI3K/Akt/mTOR signaling pathway].
Arylquin 1 (Potent Par-4 Secretagogue) Inhibits Tumor Progression and Induces Apoptosis in Colon Cancer Cells.
TMCO1 expression promotes cell proliferation and induces epithelial-mesenchymal transformation in human gliomas.
CXCL13 as a Novel Immune Checkpoint for Regulatory B Cells and Its Role in Tumor Metastasis.
Stanniocalcin2 inhibits the epithelial-mesenchymal transition and invasion of trophoblasts via activation of autophagy under high-glucose conditions.
Downregulated RRS1 inhibits invasion and metastasis of BT549 through RPL11‑c‑Myc‑SNAIL axis.
LACTB suppresses carcinogenesis in lung cancer and regulates the EMT pathway.
In situ injectable hydrogel-loaded drugs induce anti-tumor immune responses in melanoma immunochemotherapy.
LINC00244 suppresses cell growth and metastasis in hepatocellular carcinoma by downregulating programmed cell death ligand 1.
Inhibition of translocator protein 18 kDa suppressed the progression of glioma via the ELAV-like RNA-binding protein 1/MAPK-activated protein kinase 3 axis.
Transthyretin deposition alters cardiomyocyte sarcomeric architecture, calcium transients, and contractile force.
The cancer/testis antigen HORMAD1 mediates epithelial-mesenchymal transition to promote tumor growth and metastasis by activating the Wnt/β-catenin signaling pathway in lung cancer.
Ubiquitin conjugating enzyme E2 C (UBE2C) may play a dual role involved in the progression of thyroid carcinoma.
The miR-345-3p/PPP2CA signaling axis promotes proliferation and invasion of breast cancer cells.
Engineering of thick human functional myocardium via static stretching and electrical stimulation.
lncRNA SNHG26 promoted the growth, metastasis, and cisplatin resistance of tongue squamous cell carcinoma through PGK1/Akt/mTOR signal pathway.
Restraint of chaperonin containing T-complex protein-1 subunit 3 has antitumor roles in non-small cell lung cancer via affection of YAP1.
Pan-cancer analysis, cell and animal experiments revealing TEAD4 as a tumor promoter in ccRCC.
Deduction of CDC42EP3 suppress development and progression of osteosarcoma.
Identification of HMGCR as the anticancer target of physapubenolide against melanoma cells by in silico target prediction.
Osthole inhibits the migration and invasion of highly metastatic breast cancer cells by suppressing ITGα3/ITGβ5 signaling.
Circular RNA circ_0001459 accelerates hepatocellular carcinoma progression via the miR-6165/IGF1R axis.
A neutrophil-mediated carrier regulates tumor stemness by inhibiting autophagy to prevent postoperative triple-negative breast cancer recurrence and metastasis.
Circ_0005231 promotes the progression of esophageal squamous cell carcinoma via sponging miR-383-5p and regulating KIAA0101.
CXCR4 inhibition attenuates calcium oxalate crystal deposition-induced renal fibrosis.
Stress-induced epinephrine promotes epithelial-to-mesenchymal transition and stemness of CRC through the CEBPB/TRIM2/P53 axis.
Pharmacological Inhibition of Endogenous Hydrogen Sulfide Attenuates Breast Cancer Progression.
Phenazine derivatives attenuate the stemness of breast cancer cells through triggering ferroptosis.
The ETS1-LINC00278 negative feedback loop plays a role in COL4A1/COL4A2 regulation in laryngeal squamous cell carcinoma.
Methylation-mediated expression of SPARC is correlated with tumor progression and poor prognosis of breast cancer.
Overexpression of ERCC6L correlates with poor prognosis and confers malignant phenotypes of lung adenocarcinoma.
Inhibition of PDK1 enhances radiosensitivity and reverses epithelial-mesenchymal transition in nasopharyngeal carcinoma.
Hypoxia-inducible factor-2α promotes EMT in esophageal squamous cell carcinoma through the Notch pathway.
Autophagy deficiency promotes lung metastasis of prostate cancer via stabilization of TWIST1.
LncRNA HOTTIP PROMOTES OVARIAN CANCER CELL INVASION AND METASTASIS BY STABILIZING HIF-1α IN THE ANOXIC CELLULAR MICROENVIRONMENT.
Discovery of Novel Phosphoinositide-3-Kinase α Inhibitors with High Selectivity, Excellent Bioavailability, and Long-Acting Efficacy for Gastric Cancer.
Ginsenoside Rh4 Suppresses Metastasis of Esophageal Cancer and Expression of c-Myc via Targeting the Wnt/β-Catenin Signaling Pathway.
CircGPR137B/miR-4739/FTO feedback loop suppresses tumorigenesis and metastasis of hepatocellular carcinoma.
Hyaluronic Acid Modified Nanostructured Lipid Carrier for Targeting Delivery of Kaempferol to NSCLC: Preparation, Optimization, Characterization, and Performance Evaluation In Vitro.
The Chinese medicine Fufang Zhenzhu Tiaozhi capsule protects against atherosclerosis by suppressing EndMT via modulating Akt1/β-catenin signaling pathway.
RBM47 inhibits hepatocellular carcinoma progression by targeting UPF1 as a DNA/RNA regulator.
Deubiquitinase USP13 promotes the epithelial-mesenchymal transition and metastasis in gastric cancer by maintaining Snail protein.
MICAL1 inhibits colorectal cancer cell migration and proliferation by regulating the EGR1/β-catenin signaling pathway.
Dihydroartemisinin represses oral squamous cell carcinoma progression through downregulating mitochondrial calcium uniporter.
circUSP34 accelerates osteosarcoma malignant progression by sponging miR-16-5p.
YTHDF3 facilitates triple-negative breast cancer progression and metastasis by stabilizing ZEB1 mRNA in an m(6)A-dependent manner.
G-protein Coupled Receptor 34 Promotes Gliomagenesis by Inducing Proliferation and Malignant Phenotype via TGF-Beta/Smad Signaling Pathway.
miR-498 Targets UBE2T to Inhibit the Proliferation of Malignant Melanoma Cells.
Astragalus membranaceus (Huangqi) and Rhizoma curcumae (Ezhu) decoction suppresses colorectal cancer via downregulation of Wnt5/β-Catenin signal.
STK25 enhances hepatocellular carcinoma progression through the STRN/AMPK/ACC1 pathway.
Circ_0078607 inhibits the progression of ovarian cancer via regulating the miR-32-5p/SIK1 network.
HERC3 regulates epithelial-mesenchymal transition by directly ubiquitination degradation EIF5A2 and inhibits metastasis of colorectal cancer.
Identification of Pyruvate Carboxylase as the Cellular Target of Natural Bibenzyls with Potent Anticancer Activity against Hepatocellular Carcinoma via Metabolic Reprogramming.
ZC3H15 promotes glioblastoma progression through regulating EGFR stability.
CACNA1B facilitates breast cancer cell growth and migration by regulating cyclin D1 and EMT: the implication of CACNA1B in breast cancer.
FGD3 binds with HSF4 to suppress p65 expression and inhibit pancreatic cancer progression.
The keratin 17/YAP/IL6 axis contributes to E-cadherin loss and aggressiveness of diffuse gastric cancer.
MiR-4521 plays a tumor repressive role in growth and metastasis of hepatocarcinoma cells by suppressing phosphorylation of FAK/AKT pathway via targeting FAM129A.
Dihydrotestosterone through blockade of TGF-β/Smad signaling mediates the anti-fibrosis effect under hypoxia in canine Sertoli cells.
Cancer-associated fibroblasts promote tumor progression by lncRNA-mediated RUNX2/GDF10 signaling in oral squamous cell carcinoma.
Ubiquitin-specific peptidase 2 inhibits epithelial-mesenchymal transition in clear cell renal cell carcinoma metastasis by downregulating the NF-κB pathway.
Foxhead box D1 promotes the partial epithelial-to-mesenchymal transition of laryngeal squamous cell carcinoma cells via transcriptionally activating the expression of zinc finger protein 532.
Hyperglycemia induces miR-26-5p down-regulation to overexpress PFKFB3 and accelerate epithelial-mesenchymal transition in gastric cancer.
MiR-187 regulates the proliferation, migration and invasion of human trophoblast cells by repressing BCL6-mediated activation of PI3K/AKT signaling.
HDAC9 Contributes to Serous Ovarian Cancer Progression through Regulating Epithelial-Mesenchymal Transition.
Norepinephrine promotes glioma cell migration through up-regulating the expression of Twist1.
Numb-PRRL promotes TGF-β1- and EGF-induced epithelial-to-mesenchymal transition in pancreatic cancer.
YTHDF1 promotes breast cancer progression by facilitating FOXM1 translation in an m6A-dependent manner.
ZHX2 inhibits thyroid cancer metastasis through transcriptional inhibition of S100A14.
Ginsenoside Rh4 Suppressed Metastasis of Lung Adenocarcinoma via Inhibiting JAK2/STAT3 Signaling.
FERMT1 contributes to the migration and invasion of nasopharyngeal carcinoma through epithelial-mesenchymal transition and cell cycle arrest.
CircCERS6 Suppresses the Development of Epithelial Ovarian Cancer Through Mediating miR-630/RASSF8.
Study on the biological mechanism of urolithin a on nasopharyngeal carcinoma in vitro.
Relaxin inhibits renal fibrosis and the epithelial-to-mesenchymal transition via the Wnt/β-catenin signaling pathway.
Cystathionine γ-lyase mediates cell proliferation, migration, and invasion of nasopharyngeal carcinoma.
IRF2-ferroptosis related gene is associated with prognosis and EMT in gliomas.
ALG2 inhibits the epithelial-to-mesenchymal transition and stemness of ovarian granulosa cells through the Wnt/β-catenin signaling pathway in polycystic ovary syndrome.
Transcription factor SP1 and oncoprotein PPP1R13L regulate nicotine-induced epithelial-mesenchymal transition in lung adenocarcinoma via a feedback loop.
Artemisitene suppresses rheumatoid arthritis progression via modulating METTL3-mediated N6-methyladenosine modification of ICAM2 mRNA in fibroblast-like synoviocytes.
Silencing of lncRNA SNHG17 inhibits the tumorigenesis of epithelial ovarian cancer through regulation of miR-485-5p/AKT1 axis.
Exosome-transmitted S100A4 induces immunosuppression and non-small cell lung cancer development by activating STAT3.
lncRNA ZNRD1-AS1 promotes malignant lung cell proliferation, migration, and angiogenesis via the miR-942/TNS1 axis and is positively regulated by the m(6)A reader YTHDC2.
FAT4 activation inhibits epithelial-mesenchymal transition (EMT) by promoting autophagy in H2228/Cer cells.
Krüppel-like Factor 13 Promotes HCC Progression by Transcriptional Regulation of HMGCS1-mediated Cholesterol Synthesis.
Increased expression of miR-194-5p through the circPVRL3/miR-194-5p/SOCS2 axis promotes proliferation and metastasis in pancreatic ductal adenocarcinoma by activating the PI3K/AKT signaling pathway.
A multifunctional black phosphorus-based adhesive patch intrinsically induces partial EMT for effective burn wound healing.
Extracellular matrix modulating enzyme functionalized biomimetic Au nanoplatform-mediated enhanced tumor penetration and synergistic antitumor therapy for pancreatic cancer.
Novel shikonin derivatives suppress cell proliferation, migration and induce apoptosis in human triple-negative breast cancer cells via regulating PDK1/PDHC axis.
Identification of endocrine-disrupting chemicals targeting the genes and pathways of genital anomalies in males.
YAP1-TEAD1 mediates the perineural invasion of prostate cancer cells induced by cancer-associated fibroblasts.
Suppression of rhomboid domain-containing 1 produces anticancer effects in pancreatic adenocarcinoma through affection of the AKT/GSK-3β/β-catenin pathway.
XIST sponges miR-320d to promote chordoma progression by regulating ARF6.
Downstream Neighbor of Son Overexpression is Associated With Breast Cancer Progression and a Poor Prognosis.
Agmatinase facilitates the tumorigenesis of pancreatic adenocarcinoma through the TGFβ/Smad pathway.
Nav1.6 promotes the progression of human follicular thyroid carcinoma cells via JAK-STAT signaling pathway.
Nascent Proteome and Glycoproteome Reveal the Inhibition Role of ALG1 in Hepatocellular Carcinoma Cell Migration.
HIF-1α induced NID1 expression promotes pulmonary metastases via the PI3K-AKT pathway in salivary gland adenoid cystic carcinoma.
PEBP4 Directs the Malignant Behavior of Hepatocellular Carcinoma Cells via Regulating mTORC1 and mTORC2.
Long noncoding RNA CERS6-AS1 modulates glucose metabolism and tumor progression in hepatocellular carcinoma by promoting the MDM2/p53 signaling pathway.
Hypermethylation of PRKCZ Regulated by E6 Inhibits Invasion and EMT via Cdc42 in HPV-Related Head and Neck Squamous Cell Carcinoma.
Discovery of a Novel Small-Molecule Inhibitor Disrupting TRBP-Dicer Interaction against Hepatocellular Carcinoma via the Modulation of microRNA Biogenesis.
Exosomal miR-155-5p derived from glioma stem-like cells promotes mesenchymal transition via targeting ACOT12.
FAM107A Inactivation Associated with Promoter Methylation Affects Prostate Cancer Progression through the FAK/PI3K/AKT Pathway.
miR-596-3p suppresses brain metastasis of non-small cell lung cancer by modulating YAP1 and IL-8.
PDCD10 promotes the aggressive behaviors of pituitary adenomas by up-regulating CXCR2 and activating downstream AKT/ERK signaling.
Jianpi Huayu decoction inhibits the epithelial-mesenchymal transition of hepatocellular carcinoma cells by suppressing exosomal miR-23a-3p/Smad signaling.
EML4-ALK G1202R mutation induces EMT and confers resistance to ceritinib in NSCLC cells via activation of STAT3/Slug signaling.
Interleukin-17A mediates tobacco smoke-induced lung cancer epithelial-mesenchymal transition through transcriptional regulation of ΔNp63α on miR-19.
Tumor-specific nitric oxide generator to amplify peroxynitrite based on highly penetrable nanoparticles for metastasis inhibition and enhanced cancer therapy.
Terpinen-4-ol inhibits the proliferation and mobility of pancreatic cancer cells by downregulating Rho-associated coiled-coil containing protein kinase 2.
Ginsenoside Rh4 Suppresses Metastasis of Gastric Cancer via SIX1-Dependent TGF-β/Smad2/3 Signaling Pathway.
TIM-1 promotes proliferation and metastasis, and inhibits apoptosis, in cervical cancer through the PI3K/AKT/p53 pathway.
Brusatol inhibits the growth of renal cell carcinoma by regulating the PTEN/PI3K/AKT pathway.
Overexpression of GATA5 Inhibits Prostate Cancer Progression by Regulating PLAGL2 via the FAK/PI3K/AKT Pathway.
HGF/c-Met pathway facilitates the perineural invasion of pancreatic cancer by activating the mTOR/NGF axis.
Epigenetic Deregulation of Protein Tyrosine Kinase 6 Promotes Carcinogenesis of Oral Squamous Cell Carcinoma.
METTL3-mediated m6A modification of STEAP2 mRNA inhibits papillary thyroid cancer progress by blocking the Hedgehog signaling pathway and epithelial-to-mesenchymal transition.
Hexachlorophene, a selective SHP2 inhibitor, suppresses proliferation and metastasis of KRAS-mutant NSCLC cells by inhibiting RAS/MEK/ERK and PI3K/AKT signaling pathways.
Silencing of Nudix type 5 represses proliferation and invasion and enhances chemosensitivity of gastric carcinoma cells by affecting the AKT/GSK-3β/β-catenin pathway.
SMAD3 and FTO are involved in miR-5581-3p-mediated inhibition of cell migration and proliferation in bladder cancer.
Metabolites and Biomarker Compounds of Neurodegenerative Diseases in Cerebrospinal Fluid.
m6A Modification-Mediated DUXAP8 Regulation of Malignant Phenotype and Chemotherapy Resistance of Hepatocellular Carcinoma Through miR-584-5p/MAPK1/ERK Pathway Axis.
Resveratrol-Loaded TPGS-Resveratrol-Solid Lipid Nanoparticles for Multidrug-Resistant Therapy of Breast Cancer: In Vivo and In Vitro Study.
PRDM16 Inhibits Cell Proliferation and Migration via Epithelial-to-Mesenchymal Transition by Directly Targeting Pyruvate Carboxylase in Papillary Thyroid Cancer.
Circular RNA circSIPA1L1 Contributes to Osteosarcoma Progression Through the miR-411-5p/RAB9A Signaling Pathway.
MicroRNA-15a Carried by Mesenchymal Stem Cell-Derived Extracellular Vesicles Inhibits the Immune Evasion of Colorectal Cancer Cells by Regulating the KDM4B/HOXC4/PD-L1 Axis.
ENC1 Facilitates Colorectal Carcinoma Tumorigenesis and Metastasis via JAK2/STAT5/AKT Axis-Mediated Epithelial Mesenchymal Transition and Stemness.
Transcription Factors BARX1 and DLX4 Contribute to Progression of Clear Cell Renal Cell Carcinoma via Promoting Proliferation and Epithelial-Mesenchymal Transition.
Acyl-CoA Thioesterase 7 is Transcriptionally Activated by Krüppel-Like Factor 13 and Promotes the Progression of Hepatocellular Carcinoma.
Inositol Hexakisphosphate and Inositol Enhance the Inhibition of Colorectal Cancer Growth and Liver Metastasis by Capecitabine in a Mouse Model.
Qingjie Fuzheng Granule Inhibits EMT and Induces Autophagy in Colorectal Cancer via mTOR Signaling Pathways.
Network Pharmacology-Based Mechanistic Investigation of Jinshui Huanxian Formula Acting on Idiopathic Pulmonary Fibrosis.
ARHGEF10L Promotes Cervical Tumorigenesis via RhoA-Mediated Signaling.
lncRNA LINC01296 Promotes Oral Squamous Cell Carcinoma Development by Binding with SRSF1.
Therapeutic Potential of RTA 404 in Human Brain Malignant Glioma Cell Lines via Cell Cycle Arrest via p21/AKT Signaling.
BOP1 Used as a Novel Prognostic Marker and Correlated with Tumor Microenvironment in Pan-Cancer.
Cysteine-Rich Intestinal Protein 1 Served as an Epithelial Ovarian Cancer Marker via Promoting Wnt/β-Catenin-Mediated EMT and Tumour Metastasis.
Trefoil Factor 3 Inhibits Thyroid Cancer Cell Progression Related to IL-6/JAK/STAT3 Signaling Pathway.
YY1-modulated long non-coding RNA SNHG12 promotes gastric cancer metastasis by activating the miR-218-5p/YWHAZ axis.
ITGB1 enhances the Radioresistance of human Non-small Cell Lung Cancer Cells by modulating the DNA damage response and YAP1-induced Epithelial-mesenchymal Transition.
miR-34a-5p functions as a tumor suppressor in head and neck squamous cell cancer progression by targeting Flotillin-2.
Cyclovirobuxine inhibits the progression of clear cell renal cell carcinoma by suppressing the IGFBP3-AKT/STAT3/MAPK-Snail signalling pathway.
Downregulation of m(6)A Reader YTHDC2 Promotes the Proliferation and Migration of Malignant Lung Cells via CYLD/NF-κB Pathway.
Delivery of Rapamycin by Liposomes Synergistically Enhances the Chemotherapy Effect of 5-Fluorouracil on Colorectal Cancer.
TEAD4 as a Prognostic Marker Promotes Cell Migration and Invasion of Urinary Bladder Cancer via EMT.
LncRNA UCID Promotes Hepatocellular Carcinoma Metastasis via Stabilization of Snail.
A c-Met Inhibitor Suppresses Osteosarcoma Progression via the ERK1/2 Pathway in Human Osteosarcoma Cells.
XBP1s Acts as a Tumor Suppressor to Inhibit the EMT Process and Metastasis of Papillary Thyroid Cancer.
FUT7 Promotes the Epithelial-Mesenchymal Transition and Immune Infiltration in Bladder Urothelial Carcinoma.
LncRNA IGFL2-AS1 Promotes the Proliferation, Migration, and Invasion of Colon Cancer Cells and is Associated with Patient Prognosis.
Plakophilin-2 Promotes Lung Adenocarcinoma Development via Enhancing Focal Adhesion and Epithelial-Mesenchymal Transition.
ARRB1 Drives Gallbladder Cancer Progression by Facilitating TAK1/MAPK Signaling Activation.
GTW inhibits the Epithelial to Mesenchymal Transition of Epithelial Ovarian Cancer via ILK/AKT/GSK3β/Slug Signalling Pathway.
JMJD8 Promotes Malignant Progression of Lung Cancer by Maintaining EGFR Stability and EGFR/PI3K/AKT Pathway Activation.
Deltex3 inhibits Epithelial Mesenchymal Transition in Papillary Thyroid Carcinoma via promoting ubiquitination of XRCC5 to regulate the AKT signal pathway.
Keratin 80 regulated by miR-206/ETS1 promotes tumor progression via the MEK/ERK pathway in ovarian cancer.
SNX-2112 Induces Apoptosis and Inhibits Proliferation, Invasion, and Migration of Non-Small Cell Lung Cancer by Downregulating Epithelial-Mesenchymal Transition via the Wnt/β-Catenin Signaling Pathway.
Elevated HNF1A expression promotes radiation-resistance via driving PI3K/AKT signaling pathway in esophageal squamous cell carcinoma cells.
Demethylzelasteral inhibits proliferation and EMT via repressing Wnt/β-catenin signaling in esophageal squamous cell carcinoma.
Dextran Sulfate Effects EMT of Human Gastric Cancer Cells by Reducing HIF-1α/ TGF-β.
Induction of Mitosis Delay and Apoptosis by CDDO-TFEA in Glioblastoma Multiforme.
Inhibitory Effect of Dihydroartemisinin on the Proliferation and Migration of Melanoma Cells and Experimental Lung Metastasis From Melanoma in Mice.
Association of Pericyte Loss With Microthrombosis After Subarachnoid Hemorrhage in ApoE-Deficient Mice.
CXCL5 Downregulation in Villous Tissue Is Correlated With Recurrent Spontaneous Abortion.
Decreased USP2a Expression Inhibits Trophoblast Invasion and Associates With Recurrent Miscarriage.
Oxymatrine Synergistically Enhances Doxorubicin Anticancer Effects in Colorectal Cancer.
Autophagic Inhibition of Caveolin-1 by Compound Phyllanthus urinaria L. Activates Ubiquitination and Proteasome Degradation of β-catenin to Suppress Metastasis of Hepatitis B-Associated Hepatocellular Carcinoma.
PLAU Promotes Cell Proliferation and Epithelial-Mesenchymal Transition in Head and Neck Squamous Cell Carcinoma.
Molecular Subtypes Based on the Stemness Index Predict Prognosis in Glioma Patients.
Extracellular vesicles derived from M1 macrophages deliver miR-146a-5p and miR-146b-5p to suppress trophoblast migration and invasion by targeting TRAF6 in recurrent spontaneous abortion.
Epigenetically silenced linc00261 contributes to the metastasis of hepatocellular carcinoma via inducing the deficiency of FOXA2 transcription.
PKM2 Is the Target of a Multi-Herb-Combined Decoction During the Inhibition of Gastric Cancer Progression.
Long Non-Coding RNA CCAT2 Activates RAB14 and Acts as an Oncogene in Colorectal Cancer.
Honokiol Suppresses Perineural Invasion of Pancreatic Cancer by Inhibiting SMAD2/3 Signaling.
Siglec-15 Promotes Tumor Progression in Osteosarcoma via DUSP1/MAPK Pathway.
YBX1 Enhances Metastasis and Stemness by Transcriptionally Regulating MUC1 in Lung Adenocarcinoma.
Photobiomodulation With Blue Laser Inhibits Bladder Cancer Progression.
TRIM50 Suppresses Pancreatic Cancer Progression and Reverses the Epithelial-Mesenchymal Transition via Facilitating the Ubiquitous Degradation of Snail1.
MiR-1236-3p Inhibits the Proliferation, Invasion, and Migration of Colon Cancer Cells and Hinders Epithelial-Mesenchymal Transition by Targeting DCLK3.
PGK1 Is a Key Target for Anti-Glycolytic Therapy of Ovarian Cancer: Based on the Comprehensive Analysis of Glycolysis-Related Genes.
miR-1258 Attenuates Tumorigenesis Through Targeting E2F1 to Inhibit PCNA and MMP2 Transcription in Glioblastoma.
N2E4, a Monoclonal Antibody Targeting Neuropilin-2, Inhibits Tumor Growth and Metastasis in Pancreatic Ductal Adenocarcinoma via Suppressing FAK/Erk/HIF-1α Signaling.
The lncRNA ADAMTS9-AS2 Regulates RPL22 to Modulate TNBC Progression via Controlling the TGF-β Signaling Pathway.
Long Non-Coding RNA LINC00467 Correlates to Poor Prognosis and Aggressiveness of Breast Cancer.
Derivation and Validation of a Prognostic Model for Cancer Dependency Genes Based on CRISPR-Cas9 in Gastric Adenocarcinoma.
miR-139-5p Loss-Mediated WTAP Activation Contributes to Hepatocellular Carcinoma Progression by Promoting the Epithelial to Mesenchymal Transition.
Association of Preoperative NANOG-Positive Circulating Tumor Cell Levels With Recurrence of Hepatocellular Carcinoma.
Epigallocatechin-3-gallate inhibits proliferation and triggers apoptosis in colon cancer via the hedgehog/phosphoinositide 3-kinase pathways.
Aiduqing formula suppresses breast cancer metastasis via inhibiting CXCL1-mediated autophagy.
Homoharringtonine inhibits the progression of hepatocellular carcinoma by suppressing the PI3K/AKT/GSK3β/Slug signaling pathway.
Polystyrene microplastics induce blood-testis barrier disruption regulated by the MAPK-Nrf2 signaling pathway in rats.
Demethylzeylasteral inhibits proliferation, migration, and invasion through FBXW7/c-Myc axis in gastric cancer.
Investigation of the Epithelial to Mesenchymal Transition (EMT) Process in Equine Papillomavirus-2 (EcPV-2)-Positive Penile Squamous Cell Carcinomas.
Identification of abnormally high expression of POGZ as a new biomarker associated with a poor prognosis in osteosarcoma.
PHLDA3 exerts an antitumor function in prostate cancer by down-regulating Wnt/β-catenin pathway via inhibition of Akt.
KLK8 promotes the proliferation and metastasis of colorectal cancer via the activation of EMT associated with PAR1.
MiR-613 inhibits the proliferation, migration, and invasion of papillary thyroid carcinoma cells by directly targeting TAGLN2.
TNFSF9 promotes metastasis of pancreatic cancer through Wnt/Snail signaling and M2 polarization of macrophages.
Oleanolic acid inhibits the migration and invasion of hepatocellular carcinoma cells by promoting microRNA-122 expression.
MIER3 induces epithelial-mesenchymal transition and promotes breast cancer cell aggressiveness via forming a co-repressor complex with HDAC1/HDAC2/Snail.
Upregulation of microfibrillar-associated protein 2 is closely associated with tumor angiogenesis and poor prognosis in hepatocellular carcinoma.
Dihydroartemisinin suppresses proliferation, migration, the Wnt/β-catenin pathway and EMT via TNKS in gastric cancer.
PFP@PLGA/Cu(12)Sb(4)S(13)-mediated PTT ablates hepatocellular carcinoma by inhibiting the RAS/MAPK/MT-CO1 signaling pathway.
AnnexinA7 promotes epithelial-mesenchymal transition by interacting with Sorcin and contributes to aggressiveness in hepatocellular carcinoma.
UM-6 induces autophagy and apoptosis via the Hippo-YAP signaling pathway in cervical cancer.
ZEB1 represses biogenesis of circ-DOCK5 to facilitate metastasis in esophageal squamous cell carcinoma via a positive feedback loop with TGF-β.
Circular RNA circUBE2J2 acts as the sponge of microRNA-370-5P to suppress hepatocellular carcinoma progression.
NOV/CCN3 Promotes Cell Migration and Invasion in Intrahepatic Cholangiocarcinoma via miR-92a-3p.
RTA404, an Activator of Nrf2, Activates the Checkpoint Kinases and Induces Apoptosis through Intrinsic Apoptotic Pathway in Malignant Glioma.
Upregulation of CPNE7 in mesenchymal stromal cells promotes oral squamous cell carcinoma metastasis through the NF-κB pathway.
GP73-mediated secretion of AFP and GP73 promotes proliferation and metastasis of hepatocellular carcinoma cells.
P-element Induced WImpy protein-like RNA-mediated gene silencing 2 regulates tumor cell progression, apoptosis, and metastasis in oral squamous cell carcinoma.
Abnormally elevated ubiquilin‑1 expression in breast cancer regulates metastasis and stemness via AKT signaling.
Silencing ACTG1 Expression Induces Prostate Cancer Epithelial Mesenchymal Transition Through MAPK/ERK Signaling Pathway.
The anti-neoplastic activities of aloperine in HeLa cervical cancer cells are associated with inhibition of the IL-6-JAK1-STAT3 feedback loop.
Effects of Cynaroside on Cell Proliferation, Apoptosis, Migration and Invasion though the MET/AKT/mTOR Axis in Gastric Cancer.
WITHDRAWN: Transcriptional regulation of miR-483-3p mediated by IL-6/STAT3 axis promoted epithelial-mesenchymal transition and tumor stemness in glioma.
HMMR is a downstream target of FOXM1 in enhancing proliferation and partial epithelial-to-mesenchymal transition of bladder cancer cells.
Drug-containing serum of rhubarb-astragalus capsule inhibits the epithelial-mesenchymal transformation of HK-2 by downregulating TGF-β1/p38MAPK/Smad2/3 pathway.
Single-Cell Analyses Reveal Mechanisms of Cancer Stem Cell Maintenance and Epithelial-Mesenchymal Transition in Recurrent Bladder Cancer.
Deletion of miR-15a inhibited glioma development via targeting Smad7 and inhibiting EMT pathway.
Methylation gene KCNC1 is associated with overall survival in patients with seminoma.
The clinical significance, prognostic value and biological role of lncRNA LINC01793 in oral squamous cell carcinoma.
Ginsenoside CK Inhibits Hypoxia-Induced Epithelial-Mesenchymal Transformation through the HIF-1α/NF-κB Feedback Pathway in Hepatocellular Carcinoma.
Identification of collagen genes related to immune infiltration and epithelial-mesenchymal transition in glioma.
Knockout RAGE alleviates cardiac fibrosis through repressing endothelial-to-mesenchymal transition (EndMT) mediated by autophagy.
Hsa_circ_0076305 induces migration-proliferation dichotomy in gastric cancer.
Aptamer-SH2 superbinder-based targeted therapy for pancreatic ductal adenocarcinoma.
Structural basis for human TRPC5 channel inhibition by two distinct inhibitors.
Sesquiterpene Lactone Deoxyelephantopin Isolated from Elephantopus scaber and Its Derivative DETD-35 Suppress BRAF(V600E) Mutant Melanoma Lung Metastasis in Mice.
DCBLD2 Mediates Epithelial-Mesenchymal Transition-Induced Metastasis by Cisplatin in Lung Adenocarcinoma.
PEG-GO@XN nanocomposite suppresses breast cancer metastasis via inhibition of mitochondrial oxidative phosphorylation and blockade of epithelial-to-mesenchymal transition.
Upregulation of bromodomain PHD finger transcription factor in ovarian cancer and its critical role for cancer cell proliferation and survival.
Suberoylanilide Hydroxamic Acid (SAHA) Reduces Fibrosis Markers and Deactivates Human Stellate Cells via the Epithelial-Mesenchymal Transition (EMT).
MicroRNA‑485‑5p suppresses the progression of esophageal squamous cell carcinoma by targeting flotillin‑1 and inhibits the epithelial‑mesenchymal transition.
Fructose-1,6-bisphosphatase aggravates oxidative stress-induced apoptosis in asthma by suppressing the Nrf2 pathway.
SEC61G is upregulated and required for tumor progression in human kidney cancer.
MicroRNA-133a-3p suppresses malignant behavior of non-small cell lung cancer cells by negatively regulating ERBB2.
LEM domain containing 1 promotes thyroid cancer cell proliferation and migration by activating the Wnt/β-catenin signaling pathway and epithelial-mesenchymal transition.
Ketoplatin in triple-negative breast cancer cells MDA-MB-231: High efficacy and low toxicity, and positive impact on inflammatory microenvironment.
LncRNA MONC suppresses the malignant phenotype of Endometrial Cancer Stem Cells and Endometrial Carcinoma Cells by regulating the MiR-636/GLCE axis.
CD74 promotes perineural invasion of cancer cells and mediates neuroplasticity via the AKT/EGR-1/GDNF axis in pancreatic ductal adenocarcinoma.
Identification of a Novel TAR RNA-Binding Protein 2 Modulator with Potential Therapeutic Activity against Hepatocellular Carcinoma.
YB1 regulates miR-205/200b-ZEB1 axis by inhibiting microRNA maturation in hepatocellular carcinoma.
Regulatory effect of microRNA-223-3p on breast cancer cell processes via the Hippo/Yap signaling pathway.
The oncogenic role of the cerebral endothelial cell adhesion molecule (CERCAM) in bladder cancer cells in vitro and in vivo.
A novel chemical inhibitor suppresses breast cancer cell growth and metastasis through inhibiting HPIP oncoprotein.
TGF-β1-mediated exosomal lnc-MMP2-2 increases blood-brain barrier permeability via the miRNA-1207-5p/EPB41L5 axis to promote non-small cell lung cancer brain metastasis.
METTL7B is a novel prognostic biomarker of lower-grade glioma based on pan-cancer analysis.
Circular RNA circ_001422 promotes the progression and metastasis of osteosarcoma via the miR-195-5p/FGF2/PI3K/Akt axis.
LncRNA PCGEM1 induces proliferation and migration in non-small cell lung cancer cells through modulating the miR-590-3p/SOX11 axis.
Mitochondrial creatine kinase 1 in non-small cell lung cancer progression and hypoxia adaptation.
Fangchinoline exerts antitumour activity by suppressing the EGFR‑PI3K/AKT signalling pathway in colon adenocarcinoma.
MSH6 Aggravates the Hypoxic Microenvironment via Regulating HIF1A to Promote the Metastasis of Glioblastoma Multiforme.
Triptolidenol, isolated from Tripterygium wilfordii, disrupted NF-κB/COX-2 pathway by targeting ATP-binding sites of IKKβ in clear cell renal cell carcinoma.
Lidocaine inhibits the metastatic potential of ovarian cancer by blocking Na(V) 1.5-mediated EMT and FAK/Paxillin signaling pathway.
Glycosyltransferase POMGNT1 deficiency strengthens N-cadherin-mediated cell-cell adhesion.
Obacunone Attenuates Liver Fibrosis with Enhancing Anti-Oxidant Effects of GPx-4 and Inhibition of EMT.
Polystyrene microplastics induced male reproductive toxicity in mice.
Histone methyltransferase SUV39H2 regulates LSD1-dependent CDH1 expression and promotes epithelial mesenchymal transition of osteosarcoma.
Overexpression of NCAPG inhibits cardia adenocarcinoma apoptosis and promotes epithelial-mesenchymal transition through the Wnt/β-catenin signaling pathway.
Circ_0001438 participates in the pathogenesis of preeclampsia via the circ_0001438/miR-942/NLRP3 regulatory network.
A "dual-guide" bioinspired drug delivery strategy of a macrophage-based carrier against postoperative triple-negative breast cancer recurrence.
PGRN(-/-) TAMs-derived exosomes inhibit breast cancer cell invasion and migration and its mechanism exploration.
Prostacyclin facilitates vascular smooth muscle cell phenotypic transformation via activating TP receptors when IP receptors are deficient.
USP1-WDR48 deubiquitinase complex enhances TGF-β induced epithelial-mesenchymal transition of TNBC cells via stabilizing TAK1.
Cancer-associated fibroblast-derived SDF-1 induces epithelial-mesenchymal transition of lung adenocarcinoma via CXCR4/β-catenin/PPARδ signalling.
DUOX2 promotes the progression of colorectal cancer cells by regulating the AKT pathway and interacting with RPL3.
Long non-coding RNA AC122108.1 promotes lung adenocarcinoma brain metastasis and progression through the Wnt/β-catenin pathway by directly binding to aldolase A.
PDGF-BB promotes vascular smooth muscle cell migration by enhancing Pim-1 expression via inhibiting miR-214.
IFIT1 modulates the proliferation, migration and invasion of pancreatic cancer cells via Wnt/β-catenin signaling.
Exosomal ANXA2 derived from ovarian cancer cells regulates epithelial-mesenchymal plasticity of human peritoneal mesothelial cells.
Knockdown of METTL14 suppresses the malignant progression of non-small cell lung cancer by reducing Twist expression.
TRIP4 transcriptionally activates DDIT4 and subsequent mTOR signaling to promote glioma progression.
Long non-coding RNA VCAN-AS1 promotes the malignant behaviors of breast cancer by regulating the miR-106a-5p-mediated STAT3/HIF-1α pathway.
Knockdown of carbohydrate sulfotransferase 12 decreases the proliferation and mobility of glioblastoma cells via the WNT/β-catenin pathway.
SETD8 induces stemness and epithelial-mesenchymal transition of pancreatic cancer cells by regulating ROR1 expression.
Long non-coding RNA CRNDE exacerbates NPC advancement mediated by the miR-545-5p/CCND2 axis.
Cancer-Erythrocyte Hybrid Membrane-Camouflaged Magnetic Nanoparticles with Enhanced Photothermal-Immunotherapy for Ovarian Cancer.
TMED3 exerts a protumor function in non-small cell lung cancer by enhancing the Wnt/β-catenin pathway via regulation of AKT.
ATF3 inhibits arsenic-induced malignant transformation of human bronchial epithelial cells by attenuating inflammation.
TMEM229A suppresses non‑small cell lung cancer progression via inactivating the ERK pathway.
Chromium (VI) promotes EMT by regulating FLNA in BLCA.
W436, a novel SMART derivative, exhibits anti-hepatocarcinoma activity by inducing apoptosis and G2/M cell cycle arrest in vitro and in vivo and induces protective autophagy.
Deubiquitinase USP39 and E3 ligase TRIM26 balance the level of ZEB1 ubiquitination and thereby determine the progression of hepatocellular carcinoma.
miR‑200b upregulation promotes migration of BEAS‑2B cells following long‑term exposure to cigarette smoke by targeting ETS1.
Tripterygium glycoside suppresses epithelial‑to‑mesenchymal transition of diabetic kidney disease podocytes by targeting autophagy through the mTOR/Twist1 pathway.
Melatonin inhibits gallbladder cancer cell migration and invasion via ERK-mediated induction of epithelial-to-mesenchymal transition.
Depletion of CIP2A inhibits the proliferation, migration, invasion and epithelial-mesenchymal transition of glioma cells.
Caveolin-1 facilitates cell migration by upregulating nuclear receptor 4A2/retinoid X receptor α-mediated β-galactoside α2,6-sialyltransferase I expression in human hepatocarcinoma cells.
Yak milk-derived exosomes alleviate lipopolysaccharide-induced intestinal inflammation by inhibiting PI3K/AKT/C3 pathway activation.
Association of CASC18/miR-20a-3p/TGFB2 ceRNA axis with occult lymph node metastasis in tongue squamous cell carcinoma.
Cyanidin-3-glucoside suppresses the progression of lung adenocarcinoma by downregulating TP53I3 and inhibiting PI3K/AKT/mTOR pathway.
ICAM1 initiates CTC cluster formation and trans-endothelial migration in lung metastasis of breast cancer.
CRSP8 promotes thyroid cancer progression by antagonizing IKKα-induced cell differentiation.
The miR-136-5p/ROCK1 axis suppresses invasion and migration, and enhances cisplatin sensitivity in head and neck cancer cells.
SPT6 recruits SND1 to co-activate human telomerase reverse transcriptase to promote colon cancer progression.
H. sinensis mycelium inhibits epithelial-mesenchymal transition by inactivating the midkine pathway in pulmonary fibrosis.
Loss of CPAP causes sustained EGFR signaling and epithelial-mesenchymal transition in oral cancer.
Histone Deacetylases Inhibit the Snail2-Mediated EMT During Metastasis of Hepatocellular Carcinoma Cells.
Hypoxia-Inducible Ubiquitin Specific Peptidase 13 Contributes to Tumor Growth and Metastasis via Enhancing the Toll-Like Receptor 4/Myeloid Differentiation Primary Response Gene 88/Nuclear Factor-κB Pathway in Hepatocellular Carcinoma.
miR-193a-3p Mediates Placenta Accreta Spectrum Development by Targeting EFNB2 via Epithelial-Mesenchymal Transition Pathway Under Decidua Defect Conditions.
miR-124-3p Suppresses the Invasiveness and Metastasis of Hepatocarcinoma Cells via Targeting CRKL.
PKM2 Promotes Breast Cancer Progression by Regulating Epithelial Mesenchymal Transition.
KIF3C Promotes Proliferation, Migration, and Invasion of Glioma Cells by Activating the PI3K/AKT Pathway and Inducing EMT.
miR-876 Inhibits EMT and Liver Fibrosis via POSTN to Suppress Metastasis in Hepatocellular Carcinoma.
BTG1 inhibits malignancy as a novel prognosis signature in endometrial carcinoma.
Down-regulation of TRIB3 inhibits the progression of ovarian cancer via MEK/ERK signaling pathway.
EphA5 knockdown enhances the invasion and migration ability of esophageal squamous cell carcinoma via epithelial-mesenchymal transition through activating Wnt/β-catenin pathway.
HBx mediated Increase of SIRT1 Contributes to HBV-related Hepatocellular Carcinoma Tumorigenesis.
MFP-FePt-GO Nanocomposites Promote Radiosensitivity of Non-Small Cell Lung Cancer Via Activating Mitochondrial-Mediated Apoptosis and Impairing DNA Damage Repair.
Lin28A Regulates Stem-like Properties of Ovarian Cancer Cells by Enriching RAN and HSBP1 mRNA and Up-regulating its Protein Expression.
miR-370-3p Alleviates Ulcerative Colitis-Related Colorectal Cancer in Mice Through Inhibiting the Inflammatory Response and Epithelial-Mesenchymal Transition.
Cigarette smoke supports stemness and epithelial-mesenchymal transition in bladder cancer stem cells through SHH signaling.
MicroRNA-623 Inhibits Epithelial-Mesenchymal Transition to Attenuate Glioma Proliferation by Targeting TRIM44.
Characterization of Triple-Negative Breast Cancer MDA-MB-231 Cell Spheroid Model.
Alpha-1 Antitrypsin Induces Epithelial-to-Mesenchymal Transition, Endothelial-to-Mesenchymal Transition, and Drug Resistance in Lung Cancer Cells.
Low-Dose Radiation Promotes Invasion and Migration of A549 Cells by Activating the CXCL1/NF-κB Signaling Pathway.
Fibroblast Activation Protein (FAP) Overexpression Induces Epithelial-Mesenchymal Transition (EMT) in Oral Squamous Cell Carcinoma by Down-Regulating Dipeptidyl Peptidase 9 (DPP9).
Tumor Suppressor microRNA-138 Suppresses Low-Grade Glioma Development and Metastasis via Regulating IGF2BP2.
TIM-3 Participates in the Invasion and Metastasis of Nasopharyngeal Carcinoma via SMAD7/SMAD2/SNAIL1 Axis-Mediated Epithelial-Mesenchymal Transition.
Prognostic Significance and Related Mechanisms of Hexokinase 1 in Ovarian Cancer.
CircHIPK3 Promotes Gemcitabine (GEM) Resistance in Pancreatic Cancer Cells by Sponging miR-330-5p and Targets RASSF1.
Downregulation of Immortalization-Upregulated Protein Suppresses the Progression of Breast Cancer Cell Lines by Regulating Epithelial-Mesenchymal Transition.
Blocking circ_0000520 Suppressed Breast Cancer Cell Growth, Migration and Invasion Partially via miR-1296/SP1 Axis Both in vitro and in vivo.
KLHL22 Regulates the EMT and Proliferation in Colorectal Cancer Cells in Part via the Wnt/β-Catenin Signaling Pathway.
METTL14 Inhibits Hepatocellular Carcinoma Metastasis Through Regulating EGFR/PI3K/AKT Signaling Pathway in an m6A-Dependent Manner.
Cytokine TNF-α promotes invasion and metastasis of gastric cancer by down-regulating Pentraxin3.
TRIM67 Promotes the Proliferation, Migration, and Invasion of Non-Small-Cell Lung Cancer by Positively Regulating the Notch Pathway.
NFE2L3 promotes malignant behavior and EMT of human hepatocellular carcinoma (HepG2) cells via Wnt/β‑catenin pathway.
Ubiquitin specific peptidase 5 enhances STAT3 signaling and promotes migration and invasion in Pancreatic Cancer.
TNFAIP8 promotes the migration of clear cell renal cell carcinoma by regulating the EMT.
P4HA2 contributes to cervical cancer progression via inducing epithelial-mesenchymal transition.
Hyperoside Attenuates Bleomycin-Induced Pulmonary Fibrosis Development in Mice.
SMYD2 suppresses APC2 expression to activate the Wnt/β-catenin pathway and promotes epithelial-mesenchymal transition in colorectal cancer.
Non-canonical signaling pathway of SNAI2 induces EMT in ovarian cancer cells by suppressing miR-222-3p transcription and upregulating PDCD10.
Liquid Biopsy of Extracellular Vesicle-Derived miR-193a-5p in Colorectal Cancer and Discovery of Its Tumor-Suppressor Functions.
LSD1 Promotes Bladder Cancer Progression by Upregulating LEF1 and Enhancing EMT.
Musashi2 promotes the progression of pancreatic cancer through a novel ISYNA1-p21/ZEB-1 pathway.
AKR1C2 acts as a targetable oncogene in esophageal squamous cell carcinoma via activating PI3K/AKT signaling pathway.
Circular RNA hsa_circ_0005556 Accelerates Gastric Cancer Progression by Sponging miR-4270 to Increase MMP19 Expression.
BAIAP2L2 promotes the progression of gastric cancer via AKT/mTOR and Wnt3a/β-catenin signaling pathways.
Novel long non-coding RNA LINC02323 promotes epithelial-mesenchymal transition and metastasis via sponging miR-1343-3p in lung adenocarcinoma.
Circular RNA circREPS2 Acts as a Sponge of miR-558 to Suppress Gastric Cancer Progression by Regulating RUNX3/β-catenin Signaling.
LncRNA Mical2/miR-203a-3p sponge participates in epithelial-mesenchymal transition by targeting p66Shc in liver fibrosis.
The AKT/GSK3-Mediated Slug Expression Contributes to Oxaliplatin Resistance in Colorectal Cancer via Upregulation of ERCC1.
MEST promotes bladder cancer cell proliferation, migration and invasion via STAT3/Twist-1-mediated EMT.
MYCT1 inhibits the EMT and migration of laryngeal cancer cells via the SP1/miR-629-3p/ESRP2 pathway.
Blocking NFATc3 ameliorates azoxymethane/dextran sulfate sodium induced colitis-associated colorectal cancer in mice via the inhibition of inflammatory responses and epithelial-mesenchymal transition.
Melatonin synergizes BRAF-targeting agent dabrafenib for the treatment of anaplastic thyroid cancer by inhibiting AKT/hTERT signalling.
Members of the miR-30 family inhibit the epithelial-to-mesenchymal transition of non-small-cell lung cancer cells by suppressing XB130 expression levels.
Micheliolide suppresses the viability, migration and invasion of U251MG cells via the NF-κB signaling pathway.
A novel metastatic promoter CEMIP and its downstream molecular targets and signaling pathway of cellular migration and invasion in SCLC cells based on proteome analysis.
Calreticulin promotes EMT in pancreatic cancer via mediating Ca(2+) dependent acute and chronic endoplasmic reticulum stress.
CUEDC1 inhibits epithelial-mesenchymal transition via the TβRI/Smad signaling pathway and suppresses tumor progression in non-small cell lung cancer.
IL-32 induces epithelial-mesenchymal transition by triggering endoplasmic reticulum stress in A549 cells.
PRMT5/Wnt4 axis promotes lymph-node metastasis and proliferation of laryngeal carcinoma.
GATA6 promotes epithelial-mesenchymal transition and metastasis through MUC1/β-catenin pathway in cholangiocarcinoma.
MyoD1 suppresses cell migration and invasion by inhibiting FUT4 transcription in human gastric cancer cells.
LncRNA HOTTIP promotes the proliferation and invasion of ovarian cancer cells by activating the MEK/ERK pathway.
SUMO4 small interfering RNA attenuates invasion and migration via the JAK2/STAT3 pathway in non-small cell lung cancer cells.
SNHG1 promotes proliferation, migration and invasion of bladder cancer cells via the PI3K/AKT signaling pathway.
Wnt/β-Catenin Signaling Axis Is Required for TFEB-Mediated Gastric Cancer Metastasis and Epithelial-Mesenchymal Transition.
OXPHOS-dependent metabolic reprogramming prompts metastatic potential of breast cancer cells under osteogenic differentiation.
Deficiency of pseudogene UPAT leads to hepatocellular carcinoma progression and forms a positive feedback loop with ZEB1.
Isolation of DNA aptamers targeting N-cadherin and high-efficiency capture of circulating tumor cells by using dual aptamers.
Exosome-derived ENO1 regulates integrin α6β4 expression and promotes hepatocellular carcinoma growth and metastasis.
Serum KIAA1199 is an advanced-stage prognostic biomarker and metastatic oncogene in cholangiocarcinoma.
Sirtuin 6 attenuates epithelial-mesenchymal transition by suppressing the TGF-β1/Smad3 pathway and c-Jun in asthma models.
XB130, regulated by miR-203, miR-219, and miR-4782-3p, mediates the proliferation and metastasis of non-small-cell lung cancer cells.
MiR-645 promotes invasiveness, metastasis and tumor growth in colorectal cancer by targeting EFNA5.
BMP8A promotes survival and drug resistance via Nrf2/TRIM24 signaling pathway in clear cell renal cell carcinoma.
PHLDA2 regulates EMT and autophagy in colorectal cancer via the PI3K/AKT signaling pathway.
MAY, a novel tubulin inhibitor, induces cell apoptosis in A549 and A549/Taxol cells and inhibits epithelial-mesenchymal transition in A549/Taxol cells.
IGF-1 promotes multiple myeloma progression through PI3K/Akt-mediated epithelial-mesenchymal transition.
A dual receptors-targeting and size-switchable "cluster bomb" co-loading chemotherapeutic and transient receptor potential ankyrin 1 (TRPA-1) inhibitor for treatment of triple negative breast cancer.
Gremlin-1 is a key regulator of endothelial-to-mesenchymal transition in human pulmonary artery endothelial cells.
MiR-328-3p inhibits cell proliferation and metastasis in colorectal cancer by targeting Girdin and inhibiting the PI3K/Akt signaling pathway.
PLEK2 mediates metastasis and vascular invasion via the ubiquitin-dependent degradation of SHIP2 in non-small cell lung cancer.
Downregulated placental expression of linc00468 contributes to trophoblast dysfunction by inducing epithelial-mesenchymal transition.
Rosmarinic acid exerts an anticancer effect on osteosarcoma cells by inhibiting DJ-1 via regulation of the PTEN-PI3K-Akt signaling pathway.
MicroRNA‑137 suppresses the proliferation, migration and invasion of cholangiocarcinoma cells by targeting WNT2B.
Linc00261 inhibits metastasis and the WNT signaling pathway of pancreatic cancer by regulating a miR‑552‑5p/FOXO3 axis.
Interleukin 1β/1RA axis in colorectal cancer regulates tumor invasion, proliferation and apoptosis via autophagy.
Quantitative proteomic analysis reveals that Luks-PV exerts antitumor activity by regulating the key proteins and metabolic pathways in HepG2 cells.
Decreasing New York esophageal squamous cell carcinoma 1 expression inhibits multiple myeloma growth and osteolytic lesions.
Retinol-Binding Protein 4 Accelerates Metastatic Spread and Increases Impairment of Blood Flow in Mouse Mammary Gland Tumors.
Transcription co-activator P300 activates Elk1-aPKC-ι signaling mediated epithelial-to-mesenchymal transition and malignancy in hepatocellular carcinoma.
Long non-coding RNA HAL suppresses the migration and invasion of serous ovarian cancer by inhibiting EMT signaling pathway.
Upregulated NTF4 in colorectal cancer promotes tumor development via regulating autophagy.
Inhibition of miR-574-5p suppresses cell growth and metastasis and enhances chemosensitivity by targeting RNA binding protein QKI in cervical cancer cells.
Effect of STAT3 mediated epigenetic regulation in pre-eclampsia: an analysis of trial data.
HnRNP A1 - mediated alternative splicing of CCDC50 contributes to cancer progression of clear cell renal cell carcinoma via ZNF395.
ARHGEF10L expression regulates cell proliferation and migration in gastric tumorigenesis.
Cyclovirobuxine D inhibits colorectal cancer tumorigenesis via the CTHRC1‑AKT/ERK‑Snail signaling pathway.
PCNP promotes ovarian cancer progression by accelerating β-catenin nuclear accumulation and triggering EMT transition.
LncRNA MALAT1 affects the migration and invasion of trophoblast cells by regulating FOS expression in early-onset preeclampsia.
PRR11 and SKA2 promote the proliferation, migration and invasion of esophageal carcinoma cells.
miR-96-5p regulated TGF-β/SMAD signaling pathway and suppressed endometrial cell viability and migration via targeting TGFBR1.
SLC7A2 serves as a potential biomarker and therapeutic target for ovarian cancer.
PD-L1 promotes tumor growth and progression by activating WIP and β-catenin signaling pathways and predicts poor prognosis in lung cancer.
The cross-talk between DDR1 and STAT3 promotes the development of hepatocellular carcinoma.
Nucleus-located PDK1 regulates growth, invasion and migration of breast cancer cells.
CPEB3 inhibits epithelial-mesenchymal transition by disrupting the crosstalk between colorectal cancer cells and tumor-associated macrophages via IL-6R/STAT3 signaling.
A combination of Citrus reticulata peel and black tea inhibits migration and invasion of liver cancer via PI3K/AKT and MMPs signaling pathway.
Spondin 2 promotes the proliferation, migration and invasion of gastric cancer cells.
Endoplasmic reticulum stress regulates epithelial‑mesenchymal transition in human lens epithelial cells.
Norepinephrine transporter promotes the invasion of human colon cancer cells.
Desloratadine, a Novel Antigrowth Reagent for Bladder Cancer.
Aspirin enhances the sensitivity of colon cancer cells to cisplatin by abrogating the binding of NF-κB to the COX-2 promoter.
UBE2O promotes the proliferation, EMT and stemness properties of breast cancer cells through the UBE2O/AMPKα2/mTORC1-MYC positive feedback loop.
Protective effects of Salidroside on spermatogenesis in streptozotocin induced type-1 diabetic male mice by inhibiting oxidative stress mediated blood-testis barrier damage.
Graphene Oxide Promotes Cancer Metastasis through Associating with Plasma Membrane To Promote TGF-β Signaling-Dependent Epithelial-Mesenchymal Transition.
Telmisartan inhibits oxalate and calcium oxalate crystal-induced epithelial-mesenchymal transformation via PPAR-γ-AKT/STAT3/p38 MAPK-Snail pathway.
SPARCL1 impedes trophoblast migration and invasion by down-regulating ERK phosphorylation and AP-1 production and altering EMT-related molecule expression.
CCND1, NOP14 and DNMT3B are involved in miR-502-5p-mediated inhibition of cell migration and proliferation in bladder cancer.
Epiregulin promotes trophoblast epithelial-mesenchymal transition through poFUT1 and O-fucosylation by poFUT1 on uPA.
miR-1294 alleviates epithelial-mesenchymal transition by repressing FOXK1 in gastric cancer.
The reciprocal interaction between tumor cells and activated fibroblasts mediated by TNF-α/IL-33/ST2L signaling promotes gastric cancer metastasis.
α5-nAChR contributes to epithelial-mesenchymal transition and metastasis by regulating Jab1/Csn5 signalling in lung cancer.
Expression and clinical significance of WWOX, Elf5, Snail1 and EMT related factors in epithelial ovarian cancer.
PLAGL2 promotes epithelial-mesenchymal transition and mediates colorectal cancer metastasis via β-catenin-dependent regulation of ZEB1.
The lncRNA FEZF1-AS1 Promotes the Progression of Colorectal Cancer Through Regulating OTX1 and Targeting miR-30a-5p.
Interaction of calcium binding protein S100A16 with myosin-9 promotes cytoskeleton reorganization in renal tubulointerstitial fibrosis.
Promotion of esophageal adenocarcinoma metastasis via Wnt/ß-catenin signal pathway by sorting nexins 3.
Circ_0075829 facilitates the progression of pancreatic carcinoma by sponging miR-1287-5p and activating LAMTOR3 signalling.
MicroRNA-1236-3p inhibits human osteosarcoma growth.
Down-regulation of lncRNA DNAJC3-AS1 inhibits colon cancer via regulating miR-214-3p/LIVIN axis.
Epithelial to Mesenchymal Transition (EMT) in a Laryngeal Squamous Cell Carcinoma of a Horse: Future Perspectives.
HOXB9 enhances the ability of lung cancer cells to penetrate the blood-brain barrier.
S119N Mutation of the E3 Ubiquitin Ligase SPOP Suppresses SLC7A1 Degradation to Regulate Hepatoblastoma Progression.
The role of miR-34c-5p/Notch in epithelial-mesenchymal transition (EMT) in endometriosis.
Girdin interaction with vimentin induces EMT and promotes the growth and metastasis of pancreatic ductal adenocarcinoma.
Possible involvement of TGF‑β‑SMAD‑mediated epithelial‑mesenchymal transition in pro‑metastatic property of PAX6.
miR-143 inhibits renal cell carcinoma cells metastatic potential by suppressing ABL2.
Mesenchymal to epithelial transition driven by canine distemper virus infection of canine histiocytic sarcoma cells contributes to a reduced cell motility in vitro.
Hsa-miR-425-5p promotes tumor growth and metastasis by activating the CTNND1-mediated β-catenin pathway and EMT in colorectal cancer.
circ_0007385 served as competing endogenous RNA for miR-519d-3p to suppress malignant behaviors and cisplatin resistance of non-small cell lung cancer cells.
MicroRNA-378-3p/5p suppresses the migration and invasiveness of oral squamous carcinoma cells by inhibiting KLK4 expression.
Stromal fibroblast-derived MFAP5 promotes the invasion and migration of breast cancer cells via Notch1/slug signaling.
Diminished CD68(+) Cancer-Associated Fibroblast Subset Induces Regulatory T-Cell (Treg) Infiltration and Predicts Poor Prognosis of Oral Squamous Cell Carcinoma Patients.
Novel nortriterpenoids with new skeletons and limonoids from the fruits of Evodia rutaecarpa and their bioactivities.
The YY1/miR-548t-5p/CXCL11 signaling axis regulates cell proliferation and metastasis in human pancreatic cancer.
CCL5 derived from tumor-associated macrophages promotes prostate cancer stem cells and metastasis via activating β-catenin/STAT3 signaling.
Aligned Biofunctional Electrospun PLGA-LysoGM1 Scaffold for Traumatic Brain Injury Repair.
MicroRNA-23a-3p Inhibits Mucosal Melanoma Growth and Progression through Targeting Adenylate Cyclase 1 and Attenuating cAMP and MAPK Pathways.
Inhibition of SMYD2 suppresses tumor progression by down-regulating microRNA-125b and attenuates multi-drug resistance in renal cell carcinoma.
Sulforaphane Inhibits the Acquisition of Tobacco Smoke-Induced Lung Cancer Stem Cell-Like Properties via the IL-6/ΔNp63α/Notch Axis.
Survey of the translation shifts in hepatocellular carcinoma with ribosome profiling.
Temporal inhibition of mouse mammary gland cancer metastasis by CORM-A1 and DETA/NO combination therapy.
SERPIND1 Affects the Malignant Biological Behavior of Epithelial Ovarian Cancer via the PI3K/AKT Pathway: A Mechanistic Study.
CAPE-pNO(2) Inhibited the Growth and Metastasis of Triple-Negative Breast Cancer via the EGFR/STAT3/Akt/E-Cadherin Signaling Pathway.
Identification of RE1-Silencing Transcription Factor as a Promoter of Metastasis in Pancreatic Cancer.
Scorpion Venom Analgesic Peptide, BmK AGAP Inhibits Stemness, and Epithelial-Mesenchymal Transition by Down-Regulating PTX3 in Breast Cancer.
LncRNA ZFAS1 promotes proliferation and migration and inhibits apoptosis in nasopharyngeal carcinoma via the PI3K/AKT pathway in vitro.
The long noncoding RNA LINC00483 promotes lung adenocarcinoma progression by sponging miR-204-3p.
Betulinic Acid Suppresses Breast Cancer Metastasis by Targeting GRP78-Mediated Glycolysis and ER Stress Apoptotic Pathway.
Ferritinophagic Flux Activation in CT26 Cells Contributed to EMT Inhibition Induced by a Novel Iron Chelator, DpdtpA.
2-Methoxy-5((3,4,5-trimethosyphenyl)seleninyl) phenol reverses EGF-induced cell migration and invasion through down-regulation of MDM2 in breast cancer cell lines.
FBXO22 Suppresses Metastasis in Human Renal Cell Carcinoma via Inhibiting MMP-9-Mediated Migration and Invasion and VEGF-Mediated Angiogenesis.
CLK3 Is A Direct Target Of miR-144 And Contributes To Aggressive Progression In Hepatocellular Carcinoma.
Exosomal Tenascin-c induces proliferation and invasion of pancreatic cancer cells by WNT signaling.
High expression of long non-coding RNA NNT-AS1 facilitates progression of cholangiocarcinoma through promoting epithelial-mesenchymal transition.
Long noncoding RNA CASC15 predicts unfavorable prognosis and exerts oncogenic functions in non-small cell lung cancer.
Lipase member H is a downstream molecular target of hypoxia inducible factor-1α and promotes papillary thyroid carcinoma cell migration in BCPAP and KTC-1 cell lines.
12-lipoxygenase promotes tumor progress by TGF-β1-mediated epithelial to mesenchymal transition and predicts poor prognosis in esophageal squamous cell carcinoma.
Overexpressed PKMYT1 promotes tumor progression and associates with poor survival in esophageal squamous cell carcinoma.
The oncogenic role of GNL3 in the progression and metastasis of osteosarcoma.
Lyn Kinase Promotes the Proliferation of Malignant Melanoma Cells through Inhibition of Apoptosis and Autophagy via the PI3K/Akt Signaling Pathway.
RUFY3 Predicts Poor Prognosis and Promotes Metastasis through Epithelial-mesenchymal Transition in Lung Adenocarcinoma.
Dysregulation of MiR-519d Affects Oral Squamous Cell Carcinoma Invasion and Metastasis by Targeting MMP3.
Small Nucleolar RNA 71A Promotes Lung Cancer Cell Proliferation, Migration and Invasion via MAPK/ERK Pathway.
Activation of CXCL6/CXCR1/2 Axis Promotes the Growth and Metastasis of Osteosarcoma Cells in vitro and in vivo.
Knockdown of SP1/Syncytin1 axis inhibits the proliferation and metastasis through the AKT and ERK1/2 signaling pathways in non-small cell lung cancer.
Fluorene-9-bisphenol inhibits epithelial-mesenchymal transition of human endometrial cancer Ishikawa cells by repressing TGF-β signaling pathway.
Long non-coding RNA linc00645 promotes TGF-β-induced epithelial-mesenchymal transition by regulating miR-205-3p-ZEB1 axis in glioma.
Sulforaphane inhibits epithelial-mesenchymal transition by activating extracellular signal-regulated kinase 5 in lung cancer cells.
Macrophage migration inhibitory factor promotes the invasion and metastasis of oral squamous cell carcinoma through matrix metalloprotein-2/9.
A novel tetravalent bispecific antibody targeting programmed death 1 and tyrosine-protein kinase Met for treatment of gastric cancer.
Yes-associated protein (YAP) predicts poor prognosis and regulates progression of esophageal squamous cell cancer through epithelial-mesenchymal transition.
CircWHSC1 promotes ovarian cancer progression by regulating MUC1 and hTERT through sponging miR-145 and miR-1182.
Curcumin mitigates the epithelial-to-mesenchymal transition in biliary epithelial cells through upregulating CD109 expression.
Huangqi-Fangfeng protects against allergic airway remodeling through inhibiting epithelial-mesenchymal transition process in mice via regulating epithelial derived TGF-β1.
Knockdown of FAM64A suppresses proliferation and migration of breast cancer cells.
The miR-27a-3p/USP25 axis participates in the pathogenesis of recurrent miscarriage by inhibiting trophoblast migration and invasion.
Downregulation of Rab23 inhibits proliferation, invasion, and metastasis of human ovarian cancer.
PITPNA-AS1 abrogates the inhibition of miR-876-5p on WNT5A to facilitate hepatocellular carcinoma progression.
STRA6 exerts oncogenic role in gastric tumorigenesis by acting as a crucial target of miR-873.
Sinulariolide Inhibits Gastric Cancer Cell Migration and Invasion through Downregulation of the EMT Process and Suppression of FAK/PI3K/AKT/mTOR and MAPKs Signaling Pathways.
Graphene oxide substrates with N-cadherin stimulates neuronal growth and intracellular transport.
Hypoxia promotes vasculogenic mimicry formation by vascular endothelial growth factor A mediating epithelial-mesenchymal transition in salivary adenoid cystic carcinoma.
RPS7 promotes cell migration through targeting epithelial-mesenchymal transition in prostate cancer.
Upregulation of lncRNA DGCR5 correlates with better prognosis and inhibits bladder cancer progression via transcriptionally facilitating P21 expression.
SSRP1 promotes colorectal cancer progression and is negatively regulated by miR-28-5p.
Upregulated forkhead-box A3 elevates the expression of forkhead-box A1 and forkhead-box A2 to promote metastasis in esophageal cancer.
miR-340-FHL2 axis inhibits cell growth and metastasis in ovarian cancer.
M2 macrophages promote NSCLC metastasis by upregulating CRYAB.
Wnt7a predicts poor prognosis, and contributes to growth and metastasis in tongue squamous cell carcinoma.
LncRNA MIR22HG inhibits growth, migration and invasion through regulating the miR-10a-5p/NCOR2 axis in hepatocellular carcinoma cells.
Nuciferine inhibits the progression of glioblastoma by suppressing the SOX2-AKT/STAT3-Slug signaling pathway.
The Attenuation of Trophoblast Invasion Caused by the Downregulation of EZH2 Is Involved in the Pathogenesis of Human Recurrent Miscarriage.
AKR1B10 (Aldo-keto reductase family 1 B10) promotes brain metastasis of lung cancer cells in a multi-organ microfluidic chip model.
Tacalcitol increases the sensitivity of colorectal cancer cells to 5-fluorouracil by downregulating the thymidylate synthase.
Bronchial epithelial cell extracellular vesicles ameliorate epithelial-mesenchymal transition in COPD pathogenesis by alleviating M2 macrophage polarization.
Platelets promote invasion and induce epithelial to mesenchymal transition in ovarian cancer cells by TGF-β signaling pathway.
circ-CSPP1 promotes proliferation, invasion and migration of ovarian cancer cells by acting as a miR-1236-3p sponge.
Calcium-Activated Chloride Channel A4 (CLCA4) Plays Inhibitory Roles in Invasion and Migration Through Suppressing Epithelial-Mesenchymal Transition via PI3K/AKT Signaling in Colorectal Cancer.
Effects of MCRS1 on proliferation, migration, invasion, and epithelial mesenchymal transition of gastric cancer cells by interacting with Pkmyt1 protein kinase.
Mesenchymal stem cell-secreted factors delayed spermatogenesis injuries induced by busulfan involving intercellular adhesion molecule regulation.
The potential role of pregnancy-associated plasma protein-A2 in angiogenesis and development of preeclampsia.
NAV2 facilitates invasion of cutaneous melanoma cells by targeting SNAI2 through the GSK-3β/β-catenin pathway.
Exogenous regucalcin negatively regulates the progression of cervical adenocarcinoma.
MicroRNA-23a promotes colorectal cancer cell migration and proliferation by targeting at MARK1.
Downregulation of DAPK1 promotes the stemness of cancer stem cells and EMT process by activating ZEB1 in colorectal cancer.
Dual regulatory role of CCNA2 in modulating CDK6 and MET-mediated cell-cycle pathway and EMT progression is blocked by miR-381-3p in bladder cancer.
Chromium(VI) promotes cell migration through targeting epithelial-mesenchymal transition in prostate cancer.
Opa interacting protein 5 promotes metastasis of nasopharyngeal carcinoma cells by promoting EMT via modulation of JAK2/STAT3 signal.
FOXC1 silencing inhibits the epithelial‑to‑mesenchymal transition of glioma cells: Involvement of β‑catenin signaling.
Tobacco smoke induced hepatic cancer stem cell-like properties through IL-33/p38 pathway.
Long noncoding FOXD2-AS1 is activated by CREB1 and promotes cell proliferation and metastasis in glioma by sponging miR-185 through targeting AKT1.
Inhibition of ATP citrate lyase (ACLY) protects airway epithelia from PM(2.5)-induced epithelial-mesenchymal transition.
ARHGEF10L contributes to liver tumorigenesis through RhoA-ROCK1 signaling and the epithelial-mesenchymal transition.
LincK contributes to breast tumorigenesis by promoting proliferation and epithelial-to-mesenchymal transition.
Zoledronic acid inhibits the growth of cancer stem cell derived from cervical cancer cell by attenuating their stemness phenotype and inducing apoptosis and cell cycle arrest through the Erk1/2 and Akt pathways.
P53-induced miR-1249 inhibits tumor growth, metastasis, and angiogenesis by targeting VEGFA and HMGA2.
Lipoprotein receptor-related protein 6 is required to maintain intercalated disk integrity.
Knockdown of periostin attenuates 5/6 nephrectomy-induced intrarenal renin-angiotensin system activation, fibrosis, and inflammation in rats.
Downregulation of HDAC3 by ginsenoside Rg3 inhibits epithelial-mesenchymal transition of cutaneous squamous cell carcinoma through c-Jun acetylation.
miR-451a inhibits cancer growth, epithelial-mesenchymal transition and induces apoptosis in papillary thyroid cancer by targeting PSMB8.
Targeting amphiregulin (AREG) derived from senescent stromal cells diminishes cancer resistance and averts programmed cell death 1 ligand (PD-L1)-mediated immunosuppression.
Protective effects of betaine on diabetic induced disruption of the male mice blood-testis barrier by regulating oxidative stress-mediated p38 MAPK pathways.
Silencing TTK expression inhibits the proliferation and progression of prostate cancer.
Long noncoding RNA SOX21-AS1 promotes cervical cancer progression by competitively sponging miR-7/VDAC1.
miR-205-5p regulates epithelial-mesenchymal transition by targeting PTEN via PI3K/AKT signaling pathway in cisplatin-resistant nasopharyngeal carcinoma cells.
miR-504 suppresses mesenchymal phenotype of glioblastoma by directly targeting the FZD7-mediated Wnt-β-catenin pathway.
Down-regulation of lncRNA-ATB inhibits epithelial-mesenchymal transition of breast cancer cells by increasing miR-141-3p expression.
LncRNA H19 interacted with miR-130a-3p and miR-17-5p to modify radio-resistance and chemo-sensitivity of cardiac carcinoma cells.
A mechanism of regucalcin knock-down in the promotion of proliferation and movement of human cervical cancer HeLa cells.
Dependence of artesunate on long noncoding RNA-RP11 to inhibit epithelial-mesenchymal transition of hepatocellular carcinoma.
Bone marrow mesenchymal stem cells suppress growth and promote the apoptosis of glioma U251 cells through downregulation of the PI3K/AKT signaling pathway.
Network-pharmacology-based identification of caveolin-1 as a key target of Oldenlandia diffusa to suppress breast cancer metastasis.
GTSE1 is involved in breast cancer progression in p53 mutation-dependent manner.
The PAX6-ZEB2 axis promotes metastasis and cisplatin resistance in non-small cell lung cancer through PI3K/AKT signaling.
Circular RNA circTADA2A promotes osteosarcoma progression and metastasis by sponging miR-203a-3p and regulating CREB3 expression.
S100A4-MYH9 Axis Promote Migration and Invasion of Gastric Cancer Cells by Inducing TGF-β-Mediated Epithelial-Mesenchymal Transition.
Tip60 Suppresses Cholangiocarcinoma Proliferation and Metastasis via PI3k-AKT.
The Natural Compound Myricetin Effectively Represses the Malignant Progression of Prostate Cancer by Inhibiting PIM1 and Disrupting the PIM1/CXCR4 Interaction.
MiR-598 Suppresses Invasion and Migration by Negative Regulation of Derlin-1 and Epithelial-Mesenchymal Transition in Non-Small Cell Lung Cancer.
C/D-Box Snord105b Promotes Tumorigenesis in Gastric Cancer via ALDOA/C-Myc Pathway.
Silencing Formin-like 2 inhibits growth and metastasis of gastric cancer cells through suppressing internalization of integrins.
Tumor-associated macrophages derived CCL18 promotes metastasis in squamous cell carcinoma of the head and neck.
Overexpression of TEAD4 correlates with poor prognosis of glioma and promotes cell invasion.
KIAA1199 overexpression is associated with abnormal expression of EMT markers and is a novel independent prognostic biomarker for hepatocellular carcinoma.
Contribution of dysregulated circRNA_100876 to proliferation and metastasis of esophageal squamous cell carcinoma.
Effect of simvastatin and microRNA-21 inhibitor on metastasis and progression of human salivary adenoid cystic carcinoma.
SNORA42 enhances prostate cancer cell viability, migration and EMT and is correlated with prostate cancer poor prognosis.
Melittin-induced long non-coding RNA NONHSAT105177 inhibits proliferation and migration of pancreatic ductal adenocarcinoma.
TGF-β-mediated exosomal lnc-MMP2-2 regulates migration and invasion of lung cancer cells to the vasculature by promoting MMP2 expression.
Selenium (Na(2)SeO(3)) Upregulates Expression of Immune Genes and Blood-Testis Barrier Constituent Proteins of Bovine Sertoli Cell In Vitro.
Low-Dose Radiation Enhanced Inhibition of Breast Tumor Xenograft and Reduced Myocardial Injury Induced by Doxorubicin.
Long non-coding RNA OGFRP1 regulates LYPD3 expression by sponging miR-124-3p and promotes non-small cell lung cancer progression.
High expression of WNT7A predicts poor prognosis and promote tumor metastasis in pancreatic ductal adenocarcinoma.
DNA-methylation-mediated silencing of miR-486-5p promotes colorectal cancer proliferation and migration through activation of PLAGL2/IGF2/β-catenin signal pathways.
Identification and characterization of a highly metastatic epithelial cancer cell line from rat tongue cancer.
RNA interference of long noncoding RNA HOTAIR suppresses autophagy and promotes apoptosis and sensitivity to cisplatin in oral squamous cell carcinoma.
Isoliquiritigenin inhibits cell proliferation and migration through the PI3K/AKT signaling pathway in A549 lung cancer cells.
Toll-like receptor 4 shRNA attenuates lipopolysaccharide-induced epithelial-mesenchymal transition of intrahepatic biliary epithelial cells in rats.
Combination Therapy with DETA/NO and Clopidogrel Inhibits Metastasis in Murine Mammary Gland Cancer Models via Improved Vasoprotection.
Abnormally elevated USP37 expression in breast cancer stem cells regulates stemness, epithelial-mesenchymal transition and cisplatin sensitivity.
RAB37 interacts directly with ATG5 and promotes autophagosome formation via regulating ATG5-12-16 complex assembly.
The PLGF/c-MYC/miR-19a axis promotes metastasis and stemness in gallbladder cancer.
CD74-ROS1 G2032R mutation transcriptionally up-regulates Twist1 in non-small cell lung cancer cells leading to increased migration, invasion, and resistance to crizotinib.
A germline-specific role for the mTORC2 component Rictor in maintaining spermatogonial differentiation and intercellular adhesion in mouse testis.
Dysregulated Expression of RPS4Y1 (Ribosomal Protein S4, Y-Linked 1) Impairs STAT3 (Signal Transducer and Activator of Transcription 3) Signaling to Suppress Trophoblast Cell Migration and Invasion in Preeclampsia.
Knockout of NCOA5 impairs proliferation and migration of hepatocellular carcinoma cells by suppressing epithelial-to-mesenchymal transition.
RHBDF1 regulates APC-mediated stimulation of the epithelial-to-mesenchymal transition and proliferation of colorectal cancer cells in part via the Wnt/β-catenin signalling pathway.
Unfavorable effect of calcitriol and its low-calcemic analogs on metastasis of 4T1 mouse mammary gland cancer.
PLCD3, a flotillin2-interacting protein, is involved in proliferation, migration and invasion of nasopharyngeal carcinoma cells.
PLZF inhibits proliferation and metastasis of gallbladder cancer by regulating IFIT2.
Increased Expression of Cullin 3 in Nasopharyngeal Carcinoma and Knockdown Inhibits Proliferation and Invasion.
MicroRNA-1271 functions as a metastasis and epithelial-mesenchymal transition inhibitor in human HCC by targeting the PTP4A1/c-Src axis.
PIM1 mediates epithelial-mesenchymal transition by targeting Smads and c-Myc in the nucleus and potentiates clear-cell renal-cell carcinoma oncogenesis.
Endogenous and exogenous galectin-3 promote the adhesion of tumor cells with low expression of MUC1 to HUVECs through upregulation of N-cadherin and CD44.
Sodium Selenite inhibits mitophagy, downregulation and mislocalization of blood-testis barrier proteins of bovine Sertoli cell exposed to microcystin-leucine arginine (MC-LR) via TLR4/NF-kB and mitochondrial signaling pathways blockage.
Salinomycin suppresses cancer cell stemness and attenuates TGF-β-induced epithelial-mesenchymal transition of renal cell carcinoma cells.
Mitochondrial cytochrome P450 (CYP) 1B1 is responsible for melatonin-induced apoptosis in neural cancer cells.
LncRNA BDNF-AS inhibits proliferation, migration, invasion and EMT in oesophageal cancer cells by targeting miR-214.
Phosphoglycerate Mutase 1 (PGAM1) Promotes Pancreatic Ductal Adenocarcinoma (PDAC) Metastasis by Acting as a Novel Downstream Target of the PI3K/Akt/mTOR Pathway.
Hypoxic Tumor-Derived Exosomal miR-301a Mediates M2 Macrophage Polarization via PTEN/PI3Kγ to Promote Pancreatic Cancer Metastasis.
Fentanyl Promotes Breast Cancer Cell Stemness and Epithelial-Mesenchymal Transition by Upregulating α1, 6-Fucosylation via Wnt/β-Catenin Signaling Pathway.
β-Catenin Cooperates with CREB Binding Protein to Promote the Growth of Tumor Cells.
Clopidogrel in a combined therapy with anticancer drugs-effect on tumor growth, metastasis, and treatment toxicity: Studies in animal models.
Potential Involvement of Snail Members in Neuronal Survival and Astrocytic Migration during the Gecko Spinal Cord Regeneration.
MiR-211 inhibits cell epithelial-mesenchymal transition by targeting MMP9 in gastric cancer.
Curcumin potentiates the potent antitumor activity of ACNU against glioblastoma by suppressing the PI3K/AKT and NF-κB/COX-2 signaling pathways.
Overexpression of RCC2 Enhances Cell Motility and Promotes Tumor Metastasis in Lung Adenocarcinoma by Inducing Epithelial-Mesenchymal Transition.
Honokiol inhibits bladder cancer cell invasion through repressing SRC-3 expression and epithelial-mesenchymal transition.
MicroRNA-23a promotes pancreatic cancer metastasis by targeting epithelial splicing regulator protein 1.
ANGPTL1 Interacts with Integrin α1β1 to Suppress HCC Angiogenesis and Metastasis by Inhibiting JAK2/STAT3 Signaling.
Transducin (β)-like 1 X-linked receptor 1 promotes gastric cancer progression via the ERK1/2 pathway.
NUBPL, a novel metastasis-related gene, promotes colorectal carcinoma cell motility by inducing epithelial-mesenchymal transition.
NTN4 is associated with breast cancer metastasis via regulation of EMT-related biomarkers.
Disruption of the c-Myc/miR-200b-3p/PRDX2 regulatory loop enhances tumor metastasis and chemotherapeutic resistance in colorectal cancer.
SLC39A4 expression is associated with enhanced cell migration, cisplatin resistance, and poor survival in non-small cell lung cancer.
Metformin reverses prostate cancer resistance to enzalutamide by targeting TGF-β1/STAT3 axis-regulated EMT.
Oral kanglaite injection (KLTI) attenuates the lung cancer-promoting effect of high-fat diet (HFD)-induced obesity.
Effects of RECQ1 helicase silencing on non-small cell lung cancer cells.
1-methylnicotinamide and its structural analog 1,4-dimethylpyridine for the prevention of cancer metastasis.
FOXQ1 mediates the crosstalk between TGF-β and Wnt signaling pathways in the progression of colorectal cancer.
Jiang Z, Ye X, Song M, Qiao Y, Cheng W, Wang D, Zhang X, Li X, Yu X, Wang X, Ji J, Mou Y
Nucleosides, nucleotides & nucleic acids 2026;45(1):64-87
Nucleosides, nucleotides & nucleic acids 2026;45(1):64-87
THBS3 Functions as a Novel Biomarker for Prognosis and Immunotherapeutic Response in Colorectal Cancer: An Integrative Analysis and Validation of the Thrombospondin Gene Family.
Jiang T, Zhu S, Zhou H, Zhang N, Zhang L, Zou C, Song H
Cancer informatics 2026;25:11769351251412614
Cancer informatics 2026;25:11769351251412614
Yifei Decoction Regulates the NGF/TRKA/PI3K/AKT Signaling Axis to Inhibit the Epithelial-Mesenchymal Transformation and Proliferation of Pulmonary Epithelial Cells in Bleomycin-Induced Pulmonary Fibrogenesis.
Chen L, Lan C, Deng X, Wu M, Shao M, Yang M, Ma X, Huang F, Wu H
Canadian respiratory journal 2026;2026:6614209
Canadian respiratory journal 2026;2026:6614209
GNPAT promotes immunosuppression in hepatocellular carcinoma by activating the plasmalogen-PPARγ pathway to drive M2 macrophage polarization.
Hu M, Zhang N, Wang YQ, Wang XM, Shi Y, Yao M, Hou LG, Jiang LL
Frontiers in immunology 2026;17:1765930
Frontiers in immunology 2026;17:1765930
Targeting CPS1 attenuates lung cancer metastasis by regulating EMT through an epigenetic mechanism.
Ding Y, Tian Y, Li M, Fu Y, Wang T, Du X, Wang M, Dong L, Gao F, Liu B, Lu Y, Zhang C, Mao L, Jiang J, Li L, Liao L, Li K
Theranostics 2026;16(4):1740-1761
Theranostics 2026;16(4):1740-1761
A novel mouse cell line model reveals the tumor intrinsic and immune characteristics of EGFR-mutant lung cancer.
Yan Y, Shang J, Liu C, Chen Y, Bao Y, Zhao Y, Fan F, Sun Y, Zhou Y, Wu Y, Wang Y, Han H, Chen H, Pan Y
Theranostics 2026;16(2):1006-1022
Theranostics 2026;16(2):1006-1022
Macrophage-Derived Transcriptional Signatures Predict Prognosis and Drug Sensitivity in Thyroid Cancer: Integrative Analysis and Experimental Validation of SMYD3.
Xu S, Zhang X, Sun J, Qin M, Du H, Luo B
ImmunoTargets and therapy 2026;15:565624
ImmunoTargets and therapy 2026;15:565624
ESRP1 drives epithelial-mesenchymal transition by activating EPAC-RAP1A signaling axis.
Qi R, Wang J, Cheng G, Zhao T, Hu Z, Yu J, Jia Y, Chen J
Frontiers in medicine 2026;13:1734619
Frontiers in medicine 2026;13:1734619
Endothelial SMAD1-MCAM axis facilitates sunitinib resistance and progression of clear cell renal cell carcinoma via LAMB1-ITGB1 signaling.
Zhang H, Liu Y, Zhang W, Guo Y, Lin A, Jin Y, Lu P, Fang Y, Zhang H, Qu L, Luo P, Wu L, Chen Y, Kang X, Wang L, Jiang A
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2026 May;86:101388
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2026 May;86:101388
ATP-binding cassette subfamily A member 5 suppresses pancreatic ductal adenocarcinoma progression and chemoresistance by promoting β-catenin ubiquitin-dependent degradation.
Li Z, Ma Z, Chen Y, Yu W, Yu J, Lu J, Zhang Q, Wu Q, Cai Y, Wang Z, Shang C, Hou B, Zhang C, Huang S, Wang L, Zhou Q
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2026 May;86:101381
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2026 May;86:101381
PLOD2 Promotes Cutaneous Squamous Cell Carcinoma Progression in Association With STAT3-Related ERK and AKT Pathways.
Xian N, Wang Z, Wang B, Wang X, Zheng Y
Molecular carcinogenesis 2026 May;65(5):615-629
Molecular carcinogenesis 2026 May;65(5):615-629
A promising magnesium-related alloy with metabolic reprogramming and antitumor effects in hepatocellular and pancreatic cancer.
Zhang J, Gu J, Xia R, Yin J, Wang X, Yang J, Wang Y, Yi Z, Wang S, Zhang Q, Wang H, She J, Guo S
Bioactive materials 2026 May;59:186-204
Bioactive materials 2026 May;59:186-204
Plasmin promotes hepatocellular carcinoma invasion and metastasis via CXCR4-mediated activation of PI3K/AKT/mTOR signaling.
Shen Z, Yang Y, Mao T, Wu F, Li F, Yang L, Yu M, Zhao B
Oncogene 2026 May;45(19):1815-1827
Oncogene 2026 May;45(19):1815-1827
Development of a self-assembling aggregation-induced emission nanoprobe for targeted therapy and real-time imaging in non-small cell lung cancer.
Ren Z, Li S, Cui T, Zhu T, Ding D, Zhao J, Yuan H
Journal of photochemistry and photobiology. B, Biology 2026 May;278:113402
Journal of photochemistry and photobiology. B, Biology 2026 May;278:113402
Peroxiredoxin 4 suppresses ferroptosis in esophageal squamous cell carcinoma by activating the phosphoinositide 3-kinase signaling pathway.
Li K, Xu S, Liu H, Fan T, Li Y, Ren R, Xu Y, Li S, Liu Y
Biomedical reports 2026 May;24(5):60
Biomedical reports 2026 May;24(5):60
m⁶A-modified circMELK regulates nasopharyngeal carcinoma progression via a YTHDF1/circMELK-miR-4775-HMGA2 feedback loop.
Yi Q, Zhong K, Chen Z, Ouyang X, Zhu W, Liang L, Zhong J
Molecular immunology 2026 May;193:50-67
Molecular immunology 2026 May;193:50-67
Multi-omics analysis and preliminary experimental validation of acetyl tributyl citrate (ATBC) promoting bladder cancer progression via the AKR1B1/EMT axis.
Jie J, Wang Q, Chen Z, Hu C, Lai Z, Ke S, Zhu Y, Li F, Fan Q, Tan W
Environmental pollution (Barking, Essex : 1987) 2026 May 15;397:127970
Environmental pollution (Barking, Essex : 1987) 2026 May 15;397:127970
Prenylterphenyllin, a regulator of P53, inhibits colorectal cancer progression through oxidative stress and energy metabolism pathway.
Zhang Y, Han Y, Li S, Shan R, Lin L, Gu Z, Wang R, Chen Y, Xiao J, An F, Hu C, He C
Redox biology 2026 Mar;90:103993
Redox biology 2026 Mar;90:103993
ENO1 inhibition synergizes with chidamide to induce ferroptosis in PTCL-NOS through metabolic remodeling.
Zhu F, Tian M, Lu K, Wang C, Liu J, Li X, Gu X, Lv B, Huang Z, Zeng L, Li Z, Lu H, Xu K
Blood science (Baltimore, Md.) 2026 Mar;8(1):e00272
Blood science (Baltimore, Md.) 2026 Mar;8(1):e00272
Oncogenic role of talin-1 in glioma: Association with poor prognosis and regulation of the TGF-beta signaling pathway.
Li J, Zhang D, Zhou H, Hou L, Wang Y, Zhang Z, Wang Y, Li X, Yi L, Liu X, Wang Y, Xue X
Translational oncology 2026 Mar;65:102691
Translational oncology 2026 Mar;65:102691
Nobiletin and polydatin synergistically alleviate triple-negative breast cancer liver metastasis via suppressing ECM1a-mediated fatty acid biosynthesis.
Wang J, Liu WW, Huang QL, Ning HJ, Wang JY, Han XH
Acta pharmacologica Sinica 2026 Mar;47(3):735-749
Acta pharmacologica Sinica 2026 Mar;47(3):735-749
Promotion of hepatocellular carcinoma by small nuclear ribonucleoprotein polypeptide F through upregulation of transmembrane P24 trafficking protein 2 and triggering of the cGAS-STING pathway.
Xie X, Pu L, Zeng J, Xu M, Yin X, Liu H, Yang J, Cao J, Song H
International journal of biological macromolecules 2026 Mar;352:151166
International journal of biological macromolecules 2026 Mar;352:151166
Novel nanoparticle-combined therapy through EGFR and PD-L1 blockade: PFPR-siRNA-mediated suppressing NSCLC proliferation via PDT and enhanced antitumor immunity.
Zhang M, Xie N, Wu D, Wu C, Guo Y, Wang N, Li XY, Liang Y, Xie X, Wang T, Li YJ, Ning F, Wang RR, Xie SY, Wang PY
Colloids and surfaces. B, Biointerfaces 2026 Mar;259:115284
Colloids and surfaces. B, Biointerfaces 2026 Mar;259:115284
AURKA Activates FOXO3a to Form a Positive Feedback Loop in the Proliferation and Migration of Keloid Fibroblasts.
Chu X, Sun J, Dai S, Liang Y, Qian X, Xu J, Zhang J
Advances in wound care 2026 Mar;15(3):168-180
Advances in wound care 2026 Mar;15(3):168-180
TRIM35 inhibits endometrial cancer progression via ubiquitination and degradation of EIF3E.
Wang Q, Ning N, Li Y
Cellular signalling 2026 Mar;139:112339
Cellular signalling 2026 Mar;139:112339
ANO6 Confers Paclitaxel Resistance by Targeting Ferroptosis in Cervical Cancer.
Cao Y, Peng Y, Shen J
BioFactors (Oxford, England) 2026 Mar-Apr;52(2):e70070
BioFactors (Oxford, England) 2026 Mar-Apr;52(2):e70070
PIEZO1 enhances pancreatic cancer neurotropism.
Li J, Liu Q, Xu R, Tang J, Wang L, Zheng Y, Weng S, Gao F
Cancer cell international 2026 Mar 9;26(1)
Cancer cell international 2026 Mar 9;26(1)
Kukoamine B Inhibits EMT in Lung Adenocarcinoma Cells by Regulating Intracellular PD-L1-Mediated p65 Nuclear Translocation.
Hou C, Chen J, Zhang L, Huang Q, Xu J, Zhang R, He Y
Biology 2026 Mar 6;15(5)
Biology 2026 Mar 6;15(5)
TWIST1-Mediated Induction of AEBP1 in Fibroblast-Like Synoviocytes Activates Transforming Growth Factor β Signaling to Drive Angiogenesis and Promote Rheumatoid Arthritis.
Li Z, Cai M, Huang W, Wen X, Li Y, Sun J, Zhu C, Yang C, Chen Z
Arthritis & rheumatology (Hoboken, N.J.) 2026 Mar 5;
Arthritis & rheumatology (Hoboken, N.J.) 2026 Mar 5;
Activation of the PI3K/AKT pathway by EDIL3 induces EMT and promotes tumor progression in clear cell renal cell carcinoma.
Tao L, Xie W, Du Y, Zhang R
Molecular genetics and genomics : MGG 2026 Mar 4;301(1)
Molecular genetics and genomics : MGG 2026 Mar 4;301(1)
TFAP2A regulates SGPP2 transcription to promote lipid accumulation and activate the Wnt/β-catenin signaling pathway to promote malignant progression in lung adenocarcinoma.
Li Q, Li J, Zhang C, Deng Y, Yang B, Ma L, Liu Y, Wang C, Xu L, Mei J
Journal of translational medicine 2026 Mar 4;24(1)
Journal of translational medicine 2026 Mar 4;24(1)
Multi-omics analysis of NEDD1 in hepatocellular carcinoma: biological function, prognostic value, and clinical significance.
Chen Y, Wan Z, Xie H, Zhou X, Peng T
Scientific reports 2026 Mar 3;16(1)
Scientific reports 2026 Mar 3;16(1)
Mechanism of LPS-activated gingival fibroblasts promote the migration of gastric cancer cells via CXCL12/CXCR4-Snail2-EMT axis.
Liu T, Tang Q, Liu M, Ren F, Liu R
In vitro cellular & developmental biology. Animal 2026 Mar 26;
In vitro cellular & developmental biology. Animal 2026 Mar 26;
Mechanistic study of miR-486-5p targeting Claudin-10 in placenta accreta spectrum pathogenesis and its impact on trophoblast behavior.
Dong T, Jiang Y, Ye F, Zhao B, Xi F, Lv M, Yang M, Pu Y, Jiang P, Luo Q
Placenta 2026 Mar 25;176:76-86
Placenta 2026 Mar 25;176:76-86
Tannic Acid Inhibits Lung Adenocarcinoma Progression by Suppressing MMP-2-Mediated Epithelial-Mesenchymal Transition.
Lin M, Zhou Y, Wang Y, Yan H, Qin X, Zhong X, Yang G, Liu Q
Biochemical genetics 2026 Mar 25;
Biochemical genetics 2026 Mar 25;
The APC/C subunit APC7 promotes hepatocellular carcinoma progression by mediating ubiquitination and degradation of LATS1 to activate YAP/TAZ.
Sun Y, Zhang R, Guo Y, Wu D, Wei H, Tan Z, Huang M, Wang Y, Fang Z, Zhang C, Li C, Li W, Wei D, Bian H, Liu ZK
Biology direct 2026 Mar 23;21(1)
Biology direct 2026 Mar 23;21(1)
USP1 promotes hepatocellular carcinoma progression by modulating mitophagy via stabilizing MCM3 to regulate the Keap1-Nrf2 axis.
Chen Z, Sun C, Wang Y, Duan X, Ma H, Zhou X, Chen S, Peng P
iScience 2026 Mar 20;29(3):114927
iScience 2026 Mar 20;29(3):114927
USP5-mediated CD73 deubiquitination drives osimertinib resistance via PI3K/AKT and glycolysis activation in LUAD.
Chen R, Han XH, Zhang Z, Han XJ, Xie J
iScience 2026 Mar 20;29(3):114916
iScience 2026 Mar 20;29(3):114916
SGK1 Is Upregulated in Retained Placenta and Mediates Estradiol Effects in Bovine Endometrial Cells.
Wang R, Wei M, Niu W, Chen J, Nan J, Zhang Y, Zhao X, Wang Q
Cells 2026 Mar 20;15(6)
Cells 2026 Mar 20;15(6)
FUT8 reprograms glycolytic metabolism to promote PKM2 lactylation and drive clear cell renal cell carcinoma progression.
Guo Z, Jiang H, Wang X, Xuan K, Zhong H, Liu C, Zhang M, Li Z, Huang W, Sun Y
Cell death discovery 2026 Mar 19;12(1)
Cell death discovery 2026 Mar 19;12(1)
Omics insights into MYBL2-promoted cancer stem-like cells driving ferroptosis resistance in hepatocellular carcinoma.
Chen Y, Li X, Luo C, Lin G, Zhou X, Wen Z, Su H, Meng W, Chen C, Lu J, Luo X, Jiang D, Liu H, Ning Z, Chen Y, Tam PK, Pan X
Journal of advanced research 2026 Mar 19;
Journal of advanced research 2026 Mar 19;
B3GNT3 facilitates NFKB2 processing and non-canonical NF-κB activation to drive lung adenocarcinoma progression.
Lin Y, Zhang Y, Yu B, Wang J, Wu Z, Wang H
Cellular oncology (Dordrecht, Netherlands) 2026 Mar 16;49(2)
Cellular oncology (Dordrecht, Netherlands) 2026 Mar 16;49(2)
RRP9 suppresses hepatocellular carcinoma progression by inhibiting the PI3K/AKT/mTOR pathway.
Fu Z, Li M, Dong K, Feng J, Wang W
International journal of oncology 2026 Jun;68(6)
International journal of oncology 2026 Jun;68(6)
Mechanism of HAND2 Regulating Glycolytic Metabolism and Metastasis Through TLR4/NOX2/DUOX2 Signaling Axis in Cervical Cancer.
Yang H, Li Y, Xiao Z, Kuang M
Molecular carcinogenesis 2026 Jun;65(6):699-714
Molecular carcinogenesis 2026 Jun;65(6):699-714
TAOK3 promotes ccRCC progression by phosphorylating ASAP2.
Zheng X, Cheng J, Zhang M, Sun M, Huang Z, Han Y, Wu R, Li Y, Zhang C
Biochimica et biophysica acta. Molecular basis of disease 2026 Jun;1872(5):168210
Biochimica et biophysica acta. Molecular basis of disease 2026 Jun;1872(5):168210
Syntaphilin inhibits glioma invasion via modulating mitochondria redistribution and shapes the immune microenvironment: A potential prognostic biomarker.
Tian H, Chen X, Si M, Xu W
Gene 2026 Jun 5;993:150105
Gene 2026 Jun 5;993:150105
IGHG1(+) malignant epithelial Cell-myCAF crosstalk via MIF-CD74/APP-CD74 drives early brain metastasis in NSCLC: Delineated via primary tumor-brain metastasis single-cell and spatial transcriptomics.
Yang L, Yang H, Zhao M, Wen Y, Wu L, Chen Q, Cao F, Zhao Y, Ye D, Yuan M, Yu J, Sun X, Xing L
Cancer letters 2026 Jun 1;647:218451
Cancer letters 2026 Jun 1;647:218451
AEG-1 3'UTR functions as a ceRNA to facilitate Helicobacter pylori-induced gastric cancer EMT by regulating the miR-375-3p/JAK2 axis.
Chen J, Li X, Zhang F, Han X, He M, Wang X, Wu J, Ni L, Liu J, Chen J, Liu K, Guo L
Microbiological research 2026 Jul;308:128502
Microbiological research 2026 Jul;308:128502
A positive SPTBN2-FLI1 feedback axis promotes bladder cancer via PI3K/AKT activation.
Guo X, Zhu C, Yin Z
Cellular signalling 2026 Jul;143:112471
Cellular signalling 2026 Jul;143:112471
Targeting the NR5A1-KISS1R-EMT axis with a small-molecule inhibitor suppresses lung adenocarcinoma progression and metastasis.
Wang D, Hui K, Yuan C, Lan W, Liu L, Yu Z, Li X, Shen X, Liu B, Jiang X
Cellular signalling 2026 Jul;143:112453
Cellular signalling 2026 Jul;143:112453
GLT8D2-mediated PD-L1 N-glycosylation promotes tumor immune evasion in ovarian cancer peritoneal metastasis.
Xu Y, Huang S, Chen J, Tang Z, Fu Y, Chen Z, Lin Z, Hu J, Zhang W, He S
Cancer letters 2026 Jul 10;650:218478
Cancer letters 2026 Jul 10;650:218478
piR-43452 suppresses bladder cancer progression and enhances gemcitabine sensitivity via GTSF1/PIWIL4-mediated LRP1 mRNA destabilization.
Shi Y, Sun J, Yu K, Lu D, Niu X, Li Y, Huang S, Luo J, Wang X, Ma X, Li J, Ying Y, Xie L, Liu B
Translational oncology 2026 Jan;63:102626
Translational oncology 2026 Jan;63:102626
TRIM32 promotes anoikis resistance and metastasis in NSCLC by degrading CHEK2 to enhance IL-6 secretion.
Xu J, Liu W, Chen L, Zhang J, Zhang D, Huang X, Zhang G
Cell death and differentiation 2026 Jan;33(1):126-139
Cell death and differentiation 2026 Jan;33(1):126-139
Calcitonin gene-related peptide inhibits macrophage migration and differentiation via the GTPase Rap1.
Zhang X, Huang X, Zhang Y, Xu Z, Chen Y, Sun J, Chen X, Zhang Y, Wu W, Chen Z
The Journal of biological chemistry 2026 Jan;302(1):110949
The Journal of biological chemistry 2026 Jan;302(1):110949
Downregulation of BST2 Rescues Cochlear Nerve Demyelination in Age-Related Hearing Loss via Enhancing Schwann Cell Migration.
Liu M, Li Q, Cao H, Yin H, Yang J, Liu T, Wang J, Zhao L, Wang B
Aging cell 2026 Jan;25(1):e70325
Aging cell 2026 Jan;25(1):e70325
The α5-nAChR/GINS4 axis contributed to nicotine-promoted lung adenocarcinoma progression.
Wang Z, Cai J, Yang M, Yang S, Wang J, Jia Y, Sun H, Ma X
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2026 Jan;207:115828
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2026 Jan;207:115828
Silence of circPLK1 inhibits NSCLC progression by regulating the miR-1294/SLC16A9 axis.
Li C, Yang Y, Li Q, Wang G, Tao T, Li L, Sang H
Molecular immunology 2026 Jan;189:216-225
Molecular immunology 2026 Jan;189:216-225
CypA Mediates Non-Small Cell Lung Cancer Chemoresistance by Attenuating Ferroptosis via Stabilizing SLC7A11.
Wang Z, Li A, Song Z, Liu X, Ge Y, Chen Z, Liu Y, Zhang B, Zhang H, Lan T
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(4):e11947
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(4):e11947
SIGLEC15 modulates the immunosuppressive microenvironment and suppresses malignant phenotypes in triple-negative breast cancer.
Tan Z, Xin H, Chen J, Lei M, Tu G, Tang L
Genes & diseases 2026 Jan;13(1):101799
Genes & diseases 2026 Jan;13(1):101799
NAT10-mediated ac4C modifications regulate glioblastoma progression.
Lin L, Xiong Y, Guo Y, Tu Z, Luo P, Fang Z, Zhang L, Huang K, Wu L
Cell death & disease 2026 Jan 8;17(1):181
Cell death & disease 2026 Jan 8;17(1):181
Integrating single cell- and spatial- resolved transcriptomics unravels the inter-tumor heterogeneity and immunosuppressive landscape in HBV- and Clonorchis sinensis-associated hepatocellular carcinoma.
Chen J, Lu W, Lou Y, Liu J, Liao X, Bai Y, Cheng G, Zhu G, Feng J, Liu J, Liu Z, Jia L, Zhou J, Peng T, Lu GD, Wang J
Molecular cancer 2026 Jan 5;25(1):3
Molecular cancer 2026 Jan 5;25(1):3
EIF4A3/circPTGR1/miR-4725-5p positive- feedback loop promotes colorectal cancer progression via FAK/AKT signaling pathway.
Dong Y, Ding YH, Yang X, Song XH, Lei XT, Tang YN, Zhang XE, Huang WC, Zhang K, Chen JS
Molecular cancer 2026 Jan 5;25(1):28
Molecular cancer 2026 Jan 5;25(1):28
PPIA regulates fatty acid and glutamine metabolism in lung adenocarcinoma based on multiomics prognostic model and experiment validation.
Gan Y, Wei W, Jiang B, Zhang X, Jiang L, Teng L, Xie X, Liu Y, Xie Q, Jiang L
Scientific reports 2026 Jan 5;16(1):4154
Scientific reports 2026 Jan 5;16(1):4154
SCHEMBL4796824: a multifaceted antitumor agent targeting microtubule dynamics, DNA damage, and Wnt/β-catenin signaling in ovarian cancer cells.
Ma C, Ding X, Wang B, Zhu X, Zhang Y, Ding M, Ding X, Zhou J, Zuo D, Huang Y, Ma Y, Chen G
Journal of ovarian research 2026 Jan 3;19(1):42
Journal of ovarian research 2026 Jan 3;19(1):42
CircCCDC66 promotes the progression and EMT of renal cell carcinoma via the miR-1278/HOXA13 axis.
Peng Z, Wang Q, Huang K, Chen X, Deng G, Luo J, Zhu J, Jiang K
Journal of translational medicine 2026 Jan 27;24(1):278
Journal of translational medicine 2026 Jan 27;24(1):278
SULT1E1 exerts a protective role in COPD by inhibiting the AKT pathway: an in vivo and in vitro study.
Song W, Zhang W, Wang F, Pang S, Zhou J, Li X
Scientific reports 2026 Jan 26;16(1):6238
Scientific reports 2026 Jan 26;16(1):6238
SPIB suppresses protective autophagy via the IFIT2/PINK1/Parkin axis to promote anoikis in colorectal cancer.
Deng Q, Chen Y, Chen Z, Fu Z
Cancer cell international 2026 Jan 22;26(1)
Cancer cell international 2026 Jan 22;26(1)
KIN17 facilitates the initiation and progression of renal tumor progression through the PI3K-AKT-mTOR pathway.
Wen Y, Lyu L, Zhang H, Zhang Y, Yang S, Wang Q, Song Y, Wen J
Scientific reports 2026 Jan 19;16(1):5721
Scientific reports 2026 Jan 19;16(1):5721
HOXB4 Promotes Bladder Cancer Progression in Part Through Transcriptional Activation of Smoothened.
Jin Z, Yang W, Peng Y, Ma L, Li Z, Dong J, Ji Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Jan 15;40(1):e71388
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Jan 15;40(1):e71388
Methylation-induced silencing of AZGP1 enhances prostate cancer metastasis by stimulating tumoral glycolysis.
Li L, Luo J, Zhao L, Tian L, Wang J, Cheng Y, Li X
Cellular & molecular biology letters 2026 Jan 14;31(1):5
Cellular & molecular biology letters 2026 Jan 14;31(1):5
Cuproptosis of bronchial epithelial cells triggers airway remodeling in chronic asthma.
Wang M, Liu C, Li Z, Wang Y, Li Y, Pei F
Scientific reports 2026 Jan 13;16(1):4621
Scientific reports 2026 Jan 13;16(1):4621
Linarin Suppresses the Progression of Colorectal Cancer by Inhibiting the HIF-1α/PD-L1 Axis.
Wang H, Jiang R, Luan P
Molecular carcinogenesis 2026 Feb;65(2):232-245
Molecular carcinogenesis 2026 Feb;65(2):232-245
CIAPIN1 as a Promoter of Oral Squamous Cell Carcinoma Progression.
Yang S, Sun C, Fang Z, Jin H, Li C, Zang H, Yang L, Li L, Saiyin W
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2026 Feb;55(2):209-218
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2026 Feb;55(2):209-218
COL1A1 promotes clear cell renal cell carcinoma progression through the Wnt/β-catenin signaling pathway.
Ji X, Yun Y, Zhu Z, Wu T, Ruan M, Fan Y, Zhang Q
Cellular signalling 2026 Feb;138:112259
Cellular signalling 2026 Feb;138:112259
DLGAP5 regulates malignancy and lenvatinib sensitivity of hepatocellular carcinoma through AKT/mTOR/NF-κB pathway.
He B, Deng M, Guan R, Mei J, Zou H, Tang Y, Yang Z, Zheng Z, Lin W, Li S, Guo R, Zhao R, Wei W
European journal of medical research 2026 Feb 9;
European journal of medical research 2026 Feb 9;
Interleukin-7 induces EMT to promote tumor growth and metastasis in NSCLC via Notch1/TGF-β pathway.
Shao Y, Cheng H, Ni W, Zhang A, Li C, Li X, Fu Y, Ming J
Scientific reports 2026 Feb 5;16(1)
Scientific reports 2026 Feb 5;16(1)
VAMP7 governs ferroptosis suppression and cisplatin resistance in esophageal cancer: a dual-targeting therapeutic paradigm.
Zhu J, Xie M, Dai L, Yang Z, Xue W, Jiang Z, Zhou J
Cancer cell international 2026 Feb 3;26(1)
Cancer cell international 2026 Feb 3;26(1)
Targeting TFAM K76 acetylation attenuates mitochondrial dysfunction and kidney injury in diabetic kidney disease.
Fu T, Sun S, Wang Z, Zhao F, Zhen J, Ji X, Xue F, Mu Q, Wang Y, Liu Y, Wan Q
Cardiovascular diabetology 2026 Feb 3;25(1)
Cardiovascular diabetology 2026 Feb 3;25(1)
Fibroblast Growth Factor 11 Improves Fertility by Alleviating Intrauterine Adhesionss in Rats Through Inhibition of the Transforming Growth Factor-β1/Smad Pathway.
Yin F, Fang Q, Liu X, Yu X, Rong Y, Shi D, Xu Z, Gong F, Chen M
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Feb 28;40(4):e71602
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Feb 28;40(4):e71602
TMT proteomics reveals that miR-425-5p promotes proliferation and metastasis of malignant melanoma by inhibiting SCARA5.
Ni Q, Ying D, Chang J, Yu H, Li X
Cancer cell international 2026 Feb 24;26(1)
Cancer cell international 2026 Feb 24;26(1)
Functional characterization of CASP, a CUX1 isoform, reveals its tumor-promoting role in colorectal cancer via TRIM21-mediated signaling.
Zhou B, Hu W, Dai W, Xu K, Liu L, Zheng S, Wei Q, Chen T
iScience 2026 Feb 20;29(2):114783
iScience 2026 Feb 20;29(2):114783
PARP-1 couples β-catenin/TCF4 signaling to epithelial-mesenchymal transition in endometriosis.
Zhang L, Li X, Kong L, Hou X, Li B, Zhang Y, Wang J
Scientific reports 2026 Feb 2;16(1):6940
Scientific reports 2026 Feb 2;16(1):6940
Mitochondrial uncoupling sensitizes gastric cancer cells to elesclomol-induced cuproptosis via FDX1/DLAT upregulation.
Lu Y, Li Y, Sun X, Li X, Zhao S, Fang Y, Qiu W, Luo C, Qi W
Free radical biology & medicine 2026 Feb 16;244:284-295
Free radical biology & medicine 2026 Feb 16;244:284-295
Melatonin promotes embryonic development by enhancing tryptophan metabolism and NAD + synthesis.
Yang G, Fang J, Wang H, Kong Y, Yang Q, Zhai J, Wang C, Jiang R, Sun Y, Yao G
BMC biology 2026 Feb 16;24(1)
BMC biology 2026 Feb 16;24(1)
Gingerenone A ameliorates airway inflammation and remodeling in asthma by modulating the TLR4/MyD88/NF-κB pathway.
Zhu Y, Chen L, Lin J, Chen M, Wu W, Chen Y, Xuan L
Journal of ethnopharmacology 2026 Feb 10;356:120656
Journal of ethnopharmacology 2026 Feb 10;356:120656
The circadian clock component PER2 deficiency aggravates airway epithelial remodeling through Wnt/β-catenin signaling pathway.
Zhang S, Lin J
Respiratory research 2026 Feb 10;27(1)
Respiratory research 2026 Feb 10;27(1)
Identification of mitochondrial permeability transition-related gene signatures to predict lung adenocarcinoma survival and drug response.
Liu L, Gao M, He W, Wang M, Zhou S, Wang X, Shu Y
Cell cycle (Georgetown, Tex.) 2026 Dec;25(1):1-35
Cell cycle (Georgetown, Tex.) 2026 Dec;25(1):1-35
Mitochondrial IRF3 drives pulmonary fibrosis by impairing mitophagy and triggering ferroptosis.
Jiashu Z, Jingbao L, Hua F, Meiqi S, Jing L, Mengyao W, Wei Z
Cellular signalling 2026 Aug;144:112517
Cellular signalling 2026 Aug;144:112517
INHBB promotes liver metastasis of colorectal cancer via regulation of TGF-β/Smad signaling, EMT and anoikis resistance.
Yang N, Dai D, Zhao J, Zhao H, Jiang H, Liu J, Liu F, Chen X
Tissue & cell 2026 Apr;99:103258
Tissue & cell 2026 Apr;99:103258
Angiotensin II type 1 receptor signaling promotes bladder cancer progression and its inhibition by Losartan.
Yamanaka R, Miura K, Yamasaki N, Ogata S, Nakamura M, Inaba T, Bold-Erdene A, Enkhbaatar U, Mirkatouli FB, Miura S, Hosomi N, Kobatake K, Takemoto K, Kohada Y, Tasaka R, Hatayama T, Yukihiro K, Shikuma H, Iwane K, Hinata N, Kaminuma O
Hypertension research : official journal of the Japanese Society of Hypertension 2026 Apr;49(4):1480-1494
Hypertension research : official journal of the Japanese Society of Hypertension 2026 Apr;49(4):1480-1494
Core fucosylation of NCEH1 by FUT8 promotes progression of high-grade serous ovarian cancer by driving tumor-associated macrophage M2 polarization.
Pei X, Wang F, Liu X, Lei Y, Chen Y, Liu B, Sun R, Li P, Bi J, Liu S
Oncogene 2026 Apr;45(12):1128-1144
Oncogene 2026 Apr;45(12):1128-1144
Loss of TRAIP Could Attenuate the Breast Cancer Cells Development by Regulating PLSCR4 Stabilization.
Dong Z, Chen Q, Li F, Xie W, Ma X, Ge S, Sun M, Zhao X, Zhang Z, Zhang W, Wei D, Huang S
Journal of biochemical and molecular toxicology 2026 Apr;40(4):e70825
Journal of biochemical and molecular toxicology 2026 Apr;40(4):e70825
CircRNA SLAIN1 is associated with reduced malignancy progression of glioblastoma and the M2-like polarization of tumor-associated macrophages via miR-1225-3p/NLRX1 axis.
Ai M, Li F, Huang Z, Liu C, Liao H, Huang X, Li Z, Wang B, Zhang C, Xu A, Lin J, Xu R, Yuan Y, Tian Y
International journal of biological macromolecules 2026 Apr;357:151212
International journal of biological macromolecules 2026 Apr;357:151212
FBXO32 activates the PI3K/AKT pathway by inhibiting PTEN through ubiquitination of TAL1 in hepatocellular carcinoma.
Xiong Y, Yang X, Cao T
Biochimica et biophysica acta. Molecular cell research 2026 Apr;1873(4):120125
Biochimica et biophysica acta. Molecular cell research 2026 Apr;1873(4):120125
eIF3i facilitates NELFCD translation to promote metastasis via regulating EMT and invadopodia.
Huang Q, Zhao J, Zhang Y, Zhou Y, Yang X, Chen X, Wei M, Han J, Zhang Y
British journal of cancer 2026 Apr;134(7):996-1005
British journal of cancer 2026 Apr;134(7):996-1005
Bufalin Inhibits the PI3K/AKT Pathway by Targeting GTF3C4 to Impede Breast Cancer Progression.
Guo S, Chen X, Wang H, Zhou J, Lu P, Liu J, Chai K, Zhang J, Yang S, Lu S, Gao Y, Jin Z, Tao X, Hu Z, Li Q, Wu J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(23):e07008
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(23):e07008
SLC2A3-Mediated Lactate Metabolism Promotes Lung Cancer Bone Metastasis by Modulating P53 Lactylation and Immune Evasion.
Ding Y, Tian Y, Ren W, Hu X, Li M, Liu B, Chen C, Lu Y, Li L, Yan W, Li K
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(22):e16622
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(22):e16622
Tumor-Associated Macrophage-Derived CXCL1 Promotes Endometrial Cancer Progression Through the CXCR2/NF-κB Pathway.
Xia R, Qi D, Ji B, Dai Y, Kong X
Cancer science 2026 Apr;117(4):1026-1042
Cancer science 2026 Apr;117(4):1026-1042
Novel transcription factor zinc finger 514 suppresses lung adenocarcinoma progression and enhances cisplatin sensitivity via transcriptional repression of COL1A1.
Sun S, Ma G, Cheng L, Zhang H, Fan G, Wu L, Zhang X, Xue F, Fu T, Ji X, Wan Q, Liu Y
British journal of cancer 2026 Apr 9;
British journal of cancer 2026 Apr 9;
UCHL3 Promotes Triple-Negative Breast Cancer Metastatic Potential Through Enhancing Cell Migration and Invasion.
Xu Q, Yang W, Li C, Yang M, Zhu X, Wang W, Lin Y, Gan Z, He T, Wu X, Li X
Applied biochemistry and biotechnology 2026 Apr 7;
Applied biochemistry and biotechnology 2026 Apr 7;
Zona pellucida is required for oocyte actin cortex and oocyte-somatic cell interactions during oocyte growth.
Liang S, Xiang W, Quan R, Su J, Lv C, Huang H, Xiao H
Cell death discovery 2026 Apr 20;
Cell death discovery 2026 Apr 20;
Supramolecular dynamic hydrogels loaded with bevacizumab nanoparticles promote hyaline cartilage regeneration by inhibiting angiogenesis.
Li A, Jiao Z, Liu P, Lin M, Chen J, Liang R, Huang J, Yue Y, Cao F, You H, Zeng H, Zhang K, Lin J
Acta biomaterialia 2026 Apr 20;
Acta biomaterialia 2026 Apr 20;
Gallic acid: A promising anti-non-small cell lung cancer compound targeting early growth response protein-1 for apoptosis and ferroptosis.
Li BB, Zhang JT, Jiang YY, Li X, Wang DN, Zang JM, Liu ZL, Hu FX, Zhu X, Shen CC, Zhang W, Xu F
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr 19;156:158220
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr 19;156:158220
Targeting keratin 6 A overcomes gemcitabine resistance by restoring equilibrative nucleoside transporter 1 and TAM-mediated metabolic compensation in pancreatic cancer.
Zhang J, Wang X, Zeng S, Tang B, Yang X, Xie S, Sun H, Wang R, Xia R, Li J, Wang H, Shi Z, Gu J, Wei D
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2026 Apr 17;87:101404
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2026 Apr 17;87:101404
KIAA1429 promotes clear cell renal cell carcinoma progression by regulating MYC mRNA stability.
Zhu X, Shen C, Zhang Y, Chen X, Zhang W, Zheng B, Chen Z
iScience 2026 Apr 17;29(4):115198
iScience 2026 Apr 17;29(4):115198
IL-5 promotes airway remodeling in asthma by mediating epithelial-mesenchymal transition via the AKT/NLRP3 pathway.
Zhao L, Lin Y, Dou M, Su H, Han L, Wu J, Lu Y, Bao W, Zhang M
International immunopharmacology 2026 Apr 15;175:116422
International immunopharmacology 2026 Apr 15;175:116422
TRIM29 suppresses malignant progression in lung squamous cell carcinoma by shaping an immunosuppressive tumor microenvironment.
Zhou X, Jia W, Jiang H, Zhong H, Sun J, Ma R, Wu Z, Lin Z, Lu L, Chen H
Scientific reports 2026 Apr 10;
Scientific reports 2026 Apr 10;
SEMA6A overexpression inhibited tumor growth and metastasis in colorectal cancer.
Huang C, Ma L, Zhao Q, Mi Y, Tian Y
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2025;58:e14896
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2025;58:e14896
LTF regulates glioblastoma progression and temozolomide resistance via the NF-κB signaling pathway.
Gao L, Xiao H, Lu H, Ma J, Zhu H
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2025;58:e13821
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2025;58:e13821
ZMIZ2/MCM3 Axis Participates in Triple-Negative Breast Cancer Progression.
Zou X, Sun M, Jiang X, Yu J, Li X, Nie B
Oncology research 2025;34(1):15
Oncology research 2025;34(1):15
CEP55 Promotes Acral Melanoma Progression via MAPK Pathway and Predicts Survival Following Immunotherapy.
Cao M, Zhang R, Hong A, Ye S, Qiu Z, Li D, Lin T, Wang Y
Oncology research 2025;33(9):2507-2527
Oncology research 2025;33(9):2507-2527
Terpinen-4-ol suppresses proliferation and motility of cutaneous squamous cell carcinoma cells by enhancing calpain-2 expression.
Rong D, Su Y, Zeng Z, Yang Y, Lu H, Cao YU
Oncology research 2025;33(3):605-616
Oncology research 2025;33(3):605-616
ARPC1B Promotes Clear Cell Renal Cell Carcinoma Progression via the Wnt/β-Catenin Signaling Pathway.
Peng J, Xue Y, Cai Z, Li Z, Han K, Lin X, Li Y, Zhuo Y
Oncology research 2025;33(10):3127-3154
Oncology research 2025;33(10):3127-3154
Hsa_piR_016975 Is a Novel Target of Nanotherapy that Boosts Hepatoma Progression and Sorafenib Resistance by Abating Maspin/GPX4-Mediated Ferroptosis.
Feng W, Xu J, Chen B, Liu J, Hu Y, Cao X, Qi J, Ju L, Shao J, Dong P, Chen L, Wang F
Biomaterials research 2025;29:0225
Biomaterials research 2025;29:0225
Plinabulin exerts an anti-proliferative effect via the PI3K/AKT/mTOR signaling pathways in glioblastoma.
Wang R, Cheng J, Zhang H, Luo K, Wu R, Li Y, Zhu Y, Zhang C
Iranian journal of basic medical sciences 2025;28(1):113-120
Iranian journal of basic medical sciences 2025;28(1):113-120
Smad7 ameliorate small airway remodeling in COPD by modulating epithelial-mesenchymal transition.
Liu X, Sun S, He S, Xie L
Tobacco induced diseases 2025;23
Tobacco induced diseases 2025;23
Cancer-associated Fibroblast-like Cells Promote Osteosarcoma Metastasis by Upregulation of Phosphoserine Aminotransferase 1 and Activation of the mTOR/S6K Pathway.
Feng L, Xiao G, Chen Y, Ye T, Fan L, Xie Y, Mei T, Wang L, Ge J, Ye C, Chen J
International journal of biological sciences 2025;21(9):4153-4171
International journal of biological sciences 2025;21(9):4153-4171
APOE suppresses osteosarcoma by modulating ferroptosis through the mTOR/Stat3 signaling pathway.
Cheng X, Bian C, Zhang Y, Gu H, Chen G, Wu L
Archives of medical science : AMS 2025;21(6):2647-2670
Archives of medical science : AMS 2025;21(6):2647-2670
Smad2 Cooperating with TGIF2 Contributes to EMT and Cancer Stem Cells Properties in Pancreatic Cancer via Co-Targeting SOX2.
Zu F, Chen C, Geng Q, Li H, Chan B, Luo G, Wu M, Ilmer M, Renz BW, Bentum-Ennin L, Gu H, Sheng W
International journal of biological sciences 2025;21(2):524-543
International journal of biological sciences 2025;21(2):524-543
Identification of MAPK12 as a Prognostic Biomarker for Esophageal Carcinoma Using Bioinformatics and Machine Learning.
Gu S, Yan X, Chen S, Dong Z, Li X, Ye C, Zhao C, Yuan H, Sun X, Zhao W, Zhang P
BioMed research international 2025;2025:2605071
BioMed research international 2025;2025:2605071
High SRD5A3 expression is correlated with promotion of proliferation and inhibition of apoptosis in B-cell non-Hodgkin lymphoma and suggests a poor prognosis.
Wei S, Sun J, Wen J, Yu J, Xuan Y, Huang J, Yang J, Zhang J
PloS one 2025;20(5):e0323965
PloS one 2025;20(5):e0323965
Exploring the level of metabolic reprogramming and the role of prognostic factor SF3A3 in hepatocellular carcinoma through integrated single-cell landscape analysis.
Wei W, Gan Y, Zhang X, Chen Y, Huang Z, Wang S, Xie X, Li Y, Qin P, Jiang L
PloS one 2025;20(5):e0323559
PloS one 2025;20(5):e0323559
Inhibition of HPSE/SDC-2 axis-induced epithelial-mesenchymal transition for treating IC/BPS.
Chen Z, He Y, Zhang J, Ge Q, Du T, Fan Z, Zhou J, Yang X, Shen B, Wei Z
PloS one 2025;20(5):e0321730
PloS one 2025;20(5):e0321730
IGF2BP2 contributes to thyroid cancer progression by enhancing the stability of m6A-modified CTSH mRNA.
Dong L, Chen L, Qi X, Lu Q, Li Y, Hou M
PloS one 2025;20(10):e0332061
PloS one 2025;20(10):e0332061
Exosome-Delivered circFOXP1 Upregulates Autophagy and Promotes Hepatocellular Carcinoma Progression Through Its Encoded p196 Protein Targeting the KHDRBS3/ULK1 Axis.
Zhao P, Yin C, Liu R, Shao S, Ke W, Song Z
International journal of nanomedicine 2025;20:5247-5265
International journal of nanomedicine 2025;20:5247-5265
Ginger-Derived Exosome-Like Nanoparticles Loaded With Indocyanine Green Enhances Phototherapy Efficacy for Breast Cancer.
Guo Z, Li G, Shen L, Pan J, Dou D, Gong Y, Shi W, Sun Y, Zhang Y, Ma K, Cui C, Li W, Liu Q, Zhu X
International journal of nanomedicine 2025;20:1147-1169
International journal of nanomedicine 2025;20:1147-1169
Mechanistic Exploration of Shugan Jianpi Formula for Treating Triple-Negative Breast Cancer Under Chronic Stress: A Network Pharmacology-Guided Experimental Study.
Liu F, Li L, Zhang Y, Zhang J, Tian X, Zhang D, Zhang N, Yan T, Shi S, Wu J, Jiang S
Drug design, development and therapy 2025;19:4585-4603
Drug design, development and therapy 2025;19:4585-4603
Abnormally Activated MNX1 Promotes Tumor Growth and Osimertinib Resistance and Predicts Survival in EGFR-Mutant Lung Adenocarcinoma.
Gu W, Gan J, Liu P, Lai J, Liu C, Zhang G, Shi C, Jiang Q, Qiu F
Drug design, development and therapy 2025;19:11411-11431
Drug design, development and therapy 2025;19:11411-11431
PTPRN promotes glioma cell proliferation, migration, and invasion by regulating the EMT pathway.
Wang S, Zhao X, Li M, Zhang Y, Liu B
International journal of clinical and experimental pathology 2025;18(10):509-523
International journal of clinical and experimental pathology 2025;18(10):509-523
Finerenone Ameliorates High Glucose-Induced Podocytes Epithelial-Mesenchymal Transition Through the Regulation of Krüppel-Like Factor 5 in Diabetic Nephropathy.
Shu J, Chen D, Chen W, Zhang X, Wang S, Chong N, Sun Z, Wang Q, Sun J, Xu Y
Diabetes, metabolic syndrome and obesity : targets and therapy 2025;18:637-651
Diabetes, metabolic syndrome and obesity : targets and therapy 2025;18:637-651
Ginsenoside Rg3 exerts anticancer effects in lung cancer through metabolite Histon H3.
Xiao H, Zhang Y, Zhang B, Wu J, Li X
American journal of translational research 2025;17(5):3994-4007
American journal of translational research 2025;17(5):3994-4007
As a New Tumor Suppressor Gene, PID1 Activates the AMPK-mTOR Signal to Inhibit the Progression of Bladder Cancer.
Sun L, Liu C, Cao Y, Li J, Yuan L
Research and reports in urology 2025;17:235-248
Research and reports in urology 2025;17:235-248
A novel EMT-related risk score model for Uveal melanoma based on ZNF667-AS1 and AP005121.1.
Yang F, Ren Y, Qi D, Liu X, Xie J
Journal of Cancer 2025;16(2):460-469
Journal of Cancer 2025;16(2):460-469
COL6A2 drives clear cell renal cell carcinoma progression via integrin-dependent modulation of Wnt/β-catenin signaling.
Ji X, Yun Y, Zhu Z, Wu T, Ruan M, Fan Y, Zhang Q
Journal of Cancer 2025;16(15):4426-4439
Journal of Cancer 2025;16(15):4426-4439
Comprehensive Bioinformatics Analysis and Validation of the Mechanism of Glutamic-pyruvic Transaminase 2 in Bladder Cancer.
Dong H, Li H, Chen S, Wang Q, Zhang Y, Shi H, Zuo J, Chen J, Wang J, Wang H
Journal of Cancer 2025;16(15):4357-4370
Journal of Cancer 2025;16(15):4357-4370
Hypoxia upregulate TPM4 expression to strengthen epithelial-mesenchymal transition that promotes lymph node metastasis of papillary thyroid cancer.
Li Z, Li F, Jiang X, Li Y, Jia L, Wang X, Liu Y, Jiang R, Zhao K, Pu G, Tian Y, Wang Y, He X
Journal of Cancer 2025;16(10):3216-3234
Journal of Cancer 2025;16(10):3216-3234
Cardamonin induces apoptosis of colorectal cancer cells via targeted inhibition of the JAK/STAT3/epithelial-mesenchymal transition (EMT) signaling axis.
Wu M, Chen C, Ren D, Du Z, Liu Z, Liu W
Frontiers in pharmacology 2025;16:1739201
Frontiers in pharmacology 2025;16:1739201
Prognostic modeling of glioma using epilepsy-related genes highlights PAX3 as a regulator of migration and vorinostat sensitivity.
Lin W, Lin H, Zheng Y, Wang J, Li J, Yang R, Zhang Z, Liu X, Xu X
Frontiers in neurology 2025;16:1665835
Frontiers in neurology 2025;16:1665835
circWWC3 enhances the progression of triple-negative breast cancer by interacting with vimentin to regulate the secretion of CSF2.
Wu M, Du Y, Dong Y, Zheng Y, Gu L, Tang X, Yan L, Ji H, Sang Y, Liu F
Frontiers in immunology 2025;16:1665608
Frontiers in immunology 2025;16:1665608
Thymidine kinase 1 related to Prolif-like T cells promoted GBM through regulation of cell cycle and EMT signals: a comprehensive research based on multi-omics analysis and experimental validation.
Deng W, Chang X, Shang W
Frontiers in immunology 2025;16:1655980
Frontiers in immunology 2025;16:1655980
Reciprocal activation between M1 macrophages and trophoblasts through CXCL9/STAT1/ZEB1/CCL2 axis promotes recurrent spontaneous abortion.
Yan S, Wang X, Wu Q, Ding J, Qiu H
Frontiers in immunology 2025;16:1629370
Frontiers in immunology 2025;16:1629370
CPLX1 is a novel prognostic biomarker in CRC correlating with immunotherapy resistance and ferroptosis.
Liu C, Liu Q, Lv Y, Chang T, Song S, Ding Y, Zhong J, Liu Y
Frontiers in immunology 2025;16:1589423
Frontiers in immunology 2025;16:1589423
Dissecting the multi-omics landscape of TEAD1 in hepatocellular carcinoma: cycle regulation and metastatic potential.
Huai R, Mao C, Xiong L
Frontiers in immunology 2025;16:1567969
Frontiers in immunology 2025;16:1567969
The miR-941/FOXN4/TGF-β feedback loop induces N2 polarization of neutrophils and enhances tumor progression of lung adenocarcinoma.
Zhang X, Huang X, Zhang X, Lai L, Zhu B, Lin P, Kang Z, Yin D, Tian D, Chen Z, Gao J
Frontiers in immunology 2025;16:1561081
Frontiers in immunology 2025;16:1561081
Enhancing pancreatic cancer treatment: the role of H101 oncolytic virus in irreversible electroporation.
Xi P, Zeng D, Chen M, Jiang L, Zhang Y, Qin D, Yao Z, He C
Frontiers in immunology 2025;16:1546242
Frontiers in immunology 2025;16:1546242
A comprehensive prognostic and immunological implications of Gremlin 1 in lung adenocarcinoma.
Li H, Zhou Y, Xiao J, Liu F
Frontiers in immunology 2025;16:1529195
Frontiers in immunology 2025;16:1529195
The regulatory role of the circELMOD3-associated ceRNA network in the progression and prognosis of hepatocellular carcinoma.
Li D, Liu M, Lai M, Wang L, Wei L, Wu S, Liang S, Liu S, Zeng X
Frontiers in genetics 2025;16:1521360
Frontiers in genetics 2025;16:1521360
Cyperotundone promotes chemosensitivity of breast cancer via SRSF1.
Li C, Wang L, Liu Z, Wang X, Sun L, Song X, Yu Z
Frontiers in pharmacology 2025;16:1510161
Frontiers in pharmacology 2025;16:1510161
Placental mesenchymal stem cell-derived interleukin-6 promotes neuroblastoma progression.
Liu Y, Li B, Wei H, Xu Y, Liu Y
American journal of cancer research 2025;15(8):3712-3727
American journal of cancer research 2025;15(8):3712-3727
Targeting the self-amplifying loop between ATF6 and SNAI1 to inhibit epithelial‒mesenchymal transition in fibrotic lesions.
Wu T, Liu Y, Ma J, Lu L, Wang L, He M, Hao Z, Liu X, Zhang L, Zhao C, Tao M, Zheng C, Zhou J
Theranostics 2025;15(16):7940-7955
Theranostics 2025;15(16):7940-7955
The ubiquitin ligase RCBTB2 regulates aggrephagy and inhibits prostate cancer progression by targeting GPAA1 for degradation.
Mo R, Chi N, Du J, Li X, Guo W, Li H, Wang J, Cai C, Li S, Liu C
American journal of cancer research 2025;15(10):4245-4263
American journal of cancer research 2025;15(10):4245-4263
HPV11 targeting PPARA regulates the autophagy to inhibit the occurrence and development of nasal inverted papilloma.
Zhu G, Zheng L, He W, Chen X, Huang S, Jin M, Zhang Y
Frontiers in oncology 2025;15:1743808
Frontiers in oncology 2025;15:1743808
HMCN1 as a conserved biomarker of epithelial-mesenchymal transition: a cross-cancer analysis.
Leng Y, Liu Y, Zhi L
Frontiers in oncology 2025;15:1730887
Frontiers in oncology 2025;15:1730887
Targeting the N-cadherin/β-catenin axis with MSAB reverses malignant phenotypes in blast crisis of CML.
Zhou Y, Jian S, Lu L, Li X, Qiu R
Frontiers in oncology 2025;15:1657508
Frontiers in oncology 2025;15:1657508
HOXB7 drives bladder cancer progression via H-Ras/ERK signaling: a potential therapeutic target and prognostic biomarker.
Chen X, Jiang K, Chen K, An Y, Wang Q, Chen X, Zhang P, Zhong Q, Sun F
Frontiers in oncology 2025;15:1645803
Frontiers in oncology 2025;15:1645803
Securinine, a novel alkaloid, regulates cell cycle and EMT in gastric cancer by inducing iron-dependent cell death.
Yuan W, Song H, Shi Y, Han J, Jiao S, Liang S, Xu Y, Jiang Y, Ji Y, Chen Z, Liu L, Xu A, Xu Z
Frontiers in oncology 2025;15:1599680
Frontiers in oncology 2025;15:1599680
The anti-inflammatory effects of oridonin in resisting esophageal cancer.
Peng M, Zhang X, Yang L, Liu B
Frontiers in oncology 2025;15:1585057
Frontiers in oncology 2025;15:1585057
Construction of a novel cuproptosis-related gene signature for predicting microenvironment, prognosis and therapeutic response in cervical cancer.
Cui Y, Liu Z, Zhang L, Men K, Wang M, Hu Y, Zhang Z, Liu X, Wang X
Frontiers in oncology 2025;15:1532772
Frontiers in oncology 2025;15:1532772
MiR-23b-3p ameliorates sepsis-induced acute lung injury by inhibiting SMAD3-mediated endothelial-mesenchymal transition.
Jiang L, Zhang W, He H, Tong X, Shu F, Lin J, Yang L, Huang H, Liu W, Liu T, Liu Y, Luo P, Zheng Y, Xia Z
Burns & trauma 2025;13:tkaf062
Burns & trauma 2025;13:tkaf062
L-cysteine mitigates busulfan-induced testicular injury through modulation of CBS/H(2)S axis.
Liu S, Wei B, Wei H, Xu A, Sheng L, Sun X, Dong Y, Yang H
Frontiers in cell and developmental biology 2025;13:1679330
Frontiers in cell and developmental biology 2025;13:1679330
Integrative pan-cancer analysis of UCP family and experimental validation identifies UCP2 as a potential therapeutic target for glioma.
Guo W, Chen J, Li S, Zeng X, Wu X
Frontiers in cell and developmental biology 2025;13:1662654
Frontiers in cell and developmental biology 2025;13:1662654
GNA13 promotes brain metastasis of non-small cell lung cancer and EMT through the WNT/β catenin signaling pathway.
Wu JQ, Zou HP, Fan RY, Cai J, Wei P, He MF, Xiang J
Frontiers in cell and developmental biology 2025;13:1652200
Frontiers in cell and developmental biology 2025;13:1652200
Construction of 3D Enhanced CT Radiomics-Based Model to Predict Circadian Gene Expression and Prognosis in Hepatocellular Carcinoma.
Zhao J, Zhou H, Wang C, Zhang W, Pang Y, Zheng H, Zhang L, Zhou J, Hu Z
Journal of hepatocellular carcinoma 2025;12:2989-3009
Journal of hepatocellular carcinoma 2025;12:2989-3009
Ciprofol exerts anti-tumour effects in hepatocellular carcinoma through the Raf-MEK-ERK signalling pathway.
Chen Y, Shi P, Zhou S, Yu K, Wang Y, Yao F, Zhang R, Liu X, Fang C, Tie X, Li J, Xu J, Xu J, Pan X
Translational gastroenterology and hepatology 2025;10:52
Translational gastroenterology and hepatology 2025;10:52
Mini and enhanced CRISPR activators for cancer therapies.
Huang M, Wang K, Li A, Zhu X, Zhou Z, Yang C, Bi C, Zhang X
Journal of advanced research 2025 Sep;75:151-161
Journal of advanced research 2025 Sep;75:151-161
EIF3B‑METTL3 complex promotes cell proliferation, invasion and EGFR/AKT signaling in cervical cancer.
Zhang C, Fan X, Yang J, Zhu P
Oncology reports 2025 Sep;54(3)
Oncology reports 2025 Sep;54(3)
Up-regulation of NGEF via the BRAF(V600E) /ERK/AP1 pathway enhances invasion and migration abilities of BRAF(V600E)-mutant thyroid cancer.
Fu Z, Wang Y, Wang CJ, Yu Z, Chen JQ
Biochemistry and biophysics reports 2025 Sep;43:102164
Biochemistry and biophysics reports 2025 Sep;43:102164
p62/SQSTM1 impairs immunotherapy in lung adenocarcinoma by suppressing immune infiltration and peripheral immune response.
Li H, Qin H, Xin Q, Gao J, Li S, Thomas AM, Li N, Xu L, Li M
Biochemistry and biophysics reports 2025 Sep;43:102139
Biochemistry and biophysics reports 2025 Sep;43:102139
20-Acetylsinularolide B (ASB) From Lobophytum crassum Exhibits Anticancer Activity In Vitro Through IGF1R/PI3K/AKT/mTOR Pathway.
Chang Y, Shen S, Zhang L, Zeng J, Sun J, Guo YW, Su MZ
Chemistry & biodiversity 2025 Sep;22(9):e202500114
Chemistry & biodiversity 2025 Sep;22(9):e202500114
Ganoderic acid T, a novel activator of pyruvate carboxylase, exhibits potent anti-liver cancer activity.
Lei B, Zhang M, Shi X, Feng N, Yin J, Dong R, Xie C, Zhu Y, Zhong JJ, Ni B
Metabolism: clinical and experimental 2025 Sep;170:156321
Metabolism: clinical and experimental 2025 Sep;170:156321
Shenling Tongqiao powder targets TGF-β1/Smad-Wnt/β-catenin axis to suppress epithelial-mesenchymal transition in chronic rhinosinusitis.
Liu K, Zeng H, Zhu X, Deng H, Deng W, Li S, Zhu Y, Bin J, Lu S, Wu W, Wu Q, Liao J, Hu G, Chang W, Ying Y, Wang Y, Zhu Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157065
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157065
The role of the aging process and related factor EMP1 in promoting progression of resectable pancreatic cancer.
Zhang J, Gu J, Zhang T, Xia R, Li J, Tan M, Yang Y, Xiang J, Xie B, Tang R, Li W, Wang X, Guo S, Wang H
Genes & diseases 2025 Sep;12(5):101490
Genes & diseases 2025 Sep;12(5):101490
Suppressed autophagy of thymic cells promotes apoptosis and thymic atrophy in COPD.
He S, Yang Z, Xie L
Heart & lung : the journal of critical care 2025 Sep-Oct;73:180-189
Heart & lung : the journal of critical care 2025 Sep-Oct;73:180-189
Integrator Complex Subunit 6 Regulates Biological Nature of Hepatocellular Carcinoma by Modulating Epithelial-Mesenchymal Transition.
Yonezawa S, Kanno K, Shiozaki M, Sugiyama M, Ito M
Current issues in molecular biology 2025 Sep 9;47(9)
Current issues in molecular biology 2025 Sep 9;47(9)
A Novel Nuclear-Localized Micropeptide, MP60, Promotes Hepatocellular Carcinoma Progression via the Epithelial-Mesenchymal Transition.
Li C, Hong X, Setrerrahmane S, Sun X, Zhang X, Xu H
Cancers 2025 Sep 7;17(17)
Cancers 2025 Sep 7;17(17)
LncRNA LOXL1-AS1 promotes ovarian cancer progression by enhanced BRIP1 mRNA stability.
Wan S, Su C, Ding J, Liu J, He L, Liu L, Peng Q, Ni G, Zhu W
Medical oncology (Northwood, London, England) 2025 Sep 30;42(11):504
Medical oncology (Northwood, London, England) 2025 Sep 30;42(11):504
NRF2 promotes the migration of ovarian cancer cell lines by targeting TAGLN mediated epithelial-mesenchymal transition.
Wang H, Zhang P, Cheng Q, Bao L
Journal of ovarian research 2025 Sep 30;18(1):213
Journal of ovarian research 2025 Sep 30;18(1):213
Circular RNA hsa_circ_0006522 correlates with unfavorable prognosis and promotes the proliferative, migrative, and invasive abilities of breast cancer cells.
Wang X, Zhang P, Bai Z, Meng L, Zheng Y, Sang M, Geng C
Translational cancer research 2025 Sep 30;14(9):5823-5837
Translational cancer research 2025 Sep 30;14(9):5823-5837
DTX3 inhibits cell migration, invasion, and epithelial-mesenchymal transition in colorectal cancer through the AKT signaling pathway.
Ma Z, Gong X, Zhang X
Translational cancer research 2025 Sep 30;14(9):5694-5708
Translational cancer research 2025 Sep 30;14(9):5694-5708
C1orf116 inhibits acquired resistance to EGFR inhibitors in EGFR mutant lung adenocarcinoma by suppressing the ATM/ATR pathways.
Wang F, Lu C, Yang X, Wei X, Luo W, Wu L, Yan H, Chen Z, Zhou Q
Translational lung cancer research 2025 Sep 30;14(9):3796-3810
Translational lung cancer research 2025 Sep 30;14(9):3796-3810
CHD4 drives gastric cancer metastasis via MYH9/GSK3β/β-catenin axis and WNT/EMT pathway activation.
Shi Y, Zhao Z, Zhou S, Zhou Z, Huang Z, Zhou Z, Zhang C
Cancer letters 2025 Sep 28;628:217813
Cancer letters 2025 Sep 28;628:217813
LCN2-positive alveolar type II cells promote silica-induced pulmonary fibrosis via STAT3-TGF-β1-Smad3-mediated signaling.
Xie Z, Li X, Zhang M, Cao H, Wang F, Yan R, Ye H, Mu M, Wang J, Wang F, Tao X
Toxicology and applied pharmacology 2025 Sep 27;505:117579
Toxicology and applied pharmacology 2025 Sep 27;505:117579
Overexpression of alcohol dehydrogenase 1 A inhibits the progress of triple negative breast cancer via Wnt/β-catenin signaling.
Su L, Qiao C, Luo J, Zhu B, Liu Y
Scientific reports 2025 Sep 26;15(1):32986
Scientific reports 2025 Sep 26;15(1):32986
TAIII Suppresses the Growth of T790M-Mutant Non-Small-Cell Lung Cancer by Targeting the EGFR/ERK Signaling Pathway.
Gao S, Luan Y, Yu X, Wang L, Huang X, Yang J, Liu W
Pharmaceuticals (Basel, Switzerland) 2025 Sep 24;18(10)
Pharmaceuticals (Basel, Switzerland) 2025 Sep 24;18(10)
JMJD6-driven epigenetic activation of COL4A2 reprograms glioblastoma vascularization via integrin α1β1-dependent PI3K/MAPK signaling.
Wu Y, Wu Y, Xia S, Lian H, Lou Y, Wang LJ
Acta neuropathologica communications 2025 Sep 24;13(1):194
Acta neuropathologica communications 2025 Sep 24;13(1):194
Fluzoparib disrupts Golgi apparatus to inhibit O-GlcNAcylation and nuclear translocation of β-catenin to attenuate ovarian cancer invasion and metastasis.
Peng J, Liu J, Ning M, Han W, Wang H, Wang Z, Hong L, Liu C
International immunopharmacology 2025 Sep 23;162:115158
International immunopharmacology 2025 Sep 23;162:115158
Orthosteric-allosteric dual inhibitors of PI5P4Kγ with potent antitumor activity in non-small cell lung cancer.
Xiong L, Tang 唐磊 L, Zhao W, Wang R, Cheng C, Wang D, Xu Y, Tang 汤磊 L, Fan Y
Journal of advanced research 2025 Sep 22;
Journal of advanced research 2025 Sep 22;
Biphasic Adaptations of Gastric Epithelial Cells in Chronic H. pylori Infection from Stress to Tolerance.
Zhang X, He Y, Zhang X, Liang Z, Wang W, Da Z, Lv J, Guo M, Huo X, Liu X, Lu J, Cao L, Du X, Ge Z, Chen Z, Lu X, Zhang J, Li C
International journal of molecular sciences 2025 Sep 16;26(18)
International journal of molecular sciences 2025 Sep 16;26(18)
Rictor stability mediated by USP9X regulates embryo implantation by participating in lipid metabolism of endometrium†.
Peng M, He J, Liu X, Mu X, Yin X, Liu T, Chen X, Gao R, Wang Y, Feng Q, Geng Y
Biology of reproduction 2025 Sep 15;113(3):642-656
Biology of reproduction 2025 Sep 15;113(3):642-656
DLGAP5 facilitates glioblastoma growth and tumor-associated macrophage M2 polarization.
Chen F, Luo Y, Lv F, Li H
Journal of molecular histology 2025 Sep 13;56(5):311
Journal of molecular histology 2025 Sep 13;56(5):311
CENPA-driven transcriptional activation of ECT2 enhances EGFR inhibitor resistance in lung adenocarcinoma.
Zhao M, Hang Y, Zheng H, Yang L, Yang M, Chen G, Wu G, Kong M, Wang N
Biochemical and biophysical research communications 2025 Sep 1;777:152287
Biochemical and biophysical research communications 2025 Sep 1;777:152287
Loss of MBD2 is associated with tumor growth in small intestinal neuroendocrine tumors.
Barazeghi E, Backman S, Hellman P, Norlén O, Stålberg P
Endocrine connections 2025 Sep 1;14(9)
Endocrine connections 2025 Sep 1;14(9)
Single-cell multi-omic and spatial profiling of esophageal squamous cell carcinoma reveals the immunosuppressive role of GPR116(+) pericytes in cancer metastasis.
Pei X, Liu Z, Tang L, Zhang J, He Y, Zhuang X, Song Y, Peng S, He Y, Zhao Y, Huang X, Xu Y, Li J, Peng L, Shi X, Zhang F, Liu C, He M, Dai W, Wu L, Law S, Liu J, Wang Z, Li Z, Xu W, Liu Z, Li B
Nature genetics 2025 Oct;57(10):2494-2508
Nature genetics 2025 Oct;57(10):2494-2508
LGI3 promotes the progression of TFE3-rearranged renal cell carcinoma through GEMIN6/AURKB axis.
Liu J, Feng H, Xiong Z, Cao S, Cai T, Wei W, Tao W, Zhang X, Ma X, Li X
Oncogene 2025 Oct;44(39):3729-3740
Oncogene 2025 Oct;44(39):3729-3740
USP32 stabilizes SEMA4C to promote malignant behavior of colon cancer cells.
Huang S, Cai Z, Wang Y, Zheng W, Zhan S, Huang M, Chen J
Pathology, research and practice 2025 Oct;274:156162
Pathology, research and practice 2025 Oct;274:156162
miR-29a-3p participates in the pathogenesis of spontaneous abortion by inhibiting trophoblast function targeting COL4A2/COL5A1.
Chen Q, Huang J, Wu S, Zhang L, Yang X, Sun C, Wu J, Huang X, Zhang W, Wang J
Biochemical pharmacology 2025 Oct;240:117060
Biochemical pharmacology 2025 Oct;240:117060
Phosphodiesterase 12 facilitates the growth and metastatic capabilities of gastric cancer cells by activating the TCAF2/JAK2/STAT3 axis.
Liu YJ, Song HX, Li JH, Wang XY, Nie XF, Zhang LN
Biochimica et biophysica acta. Molecular basis of disease 2025 Oct;1871(7):167973
Biochimica et biophysica acta. Molecular basis of disease 2025 Oct;1871(7):167973
KIF18B drives the malignant progression of gliomas by activating the Notch pathway.
Zhang L, Li F, Zhang L, Zhou Y, Liu Y, Liu J, Cheng Y, Shu J, Zhao H, Wei Y
Cellular signalling 2025 Oct;134:111888
Cellular signalling 2025 Oct;134:111888
Glucose Deprivation-Induced Disulfidptosis via the SLC7A11-INF2 Axis: Pan-Cancer Prognostic Exploration and Therapeutic Validation.
Song Z, Yao Q, Huang L, Cui D, Xie J, Wu L, Huang J, Zhai B, Liu D, Xu X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(39):e08556
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(39):e08556
Discovery of Natural Compound α-Hederin via Large-Scale Screening as a Targeted JAK/STAT3 Inhibitor for Ovarian Cancer Therapy.
Wang J, He P, Liu C, Chen X, Tan Y, Qu R, Zhang Y, Li Z, Yin T, Yin Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(38):e17278
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(38):e17278
Epigenetic potentiation of 5-fluorouracil by HDAC inhibitor quisinostat enhances antitumor effects in colorectal cancer.
Calibasi-Kocal G, Kurter H, Nartas ED, Ellidokuz EB, Basbinar Y
Cancer cell international 2025 Oct 8;25(1):340
Cancer cell international 2025 Oct 8;25(1):340
Oncogenic Role of SAMD4B in Breast Cancer Progression by Activating Wnt/β-Catenin Pathway.
Li JH, Wang XY, Song HX, Nie XF, Zhang LN
Biomolecules 2025 Oct 7;15(10)
Biomolecules 2025 Oct 7;15(10)
KAT2A-H3K79succ-Mediated SH2B3 Upregulation Promotes TNBC Metastasis Through Diminishing the Ubiquitin-Dependent Degradation of Vimentin.
Shi X, Hao R, Yang Z, Wang X, Lu Y, Wang X, Ji H, Ma S, Liu X, Hu J, Qi Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Oct 31;39(20):e71140
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Oct 31;39(20):e71140
miR-196a-5p promotes the proliferation, migration, and invasion of esophageal squamous cell carcinoma by targeting LIFR.
Zhang J, Liang F, Wang W, Qin Y, Hu X
Cancer cell international 2025 Oct 31;25(1):384
Cancer cell international 2025 Oct 31;25(1):384
Tanshinone IIA inhibits heat-induced growth of p53-mutant Huh-7 hepatocellular carcinoma by modulating osmotic homeostasis and glycolysis through targeting ALDH7A1.
Li H, Ju S, Wang J, Kuang D, Chen P, Zhang M, Qian R, Liang C, Han D, Duan X
Cell death discovery 2025 Oct 31;11(1):493
Cell death discovery 2025 Oct 31;11(1):493
FUT8 promotes HDM-induced glycolysis, epithelial-mesenchymal transition and inflammation in bronchial epithelial cells by inducing N-glycosylation modification of GLUT1.
Huang W, Yuan X, Lu J, Zhang S, Sun Y, Hang Y, Shen Y, Chen M, Li J, Huang J, Zhang W, Li L
Biochemical and biophysical research communications 2025 Oct 30;786:152721
Biochemical and biophysical research communications 2025 Oct 30;786:152721
RPL22L1-Myc positive feedback loop drives lung adenocarcinoma progression.
Wu Y, Zhu Y, Jiang R, Gu W, Lu L, Yao N, Du B, Lai J
Cancer cell international 2025 Oct 3;25(1):333
Cancer cell international 2025 Oct 3;25(1):333
α-hederin inhibits cervical cancer progression by inducing DNA damage-dependent cell cycle blockade and apoptosis.
Song Y, Qin H, Huang S, Wang J, Huang Y, Lin Z, Yang F, Zhang X, Wang R, Wang J
BMC cancer 2025 Oct 3;25(1):1503
BMC cancer 2025 Oct 3;25(1):1503
Fusobacterium nucleatum increases CTGF expression through TLR2-YAP signaling axis in cancer-associated fibroblasts, thereby promoting colorectal cancer progression.
Wang H, Lin B, Wang Z, Yang J, Guo X, Li W, Li B, Shi S, Zhou Y, Han R, Wei Y, Liu Y
Cancer cell international 2025 Oct 28;25(1):381
Cancer cell international 2025 Oct 28;25(1):381
The deubiquitination enzyme USP14 promotes the tumourigenesis of gastric cancer by enhancing c-MYC nuclear translocation through deubiquitination of KPNA2.
Li J, Tang H, Chang H, Du Y, Du L, Zhao E
Cell death & disease 2025 Oct 21;16(1):737
Cell death & disease 2025 Oct 21;16(1):737
A Cell-Potent Bisubstrate Inhibitor to Probe NatD Acetyltransferase Activity.
Ho YH, Seipp EK, Larndate T, Huang R
ACS chemical biology 2025 Oct 17;20(10):2512-2520
ACS chemical biology 2025 Oct 17;20(10):2512-2520
Cigarette smoke extract promotes metastasis and oxaliplatin resistance in colon adenocarcinoma through GDF15/ERBB2/AKT pathway.
Jiang W, Wang Y, Wang WJ, Zhou BC, Hu XS, Xu AM
European journal of medical research 2025 Oct 10;30(1):958
European journal of medical research 2025 Oct 10;30(1):958
TGFβ1-TNFα-regulated secretion of neutrophil chemokines is independent of epithelial-mesenchymal transition in breast tumor cells.
SenGupta S, Cohen E, Serrenho J, Ott K, Coulombe PA, Parent CA
Molecular biology of the cell 2025 Oct 1;36(10):ar122
Molecular biology of the cell 2025 Oct 1;36(10):ar122
The oncogenic role of the circ_0003997/miR-370-3p/HMGA2 axis in papillary thyroid cancer.
Ma J, Liu J, Dong C, Wang J, Tian L, Quan J
Endocrine 2025 Nov;90(2):730-744
Endocrine 2025 Nov;90(2):730-744
LAMC1 aggravates diabetic retinopathy through PI3K/AKT signaling-regulated epithelial-mesenchymal transition in retinal pigment epithelial cells.
Liu L, Gao Y, Yao S
The journal of physiological sciences : JPS 2025 Nov;75(3):100045
The journal of physiological sciences : JPS 2025 Nov;75(3):100045
Harnessing TP73‑targeted nintedanib: A novel strategy to halt triple‑negative breast cancer via p53‑PPARα/PI3K‑Akt pathway suppression.
Zou X, Li S, Huang S, Niu R, Liu G, Wang Z
International journal of oncology 2025 Nov;67(5)
International journal of oncology 2025 Nov;67(5)
SP1-Mediated upregulation of CLEC18B promotes the proliferation and metastasis of glioma through regulation of the Wnt/β-Catenin/EMT Pathway.
Liu H, Zhu B, Cui Y, Liu W, Xu Q, Lu X, Tan Z, Tian Y, Xu W
Translational oncology 2025 Nov;61:102515
Translational oncology 2025 Nov;61:102515
The dual role of interleukin-22: balancing protection and risk in pregnancy during inflammatory challenges.
Ganieva U, Bilal M, Adam A, Pena-Rasgado C, Michaels W, Rasgado-Flores H, Thees A, Luu T, Kwak-Kim J, Dambaeva S
F&S science 2025 Nov;6(4):433-446
F&S science 2025 Nov;6(4):433-446
BUB1B promotes homologous recombination‑mediated DNA damage repair in breast cancer cells through the PI3K/AKT signaling pathway.
Luo X, Wei Y, Lin H, Xiao N, Zhao W
Oncology reports 2025 Nov;54(5)
Oncology reports 2025 Nov;54(5)
METTL16 promotes progression of clear cell renal cell carcinoma via up-regulating N6-methyladenosine modification of KLK4 mRNA.
Fan B, Niu Y, Li T, Chen H, Zeng K, Li S, Ma Y
Molecular and cellular biochemistry 2025 Nov;480(11):5741-5751
Molecular and cellular biochemistry 2025 Nov;480(11):5741-5751
Integrative multi-omics analysis and experimental validation reveal centromere protein W as a potential therapeutic target and predictive biomarker in renal clear cell carcinoma.
Li J, Huang R, Tian J, Xu Z, Zhang Y, Wang X, Zhang P, Ling J, Chao L, Hu H
International journal of biological macromolecules 2025 Nov;330(Pt 3):148234
International journal of biological macromolecules 2025 Nov;330(Pt 3):148234
Galectin-9 promotes colon cancer development by polarizing macrophages toward the M2 phenotype.
Zhang J, Xu Y, Han X, Gao Y, Wei Z, Sun X
Cancer genetics 2025 Nov;298-299:141-150
Cancer genetics 2025 Nov;298-299:141-150
UBE2O-mediated ubiquitylation directs cytoplasmic CTNNA1 to promote cell-to-ECM adhesions.
Xiang D, Wu W, Shi R, Tang X, Zhang X
EMBO reports 2025 Nov;26(22):5431-5458
EMBO reports 2025 Nov;26(22):5431-5458
A Shikonin Derivative Induces Excessive Autophagy in Pancreatic Cancer Cells.
Cao Q, Zhou Y, Xiong L, Sheng M, Peng Y, Huang J, Zhang S
Chemistry & biodiversity 2025 Nov;22(11):e00721
Chemistry & biodiversity 2025 Nov;22(11):e00721
TRIB3 promotes endometrial cancer progression through interacting with E2F1 and enhancing PKM2-mediated tumor glycolysis.
Geng F, Wang Y, Cui G, Fan M
Gynecologic oncology 2025 Nov;202:41-52
Gynecologic oncology 2025 Nov;202:41-52
N-glycosylation stabilized TNFAIP6 promotes ovarian cancer metastasis by activating the PI3K-AKT signaling pathway.
Liu X, Ji D, Wen Z, Tang Q, Chen Y
Cellular signalling 2025 Nov;135:112013
Cellular signalling 2025 Nov;135:112013
The E3 ubiquitin ligase TRIM31 enhances the progression of esophageal cancer through the ubiquitination of BBOX1.
Ge L, Sun M, Xu D, Sun G
Cellular signalling 2025 Nov;135:111975
Cellular signalling 2025 Nov;135:111975
RAB26 promotes prostate cancer progression via the MAPK/ERK-TWIST1 signaling axis.
Wang H, Liang S, Du X, Zhao G, Bai Y, Li J, Xu H, Peng S, Yuan Y, Tang W
Genes & diseases 2025 Nov;12(6):101689
Genes & diseases 2025 Nov;12(6):101689
RTA-408 Enhances Radiosensitivity and Inhibited Tumor Progression via JNK Pathway in Glioblastoma.
Tsai HP, Qin H, Chong YB, Chen IH, Kuo SH, Tseng TT, Lieu AS
The Kaohsiung journal of medical sciences 2025 Nov 28;:e70142
The Kaohsiung journal of medical sciences 2025 Nov 28;:e70142
HCAR2 inhibits prostate cancer invasion and metastasis by regulating cAMP signaling pathway.
Li Y, Chen H, Huang R
Journal of investigative medicine : the official publication of the American Federation for Clinical Research 2025 Nov 28;:10815589251406272
Journal of investigative medicine : the official publication of the American Federation for Clinical Research 2025 Nov 28;:10815589251406272
GLMP promotes EGFR-TKI resistance by activating autophagy and RhoA pathway in non-small cell lung cancer.
Liang X, Xu J, Shu S, Lv W, Yin D, Miao S, Lu X, Zhang C, Liu X, Dai J, Li J, Wu W, Zhang E, Guo R
NPJ precision oncology 2025 Nov 26;9(1):391
NPJ precision oncology 2025 Nov 26;9(1):391
Protein kinase D2-mediated maintenance complex component 2 phosphorylation promotes bladder cancer progression.
Tian H, Song J, Cong J, Zhang Z, Di Y, Yan B, Nan X
Journal of translational medicine 2025 Nov 26;23(1):1357
Journal of translational medicine 2025 Nov 26;23(1):1357
Silencing Clusterin Could Attenuate the Cell Properties of HCV Core Protein-Expressing HCC Cell Line.
Han F, Cui C, Cui J, Zang S, Zhao Z, Ren W, Zhang Q, Liu L, Dong S, Fu N, Nan Y
Digestive diseases and sciences 2025 Nov 25;
Digestive diseases and sciences 2025 Nov 25;
Dynamic remodelling of epithelial plasticity in colorectal cancer from single-cell and spatially resolved perspectives.
Xu C, Pan Y, Zhang S, Lin M, Liu H, Yu Z
Journal of translational medicine 2025 Nov 24;23(1):1341
Journal of translational medicine 2025 Nov 24;23(1):1341
Keratin 80 serves as a potential biomarker in metastatic breast cancer.
Sun F, Wang D, Chen M, Lin X
Discover oncology 2025 Nov 24;16(1):2158
Discover oncology 2025 Nov 24;16(1):2158
Inhibition of FXa could be a novel therapeutic target associated with hypoxia-associated tumor behavior?
Bayrak O, Mert N, Basbinar Y, Bayrak S
Discover oncology 2025 Nov 21;16(1):2138
Discover oncology 2025 Nov 21;16(1):2138
Loss of Calpain-2 attenuates TGF-β-driven Epithelial-Mesenchymal transition and invasive behavior in A549 lung cancer cells.
Hara H, Goshima H, Hoshino D, Honda M
Biochemical and biophysical research communications 2025 Nov 19;790:152896
Biochemical and biophysical research communications 2025 Nov 19;790:152896
Ozone aging amplifies the tumor-promoting effects associated with low-dose graphene oxide exposure in bladder tumors via the integrin αV signaling pathway.
Zhu J, Yi B, Ma J, Zhang S, Zhou Z, Qi Y, Qi S
Ecotoxicology and environmental safety 2025 Nov 15;307:119458
Ecotoxicology and environmental safety 2025 Nov 15;307:119458
Antimony exposure induces bladder cancer metastasis via activation of the SUMOylation-dependent TGF-β/Smad2/3 axis.
Yi B, Zhao Z, Gao X, Zhao D, Liu X, Zhang W, Zhang Z, Zhang C
Environmental research 2025 Nov 15;285(Pt 4):122589
Environmental research 2025 Nov 15;285(Pt 4):122589
Exosomal lncRNA MIR210HG derived from hypoxic TAMs promotes the metastasis of triple negative breast cancer.
Feng L, Wang Y, Wang X, Li B, Liu Y, Zhang W, Ji J, Shao L, Guo X
International immunopharmacology 2025 Nov 14;165:115416
International immunopharmacology 2025 Nov 14;165:115416
MiR-5095 inhibits proliferation, migration, and invasion of gastric cancer cells by targeting CEACAM5.
Lin W, Cai R, Fan W, Zhang X, He F, Miao Y, Qian H, Zhao W, Zhu Y
Scientific reports 2025 Nov 14;15(1):39950
Scientific reports 2025 Nov 14;15(1):39950
A PCD-related prognostic signature and the oncogenic role of TRIM8 in osteosarcoma progression.
Zhang L, Ou X, Wang Q, Shi S
Journal of translational medicine 2025 Nov 10;23(1):1249
Journal of translational medicine 2025 Nov 10;23(1):1249
Overexpression of PLK1 Molecule Following Incomplete Thermal Ablation Promotes the Proliferation and Invasion of Residual Hepatocellular Carcinoma.
Kang T, Chen J, Wan W, Pang J, Wen R, Bai X, Li L, Pan Y, He Y, Yang H
Molecular biotechnology 2025 May;67(5):2046-2059
Molecular biotechnology 2025 May;67(5):2046-2059
ARMC10 Drives Glioblastoma Progression Through Activating Notch Pathway.
Feng B, Gao T, Chen L, Xing Y
Molecular carcinogenesis 2025 May;64(5):883-896
Molecular carcinogenesis 2025 May;64(5):883-896
KMT2A facilitates the epithelial-to-mesenchymal transition and the progression of ovarian cancer.
Zhu Y, Jiang S, Tang R, Chen H, Jia G, Zhou X, Miao J
Molecular and cellular biochemistry 2025 May;480(5):3001-3017
Molecular and cellular biochemistry 2025 May;480(5):3001-3017
PRSS23-eIF4E-c-Myc axis promotes gastric tumorigenesis and progression.
Zhou X, Guo Z, Pan Y, Yang S, Yan R
Oncogene 2025 May;44(17):1167-1181
Oncogene 2025 May;44(17):1167-1181
Lipocalin 2 Facilitates the Initial Compromise of the Blood-Brain Barrier Integrity in Chronic Cerebral Hypoperfusion.
Nie Q, Zhang L, Gu Z, Li Y, Bi X
CNS neuroscience & therapeutics 2025 May;31(5):e70438
CNS neuroscience & therapeutics 2025 May;31(5):e70438
An exploration on the involvement of the methyltransferase like 3-m(6)A‑zinc finger MYM-type containing 1 axis in the progression of liver hepatocellular carcinoma.
Chen W, Meng Y, Zhan S, Xiong F, Wang L, Yao J
International journal of biological macromolecules 2025 May;309(Pt 4):142820
International journal of biological macromolecules 2025 May;309(Pt 4):142820
HKDC1 promotes colorectal cancer progression by regulating RCOR1 expression to activate the Wnt/β-catenin pathway, enhancing proliferation, migration, and epithelial-mesenchymal transition.
Huang S, Pang Q, Zhang Y, Cao J
The Journal of biological chemistry 2025 May;301(5):108478
The Journal of biological chemistry 2025 May;301(5):108478
Kv1.3 expression on CD4 (+) T cells promotes interleukin-17A-associated airway inflammation and airway remodeling in asthma.
Sun B, Lin J
Translational research : the journal of laboratory and clinical medicine 2025 May;279:40-54
Translational research : the journal of laboratory and clinical medicine 2025 May;279:40-54
PTPRG-AS1 regulates the KITLG/KIT pathway through the ceRNA axis to promote the malignant progression of gastric cancer and the intervention effect of Compound Kushen injection on it.
Wu C, Gao Y, Jin Z, Huang Z, Wang H, Lu S, Guo S, Zhang F, Zhang J, Huang J, Tao X, Liu X, Zhang X, You L, Li Q, Wu J
Pharmacological research 2025 May;215:107743
Pharmacological research 2025 May;215:107743
CHPF2 as a novel biomarker and ponicidin as a potential therapeutic agent in hepatocellular carcinoma.
Liang Z, Ye Y, Deng Z, Lan H, Liu C, Xu Y, Fan M, Liu Z, Wu P, An L, Wang C
Pharmacological research 2025 May;215:107698
Pharmacological research 2025 May;215:107698
Circular RNA ATP9A Stimulates Non-small Cell Lung Cancer Progression via MicroRNA-582-3p/Ribosomal Protein Large P0 Axis and Activating Phosphatidylinositol 3-Kinase/Protein Kinase B Signaling Pathway.
Wang D, Huang W, Li G
Applied biochemistry and biotechnology 2025 May;197(5):3166-3183
Applied biochemistry and biotechnology 2025 May;197(5):3166-3183
EFNA2 Mediates Stiffness-Regulated Hypopharyngeal Cancer Progression.
Hu S, Liu Y, Cheng M, Xu M, Liu H, Shan Y, Ni H, Xia T, Zhang Q, Zhang Z, You B
Clinical and experimental otorhinolaryngology 2025 May;18(2):188-199
Clinical and experimental otorhinolaryngology 2025 May;18(2):188-199
Metabolic-associated fatty liver disease (MAFLD) promotes the progression of hepatocellular carcinoma by enhancing KIF20A expression.
Hu X, Chen Y, Ying H, He C, Ren Y, Tian Y, Tan Y
International immunopharmacology 2025 May 8;154:114589
International immunopharmacology 2025 May 8;154:114589
PCSK9 promotes progression of anaplastic thyroid cancer through E-cadherin endocytosis.
Zhang Y, Su W, Ji X, Yang Z, Guan Q, Pang Y, Zhong L, Wang Y, Xiang J
Cell death & disease 2025 May 6;16(1):362
Cell death & disease 2025 May 6;16(1):362
The high expression of Long noncoding RNA TEX41 promotes the proliferation, migration, and invasion of hepatocellular carcinoma.
Li Z, Xu H, Chen H, Chen L, Zang H, Qian Y
Translational cancer research 2025 May 30;14(5):3175-3185
Translational cancer research 2025 May 30;14(5):3175-3185
The lncRNA MIR22HG suppresses prostate cancer cell proliferation, migration, and epithelial-mesenchymal transition via the miR-4428/PCDH9 axis.
Li A, Sun W, Shao S, Qiu X, Hu J, Cui F
Translational cancer research 2025 May 30;14(5):3133-3148
Translational cancer research 2025 May 30;14(5):3133-3148
Enhanced mitochondrial biogenesis facilitates the development of cutaneous squamous cell carcinoma.
Wang Z, He K, Liu M, Lv W, Cheng B, Zhang G, Wang X, Zeng M, Jiao L, Han S, Zheng Y, Feng Z
Cancer letters 2025 May 28;618:217623
Cancer letters 2025 May 28;618:217623
DEC1 promotes breast cancer bone metastasis through transcriptional activation of CXCR4.
Huo Y, Chen K, Qiang Z, Lin L, Liu W, Yang J
Journal of biomedical research 2025 May 27;39(5):478-499
Journal of biomedical research 2025 May 27;39(5):478-499
GP73-dependent regulation of exosome biogenesis promotes colorectal cancer liver metastasis.
Huang L, Wei M, Li H, Yu M, Wan L, Zhao R, Gao Q, Sun L, Hou X, Mo Y, Huang Q, Zhen L, Yang X, Li J, Wang N, Zhang C, Jin H, Zhou L, Xu Y, Lin H, Zhang X, Li B, Han Y, Yuan J, Zhang R, Wu F, Zhong H, Wei C
Molecular cancer 2025 May 26;24(1):151
Molecular cancer 2025 May 26;24(1):151
Cinobufagin inhibits hepatocellular carcinoma EMT-like stemness via VEGF/VEGFR2 autocrine signaling.
Ye M, Chen S, Lu C, Wu Y, Tian J, Han A, Zhu J, Li B, Li Q
Discover oncology 2025 May 26;16(1):930
Discover oncology 2025 May 26;16(1):930
The Therapeutic Potential of Bombyx Batryticatus for Chronic Atrophic Gastritis Precancerous Lesions via the PI3K/AKT/mTOR Pathway Based on Network Pharmacology of Blood-Entering Components.
Wang X, Chang M, Feng K, Wang Q, Li B, Gao W
Pharmaceuticals (Basel, Switzerland) 2025 May 25;18(6)
Pharmaceuticals (Basel, Switzerland) 2025 May 25;18(6)
MiR-493-5p functions as a tumour suppressor in head and neck squamous cell carcinoma progression by targeting HIF-1α.
Liu J, Tian R, Chen X, Song Q, Sun C, Li D, Fang Y, Lv S, Li Y, Song X
Discover oncology 2025 May 24;16(1):899
Discover oncology 2025 May 24;16(1):899
Delivery of bone marrow mesenchymal stem cell-derived exosomes into fibroblasts attenuates intestinal fibrosis by weakening its transdifferentiation via the CCN2-TGF-β axis.
Ling F, Yang W, Yuan M, Chen Y, Li J, Wu J, Zhu L
Scientific reports 2025 May 23;15(1):18048
Scientific reports 2025 May 23;15(1):18048
miRNA-1229-5p promotes migration and invasion and suppresses apoptosis of endometrial cells via the STMN1/p38 MAPK axis in endometriosis.
Liu L, Wang L, Hao N, Du N, Li Y, Kang S
Gene 2025 May 20;950:149385
Gene 2025 May 20;950:149385
GALR1 and PENK serve as potential biomarkers in invasive non-functional pituitary neuroendocrine tumours.
Wu Z, Rao C, Xie Y, Ye Z, Zhang Y, Ma Z, Su Z, Ye Z
Gene 2025 May 20;950:149374
Gene 2025 May 20;950:149374
TMBIM1 promotes epithelial mesenchymal transition by accelerating autophagic degradation of E-cadherin in glioblastoma.
Gao L, Liu J, Li Y, Yang J, Cai J, Wang L, Ye Z, Tong S, Deng G, Chen Q, Cai Q
Scientific reports 2025 May 20;15(1):17488
Scientific reports 2025 May 20;15(1):17488
Fibrogenesis-driven tumor progression in clear cell renal cell carcinoma: prognostic, therapeutic implications and the dual role of neuropilin-1.
Wang K, Shen X, Wu J, Bi Q, Gao Z, Sun Z, Wang W
Cancer cell international 2025 May 16;25(1):179
Cancer cell international 2025 May 16;25(1):179
Exploration of the pharmacological substance basis and efficacy evaluation of fufang she-she-cao (Hedyotis diffusa formula) in repressing gastric cancer.
Chen DH, Mao PJ, Diao WJ, Lu JQ, Wu SL, Li Q
Journal of ethnopharmacology 2025 May 12;347:119711
Journal of ethnopharmacology 2025 May 12;347:119711
Knowledge-guided multi-level network modeling with experimental characterization identifies PRKCA as a novel biomarker and tumor suppressor triggering ferroptosis in prostate cancer.
Lin Y, Jia Z, Wu J, Yang H, Chen X, Wang H, Wei X, Yan W, Qi X, Huang Y
Briefings in bioinformatics 2025 May 1;26(3)
Briefings in bioinformatics 2025 May 1;26(3)
CKIP-1 inhibits M2 macrophage polarization to suppress the progression of gastric cancer by inactivating JAK/STAT3 signaling.
Xu X, Xu Z, Cai Y, Chen X, Huang C
Cell biochemistry and biophysics 2025 Mar;83(1):1289-1298
Cell biochemistry and biophysics 2025 Mar;83(1):1289-1298
FAK and p130Cas Modulate Stiffness-Mediated Early Transcription and Cellular Metabolism.
Tumenbayar BI, Pham K, Biber JC, Tutino VM, Brazzo JA 3rd, Yao P, Bae Y
Cytoskeleton (Hoboken, N.J.) 2025 Mar;82(3):197-215
Cytoskeleton (Hoboken, N.J.) 2025 Mar;82(3):197-215
Targeting ADAR1 with a small molecule for the treatment of prostate cancer.
Wang X, Li J, Zhu Y, Shen H, Ding J, Zeng T, Min W, Liang SQ, Huang L, Shi Z, Shen H, Huang F, Yuan K, Kuang W, Ji M, Sun C, Hou Y, Wang L, Chen W, Jiang Y, Hao H, Xiao Y, Yang P
Nature cancer 2025 Mar;6(3):474-492
Nature cancer 2025 Mar;6(3):474-492
Dihydroartemisinin Inhibits Epithelial-Mesenchymal Transition Progression in Medullary Thyroid Carcinoma Through the Hippo Signaling Pathway Regulated by Interleukin-6.
Li R, Zhang X, Ge Y, Zhao Z, Feng L, Li X
Cancer biotherapy & radiopharmaceuticals 2025 Mar;40(2):139-150
Cancer biotherapy & radiopharmaceuticals 2025 Mar;40(2):139-150
UBE2Q1 as a novel cancer biomarker for lung adenocarcinoma.
Jiang W, Wang Y, Zou J, Li L, Xu C
The American journal of the medical sciences 2025 Mar;369(3):359-365
The American journal of the medical sciences 2025 Mar;369(3):359-365
USP1 promotes pancreatic cancer progression and autophagy by deubiquitinating ATG14.
Li L, Fan Z, Liu M, Dong H, Li J, Li Y, Song Z, Liu Y, Zhang Z, Gu X, Zhang T
The Journal of biological chemistry 2025 Mar;301(3):108190
The Journal of biological chemistry 2025 Mar;301(3):108190
The MCM6-c-Myc positive feedback loop mediates bladder cancer progression and cisplatin resistance.
Wang J, Li X, Zhao L, Fan X, Cao J, Wang S, Li K, Wang H, Zhang Y, Wang H, Xu C, Ding L, Che T, Chen S, Yang L
International journal of biological macromolecules 2025 Mar;296:139777
International journal of biological macromolecules 2025 Mar;296:139777
High MICAL-L2 promotes cancer progression and drug resistance in renal clear cell carcinoma cells through stabilization of ACTN4 following vimentin expression.
Zhao W, Qi C, Mao Y, Ye F, Xia T, Zhao M, Min P, Zhang Y, Du J
Biochimica et biophysica acta. Molecular basis of disease 2025 Mar;1871(3):167628
Biochimica et biophysica acta. Molecular basis of disease 2025 Mar;1871(3):167628
circTUBD1-hnRNPK Regulates the Proliferation and Migration of LSCC by Targeting CCAR1.
Xu Y, Qiu S, Shen Z, Chen J
Cancer medicine 2025 Mar;14(6):e70834
Cancer medicine 2025 Mar;14(6):e70834
Melanoma Cell Adhesion Molecule Plays a Pivotal Role in Proliferation, Migration, Tumor Immune Microenvironment, and Immunotherapy in Colorectal Cancer.
Zhou J, Liu J, Yu Y, Nie H, Hong Y, Ning Y, Yang C, Lai J, Wang H, Tang X, Wang F, Zhao Q
Cancer medicine 2025 Mar;14(5):e70740
Cancer medicine 2025 Mar;14(5):e70740
circFOXK2 Stabilizes STMN1 mRNA via PABPC1 to Promote the Progression of NSCLC.
Chen W, Zhao W, Wu X, Fang T, Chen Z, Chen Z, Su W, Zhao X, Hu Y, Xu Y, Fang S, Zhou C
Cancer medicine 2025 Mar;14(5):e70729
Cancer medicine 2025 Mar;14(5):e70729
Procyanidin B2 alleviates damage to mouse testicular tissue after freezing by inhibiting oxidative stress and apoptosis.
Cao G, Li C, Zhang J, Deng L, Li R, Xu C
Cryobiology 2025 Mar;118:105196
Cryobiology 2025 Mar;118:105196
Melatonin affects trophoblast epithelial-to-mesenchymal transition and oxidative damage resistance by modulating GDF15 expression to promote embryo implantation.
Yang G, Yao G, Wang H, Jiang R, Fang J, Hu J, Kong Y, Jin H, Song W, Wu Z, Huang X, Sun Y
Communications biology 2025 Mar 8;8(1):396
Communications biology 2025 Mar 8;8(1):396
HNRNPC promotes progression of non-small cell lung cancer by maintaining TFAP2A mRNA stability.
Liao M, Li C, Yang R, Li J, Wu K, Zhang J, Zhu Q, Shi Y, Zhang X
Cancer cell international 2025 Mar 8;25(1):85
Cancer cell international 2025 Mar 8;25(1):85
Parvimonas micra promotes oral squamous cell carcinoma metastasis through TmpC-CKAP4 axis.
Qi H, Gao H, Li M, Sun T, Gu X, Wei L, Zhi M, Li Z, Fu D, Liu Y, Wei Z, Dou Y, Feng Q
Nature communications 2025 Mar 7;16(1):2305
Nature communications 2025 Mar 7;16(1):2305
Single-cell and spatial transcriptome profiling reveal CTHRC1+ fibroblasts promote EMT through WNT5A signaling in colorectal cancer.
Lu Y, Chen Y, Wang Z, Shen H, Xu L, Huang C, Tong Y, Shao Y, Zhang H, Fu Z
Journal of translational medicine 2025 Mar 6;23(1):282
Journal of translational medicine 2025 Mar 6;23(1):282
NEAT1 promotes the perineural invasion of pancreatic cancer via the E2F1/GDNF axis.
Gu J, Wang Q, Mo J, Qin T, Qian W, Duan W, Han L, Wang Z, Ma Q, Ma J
Cancer letters 2025 Mar 31;613:217497
Cancer letters 2025 Mar 31;613:217497
Cyanidin-3-glucoside upregulated NDRG2 through the PI3K/AKT pathway to alleviate EMT and ECM in renal fibrosis.
Lu Q, Liu J, Xiong Y, Jian J, Wang J, Chen Z, Wan S, Liu X, Wang L
Scientific reports 2025 Mar 28;15(1):10695
Scientific reports 2025 Mar 28;15(1):10695
c-Jun promotes neuroblastoma cell differentiation by inhibiting APC formation via CDC16 and reduces neuroblastoma malignancy.
Wang Y, Huang J, Song Z, Zhang S, Guo H, Leng Q, Fang N, Ji S, Yang J
Biology direct 2025 Mar 27;20(1):37
Biology direct 2025 Mar 27;20(1):37
miR-378d suppresses gastric cancer metastasis by targeting METTL4 to inhibit epithelial-mesenchymal transition.
Xing D, Bao J, He J, Gao H, Xue W, Chen J, Li J
Journal of molecular histology 2025 Mar 22;56(2):116
Journal of molecular histology 2025 Mar 22;56(2):116
Protocol for generating brain metastatic tumor cells through repeated intracardiac injections in mice.
Wang L, Chen X, Dong C, Yin S, Liang L, Zhou A
STAR protocols 2025 Mar 21;6(1):103531
STAR protocols 2025 Mar 21;6(1):103531
YWHAG promotes the progression of lung adenocarcinoma through the JAK2/STAT3 pathway.
Zheng H, Tang Y, Zang H, Luo J, Zhou H, Zou Y, Peng J, Fan S
Cancer cell international 2025 Mar 21;25(1):112
Cancer cell international 2025 Mar 21;25(1):112
Single-molecule m(6)A detection empowered by endogenous labeling unveils complexities across RNA isoforms.
Guo W, Ren Z, Huang X, Liu J, Shao J, Ma X, Wei C, Cun Y, He J, Zhang J, Wu Z, Guo Y, Zhang Z, Feng Z, He J, Wang J
Molecular cell 2025 Mar 20;85(6):1233-1246.e7
Molecular cell 2025 Mar 20;85(6):1233-1246.e7
Starvation-induced HBP metabolic reprogramming and STAM2 O-GlcNAcylation facilitate bladder cancer metastasis.
Feng Z, Mei Y, Chen H, Li L, Jin T, Li X, Gou X, Chen Y
Scientific reports 2025 Mar 12;15(1):8480
Scientific reports 2025 Mar 12;15(1):8480
Oxidative Stress Regulates CDH3 Expression in Lung Cancer Cells via OGG1-Mediated SP1 Binding.
Ma Y, Guo J, Xu S, Hou Y, Pan F, Guo Z
Antioxidants (Basel, Switzerland) 2025 Mar 11;14(3)
Antioxidants (Basel, Switzerland) 2025 Mar 11;14(3)
CENPF interaction with PLA2G4A promotes glioma growth by modulating mTORC1 and NF-κB pathways.
Li J, Zhang M, Sun Q, Li X, Du F, Cheng Y, Li S, Zhang J
Cancer cell international 2025 Mar 1;25(1):73
Cancer cell international 2025 Mar 1;25(1):73
miR-135b-5p/PDE3B Axis Regulates Gemcitabine Resistance in Pancreatic Cancer Through Epithelial-Mesenchymal Transition.
Fu Y, Chen L, Lv N, Wang J, Yu S, Fang Q, Xin W
Molecular carcinogenesis 2025 Jun;64(6):1119-1130
Molecular carcinogenesis 2025 Jun;64(6):1119-1130
Granzyme B Promotes Proliferation, Migration and EMT Process in Gastric Cancer.
Lu Z, Huang X, Shen Q, Chen E, Feng Y
Biochemical genetics 2025 Jun;63(3):2513-2529
Biochemical genetics 2025 Jun;63(3):2513-2529
H3K18 lactylation-mediated SIX1 upregulation contributes to silica-induced epithelial-mesenchymal transition in airway epithelial cells.
Liu S, He Y, Jin L, Shi S, Zhang J, Xie W, Yang M, Zhang Q, Kong H
Toxicology 2025 Jun;514:154109
Toxicology 2025 Jun;514:154109
LncRNA MKLN1-AS promotes glioma tumorigenesis and growth via activating the Hippo pathway through miR-126-5p/TEAD1 axis.
Chen S, Tu S, Huang Y, Lin H, Wang Y, Dai X
Naunyn-Schmiedeberg's archives of pharmacology 2025 Jun;398(6):6787-6799
Naunyn-Schmiedeberg's archives of pharmacology 2025 Jun;398(6):6787-6799
GJB2 as a novel prognostic biomarker associated with immune infiltration and cuproptosis in ovarian cancer.
Lei H, Guo K, Shu G, Wang M, Li Y, Tan Z, Pan Q, Yin G
Apoptosis : an international journal on programmed cell death 2025 Jun;30(5-6):1589-1613
Apoptosis : an international journal on programmed cell death 2025 Jun;30(5-6):1589-1613
LncRNA SNHG14 Regulated by ZNF460 Promotes Gastric Cancer Progression and Metastasis by Targeting the miR-206/FNDC3A Axis.
Liu B, Lu T, Zhang G, Dong X, Yu M, Cai H
Journal of cellular and molecular medicine 2025 Jun;29(11):e70652
Journal of cellular and molecular medicine 2025 Jun;29(11):e70652
Charge-reversed small extracellular vesicles from human adipose-derived mesenchymal stromal cells attenuate renal fibrosis postacute kidney injury by inhibiting epithelial-mesenchymal transition progression in SD rat model.
Ping W, Xu X, Jiang Y, Yang R, Xu L
Cytotherapy 2025 Jun;27(6):753-765
Cytotherapy 2025 Jun;27(6):753-765
Rotenone adaptation promotes migration and invasion of p53-wild-type colon cancer through lipid metabolism.
Shi Y, Cao Z, Ge L, Lei L, Tao D, Zhong J, Xu D, Geng T, Li X, Li Z, Xing S, Wu X, Wang Z, Li L
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2025 Jun;27(6):2557-2567
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2025 Jun;27(6):2557-2567
MBD2 promotes epithelial-to-mesenchymal transition (EMT) and ARDS-related pulmonary fibrosis by modulating FZD2.
Zhou Y, Yang G, Liu J, Yao S, Jia J, Tang X, Gong X, Wan F, Wu R, Zhao Z, Liang H, Liu L, Liu Q, Xie S, Long X, Xiang X, Wang G, Xiao B
Biochimica et biophysica acta. Molecular basis of disease 2025 Jun;1871(5):167798
Biochimica et biophysica acta. Molecular basis of disease 2025 Jun;1871(5):167798
Distinct CTC Specific RNA Profile Enables NSCLC Early Detection and Dynamic Monitoring of Advanced NSCLC.
Wang X, Ding P, Xu W, Qiu L, Ren J, Fei Y, Wang Z, Li C, Xing Y, Shen M, Zhu Y, Guo Y, Sun N, Pei R, Shi M
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(23):e2417849
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(23):e2417849
Oleanolic Acid Restores Drug Sensitivity in Sorafenib-resistant Hepatocellular Carcinoma: Evidence from In Vitro and In Vivo Studies.
Li T, Shen X, Zhang T, Ren J, Wang W, Wang D, Zhang P
Journal of clinical and translational hepatology 2025 Jun 28;13(6):469-483
Journal of clinical and translational hepatology 2025 Jun 28;13(6):469-483
Dexmedetomidine promotes colorectal cancer progression mediated by gamma-aminobutyric acid signaling.
Dong J, Wu Y, Che J, He Z, Zhang J
Cancer & metabolism 2025 Jun 23;13(1):33
Cancer & metabolism 2025 Jun 23;13(1):33
IGFBP2 Modulates Trophoblast Function and Epithelial-Mesenchymal Transition in Preeclampsia via the PI3K/AKT Signaling Pathway.
Meng S, Qin Y, Lyu C, Wang S
Current issues in molecular biology 2025 Jun 20;47(7)
Current issues in molecular biology 2025 Jun 20;47(7)
Fibulin-4 is highly expressed in metastatic breast cancer and can serve as a target of peptide-based imaging probes and experimental therapeutics.
Daquinag AC, AghaAmiri S, Farmer SM, Zhang S, Ghosh SC, Vargas SH, Ramesh AK, An Z, Azhdarinia A, Kolonin MG
bioRxiv : the preprint server for biology 2025 Jun 19;
bioRxiv : the preprint server for biology 2025 Jun 19;
DDX5 super-enhancer promotes vasculogenic mimicry formation and metastasis in nasopharyngeal carcinoma by enhancing ADAM10 transcription.
Xia T, Yin H, Zhu Q, Zhang K, Xie H, Shan Y, Zhang S, Zhu R, Li K, Miao M, Lu Y, Wang Z, Zhao J, You Y, You B
Cell reports. Medicine 2025 Jun 17;6(6):102146
Cell reports. Medicine 2025 Jun 17;6(6):102146
Airway microbiota associated D-phenylalanine promotes non-small cell lung cancer metastasis through epithelial mesenchymal transition.
Gao L, Liao H, Chen Y, Ye C, Huang L, Xu M, Du J, Zhang J, Huang D, Cai S, Dong H
Journal of translational medicine 2025 Jun 17;23(1):673
Journal of translational medicine 2025 Jun 17;23(1):673
Nobiletin from Citrus reticulata Blanco alleviates pulmonary fibrosis through inhibiting the PI3K/AKT pathway and epithelial-mesenchymal transition.
Yu S, Liu K, Zhou F, Yang X, Zhang J, Yu K, Zhu Y, Qin L, Peng T, Zhang C, He Y
Journal of ethnopharmacology 2025 Jun 12;349:119965
Journal of ethnopharmacology 2025 Jun 12;349:119965
Role of the USP7/FOXO3A axis in environmentally relevant doses of arsenic-induced lung carcinogenesis: Insights from bioinformatics analysis and model of human epithelial cell malignant transformation.
Chen X, Wang Y, Liu Z, He Y, Gao H, Guan X, Chen L, Chen S, Xing X, Chen W, Li D, Wang Q
Ecotoxicology and environmental safety 2025 Jun 1;297:118224
Ecotoxicology and environmental safety 2025 Jun 1;297:118224
Curcumenol inhibits malignant progression and promotes ferroptosis via the SLC7A11/NF‑κB/TGF‑β pathway in triple‑negative breast cancer.
Li F, Qi Q, Qiao Y, Huang Y, Lu Y, Gu K, Liu H, Gao C, Liu S, Wu H
International journal of molecular medicine 2025 Jul;56(1)
International journal of molecular medicine 2025 Jul;56(1)
PUS7 promotes the progression of pancreatic cancer by interacting ANLN to activate MYC pathway.
Jiang Y, Cheng Q, Zhang Y, Zhong J
Molecular and cellular biochemistry 2025 Jul;480(7):4401-4415
Molecular and cellular biochemistry 2025 Jul;480(7):4401-4415
TCF7 functions as a prognostic biomarker in bladder cancer by strengthening EMT and stemness associated with TGF-β/SMAD3 signaling.
Zhang C, Cai H, Ye M, Wang L, Liu W, Huang Q, Peng X, Mao G, Zhang Q, Mei Y
Molecular and cellular biochemistry 2025 Jul;480(7):4135-4148
Molecular and cellular biochemistry 2025 Jul;480(7):4135-4148
CYP2A6 suppresses hepatocellular carcinoma via inhibiting SRC/Wnt/β-Catenin pathway.
Liu YF, Feng LY, Zhang WY, Zhang X, Shao LJ, Zhao XM, Ji JB, Guo XL
Acta pharmacologica Sinica 2025 Jul;46(7):2029-2040
Acta pharmacologica Sinica 2025 Jul;46(7):2029-2040
HucMSC-Ex alleviates inflammatory bowel disease by regulating O-GlcNAcylation modification of RACK1 in intestinal epithelial cells.
Liu Z, Yuan J, Din MA, Tian Y, Mao F
Colloids and surfaces. B, Biointerfaces 2025 Jul;251:114606
Colloids and surfaces. B, Biointerfaces 2025 Jul;251:114606
Wenxia Changfu Formula inhibits NSCLC metastasis by halting TAMs-induced epithelial-mesenchymal transition via antagonisticallymodulating CCL18.
Bi Q, Wang M, Luo L, Zhang B, Lv S, Wang Z, Ji X
Chinese journal of natural medicines 2025 Jul;23(7):838-847
Chinese journal of natural medicines 2025 Jul;23(7):838-847
Identification of the Oncogenic Role of MSH2 in the Stemness and Progression of Glioma Through Regulating Wnt Signaling Pathway.
Liu J, Chen J, Jiang L
Cancer medicine 2025 Jul;14(13):e70993
Cancer medicine 2025 Jul;14(13):e70993
Neoadjuvant Chemotherapy With Cisplatin Up-Regulates GSDMD to Enhance Oral Squamous Cell Carcinoma Metastasis Through MMP14-Mediated EMT Activation.
Huang Z, Jiang Q, Zhang Q, Lu N, Rui X, Chen R, Wang Y, Wang Y, Xu X, Huang Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jul;12(25):e2501149
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jul;12(25):e2501149
M6A-Methylated circRAPGEF5 drives lung adenocarcinoma progression and metastasis via IGF2BP2/NUP160-mediated autophagy suppression.
Ling L, Hu T, Zhou C, Dai Y, Hu L, Chen Y, Hu Z, Huang K, Chen J, Wang Y
Molecular cancer 2025 Jul 8;24(1):192
Molecular cancer 2025 Jul 8;24(1):192
P300-dependent acetylation of the FOXQ1 complex activates super-enhancers to promote colorectal cancer proliferation and metastasis.
Yang WD, Zhang ZH, Zhao MY, Shao K, Ma YF, Shen Q, Lu MR, Shao ZY, Xu JY, Cao MH, Meng S, Chu SF, Yong HM, Ding J, Bai J
Communications biology 2025 Jul 7;8(1):1016
Communications biology 2025 Jul 7;8(1):1016
RhoJ promotes the progression of clear cell renal cell carcinoma via the TNF-α/NF-κB axis.
Feng J, Zheng B, Wang J, Xu Q, Ouyang Q, Li H, Jia T, Wang Y, Cai T, Feng Y, Zhang X, Li X, Ma X
Translational andrology and urology 2025 Jul 30;14(7):1849-1864
Translational andrology and urology 2025 Jul 30;14(7):1849-1864
Effects of PELP1 on proliferation, metastasis and angiogenesis of epithelial ovarian cancer.
Xie L, Sun C, Mao Y, Huang X, Yang X, Huang J, Zhang Y, Li C, Yang W, Zhang W, Wang J
Medical oncology (Northwood, London, England) 2025 Jul 26;42(9):379
Medical oncology (Northwood, London, England) 2025 Jul 26;42(9):379
GPX3 promotes cisplatin resistance in TNBC by manipulating ROS-TGFB1-ZEB2.
Hu Q, Chen Q, Yang W, Ren A, Tan J, Huang T
Cell communication and signaling : CCS 2025 Jul 25;23(1):355
Cell communication and signaling : CCS 2025 Jul 25;23(1):355
Terrestrosin D promotes autophagy and apoptosis of breast cancer cells through PSMD1-dependent activation of P53 pathway.
Jia LL, Wu CJ, Ye PW, Zhang Q, Liu H, Li TP, Hu XL
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156883
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156883
Curzerene suppresses epithelial-mesenchymal transition in gastric precancerous lesion cells through targeted regulation of YAP via the long non-coding RNA AFAP1-AS1.
Zhou X, Zhang C, Shen W, Zhuang R, Liu S, Liu J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156879
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156879
Design, Synthesis, and Activity Evaluation of Novel Nucleosides as ADAR1 Inhibitor for the Treatment of Prostate Cancer.
Zhu Y, Shen H, Ding J, Wang M, Ji J, Hou Y, Cai Z, Li J, Chen W, Kuang W, Wang L, Min W, Yang P, Wang X
Journal of medicinal chemistry 2025 Jul 24;68(14):14495-14513
Journal of medicinal chemistry 2025 Jul 24;68(14):14495-14513
DSS1 inhibits autophagy to activate epithelial-mesenchymal transition in a pro-metastatic niche of renal cell carcinoma.
Chen X, Liu Q, Wu J, Zhou P, Zhao M, Song J
Nature communications 2025 Jul 23;16(1):6769
Nature communications 2025 Jul 23;16(1):6769
Molecular function validation and prognostic value analysis of the cuproptosis-related gene ferredoxin 1 in papillary thyroid carcinoma.
He S, Peng W, Hu X, Chen Y
Scientific reports 2025 Jul 23;15(1):26845
Scientific reports 2025 Jul 23;15(1):26845
P4HA2 promotes the progression of papillary thyroid cancer by enhancing degradation of IκBα to activate NF-κB signaling pathway.
Li R, Zhao M, Sun M, Wu Y, Miao C, Fangyu L, Wu M, Shi X, Lu J, Yue X
Cancer cell international 2025 Jul 2;25(1):249
Cancer cell international 2025 Jul 2;25(1):249
Hypertension-related genes STOM, MEF2C promote proliferation and migration of clear cell renal cell carcinoma.
Huang Z, Wang N, Dong Y, Wang X, He M, Li M, Tang X, Fu D, Xue L, Chong T
Experimental cell research 2025 Jul 15;450(2):114692
Experimental cell research 2025 Jul 15;450(2):114692
"TFEB-HNRNPA2B1": A positive feedback loop facilitating metastasis in hepatocellular carcinoma cells.
Yan X, Wu Y, Dai X, Wen H, Xiang W, Yang M, Zhang Y, Xiang L, Lu L, Chen A, He F, Lian J
Experimental cell research 2025 Jul 15;450(2):114669
Experimental cell research 2025 Jul 15;450(2):114669
Secreted phosphoprotein 1 promotes the activation of keloid fibroblasts via the CD44/TGF-β1/Smad pathway.
Tu Y, Xiong Y, Liu O, Peng Y
Experimental cell research 2025 Jul 15;450(2):114658
Experimental cell research 2025 Jul 15;450(2):114658
Elevated SGO2 expression in lung adenocarcinoma promotes migration and invasion via MAD2 and correlates with poor prognosis.
Sun M, Zhou W, Wei G, Lv M, Sun Y, Zhao H, Zhu C
Scientific reports 2025 Jul 15;15(1):25642
Scientific reports 2025 Jul 15;15(1):25642
FOXL2 Knockdown Inhibits the Progression of Endometriosis.
Zhang B, Li SJ, Yuan H, Cong SS, Zhao SJ, Yang XJ
American journal of reproductive immunology (New York, N.Y. : 1989) 2025 Jan;93(1):e70043
American journal of reproductive immunology (New York, N.Y. : 1989) 2025 Jan;93(1):e70043
EIF4A3-Induced Circ_0059914 Promoted Angiogenesis and EMT of Glioma via the miR-1249/VEGFA Pathway.
Yu W, Chen D, Ma L, Lin Y, Zheng J, Li X
Molecular neurobiology 2025 Jan;62(1):973-987
Molecular neurobiology 2025 Jan;62(1):973-987
EML4-ALK G1202R and EML4-ALK L1196M mutations induce crizotinib resistance in non-small cell lung cancer cells through activating epithelial-mesenchymal transition mediated by MDM2/MEK/ERK signal axis.
Yang Y, Yang H, Gao Y, Yang Q, Zhu X, Miao Q, Xu X, Li Z, Zuo D
Cell biology international 2025 Jan;49(1):55-67
Cell biology international 2025 Jan;49(1):55-67
TMEM252 inhibits epithelial-mesenchymal transition and progression in papillary thyroid carcinoma by regulating Notch1 expression.
Zhang S, Xie R, Wang L, Fu G, Zhang C, Zhang Y, Yu J
Head & neck 2025 Jan;47(1):324-338
Head & neck 2025 Jan;47(1):324-338
ATF1 regulates MAL2 expression through inhibition of miR-630 to mediate the EMT process that promotes cervical cancer cell development and metastasis.
Cao Y, Peng Y, Tang Y
Journal of gynecologic oncology 2025 Jan;36(1):e11
Journal of gynecologic oncology 2025 Jan;36(1):e11
4‑Methoxydalbergione inhibits the tumorigenesis and metastasis of lung cancer through promoting ferroptosis via the DNMT1/system Xc‑/GPX4 pathway.
Fan J, Lin H, Luo J, Chen L
Molecular medicine reports 2025 Jan;31(1)
Molecular medicine reports 2025 Jan;31(1)
NKD2 as a Mediator of IFIX Antioncogene-Induced Wnt Signalling and Epithelial-Mesenchymal Transition in Human OSCC.
Wang S, Fan H, Bai J
Journal of cellular and molecular medicine 2025 Jan;29(2):e70342
Journal of cellular and molecular medicine 2025 Jan;29(2):e70342
NAP1L5 promotes epithelial-mesenchymal transition by regulating PEG10 expression in acute myeloid leukaemia.
Wu H, Luo H, Wang M, Du Y, Li J
Leukemia research 2025 Jan;148:107623
Leukemia research 2025 Jan;148:107623
Cyclovirobuxine D inhibits triple-negative breast cancer via YAP/TAZ suppression and activation of the FOXO3a/PINK1-Parkin pathway-induced mitophagy.
Wang ZQ, Wu ZX, Chen JW, Li HF, Wu HD, Bao JX, Cheng Y, Dai YW, Wang OC, Dai XX
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156287
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156287
Mechanistic insights into the treatment of pulmonary fibrosis with bioactive components from traditional chinese medicine via matrix stiffness-mediated EMT.
Li K, Liu H, Li M, Sun M, Peng X, Wu Y, Tian Y, Liu X, Li J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156266
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156266
Modified Zuojin pill alleviates gastric precancerous lesions by inhibiting glycolysis through the HIF-1α pathway.
Liu S, Ji H, Zhang T, Huang J, Yin X, Zhang J, Wang P, Wang F, Tang X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156255
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156255
TIFA enhances glycolysis through E2F1 and promotes the progression of glioma.
Liu Z, He M, Yu Z, Ma L, Wang X, Ning F
Cellular signalling 2025 Jan;125:111498
Cellular signalling 2025 Jan;125:111498
Hirudo extract ameliorates proliferative vitreoretinopathy by promoting autophagy and attenuating the THBS2/PI3K/Akt pathway.
Huang H, Huang Q, Wang J, Wang W, Zheng Y
Scientific reports 2025 Jan 8;15(1):1287
Scientific reports 2025 Jan 8;15(1):1287
Estrogen Receptor β Activation Mitigates Colitis-associated Intestinal Fibrosis via Inhibition of TGF-β/Smad and TLR4/MyD88/NF-κB Signaling Pathways.
Ling F, Chen Y, Li J, Xu M, Song G, Tu L, Wang H, Li S, Zhu L
Inflammatory bowel diseases 2025 Jan 6;31(1):11-27
Inflammatory bowel diseases 2025 Jan 6;31(1):11-27
MYBL2 promotes proliferation of clear cell renal cell carcinoma by regulating TOP2A and activating AKT/mTOR signaling pathway.
Huang Y, Xi X, Ye Z, Zhang C, Jiang Y, Yu F, Huang G
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jan 31;39(2):e70330
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jan 31;39(2):e70330
Pharmacological effects and mechanisms of danlong oral liquid in asthma airway remodeling: Insights from serum medicinal chemistry, network pharmacology, and experimental validation.
Liu B, Xiang M, Zhou M, Li C, Xin H, Zhang S, Lin J
Journal of ethnopharmacology 2025 Jan 31;340:119259
Journal of ethnopharmacology 2025 Jan 31;340:119259
Formin protein DAAM1 positively regulates PD-L1 expression via mediating the JAK1/STAT1 axis in pancreatic cancer.
Xu R, Wan M, Pan J, Mei J, Zhou J, Shen Y, Yang J, Zhu Y, Sun J
Cancer cell international 2025 Jan 29;25(1):28
Cancer cell international 2025 Jan 29;25(1):28
UBE2J1 is identified as a novel plasma cell-related gene involved in the prognosis of high-grade serous ovarian cancer.
Tian Y, Dong R, Guan Y, Wang Y, Zhao W, Zhang J, Kang S
Journal of translational medicine 2025 Jan 28;23(1):129
Journal of translational medicine 2025 Jan 28;23(1):129
DRAM1 enhances the proliferation and metastasis of gastric cancer through the PI3K/AKT/mTOR signaling pathway and energy metabolism.
Wu X, Li Y, Wang W, Xu J, Zhao B, Sun W, Ge D, Xiong L, Dou X, Zou X, Wang L, Chen M
Scientific reports 2025 Jan 28;15(1):3542
Scientific reports 2025 Jan 28;15(1):3542
Perilipin2-dependent lipid droplets accumulation promotes metastasis of oral squamous cell carcinoma via epithelial-mesenchymal transition.
Zhang J, Peng J, Wang S, Wang L, Sun Y, Xia J, Cheng B, Hu Q
Cell death discovery 2025 Jan 28;11(1):30
Cell death discovery 2025 Jan 28;11(1):30
Hypoxia and lipid metabolism related genes drive proliferation migration and immune infiltration mechanisms in colorectal cancer subtyping.
Huang S, Wang H, Cao J, Pang Q
Scientific reports 2025 Jan 18;15(1):2394
Scientific reports 2025 Jan 18;15(1):2394
Hypoxia-induced circPLOD2a/b promotes the aggressiveness of glioblastoma by suppressing XIRP1 through binding to HuR.
Yu A, Wang Y, Duan C, Qin J, Liao M, Zhu H, Lei J, Liu J, Yang Z, Yu L, Gui H, Xin J, Tao W, Bao W, Dong Z
Communications biology 2025 Jan 17;8(1):71
Communications biology 2025 Jan 17;8(1):71
MicroRNA-32-5p promotes the proliferation and metastasis of gastric cancer cells.
Sun C, Huang LG, Leng B, Guo Y, Chen C, Lv R, Dong Y, Gao TT, Sun DQ
Scientific reports 2025 Jan 17;15(1):2282
Scientific reports 2025 Jan 17;15(1):2282
CircCCT2/miR-146a-5p/IRAK1 axis promotes the development of head and neck squamous cell carcinoma.
He L, Li L, Zhao L, Guan X, Guo Y, Han Q, Guo H, Liu H, Zhang C
BMC cancer 2025 Jan 14;25(1):84
BMC cancer 2025 Jan 14;25(1):84
Heterogeneous nuclear ribonucleoprotein C promotes non-small cell lung cancer progression by enhancing XB130 mRNA stability and translation.
Wang Q, Gou X, Liu L, Deng D, Zhao Y, Zhou J, Xie Y, Jiang Y, Li J, Zhang J, Liu Y
Cancer cell international 2025 Jan 13;25(1):10
Cancer cell international 2025 Jan 13;25(1):10
Molecule interacting with CasL-2 enhances tumor progression and alters radiosensitivity in cervical cancer.
Teng Y, Zhao H, Xue G, Zhang G, Huang Y, Guo W, Zou K, Zou L
Journal of translational medicine 2025 Jan 11;23(1):44
Journal of translational medicine 2025 Jan 11;23(1):44
Bisphenol S exposure promotes stemness of triple-negative breast cancer cells via regulating Gli1-mediated Sonic hedgehog pathway.
Yi K, Chen W, Zhou X, Xie C, Zhong C, Zhu J
Environmental research 2025 Jan 1;264(Pt 1):120293
Environmental research 2025 Jan 1;264(Pt 1):120293
circ_0004662 contributes to colorectal cancer progression by interacting with hnRNPM.
Zhang Y, Wang J, Quan R, Lyu L
International journal of oncology 2025 Feb;66(2)
International journal of oncology 2025 Feb;66(2)
NEK2 Promotes ESCC Malignant Progression by Inhibiting Cellular Senescence via the FOXM1/c-Myc/p27 Signaling Pathway.
Li J, Wang Y, Wei S, Xu S, Dai S, Zhang L, Tian Z, Zhao L, Lv H
Molecular carcinogenesis 2025 Feb;64(2):244-259
Molecular carcinogenesis 2025 Feb;64(2):244-259
Novel Diagnostic Biomarker BST2 Identified by Integrated Transcriptomics Promotes the Development of Endometriosis via the TNF-α/NF-κB Signaling Pathway.
Jiang L, Wang S, Xia X, Zhang T, Wang X, Zeng F, Ma J, Fang X
Biochemical genetics 2025 Feb;63(1):354-377
Biochemical genetics 2025 Feb;63(1):354-377
β-Catenin mediated TAM phenotype promotes pancreatic cancer metastasis via the OSM/STAT3/LOXL2 axis.
Zhang Y, Zhu X, Chen L, Gao T, Chen G, Zhu J, Wang G, Zuo D
Neoplasia (New York, N.Y.) 2025 Feb;60:101096
Neoplasia (New York, N.Y.) 2025 Feb;60:101096
Epigenetic silencing of JAM3 promotes laryngeal squamous cell carcinoma development by inhibiting the Hippo pathway.
Jia Y, Liu J, Shi J, Zhang C, Wang X, Zhao L, Lou Y, Guan X, Huangfu H
Oncology reports 2025 Feb;53(2)
Oncology reports 2025 Feb;53(2)
Hypericin mediated photodynamic therapy induces ferroptosis via inhibiting the AKT/mTORC1/GPX4 axis in cholangiocarcinoma.
An W, Zhang K, Li G, Zheng S, Cao Y, Liu J
Translational oncology 2025 Feb;52:102234
Translational oncology 2025 Feb;52:102234
Ilicicolin C suppresses the progression of prostate cancer by inhibiting PI3K/AKT/mTOR pathway.
Gan X, Luo X, Chen J, Fang W, Nie M, Lu H, Liu Y, Wang X
Molecular and cellular biochemistry 2025 Feb;480(2):1089-1104
Molecular and cellular biochemistry 2025 Feb;480(2):1089-1104
Ginsenoside Rb prevents the metastasis of hepatocarcinoma by blocking the platelet-tumor cell interaction.
Miao L, Yang Y, Cheng M, Chen L, Han C
Naunyn-Schmiedeberg's archives of pharmacology 2025 Feb;398(2):1721-1733
Naunyn-Schmiedeberg's archives of pharmacology 2025 Feb;398(2):1721-1733
EFNA4-enhanced deubiquitination of SLC7A11 inhibits ferroptosis in hepatocellular carcinoma.
Zhong X, Zhu Z, Du Y, Long L, Xie Z, Zhang Y, Yao H, Lin J, Chen F
Apoptosis : an international journal on programmed cell death 2025 Feb;30(1-2):349-363
Apoptosis : an international journal on programmed cell death 2025 Feb;30(1-2):349-363
FBXO2 as a switch guides a special fate of tumor clones evolving into a highly malignant transcriptional subtype in oral squamous cell carcinoma.
Cheng J, Liu O, Bin X, Tang Z
Apoptosis : an international journal on programmed cell death 2025 Feb;30(1-2):167-184
Apoptosis : an international journal on programmed cell death 2025 Feb;30(1-2):167-184
Negative air ions alleviate nicotine-induced renal damage of spontaneously hypertensive rats via inhibiting oxidative stress and TGF-β/Smad pathway.
Xiao S, Wei T, Xiao M, An Z, Shan M, Luo Z, Zhou J, Li N, Lu X
Ecotoxicology and environmental safety 2025 Feb;291:117882
Ecotoxicology and environmental safety 2025 Feb;291:117882
Prenatal Perfluorooctanoic Acid (PFOA) exposure causes reproductive toxicity by disrupting the formation of transzonal projections (TZPs) and down-regulating Wnt4/β-catenin signaling pathway in progeny.
Du H, Song L, Zhao M, Zhao X, Mu R, Gao S, Zhang B, Wang J
Ecotoxicology and environmental safety 2025 Feb;291:117816
Ecotoxicology and environmental safety 2025 Feb;291:117816
MATN1-AS1 Promotes Tumour Metastasis and Sunitinib Resistance via E2F2 in Clear Cell Renal Cell Carcinoma.
Xiao H, Fei M, Xu Q, Gao Y, Feng R, Liang C, Wang B, Li H
Journal of cellular and molecular medicine 2025 Feb;29(4):e70428
Journal of cellular and molecular medicine 2025 Feb;29(4):e70428
LAMP3-mediated epithelial-mesenchymal transition promotes the invasion and excessive proliferation of fibroblast-like synoviocytes in rheumatoid arthritis.
Zhou W, Cheng H, Fan C, Zhou X, Chen W, Xie C, Hu Y, Chen Y, Wang X, Wu J
Journal of autoimmunity 2025 Feb;151:103359
Journal of autoimmunity 2025 Feb;151:103359
HECW1-Mediated Ubiquitination of HIPK2 Drives Metastasis in Gastric Cancer Through the AKT Signaling Pathway.
Zhang G, Qu W, Huang X, Yi J, Gao H, He J, Xue W
Laboratory investigation; a journal of technical methods and pathology 2025 Feb;105(2):102202
Laboratory investigation; a journal of technical methods and pathology 2025 Feb;105(2):102202
Mechanistic insights into PROS1 inhibition of bladder cancer progression and angiogenesis via the AKT/GSK3β/β-catenin pathway.
Fan XP, Wang JR, Chen SY, Li XR, Cao JL, Wang HB, Ding LY, Che TJ, Yang L
Scientific reports 2025 Feb 8;15(1):4748
Scientific reports 2025 Feb 8;15(1):4748
Endoplasmic reticulum stress-related CLIP4 plays a procarcinogenic role in hepatocellular carcinoma: an integrated analysis.
Wang A, Yan S, Jiang W, Chen X, Huang Y, Zu X, Du X, Fan L, Liu J, Sun G
BMC cancer 2025 Feb 7;25(1):211
BMC cancer 2025 Feb 7;25(1):211
Synthesis of novel deuterated EGFR/ALK dual-target inhibitors and their activity against non-small cell lung cancer.
Nie H, Zhang S, Wang L, Wang M, Qiu J, Jia F, Li X, Tian G, An B
European journal of medicinal chemistry 2025 Feb 5;283:117146
European journal of medicinal chemistry 2025 Feb 5;283:117146
PTOV1 exerts pro-oncogenic role in colorectal cancer by modulating SQSTM1-mediated autophagic degradation of p53.
Fan Y, Li Y, Luo X, Xiang S, Hu J, Zhan J, Chang W, Deng R, Ran X, Zhang Y, Cai Y, Zhu W, Wang H, Liu Z, Wang D
Journal of translational medicine 2025 Feb 4;23(1):157
Journal of translational medicine 2025 Feb 4;23(1):157
COMMD3 Regulates Copper Metabolism via the ATOX1-ATP7A-LOX Axis to Promote Multiple Myeloma Progression.
Wang Y, Zhang B, Fan F, Zhao F, Xu J, Zheng Y, Sun C, Hu Y
Biomedicines 2025 Feb 4;13(2)
Biomedicines 2025 Feb 4;13(2)
RPL22L1 fosters malignant features of cervical cancer via the modulation of DUSP6-ERK axis.
Zhang D, Zhao M, Jiang P, Zhou Y, Yan X, Zhou C, Mu Y, Xiao S, Ji G, Wu N, Sun D, Cui X, Ning S, Meng H, Xiao S, Jin Y
Journal of translational medicine 2025 Feb 28;23(1):244
Journal of translational medicine 2025 Feb 28;23(1):244
Aspirin impedes non-small cell lung cancer development via fine-tuning the CD36 localization regulated by GPIHBP1.
Liu W, Qiao D, Chen J, Gao Y, Okuda K, Shimada Y, Yao L
Translational lung cancer research 2025 Feb 28;14(2):491-512
Translational lung cancer research 2025 Feb 28;14(2):491-512
Discovery of Novel Aromatic Urea-Imidazole Salt Derivatives for Cancer Therapy via Targeting ERK1/2.
Wang M, Yang S, Li X, Zheng Y, Bai Y, Luo W, Zhu G, Chang J, Zhu B
Journal of medicinal chemistry 2025 Feb 27;68(4):4101-4132
Journal of medicinal chemistry 2025 Feb 27;68(4):4101-4132
Molecular mechanism of Gancao Xiexin Decoction regulating EMT and suppressing hepatic metastasis of gastric cancer via the TGF-β1/SMAD pathway.
Liu W, Lu D, Jia S, Yang Y, Meng F, Du Y, Yang Y, Yuan L, Nan Y
Journal of ethnopharmacology 2025 Feb 27;342:119430
Journal of ethnopharmacology 2025 Feb 27;342:119430
PTPRO represses breast cancer lung metastasis by inhibiting the JAK2-YAP axis.
Xiong X, Liu J, Wu X, Yao Z, Meng Y, Liu S, Chen Y, Ren H, Gao S, Qiu X, Zhang H
Scientific reports 2025 Feb 27;15(1):7065
Scientific reports 2025 Feb 27;15(1):7065
Pingxiao pian attenuate invasiveness and proliferation of lung adenocarcinoma through regulating miR-29b-3p/TGF-β1/Smad/EMT pathway.
Feng JN, Chen PR, Yuan SF, Dai Q, Zheng WE, Lin HL
Discover oncology 2025 Feb 24;16(1):232
Discover oncology 2025 Feb 24;16(1):232
Phosphorylation of FOXN3 by NEK6 promotes pulmonary fibrosis through Smad signaling.
Yu J, Li Y, Li Y, Liu X, Huo Q, Wu N, Zhang Y, Zeng T, Zhang Y, Li HY, Lian J, Zhou J, Moses EJ, Geng J, Lin J, Li W, Zhu X
Nature communications 2025 Feb 21;16(1):1865
Nature communications 2025 Feb 21;16(1):1865
A novel piperine derivative HJJ_3_5 inhibits colorectal cancer progression by modulating EMT signaling pathways.
Cheng W, Liu S, He J, Li H, Liu X, Hu Z, Wang X, Wu Z, Xu G, Liu W, Liu B
Biochemical and biophysical research communications 2025 Feb 16;749:151323
Biochemical and biophysical research communications 2025 Feb 16;749:151323
Constructing a highly sensitive duplex immunoassay using AuNPs and AgNPs as nanolabels for investigating the epithelial-mesenchymal transition occurring on circulating tumor cells with lung cancer patients.
Dai Y, He J, Zhou Y, Yu Y, Hui H, Guo L, Yin H
Biosensors & bioelectronics 2025 Feb 15;270:116947
Biosensors & bioelectronics 2025 Feb 15;270:116947
Multi-omics analysis reveals the impact of YAP/TEAD4-mediated EIF5A1 expression on mitochondrial apoptosis and bladder cancer progression.
Li KP, Wan S, Wang CY, Chen SY, Wang L, Liu SH, Yang L
BMC cancer 2025 Feb 11;25(1):234
BMC cancer 2025 Feb 11;25(1):234
CircRNA circACTN4 Promotes the Progression of Epithelial-Mesenchymal Transition in Hepatocellular Carcinoma by Targeting the miR-424-5p/NCAPG/Wnt Axis.
Shan J, Pu J, Chen X, Zhang Y, Li J, Qin L, Shi J, Zhou L, Deng Y
Clinical and experimental medicine 2025 Feb 1;25(1):47
Clinical and experimental medicine 2025 Feb 1;25(1):47
B7-H3 enhances the malignant phenotype of colorectal cancer by activating the Wnt/β-catenin pathway mediated by CYP1B1.
Liu X, Ding J, Zong Q, Mao Y
Tissue & cell 2025 Dec;97:103066
Tissue & cell 2025 Dec;97:103066
IMUP promotes fatty acid metabolism and lung cancer progression by regulating TGF-β/SMAD3 signaling pathway.
Wu S, Liu F, Yao X, Lei Y, Wang W
Tissue & cell 2025 Dec;97:103061
Tissue & cell 2025 Dec;97:103061
TTK Defines a High-Risk Oral Squamous Cell Carcinoma Subtype Through Dual mTORC1/NF-κB Activation.
Jin H, Liu T, Guo Y, Bu W, Liu F, Hou Y
International dental journal 2025 Dec;75(6):103945
International dental journal 2025 Dec;75(6):103945
Taohong Siwu Decoction relieves renal fibrosis: based on network pharmacology and experimental confirmation.
Zhang XQ, Gong Y, Wang YH, Su HW, Tan RZ, Fan JM, Wang L
Renal failure 2025 Dec;47(1):2539948
Renal failure 2025 Dec;47(1):2539948
Mechanistic insights into FUNDC2P4 and HSF1 regulation of EMT in residual hepatocellular carcinoma following insufficient radiofrequency ablation.
Tang N, Yang L, Huang C, Yang L, Yang L, Zhang H, Zeng J
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2025 Dec;42(1):2553210
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2025 Dec;42(1):2553210
TLyp-1-modified exosome-mediated delivery of circRAPGEF5 ASO inhibits lung adenocarcinoma metastasis via regulating the miR-570-3p/SPP1 axis.
Hu T, Zhou C, Chen Y, Fu J, Dai Y, Ling L, Chen Y, Lu Y, He Y, Chen J, Wang Y
Materials today. Bio 2025 Dec;35:102416
Materials today. Bio 2025 Dec;35:102416
CircRAB23 functions as miR-532-3p sponge to promote the malignant proliferation and metastasis of intrahepatic cholangiocarcinoma through HMGA2-EMT axis.
Zhang K, Chen J, Shen S, Zhang H, Xia J, Zhao Y, Yang P, Yan X, Liu C, Ge R, Wang N, Yang X
International journal of biological macromolecules 2025 Dec;332(Pt 2):148685
International journal of biological macromolecules 2025 Dec;332(Pt 2):148685
Cholesterol metabolism in LUAD progression: GJB3 as a key target for cell‑based therapeutic interventions.
Yan Q, Chang W, Wong W, Gong L, Liang D, Yang J, Wang J
Molecular medicine reports 2025 Dec;32(6)
Molecular medicine reports 2025 Dec;32(6)
GLDC interacts with VPS34 to inhibit tumorigenesis and epithelial-mesenchymal transition in hepatocellular carcinoma.
Song Z, Dong H, Zhang K, Qiao B, Li L, Zhang Z, Fan Z, Li J, Li Y, Liu M, Liu Y, Gu X, Zhang T
Pharmaceutical science advances 2025 Dec;3:100072
Pharmaceutical science advances 2025 Dec;3:100072
Deoxycholic Acid and Lipoteichoic Acid cooperatively drive macrophage M2/M1 polarization via TGR5/STAT3 and TLR2/NF-κB to fuel HCC progression in obesity.
Wu J, Zheng W, Ding XZ, Jin QP, Ding MX
Metabolism open 2025 Dec;28:100420
Metabolism open 2025 Dec;28:100420
CircATP5C1 promotes triple-negative breast cancer progression by binding IGF2BP2 to modulate CSF-1 secretion.
Liu H, Wang H, Gao W, Yuan Y, Tang T, Sang M, Liu F, Geng C
Cancer biology & therapy 2025 Dec;26(1):2479926
Cancer biology & therapy 2025 Dec;26(1):2479926
The role and mechanisms of the microRNA-1180-3p/MKNK2/CREB3 signaling axis in tumor progression following insufficient radiofrequency ablation of colorectal cancer liver metastasis.
Gao Y, Zhu J, Xin H, Ni B, Liu Z
Biochemical pharmacology 2025 Dec;242(Pt 3):117216
Biochemical pharmacology 2025 Dec;242(Pt 3):117216
Juglone targets MMP-1 to inhibit gastric cancer progression.
Zhou F, Xie Y, Li X, Peng P
Biochemical pharmacology 2025 Dec;242(Pt 2):117289
Biochemical pharmacology 2025 Dec;242(Pt 2):117289
Single-Cell and Spatial Transcriptomics-Based Research Reveals Association Between M2a Macrophages and Tumor Spread through Air Spaces in Lung Adenocarcinoma.
Ding Y, Zhang H, Wen H, Zhao S, Li J, Liu X, Wang K, Huang Y, Xu M, Sun D
The American journal of pathology 2025 Dec;195(12):2477-2491
The American journal of pathology 2025 Dec;195(12):2477-2491
Acyl-CoA dehydrogenase long chain acts as a tumor-suppressive factor in lung adenocarcinoma progression.
Wei T, Fu G, Zhao J, Cao F, Guo D
Cell adhesion & migration 2025 Dec;19(1):2495676
Cell adhesion & migration 2025 Dec;19(1):2495676
Targeting the ST3 beta-galactoside alpha-2,3-sialyltransferase 1 (ST3Gal1) as a potential therapeutic strategy to overcome anti-VEGF resistance in endometrial cancer.
Liu CH, Yang ST, Chao WT, Lin CH, Lee YC, Lai CR, Hsieh SL, Wang LW, Wang PH
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 2025 Dec;171(3):1343-1354
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 2025 Dec;171(3):1343-1354
Desulfovibrio vulgaris flagellin exacerbates colorectal cancer through activating LRRC19/TRAF6/TAK1 pathway.
Dong Y, Meng F, Wang J, Wei J, Zhang K, Qin S, Li M, Wang F, Wang B, Liu T, Zhong W, Cao H
Gut microbes 2025 Dec;17(1):2446376
Gut microbes 2025 Dec;17(1):2446376
Design, synthesis, and evaluation of 5-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)-1H-indole-2-carboxamide derivatives as anti-HCC agents targeting Nur77.
Hu S, Li X, Yu M, Zhang H, Wang X, Qi C, Huang S, Xu Z, Hu H, Chen S, Fang M, Zeng J
Bioorganic chemistry 2025 Dec;167:109113
Bioorganic chemistry 2025 Dec;167:109113
Adipose-derived mesenchymal stem cell exosomes protect keratinocytes from high-glucose injury by modulating KEAP1/NRF2/HO-1 axis.
Yuan Y, Song S, Xiao Y, Feng R, Li M, Zhang H, Luo L, Wang K, Wang P, Wei L, Zhang Y, Zhang B, Jiang S, Shen K, Guan H, Hu D
Cellular signalling 2025 Dec;136:112172
Cellular signalling 2025 Dec;136:112172
CircLRBA Promotes Epithelial-Mesenchymal Transition, Immune Evasion, Chemoimmunotherapy Resistance and Metastasis Through Stabilizing Twist1.
Wang X, Yang X, Xing L, Chen H, Xie F, Wang B, Shi B, Yang Y, Chen J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(48):e08918
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(48):e08918
Skullcapflavone II Inhibits SLC1A4-Mediated L-Serine Uptake and Promotes Mitochondrial Damage in Gastric Cancer.
Zhao J, Ma YB, Xia RH, Jiang ZC, Zhou Y, Wang YN, Yang MY, Dai JJ, Zhu T, Pan LB, Yuan L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(45):e17225
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(45):e17225
Obesity-induced gut microbiota transplantation promotes the occurrence and development of hepatocellular carcinoma.
Wu J, Zheng W, Ding X, Jin Q, Ding M
Future science OA 2025 Dec;11(1):2599729
Future science OA 2025 Dec;11(1):2599729
METTL3-mediated m(6)A modification regulates OSCC progression via the HNRNPA2B1/FOXQ1 axis.
Wang X, Li Y
Scientific reports 2025 Dec 9;16(1):2362
Scientific reports 2025 Dec 9;16(1):2362
The SREBF2-ACOT7 axis promotes tumor progression and predicts prognosis in diffuse large b-cell lymphoma.
Wang H, Yao X, Wu S, Heng J, Cheng Y, Li L
Scientific reports 2025 Dec 7;15(1):43505
Scientific reports 2025 Dec 7;15(1):43505
KY216-tubulin complex captures VASH2 to inhibit NSCLC metastasis.
He XY, Liu CY, Ding XY, Lin Q, Leng JF, Xiao CM, Zang X, Wang MY, Yin Y, Kong LY, Xia YZ
Nature communications 2025 Dec 4;17(1):191
Nature communications 2025 Dec 4;17(1):191
Bile metabolite palmitic acid augments the migration of gallbladder cancer cells through the ROS/NF-кB signaling pathway.
Da X, Guo Q, Lu Y, Huang J, Mo J, Lu L, Fan M, Zhao X, Guo T, Qi Z, Haoshang, Lu H
Scientific reports 2025 Dec 4;16(1):1262
Scientific reports 2025 Dec 4;16(1):1262
Stem Cells From the Apical Papilla Cultured in Spheroids Spontaneously Differentiate Into Odontoblasts via N-Cadherin Downregulation.
Huang S, Zhang Q, Zhang M, Liu X, Liu M, Sun J, Nie H, Lei L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Dec 31;39(24):e71350
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Dec 31;39(24):e71350
EPI-SauriCas9-based mouse ovarian cancer models recapitulating pten deletion in patients.
Chen W, He P, Ding L, Lou W, Wang Y, Shi W, Fan Z, Sheng Y, Luo J, Tan Z, Wang Y, Di W, Ke X, Yu B
Communications biology 2025 Dec 29;9(1):159
Communications biology 2025 Dec 29;9(1):159
EXOSC3 knockdown induces G1/S phase arrest to suppress hepatocellular carcinoma cell proliferation.
Chen YM, Huo YX, Wei WS, Liu YX, Wang SH, Jiang L, Rong-He, Zhang HL, Jiang LH
Scientific reports 2025 Dec 29;15(1):44684
Scientific reports 2025 Dec 29;15(1):44684
Shikonin inhibits multiple tumor malignant phenotypes and is associated with Hedgehog pathway downregulation in lung adenocarcinoma.
Wang HG, Lu MX, Sheng ML, Lou YB, Xiao YC, Guo A, Yu ZH
Scientific reports 2025 Dec 24;15(1):44516
Scientific reports 2025 Dec 24;15(1):44516
FOXL2 + cancer-associated fibroblasts enhances epithelial ovarian cancer development via TGFβ/Smad signaling.
Zhao L, Nie J, Wang J, Li D, Hao X
BMC cancer 2025 Dec 23;26(1):147
BMC cancer 2025 Dec 23;26(1):147
[PSMD11 overexpression promotes epithelial-mesenchymal transition in gastric cancer and affects patient prognosis].
Zhou R, Yang J, Song B, Chen X, Wang L, Wang Y, Zuo L, Zhu B
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2025 Dec 20;45(12):2747-2755
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2025 Dec 20;45(12):2747-2755
GPX8 is transcriptionally regulated by KLF16 and promotes osteosarcoma progression.
Dong C, Gao Z, Li X
Journal of translational medicine 2025 Dec 2;23(1):1369
Journal of translational medicine 2025 Dec 2;23(1):1369
Porphyromonas gingivalis extracellular vesicles promotes tumor metastasis in esophageal squamous cell carcinoma by inducing PRKACB/JNK/ NFATC2 axis.
Hong K, Zhang H, Qi J, Zhang J, Yin H, Song Q, Wan P, Yu B
Journal of nanobiotechnology 2025 Dec 19;24(1):66
Journal of nanobiotechnology 2025 Dec 19;24(1):66
A novel super-enhancer-driven lncRNA LINC00973 governs head and neck squamous cell carcinoma progression through EN2.
Wang A, Diao P, Xiao N, Wei Y, Wu Y, Wang Y, Wang X, Yan E, Jiang H, Li J, Cheng J
Cell death & disease 2025 Dec 19;17(1):111
Cell death & disease 2025 Dec 19;17(1):111
Targeting the SMAD3/CISD2 axis suppresses bladder cancer progression by promoting ferroptosis in mesenchymal-like bladder cancer cells.
Sun Y, Wang J, Gu D, Lou H, Sun J, Cui Z, Kang W
Cell death & disease 2025 Dec 18;17(1):101
Cell death & disease 2025 Dec 18;17(1):101
METTL3-mediated m6A modification of TACSTD2 mRNA inhibits papillary thyroid cancer progression by activating the TNF signaling and blocking epithelial-mesenchymal transition.
Man J, Zhang Z, Cui T, Shi T
Scientific reports 2025 Dec 18;16(1):857
Scientific reports 2025 Dec 18;16(1):857
The role of hsa_circ_0000520 in breast cancer progression: insights into the miR-542-3p/TMBIM6 regulatory axis.
Wang F, Sun R, Wang B, Qu G
Cancer gene therapy 2025 Dec 18;
Cancer gene therapy 2025 Dec 18;
NAT10-mediated N4-acetylcytidine (ac4C) modification of PIK3R2 mRNA promotes malignant progression of glioblastoma.
Meng X, Dong T, Xu J, Tian K, Yang W, Liu Z, Qian Y, Liu D, Chen C, Bai J, Yong H, Wu X, Shen Z
Cell death & disease 2025 Dec 17;17(1):106
Cell death & disease 2025 Dec 17;17(1):106
Therapeutic targeting of interleukin-17C signaling in carcinogenesis of endometriosis.
Yao B, Zheng R, Yang Y, Zhao Z, Lash GE, Guo B, Pan J, Shuai H, Zhou H, Wang M, Li P
Cell reports. Medicine 2025 Dec 16;6(12):102464
Cell reports. Medicine 2025 Dec 16;6(12):102464
S1PR3 Inhibition in alveolar epithelial cells alleviates pulmonary fibrosis by enhancing alveolar barrier function.
Hao M, Tang G, Zhou E, Fu R, Wang M, Jiang H, Chen X, Bai L, Lv X, Jin J
Respiratory research 2025 Dec 12;27(1):15
Respiratory research 2025 Dec 12;27(1):15
Haematococcus pluvialis ameliorates renal fibrosis by restoring mitophagy via PINK1-Parkin-p62-LC3 signaling.
Wu Y, Chen C, Xie J, Chang X, Zhang Y, Zheng Y, Yuan Y, Hu W, Xie X
NPJ science of food 2025 Dec 11;10(1):9
NPJ science of food 2025 Dec 11;10(1):9
CD36-mediated fatty acid metabolic reprogramming activates synovial fibroblasts and promotes rheumatoid arthritis progression.
Hao J, Zheng J, Liu C, Lu J, Tan M, Li J, Mao J, Yu Y, Wang H, Zhang Y, Shen H
International immunopharmacology 2025 Dec 10;167:115594
International immunopharmacology 2025 Dec 10;167:115594
CircRNA hsa_ circ_0009022 inhibits colorectal cancer progression by sponging miR-576-5p and complexing with FMRP.
Guo J, Wang Y, Yang Y, Feng S, Cai J, Fan S, Wang J, Li N, Qian X, Zhu H
Tissue & cell 2025 Aug;95:102924
Tissue & cell 2025 Aug;95:102924
The role of formin-like protein 1 in pancreatic cancer and its specific effects on immunity.
Liu J, Ding J, Chen L, Shao S, Mei J, Yang X
The Journal of international medical research 2025 Aug;53(8):3000605251365844
The Journal of international medical research 2025 Aug;53(8):3000605251365844
METTL1-mediated m7G modification promotes colorectal cancer metastasis via stabilization of ICAM-1.
Cai S, Mi S, Chen J, Shao L, Yang X, Xue M
Molecular and cellular biochemistry 2025 Aug;480(8):4769-4780
Molecular and cellular biochemistry 2025 Aug;480(8):4769-4780
P5CS deacetylation mediated by SIRT2 facilitates tumor growth by enhancing mitochondrial respiration in hepatocellular carcinoma.
Geng X, Li M, Zhang L, Cai Y, Chen X, Mu X, Wang J, Liu B
Oncogene 2025 Aug;44(31):2746-2761
Oncogene 2025 Aug;44(31):2746-2761
Endoplasmic Reticulum Stress as a Regulator of High Glucose-Induced Epithelial-Mesenchymal Transition in Human Lens Epithelial Cells.
Li H, Yang J
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2025 Aug;41(6):347-354
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2025 Aug;41(6):347-354
Mechanism of (-)-Englerin A and calcium binding on the human TRPC5 channel.
Chen Y, Song K, Guo W, Wei M, Chen L
Protein science : a publication of the Protein Society 2025 Aug;34(8):e70218
Protein science : a publication of the Protein Society 2025 Aug;34(8):e70218
Application of PVA hydrogel loaded with luteolin nanoparticles in anti EMT treatment after GBM.
Zhou L, Zhao Q, Gu L, Tian R, Li Y, Xiong X
Materials today. Bio 2025 Aug;33:101956
Materials today. Bio 2025 Aug;33:101956
Thermosensitive hydrogel composite with si-Cx43 nanoparticles and anti-VEGF agent for synergistic treatment of diabetic retinopathy.
Wen L, Gan M, Xiong S, Dai L, Chen W, Shi W
Materials today. Bio 2025 Aug;33:101917
Materials today. Bio 2025 Aug;33:101917
Homeobox C6 is Up-Regulated and Affects the Pathogenesis of Endometriosis.
Jiang J, Zhang L, Li L
Reproductive sciences (Thousand Oaks, Calif.) 2025 Aug;32(8):2574-2582
Reproductive sciences (Thousand Oaks, Calif.) 2025 Aug;32(8):2574-2582
circGAPVD1 inhibits the progression of gastric cancer through miR-4424/STK4 axis and encoding GAPVD1-137aa protein.
Zhu L, Yao Z, Liu Y, Shao S, Zhou W, Ding J, Mao B, Shao C, Cui F
International journal of biological macromolecules 2025 Aug;319(Pt 3):145408
International journal of biological macromolecules 2025 Aug;319(Pt 3):145408
Dysregulated RNA m6A Methylation Contributes to the Metastasis of Gallbladder Cancer Through miR-146a-5p.
Liu Y, He R, Wang W, Xia Q, Zhang D, Pan S, Wang M, Zhang Q, Xu S, Gong J, Qin R
Journal of cellular and molecular medicine 2025 Aug;29(15):e70764
Journal of cellular and molecular medicine 2025 Aug;29(15):e70764
Single-cell transcriptomics and metabolomics reveal the potential role of ASRGL1 in metabolic reprogramming and invasion of nasopharyngeal carcinoma cells.
Pei Y, Li C, Zhang B, Zheng Q, Chen S, Li J
The international journal of biochemistry & cell biology 2025 Aug;185:106788
The international journal of biochemistry & cell biology 2025 Aug;185:106788
Revealing a new target: Celastrol alleviates pulmonary fibrosis by inhibiting PCAF.
Wang L, Lin F, Liu J, Jia Z, Zhu M, Liu Y, Li Y, Yang L
Bioorganic chemistry 2025 Aug;163:108722
Bioorganic chemistry 2025 Aug;163:108722
Pyrrolidinium Fullerenes as YTHDF1 Inhibitors for Targeted Tumor Therapy.
Wang X, Zhang W, Huo J, Wang Z, Liu Y, Yang L, Zhang S, Chen S, Xu Y, Qi H, Sun J, Pan Y, Lu Y, Li B, Wang Y, Liu M, Li J, Li S, Zhao C, Li Y, Yu F, Wang Z, Guo Q, Li J, Wang C
Advanced healthcare materials 2025 Aug;14(22):e2501360
Advanced healthcare materials 2025 Aug;14(22):e2501360
F-box only protein 10 protects against kidney tubulointerstitial fibrosis by inhibiting ACSL4-mediated lipid peroxidation and ferroptosis.
Hu J, Ma F, Chen X, Lu X, Lu Y, Jiang Y
Cellular signalling 2025 Aug;132:111841
Cellular signalling 2025 Aug;132:111841
HnRNPR promotes non-small cell lung cancer progression by protecting XB130 mRNA from XRN1- and DIS3L2-mediated degradation.
Wang QR, Liu LL, Gou XJ, Liu Y, Zhao Y, Zhang T, Jiang YH, Zhou JJ, Li JL, Zhang J, Xie Y
Cellular signalling 2025 Aug;132:111816
Cellular signalling 2025 Aug;132:111816
Circ847 upregulation via CAFs suppresses salivary adenoid cystic carcinoma progression through VIM-EMT.
Liang Y, Zhou Y, Xu T, Wang Y, Xu X, Chen R, Jiang Q, Lu N, Zhao L, Huang Z, Huang Z
Cellular signalling 2025 Aug;132:111806
Cellular signalling 2025 Aug;132:111806
GATA2 promotes cervical cancer progression under the transcriptional activation of TRIP4.
Wang R, Zhang F, Li J, Yang D, Zhao H, Yuan J, Jia Y, Yu W, Guo W, Zou L, Zou K
Cellular signalling 2025 Aug;132:111778
Cellular signalling 2025 Aug;132:111778
Nanoparticle conjugation of ginsenoside Rh2 enhanced antitumor efficacy on hepatocellular carcinoma.
Sun F, Liu J, Gao S, Zhang M, Sun X, Tian Y, Wang S
Scientific reports 2025 Aug 8;15(1):29111
Scientific reports 2025 Aug 8;15(1):29111
Triptolide targets PPP2CA/ITGA5 axis to suppress lactate-driven ovarian cancer progression.
Ding L, Chen W, Luo C, Weygant N, Lai Y, Ru D, Liu H, Wang Y, Li H
Chinese medicine 2025 Aug 6;20(1):122
Chinese medicine 2025 Aug 6;20(1):122
Promotion of the invasion and metastasis of breast cancer by B7-H3 through CCR5High tumor-associated macrophages.
Dai T, Xu Z, Li Y, Wu M, Qiu Y, Chao Z, Jiang R, Chen Y, Lu L
Cancer cell international 2025 Aug 4;25(1):293
Cancer cell international 2025 Aug 4;25(1):293
Role of the transcription factor SOX8 in hepatocellular carcinoma development and lymph node metastasis.
Teng X, Li TM, Peng K, Li YH, Zhang HJ, Ge B, Xie HX, Yang KJ, Qin CJ, Liao XW, Zhu GZ, Zhou X, Peng T
Translational cancer research 2025 Aug 31;14(8):4882-4905
Translational cancer research 2025 Aug 31;14(8):4882-4905
Exploring the therapeutic effects and molecular mechanisms of total flavonoids of Abelmoschus manihot (L.) Medic in the treatment of IgA nephropathy based on WGCNA.
Wen C, Su H, Li J, Zou J, Gong M, Wang F, Ge H
Journal of ethnopharmacology 2025 Aug 29;352:120191
Journal of ethnopharmacology 2025 Aug 29;352:120191
Exosomal Biglycan promotes gastric cancer progression via M2 polarization and CXCL10-mediated JAK/STAT1 activation.
Li W, Wei H, Liu J, Zhao Z, Wang F, Qiao L, Yin S, Zhang C, Huo M
Cancer letters 2025 Aug 28;626:217758
Cancer letters 2025 Aug 28;626:217758
ADAMTS2 mediates epithelial‒mesenchymal transition and inflammation in high-grade serous ovarian cancer: a study based on bioinformatic analyses and experiments.
Tian Y, Li J, Dong R, Guan Y, Wang Y, Yan L, Zhang J, Kang S
BMC cancer 2025 Aug 26;25(1):1376
BMC cancer 2025 Aug 26;25(1):1376
Paris saponin VII restrains PD-L1 mediated immune evasion through the AKT1 and STAT3 signaling pathways.
Wang Y, Li Y, Zhang Y, Li Y, Zhao L, Tong L, Zhu X, Wang J, Dong Y
Chemico-biological interactions 2025 Aug 25;417:111562
Chemico-biological interactions 2025 Aug 25;417:111562
Senescent fibroblasts secrete CTHRC1 to promote cancer stemness in hepatocellular carcinoma.
Huang H, Peng W, Zhou Q, Zhao Y, Liu L, Cui H, Liang J, Cao M, Chen W, Wang R, Chen S, Xiong S, Cheng B, Bai S
Cell communication and signaling : CCS 2025 Aug 25;23(1):379
Cell communication and signaling : CCS 2025 Aug 25;23(1):379
CircZFR/YTHDF3 axis drives lymph node metastasis in cervical cancer via FASN translation.
Zhou M, Gao Y, Zhang Y, He L, Gao B, Zhang Y, Claret FX, Calin GA, Wang D
Molecular cancer 2025 Aug 21;24(1):218
Molecular cancer 2025 Aug 21;24(1):218
METTL3 promotes peritoneal metastasis of colorectal cancer through regulating m6A modification of NRXN3 mRNA.
Lan TH, Li W, Wang X, Geng YJ, Pang B, Kang LF, Li DY, Pang LY, Zhang XX, Zhang CQ, Wang GQ, Li ZX, Zhou CM, Jiang X, Zhao ZR
iScience 2025 Aug 15;28(8):113165
iScience 2025 Aug 15;28(8):113165
HAS1(high) cancer associated fibroblasts located at the tumor invasion front zone promote oral squamous cell carcinoma invasion via ECM remodeling.
Jin W, Yu Q, Yu L, Zhou T, Wang X, Lu W, Zhang X, Ding L, Hu Q, Ni Y
Journal of experimental & clinical cancer research : CR 2025 Aug 14;44(1):238
Journal of experimental & clinical cancer research : CR 2025 Aug 14;44(1):238
Suppressive effects of Momordica charantia MAP30 on the senescence, proliferation and migration of bladder cancer cells mediated by CENPA.
Lu K, Chao L, Wang J, Wang X, Cai L, Zhang J, Zhang S
Scientific reports 2025 Aug 13;15(1):29679
Scientific reports 2025 Aug 13;15(1):29679
miRNA-204-5p acts as a tumor suppressor in gastric cancer by inhibiting cell migration, invasion, and glycolysis via the RAB22A/PI3K/AKT axis.
Pan W, Tan Y, Chen X, Zeng L, Lv Y, Yang J
Scientific reports 2025 Aug 12;15(1):29536
Scientific reports 2025 Aug 12;15(1):29536
Isoliquiritigenin suppresses fatty acid synthesis and cancer cell migration in anaplastic thyroid carcinoma through AMPK/SREBF1 pathway.
Chen L, Fu Y, Wang J, Lv N, Yu S, Fang Q, Xin W
Archives of biochemistry and biophysics 2025 Apr;766:110352
Archives of biochemistry and biophysics 2025 Apr;766:110352
PLEK2 promotes migration and invasion in pancreatic ductal adenocarcinoma by MMP1 through IL-17 pathway.
Cheng K, Chen Q, Chen Z, Cai Y, Cai H, Wu S, Gao P, Cai Y, Wu Z, Zhou J, Peng B, Wang X
Molecular and cellular biochemistry 2025 Apr;480(4):2401-2412
Molecular and cellular biochemistry 2025 Apr;480(4):2401-2412
METTL3 and HERC4: Elevated Expression and Impact on Hepatocellular Carcinoma Progression.
Sun T, Geng S, Ru Q, Zheng Y
Cancer biotherapy & radiopharmaceuticals 2025 Apr;40(3):173-184
Cancer biotherapy & radiopharmaceuticals 2025 Apr;40(3):173-184
Low molecular weight heparins promote migration and invasion of trophoblast cells through regulating the PI3K/AKT signaling pathway.
Zhou Q, Zhao Y, Fu X
Naunyn-Schmiedeberg's archives of pharmacology 2025 Apr;398(4):4645-4656
Naunyn-Schmiedeberg's archives of pharmacology 2025 Apr;398(4):4645-4656
Cinobufacini Inhibits Survival and Metastasis of Hepatocellular Carcinoma via c-Met Signaling Pathway.
Ma YN, Jiang XM, Hu XQ, Wang L, Gao JJ, Liu H, Qi FH, Song PP, Tang W
Chinese journal of integrative medicine 2025 Apr;31(4):311-325
Chinese journal of integrative medicine 2025 Apr;31(4):311-325
Self-assembled genistein nanoparticles suppress the epithelial-mesenchymal transition in glioblastoma by targeting MMP9.
Zhao Q, Li Y, Sun Q, Wang R, Lu H, Zhang X, Gao L, Cai Q, Liu B, Deng G
Materials today. Bio 2025 Apr;31:101606
Materials today. Bio 2025 Apr;31:101606
FOXA2 Loss in TGF-β1-Induced EMT Suppresses Bisecting-GlcNAc N-Glycan Synthesis in Lung Adenocarcinoma.
Ge W, Wen S, Zhou X, Chen Y, Zeng D, Jiang J, Yang S
Proteomics 2025 Apr;25(8):e202400216
Proteomics 2025 Apr;25(8):e202400216
Design, Synthesis, and Biological Evaluation of Naphthalimide-Polyamine Conjugate as a Potential Anti-Colorectal Cancer Agent.
Dai F, Cao Y, Zhu C, Li Y, Ma X, Wang S, Liu H, Xie X, Gao L, Wang Y, Wang C
Chemistry & biodiversity 2025 Apr;22(4):e202401873
Chemistry & biodiversity 2025 Apr;22(4):e202401873
Isoforskolin, adenylate cyclase agonist, inhibits endothelial-to-mesenchymal transition in atherosclerosis.
Ma Y, Shi Y, Lun J, Wang M, Zhang C, Li X, Yi Q, Cao X, Hu Z, Yang W, Cai H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156520
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156520
Cannabidiol Enhances the Anticancer Activity of Etoposide on Prostate Cancer Cells.
Erzurumlu Y, Catakli D
Cannabis and cannabinoid research 2025 Apr;10(2):258-276
Cannabis and cannabinoid research 2025 Apr;10(2):258-276
Escin Ia ameliorates DSS-induced chronic colitis in mice by inhibiting inflammation and oxidative stress via the LOXL2/MMP-9 pathway.
Yan J, Xu X, Zhu Y, Wang Y, Duan X
Journal of ethnopharmacology 2025 Apr 9;345:119623
Journal of ethnopharmacology 2025 Apr 9;345:119623
ELK4 induced upregulation of HOMER3 promotes the proliferation and metastasis in glioma via Wnt/β-catenin/EMT signaling pathway.
Wang F, Zhou H, Tian Y, Wang X, Huang Y, Tu Y, Li L, Zhen H
Biology direct 2025 Apr 9;20(1):48
Biology direct 2025 Apr 9;20(1):48
Development and Validation of a Prognostic Model for Lung Adenocarcinoma Based on CAF-Related Genes: Unveiling the Role of COX6A1 in Cancer Progression and CAF Infiltration.
Zhu X, Li B, Qin L, Liang T, Hu W, Li J, Wang J
International journal of molecular sciences 2025 Apr 8;26(8)
International journal of molecular sciences 2025 Apr 8;26(8)
Prepubertal Exposure to Tris(2-chloroethyl) Phosphate Disrupts Blood-Testis Barrier Integrity via Ferritinophagy-Mediated Ferroptosis.
Zhao Y, Peng M, Liu H, Zhang X, Fu D
Toxics 2025 Apr 8;13(4)
Toxics 2025 Apr 8;13(4)
Investigation of c-Fos/c-Jun Signaling Pathways in Periostracum Cicadae's Inhibition of EMT in Gastric Tissue.
Liang H, Jin X, He T, Zhou X, Liu Z, Gao W
Pharmaceuticals (Basel, Switzerland) 2025 Apr 7;18(4)
Pharmaceuticals (Basel, Switzerland) 2025 Apr 7;18(4)
Cancer-associated fibroblasts secrete CSF3 to promote TNBC progression via enhancing PGM2L1-dependent glycolysis reprogramming.
Qin W, Chen B, Li X, Zhao W, Wang L, Zhang N, Wang X, Luo D, Liang Y, Li Y, Chen X, Chen T, Yang Q
Cell death & disease 2025 Apr 4;16(1):249
Cell death & disease 2025 Apr 4;16(1):249
Natural Killer Cell Activation Signature Identifies Cyclin B1/CDK1 as a Druggable Target to Overcome Natural Killer Cell Dysfunction and Tumor Invasiveness in Melanoma.
Chen L, Liao W, Huang J, Ding Q, Wu J, Zhang Q, Ding Y, Li D, Li J, Wen X, Zhang X
Pharmaceuticals (Basel, Switzerland) 2025 Apr 30;18(5)
Pharmaceuticals (Basel, Switzerland) 2025 Apr 30;18(5)
The highly expressed GOLPH3 in colorectal cancer cells activates smoothened to drive glycolysis and promote cancer cell growth and radiotherapy resistance.
Zhu K, Fan J, Cai H, Zhou C, Gong Z, Li Z, Yu J
Journal of gastrointestinal oncology 2025 Apr 30;16(2):415-434
Journal of gastrointestinal oncology 2025 Apr 30;16(2):415-434
Inhaled exogenous thymosin beta 4 suppresses bleomycin-induced pulmonary fibrosis in mice via TGF-β1 signalling pathway.
Yu R, Li S, Chen L, Hu E, Chai D, Liu Z, Zhang Q, Mao Y, Zhai Y, Li K, Liu Y, Li X, Zhou H, Yang C, Xu J
The Journal of pharmacy and pharmacology 2025 Apr 3;77(4):582-592
The Journal of pharmacy and pharmacology 2025 Apr 3;77(4):582-592
KIF2C promotes oral squamous cell carcinoma progression via PLK1 upregulation: implications for biomarker development and therapeutic targeting.
Wang C, Su Y, Shi J, Feng G
Journal of molecular histology 2025 Apr 28;56(3):146
Journal of molecular histology 2025 Apr 28;56(3):146
HNF4α-Mediated LINC02560 Promotes Papillary Thyroid Carcinoma Progression by Targeting the miR-505-5p/PDE4C Axis.
Su Y, Xu B, Gao C, Pei W, Ma M, Zhang W, Hu T, Zhang F, Zhang S
Biomolecules 2025 Apr 28;15(5)
Biomolecules 2025 Apr 28;15(5)
Development of Novel PRMT7 Inhibitors for the Treatment of Prostate Cancer.
Li J, Sun C, Zhang Y, Ding J, Yao P, Shen H, Shi Z, Wang W, Zhu Y, Kuang W, Tavus A, Wang L, Yuan K, Wang X, Yang P
Journal of medicinal chemistry 2025 Apr 24;68(8):8244-8268
Journal of medicinal chemistry 2025 Apr 24;68(8):8244-8268
Mechanism of Astragalus Polysaccharide in Alleviating Bovine Mammary Fibrosis Through ROS/NLRP3 Inhibition and EMT Regulation.
Zhang J, Liu K, Yang T, Duan H, Xiao L, Zhang Q, Zhang Y, Dong W, Zhao X
Antioxidants (Basel, Switzerland) 2025 Apr 23;14(5)
Antioxidants (Basel, Switzerland) 2025 Apr 23;14(5)
THBS2-producing matrix CAFs promote colorectal cancer progression and link to poor prognosis via the CD47-MAPK axis.
Liu Z, Ba Y, Shan D, Zhou X, Zuo A, Zhang Y, Xu H, Liu S, Liu B, Zhao Y, Weng S, Wang R, Deng J, Luo P, Cheng Q, Hu X, Yang S, Wang F, Han X
Cell reports 2025 Apr 22;44(4):115555
Cell reports 2025 Apr 22;44(4):115555
CD147 regulates the Rap1 signaling pathway to promote proliferation, migration, and invasion, and inhibit apoptosis in colorectal cancer cells.
Xiaoxia F, Rui L, Meiru C, Lu Y, Ying J
Scientific reports 2025 Apr 20;15(1):13647
Scientific reports 2025 Apr 20;15(1):13647
HPV11E6/E7 induces nasal epithelial hyperplasia through JAK2/STAT3 signaling pathway.
Zhang Y, Tian K, Zheng L, Zhu G, Zhao R, Zhou E, Xue X, Huang S, Chen X, Hu B, Yao W
European journal of medical research 2025 Apr 2;30(1):224
European journal of medical research 2025 Apr 2;30(1):224
P4HA1 is highly expressed in gastric cancer and promotes proliferation and metastasis of gastric cancer cells.
Gao P, Tian H, Ge K, Wang F, Zhao Y, Sun J, Zhang Q
Discover oncology 2025 Apr 19;16(1):575
Discover oncology 2025 Apr 19;16(1):575
STEAP4 facilitates growth, migration, and invasion of prostate carcinoma through upregulation of NOTCH4.
Fan S, Xia Z, Liu W, Zhu Y, Liu X, Gu P, Cui Q
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Apr 15;39(7):e70508
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Apr 15;39(7):e70508
VRK1 promotes epithelial-mesenchymal transition in hepatocellular carcinoma mediated by SNAI1 via phosphorylating CHD1L.
Li J, Song Z, Dong X, Li L, Gu X, Zhang K, Zhang Z, Li Y, Fan Z, Dong H, Liu Y, Liu M, Zhang H, Liu W, Zhang T
Cell death & disease 2025 Apr 15;16(1):302
Cell death & disease 2025 Apr 15;16(1):302
The LysoPS/GPR174 axis drives metastatic progression in esophageal squamous cell carcinoma through cAMP-PKA-CREB signaling activation.
Xiao R, Xu P, Li X, Shen F, Tao S, Zhu X, Cai Y, Feng Z, Liu Z, Xiao H, Ding F, Zhu M
Journal of translational medicine 2025 Apr 14;23(1):438
Journal of translational medicine 2025 Apr 14;23(1):438
CDC25A inhibition sensitizes melanoma cells to doxorubicin and NK cell therapy.
Gao X, Liu F, Zhang B, Ren T, Zheng Y, Niu Z, Ren H, Liu C, Jiang C, Wang C, Huang H, Ma L, Sun Q
Cell death & disease 2025 Apr 11;16(1):276
Cell death & disease 2025 Apr 11;16(1):276
Static magnetic field inhibits epithelial mesenchymal transition and metastasis of glioma.
Sun Z, Zhao W, Fei X, He B, Shi L, Zhang Z, Cai S
Scientific reports 2025 Apr 11;15(1):12430
Scientific reports 2025 Apr 11;15(1):12430
Oroxylin A may promote cell apoptosis and inhibit epithelial-mesenchymal transition in endometrial cancer, associated with the ERβ/PI3K/AKT pathway.
Fan X, Wu L, Cheng T, Lv W, Tian J, Tao J, Tu S, Tan F, Wang Y
Scientific reports 2025 Apr 10;15(1):12225
Scientific reports 2025 Apr 10;15(1):12225
Proliferator-Activated Receptor Alpha Inhibits Abnormal Extracellular Matrix Accumulation and Maintains Energy Metabolism in Late-Onset Fuchs Endothelial Corneal Dystrophy.
Li X, Liu A, Zhou Y, Qi H, Wang J, Chen M, Sun T, Wu J, Huang Y, Wang L
Investigative ophthalmology & visual science 2025 Apr 1;66(4):36
Investigative ophthalmology & visual science 2025 Apr 1;66(4):36
YTHDF3 drives tumor growth and metastasis by recruiting eIF4B to promote Notch2 translation in breast cancer.
Chen H, Lin L, Qiao Z, Pei Y, Gao Y, Lou K, Yang L, Li C, He Y, Bai J, Zhang G
Cancer letters 2025 Apr 1;614:217534
Cancer letters 2025 Apr 1;614:217534
Bisphenol A-induced cancer-associated adipocytes promotes breast carcinogenesis via CXCL12/AKT signaling.
Dong Z, He L, Wu J, Xie C, Geng S, Wu J, Zhong C, Li X
Molecular and cellular endocrinology 2025 Apr 1;599:112473
Molecular and cellular endocrinology 2025 Apr 1;599:112473
A Hybrid Manganese Nanoparticle Simultaneously Eliminates Cancer Stem Cells and Activates STING Pathway to Potentiate Cancer Immunotherapy.
Wu Y, Diao P, Peng Y, Yang Y, Wang Y, Lv P, Li J, Wang D, Cai T, Cheng J
ACS nano 2025 Apr 1;19(12):12237-12252
ACS nano 2025 Apr 1;19(12):12237-12252
Endoglin promotes cell migration and invasion in endometriosis by regulating EMT.
Chen X, Wang J, Tu F, Yang Q, Wang D, Zhu Q
Ginekologia polska 2024;95(9):661-667
Ginekologia polska 2024;95(9):661-667
Single-Cell Spatial-Temporal Analysis of ZNF451 in Mediating Drug Resistance and CD8(+) T Cell Dysfunction.
Tang N, Deng W, Wu Y, Deng Z, Wu X, Xiong J, Zhao Q
Research (Washington, D.C.) 2024;7:0530
Research (Washington, D.C.) 2024;7:0530
Long non-coding RNA HOTAIR promotes tumourigenesis by affecting proliferation, invasion, migration, and apoptosis of liver cancer cells.
Zheng X, Cui R, Jiao Y, Chu D, Wang B, Li N
Folia histochemica et cytobiologica 2024;62(4):165-179
Folia histochemica et cytobiologica 2024;62(4):165-179
IL13RA2 promotes progression of infantile haemangioma by activating glycolysis and the Wnt/β-catenin signaling pathway.
Liu Z, Ma T, Li J, Ren W, Zhang Z
Oncology research 2024;32(9):1453-1465
Oncology research 2024;32(9):1453-1465
Pretreatment with Inflammatory Factors Altered the Secretome of Human Amniotic Epithelial Cells.
Cao W, Zhang Q, Huang Y, Zhang Q, Lai D
Tissue engineering. Part C, Methods 2024;30(6):255-267
Tissue engineering. Part C, Methods 2024;30(6):255-267
Matrix Metalloproteinase 11 Promotes Migration and Invasion of Colorectal Cancer by Elevating Slug Protein.
Pan C, Dai J, Wei Y, Yang L, Ding Z, Wang X, He J
International journal of medical sciences 2024;21(11):2170-2188
International journal of medical sciences 2024;21(11):2170-2188
Knockdown of ribosomal protein L22-like 1 arrests the cell cycle and promotes apoptosis in colorectal cancer.
Li C, Du X, Zhang H, Liu S
CytoJournal 2024;21:45
CytoJournal 2024;21:45
HSPD1 Supports Osteosarcoma Progression through Stabilizing ATP5A1 and thus Activation of AKT/mTOR Signaling.
Zhang Y, Pan R, Li K, Cheang LH, Zhao J, Zhong Z, Li S, Wang J, Zhang X, Cheng Y, Zheng X, He R, Wang H
International journal of biological sciences 2024;20(13):5162-5190
International journal of biological sciences 2024;20(13):5162-5190
KIF15 promotes human glioblastoma progression under the synergistic transactivation of REST and P300.
Yu W, Han S, Hu S, Ru L, Hua C, Xue G, Zhang G, Lv K, Ge H, Wang M, Zheng L, Zhou J, Hou S, Teng Y, Deng W, Guo W
International journal of biological sciences 2024;20(13):5127-5144
International journal of biological sciences 2024;20(13):5127-5144
RUNX1-PDIA5 Axis Promotes Malignant Progression of Glioblastoma by Regulating CCAR1 Protein Expression.
Ji Q, Tu Z, Liu J, Zhou Z, Li F, Zhu X, Huang K
International journal of biological sciences 2024;20(11):4364-4381
International journal of biological sciences 2024;20(11):4364-4381
Hypoxia-driven TNS4 fosters HNSCC tumorigenesis by stabilizing integrin α5β1 complex and triggering FAK-mediated Akt and TGFβ signaling pathways.
Zhao X, Mai Z, Liu L, Lu Y, Cui L, Yu J
International journal of biological sciences 2024;20(1):231-248
International journal of biological sciences 2024;20(1):231-248
Interference with mitochondrial metabolism could serve as a potential therapeutic strategy for advanced prostate cancer.
Wu C, Zhu H, Zhang Y, Ding L, Wang J
PloS one 2024;19(4):e0290753
PloS one 2024;19(4):e0290753
The H2Valdien derivatives regulate the epithelial-mesenchymal transition of hepatoma carcinoma cells through the Hedgehog signaling pathway.
Zhao X, Shao X, Huang X, Dang C, Wang R, Li H
Open medicine (Warsaw, Poland) 2024;19(1):20240954
Open medicine (Warsaw, Poland) 2024;19(1):20240954
PTTG1 induces pancreatic cancer cell proliferation and promotes aerobic glycolysis by regulating c-myc.
Wang Y, Hu J, Chen C, Li Y
Open life sciences 2024;19(1):20220813
Open life sciences 2024;19(1):20220813
miR-34b-5p suppresses the epithelial-mesenchymal transition and metastasis in endometrial cancer AN3CA cells by targeting ZEB1.
Shi L, Yang D, Dong H, Zhang X, Yang C
International journal of clinical and experimental pathology 2024;17(4):137-150
International journal of clinical and experimental pathology 2024;17(4):137-150
Pan-Cancer Screening and Validation of CALU's Role in EMT Regulation and Tumor Microenvironment in Triple-Negative Breast Cancer.
Chen SL, Hu D, Chen TZ, Shen SY, Zhao CF, Wang C, Tong SY, Liu Z, Lin SH, Jin LX, He YB, Zhang ZZ
Journal of inflammation research 2024;17:6743-6764
Journal of inflammation research 2024;17:6743-6764
WTAP knockdown inhibits cell migration through regulating SNAIL1 expression in colorectal cancer.
Han J, Zhang J, Shi H, Wen X
American journal of translational research 2024;16(12):8023-8031
American journal of translational research 2024;16(12):8023-8031
Human umbilical cord mesenchymal stem cells derived-exosomes alleviate LPS-induced cervical inflammation and epithelial-mesenchymal transition.
Yi C, Wang H, Din MAU, Xia Y, Akanyibah FA, Mao F
American journal of translational research 2024;16(11):6903-6913
American journal of translational research 2024;16(11):6903-6913
NEDD1 overexpression increases cell proliferation, tumor immune escape, and drug resistance in LUAD.
Zhuo T, Wu Z, Chen S, Yang C, Huang H, Gan J, Lyu J, Xiao J, Li Z, Qin S, Wu Y
Journal of Cancer 2024;15(9):2460-2474
Journal of Cancer 2024;15(9):2460-2474
KRT80 Promotes Lung Adenocarcinoma Progression and Serves as a Substrate for VCP.
Huang S, Tong W, Yang B, Ma L, Zhang J, Wang C, Xu L, Mei J
Journal of Cancer 2024;15(8):2229-2244
Journal of Cancer 2024;15(8):2229-2244
Integrative Omics Analysis Reveals Metabolic Features of Ground-Glass Opacity-Associated Lung Cancer.
Shi S, Luo D, Yang Y, Wang X
Journal of Cancer 2024;15(7):1848-1862
Journal of Cancer 2024;15(7):1848-1862
HULC-IGF2BP2 Interaction Drives Proliferation and Metastasis in Colorectal Cancer.
Pang Q, Huang S, Wang H, Cao J
Journal of Cancer 2024;15(20):6686-6697
Journal of Cancer 2024;15(20):6686-6697
Capsaicin and Cold exposure promote EMT-mediated premetastatic niche formation to facilitate colorectal cancer metastasis.
Nong F, Xing S
Journal of Cancer 2024;15(2):356-369
Journal of Cancer 2024;15(2):356-369
IPCEF1: Expression Patterns, Clinical Correlates and New Target of Papillary Thyroid Carcinoma.
Yin D, Wang K, Zhao J, Yao J, Han X, Yan B, Dong J, Liao L
Journal of Cancer 2024;15(19):6434-6451
Journal of Cancer 2024;15(19):6434-6451
DOK1 facilitates the advancement of ccRCC.
Xie W, Zhang Y, Shu B, Zhang Z, Zhang R
Journal of Cancer 2024;15(19):6213-6222
Journal of Cancer 2024;15(19):6213-6222
DPP7 as a Potential Therapeutic Marker for Colorectal Cancer.
Ma L, Yang H, Wu S, Wang C, Mei J
Journal of Cancer 2024;15(16):5425-5439
Journal of Cancer 2024;15(16):5425-5439
MPP7 mediates EMT via Wnt/β-catenin pathway to promote polarity changes in epithelial ovarian cancer cells.
Tao C, Ni X
Journal of Cancer 2024;15(14):4490-4502
Journal of Cancer 2024;15(14):4490-4502
Hypoxia-responsive gene F3 Promotes GBM Cell Proliferation and Migration through Activating NF-κB/p65 Signaling Pathway.
Yu A, Wang Y, Qin J, Lei J, Bao W, Dong Z
Journal of Cancer 2024;15(14):4477-4489
Journal of Cancer 2024;15(14):4477-4489
A Model to Predict Prognosis of Renal Cell Clear Cell Carcinoma Based on 3 Angiogenesis-related Long Non-coding RNAs.
Chen G, Zhang T, Li F, Cui C, Huang Z, Gou X, Song Y, Li Y
Journal of Cancer 2024;15(11):3481-3494
Journal of Cancer 2024;15(11):3481-3494
CSF2 Impairs Nrf2 Signaling through the Akt/Mtor Pathway in the Development of Bladder Cancer.
Yu X, Li S, Ke S, Ye C, Wang Q, Wang H, Wang L
Journal of Cancer 2024;15(11):3242-3253
Journal of Cancer 2024;15(11):3242-3253
Macranthoidin B restrains the epithelial-mesenchymal transition through COX-2/PGE(2) pathway in endometriosis.
Ding Y, Yang X, Wei Q, Bi X, Zhang Y, Ma Y, Yang M, Xu X, Li C, Wang Q, Chen Y
Frontiers in pharmacology 2024;15:1492098
Frontiers in pharmacology 2024;15:1492098
The mechanism of PDE7B inhibiting the development of hepatocellular carcinoma through oxidative stress.
Luo Y, Gao H, Zhao J, Chen L, Shao J, Ju L
Frontiers in immunology 2024;15:1469740
Frontiers in immunology 2024;15:1469740
Development and verification of a manganese metabolism- and immune-related genes signature for prediction of prognosis and immune landscape in gastric cancer.
Han X, Leng C, Zhao S, Wang S, Chen S, Wang S, Zhang M, Li X, Lu Y, Wang B, Qi W
Frontiers in immunology 2024;15:1377472
Frontiers in immunology 2024;15:1377472
Identifying and assessing a prognostic model based on disulfidptosis-related genes: implications for immune microenvironment and tumor biology in lung adenocarcinoma.
Wang J, Liu K, Li J, Zhang H, Gong X, Song X, Wei M, Hu Y, Li J
Frontiers in immunology 2024;15:1371831
Frontiers in immunology 2024;15:1371831
TGIF2 is a potential biomarker for diagnosis and prognosis of glioma.
Zhang W, Zhang L, Dong H, Peng H
Frontiers in immunology 2024;15:1356833
Frontiers in immunology 2024;15:1356833
Extracellular putrescine can augment the epithelial-mesenchymal transition of gastric cancer cells by promoting MAL2 expression by elevating H3K27ac in its promoter region.
Bi C, Li C, Xing L, Lu Z, Liu H, Hu T, Wang B, Liu C
American journal of cancer research 2024;14(6):2805-2822
American journal of cancer research 2024;14(6):2805-2822
FSH induces EMT in ovarian cancer via ALKBH5-regulated Snail m6A demethylation.
Xu X, Zhuang X, Yu H, Li P, Li X, Lin H, Teoh JP, Chen Y, Yang Y, Cheng Y, Chen W, Fu X
Theranostics 2024;14(5):2151-2166
Theranostics 2024;14(5):2151-2166
POLR2J expression promotes glioblastoma malignancy by regulating oxidative stress and the STAT3 signaling pathway.
Zheng XL, Li ZD, Luo KZ, Li YL, Liu YH, Shen SY, Shen FY, Li WY, Chen GQ, Zhang C, Zeng LH
American journal of cancer research 2024;14(5):2037-2054
American journal of cancer research 2024;14(5):2037-2054
SSH3 promotes pancreatic cancer proliferation and migration by activating the notch signaling pathway.
Yang C, Quan G, Zhang S, Jiang J
American journal of cancer research 2024;14(4):1815-1830
American journal of cancer research 2024;14(4):1815-1830
High glucose-induced NCAPD2 upregulation promotes malignant phenotypes and regulates EMT via the Wnt/β-catenin signaling pathway in HCC.
Mai Y, Liao C, Wang S, Zhou X, Meng L, Chen C, Qin Y, Deng G
American journal of cancer research 2024;14(4):1685-1711
American journal of cancer research 2024;14(4):1685-1711
FLNB overexpression promotes tumor progression and associates with immune suppression, evasion and stemness in pancreatic cancer.
Fan G, Yan Q, Chen Y, Han M, Wu Z, Ruan S, Zhuang H, Gou Q, Hou B
American journal of cancer research 2024;14(2):709-726
American journal of cancer research 2024;14(2):709-726
Identification of hub genes within the CCL18 signaling pathway in hepatocellular carcinoma through bioinformatics analysis.
Mao J, Tao Y, Wang K, Sun H, Zhang M, Jin L, Pan Y
Frontiers in oncology 2024;14:1371990
Frontiers in oncology 2024;14:1371990
Early short-term hypoxia promotes epidermal cell migration by activating the CCL2-ERK1/2 pathway and epithelial-mesenchymal transition during wound healing.
Jin L, Zhou S, Zhao S, Long J, Huang Z, Zhou J, Zhang Y
Burns & trauma 2024;12:tkae017
Burns & trauma 2024;12:tkae017
The long noncoding RNA MIR4435-2HG enhances the migration, promotion, and glycolysis of nonsmall cell lung cancer cells by targeting the miR-371a-5p/SOX2/PI3K/Akt axis.
Yang J, Su Y, Wang Y, Gao K, Li C, Li M
SAGE open medicine 2024;12:20503121241289290
SAGE open medicine 2024;12:20503121241289290
PCSK9 inhibitor alleviates experimental pulmonary fibrosis-induced pulmonary hypertension via attenuating epithelial-mesenchymal transition by suppressing Wnt/β-catenin signaling in vivo and in vitro.
Lin J, Pan Z, Sun J, Wang X, Yin D, Huo C, Guo Q
Frontiers in medicine 2024;11:1509168
Frontiers in medicine 2024;11:1509168
Circ_0007386 Promotes the Progression of Hepatocellular Carcinoma Through the miR-507/ CCNT2 Axis.
Feng Y, Liang L, Jia W, Wang J, Xu C, Zhu D, Xu B, Zhao W, Ling X, Zhou Y, Kong L, Ding W
Journal of hepatocellular carcinoma 2024;11:1095-1112
Journal of hepatocellular carcinoma 2024;11:1095-1112
The prognostic value and its relationship with immune infiltration of ACLY in clear cell renal cell carcinoma.
Yin B, Liu Q, Zheng Y, Gao H, Lin Y, Zhao Z
Translational oncology 2024 Sep;47:102056
Translational oncology 2024 Sep;47:102056
ACAT1 suppresses clear cell renal cell carcinoma progression by AMPK mediated fatty acid metabolism.
Zheng M, Zhang S, Zhou J, Lin M, Liao Y
Translational oncology 2024 Sep;47:102043
Translational oncology 2024 Sep;47:102043
ETV4 promotes the progression of cholangiocarcinoma by regulating glycolysis via the TGF-β signaling.
Liu F, Wang Q, Wang Z, Zhang S, Ni Q, Chang H
Translational oncology 2024 Sep;47:102035
Translational oncology 2024 Sep;47:102035
N6-methyladenosine triggers renal fibrosis via enhancing translation and stability of ZEB2 mRNA.
Cai Y, Zhou J, Xu A, Huang J, Zhang H, Xie G, Zhong K, Wu Y, Ye P, Wang H, Niu H
The Journal of biological chemistry 2024 Sep;300(9):107598
The Journal of biological chemistry 2024 Sep;300(9):107598
Histone demethylase PHF8 promotes prostate cancer metastasis via the E2F1-SNAI1 axis.
Wang Z, Tang P, Xiao H, Peng S, Chen J, Wang Y, Xu J, Yan Q, Zhang J, Deng J, Ma Q, Zhu H, Luo W, Zhang D, Wang L, Qin J, Lan W, Jiang J, Liu Q
The Journal of pathology 2024 Sep;264(1):68-79
The Journal of pathology 2024 Sep;264(1):68-79
Daphnetin induces ferroptosis in ovarian cancer by inhibiting NAD(P)H:Quinone oxidoreductase 1 (NQO1).
Ma N, Zhang M, Hu J, Wei Z, Zhang S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155876
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155876
PRM1201 effectively inhibits colorectal cancer metastasis via shaping gut microbiota and short- chain fatty acids.
Jia R, Shao S, Zhang P, Yuan Y, Rong W, An Z, Lv S, Feng Y, Liu N, Feng Q, Wang Y, Li Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155795
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155795
The 8-oxoguanine DNA glycosylase-synaptotagmin 7 pathway increases extracellular vesicle release and promotes tumour metastasis during oxidative stress.
Ma Y, Guo J, Rao H, Xin J, Song X, Liu R, Shao S, Hou J, Kong L, Hu Z, He L, Pan F, Guo Z
Journal of extracellular vesicles 2024 Sep;13(9):e12505
Journal of extracellular vesicles 2024 Sep;13(9):e12505
BUB1 induces AKT/mTOR pathway activity to promote EMT induction in human small cell lung cancer.
Wang M, You L, Su Z, He Y, Li D, Liu Z
Scientific reports 2024 Sep 4;14(1):20654
Scientific reports 2024 Sep 4;14(1):20654
CXCL16 promotes proliferation of head and neck squamous cell carcinoma by regulating GPX1-mediated antioxidant levels.
He R, Jiang H, Zhang C, Chen Y, Liu W, Deng X, Zhu X, Liu Y, Zheng C, Zhang Y, Shao C, Duan Y, Xu J
Journal of Zhejiang University. Science. B 2024 Sep 30;26(1):92-106
Journal of Zhejiang University. Science. B 2024 Sep 30;26(1):92-106
CRABP2 promotes cell migration and invasion by activating PI3K/AKT and MAPK signalling pathways via upregulating LAMB3 in prostate cancer.
Wang R, Liao Z, Liu C, Yu S, Xiang K, Wu T, Feng J, Ding S, Yu T, Cheng G, Li S
Journal of biochemistry 2024 Sep 30;176(4):313-324
Journal of biochemistry 2024 Sep 30;176(4):313-324
Clarithromycin attenuates airway epithelial-mesenchymal transition in ovalbumin-induced asthmatic mice through modulation of Kv1.3 channels and PI3K/Akt signaling.
Sun B, Shen K, Zhao R, Li Y, Lin J
International immunopharmacology 2024 Sep 30;139:112624
International immunopharmacology 2024 Sep 30;139:112624
Activin A plays an essential role in migration and proliferation of hepatic stellate cells via Smad3 and calcium signaling.
Zhang W, Zhu L, Fang F, Zhang F, Wang R, Yang K, Liu Y, Cui X
Scientific reports 2024 Sep 3;14(1):20419
Scientific reports 2024 Sep 3;14(1):20419
TGF-β-induced lncRNA TBUR1 promotes EMT and metastasis in lung adenocarcinoma via hnRNPC-mediated GRB2 mRNA stabilization.
Huang L, Liu X, Chen Q, Yang J, Zhang D, Zhao Y, Xu L, Li Z, Liu X, Shao S, Li D, Song Y, Liu X, Zhan Q
Cancer letters 2024 Sep 28;600:217153
Cancer letters 2024 Sep 28;600:217153
Anlotinib reverses osimertinib resistance by inhibiting epithelial-to-mesenchymal transition and angiogenesis in non-small cell lung cancer.
Lyu L, Hua X, Liu J, Zhan S, Zhang Q, Liang X, Feng J, Song Y
Journal of biomedical research 2024 Sep 27;39(5):452-466
Journal of biomedical research 2024 Sep 27;39(5):452-466
CircSEC24B activates autophagy and induces chemoresistance of colorectal cancer via OTUB1-mediated deubiquitination of SRPX2.
Wang D, Li Y, Chang W, Feng M, Yang Y, Zhu X, Liu Z, Fu Y
Cell death & disease 2024 Sep 27;15(9):693
Cell death & disease 2024 Sep 27;15(9):693
Methanolic Extract of Cimicifuga foetida Induces G(1) Cell Cycle Arrest and Apoptosis and Inhibits Metastasis of Glioma Cells.
Chang CH, Tsai HP, Yen MH, Lin CJ
Nutrients 2024 Sep 26;16(19)
Nutrients 2024 Sep 26;16(19)
Mesenchymal stem cells in tumor microenvironment: drivers of bladder cancer progression through mitochondrial dynamics and energy production.
Yang E, Jing S, Wang F, Wang H, Fu S, Yang L, Tian J, Golijanin DJ, El-Deiry WS, Cheng L, Wang Z
Cell death & disease 2024 Sep 20;15(9):688
Cell death & disease 2024 Sep 20;15(9):688
Mediation of FOXA2/IL-6/IL-6R/STAT3 signaling pathway mediates benzo[a]pyrene-induced airway epithelial mesenchymal transformation in asthma.
Tang L, Chen B, Wang B, Xu J, Yan H, Shan Y, Zhao X
Environmental pollution (Barking, Essex : 1987) 2024 Sep 15;357:124384
Environmental pollution (Barking, Essex : 1987) 2024 Sep 15;357:124384
A novel biomarker GATM suppresses proliferation and malignancy of cholangiocarcinoma cells by modulating the JNK/c-Jun signalling pathways.
Yu Y, Gan W, Xiong J, Li J
Heliyon 2024 Sep 15;10(17):e37344
Heliyon 2024 Sep 15;10(17):e37344
LncRNA HIF1A-AS2 promotes triple-negative breast cancer progression and paclitaxel resistance via MRPS23 protein.
Min L, Chen L, Huang D, Zhang Y, You A, Yan X, Li ZH
Heliyon 2024 Sep 15;10(17):e36469
Heliyon 2024 Sep 15;10(17):e36469
Design, Synthesis, and Biological Evaluation of Potent EZH2/LSD1 Dual Inhibitors for Prostate Cancer.
Le M, Lu W, Tan X, Luo B, Yu T, Sun Y, Guo Z, Huang P, Zhu D, Wu Q, Ganesan A, Wen S
Journal of medicinal chemistry 2024 Sep 12;67(17):15586-15605
Journal of medicinal chemistry 2024 Sep 12;67(17):15586-15605
Promotion of apoptosis in melanoma cells by taxifolin through the PI3K/AKT signaling pathway: Screening of natural products using WGCNA and CMAP platforms.
Wang Y, Chen SJ, Ma T, Long Q, Chen L, Xu KX, Cao Y
International immunopharmacology 2024 Sep 10;138:112517
International immunopharmacology 2024 Sep 10;138:112517
Anti-cancer effects of nitazoxanide in epithelial ovarian cancer in-vitro and in-vivo.
Yang X, Liu Z, Wang X, Tian W, Zhao T, Yang Q, Li W, Yang L, Yang H, Jia Y
Chemico-biological interactions 2024 Sep 1;400:111176
Chemico-biological interactions 2024 Sep 1;400:111176
The activation of adenosine monophosphate-activated protein kinase inhibits the migration of tongue squamous cell carcinoma cells by targeting Claudin-1 via epithelial-mesenchymal transition.
Zhou XY, Liu QM, Li Z, Liu XY, Zhao QW, Wang Y, Wu FH, Zhao G, Sun R, Guo XH
Animal models and experimental medicine 2024 Oct;7(5):606-616
Animal models and experimental medicine 2024 Oct;7(5):606-616
MIA3 promotes the degradation of GSH (glutathione) by binding to CHAC1, thereby promoting the progression of hepatocellular carcinoma.
Wanbiao Z, Jing M, Shi Z, Tengxiang C, Xueke Z, Haiyang L
Molecular and cellular biochemistry 2024 Oct;479(10):2769-2784
Molecular and cellular biochemistry 2024 Oct;479(10):2769-2784
Matrine inhibits invasion and migration of gallbladder cancer via regulating the PI3K/AKT signaling pathway.
Mo RL, Li Z, Zhang P, Sheng MH, Han GC, Sun DQ
Naunyn-Schmiedeberg's archives of pharmacology 2024 Oct;397(10):8129-8143
Naunyn-Schmiedeberg's archives of pharmacology 2024 Oct;397(10):8129-8143
IGFBP7 regulates cell proliferation and migration through JAK/STAT pathway in gastric cancer and is regulated by DNA and RNA methylation.
Mo W, Deng L, Cheng Y, Ge S, Wang J
Journal of cellular and molecular medicine 2024 Oct;28(19):e70080
Journal of cellular and molecular medicine 2024 Oct;28(19):e70080
Wnt-5a-Receptor Tyrosine Kinase-Like Orphan Receptor 2 Signaling Provokes Metastatic Colonization and Angiogenesis in Renal Cell Carcinoma, and Prunetin Supresses the Axis Activation.
Chuang WY, Lee CW, Fan WL, Liu TT, Lin ZH, Wang KC, Huang PJ, Yeh YM, Lin TC
The American journal of pathology 2024 Oct;194(10):1967-1985
The American journal of pathology 2024 Oct;194(10):1967-1985
The effects of BMP2 and the mechanisms involved in the invasion and angiogenesis of IDH1 mutant glioma cells.
Xu H, Cao Y, Ruan J, Wang F, He Y, Yang L, Yu T, Du F, Zhang N, Cao X
Journal of neuro-oncology 2024 Oct;170(1):161-171
Journal of neuro-oncology 2024 Oct;170(1):161-171
The expression and role of SUZ12 in lung adenocarcinoma.
Hu X, Hu C, Zhong P
Cancer medicine 2024 Oct;13(19):e70190
Cancer medicine 2024 Oct;13(19):e70190
Hypoxia-induced DTL promotes the proliferation, metastasis, and sorafenib resistance of hepatocellular carcinoma through ubiquitin-mediated degradation of SLTM and subsequent Notch pathway activation.
Chen ZX, Mu MY, Yang G, Qi H, Fu XB, Wang GS, Jiang WW, Huang BJ, Gao F
Cell death & disease 2024 Oct 9;15(10):734
Cell death & disease 2024 Oct 9;15(10):734
Coke oven emissions exacerbate allergic asthma by promoting ferroptosis in airway epithelial cells.
Chen X, Chen H, Zhang P, Ju Q, Wu Z, Xu N, Bi Q, Yang S, Ji J, Yu D, Zhao Y
Journal of hazardous materials 2024 Oct 5;478:135542
Journal of hazardous materials 2024 Oct 5;478:135542
ATF4/NUPR1 axis promotes cancer cell survival and mediates immunosuppression in clear cell renal cell carcinoma.
Lu Y, Chen W, Xuan Y, Li X, Wu S, Wang H, Guo T, Wang C, Tian S, Li H, Lai D, Zhao W, Huang X, Zhao X, Wang B, Zhang X, Li H, Huang Y, Ma X
Discover oncology 2024 Oct 31;15(1):607
Discover oncology 2024 Oct 31;15(1):607
LncRNA FEZF1-AS1 promotes pulmonary fibrosis via up-regulating EZH2 and targeting miR-200c-3p to regulate the ZEB1 pathway.
Liu M, Song L, Lai Y, Gao F, Man J
Scientific reports 2024 Oct 30;14(1):26044
Scientific reports 2024 Oct 30;14(1):26044
The prognostic significance of twist in pancreatic cancer and its role in cancer promotion through the regulation of the immune microenvironment and EMT mechanisms.
Li Q, Liu Y, Zhi R, Wang Y
Discover oncology 2024 Oct 26;15(1):593
Discover oncology 2024 Oct 26;15(1):593
Dibenzolium induces apoptosis and inhibits epithelial-mesenchymal transition (EMT) in bladder cancer cell lines.
Jotatsu Y, Arbiser JL, Moriwaki M, Hirata Y, Takeda S, Takada I, Chen KC, Sung SY, Shigemura K
Scientific reports 2024 Oct 26;14(1):25501
Scientific reports 2024 Oct 26;14(1):25501
RHOF promotes Snail1 lactylation by enhancing PKM2-mediated glycolysis to induce pancreatic cancer cell endothelial-mesenchymal transition.
Zhao R, Yi Y, Liu H, Xu J, Chen S, Wu D, Wang L, Li F
Cancer & metabolism 2024 Oct 26;12(1):32
Cancer & metabolism 2024 Oct 26;12(1):32
Erianin inhibits the progression of pancreatic cancer by directly targeting AKT and ASK1.
Liu R, Qiu M, Deng X, Zhang M, Gao Z, Wang Y, Mei H, Zhai M, Zhang Q, Hao J, Yang Z, Wang H
Cancer cell international 2024 Oct 25;24(1):348
Cancer cell international 2024 Oct 25;24(1):348
CircGNAO1 suppresses hepatocellular carcinoma progression and metastasis via sponging miR-182-5p and regulating FOXO1 expression.
Ju L, Luo Y, Shan J, Lu R, Chen L, Shao J, Bian Z, Yao M
International immunopharmacology 2024 Oct 25;140:112873
International immunopharmacology 2024 Oct 25;140:112873
Construction of an autophagy-related genes risk model as predicting prognosis: BAG1 suppresses growth of clear cell renal cell carcinoma.
Guo J, Chen Q, Han S, Wang T, Xia K, Yu B, Qiu T, Zhou J
International immunopharmacology 2024 Oct 25;140:112737
International immunopharmacology 2024 Oct 25;140:112737
SASS6 promotes tumor proliferation and is associated with TP53 and immune infiltration in lung adenocarcinoma.
Li Z, He L, Li J, Qian J, Wu Z, Zhu Y, Zhuo T, Nong J, Liang H, Zheng H, Huang W, Huang J, Cao J
Clinical and experimental medicine 2024 Oct 24;24(1):243
Clinical and experimental medicine 2024 Oct 24;24(1):243
MYO6 contributes to tumor progression and enzalutamide resistance in castration-resistant prostate cancer by activating the focal adhesion signaling pathway.
Zheng S, Hong Z, Tan Y, Wang Y, Li J, Zhang Z, Feng T, Hong Z, Lin G, Ye D
Cell communication and signaling : CCS 2024 Oct 24;22(1):517
Cell communication and signaling : CCS 2024 Oct 24;22(1):517
Ubiquitin Ligase TRIM22 Inhibits Ovarian Cancer Malignancy via TCF4 Degradation.
Tao T, Zhang Y, Guan C, Wang S, Liu X, Wang M
Molecular cancer research : MCR 2024 Oct 2;22(10):943-956
Molecular cancer research : MCR 2024 Oct 2;22(10):943-956
Integrative Omics Uncovers Low Tumorous Magnesium Content as A Driver Factor of Colorectal Cancer.
Zhang R, Hu M, Liu Y, Li W, Xu Z, He S, Lu Y, Gong Y, Wang X, Hai S, Li S, Qi S, Li Y, Shu Y, Du D, Zhang H, Xu H, Zhou Z, Lei P, Chen HN, Dai L
Genomics, proteomics & bioinformatics 2024 Oct 15;22(4)
Genomics, proteomics & bioinformatics 2024 Oct 15;22(4)
TGFβ1-TNFα regulated secretion of neutrophil chemokines is independent of epithelial-mesenchymal transitions in breast tumor cells.
SenGupta S, Cohen E, Serrenho J, Ott K, Coulombe PA, Parent CA
bioRxiv : the preprint server for biology 2024 Oct 12;
bioRxiv : the preprint server for biology 2024 Oct 12;
SMEK1 promotes clear cell renal cell carcinoma progression via EGFR tyrosine-kinase dependent pathway.
Wang J, Bi W, Lv R, Wang Z, Xin Q, Li K, Chen Y, Liu Q, Zhang X
Cancer letters 2024 Oct 1;601:217148
Cancer letters 2024 Oct 1;601:217148
Regulation of cervical cancer via G15-mediated inhibition of G protein-coupled estrogen receptor.
Zhu Z, Nie X, Deng L, Ding J, Chen J, Zhu J, Yin X, Guo B, Zhang F
Anti-cancer drugs 2024 Oct 1;35(9):817-829
Anti-cancer drugs 2024 Oct 1;35(9):817-829
NOD2 reduces the chemoresistance of melanoma by inhibiting the TYMS/PLK1 signaling axis.
Yun F, Wu N, Yi X, Zhang X, Feng Y, Ni Q, Gai Y, Li E, Yang Z, Zhang Q, Sai B, Kuang Y, Zhu Y
Cell death & disease 2024 Oct 1;15(10):720
Cell death & disease 2024 Oct 1;15(10):720
Circ_0084615 promotes epithelial-mesenchymal transition-mediated tumor progression in hepatocellular carcinoma.
Wu Y, Peng L
Annals of gastroenterological surgery 2024 Nov;8(6):1107-1117
Annals of gastroenterological surgery 2024 Nov;8(6):1107-1117
Liquiritigenin inhibits the migration, invasion, and EMT of prostate cancer through activating ER stress.
Wang C, Liu B, Dan W, Wei Y, Li M, Guo C, Zhang Y, Xie H
Archives of biochemistry and biophysics 2024 Nov;761:110184
Archives of biochemistry and biophysics 2024 Nov;761:110184
N6-methyladenosine reader YTHDF3-mediated zinc finger protein 41 inhibits hepatocellular carcinoma progression by transcriptional repression of Snail.
Li X, Han M, Zhu H, Zhang H, Pan Y, Liang H, Liao Z, Zhang B, Chen X
MedComm 2024 Nov;5(11):e763
MedComm 2024 Nov;5(11):e763
PM(10) dysregulates epithelial barrier function in human corneal epithelial cells that is restored by antioxidant SKQ1.
Somayajulu M, Wright R, Muhammed F, McClellan SA, Ibrahim A, Hazlett LD
Toxicology and applied pharmacology 2024 Nov;492:117122
Toxicology and applied pharmacology 2024 Nov;492:117122
NEU4-mediated desialylation enhances the activation of the oncogenic receptors for the dissemination of ovarian carcinoma.
Shi J, Zhou R, Wang S, Liu Y, Tian B, Liu Y, Chen Y, Hu T, Mu Y, Wang S, Shao X, Yan J, Qu P, Wei D, Yang S, Shi Y, Li J, Wang L
Oncogene 2024 Nov;43(49):3556-3569
Oncogene 2024 Nov;43(49):3556-3569
Data-mining-based biomarker evaluation and experimental validation of SHTN1 for bladder cancer.
Wang Y, Wang J, Zeng T, Qi J
Cancer genetics 2024 Nov;288-289:43-53
Cancer genetics 2024 Nov;288-289:43-53
Long non-coding RNA AC010457.1 promotes the growth and EMT of gastric cancer via the PI3K/AKT axis.
Qian C, Chen Y, Zhao Z, Hu Y, Yi J, Chen S, He J, Chen J, Xue W
Pathology, research and practice 2024 Nov;263:155646
Pathology, research and practice 2024 Nov;263:155646
Novel curcumin derivatives N17 exert anti-cancer effects through the CSNK1G3/AKT axis in triple-negative breast cancer.
Huai Z, Li Z, Xue W, Li S, Huang Y, Cao X, Wei Q, Wang Y
Biochemical pharmacology 2024 Nov;229:116472
Biochemical pharmacology 2024 Nov;229:116472
Dysregulated lncSNHG12 suppresses the invasion and migration of trophoblasts by regulating Dio2/Snail axis to involve in recurrent spontaneous abortion.
Wang Z, Yan S, Liao S, Zhang Y, Wu S, Zhou M, Jin W, Zhang Y, Qi X, Yang C, Yang J, Ding J
Biochemical pharmacology 2024 Nov;229:116459
Biochemical pharmacology 2024 Nov;229:116459
Temperature-Sensitive Polymer-Driven Nanomotors for Enhanced Tumor Penetration and Photothermal Therapy.
Ma B, Yu Y, Li J, Zhang Y, Sun B, Ji A, Song K, Shi L, Hu H, Gao S, Cheng H
Small (Weinheim an der Bergstrasse, Germany) 2024 Nov;20(46):e2403800
Small (Weinheim an der Bergstrasse, Germany) 2024 Nov;20(46):e2403800
Disruption of blood-brain barrier and endothelial-to-mesenchymal transition are attenuated by Astragalus polysaccharides mediated through upregulation of ETS1 expression in experimental autoimmune encephalomyelitis.
Lu Q, Ma J, Zhao Y, Ding G, Wang Y, Qiao X, Cheng X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Nov;180:117521
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Nov;180:117521
Cancer-Associated Endocrine Cells Participate in Pancreatic Carcinogenesis.
Chen Y, Yin X, Xu R, Ruze R, Song J, Yin C, Hu C, Wang C, Xu Q, Zhao Y
Gastroenterology 2024 Nov;167(6):1167-1182.e23
Gastroenterology 2024 Nov;167(6):1167-1182.e23
Quiescent cancer cells induced by high-density cultivation reveals cholesterol-mediated survival and lung metastatic traits.
Liu X, Min Q, Cheng X, Zhang W, Wu Q, Chen X, Lv M, Liu S, Zhao H, Yang D, Tai Y, Lei X, Wang Y, Zhan Q
British journal of cancer 2024 Nov;131(10):1591-1604
British journal of cancer 2024 Nov;131(10):1591-1604
Overexpression of microRNA-611 inhibits TGF-β-induced epithelial-mesenchymal transition and migration in lung cancer cells through MAPKAP1.
Ke B, Huang Y, Gong Y, Zhong H, Shi L
Cellular signalling 2024 Nov;123:111357
Cellular signalling 2024 Nov;123:111357
PLOD1 promote proliferation and migration with glycolysis via the Wnt/β-catenin pathway in THCA.
Cong W, Sun J, Hao Z, Gong M, Liu J
Genomics 2024 Nov;116(6):110943
Genomics 2024 Nov;116(6):110943
Repurposed genipin targeting UCP2 exhibits antitumor activity through inducing ferroptosis in glioblastoma.
Dong H, Sun K, Wang X, Cui M, Ma Y, Li K, Duan W, Zhang H, Zhang L, Sheng Z, He M, Zhang B
Acta biochimica et biophysica Sinica 2024 Nov 8;57(3):403-414
Acta biochimica et biophysica Sinica 2024 Nov 8;57(3):403-414
NSUN2 Promotes Head and Neck Squamous Cell Carcinoma Progression by Targeting EMT-Related Gene LAMC2 in an m(5)C-YBX1-Dependent Manner.
Huang S, Cao C, Tang D, Liu Y, Zhou W, Liu L, Zheng X, He Q, Wang A
Biomedicines 2024 Nov 6;12(11)
Biomedicines 2024 Nov 6;12(11)
HOXC12 promotes the invasion and migration of gastric cancer cells by upregulating SALL4 and activating Wnt/β-catenin signaling pathway.
Zhang J, Hou N, Rao D, Chen Q, Ning Z, Lu M
Discover oncology 2024 Nov 5;15(1):620
Discover oncology 2024 Nov 5;15(1):620
CLIP170 enhancing FOSL1 expression via attenuating ubiquitin-mediated degradation of β-catenin drives renal cell carcinoma progression.
Huang Y, Wen Z, Tao S, Yu Z, Wang X, Li X, Gao L
Cellular and molecular life sciences : CMLS 2024 Nov 28;81(1):467
Cellular and molecular life sciences : CMLS 2024 Nov 28;81(1):467
Epithelial differentiation of gingival mesenchymal stem cells enhances re-epithelialization for full-thickness cutaneous wound healing.
Li Y, Dong L, Chen Y, Cai W, Yang G, Wang Y
Stem cell research & therapy 2024 Nov 28;15(1):455
Stem cell research & therapy 2024 Nov 28;15(1):455
Tumor Protein D53 (TPD53): Involvement in Malignant Transformation of Low-Malignant Oral Squamous Cell Carcinoma Cells.
Watanabe M, Mukudai Y, Kindaichi N, Nara M, Yamada K, Abe Y, Houri A, Shimane T, Shirota T
Biomedicines 2024 Nov 28;12(12)
Biomedicines 2024 Nov 28;12(12)
Intravenous injection of BMSCs modulate tsRNA expression and ameliorate lung remodeling in COPD mice.
Jin T, Liu X, Li G, Sun S, Xie L
Stem cell research & therapy 2024 Nov 25;15(1):450
Stem cell research & therapy 2024 Nov 25;15(1):450
The role of disulfidptosis-associated LncRNA-LINC01137 in Osteosarcoma Biology and its regulatory effects on macrophage polarization.
Tang N, Chen Y, Su Y, Zhang S, Huang T
Functional & integrative genomics 2024 Nov 22;24(6):219
Functional & integrative genomics 2024 Nov 22;24(6):219
Methionine deprivation inhibits glioma proliferation and EMT via the TP53TG1/miR-96-5p/STK17B ceRNA pathway.
Li J, Liu R, Hu H, Huang Y, Shi Y, Li H, Chen H, Cai M, Wang N, Yan T, Wang K, Liu H
NPJ precision oncology 2024 Nov 21;8(1):270
NPJ precision oncology 2024 Nov 21;8(1):270
Arginine methylation-dependent TRIM47 stability mediated by CARM1 promotes the metastasis of hepatocellular carcinoma.
Tang Y, Meng X, Luo X, Yao W, Tian L, Zhang Z, Zhao Y, Xiao J, Zhu H, Hu J
Cell death discovery 2024 Nov 20;10(1):477
Cell death discovery 2024 Nov 20;10(1):477
Loss of DNA Polymerase β Delays Atherosclerosis in ApoE(-/-) Mice Due to Inhibition of Vascular Smooth Muscle Cell Migration.
Zhao L, Chen J, Zhang Y, Liu J, Li W, Sun Y, Chen G, Guo Z, Gu L
International journal of molecular sciences 2024 Nov 2;25(21)
International journal of molecular sciences 2024 Nov 2;25(21)
Effect and underlying mechanism of a photochemotherapy dual-function nanodrug delivery system for head and neck squamous cell carcinoma.
Lin Q, Liu HM, Wu LZ, Yu DD, Hua CY, Zou Y, Jiao WE, Li XP, Chen SM
Journal of translational medicine 2024 Nov 19;22(1):1043
Journal of translational medicine 2024 Nov 19;22(1):1043
Dapagliflozin suppressed gastric cancer growth via regulating OTUD5 mediated YAP1 deubiquitination.
Ren K, Wang X, Ma R, Chen H, Min T, Ma Y, Xie X, Wang W, Deng X, Zhou Z, Li K, Zhu K, Hao N, Dang C, Sun T, Zhang H
European journal of pharmacology 2024 Nov 15;983:177002
European journal of pharmacology 2024 Nov 15;983:177002
FXR deficiency induced ferroptosis via modulation of the CBP-dependent p53 acetylation to suppress breast cancer growth and metastasis.
Huang P, Zhao H, Dai H, Li J, Pan X, Pan W, Xia C, Liu F
Cell death & disease 2024 Nov 14;15(11):826
Cell death & disease 2024 Nov 14;15(11):826
Prohibitin 2 confers NADPH oxidase 1-mediated cytosolic oxidative signaling to promote gastric cancer progression by ERK activation.
Xu L, Meng L, Xiang W, Wang X, Yang J, Shu C, Zhao XH, Rong Z, Ye Y
Free radical biology & medicine 2024 Nov 1;224:130-143
Free radical biology & medicine 2024 Nov 1;224:130-143
APLN promotes the proliferation, migration, and glycolysis of cervical cancer through the PI3K/AKT/mTOR pathway.
Wang Q, Wang B, Zhang W, Zhang T, Liu Q, Jiao X, Ye J, Hao Y, Gao Q, Ma G, Hao C, Cui B
Archives of biochemistry and biophysics 2024 May;755:109983
Archives of biochemistry and biophysics 2024 May;755:109983
TRAIP suppressed apoptosis and cell cycle to promote prostate cancer proliferation via TRAF2-PI3K-AKT pathway activation.
Gu Y, Liang C
International urology and nephrology 2024 May;56(5):1639-1648
International urology and nephrology 2024 May;56(5):1639-1648
Synergistic anticancer effects of ginsenoside CK and gefitinib against gefitinib-resistant NSCLC by regulating the balance of angiogenic factors through HIF-1α/VEGF.
Song X, Wang L, Cai P, Xu Y, Liu Q, Fan D
Toxicology and applied pharmacology 2024 May;486:116938
Toxicology and applied pharmacology 2024 May;486:116938
microRNA-141-3p Suppressed the Progression of the Clear Cell Renal Cell Carcinoma by Targeting Transforming Growth Factor Beta 2 Gene Expression.
Hu X, Li D, Zhan J, Yang C, Wang P, Meng X, Xu S, Che X, Xu L
DNA and cell biology 2024 May;43(5):245-257
DNA and cell biology 2024 May;43(5):245-257
The Jagged-1/Notch1 Signaling Pathway Promotes the Construction of Tissue-Engineered Heart Valves.
Liu K, Wei ZY, Zhong XH, Liu X, Chen H, Pan Y, Zeng W
Tissue engineering. Part A 2024 May;30(9-10):381-392
Tissue engineering. Part A 2024 May;30(9-10):381-392
Daurisoline suppress glioma progression by inhibiting autophagy through PI3K/AKT/mTOR pathway and increases TMZ sensitivity.
Yin HT, Hui-Lu, Yang JH, Li Q, Li M, Zhao QQ, Wen ZP
Biochemical pharmacology 2024 May;223:116113
Biochemical pharmacology 2024 May;223:116113
Targeting miR-31 represses tumourigenesis and dedifferentiation of BRAF(V600E)-associated thyroid carcinoma.
Zhang P, Guan L, Sun W, Zhang Y, Du Y, Yuan S, Cao X, Yu Z, Jia Q, Zheng X, Meng Z, Li X, Zhao L
Clinical and translational medicine 2024 May;14(5):e1694
Clinical and translational medicine 2024 May;14(5):e1694
SOAT1 regulates cholesterol metabolism to induce EMT in hepatocellular carcinoma.
Fu R, Xue W, Liang J, Li X, Zheng J, Wang L, Zhang M, Meng J
Cell death & disease 2024 May 9;15(5):325
Cell death & disease 2024 May 9;15(5):325
The prognostic significance and potential mechanism of DBF4 zinc finger in hepatocellular carcinoma.
Wu Z, Zhang L, Li X, Liu L, Kuang T, Qiu Z, Deng W, Wang W
Scientific reports 2024 May 9;14(1):10662
Scientific reports 2024 May 9;14(1):10662
Modified Lichong decoction intervenes in colorectal cancer by modulating the intestinal flora and the Wnt/β-catenin signaling pathway.
Liu L, Zhao M, Lang X, Jia S, Kang X, Liu Y, Liu J
Journal of cancer research and clinical oncology 2024 May 6;150(5):234
Journal of cancer research and clinical oncology 2024 May 6;150(5):234
Osteocytes support bone metastasis of melanoma cells by CXCL5.
Jia Y, Zhang F, Meng X, Andreev D, Lyu P, Zhang W, Lai C, Schett G, Bozec A
Cancer letters 2024 May 28;590:216866
Cancer letters 2024 May 28;590:216866
miR-1202 regulates BPH-1 cell proliferation, apoptosis, and epithelial-to-mesenchymal transition through targeting HMGCL.
Wang Z, Yin X, Yang P, Gong B, Liu H
Acta biochimica et biophysica Sinica 2024 May 25;56(5):675-687
Acta biochimica et biophysica Sinica 2024 May 25;56(5):675-687
Exosomal circPOLQ promotes macrophage M2 polarization via activating IL-10/STAT3 axis in a colorectal cancer model.
Sun Z, Xu Y, Shao B, Dang P, Hu S, Sun H, Chen C, Wang C, Liu J, Liu Y, Hu J
Journal for immunotherapy of cancer 2024 May 23;12(5)
Journal for immunotherapy of cancer 2024 May 23;12(5)
Methylation-regulated tumor suppressor gene PDE7B promotes HCC invasion and metastasis through the PI3K/AKT signaling pathway.
Du Y, Xu Y, Guo X, Tan C, Zhu X, Liu G, Lyu X, Bei C
BMC cancer 2024 May 22;24(1):624
BMC cancer 2024 May 22;24(1):624
Targeting the HSP47-collagen axis inhibits brain metastasis by reversing M2 microglial polarization and restoring anti-tumor immunity.
Wang L, Li C, Zhan H, Li S, Zeng K, Xu C, Zou Y, Xie Y, Zhan Z, Yin S, Zeng Y, Chen X, Lv G, Han Z, Zhou D, Zhou D, Yang Y, Zhou A
Cell reports. Medicine 2024 May 21;5(5):101533
Cell reports. Medicine 2024 May 21;5(5):101533
The role of USP7-YY1 interaction in promoting colorectal cancer growth and metastasis.
Shao ZY, Yang WD, Qiu H, He ZH, Lu MR, Shen Q, Ding J, Zheng JN, Bai J
Cell death & disease 2024 May 20;15(5):347
Cell death & disease 2024 May 20;15(5):347
IL-1β promotes esophageal squamous cell carcinoma growth and metastasis through FOXO3A by activating the PI3K/AKT pathway.
Chen S, Yang Y, Zheng Z, Zhang M, Chen X, Xiao N, Liu H
Cell death discovery 2024 May 18;10(1):238
Cell death discovery 2024 May 18;10(1):238
E3 ubiquitin ligase UBR5 promotes gemcitabine resistance in pancreatic cancer by inducing O-GlcNAcylation-mediated EMT via destabilization of OGA.
Du Y, Yang Z, Shi H, Chen Z, Chen R, Zhou F, Peng X, Hong T, Jiang L
Cell death & disease 2024 May 16;15(5):340
Cell death & disease 2024 May 16;15(5):340
MAP7 drives EMT and cisplatin resistance in ovarian cancer via wnt/β-catenin signaling.
Chen Q, Li S, Fu F, Huang Q, Zhang R
Heliyon 2024 May 15;10(9):e30409
Heliyon 2024 May 15;10(9):e30409
lncRNA CERS6-AS1 upregulates the expression of ANLN by sponging miR-424-5p to promote the progression and drug resistance of lung adenocarcinoma.
Ting Z, Wu Z, Yang C, Li Z, Huang H, Gan J, Li N, Li X, Lyu J, Wu Y, Qin S
Non-coding RNA research 2024 Mar;9(1):221-235
Non-coding RNA research 2024 Mar;9(1):221-235
PSMD12 promotes non-small cell lung cancer progression through activating the Nrf2/TrxR1 pathway.
Lv J, Ma S, Wang X, Dang J, Ma F
Genes & genomics 2024 Mar;46(3):263-277
Genes & genomics 2024 Mar;46(3):263-277
CD74-ROS1 L2026M mutant enhances autophagy through the MEK/ERK pathway to promote invasion, metastasis and crizotinib resistance in non-small cell lung cancer cells.
Xu X, Li Y, Xu R, Meng Y, Li Z, Zuo D, Wu Y
The FEBS journal 2024 Mar;291(6):1199-1219
The FEBS journal 2024 Mar;291(6):1199-1219
RSK4 promotes the macrophage recruitment and M2 polarization in esophageal squamous cell carcinoma.
He S, Lu M, Zhang L, Wang Z
Biochimica et biophysica acta. Molecular basis of disease 2024 Mar;1870(3):166996
Biochimica et biophysica acta. Molecular basis of disease 2024 Mar;1870(3):166996
Subtle structural alteration in indisulam switches the molecular mechanisms for the inhibitory effect on the migration of gastric cancer cells.
Hou C, Wu X, Shi R, Xing X, Tian S, Eléouët M, Qiao C, Ma J, Xu G
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Mar;172:116259
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Mar;172:116259
MBIP promotes ESCC metastasis by activating MAPK pathway.
Ma Y, Hua Y, Yin X, Jiao Y, Xu E, Yan T, Yang J, Zhang L
Cellular signalling 2024 Mar;115:111040
Cellular signalling 2024 Mar;115:111040
Multi-omics cluster defines the subtypes of CRC with distinct prognosis and tumor microenvironment.
Ma Y, Li J, Zhao X, Ji C, Hu W, Ma Y, Qu F, Sun Y, Zhang X
European journal of medical research 2024 Mar 28;29(1):207
European journal of medical research 2024 Mar 28;29(1):207
ESCRT-I protein UBAP1 controls ventricular expansion and cortical neurogenesis via modulating adherens junctions of radial glial cells.
Lu D, Zhi Y, Su H, Lin X, Lin J, Shi Y, Yi W, Hong C, Zhang T, Fu Z, Chen LY, Zhao Z, Li R, Xu Z, Chen W, Wang N, Xu D
Cell reports 2024 Mar 26;43(3):113818
Cell reports 2024 Mar 26;43(3):113818
PELI1: key players in the oncogenic characteristics of pancreatic Cancer.
Fei X, Zhu C, Liu P, Liu S, Ren L, Lu R, Hou J, Gao Y, Wang X, Pan Y
Journal of experimental & clinical cancer research : CR 2024 Mar 25;43(1):91
Journal of experimental & clinical cancer research : CR 2024 Mar 25;43(1):91
TROP2 is highly expressed in triple-negative breast cancer CTCs and is a potential marker for epithelial mesenchymal CTCs.
Liao Q, Zhang R, Ou Z, Ye Y, Zeng Q, Wang Y, Wang A, Chen T, Chai C, Guo B
Molecular therapy. Oncology 2024 Mar 21;32(1):200762
Molecular therapy. Oncology 2024 Mar 21;32(1):200762
IGF2BP3 prevent HMGB1 mRNA decay in bladder cancer and development.
Lv L, Wei Q, Zhang J, Dong Y, Shan Z, Chang N, Zhao Y, Bian P, Yi Q
Cellular & molecular biology letters 2024 Mar 19;29(1):39
Cellular & molecular biology letters 2024 Mar 19;29(1):39
PDE12 disrupts mitochondrial oxidative phosphorylation and mediates mitochondrial dysfunction to induce oral mucosal epithelial barrier damage in oral submucous fibrosis.
Wei Q, Chen L, Luo W, Chen C, Shi Y, Xie J, Xie X, Luo HB
European journal of pharmacology 2024 Mar 15;967:176353
European journal of pharmacology 2024 Mar 15;967:176353
HDAC3 promotes Sertoli cell maturation and maintains the blood-testis barrier dynamics.
Liu M, He Q, Yuan Z, Chen N, Ren S, Du Q, Wang Y, Han S, Xu C, Lu L, Sun Z, Guan Y, Xie J, Guan Y, Ye L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Mar 15;38(5):e23526
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Mar 15;38(5):e23526
Hypoxia-induced miR-5100 promotes exosome-mediated activation of cancer-associated fibroblasts and metastasis of head and neck squamous cell carcinoma.
Duan Y, Zhou M, Ye B, Yue K, Qiao F, Wang Y, Lai Q, Wu Y, Cao J, Wu Y, Wang X, Jing C
Cell death & disease 2024 Mar 14;15(3):215
Cell death & disease 2024 Mar 14;15(3):215
The circRNA hsa-circ-0013561 regulates head and neck squamous cell carcinoma development via the miR-7-5p/PDK3 axis.
Tian K, Zheng L, Yuan T, Chen X, Chen Q, Xue X, Huang S, He W, Jin M, Zhang Y
Cancer cell international 2024 Mar 1;24(1):91
Cancer cell international 2024 Mar 1;24(1):91
OTUD4 promotes the progression of glioblastoma by deubiquitinating CDK1 and activating MAPK signaling pathway.
Ci M, Zhao G, Li C, Liu R, Hu X, Pan J, Shen Y, Zhang G, Li Y, Zhang L, Liang P, Cui H
Cell death & disease 2024 Mar 1;15(3):179
Cell death & disease 2024 Mar 1;15(3):179
Downregulation of HIGD1B induces mitochondria-mediated apoptosis in gastric cancer cells by inactivating Akt and ERK pathways.
Chen X, Sun B, Li S
Drug development research 2024 Jun;85(4):e22221
Drug development research 2024 Jun;85(4):e22221
ID2 promotes tumor progression and metastasis in thyroid cancer.
Deng Z, Xu M, Ding Z, Kong J, Liu J, Zhang Z, Cao P
Endocrine 2024 Jun;84(3):1051-1063
Endocrine 2024 Jun;84(3):1051-1063
Increased FGL1 Expression Predicts Poor Prognosis and Promotes EMT in Head and Neck Squamous Cell Carcinoma.
Pan Z, Hu W, Huang J, Zheng Z, Lin E, Wang P, Mao L
Biochemical genetics 2024 Jun;62(3):2066-2081
Biochemical genetics 2024 Jun;62(3):2066-2081
Tweety homolog 3 promotes colorectal cancer progression through mutual regulation of histone deacetylase 7.
Lu P, Deng S, Liu J, Xiao Q, Zhou Z, Li S, Xin J, Shu G, Yi B, Yin G
MedComm 2024 Jun;5(6):e576
MedComm 2024 Jun;5(6):e576
SLC11A1 promotes kidney renal clear cell carcinoma (KIRC) progression by remodeling the tumor microenvironment.
Wu D, Zhou Y, Shi X, Yi X, Sheng Z, Fan L, Ge J, Cheng W, Zhou W, He H, Fu D
Toxicology and applied pharmacology 2024 Jun;487:116975
Toxicology and applied pharmacology 2024 Jun;487:116975
Exploring the regulatory role of FBXL19-AS1 in triple-negative breast cancer through the miR-378a-3p/OTUB2 axis.
Guo C, Zhang M, Jin X, Zhu C, Qian J, Tao M
Cell biochemistry and function 2024 Jun;42(4):e4020
Cell biochemistry and function 2024 Jun;42(4):e4020
Amentoflavone reverses epithelial-mesenchymal transition in hepatocellular carcinoma cells by targeting p53 signalling pathway axis.
Jian HY, Zhang JT, Liu Z, Zhang Z, Zeng PH
Journal of cellular and molecular medicine 2024 Jun;28(11):e18442
Journal of cellular and molecular medicine 2024 Jun;28(11):e18442
Lysophosphatidic acid promotes ESCC progression by increasing the level of CCL2 secreted by esophageal epithelial cells.
Ma H, Ma X, Qi L, Zhang Q, Wang T, Guo Q, Li P, Zhang S, Liu S
The journal of gene medicine 2024 Jun;26(6):e3708
The journal of gene medicine 2024 Jun;26(6):e3708
Hypoxia differently regulates the proportion of ALDH(hi) cells in lung squamous carcinoma H520 and adenocarcinoma A549 cells via the Wnt/β-catenin pathway.
Liu N, Zheng Q, Zhang Y, Wang H, Zhang Z, He L, Wei C, Xia H, Liu Y, Wang X
Thoracic cancer 2024 Jun;15(18):1419-1428
Thoracic cancer 2024 Jun;15(18):1419-1428
Glucose regulates the HMGB1 signaling pathway through SIRT1 in glioma.
Wang Y, Wang S, Wang Y, Wang C, Tang Y, Zhang C, Hou S, Yu D, Lin N
Cellular signalling 2024 Jun;118:111137
Cellular signalling 2024 Jun;118:111137
Peptide Transporter 1-Mediated Dipeptide Transport Promotes Hepatocellular Carcinoma Metastasis by Activating MAP4K4/G3BP2 Signaling Axis.
Song F, Zhang Z, Liu W, Xu T, Hu X, Wang Q, Zhang W, Ge L, Zhang C, Hu Q, Qin H, Zhang S, Ren X, Fan W, Zhang Y, Huang P
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jun;11(24):e2306671
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jun;11(24):e2306671
OLFM4 promotes the progression of intestinal metaplasia through activation of the MYH9/GSK3β/β-catenin pathway.
Wei H, Li W, Zeng L, Ding N, Li K, Yu H, Jiang F, Yin H, Xia Y, Deng C, Cai N, Chen X, Gu L, Chen H, Zhang F, He Y, Li J, Zhang C
Molecular cancer 2024 Jun 7;23(1):124
Molecular cancer 2024 Jun 7;23(1):124
POLR1D silencing suppresses lung cancer cells proliferation and migration via inhibition of PI3K-Akt pathway.
Yuan Z, Wang Y, Yang Y, Qin X
Journal of cardiothoracic surgery 2024 Jun 6;19(1):322
Journal of cardiothoracic surgery 2024 Jun 6;19(1):322
The Glabridin from Huangqin Decoction Prevents the Development of Ulcerative Colitis into Colitis-Associated Colorectal Cancer by Modulating MMP1/MMP3 Activity.
Li R, Chi H, Liao X, Cen S, Zou Y
International immunopharmacology 2024 Jun 30;135:112262
International immunopharmacology 2024 Jun 30;135:112262
PSME3 promotes lung adenocarcinoma development by regulating the TGF-β/SMAD signaling pathway.
Wang S, Li Y, Jin K, Suda K, Li R, Zhang H, Tian H
Translational lung cancer research 2024 Jun 30;13(6):1331-1345
Translational lung cancer research 2024 Jun 30;13(6):1331-1345
Analysis of cell death-related genes to evaluate the prognostic and immunotherapeutic value in bladder cancer.
Gao M, Guo H, Xu H, Jin X, Liu Y, Chen Z, Wang X
Heliyon 2024 Jun 30;10(12):e33200
Heliyon 2024 Jun 30;10(12):e33200
N-cadherin dynamically regulates pediatric glioma cell migration in complex environments.
Kim D, Olson JM, Cooper JA
The Journal of cell biology 2024 Jun 3;223(6)
The Journal of cell biology 2024 Jun 3;223(6)
IFI16 promotes the progression of clear cell renal cell carcinoma through the IL6/PI3K/AKT axis.
Lu K, Zhao Y, Li Y, Fu Z, Chen Y, Kong Y, Li G
Journal of translational medicine 2024 Jun 3;22(1):533
Journal of translational medicine 2024 Jun 3;22(1):533
ISG15 promotes tumor progression via IL6/JAK2/STAT3 signaling pathway in ccRCC.
Xie W, Zhang Y, Zhang Z, Li Q, Tao L, Zhang R
Clinical and experimental medicine 2024 Jun 29;24(1):140
Clinical and experimental medicine 2024 Jun 29;24(1):140
The Therapeutic Role of NPS-1034 in Pancreatic Ductal Adenocarcinoma as Monotherapy and in Combination with Chemotherapy.
Luan YZ, Wang CC, Yu CY, Chang YC, Sung WW, Tsai MC
International journal of molecular sciences 2024 Jun 24;25(13)
International journal of molecular sciences 2024 Jun 24;25(13)
Repurposing homoharringtonine for thyroid cancer treatment through TIMP1/FAK/PI3K/AKT signaling pathway.
Xi C, Zhang G, Sun N, Liu M, Ju N, Shen C, Song H, Luo Q, Qiu Z
iScience 2024 Jun 21;27(6):109829
iScience 2024 Jun 21;27(6):109829
Association of mitochondrial phosphoenolpyruvate carboxykinase with prognosis and immune regulation in hepatocellular carcinoma.
Li C, Zhang ED, Ye Y, Xiao Z, Huang H, Zeng Z
Scientific reports 2024 Jun 18;14(1):14051
Scientific reports 2024 Jun 18;14(1):14051
An Antibody of the Secreted Isoform of Disintegrin and Metalloprotease 9 (sADAM9) Inhibits Epithelial-Mesenchymal Transition and Migration of Prostate Cancer Cell Lines.
Jotatsu Y, Sung SY, Wu MH, Takeda S, Hirata Y, Maeda K, Fang SB, Chen KC, Shigemura K
International journal of molecular sciences 2024 Jun 17;25(12)
International journal of molecular sciences 2024 Jun 17;25(12)
SIAH2 is specifically expressed during cervical carcinogenesis, and closely relates to the abnormal proliferation of cervical epithelial cells.
Jing LP, Li M, Xia XY, Zheng X, Chen JY, He J, Zhuang XW
Heliyon 2024 Jun 15;10(11):e31487
Heliyon 2024 Jun 15;10(11):e31487
IRTKS contributes to the malignant progression of cervical cancer cells.
Zhang Y, Yi F, Zhang X, Song J, Cai J, Lai J, Song F
Medical oncology (Northwood, London, England) 2024 Jun 13;41(7):174
Medical oncology (Northwood, London, England) 2024 Jun 13;41(7):174
DUSP5 regulated by YTHDF1-mediated m6A modification promotes epithelial-mesenchymal transition and EGFR-TKI resistance via the TGF-β/Smad signaling pathway in lung adenocarcinoma.
Fan W, Xing Y, Yan S, Liu W, Ning J, Tian F, Wang X, Zhan Y, Luo L, Cao M, Huang J, Cai L
Cancer cell international 2024 Jun 13;24(1):208
Cancer cell international 2024 Jun 13;24(1):208
FLNA overexpression promotes papillary thyroid cancer aggression via the FAK/AKT signaling pathway.
Liang W, Zhang Y, Guo Y, Zhang P, Jin J, Guan H, Li Y
Endocrine connections 2024 Jun 1;13(6)
Endocrine connections 2024 Jun 1;13(6)
Loss of PTPRS elicits potent metastatic capability and resistance to temozolomide in glioblastoma.
Zhang Y, Chang L, Huang P, Cao M, Hong R, Zhao X, He X, Xu L
Molecular carcinogenesis 2024 Jul;63(7):1235-1247
Molecular carcinogenesis 2024 Jul;63(7):1235-1247
Parkin deficiency promotes liver cancer metastasis by TMEFF1 transcription activation via TGF-β/Smad2/3 pathway.
Su Q, Wang JJ, Ren JY, Wu Q, Chen K, Tu KH, Zhang Y, Leong SW, Sarwar A, Han X, Zhang M, Dai WF, Zhang YM
Acta pharmacologica Sinica 2024 Jul;45(7):1520-1529
Acta pharmacologica Sinica 2024 Jul;45(7):1520-1529
LncRNA AC100826.1 regulated PLCB1 to promote progression in non-small cell lung cancer.
Dai S, Wang Q, Lyu Y, Chen Z, Liu X, Zhao G, Zhang H
Thoracic cancer 2024 Jul;15(19):1477-1489
Thoracic cancer 2024 Jul;15(19):1477-1489
LINC00460 promotes neuroblastoma tumorigenesis and cisplatin resistance by targeting miR-149-5p/DLL1 axis and activating Notch pathway in vitro and in vivo.
Xu Y, Qiu Z, Chen J, Huang L, Zhang J, Lin J
Drug delivery and translational research 2024 Jul;14(7):2003-2018
Drug delivery and translational research 2024 Jul;14(7):2003-2018
Baohuoside I chemosensitises breast cancer to paclitaxel by suppressing extracellular vesicle/CXCL1 signal released from apoptotic cells.
Wang S, Li J, Xu S, Wang N, Pan B, Yang B, Zheng Y, Zhang J, Peng F, Peng C, Wang Z
Journal of extracellular vesicles 2024 Jul;13(7):e12493
Journal of extracellular vesicles 2024 Jul;13(7):e12493
Targeting the PI3K/AKT/mTOR pathway offer a promising therapeutic strategy for cholangiocarcinoma patients with high doublecortin-like kinase 1 expression.
Liang Z, Ge Y, Li J, Bai Y, Xiao Z, Yan R, An G, Zhang D
Journal of cancer research and clinical oncology 2024 Jul 9;150(7):342
Journal of cancer research and clinical oncology 2024 Jul 9;150(7):342
Deciphering glutamine metabolism patterns for malignancy and tumor microenvironment in clear cell renal cell carcinoma.
Wu G, Li T, Chen Y, Ye S, Zhou S, Tian X, Anwaier A, Zhu S, Xu W, Hao X, Ye D, Zhang H
Clinical and experimental medicine 2024 Jul 6;24(1):152
Clinical and experimental medicine 2024 Jul 6;24(1):152
Immunohistochemistry identifies E-cadherin, N-cadherin and focal adhesion kinase (FAK) as predictors of stage I non-small cell lung carcinoma spread through the air spaces (STAS), and the combinations as prognostic factors.
Meng Y, Wang Y, Liu L, Wu R, Zhang Q, Chen Z, Yao Y, Li X, Gong Y, Li H, Wang Z, Liu H
Translational lung cancer research 2024 Jul 30;13(7):1450-1462
Translational lung cancer research 2024 Jul 30;13(7):1450-1462
CCL2 promotes EGFR-TKIs resistance in non-small cell lung cancer via the AKT-EMT pathway.
Diao Y, Huang S, Liu F, Liao S, Guan C, Xiong X, Zhang P, Li J, Zhang W, Ying Y
Acta biochimica et biophysica Sinica 2024 Jul 3;56(10):1549-1560
Acta biochimica et biophysica Sinica 2024 Jul 3;56(10):1549-1560
Construction of the pulmonary bio-adhesive delivery system of nintedanib nanocrystalline for effective treatment of pulmonary fibrosis.
Yun CX, Huan ML, Zhu X, Wan YH, Zou JB, Zhang BL
International journal of pharmaceutics 2024 Jul 20;660:124302
International journal of pharmaceutics 2024 Jul 20;660:124302
Single-Cell and Spatial Transcriptome Profiling Identifies the Transcription Factor BHLHE40 as a Driver of EMT in Metastatic Colorectal Cancer.
Yang S, Zhang D, Sun Q, Nie H, Zhang Y, Wang X, Huang Y, Sun Y
Cancer research 2024 Jul 2;84(13):2202-2217
Cancer research 2024 Jul 2;84(13):2202-2217
Alpha 1,3 N-Acetylgalactosaminyl Transferase (GTA) Impairs Invasion Potential of Trophoblast Cells in Preeclampsia.
Li Y, Wu H, Pei X, Liu S, Yan Q
International journal of molecular sciences 2024 Jul 2;25(13)
International journal of molecular sciences 2024 Jul 2;25(13)
Fasudil attenuates oxidative stress-induced partial epithelial-mesenchymal transition of tubular epithelial cells in hyperuricemic nephropathy via activating Nrf2.
Cao Y, Wang Y, Li W, Feng J, Chen Y, Chen R, Hu L, Wei J
European journal of pharmacology 2024 Jul 15;975:176640
European journal of pharmacology 2024 Jul 15;975:176640
DNA demethylase TET2-mediated reduction of HADHB expression contributes to cadmium-induced malignant progression of colorectal cancer.
Li L, Jiang M, Wang W, Cao X, Ma Q, Han J, Liu Z, Huang Y, Chen Y
Ecotoxicology and environmental safety 2024 Jul 15;280:116579
Ecotoxicology and environmental safety 2024 Jul 15;280:116579
LINC01133 promotes pancreatic ductal adenocarcinoma epithelial-mesenchymal transition mediated by SPP1 through binding to Arp3.
Yang Y, Gong Y, Ding Y, Sun S, Bai R, Zhuo S, Zhang Z
Cell death & disease 2024 Jul 10;15(7):492
Cell death & disease 2024 Jul 10;15(7):492
CHMP3 promotes the progression of hepatocellular carcinoma by inhibiting caspase‑1‑dependent pyroptosis.
Zheng Y, Yang S, Dai W, Wang J, Bi S, Zhang X, Zheng Z, Sun Y, Wu S, Kong J
International journal of oncology 2024 Jan;64(1)
International journal of oncology 2024 Jan;64(1)
PKMYT1 induced by YAP/TEAD1 gives rise to the progression and worse prognosis of bladder cancer.
Wang M, Zhang C, Ying Y, Hua M, Meng F, Wang Z, Liu A, Zeng S, Zhang Z, Xu C
Molecular carcinogenesis 2024 Jan;63(1):160-172
Molecular carcinogenesis 2024 Jan;63(1):160-172
MicroRNA-10a-5p-mediated downregulation of GATA6 inhibits tumor progression in ovarian cancer.
Gao F, Wu Q, Lu D
Human cell 2024 Jan;37(1):271-284
Human cell 2024 Jan;37(1):271-284
Nucleoporin 93, a new substrate of the E3 ubiquitin protein ligase HECTD1, promotes esophageal squamous cell carcinoma progression.
Zhang J, Xin Y, Ling X, Liang H, Zhang L, Fang C, Ma J
Human cell 2024 Jan;37(1):245-257
Human cell 2024 Jan;37(1):245-257
Hematoporphyrin derivative photodynamic therapy induces apoptosis and suppresses the migration of human esophageal squamous cell carcinoma cells by regulating the PI3K/AKT/mTOR signaling pathway.
Wei X, Ni J, Yuan L, Li X
Oncology letters 2024 Jan;27(1):17
Oncology letters 2024 Jan;27(1):17
17β-Estradiol mediates TGFBR3/Smad2/3 signaling to attenuate the fibrosis of TGF-β1-induced bovine endometrial epithelial cells via GPER.
Fang Z, Wang Q, Duan H, Sheng X, Qi X, Xing K, Liu B, Chang D, Guo Y, Wang X, Xiao L
Journal of cellular physiology 2024 Jan;239(1):166-179
Journal of cellular physiology 2024 Jan;239(1):166-179
The homologous tumor-derived-exosomes loaded with miR-1270 selectively enhanced the suppression effect for colorectal cancer cells.
Jin Y, Sun L, Chen Y, Lu Y
Cancer medicine 2024 Jan;13(1):e6936
Cancer medicine 2024 Jan;13(1):e6936
Hsa_circ_0013561 promotes progression of nasopharyngeal carcinoma by activating JAK2/STAT3 signaling pathway.
Kaisai T, Mantang Z, Tailei Y, Liying Z, Xiaoping C, Mingming J, Yi Z
Brazilian journal of otorhinolaryngology 2024 Jan-Feb;90(1):101362
Brazilian journal of otorhinolaryngology 2024 Jan-Feb;90(1):101362
Plasma CircCYP24A1 as a Novel Biomarker of Esophageal Squamous Cell Carcinoma.
Zhang R, Liu J, Yang H, Tan J, Xiong R, Liu Y, Feng G, Song G, Liu K
Technology in cancer research & treatment 2024 Jan-Dec;23:15330338241295313
Technology in cancer research & treatment 2024 Jan-Dec;23:15330338241295313
TMCO1 regulates cell proliferation, metastasis and EMT signaling through CALR, promoting ovarian cancer progression and cisplatin resistance.
Sun G, Gong S, Lan S, He Y, Sun Y, Zhang Z
Cellular and molecular biology (Noisy-le-Grand, France) 2024 Jan 31;70(1):99-109
Cellular and molecular biology (Noisy-le-Grand, France) 2024 Jan 31;70(1):99-109
Lactate accumulation induced by Akt2-PDK1 signaling promotes pulmonary fibrosis.
Sun Z, Ji Z, He W, Duan R, Qu J, Yu G
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jan 31;38(2):e23426
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jan 31;38(2):e23426
CTSC promoted the migration and invasion of glioma cells via activation of STAT3/SERPINA3 axis.
Li Q, Wan C, Zhang Z, Liu G, Wang S
Gene 2024 Jan 30;893:147948
Gene 2024 Jan 30;893:147948
Transcription factor FOXP4 inversely governs tumor suppressor genes and contributes to thyroid cancer progression.
Zhou T, Ma N, Zhang YL, Chen XH, Luo X, Zhang M, Gao QJ, Zhao DW
Heliyon 2024 Jan 30;10(2):e23875
Heliyon 2024 Jan 30;10(2):e23875
The Analysis of Embryoid Body Formation and Its Role in Retinal Organoid Development.
Heredero Berzal A, Wagstaff EL, Ten Asbroek ALMA, Ten Brink JB, Bergen AA, Boon CJF
International journal of molecular sciences 2024 Jan 24;25(3)
International journal of molecular sciences 2024 Jan 24;25(3)
FBXO28 promotes cell proliferation, migration and invasion via upregulation of the TGF-beta1/SMAD2/3 signaling pathway in ovarian cancer.
Song G, Sun Z, Chu M, Zhang Z, Chen J, Wang Z, Zhu X
BMC cancer 2024 Jan 24;24(1):122
BMC cancer 2024 Jan 24;24(1):122
Circular RNA DNAH14 molecular mechanism in an experimental model of hepatocellular carcinoma treated with Cobalt chloride to mimic the hypoxia-like response of transcatheter arterial chemoembolization.
Liao Q, Xia W, Chen J, Wang K, Xiao E
Scientific reports 2024 Jan 23;14(1):1992
Scientific reports 2024 Jan 23;14(1):1992
The dopamine receptor D1 inhibitor, SKF83566, suppresses GBM stemness and invasion through the DRD1-c-Myc-UHRF1 interactions.
Xue Z, Zhang Y, Zhao R, Liu X, Grützmann K, Klink B, Zhang X, Wang S, Zhao W, Sun Y, Han M, Wang X, Hu Y, Liu X, Yang N, Qiu C, Li W, Huang B, Li X, Bjerkvig R, Wang J, Zhou W
Journal of experimental & clinical cancer research : CR 2024 Jan 22;43(1):25
Journal of experimental & clinical cancer research : CR 2024 Jan 22;43(1):25
ERH gene knockdown inhibits the proliferation and migration of ARPE-19 cells through MCM complex and EMT process.
Li M, Zhang Z, Guan L, Ji S, Lu P
Gene 2024 Jan 20;892:147855
Gene 2024 Jan 20;892:147855
DDX60 Promotes Migration and Invasion of Head and Neck Squamous Cell Carcinoma Cell through the NF-κB/IFI27 Signaling Pathway.
Han Y, Gao J, Liu L
Frontiers in bioscience (Landmark edition) 2024 Jan 17;29(1):14
Frontiers in bioscience (Landmark edition) 2024 Jan 17;29(1):14
A transcriptome based molecular classification scheme for cholangiocarcinoma and subtype-derived prognostic biomarker.
Fan Z, Zou X, Wang G, Liu Y, Jiang Y, Wang H, Zhang P, Wei F, Du X, Wang M, Sun X, Ji B, Hu X, Chen L, Zhou P, Wang D, Bai J, Xiao X, Zuo L, Xia X, Yi X, Lv G
Nature communications 2024 Jan 11;15(1):484
Nature communications 2024 Jan 11;15(1):484
N-cadherin dynamically regulates pediatric glioma cell migration in complex environments.
Kim D, Olson JM, Cooper JA
bioRxiv : the preprint server for biology 2024 Jan 11;
bioRxiv : the preprint server for biology 2024 Jan 11;
Panax notoginseng saponin alleviates pulmonary fibrosis in rats by modulating the renin-angiotensin system.
Li H, Wang YG, Chen TF, Gao YH, Song L, Yang YF, Gao Y, Huo W, Zhang GP
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):116979
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):116979
Hydrogen sulfide attenuates atherosclerosis induced by low shear stress by sulfhydrylating endothelium NFIL3 to restrain MEST mediated endothelial mesenchymal transformation.
Zhou K, Luo W, Gui DD, Ren Z, Wei DH, Liu LS, Li GH, Tang ZH, Xiong WH, Hu HJ, Jiang ZS
Nitric oxide : biology and chemistry 2024 Jan 1;142:47-57
Nitric oxide : biology and chemistry 2024 Jan 1;142:47-57
Cold atmospheric plasma sensitizes head and neck cancer to chemotherapy and immune checkpoint blockade therapy.
Wang Y, Mang X, Li D, Wang Z, Chen Y, Cai Z, Tan F
Redox biology 2024 Feb;69:102991
Redox biology 2024 Feb;69:102991
NMI promotes tumor progression and gemcitabine resistance in pancreatic cancer via STAT3-IFIT3 axis.
Hu H, Li B, Chen H, Fan G, Ye Z, Ji S, Yu X, Xu X, Qin Y
Molecular carcinogenesis 2024 Feb;63(2):195-208
Molecular carcinogenesis 2024 Feb;63(2):195-208
Spindle and kinetochore-related complex subunit 3 has a protumour function in osteosarcoma by activating the Notch pathway.
Liang G, Duan C, He J, Shi L
Toxicology and applied pharmacology 2024 Feb;483:116826
Toxicology and applied pharmacology 2024 Feb;483:116826
Serabelisib regulates GSDMD-mediated pyroptosis, apoptosis and migration of hepatoma cells via the PI3K/Akt/E-cadherin signaling pathway.
Li M, Huang Z, Zhou Y
Advances in clinical and experimental medicine : official organ Wroclaw Medical University 2024 Feb;33(2):171-181
Advances in clinical and experimental medicine : official organ Wroclaw Medical University 2024 Feb;33(2):171-181
Comprehensive analysis of PSMD family members and validation of PSMD9 as a potential therapeutic target in human glioblastoma.
Li Y, Liu X, Zhao F, Zhao Z, Li X, Wang J, Huang B, Chen A
CNS neuroscience & therapeutics 2024 Feb;30(2):e14366
CNS neuroscience & therapeutics 2024 Feb;30(2):e14366
Promoting effect and immunologic role of secretogranin II on bladder cancer progression via regulating MAPK and NF-κB pathways.
Zhou J, Dong C, Tan J, Wang G, Li Z, Li S, He Z
Apoptosis : an international journal on programmed cell death 2024 Feb;29(1-2):121-141
Apoptosis : an international journal on programmed cell death 2024 Feb;29(1-2):121-141
Exosome-delivered miR-410-3p reverses epithelial-mesenchymal transition, migration and invasion of trophoblasts in spontaneous abortion.
Chen ZY, Li Z, Zong Y, Xia B, Luo SP, Deng GP, Gao J
Journal of cellular and molecular medicine 2024 Feb;28(3):e18097
Journal of cellular and molecular medicine 2024 Feb;28(3):e18097
GK921, a transglutaminase inhibitor, strengthens the antitumor effect of cisplatin on pancreatic cancer cells by inhibiting epithelial-to-mesenchymal transition.
Li M, Wang X, Chen X, Hong J, Du Y, Song D
Biochimica et biophysica acta. Molecular basis of disease 2024 Feb;1870(2):166925
Biochimica et biophysica acta. Molecular basis of disease 2024 Feb;1870(2):166925
GIMAP7 inhibits epithelial-mesenchymal transition and glycolysis in lung adenocarcinoma cells via regulating the Smo/AMPK signaling pathway.
Cui L, Shen Y, Duan S, Ding Q, Wang Y, Yang W, Chen Y
Thoracic cancer 2024 Feb;15(4):286-298
Thoracic cancer 2024 Feb;15(4):286-298
M6A reader YTHDF1 promotes malignant progression of laryngeal squamous carcinoma through activating the EMT pathway by EIF4A3.
Guo H, Han Q, Guan X, Li Z, Wang Y, He L, Guo Y, Zhao L, Xue X, Liu H, Zhang C
Cellular signalling 2024 Feb;114:111002
Cellular signalling 2024 Feb;114:111002
Tumor suppressor miR-361-3p inhibits prostate cancer progression through Gli1 and AKT/mTOR signaling pathway.
Wang S, Huang X, Zhang G, Chen Z, Guan H, Zhou W
Cellular signalling 2024 Feb;114:110998
Cellular signalling 2024 Feb;114:110998
Biomimetic Nanomedicine Targeting Orchestrated Metabolism Coupled with Regulatory Factors to Disrupt the Metabolic Plasticity of Breast Cancer.
Meng L, Yang J, Gao Y, Cao Q, Jiang S, Xiao Y, Wang H, Liu W, Yuan A, Li Y, Huang H
ACS nano 2024 Feb 6;18(5):4360-4375
ACS nano 2024 Feb 6;18(5):4360-4375
SMG9 is a novel prognostic-related biomarker in glioma correlating with ferroptosis and immune infiltrates.
Dai Y, Zhang H, Feng S, Guo C, Tian W, Sun Y, Zhang Y
Heliyon 2024 Feb 29;10(4):e25716
Heliyon 2024 Feb 29;10(4):e25716
Novel prognostic marker TGFBI affects the migration and invasion function of ovarian cancer cells and activates the integrin αvβ3-PI3K-Akt signaling pathway.
Wang H, Xu YH, Guo Y
Journal of ovarian research 2024 Feb 23;17(1):50
Journal of ovarian research 2024 Feb 23;17(1):50
m6A-methylated KCTD21-AS1 regulates macrophage phagocytosis through CD47 and cell autophagy through TIPR.
Liang DM, Li YJ, Zhang JX, Shen HH, Wu CX, Xie N, Liang Y, Li YM, Xue JN, Sun HF, Wang Q, Yang J, Li XH, Wang PY, Xie SY
Communications biology 2024 Feb 21;7(1):215
Communications biology 2024 Feb 21;7(1):215
LncRNA RPARP-AS1 promotes the progression of osteosarcoma cells through regulating lipid metabolism.
Cai F, Liu L, Bo Y, Yan W, Tao X, Peng Y, Zhang Z, Liao Q, Yi Y
BMC cancer 2024 Feb 2;24(1):166
BMC cancer 2024 Feb 2;24(1):166
The clustering status of detached gastric cancer cells inhibits anoikis-induced ferroptosis to promote metastatic colonization.
Sun J, Li J, Pantopoulos K, Liu Y, He Y, Kang W, Ye X
Cancer cell international 2024 Feb 18;24(1):77
Cancer cell international 2024 Feb 18;24(1):77
Nuclear translocation of cleaved PCDH9 impairs gastric cancer metastasis by downregulating CDH2 expression.
Zhang Y, Zhu Y, Chen Y, Wang Y, Liu B, Pan Y, Liao X, Pan J, Gao H, Yang W, Yu G
iScience 2024 Feb 16;27(2):109011
iScience 2024 Feb 16;27(2):109011
N6-methyladenosine modification of B7-H3 mRNA promotes the development and progression of colorectal cancer.
Chen R, Su F, Zhang T, Wu D, Yang J, Guan Q, Chai C
iScience 2024 Feb 16;27(2):108956
iScience 2024 Feb 16;27(2):108956
Bromodomain containing 4 inhibition combats gastric precancerous lesions via modulating macrophage polarization.
Zhu L, Cai Q, Li G, Zou X
Tissue & cell 2024 Dec;91:102580
Tissue & cell 2024 Dec;91:102580
ALDH2 attenuates radiation-induced lung injury by inhibiting ROS and epithelial-mesenchymal transition mediated by the TGF-β1/Smad pathway.
Li E, Huang J, Huang J, Zhang F, Li C, Xia M, Li Z, Peng B, Liu Y, Ma J, Lei M
Pulmonary pharmacology & therapeutics 2024 Dec;87:102334
Pulmonary pharmacology & therapeutics 2024 Dec;87:102334
RSL3 sensitizes glioma cells to ionizing radiation by suppressing TGM2-dependent DNA damage repair and epithelial-mesenchymal transition.
Wang X, Shi W, Li M, Xin Y, Jiang X
Redox biology 2024 Dec;78:103438
Redox biology 2024 Dec;78:103438
SLMAP3 is essential for neurulation through mechanisms involving cytoskeletal elements, ABP, and PCP.
Rehmani T, Dias AP, Applin BD, Salih M, Tuana BS
Life science alliance 2024 Dec;7(12)
Life science alliance 2024 Dec;7(12)
CircRNA ITCH Inhibits Epithelial-Mesenchymal Transformation and Promotes Apoptosis in Papillary Thyroid Carcinoma via miR-106a-5p/JAZF1 Axis.
Chen Y, Lian Z, Zhang G, Lin Y, Zhang G, Liu W, Gao J, Zheng Z
Biochemical genetics 2024 Dec;62(6):4755-4769
Biochemical genetics 2024 Dec;62(6):4755-4769
Tabersonine enhances cisplatin sensitivity by modulating Aurora kinase A and suppressing epithelial-mesenchymal transition in triple-negative breast cancer.
Chen X, Yan Y, Liu Y, Yi Q, Xu Z
Pharmaceutical biology 2024 Dec;62(1):394-403
Pharmaceutical biology 2024 Dec;62(1):394-403
Adaptor protein CEMIP reduces the chemosensitivity of small cell lung cancer via activation of an SRC-YAP oncogenic module.
Shen XJ, Wei HL, Mo XC, Mo XX, Li L, He JC, Wei XY, Qin XJ, Xing SP, Luo Z, Chen ZQ, Yang J
Acta pharmacologica Sinica 2024 Dec;45(12):2657-2671
Acta pharmacologica Sinica 2024 Dec;45(12):2657-2671
Mediation of circ_0007142 on miR-128-3p/S100A14 pathway to stimulate the progression of cervical cancer.
Feng Q, Shen Z, Wang F, Shi C
Naunyn-Schmiedeberg's archives of pharmacology 2024 Dec;397(12):9919-9933
Naunyn-Schmiedeberg's archives of pharmacology 2024 Dec;397(12):9919-9933
Dihydroartemisinin enhances the anti-tumour effect of photodynamic therapy by targeting PKM2-mediated glycolysis in oesophageal cancer cell.
Jin M, Shi L, Wang L, Zhang D, Li Y
Journal of enzyme inhibition and medicinal chemistry 2024 Dec;39(1):2296695
Journal of enzyme inhibition and medicinal chemistry 2024 Dec;39(1):2296695
Circular RNA circWBSCR22 facilitates colorectal cancer metastasis by enhancing CHD4's protein stability.
Luo J, Xu S, Wang J, He L, Li Z
International journal of biological macromolecules 2024 Dec;282(Pt 4):137135
International journal of biological macromolecules 2024 Dec;282(Pt 4):137135
Integrative Analysis Identifies NSUN2 as an Essential Coordinator for Glioma Malignancy and Glucose Metabolism.
He Y, Yuan Y, Ji L, Shu Y, Wang Z, Zhang S, Yang W, Chen M, Liu Y
The journal of gene medicine 2024 Dec;26(12):e70004
The journal of gene medicine 2024 Dec;26(12):e70004
Quercetin inhibits malignant progression of high metastatic advanced colon cancer in hypoxia via suppressing ROS and PI3K/AKT pathway.
Shang P, Yang J, Shao L, Sun C, Ji J, Wang X, Zheng Z, Guo X
Pharmaceutical science advances 2024 Dec;2:100057
Pharmaceutical science advances 2024 Dec;2:100057
Cardiac Fibroblasts Enhance MMP2 Activity to Suppress Gap Junction Function in Cardiomyocytes.
Bai X, Huang X, Yi J, Yan X, Hu T, Wang L, Wang Z, Gao H
Applied biochemistry and biotechnology 2024 Dec;196(12):8493-8512
Applied biochemistry and biotechnology 2024 Dec;196(12):8493-8512
Corynoxine exerts the anti-tumor effect on esophageal squamous cell carcinoma principally via the EZH2-DUSP5-ERK1/2-mediated cell growth inhibition.
Huang G, Xu J, Li Y, Song L, Wen C, Ruan Q, Wen Z, Qi J, Deng J, Liu Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156103
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156103
Targeting and degradation of OTUB1 by Erianin for antimetastasis in esophageal squamous cell carcinoma.
Zhu Y, Kang N, Zhang L, Tao J, Xue W, Li H, Li Y, Zheng X, He W, Ma J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:155969
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:155969
RRM2 Regulates Hepatocellular Carcinoma Progression Through Activation of TGF-β/Smad Signaling and Hepatitis B Virus Transcription.
Wu D, Sun X, Li X, Zuo Z, Yan D, Yin W
Genes 2024 Dec 6;15(12)
Genes 2024 Dec 6;15(12)
High-fat diet led to testicular inflammation and ferroptosis via dysbiosis of gut microbes.
Zhang Z, Chen H, Li Q
International immunopharmacology 2024 Dec 5;142(Pt B):113235
International immunopharmacology 2024 Dec 5;142(Pt B):113235
Mechanistic study of quercetin in the treatment of hepatocellular carcinoma with diabetes via MEK/ERK pathway.
Lin F, Zhou W, Yuan X, Liu S, He Z
International immunopharmacology 2024 Dec 5;142(Pt B):113194
International immunopharmacology 2024 Dec 5;142(Pt B):113194
Activin A inhibits the migration of human lung adenocarcinoma A549 cells induced by EGF.
Zhang F, Cui X, Yang K, Guo R, Zhu L, Zhao W, Liu Z, Liu B
International immunopharmacology 2024 Dec 5;142(Pt B):113170
International immunopharmacology 2024 Dec 5;142(Pt B):113170
Serine related gene CCT6A promotes metastasis of hepatocellular carcinoma via interacting with RPS3.
Cui H, Jiang L, Zhou Y, Zhou Y, Li F, Zhang Z
Functional & integrative genomics 2024 Dec 4;24(6):225
Functional & integrative genomics 2024 Dec 4;24(6):225
Tripartite motif-containing protein 50 suppresses triple-negative breast cancer progression by regulating the epithelial-mesenchymal transition.
Chen D, Jiang J, Zhang W, Li X, Ge Q, Liu X, Li X
Cancer biology & therapy 2024 Dec 31;25(1):2427410
Cancer biology & therapy 2024 Dec 31;25(1):2427410
RND1 inhibits epithelial-mesenchymal transition and temozolomide resistance of glioblastoma via AKT/GSK3-β pathway.
Sun Q, Xu J, Yuan F, Liu Y, Chen Q, Guo L, Dong H, Liu B
Cancer biology & therapy 2024 Dec 31;25(1):2321770
Cancer biology & therapy 2024 Dec 31;25(1):2321770
DNMT1-driven methylation of RORA facilitates esophageal squamous cell carcinoma progression under hypoxia through SLC2A3.
Yao W, Shang L, Wang Y, Xu L, Bai Y, Feng M, Jia X, Wu S
Journal of translational medicine 2024 Dec 31;22(1):1167
Journal of translational medicine 2024 Dec 31;22(1):1167
Macropinocytosis inhibits alkaliptosis in pancreatic cancer cells through fatty acid uptake.
Chen F, Tang H, Lin J, Xiang L, Lu Y, Kang R, Tang D, Liu J
Carcinogenesis 2024 Dec 30;45(12):953-964
Carcinogenesis 2024 Dec 30;45(12):953-964
Regulation of a novel circATP8B4/miR-31-5p/nestin ceRNA crosstalk in proliferation, motility, invasion and radiosensitivity of human glioma cells.
Luo D, Luo A, Ye G, Li D, Hu S, Zhao H, Peng B
Journal of radiation research 2024 Dec 3;65(6):752-764
Journal of radiation research 2024 Dec 3;65(6):752-764
Exosomes containing circSCP2 in colorectal cancer promote metastasis via sponging miR-92a-1-5p and interacting with PTBP1 to stabilize IGF2BP1.
Meng Q, Xiang H, Wang Y, Hu K, Luo X, Wang J, Chen E, Zhang W, Chen J, Chen X, Wang H, Ju Z, Song Z
Biology direct 2024 Dec 20;19(1):130
Biology direct 2024 Dec 20;19(1):130
Machine learning-based prognostic model of lactylation-related genes for predicting prognosis and immune infiltration in patients with lung adenocarcinoma.
Gao M, Wang M, Zhou S, Hou J, He W, Shu Y, Wang X
Cancer cell international 2024 Dec 18;24(1):400
Cancer cell international 2024 Dec 18;24(1):400
Alleviating role of ketamine in breast cancer cell-induced osteoclastogenesis and tumor bone metastasis-induced bone cancer pain through an SRC/EGR1/CST6 axis.
Zhang X, Zhang Y, Du W
BMC cancer 2024 Dec 18;24(1):1535
BMC cancer 2024 Dec 18;24(1):1535
miR-3191 promotes the proliferation and metastasis of hepatocellular carcinoma via regulating PAK6.
Xie A, Wang H, Huang J, Sun M, Chen L
Infectious agents and cancer 2024 Dec 18;19(1):64
Infectious agents and cancer 2024 Dec 18;19(1):64
Has_circ_0002360 facilitates immune evasion by enhancing heterogeneous nuclear ribonucleoprotein A1 stability, thereby promoting malignant progression in non-small cell lung cancer.
Fan J, Xue L, Lu R, Liu J, Luo J
Experimental cell research 2024 Dec 1;443(2):114312
Experimental cell research 2024 Dec 1;443(2):114312
TGFβ2 mediates oxidative stress-induced epithelial-to-mesenchymal transition of bladder smooth muscle.
Geng J, Zhang X, Zhang Y, Meng X, Sun J, Zhou B, Ma J
In vitro cellular & developmental biology. Animal 2024 Aug;60(7):793-804
In vitro cellular & developmental biology. Animal 2024 Aug;60(7):793-804
Dexmedetomidine promotes colorectal cancer progression via Piwil2 signaling.
Dong J, Che J, Wu Y, Deng Y, Jiang X, He Z, Zhang J
Cellular oncology (Dordrecht, Netherlands) 2024 Aug;47(4):1459-1474
Cellular oncology (Dordrecht, Netherlands) 2024 Aug;47(4):1459-1474
IFIT1 modulates the proliferation, migration and invasion of pancreatic cancer cells via Wnt/β-catenin signaling.
Li TH, Zhao BB, Qin C, Wang YY, Li ZR, Cao HT, Yang XY, Zhou XT, Wang WB
Cellular oncology (Dordrecht, Netherlands) 2024 Aug;47(4):1253-1265
Cellular oncology (Dordrecht, Netherlands) 2024 Aug;47(4):1253-1265
N6-methyladenosine modified circPAK2 promotes lymph node metastasis via targeting IGF2BPs/VEGFA signaling in gastric cancer.
Ding P, Wu H, Wu J, Li T, He J, Ju Y, Liu Y, Li F, Deng H, Gu R, Zhang L, Guo H, Tian Y, Yang P, Meng N, Li X, Guo Z, Meng L, Zhao Q
Oncogene 2024 Aug;43(34):2548-2563
Oncogene 2024 Aug;43(34):2548-2563
Autocatalytic, Brain Tumor-Targeting Delivery of Bardoxolone Methyl Self-Assembled Nanoparticles for Glioblastoma Treatment.
Ye Z, Sheu WC, Qu H, Peng B, Liu J, Zhang L, Yuan F, Wei Y, Zhou J, Chen Q, Xiao X, Zhang S
Small science 2024 Aug;4(8):2400081
Small science 2024 Aug;4(8):2400081
Biological effect of ETV4 and the underlying mechanism of its regulatory effect on epithelial‑mesenchymal transition in intrahepatic cholangiocarcinoma cells.
Liu L, Feng Y, Xiang X, Xu M, Tang G
Oncology letters 2024 Aug;28(2):346
Oncology letters 2024 Aug;28(2):346
Exosomal miR-130b-3p suppresses metastasis of non-small cell lung cancer cells by targeting DEPDC1 via TGF-β signaling pathway.
Lv M, Li X, Zheng C, Tian W, Yang H, Yin Z, Zhou B
International journal of biological macromolecules 2024 Aug;275(Pt 1):133594
International journal of biological macromolecules 2024 Aug;275(Pt 1):133594
P4HA3 promotes head and neck squamous cell carcinoma progression via the WNT/β-catenin signaling pathway.
Wang Q, Meng D, Shen S, Cao Y, Zhang P, Liu Y, Du L, Li H, Shao C, Dong Q
Pathology, research and practice 2024 Aug;260:155481
Pathology, research and practice 2024 Aug;260:155481
INPP4B suppresses HER2-induced mesenchymal transition in HER2+ breast cancer and enhances sensitivity to Lapatinib.
Qu N, Wang G, Su Y, Chen B, Zhou D, Wu Y, Yuan L, Yin M, Liu M, Peng Y, Zhou W
Biochemical pharmacology 2024 Aug;226:116347
Biochemical pharmacology 2024 Aug;226:116347
Integrated multi-omics profiling landscape of organising pneumonia.
Tang Y, Chu C, Bu S, Sun Q, Liu A, Xie J, Qiao S, Huang L, Wang H
Clinical and translational medicine 2024 Aug;14(8):e1782
Clinical and translational medicine 2024 Aug;14(8):e1782
TAGLN2 targeted control of ARPC5-mediated activation of the MEK/ERK signaling pathway influences the proliferation, invasion, and metastasis of pancreatic cancer cells.
Gao Y, Hou J, Fei X, Ren L, Lu R, Liu P, Liu S, Zhu C, Wang X, Pan Y
Cellular signalling 2024 Aug;120:111227
Cellular signalling 2024 Aug;120:111227
An Inherited Allele Confers Prostate Cancer Progression and Drug Resistance via RFX6/HOXA10-Orchestrated TGFβ Signaling.
Zhong M, Xu W, Tian P, Zhang Q, Wang Z, Liang L, Zhang Q, Yang Y, Lu Y, Wei GH
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(32):e2401492
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(32):e2401492
Aloperine Suppresses Cancer Progression by Interacting with VPS4A to Inhibit Autophagosome-lysosome Fusion in NSCLC.
Guo W, Zhou H, Wang J, Lu J, Dong Y, Kang Z, Qiu X, Ouyang X, Chen Q, Li J, Cheng X, Du K, Li M, Lin Z, Jin M, Zhang L, Sarapultsev A, Shi K, Li F, Zhang G, Wu K, Rong Y, Heissmeyer V, Liu Y, Li Y, Huang K, Luo S, Hu D
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(31):e2308307
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(31):e2308307
STC2 suppresses triple-negative breast cancer migration and invasion by inhibition on EMT and promotion on cell apoptosis.
Lei R, Yao C, Huang R, Wu W, Ou L, Yang C
Discover oncology 2024 Aug 9;15(1):339
Discover oncology 2024 Aug 9;15(1):339
TCF12-regulated GRB7 facilitates the HER2+ breast cancer progression by activating Notch1 signaling pathway.
Wang G, Wu Y, Su Y, Qu N, Chen B, Zhou D, Yuan L, Yin M, Liu M, Zhou W
Journal of translational medicine 2024 Aug 7;22(1):745
Journal of translational medicine 2024 Aug 7;22(1):745
Hypoxia exacerbates the malignant transformation of gastric epithelial cells induced by long-term H. pylori infection.
He Y, Zhang X, Zhang X, Fu B, Xing J, Fu R, Lv J, Guo M, Huo X, Liu X, Lu J, Cao L, Du X, Ge Z, Chen Z, Lu X, Li C
Microbiology spectrum 2024 Aug 6;12(8):e0031124
Microbiology spectrum 2024 Aug 6;12(8):e0031124
OTU deubiquitinase, ubiquitin aldehyde binding 2 (OTUB2) modulates the stemness feature, chemoresistance, and epithelial-mesenchymal transition of colon cancer via regulating GINS complex subunit 1 (GINS1) expression.
Zhu W, Wu C, Liu Z, Zhao S, Huang J
Cell communication and signaling : CCS 2024 Aug 29;22(1):420
Cell communication and signaling : CCS 2024 Aug 29;22(1):420
Capsaicin combined with cisplatin inhibits TGF-β1-induced EMT and TSCC cells migration via the Claudin-1/PI3K/AKT/mTOR signaling pathway.
Li Z, Zhao Q, Liu X, Zhou X, Wang Y, Zhao M, Wu F, Zhao G, Guo X
Cancer cell international 2024 Aug 28;24(1):300
Cancer cell international 2024 Aug 28;24(1):300
Acetylation of PGK1 at lysine 323 promotes glycolysis, cell proliferation, and metastasis in luminal A breast cancer cells.
Gao X, Pan T, Gao Y, Zhu W, Liu L, Duan W, Han C, Feng B, Yan W, Song Q, Liu Y, Yue L
BMC cancer 2024 Aug 27;24(1):1054
BMC cancer 2024 Aug 27;24(1):1054
TRIP13 regulates progression of gastric cancer through stabilising the expression of DDX21.
Zhang G, Yang R, Wang B, Yan Q, Zhao P, Zhang J, Su W, Yang L, Cui H
Cell death & disease 2024 Aug 26;15(8):622
Cell death & disease 2024 Aug 26;15(8):622
Catalpol inhibits HHcy-induced EndMT in endothelial cells by modulating ROS/NF-κB signaling.
Wu C, Li Y, Liu S, Wang L, Wang X
BMC cardiovascular disorders 2024 Aug 16;24(1):431
BMC cardiovascular disorders 2024 Aug 16;24(1):431
Does rAj-Tspin, a novel peptide from A. japonicus, exert antihepatocellular carcinoma effects via the ITGB1/ZYX/FAK/AKT signaling pathway?
Che Y, Lu X, Wang X, Liu Z, Guan L, Li X, Du Z, Ren H, Wang J, Zhou Z, Lv L
Cancer cell international 2024 Aug 14;24(1):290
Cancer cell international 2024 Aug 14;24(1):290
Pt(iv) derivatives of cisplatin and oxaliplatin bearing an EMT-related TMEM16A/COX-2-selective dual inhibitor against colorectal cancer cells HCT116.
Ma ZY, Ding XJ, Zhu ZZ, Chen Q, Wang DB, Qiao X, Xu JY
RSC medicinal chemistry 2024 Aug 1;15(9):3239-47
RSC medicinal chemistry 2024 Aug 1;15(9):3239-47
RAE1 promotes gastric carcinogenesis and epithelial-mesenchymal transition.
Dong W, Li X, Cheng L, Yang J, Zhao Z, Qiang X, Li P, Wu J, Guo L
Archives of biochemistry and biophysics 2024 Apr;754:109896
Archives of biochemistry and biophysics 2024 Apr;754:109896
Campothecin suppresses cell proliferation and migration in head and neck squamous cell carcinoma by blocking RAB27A-mediated phosphatidylinositol 3 kinase (PI3K)/protein kinase B (AKT) pathway.
Zhao Y, Wang Y, Zhao L, Qu L, Zheng JH
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2024 Apr;75(2):205-213
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2024 Apr;75(2):205-213
Kinesin Family Member-18A (KIF18A) Promotes Cell Proliferation and Metastasis in Hepatocellular Carcinoma.
Ren J, Yao X, Yang M, Cheng S, Wu D, Xu K, Li R, Zhang H, Zhang D
Digestive diseases and sciences 2024 Apr;69(4):1274-1286
Digestive diseases and sciences 2024 Apr;69(4):1274-1286
Bone morphogenetic protein 6 (BMP6) antagonises experimental proliferative vitreoretinopathy established by TGF-β2 stimulation in retinal pigment epithelial cells through modulation of the p38 and JNK MAPK pathways.
Liu X, Liu M, Chen L
Cell and tissue research 2024 Apr;396(1):103-117
Cell and tissue research 2024 Apr;396(1):103-117
Propofol-induced LINC01133 inhibits the progression of colorectal cancer via miR-186-5p/NR3C2 axis.
Yao Y, Zhang F, Liu F, Xia D
Environmental toxicology 2024 Apr;39(4):2265-2284
Environmental toxicology 2024 Apr;39(4):2265-2284
FERMT2 upregulation in CAFs enhances EMT of OSCC and M2 macrophage polarization.
Ma X, Zhao D, Liu S, Zuo J, Wang W, Wang F, Li Y, Ding Z, Wang J, Wang X
Oral diseases 2024 Apr;30(3):991-1003
Oral diseases 2024 Apr;30(3):991-1003
CHL1 inhibits cell proliferation, migration and invasion by regulating the NF‑κB signaling pathway in colorectal cancer.
Bao M, Li S, Zhu Y, Dong X, Wang R, Jing F
Experimental and therapeutic medicine 2024 Apr;27(4):165
Experimental and therapeutic medicine 2024 Apr;27(4):165
TGF-β2-induced alterations of m6A methylation in hTERT RPE-1 cells.
Li X, Zhao X, Yin R, Yuan M, Zhang Y, Li X
Experimental eye research 2024 Apr;241:109839
Experimental eye research 2024 Apr;241:109839
A pyrazolopyridine as a novel AhR signaling activator with anti-breast cancer properties in vitro and in vivo.
Abduh MS, Alwassil OI, Aldaqal SM, Alfwuaires MA, Farhan M, Hanieh H
Biochemical pharmacology 2024 Apr;222:116079
Biochemical pharmacology 2024 Apr;222:116079
RETRACTED: High PGC-1α Expression as a Poor Prognostic Indicator in Intracranial Glioma.
Cheng YW, Lee JH, Chang CH, Tseng TT, Chai CY, Lieu AS, Kwan AL
Biomedicines 2024 Apr 29;12(5)
Biomedicines 2024 Apr 29;12(5)
Tabersonine Enhances Olaparib Sensitivity through FHL1-Mediated Epithelial-Mesenchymal Transition in an Ovarian Tumor.
Chen X, Yan Y, Liu Y, Yi Q, Xu Z
Journal of natural products 2024 Apr 26;87(4):837-848
Journal of natural products 2024 Apr 26;87(4):837-848
DCDC2 inhibits hepatic stellate cell activation and ameliorates CCl(4)-induced liver fibrosis by suppressing Wnt/β-catenin signaling.
Liu QQ, Chen J, Ma T, Huang W, Lu CH
Scientific reports 2024 Apr 24;14(1):9425
Scientific reports 2024 Apr 24;14(1):9425
Targeting high circDNA2v levels in colorectal cancer induces cellular senescence and elicits an anti-tumor secretome.
Wu S, Dai X, Xia Y, Zhao Q, Zhao H, Shi Z, Yin X, Liu X, Zhang A, Yao Z, Zhang H, Li Q, Thorne RF, Zhang S, Sheng W, Hu W, Gu H
Cell reports 2024 Apr 23;43(4):114111
Cell reports 2024 Apr 23;43(4):114111
N6-methyladenosine-modified circSLCO1B3 promotes intrahepatic cholangiocarcinoma progression via regulating HOXC8 and PD-L1.
Li J, Xu X, Xu K, Zhou X, Wu K, Yao Y, Liu Z, Chen C, Wang L, Sun Z, Jiao D, Han X
Journal of experimental & clinical cancer research : CR 2024 Apr 20;43(1):119
Journal of experimental & clinical cancer research : CR 2024 Apr 20;43(1):119
The NF-κB/NUAK2 signaling axis regulates pancreatic cancer progression by targeting SMAD2/3.
Wang R, Su D, Liu Y, Huang H, Qiu J, Cao Z, Yang G, Chen H, Luo W, Tao J, Weng G, Zhang T
iScience 2024 Apr 19;27(4):109406
iScience 2024 Apr 19;27(4):109406
PRMT6-mediated transcriptional activation of ythdf2 promotes glioblastoma migration, invasion, and emt via the wnt-β-catenin pathway.
Yu P, Xu T, Ma W, Fang X, Bao Y, Xu C, Huang J, Sun Y, Li G
Journal of experimental & clinical cancer research : CR 2024 Apr 18;43(1):116
Journal of experimental & clinical cancer research : CR 2024 Apr 18;43(1):116
Activation of the YY1-UGT2B7 Axis Promotes Mammary Estrogen Homeostasis Dysregulation and Exacerbates Breast Tumor Metastasis.
Xu J, Zhou Y, He S, Wang Y, Ma J, Li C, Liu Z, Zhou X
Drug metabolism and disposition: the biological fate of chemicals 2024 Apr 16;52(5):408-421
Drug metabolism and disposition: the biological fate of chemicals 2024 Apr 16;52(5):408-421
hsa_circ_0007919 promotes pancreatic cancer metastasis by modulating Sp1-mediated THBS1 transcription.
Ma X, Xu L, Gong S, Wu N, Guo J, Feng X, Zhao M, Qiu S, Sun M, Zhang C, Zhang X, Ren Z, Zhang P
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Apr 15;38(7):e23591
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Apr 15;38(7):e23591
Hawthorn Proanthocyanidin Extract Inhibits Colorectal Carcinoma Metastasis by Targeting the Epithelial-Mesenchymal Transition Process and Wnt/β-Catenin Signaling Pathway.
Wang Z, Sun Y, Wu M, Zhou L, Zheng Y, Ren T, Li M, Zhao W
Foods (Basel, Switzerland) 2024 Apr 12;13(8)
Foods (Basel, Switzerland) 2024 Apr 12;13(8)
Combined therapy of dabrafenib and an anti-HER2 antibody-drug conjugate for advanced BRAF-mutant melanoma.
Li W, Zheng C, Xu X, Xia Y, Zhang K, Huang A, Zhang X, Zheng Y, Chen G, Zhang S
Cellular & molecular biology letters 2024 Apr 10;29(1):50
Cellular & molecular biology letters 2024 Apr 10;29(1):50
Adhesive hydrogel releases protocatechualdehyde-Fe(3+) complex to promote three healing stages for accelerated therapy of oral ulcers.
Wang Y, Pan Z, Cui J, Zhang X, Li D, Sun H, Yang B, Li Y
Acta biomaterialia 2024 Apr 1;178:68-82
Acta biomaterialia 2024 Apr 1;178:68-82
CircGPC3 promotes hepatocellular carcinoma progression and metastasis by sponging miR-578 and regulating RAB7A/PSME3 expression.
Ju L, Luo Y, Cui X, Zhang H, Chen L, Yao M
Scientific reports 2024 Apr 1;14(1):7632
Scientific reports 2024 Apr 1;14(1):7632
Up-regulated SPP1 increases the risk from IPF to lung cancer via activating the pro-tumor macrophages.
Chen T, Guo J, Ai L, Wang Y, Wang Y, Chen B, Liu M, Zhuang S, Liu K, Zhao Z, Liang H, Gu Y
Computational and structural biotechnology journal 2023;21:5751-5764
Computational and structural biotechnology journal 2023;21:5751-5764
The Role of Purine Metabolism-Related Genes PPAT and IMPDH1 in the Carcinogenesis of Intrahepatic Cholangiocarcinoma Based on Metabonomic and Bioinformatic Analyses.
Liu CJ, Ma ZZ, Gong WZ, Mao XH, Wen HQ, Wang XH
Journal of oncology 2023;2023:5141836
Journal of oncology 2023;2023:5141836
LncRNA SNHG5 Suppresses Cell Migration and Invasion of Human Lung Adenocarcinoma via Regulation of Epithelial-Mesenchymal Transition.
Li Z, Wu Y, Zhang C, Dai S, Wei S, Zhao R, Gao F, Zhao L, Shan B
Journal of oncology 2023;2023:3335959
Journal of oncology 2023;2023:3335959
Lnc NR2F1-AS1 Promotes Breast Cancer Metastasis by Targeting the MiR-25-3p/ZEB2 Axis.
Zhai D, Zhou Y, Kuang X, Shao F, Zhen T, Lin Y, Wang Q, Shao N
International journal of medical sciences 2023;20(9):1152-1162
International journal of medical sciences 2023;20(9):1152-1162
Low Expression of GIGYF1 Inhibits Metastasis, Proliferation, and Promotes Apoptosis and Autophagy of Gastric Cancer Cells.
Zhu L, Yao Z, Luo Q, Liu Y, Zhao W, Shao C, Shao S, Cui F
International journal of medical sciences 2023;20(8):1038-1045
International journal of medical sciences 2023;20(8):1038-1045
PYGL-mediated glucose metabolism reprogramming promotes EMT phenotype and metastasis of pancreatic cancer.
Ji Q, Li H, Cai Z, Yuan X, Pu X, Huang Y, Fu S, Chu L, Jiang C, Xue J, Zhang X, Li R
International journal of biological sciences 2023;19(6):1894-1909
International journal of biological sciences 2023;19(6):1894-1909
Timosaponin AIII promotes non-small-cell lung cancer ferroptosis through targeting and facilitating HSP90 mediated GPX4 ubiquitination and degradation.
Zhou C, Yu T, Zhu R, Lu J, Ouyang X, Zhang Z, Chen Q, Li J, Cui J, Jiang F, Jin KY, Sarapultsev A, Li F, Zhang G, Luo S, Hu D
International journal of biological sciences 2023;19(5):1471-1489
International journal of biological sciences 2023;19(5):1471-1489
System analysis identifies UBE2C as a novel oncogene target for adrenocortical carcinoma.
Huang R, Guo L, Chen C, Xiang Y, Li G, Zheng J, Wu Y, Yuan X, Zhou J, Gao W, Xiang S
PloS one 2023;18(8):e0289418
PloS one 2023;18(8):e0289418
Downregulation of KIAA1199 alleviated the activation, proliferation, and migration of hepatic stellate cells by the inhibition of epithelial-mesenchymal transition.
Liu J, Xia S, Han P, Zhang M, Wu J, Liao J
Open medicine (Warsaw, Poland) 2023;18(1):20230689
Open medicine (Warsaw, Poland) 2023;18(1):20230689
HDAC5-mediated PRAME regulates the proliferation, migration, invasion, and EMT of laryngeal squamous cell carcinoma via the PI3K/AKT/mTOR signaling pathway.
Yu L, Cao H, Yang JW, Meng WX, Yang C, Wang JT, Yu MM, Wang BS
Open medicine (Warsaw, Poland) 2023;18(1):20230665
Open medicine (Warsaw, Poland) 2023;18(1):20230665
Exosome-Delivered circSTAU2 Inhibits the Progression of Gastric Cancer by Targeting the miR-589/CAPZA1 Axis.
Zhang C, Wei G, Zhu X, Chen X, Ma X, Hu P, Liu W, Yang W, Ruan T, Zhang W, Wu C, Tao K
International journal of nanomedicine 2023;18:127-142
International journal of nanomedicine 2023;18:127-142
Escherichia coli Promotes Endothelial to Mesenchymal Transformation of Liver Sinusoidal Endothelial Cells and Exacerbates Nonalcoholic Fatty Liver Disease Via Its Flagellin.
Shen B, Gu T, Shen Z, Zhou C, Guo Y, Wang J, Li B, Xu X, Li F, Zhang Q, Cai X, Dong H, Lu L
Cellular and molecular gastroenterology and hepatology 2023;16(6):857-879
Cellular and molecular gastroenterology and hepatology 2023;16(6):857-879
B7 Induces Apoptosis in Colorectal Cancer Cells by Regulating the Expression of Caspase-3 and Inhibits Autophagy.
Zhang X, Li F, Li R, Zhao N, Liu D, Xu Y, Wang L, Wang D, Zhao R
OncoTargets and therapy 2023;16:867-883
OncoTargets and therapy 2023;16:867-883
The cancer/testis antigen HORMAD1 promotes gastric cancer progression by activating the NF-κB signaling pathway and inducing epithelial-mesenchymal transition.
Bian G, Li W, Huang D, Zhang Q, Ding X, Zang X, Ye Y, Cao J, Li P
American journal of translational research 2023;15(9):5808-5825
American journal of translational research 2023;15(9):5808-5825
Mannan-Binding Lectin Reduces Epithelial-Mesenchymal Transition in Pulmonary Fibrosis via Inactivating the Store-Operated Calcium Entry Machinery.
Liu Y, Xie X, Wang P, Luo J, Chen Y, Xu Q, Zhou J, Lu X, Zhao J, Chen Z, Zuo D
Journal of innate immunity 2023;15(1):37-49
Journal of innate immunity 2023;15(1):37-49
ALKBH5-PYCR2 Positive Feedback Loop Promotes Proneural-Mesenchymal Transition Via Proline Synthesis In GBM.
Li L, Yang M, Pu X, Tang Y, Fei F, Li Z, Hou H, Chen Q, Wang Q, Wu Y, Zhang Y, Ren C, Gong A
Journal of Cancer 2023;14(9):1579-1591
Journal of Cancer 2023;14(9):1579-1591
LncRNA HOTAIR Enhances Epithelial-to-mesenchymal Transition to Promote the Migration and Invasion of Liver Cancer by Regulating NUAK1 via Epigenetic Inhibition miR-145-5p Expression.
Chu DX, Jin Y, Wang BR, Jiao Y, Zhang CK, Guo ZH, Hu SZ, Li N
Journal of Cancer 2023;14(12):2329-2343
Journal of Cancer 2023;14(12):2329-2343
High SGO2 predicted poor prognosis and high therapeutic value of lung adenocarcinoma and promoted cell proliferation, migration, invasion, and epithelial-to-mesenchymal transformation.
Wu Z, Zhuo T, Li Z, Zhu Y, Wu J, Liang G, Dai L, Wang Y, Tan X, Chen M
Journal of Cancer 2023;14(12):2301-2314
Journal of Cancer 2023;14(12):2301-2314
APOC1 exacerbates renal fibrosis through the activation of the NF-κB signaling pathway in IgAN.
Yu K, Ding L, An X, Yang Y, Zhang X, Li L, Wang C, Bai F, Yang X
Frontiers in pharmacology 2023;14:1181435
Frontiers in pharmacology 2023;14:1181435
A novel prognostic signatures based on metastasis- and immune-related gene pairs for colorectal cancer.
Pan B, Yue Y, Ding W, Sun L, Xu M, Wang S
Frontiers in immunology 2023;14:1161382
Frontiers in immunology 2023;14:1161382
Exploration of epithelial-mesenchymal transition-related lncRNA signature and drug sensitivity in breast cancer.
Li C, Zheng L, Xu G, Yuan Q, Di Z, Yang Y, Dong X, Hou J, Wu G
Frontiers in endocrinology 2023;14:1154741
Frontiers in endocrinology 2023;14:1154741
Apolipoprotein A-I attenuates peritoneal fibrosis associated with peritoneal dialysis by inhibiting oxidative stress and inflammation.
Lu J, Gao J, Sun J, Wang H, Sun H, Huang Q, Zhang Y, Zhong S
Frontiers in pharmacology 2023;14:1106339
Frontiers in pharmacology 2023;14:1106339
NPM1 promotes nasopharyngeal carcinoma metastasis and stemness by recruiting Mdm2 to induce the ubiquitination-mediated degradation of p53.
Hu L, Gong P, Zhou N, Wang S, He C, Zhou Y, Li Q, Zhao X, Peng H
American journal of cancer research 2023;13(5):1766-1785
American journal of cancer research 2023;13(5):1766-1785
ZY-444 inhibits the growth and metastasis of prostate cancer by targeting TNFAIP3 through TNF signaling pathway.
Han MT, Pei H, Sun QQ, Wang CL, Li P, Xie YY, Cao LJ, Zhang XX, Sun ZL
American journal of cancer research 2023;13(4):1533-1546
American journal of cancer research 2023;13(4):1533-1546
Tocilizumab (monoclonal anti-IL-6R antibody) reverses anlotinib resistance in osteosarcoma.
Xu J, Chen C, Sun K, Shi Q, Wang B, Huang Y, Ren T, Tang X
Frontiers in oncology 2023;13:1192472
Frontiers in oncology 2023;13:1192472
The deubiquitinating enzyme MINDY2 promotes pancreatic cancer proliferation and metastasis by stabilizing ACTN4 expression and activating the PI3K/AKT/mTOR signaling pathway.
Liu P, Liu S, Zhu C, Li Y, Li Y, Fei X, Hou J, Wang X, Pan Y
Frontiers in oncology 2023;13:1169833
Frontiers in oncology 2023;13:1169833
System analysis based on the migration- and invasion-related gene sets identifies the infiltration-related genes of glioma.
Shi S, Zhong J, Peng W, Yin H, Zhong D, Cui H, Sun X
Frontiers in oncology 2023;13:1075716
Frontiers in oncology 2023;13:1075716
EXOSC10 is a novel hepatocellular carcinoma prognostic biomarker: a comprehensive bioinformatics analysis and experiment verification.
Meng ZY, Fan YC, Zhang CS, Zhang LL, Wu T, Nong MY, Wang T, Chen C, Jiang LH
PeerJ 2023;11:e15860
PeerJ 2023;11:e15860
VIRMA facilitates intrahepatic cholangiocarcinoma progression through epigenetic augmentation of TMED2 and PARD3B mRNA stabilization.
Xu H, Lin X, Li Z, He X, Li Y, Qiu L, Lu L, Liu B, Zhan M, He K
Journal of gastroenterology 2023 Sep;58(9):925-944
Journal of gastroenterology 2023 Sep;58(9):925-944
Estrogens drive the endoplasmic reticulum-associated degradation and promote proto-oncogene c-Myc expression in prostate cancer cells by androgen receptor/estrogen receptor signaling.
Erzurumlu Y, Dogan HK, Catakli D, Aydogdu E, Muhammed MT
Journal of cell communication and signaling 2023 Sep;17(3):793-811
Journal of cell communication and signaling 2023 Sep;17(3):793-811
ACSL4 promotes ferroptosis and M1 macrophage polarization to regulate the tumorigenesis of nasopharyngeal carcinoma.
Chen P, Wang D, Xiao T, Gu W, Yang H, Yang M, Wang H
International immunopharmacology 2023 Sep;122:110629
International immunopharmacology 2023 Sep;122:110629
Stiff Substrate Induces Nucleus Pulposus Cell Ferroptosis via YAP and N-Cadherin Mediated Mechanotransduction.
Ke W, Liao Z, Liang H, Tong B, Song Y, Li G, Ma L, Wang K, Feng X, Li S, Hua W, Wang B, Yang C
Advanced healthcare materials 2023 Sep;12(23):e2300458
Advanced healthcare materials 2023 Sep;12(23):e2300458
Royal jelly acid suppresses hepatocellular carcinoma tumorigenicity by inhibiting H3 histone lactylation at H3K9la and H3K14la sites.
Xu H, Li L, Wang S, Wang Z, Qu L, Wang C, Xu K
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154940
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154940
Calycosin inhibits triple-negative breast cancer progression through down-regulation of the novel estrogen receptor-α splice variant ER-α30-mediated PI3K/AKT signaling pathway.
Li Y, Hu S, Chen Y, Zhang X, Gao H, Tian J, Chen J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154924
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154924
GART Functions as a Novel Methyltransferase in the RUVBL1/β-Catenin Signaling Pathway to Promote Tumor Stemness in Colorectal Cancer.
Tang C, Ke M, Yu X, Sun S, Luo X, Liu X, Zhou Y, Wang Z, Cui X, Gu C, Yang Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Sep;10(25):e2301264
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Sep;10(25):e2301264
CBX3 promotes clear cell renal carcinoma through PI3K/AKT activation and aberrant immunity.
Chen J, Lin Y, Zheng S, Chen Q, Tang S, Zhong X
Journal of translational medicine 2023 Sep 6;21(1):600
Journal of translational medicine 2023 Sep 6;21(1):600
Pleckstrin-2 promotes tumour immune escape from NK cells by activating the MT1-MMP-MICA signalling axis in gastric cancer.
Mao D, Zhou Z, Chen H, Liu X, Li D, Chen X, He Y, Liu M, Zhang C
Cancer letters 2023 Sep 28;572:216351
Cancer letters 2023 Sep 28;572:216351
Long non-coding RNA MIDEAS-AS1 inhibits growth and metastasis of triple-negative breast cancer via transcriptionally activating NCALD.
Luo D, Liang Y, Wang Y, Ye F, Jin Y, Li Y, Han D, Wang Z, Chen B, Zhao W, Wang L, Chen X, Jiang L, Yang Q
Breast cancer research : BCR 2023 Sep 28;25(1):109
Breast cancer research : BCR 2023 Sep 28;25(1):109
DKK1 Promotes Epithelial-Mesenchymal Transition and Cisplatin Resistance in Gastric Cancer via Activation of the PI3K/AKT Pathway.
Li J, Zhang Y, Ye F, Qian P, Qin Z, Li D, Ye L, Feng L
Cancers 2023 Sep 27;15(19)
Cancers 2023 Sep 27;15(19)
E-Cadherin Is Expressed in Epithelial Cells of the Choroid Plexus in Human and Mouse Brains.
Takebayashi G, Chiba Y, Wakamatsu K, Murakami R, Miyai Y, Matsumoto K, Uemura N, Yanase K, Shirakami G, Ogino Y, Ueno M
Current issues in molecular biology 2023 Sep 26;45(10):7813-7826
Current issues in molecular biology 2023 Sep 26;45(10):7813-7826
SPI1-Mediated Upregulation of the CST1 Gene as an Independent Poor Prognostic Factor Accelerates Metastasis in Esophageal Squamous Cell Carcinoma (ESCC) by Interacting with MMP2.
Luo FF, Wang J, Zhang ZF, Lin ST, Huang TJ, Liu BQ, Fan ML, Peng LX, Zheng ST, Yang CF, Huang BJ
Frontiers in bioscience (Landmark edition) 2023 Sep 24;28(9):212
Frontiers in bioscience (Landmark edition) 2023 Sep 24;28(9):212
LncRNA CCAT1 facilitates the progression of gastric cancer via PTBP1-mediated glycolysis enhancement.
Zhang C, Wang H, Liu Q, Dai S, Tian G, Wei X, Li X, Zhao L, Shan B
Journal of experimental & clinical cancer research : CR 2023 Sep 23;42(1):246
Journal of experimental & clinical cancer research : CR 2023 Sep 23;42(1):246
DSCC1 interacts with HSP90AB1 and promotes the progression of lung adenocarcinoma via regulating ER stress.
Lin X, Liu YH, Zhang HQ, Wu LW, Li Q, Deng J, Zhang Q, Yang Y, Zhang C, Li YL, Hu J
Cancer cell international 2023 Sep 23;23(1):208
Cancer cell international 2023 Sep 23;23(1):208
Pan-cancer analysis and experimental validation identify ndc1 as a potential immunological, prognostic and therapeutic biomarker in pancreatic cancer.
Shen Q, Li J, Zhang C, Pan X, Li Y, Zhang X, En G, Pang B
Aging 2023 Sep 20;15(18):9779-9796
Aging 2023 Sep 20;15(18):9779-9796
USP25 promotes hepatocellular carcinoma progression by interacting with TRIM21 via the Wnt/β-catenin signaling pathway.
Liu Y, Ma J, Lu S, He P, Dong W
Chinese medical journal 2023 Sep 20;136(18):2229-2242
Chinese medical journal 2023 Sep 20;136(18):2229-2242
Progranulin promoted the proliferation, metastasis, and suppressed apoptosis via JAK2-STAT3/4 signaling pathway in papillary thyroid carcinoma.
Dong Y, Tan H, Wang L, Liu Z
Cancer cell international 2023 Sep 2;23(1):191
Cancer cell international 2023 Sep 2;23(1):191
Circular RNA METTL15/miR-374a-5p/ESCO2 axis induces colorectal cancer development.
Guo F, Luo Y, Ye G, Tang W
Acta biochimica Polonica 2023 Sep 16;70(3):541-549
Acta biochimica Polonica 2023 Sep 16;70(3):541-549
N-methylpiperazine-diepoxyovatodiolide ameliorates peritoneal fibrosis via suppressing TGF-β/Smad and JAK/STAT signaling pathway.
Mo M, Zeng Y, Zeng Y, Li S, He X, Chen X, Luo Q, Liu M, Luo C, Dou X, Peng F, Long H
Chemico-biological interactions 2023 Sep 1;382:110589
Chemico-biological interactions 2023 Sep 1;382:110589
Shikonin suppresses small cell lung cancer growth via inducing ATF3-mediated ferroptosis to promote ROS accumulation.
Qian X, Zhu L, Xu M, Liu H, Yu X, Shao Q, Qin J
Chemico-biological interactions 2023 Sep 1;382:110588
Chemico-biological interactions 2023 Sep 1;382:110588
CircUSP10 promotes liver cancer progression by regulating miR-211-5p/TCF12/EMT signaling pathway.
Chen X, Xu Y, Zhou Z, Zhao P, Zhou Z, Wang F, Zhong F, Du H
Heliyon 2023 Oct;9(10):e20649
Heliyon 2023 Oct;9(10):e20649
ANKRD22 knockdown suppresses papillary thyroid cell carcinoma growth and migration and modulates the Wnt/β-catenin signaling pathway.
Wu Y, Chen W, Zhang B, Liu H
Tissue & cell 2023 Oct;84:102193
Tissue & cell 2023 Oct;84:102193
Pingxiao capsule inhibits lung metastasis of triple-negative breast cancer and sensitizes breast cancer to radiotherapy.
Wenjuan T, Yu HU, Man Z, Mingzhi D, Tieming L, Ammar S, Yingzhuan Z, Yanmin Z
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2023 Oct;43(5):897-905
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2023 Oct;43(5):897-905
Degradation of HIF-1α induced by curcumol blocks glutaminolysis and inhibits epithelial-mesenchymal transition and invasion in colorectal cancer cells.
Bian Y, Yin G, Wang G, Liu T, Liang L, Yang X, Zhang W, Tang D
Cell biology and toxicology 2023 Oct;39(5):1957-1978
Cell biology and toxicology 2023 Oct;39(5):1957-1978
Pleckstrin homology and RhoGEF domain containing G4 (PLEKHG4) leads to the activation of RhoGTPases promoting the malignant phenotypes of thyroid cancer.
Yuan Q, Fan Y, Liu Z, Wang X, Jia M, Dong Y, Geng Z, Zheng J, Lu X
Apoptosis : an international journal on programmed cell death 2023 Oct;28(9-10):1315-1331
Apoptosis : an international journal on programmed cell death 2023 Oct;28(9-10):1315-1331
Regulation of the stem‑like properties of estrogen receptor‑positive breast cancer cells through NR2E3/NR2C2 signaling.
Xie S, Hu Y, Jin J, Fu L, Zhang C, Yang Q, Niu Y, Sheng Z
Experimental and therapeutic medicine 2023 Oct;26(4):474
Experimental and therapeutic medicine 2023 Oct;26(4):474
Nrf3 promotes the proliferation and migration of triple‑negative breast cancer by activating PI3K/AKT/mTOR and epithelial‑mesenchymal transition.
Chen WM, Hu QY, Hou W, Chen MW, Chen YH, Tang JC
Oncology letters 2023 Oct;26(4):443
Oncology letters 2023 Oct;26(4):443
ACLY promotes gastric tumorigenesis and accelerates peritoneal metastasis of gastric cancer regulated by HIF-1A.
Yan Z, Liu K, Xu P, Chen Z, Zhang P, Pei S, Cheng Q, Huang S, Li B, Lv J, Xu Z, Xu H, Yang L, Zhang D
Cell cycle (Georgetown, Tex.) 2023 Oct;22(20):2288-2301
Cell cycle (Georgetown, Tex.) 2023 Oct;22(20):2288-2301
IGF2BP2 promotes glycolysis and hepatocellular carcinoma stemness by stabilizing CDC45 mRNA via m6A modification.
Wu T, Liao L, Wu T, Chen S, Yi Q, Xu M
Cell cycle (Georgetown, Tex.) 2023 Oct;22(20):2245-2263
Cell cycle (Georgetown, Tex.) 2023 Oct;22(20):2245-2263
FN1 mediated activation of aspartate metabolism promotes the progression of triple-negative and luminal a breast cancer.
Chen C, Ye L, Yi J, Liu T, Li Z
Breast cancer research and treatment 2023 Oct;201(3):515-533
Breast cancer research and treatment 2023 Oct;201(3):515-533
Lemur tyrosine kinase 2 has a tumor-inhibition function in human glioblastoma by regulating the RUNX3/Notch pathway.
Zhang L, Luo P, Mao X, Sun J, Wei J, Yang Y, Zhang Y, Jiang X
Biochimica et biophysica acta. Molecular cell research 2023 Oct;1870(7):119509
Biochimica et biophysica acta. Molecular cell research 2023 Oct;1870(7):119509
UBE2V2 promotes metastasis by regulating EMT and predicts a poor prognosis in lung adenocarcinoma.
Yang Z, Wu G, Zhao J, Shi G, Zhou J, Zhou X
Cancer medicine 2023 Oct;12(19):19850-19865
Cancer medicine 2023 Oct;12(19):19850-19865
Role of Nucleobindin-2 in the Clinical Pathogenesis and Treatment Resistance of Glioblastoma.
Lin IC, Chang CH, Chong YB, Kuo SH, Cheng YW, Lieu AS, Tseng TT, Lin CJ, Tsai HP, Kwan AL
Cells 2023 Oct 9;12(19)
Cells 2023 Oct 9;12(19)
Xue-Jie-San prevents the early development of colitis-associated intestinal fibrosis by blocking Notch1 and FGL1 signaling pathways.
Gao Y, Lu LJ, Zhang ZZ, Yang X, Du J, Wen K, Huang H, Wang XP, Sun XL
Journal of ethnopharmacology 2023 Oct 28;315:116678
Journal of ethnopharmacology 2023 Oct 28;315:116678
Exosome-transported circHDAC1_004 Promotes Proliferation, Migration, and Angiogenesis of Hepatocellular Carcinoma by the miR-361-3p/NACC1 Axis.
Xu B, Jia W, Feng Y, Wang J, Wang J, Zhu D, Xu C, Liang L, Ding W, Zhou Y, Kong L
Journal of clinical and translational hepatology 2023 Oct 28;11(5):1079-1093
Journal of clinical and translational hepatology 2023 Oct 28;11(5):1079-1093
CYP19A1 promotes gastric cancer as part of a lipid metabolism-related gene signature related to the response of immunotherapy and prognosis.
Zhou X, Meng F, Xiao L, Shen H
BMC medical genomics 2023 Oct 2;16(1):228
BMC medical genomics 2023 Oct 2;16(1):228
Eriocitrin inhibits epithelial-mesenchymal transformation (EMT) in lung adenocarcinoma cells via triggering ferroptosis.
Gao M, Lai K, Deng Y, Lu Z, Song C, Wang W, Xu C, Li N, Geng Q
Aging 2023 Oct 2;15(19):10089-10104
Aging 2023 Oct 2;15(19):10089-10104
Dendrobium officinale polysaccharide Converts M2 into M1 Subtype Macrophage Polarization via the STAT6/PPAR-r and JAGGED1/NOTCH1 Signaling Pathways to Inhibit Gastric Cancer.
Zhao Y, Lu X, Huang H, Yao Y, Liu H, Sun Y
Molecules (Basel, Switzerland) 2023 Oct 12;28(20)
Molecules (Basel, Switzerland) 2023 Oct 12;28(20)
Exploring the anticancer potential of Actinidia chinensis Planch root extracts (acRoots) on hepatocellular carcinoma: A molecular mechanism study.
Qiu K, Xia Q, Chen H, Ye Q, Mao H, Tian M, Gan Y, Huang Q, Wang H, Duan S
Heliyon 2023 Nov;9(11):e21851
Heliyon 2023 Nov;9(11):e21851
The PI3K-AKT-mTOR signaling pathway mediates the cytoskeletal remodeling and epithelial-mesenchymal transition in bladder outlet obstruction.
Zhang Z, Zhanghuang C, Mi T, Jin L, Liu J, Li M, Wu X, Wang J, Li M, Wang Z, Guo P, He D
Heliyon 2023 Nov;9(11):e21281
Heliyon 2023 Nov;9(11):e21281
TRIM16 E121D variant affects the risk and prognosis of hepatocellular carcinoma by modulating the Wnt/β-catenin pathway.
Li S, Wang J, Chen H, Hou J, Shen T, Li J, Zhou B, Zhang B, Liu H, Jiang DK
Molecular carcinogenesis 2023 Nov;62(11):1686-1699
Molecular carcinogenesis 2023 Nov;62(11):1686-1699
Circ_0001589/miR-1248/HMGB1 axis enhances EMT-mediated metastasis and cisplatin resistance in cervical cancer.
Ma T, Guo J, Han J, Li L, Ren Y, Huang J, Diao G, Zheng X, Zheng Y
Molecular carcinogenesis 2023 Nov;62(11):1645-1658
Molecular carcinogenesis 2023 Nov;62(11):1645-1658
Macrophage microvesicle-derived circ_YTHDF2 in methamphetamine-induced chronic lung injury.
Chen L, Gu YJ, Zhang XG, Cheng L, Zhou MY, Yang Y, Wang Y
The Journal of physiology 2023 Nov;601(22):5107-5128
The Journal of physiology 2023 Nov;601(22):5107-5128
BMP4 Regulates EMT to be Involved in non-Syndromic Cleft lip With or Without Palate.
Hong JW, Yu Y, Wang LS, Li Z, Zhang R, Wang Q, Ding Z, Zhang JP, Zhang MR, Xu LC
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association 2023 Nov;60(11):1462-1473
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association 2023 Nov;60(11):1462-1473
RNA‑binding protein quaking 5 inhibits the progression of non‑small cell lung cancer by upregulating netrin‑4 expression.
Wu Z, Liu S, Pang G, Jiang H
Oncology reports 2023 Nov;50(5)
Oncology reports 2023 Nov;50(5)
RUNX1 promotes proliferation and migration in non-small cell lung cancer cell lines via the mTOR pathway.
Ma H, Jiang S, Yuan Y, Li J, Li Y, Lv Y, Du T, Guan J, Jiang X, Tian L, Zheng Q, Yang L, Li Q
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Nov;37(11):e23195
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Nov;37(11):e23195
Comprehensive analysis of P2Y family genes expression, immune characteristics, and prognosis in pan-cancer.
Liu C, Wang X, Wang S, Xiang J, Xie H, Tan Z, Li X, Zhang J, Dong W
Translational oncology 2023 Nov;37:101776
Translational oncology 2023 Nov;37:101776
PCSK9 promotes tumor cell proliferation and migration by facilitating CCL25 secretion in esophageal squamous cell carcinoma.
Wang H, Guo Q, Wang M, Liu C, Tian Z
Oncology letters 2023 Nov;26(5):500
Oncology letters 2023 Nov;26(5):500
B4GALNT1 promotes carcinogenesis by regulating epithelial-mesenchymal transition in hepatocellular carcinoma based on pan-cancer analysis.
Liu W, Chen Y, Yang J, Guo M, Wang L
The journal of gene medicine 2023 Nov;25(11):e3552
The journal of gene medicine 2023 Nov;25(11):e3552
Autophagy regulation and protein kinase activity of PIK3C3 controls sertoli cell polarity through its negative regulation on SCIN (scinderin).
Wang K, Kong F, Qiu Y, Chen T, Fu J, Jin X, Su Y, Gu Y, Hu Z, Li J
Autophagy 2023 Nov;19(11):2934-2957
Autophagy 2023 Nov;19(11):2934-2957
Hyperbranched polyamidoamine-RGD peptide/si-circICA1 in the treatment of invasive thyroid cancer through targeting of the miR-486-3p/SERPINA1 axis.
Dong S, Xia Q, Pan J, Du XL, Wu YJ, Xie XJ
Nanomedicine (London, England) 2023 Nov;18(27):2039-2059
Nanomedicine (London, England) 2023 Nov;18(27):2039-2059
CTRP6 regulates M1 macrophage polarization via the PPAR-γ/NF-κB pathway and reprogramming glycolysis in recurrent spontaneous abortion.
Yan S, Ding J, Wang Z, Zhang F, Li J, Zhang Y, Wu S, Yang L, Pang X, Zhang Y, Yang J
International immunopharmacology 2023 Nov;124(Pt A):110840
International immunopharmacology 2023 Nov;124(Pt A):110840
Icaritin inhibits endometrial carcinoma cells by suppressing O-GlcNAcylation of FOXC1.
Wang Y, Wang G, Liu Y, Yang F, Zhang H, Kong Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Nov;120:155062
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Nov;120:155062
A novel c-Met/TRK inhibitor 1D228 efficiently inhibits tumor growth by targeting angiogenesis and tumor cell proliferation.
An B, Nie W, Hu J, Fan Y, Nie H, Wang M, Zhao Y, Yao H, Ren Y, Zhang C, Wei M, Li W, Liu J, Yang C, Zhang Y, Li X, Tian G
Cell death & disease 2023 Nov 9;14(11):728
Cell death & disease 2023 Nov 9;14(11):728
Platycodin D inhibits glioblastoma cell proliferation, migration, and invasion by regulating DEPDC1B-mediated epithelial-to-mesenchymal transition.
Ouyang J, Li H, Wu G, Hei B, Liu R
European journal of pharmacology 2023 Nov 5;958:176074
European journal of pharmacology 2023 Nov 5;958:176074
Discovery of a novel dual-target inhibitor of CDK12 and PARP1 that induces synthetic lethality for treatment of triple-negative breast cancer.
Zhang L, Zhen Y, Feng L, Li Z, Lu Y, Wang G, Ouyang L
European journal of medicinal chemistry 2023 Nov 5;259:115648
European journal of medicinal chemistry 2023 Nov 5;259:115648
Ag/TiO(2) nanohybrids induce fibrosis-related epithelial-mesenchymal transition in lung epithelial cells and the influences of silver content and silver particle size.
Huang X, Li C, Wei T, Liu N, Zou L, Bai C, Yao Y, Wang Z, Xue Y, Wu T, Zhang T, Tang M
The Science of the total environment 2023 Nov 25;901:165875
The Science of the total environment 2023 Nov 25;901:165875
Synergistic anti-tumour activity of ginsenoside Rg3 and doxorubicin on proliferation, metastasis and angiogenesis in osteosarcoma by modulating mTOR/HIF-1α/VEGF and EMT signalling pathways.
Zeng X, Liu S, Yang H, Jia M, Liu W, Zhu W
The Journal of pharmacy and pharmacology 2023 Nov 23;75(11):1405-1417
The Journal of pharmacy and pharmacology 2023 Nov 23;75(11):1405-1417
STIM2 regulates NMDA receptor endocytosis that is induced by short-term NMDA receptor overactivation in cortical neurons.
Serwach K, Nurowska E, Klukowska M, Zablocka B, Gruszczynska-Biegala J
Cellular and molecular life sciences : CMLS 2023 Nov 21;80(12):368
Cellular and molecular life sciences : CMLS 2023 Nov 21;80(12):368
LMP2 and TAP2 impair tumor growth and metastasis by inhibiting Wnt/β-catenin signaling pathway and EMT in cervical cancer.
Cheng Z, Wang H, Yang Z, Li J, Chen X
BMC cancer 2023 Nov 20;23(1):1128
BMC cancer 2023 Nov 20;23(1):1128
FAM171B stabilizes vimentin and enhances CCL2-mediated TAM infiltration to promote bladder cancer progression.
Hu WM, Li M, Ning JZ, Tang YQ, Song TB, Li LZ, Zou F, Cheng F, Yu WM
Journal of experimental & clinical cancer research : CR 2023 Nov 2;42(1):290
Journal of experimental & clinical cancer research : CR 2023 Nov 2;42(1):290
Curcumin Disrupts a Positive Feedback Loop between ADMSCs and Cancer Cells in the Breast Tumor Microenvironment via the CXCL12/CXCR4 Axis.
Jang BY, Shin MK, Han DH, Sung JS
Pharmaceutics 2023 Nov 15;15(11)
Pharmaceutics 2023 Nov 15;15(11)
IGFBP2 drives epithelial-mesenchymal transition in hepatocellular carcinoma via activating the Wnt/β-catenin pathway.
Chen X, Zhang Y, Zhang P, Wei M, Tian T, Guan Y, Han C, Wei W, Ma Y
Infectious agents and cancer 2023 Nov 13;18(1):73
Infectious agents and cancer 2023 Nov 13;18(1):73
GAD1-mediated GABA elicits aggressive characteristics of human oral cancer cells.
Dou Z, Li M, Shen Z, Jiang H, Pang X, Li T, Liang X, Tang Y
Biochemical and biophysical research communications 2023 Nov 12;681:80-89
Biochemical and biophysical research communications 2023 Nov 12;681:80-89
Lnc AC016727.1/BACH1/HIF-1 α signal loop promotes the progression of non-small cell lung cancer.
Zhang L, Liang J, Qin H, Lv Y, Liu X, Li Z, Chao Z, Jia C, Qin X, Zhang H
Journal of experimental & clinical cancer research : CR 2023 Nov 10;42(1):296
Journal of experimental & clinical cancer research : CR 2023 Nov 10;42(1):296
The HDAC inhibitor HFY-4A improves TUSC2 transcription to induce immunogenic cell death in breast cancer.
Yin Y, Guan X, Li G, Chen C, Duan Y, Yu Z
Toxicology and applied pharmacology 2023 Nov 1;478:116698
Toxicology and applied pharmacology 2023 Nov 1;478:116698
Piezoeletric cold atmospheric plasma induces apoptosis and autophagy in human hepatocellular carcinoma cells through blocking glycolysis and AKT/mTOR/HIF-1α pathway.
Wang Y, Mang X, Li D, Chen Y, Cai Z, Tan F
Free radical biology & medicine 2023 Nov 1;208:134-152
Free radical biology & medicine 2023 Nov 1;208:134-152
Suprabasin enhances the invasion, migration, and angiogenic ability of oral squamous cell carcinoma cells under hypoxic conditions.
Houri A, Mukudai Y, Abe Y, Watanabe M, Nara M, Miyamoto S, Kurihara M, Shimane T, Shirota T
Oncology reports 2023 May;49(5)
Oncology reports 2023 May;49(5)
Naringenin in Si-Ni-San formula inhibits chronic psychological stress-induced breast cancer growth and metastasis by modulating estrogen metabolism through FXR/EST pathway.
Zhang J, Wang N, Zheng Y, Yang B, Wang S, Wang X, Pan B, Wang Z
Journal of advanced research 2023 May;47:189-207
Journal of advanced research 2023 May;47:189-207
MAP4K4 promotes ovarian cancer metastasis through diminishing ADAM10-dependent N-cadherin cleavage.
Chen K, Yuan X, Wang S, Zheng F, Fu Z, Shen Z, Cheng X, Wang Y, Tang S, Ni H, Wang F, Lu G, Wu Y, Xia D, Lu W
Oncogene 2023 May;42(18):1438-1452
Oncogene 2023 May;42(18):1438-1452
ADAM12 promotes gemcitabine resistance by activating EGFR signaling pathway and induces EMT in bladder cancer.
Wang R, Gao D, Chen C, Fan G, Cheng H, Tao Y, Lu J, Tian J, Wang Y, Wang Z
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2023 May;25(5):1425-1435
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2023 May;25(5):1425-1435
Deciphering the Clinical Significance and Kinase Functions of GSK3α in Colon Cancer by Proteomics and Phosphoproteomics.
Gao L, Lu Y, Chen HN, Li Z, Hu M, Zhang R, Wang X, Xu Z, Gong Y, Wang R, Du D, Hai S, Li S, Su D, Li Y, Xu H, Zhou ZG, Dai L
Molecular & cellular proteomics : MCP 2023 May;22(5):100545
Molecular & cellular proteomics : MCP 2023 May;22(5):100545
Phenotypic Heterogeneity Analysis of APC-Mutant Colon Cancer by Proteomics and Phosphoproteomics Identifies RAI14 as a Key Prognostic Determinant in East Asians and Westerners.
Zhang R, Hu M, Chen HN, Wang X, Xia Z, Liu Y, Wang R, Xia X, Shu Y, Du D, Meng W, Qi S, Li Y, Xu H, Zhou ZG, Dai L
Molecular & cellular proteomics : MCP 2023 May;22(5):100532
Molecular & cellular proteomics : MCP 2023 May;22(5):100532
BZW1 as an oncogene is associated with patient prognosis and the immune microenvironment in glioma.
Zhao L, Song C, Li Y, Yuan F, Zhao Q, Dong H, Liu B
Genomics 2023 May;115(3):110602
Genomics 2023 May;115(3):110602
The NR_109/FUBP1/c-Myc axis regulates TAM polarization and remodels the tumor microenvironment to promote cancer development.
Zhang C, Wei S, Dai S, Li X, Wang H, Zhang H, Sun G, Shan B, Zhao L
Journal for immunotherapy of cancer 2023 May;11(5)
Journal for immunotherapy of cancer 2023 May;11(5)
MicroRNA-150-5p inhibits the proliferation and invasion of human larynx epidermiod cancer cells though regulating peptidyl-prolyl cis/trans isomerase.
Chen H, Cai X, Du B, Cai J, Luo Z
Brazilian journal of otorhinolaryngology 2023 May-Jun;89(3):383-392
Brazilian journal of otorhinolaryngology 2023 May-Jun;89(3):383-392
High Level of GMFG Correlated to Poor Clinical Outcome and Promoted Cell Migration and Invasion through EMT Pathway in Triple-Negative Breast Cancer.
Zhao Y, Wei X, Li J, Diao Y, Shan C, Li W, Zhang S, Wu F
Genes 2023 May 26;14(6)
Genes 2023 May 26;14(6)
NEK2 promotes esophageal squamous cell carcinoma cell proliferation, migration and invasion through the Wnt/β-catenin signaling pathway.
Guo D, Yao W, Du X, Dong J, Zhang X, Shen W, Zhu S
Discover oncology 2023 May 26;14(1):80
Discover oncology 2023 May 26;14(1):80
PRMT2 promotes RCC tumorigenesis and metastasis via enhancing WNT5A transcriptional expression.
Li Z, Chen C, Yong H, Jiang L, Wang P, Meng S, Chu S, Li Z, Guo Q, Zheng J, Bai J, Li H
Cell death & disease 2023 May 12;14(5):322
Cell death & disease 2023 May 12;14(5):322
Growth and Migration Blocking Effect of Nanaomycin K, a Compound Produced by Streptomyces sp., on Prostate Cancer Cell Lines In Vitro and In Vivo.
Hirata Y, Shigemura K, Moriwaki M, Iwatsuki M, Kan Y, Ooya T, Maeda K, Yang Y, Nakashima T, Matsuo H, Nakanishi J, Fujisawa M
Cancers 2023 May 10;15(10)
Cancers 2023 May 10;15(10)
Decreasing expression of Prohibitin-2 lowers the oncogenicity of renal cell carcinoma cells by suppressing eIF4E-mediated oncogene translation via MNK inhibition.
Yang J, Li G, Huang Y, Liu Y
Toxicology and applied pharmacology 2023 May 1;466:116458
Toxicology and applied pharmacology 2023 May 1;466:116458
KIFC3 regulates progression of hepatocellular carcinoma via EMT and the AKT/mTOR pathway.
Lu S, Liu Y, Tian S, He Y, Dong W
Experimental cell research 2023 May 1;426(1):113564
Experimental cell research 2023 May 1;426(1):113564
The role of ferroptosis mediated by Bmal1/Nrf2 in nicotine -induce injury of BTB integrity.
Zhang Z, Cheng J, Yang L, Li X, Hua R, Xu D, Jiang Z, Li Q
Free radical biology & medicine 2023 May 1;200:26-35
Free radical biology & medicine 2023 May 1;200:26-35
Thiol oxidative stress-dependent degradation of transglutaminase2 via protein S-glutathionylation sensitizes 5-fluorouracil therapy in 5-fluorouracil-resistant colorectal cancer cells.
Li X, Ma Y, Wu J, Ni M, Chen A, Zhou Y, Dai W, Chen Z, Jiang R, Ling Y, Yao Q, Chen W
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2023 Mar;67:100930
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2023 Mar;67:100930
miR‑151a‑5p promotes the proliferation and metastasis of colorectal carcinoma cells by targeting AGMAT.
Xie Y, Zhang Y, Liu X, Cao L, Han M, Wang C, Chen J, Zhang X
Oncology reports 2023 Mar;49(3)
Oncology reports 2023 Mar;49(3)
Circ_0056618 enhances PRRG4 expression by competitively binding to miR-411-5p to promote the malignant progression of colorectal cancer.
Zhang B, Cao W, Liu Y, Zhao Y, Liu C, Sun B
Molecular and cellular biochemistry 2023 Mar;478(3):503-516
Molecular and cellular biochemistry 2023 Mar;478(3):503-516
CircNDST1 promotes papillary thyroid cancer progression via its interaction with CSNK2A1 to activate the PI3K-Akt pathway and epithelial-mesenchymal transition.
Shu C, Wang S, Hu J, Xu M, Deng H, Maimaiti Y, Huang T
Journal of endocrinological investigation 2023 Mar;46(3):545-557
Journal of endocrinological investigation 2023 Mar;46(3):545-557
Silencing RPL8 inhibits the progression of hepatocellular carcinoma by down-regulating the mTORC1 signalling pathway.
Sun T, Zhu W, Ru Q, Zheng Y
Human cell 2023 Mar;36(2):725-737
Human cell 2023 Mar;36(2):725-737
STMN2 overexpression promotes cell proliferation and EMT in pancreatic cancer mediated by WNT/β-catenin signaling.
Shao M, Wang L, Zhang Q, Wang T, Wang S
Cancer gene therapy 2023 Mar;30(3):472-480
Cancer gene therapy 2023 Mar;30(3):472-480
Cyclin-dependent kinase subunit2 (CKS2) promotes malignant phenotypes and epithelial-mesenchymal transition-like process in glioma by activating TGFβ/SMAD signaling.
Feng F, Zhao Z, Cai X, Heng X, Ma X
Cancer medicine 2023 Mar;12(5):5889-5907
Cancer medicine 2023 Mar;12(5):5889-5907
1,25(OH)(2) D(3) induced vitamin D receptor signaling negatively regulates endoplasmic reticulum-associated degradation (ERAD) and androgen receptor signaling in human prostate cancer cells.
Erzurumlu Y, Aydogdu E, Dogan HK, Catakli D, Muhammed MT, Buyuksandic B
Cellular signalling 2023 Mar;103:110577
Cellular signalling 2023 Mar;103:110577
The Enzyme 15-Hydroxyprostaglandin Dehydrogenase Inhibits a Shift to the Mesenchymal Pattern of Trophoblasts and Decidual Stromal Cells Accompanied by Prostaglandin Transporter in Preeclampsia.
Pang H, Lei D, Chen T, Liu Y, Fan C
International journal of molecular sciences 2023 Mar 7;24(6)
International journal of molecular sciences 2023 Mar 7;24(6)
HSPA5 Promotes the Proliferation, Metastasis and Regulates Ferroptosis of Bladder Cancer.
Wang Q, Ke S, Liu Z, Shao H, He M, Guo J
International journal of molecular sciences 2023 Mar 7;24(6)
International journal of molecular sciences 2023 Mar 7;24(6)
CPT1A modulates PI3K/Akt/mTOR pathway to promote preeclampsia.
Chen M, Chao B, Xu J, Liu Z, Tao Y, He J, Wang J, Yang H, Luo X, Qi H
Placenta 2023 Mar 3;133:23-31
Placenta 2023 Mar 3;133:23-31
Demethylase FTO enhances the PI3K/Akt signaling to promote gastric cancer malignancy.
Zhu Y, Yang J, Li Y, Xu J, Fang Z
Medical oncology (Northwood, London, England) 2023 Mar 27;40(5):130
Medical oncology (Northwood, London, England) 2023 Mar 27;40(5):130
Fatostatin induces ferroptosis through inhibition of the AKT/mTORC1/GPX4 signaling pathway in glioblastoma.
Cai J, Ye Z, Hu Y, Ye L, Gao L, Wang Y, Sun Q, Tong S, Zhang S, Wu L, Yang J, Chen Q
Cell death & disease 2023 Mar 25;14(3):211
Cell death & disease 2023 Mar 25;14(3):211
NONHSAT021545/miR-330-3p/EREG: A Cooperative Axis in Breast Cancer Prognosis and Treatment.
Zhang Y, Guo C, Yang S, Elkharti M, Liu R, Sun MZ, Liu S
Journal of clinical medicine 2023 Mar 24;12(7)
Journal of clinical medicine 2023 Mar 24;12(7)
PRAME Promotes Cervical Cancer Proliferation and Migration via Wnt/β-Catenin Pathway Regulation.
Chen X, Jiang M, Zhou S, Chen H, Song G, Wu Y, Zhu X
Cancers 2023 Mar 16;15(6)
Cancers 2023 Mar 16;15(6)
F-box and leucine-rich repeat 6 promotes gastric cancer progression via the promotion of epithelial-mesenchymal transition.
Meng L, Hu YT, Xu AM
World journal of gastrointestinal oncology 2023 Mar 15;15(3):490-503
World journal of gastrointestinal oncology 2023 Mar 15;15(3):490-503
Downregulation of PSAT1 inhibits cell proliferation and migration in uterine corpus endometrial carcinoma.
Wang M, Yue S, Yang Z
Scientific reports 2023 Mar 11;13(1):4081
Scientific reports 2023 Mar 11;13(1):4081
TMEM2 induces epithelial-mesenchymal transition and promotes resistance to temozolomide in GBM cells.
Gao L, Tong S, Liu J, Cai J, Ye Z, Zhou L, Song P, Li Z, Lei P, Wei H, Hua Q, Tian D, Cai Q
Heliyon 2023 Jun;9(6):e16559
Heliyon 2023 Jun;9(6):e16559
Potent carotenoid astaxanthin expands the anti-cancer activity of cisplatin in human prostate cancer cells.
Erzurumlu Y, Catakli D, Dogan HK
Journal of natural medicines 2023 Jun;77(3):572-583
Journal of natural medicines 2023 Jun;77(3):572-583
PDK1 regulates the progression of esophageal squamous cell carcinoma through metabolic reprogramming.
Ma Y, Zhang X, Han X, Hao Z, Ji R, Li J, Guo W, Zhang Y, Guan F, Ma S
Molecular carcinogenesis 2023 Jun;62(6):866-881
Molecular carcinogenesis 2023 Jun;62(6):866-881
ZNF133 is a potent suppressor in breast carcinogenesis through dampening L1CAM, a driver for tumor progression.
Li L, Wang X, Hu K, Liu X, Qiu L, Bai C, Cui Y, Wang B, Wang Z, Wang H, Cheng R, Hua J, Hai L, Wang M, Liu M, Song Z, Xiao C, Li B
Oncogene 2023 Jun;42(27):2166-2182
Oncogene 2023 Jun;42(27):2166-2182
Meso-Hannokinol inhibits breast cancer bone metastasis via the ROS/JNK/ZEB1 axis.
Zhu Y, Yin WF, Yu P, Zhang C, Sun MH, Kong LY, Yang L
Phytotherapy research : PTR 2023 Jun;37(6):2262-2279
Phytotherapy research : PTR 2023 Jun;37(6):2262-2279
Loss of exosomal miR-200b-3p from hypoxia cancer-associated fibroblasts promotes tumorigenesis and reduces sensitivity to 5-Flourouracil in colorectal cancer via upregulation of ZEB1 and E2F3.
Gong W, Guo Y, Yuan H, Chai R, Wan Z, Zheng B, Hu X, Chen B, Gao S, Dai Q, Yu P, Tu S
Cancer gene therapy 2023 Jun;30(6):905-916
Cancer gene therapy 2023 Jun;30(6):905-916
SETDB1 induces lenalidomide resistance in multiple myeloma cells via epithelial‑mesenchymal transition and PI3K/AKT pathway activation.
Qian X, Yang Y, Deng Y, Liu Y, Zhou Y, Han F, Xu Y, Yuan H
Experimental and therapeutic medicine 2023 Jun;25(6):274
Experimental and therapeutic medicine 2023 Jun;25(6):274
HnRNPAB is an independent prognostic factor in non‑small cell lung cancer and is involved in cell proliferation and metastasis.
Wang Q, Gou X, Liu L, Zhang T, Yuan H, Zhao Y, Xie Y, Zhou J, Song K
Oncology letters 2023 Jun;25(6):215
Oncology letters 2023 Jun;25(6):215
Targeting HMGA1 contributes to immunotherapy in aggressive breast cancer while suppressing EMT.
Chang X, Liu J, Yang Q, Gao Y, Ding X, Zhao J, Li Y, Liu Z, Li Z, Wu Y, Zuo D
Biochemical pharmacology 2023 Jun;212:115582
Biochemical pharmacology 2023 Jun;212:115582
LINC01116 modulates EMT process via binding with AGO1 mRNA in oesophageal squamous cell carcinoma.
Fang X, Ren LH, Shrestha SM, Ji Q, Xu Z, Wang D, Ding Q, Liang X, Shi RH
Biochimica et biophysica acta. Molecular cell research 2023 Jun;1870(5):119447
Biochimica et biophysica acta. Molecular cell research 2023 Jun;1870(5):119447
Squalene epoxidase promotes hepatocellular carcinoma development by activating STRAP transcription and TGF-β/SMAD signalling.
Zhang Z, Wu W, Jiao H, Chen Y, Ji X, Cao J, Yin F, Yin W
British journal of pharmacology 2023 Jun;180(12):1562-1581
British journal of pharmacology 2023 Jun;180(12):1562-1581
NPTX2 Promotes Epithelial-Mesenchymal Transition in Cutaneous Squamous Cell Carcinoma through METTL3-Mediated N6-Methyladenosine Methylation of SNAIL.
Kang T, Zhang C, Lei H, Luo R, Liu M, Wang S, Zhang X, Duan Q, Xiao S, Zheng Y
The Journal of investigative dermatology 2023 Jun;143(6):977-988.e2
The Journal of investigative dermatology 2023 Jun;143(6):977-988.e2
TRIM55 inhibits colorectal cancer development via enhancing protein degradation of c-Myc.
Lin M, Fang Z, Lin X, Zhou W, Wang Y, Han S, Ye M, Zhu F
Cancer medicine 2023 Jun;12(12):13511-13521
Cancer medicine 2023 Jun;12(12):13511-13521
MED27 plays a tumor-promoting role in breast cancer progression by targeting KLF4.
Wang R, Yu W, Zhu T, Lin F, Hua C, Ru L, Guo P, Wan X, Xue G, Guo Z, Han S, Lv K, Zhang G, Ge H, Guo W, Xu L, Deng W
Cancer science 2023 Jun;114(6):2277-2292
Cancer science 2023 Jun;114(6):2277-2292
MTAP-ANRIL gene fusion promotes melanoma epithelial-mesenchymal transition-like process by activating the JNK and p38 signaling pathways.
Lin Z, Lei Y, Wen M, He Q, Tian D, Xie H
Scientific reports 2023 Jun 5;13(1):9073
Scientific reports 2023 Jun 5;13(1):9073
SIAH1/CTR9 axis promotes the epithelial-mesenchymal transition of hepatocellular carcinoma.
Liu Z, Luo P, Cao K, Hu Q, Hu B, Cui L, Wang X, Shi H, Zhang B, Wang R
Carcinogenesis 2023 Jun 24;44(4):304-316
Carcinogenesis 2023 Jun 24;44(4):304-316
FBXO28 promotes proliferation, invasion, and metastasis of pancreatic cancer cells through regulation of SMARCC2 ubiquitination.
Liu S, Liu P, Zhu C, Yang R, He Z, Li Y, Li Y, Fei X, Hou J, Wang X, Pan Y
Aging 2023 Jun 21;15(12):5381-5398
Aging 2023 Jun 21;15(12):5381-5398
ORP8 inhibits renal cell carcinoma progression by accelerating Stathmin1 degradation and microtubule polymerization.
Zhang L, Pan Q, Wu Y, Zhang P, Li S, Xu Y, Li D, Zheng M, Pei D, Wang Q
Experimental cell research 2023 Jun 1;427(1):113601
Experimental cell research 2023 Jun 1;427(1):113601
Arsenic interferes with spermatogenesis involving Rictor/mTORC2-mediated blood-testis barrier disruption in mice.
Li X, Wang W, Hou Y, Li G, Yi H, Cui S, Zhang J, He X, Zhao H, Yang Z, Qiu Y, Liu Z, Xie J
Ecotoxicology and environmental safety 2023 Jun 1;257:114914
Ecotoxicology and environmental safety 2023 Jun 1;257:114914
Network pharmacology, molecular docking and experimental verification help unravel chelerythrine's potential mechanism in the treatment of gastric cancer.
Kai K, Han-Bing J, Bing-Lin C, Shu-Jun Z
Heliyon 2023 Jul;9(7):e17393
Heliyon 2023 Jul;9(7):e17393
MRPL51 is a downstream target of FOXM1 in promoting the malignant behaviors of lung adenocarcinoma.
Zhang W, Yu L, Xu C, Tang T, Cao J, Chen L, Pang X, Ren W
Oncology letters 2023 Jul;26(1):298
Oncology letters 2023 Jul;26(1):298
Analysis and validation of the potential of the MYO1E gene in pancreatic adenocarcinoma based on a bioinformatics approach.
Liu S, Liu P, Fei X, Zhu C, Hou J, Wang X, Pan Y
Oncology letters 2023 Jul;26(1):285
Oncology letters 2023 Jul;26(1):285
TANGO1 interacts with NRTN to promote hepatocellular carcinoma progression by regulating the PI3K/AKT/mTOR signaling pathway.
Man J, Zhou W, Zuo S, Zhao X, Wang Q, Ma H, Li HY
Biochemical pharmacology 2023 Jul;213:115615
Biochemical pharmacology 2023 Jul;213:115615
Disordered gut microbiota promotes atrial fibrillation by aggravated conduction disturbance and unbalanced linoleic acid/SIRT1 signaling.
Fang C, Zuo K, Liu Z, Liu Y, Liu L, Wang Y, Yin X, Li J, Liu X, Chen M, Yang X
Biochemical pharmacology 2023 Jul;213:115599
Biochemical pharmacology 2023 Jul;213:115599
SIRT3-mediated autophagy contributes to ferroptosis-induced anticancer by inducing the formation of BECN1-SLC7A11 complex.
Huang P, Zhao H, Pan X, Li J, Pan W, Dai H, Wang J, Xia C, Liu F
Biochemical pharmacology 2023 Jul;213:115592
Biochemical pharmacology 2023 Jul;213:115592
Genome-wide CRISPR knockout screening identified G protein pathway suppressor 2 as a novel tumor suppressor for uveal melanoma metastasis.
Shi S, Chen H, Wang H, Wan J, Shi Y, Li J, Wang S, Shi J, Lv J, Wu T, Wang L, Sun F
Journal of cancer research and clinical oncology 2023 Jul;149(7):3349-3360
Journal of cancer research and clinical oncology 2023 Jul;149(7):3349-3360
The role of DYNLT3 in breast cancer proliferation, migration, and invasion via epithelial-to-mesenchymal transition.
Wang H, Chen X, Jin Y, Liu T, Song Y, Zhu X, Zhu X
Cancer medicine 2023 Jul;12(14):15289-15303
Cancer medicine 2023 Jul;12(14):15289-15303
Pan-cancer analysis of oncogenic role of insulin-like growth factor-binding proteins and validation in ovarian cancer.
Tan W, Zhang J, Deng Z, Dai F, Tang L, Hu W, Liu H
Cancer medicine 2023 Jul;12(13):14833-14850
Cancer medicine 2023 Jul;12(13):14833-14850
HERPUD1, a Member of the Endoplasmic Reticulum Protein Quality Control Mechanism, may be a Good Target for Suppressing Tumorigenesis in Breast Cancer Cells.
Erzurumlu Y, Doğanlar Y, Doğan HK, Çataklı D
Turkish journal of pharmaceutical sciences 2023 Jul 7;20(3):157-164
Turkish journal of pharmaceutical sciences 2023 Jul 7;20(3):157-164
The promoting effect and mechanism of Nrf2 on cell metastasis in cervical cancer.
Zhang M, Hong X, Ma N, Wei Z, Ci X, Zhang S
Journal of translational medicine 2023 Jul 4;21(1):433
Journal of translational medicine 2023 Jul 4;21(1):433
Schwann cells regulate tumor cells and cancer-associated fibroblasts in the pancreatic ductal adenocarcinoma microenvironment.
Xue M, Zhu Y, Jiang Y, Han L, Shi M, Su R, Wang L, Xiong C, Wang C, Wang T, Deng S, Wu D, Cao Y, Dong L, Bai F, Zhao S, Deng X, Peng C, Li H, Chen J, Shen B, Jiang L, Chen H
Nature communications 2023 Jul 31;14(1):4600
Nature communications 2023 Jul 31;14(1):4600
Luteolin inhibits subretinal fibrosis and epithelial-mesenchymal transition in laser-induced mouse model via suppression of Smad2/3 and YAP signaling.
Zhang C, Zhang Y, Hu X, Zhao Z, Chen Z, Wang X, Zhang Z, Jin H, Zhang J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jul 25;116:154865
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jul 25;116:154865
Lnc-LRRTM4 promotes proliferation, metastasis and EMT of colorectal cancer through activating LRRTM4 transcription.
Zhang J, Meng X, Zhou Y, Jiang Z, Chen H, Meng Z, Zhang Q, Chen W
Cancer cell international 2023 Jul 19;23(1):142
Cancer cell international 2023 Jul 19;23(1):142
Fibronectin promotes tumor angiogenesis and progression of non-small-cell lung cancer by elevating WISP3 expression via FAK/MAPK/ HIF-1α axis and activating wnt signaling pathway.
Zhou F, Sun J, Ye L, Jiang T, Li W, Su C, Ren S, Wu F, Zhou C, Gao G
Experimental hematology & oncology 2023 Jul 19;12(1):61
Experimental hematology & oncology 2023 Jul 19;12(1):61
NCOA7 Regulates Growth and Metastasis of Clear Cell Renal Cell Carcinoma via MAPK/ERK Signaling Pathway.
Guo J, Ke S, Chen Q, Zhou J, Guo J, Qiu T
International journal of molecular sciences 2023 Jul 18;24(14)
International journal of molecular sciences 2023 Jul 18;24(14)
PLAGL2 promotes bladder cancer progression via RACGAP1/RhoA GTPase/YAP1 signaling.
Chen H, Yang W, Li Y, Ji Z
Cell death & disease 2023 Jul 15;14(7):433
Cell death & disease 2023 Jul 15;14(7):433
Long noncoding RNA LINC01594 inhibits the CELF6-mediated splicing of oncogenic CD44 variants to promote colorectal cancer metastasis.
Liu B, Song A, Gui P, Wang J, Pan Y, Li C, Li S, Zhang Y, Jiang T, Xu Y, Pei D, Song J
Cell death & disease 2023 Jul 14;14(7):427
Cell death & disease 2023 Jul 14;14(7):427
AFP deletion leads to anti-tumorigenic but pro-metastatic roles in liver cancers with concomitant CTNNB1 mutations.
Xu Y, Zhang X, Zhang R, Sun Y, Liu J, Luo C, Yang J, Fang W, Guo Q, Wei L
Cancer letters 2023 Jul 10;566:216240
Cancer letters 2023 Jul 10;566:216240
Knockdown of ABCB7 inhibits esophageal cancer progression by inhibiting the TGF-β/Smad signaling.
Feng S, Jia J, Lv G, Wang Y
Archives of biochemistry and biophysics 2023 Jul 1;742:109620
Archives of biochemistry and biophysics 2023 Jul 1;742:109620
Biochemical and clinical effects of RPS20 expression in renal clear cell carcinoma.
Shen C, Chen Z, Zhang Y, Xu W, Peng R, Jiang J, Zuo W, Fan Y, Zheng B
Oncology reports 2023 Jan;49(1)
Oncology reports 2023 Jan;49(1)
Resveratrol reverses TGF-β1-mediated invasion and metastasis of breast cancer cells via the SIRT3/AMPK/autophagy signal axis.
Wang J, Huang P, Pan X, Xia C, Zhang H, Zhao H, Yuan Z, Liu J, Meng C, Liu F
Phytotherapy research : PTR 2023 Jan;37(1):211-230
Phytotherapy research : PTR 2023 Jan;37(1):211-230
Formin protein DIAPH1 positively regulates PD-L1 expression and predicts the therapeutic response to anti-PD-1/PD-L1 immunotherapy.
Mei J, Cai Y, Wang H, Xu R, Zhou J, Lu J, Yang X, Pan J, Liu C, Xu J, Zhu Y
Clinical immunology (Orlando, Fla.) 2023 Jan;246:109204
Clinical immunology (Orlando, Fla.) 2023 Jan;246:109204
Exosomal miR-543 derived from umbilical cord mesenchymal stem cells ameliorates endometrial fibrosis in intrauterine adhesion via downregulating N-cadherin.
Yuan D, Guo T, Qian H, Jin C, Ge H, Zhao Y, Zhu D, Lin M, Wang H, Yu H
Placenta 2023 Jan;131:75-81
Placenta 2023 Jan;131:75-81
Multiomics analyses and machine learning of nuclear receptor coactivator 6 reveal its essential role in hepatocellular carcinoma.
Fang Y, Xu Y, Liao W, Ji T, Yu L, Li L, Pan M, Yang D
Cancer science 2023 Jan;114(1):75-90
Cancer science 2023 Jan;114(1):75-90
Hypermethylation-Mediated lncRNA MAGI2-AS3 Downregulation Facilitates Malignant Progression of Laryngeal Squamous Cell Carcinoma via Interacting With SPT6.
Wang J, Yang C, Cao H, Yang J, Meng W, Yu M, Yu L, Wang B
Cell transplantation 2023 Jan-Dec;32:9636897231154574
Cell transplantation 2023 Jan-Dec;32:9636897231154574
Lactoferrin Restores the Deoxynivalenol-Impaired Spermatogenesis and Blood-Testis Barrier Integrity via Improving the Antioxidant Capacity and Modifying the Cell Adhesion and Inflammatory Response.
Li Z, Zhao Y, Zong Q, Hu P, Bao W, Liu HY, Cai D
Antioxidants (Basel, Switzerland) 2023 Jan 9;12(1)
Antioxidants (Basel, Switzerland) 2023 Jan 9;12(1)
5'-tRF-GlyGCC promotes breast cancer metastasis by increasing fat mass and obesity-associated protein demethylase activity.
Chen F, Song C, Meng F, Zhu Y, Chen X, Fang X, Ma D, Wang Y, Zhang C
International journal of biological macromolecules 2023 Jan 31;226:397-409
International journal of biological macromolecules 2023 Jan 31;226:397-409
Glycolysis-Related Gene Analyses Indicate That DEPDC1 Promotes the Malignant Progression of Oral Squamous Cell Carcinoma via the WNT/β-Catenin Signaling Pathway.
Huang G, Chen S, Washio J, Paka Lubamba G, Takahashi N, Li C
International journal of molecular sciences 2023 Jan 19;24(3)
International journal of molecular sciences 2023 Jan 19;24(3)
Hypoxia-induced ROS aggravate tumor progression through HIF-1α-SERPINE1 signaling in glioblastoma.
Zhang L, Cao Y, Guo X, Wang X, Han X, Kanwore K, Hong X, Zhou H, Gao D
Journal of Zhejiang University. Science. B 2023 Jan 15;24(1):32-49
Journal of Zhejiang University. Science. B 2023 Jan 15;24(1):32-49
Molecular mechanism of the miR-7/BCL2L1/P53 signaling axis regulating the progression of hepatocellular carcinoma.
Zhang N, Wang F, Zhu L, Chang R, Mok SRS, Peixoto RD, Tang W, Chen Z
Annals of translational medicine 2023 Jan 15;11(1):12
Annals of translational medicine 2023 Jan 15;11(1):12
FRMD3 inhibits the growth and metastasis of breast cancer through the ubiquitination-mediated degradation of vimentin and subsequent impairment of focal adhesion.
Shao W, Li J, Piao Q, Yao X, Li M, Wang S, Song Z, Sun Y, Zheng L, Wang G, Liu L, Yu C, Huang Y, Bao Y, Sun L
Cell death & disease 2023 Jan 11;14(1):13
Cell death & disease 2023 Jan 11;14(1):13
CMTM6 overexpression confers trastuzumab resistance in HER2-positive breast cancer.
Xing F, Gao H, Chen G, Sun L, Sun J, Qiao X, Xue J, Liu C
Molecular cancer 2023 Jan 10;22(1):6
Molecular cancer 2023 Jan 10;22(1):6
High expression of NLRP12 predicts poor prognosis in patients with intracranial glioma.
Cheng YW, Chen YY, Lin CJ, Chen YT, Lieu AS, Tsai HP, Kwan AL
Journal of the Chinese Medical Association : JCMA 2023 Jan 1;86(1):88-97
Journal of the Chinese Medical Association : JCMA 2023 Jan 1;86(1):88-97
Etomidate elicits anti-tumor capacity by disrupting the JAK2/STAT3 signaling pathway in hepatocellular carcinoma.
Xu J, Zhang L, Li N, Dai J, Zhang R, Yao F, Zhou S, Wu Z, Zhou H, Zhou L, Li Q, Wang X, Liu C
Cancer letters 2023 Jan 1;552:215970
Cancer letters 2023 Jan 1;552:215970
A2aR inhibits fibrosis and the EMT process in silicosis by regulating Wnt/β-catenin pathway.
Tian Y, Xia J, Yang G, Li C, Qi Y, Dai K, Wu C, Guo Y, Yao W, Hao C
Ecotoxicology and environmental safety 2023 Jan 1;249:114410
Ecotoxicology and environmental safety 2023 Jan 1;249:114410
MALAT1-miR-30c-5p-CTGF/ATG5 axis regulates silica-induced experimental silicosis by mediating EMT in alveolar epithelial cells.
Xia J, Tian Y, Shao Z, Li C, Ding M, Qi Y, Xu X, Dai K, Wu C, Yao W, Hao C
Ecotoxicology and environmental safety 2023 Jan 1;249:114392
Ecotoxicology and environmental safety 2023 Jan 1;249:114392
The TGF-β/Smad(2/3) signaling pathway is involved in Musashi2-induced invasion and metastasis of colorectal cancer.
Yu ZL, Liu J, Ning ZK, Tian HK, Wu X, Huang YF, Wu ZC, Zong Z, Zhou TC
Molecular carcinogenesis 2023 Feb;62(2):261-276
Molecular carcinogenesis 2023 Feb;62(2):261-276
Silencing CircEIF3I/miR-526b-5p Axis Epigenetically Targets HGF/c-Met Signal to Hinder the Malignant Growth, Metastasis and Angiogenesis of Hepatocellular Carcinoma.
Liu Y, Xiao X, Wang J, Wang Y, Yu Y
Biochemical genetics 2023 Feb;61(1):48-68
Biochemical genetics 2023 Feb;61(1):48-68
Novel long noncoding RNA LINC02820 augments TNF signaling pathway to remodel cytoskeleton and potentiate metastasis in esophageal squamous cell carcinoma.
Wang J, Huang TJ, Mei Y, Luo FF, Xie DH, Peng LX, Liu BQ, Fan ML, Zhang JB, Zheng ST, Qian CN, Huang BJ
Cancer gene therapy 2023 Feb;30(2):375-387
Cancer gene therapy 2023 Feb;30(2):375-387
LIM and Cysteine-Rich Domains 1 Promotes Transforming Growth Factor β1-Induced Epithelial-Mesenchymal Transition in Human Kidney 2 Cells.
Yu R, Wu Y, He P, Bai Y, Zhang Y, Bian X, Sun G, Zhang B
Laboratory investigation; a journal of technical methods and pathology 2023 Feb;103(2):100016
Laboratory investigation; a journal of technical methods and pathology 2023 Feb;103(2):100016
RRP15 deficiency induces ribosome stress to inhibit colorectal cancer proliferation and metastasis via LZTS2-mediated β-catenin suppression.
Dong Z, Li J, Dai W, Yu D, Zhao Y, Liu S, Li X, Zhang Z, Zhang R, Liang X, Kong Q, Jin S, Jiang H, Jiang W, Ding C
Cell death & disease 2023 Feb 7;14(2):89
Cell death & disease 2023 Feb 7;14(2):89
Secretome of hESC-Derived MSC-like Immune and Matrix Regulatory Cells Mitigate Pulmonary Fibrosis through Antioxidant and Anti-Inflammatory Effects.
Hu W, Yang J, Xue J, Ma J, Wu S, Wang J, Xu R, Wei J, Wang Y, Wang S, Liu X
Biomedicines 2023 Feb 5;11(2)
Biomedicines 2023 Feb 5;11(2)
Serum Response Factor-Regulated IDO1/Kyn-Ahr Pathway Promotes Tumorigenesis of Oral Squamous Cell Carcinoma.
Xu M, Zhu F, Yin Q, Yin H, Fang S, Luo G, Huang J, Huang W, Liu F, Zhong M, Deng X
Cancers 2023 Feb 19;15(4)
Cancers 2023 Feb 19;15(4)
The malignancy of chordomas is enhanced via a circTLK1/miR-16-5p/Smad3 positive feedback axis.
Lou J, Zhang H, Huang Q, Chen C, Wang W, Niu J, Xu J, Ren T, Huang Y, Tang X, Guo W
Cell death discovery 2023 Feb 15;9(1):64
Cell death discovery 2023 Feb 15;9(1):64
METTL3 depletion contributes to tumour progression and drug resistance via N6 methyladenosine-dependent mechanism in HR+HER2-breast cancer.
Ouyang D, Hong T, Fu M, Li Y, Zeng L, Chen Q, He H, Wen Y, Cheng Y, Zhou M, Zou Q, Yi W
Breast cancer research : BCR 2023 Feb 10;25(1):19
Breast cancer research : BCR 2023 Feb 10;25(1):19
CircPTK2/PABPC1/SETDB1 axis promotes EMT-mediated tumor metastasis and gemcitabine resistance in bladder cancer.
Meng X, Xiao W, Sun J, Li W, Yuan H, Yu T, Zhang X, Dong W
Cancer letters 2023 Feb 1;554:216023
Cancer letters 2023 Feb 1;554:216023
Exosomes derived from human umbilical cord mesenchymal stem cells loaded with RVG-Lamp2b and Netrin-1 promotes Schwann cell invasion and migration.
He J, Du Z, Zhang H, Wang B, Xia J
Tissue & cell 2023 Dec;85:102219
Tissue & cell 2023 Dec;85:102219
AKAP12 inhibits esophageal squamous carcinoma cell proliferation, migration, and cell cycle via the PI3K/AKT signaling pathway.
Li X, Dong H, Zheng Y, Ding S, Li Y, Li H, Huang H, Zhong C, Xie T, Xu Y
Molecular and cellular probes 2023 Dec;72:101939
Molecular and cellular probes 2023 Dec;72:101939
Loke zupa decoction attenuates bronchial EMT-mediated airway remodelling in chronic asthma through the PI3K-Akt/HIF-1α signaling pathway.
Liu J, Li L, Han X, Chen Y, Diao J
Pharmaceutical biology 2023 Dec;61(1):1332-1342
Pharmaceutical biology 2023 Dec;61(1):1332-1342
Mechanisms of dihydromyricetin against hepatocellular carcinoma elucidated by network pharmacology combined with experimental validation.
Zhang S, Shi YN, Gu J, He P, Ai QD, Zhou XD, Wang W, Qin L
Pharmaceutical biology 2023 Dec;61(1):1108-1119
Pharmaceutical biology 2023 Dec;61(1):1108-1119
Abnormal activation of the Wnt3a/β-catenin signaling pathway promotes the expression of T-box transcription factor 3(TBX3) and the epithelial-mesenchymal transition pathway to mediate the occurrence of adenomyosis.
Li M, Li T, Jin T, Chen Y, Cheng L, Liang Q, Yan S, Li T, Ran Q, Chen W
Molecular biology reports 2023 Dec;50(12):9935-9950
Molecular biology reports 2023 Dec;50(12):9935-9950
Transcriptome sequencing identifies prognostic genes involved in gastric adenocarcinoma.
Li M, Bai M, Wu Y, Yang S, Zheng L, Sun L, Yu C, Huang Y
Molecular and cellular biochemistry 2023 Dec;478(12):2891-2906
Molecular and cellular biochemistry 2023 Dec;478(12):2891-2906
Selumetinib overcomes gefitinib primary and acquired resistance by regulating MIG6/STAT3 in NSCLC.
Song X, Wang L, Tang W, Yuan L, Liu Q, Li J, Fan D
Archives of pharmacal research 2023 Dec;46(11-12):924-938
Archives of pharmacal research 2023 Dec;46(11-12):924-938
Brusatol enhances MEF2A expression to inhibit RCC progression through the Wnt signalling pathway in renal cell carcinoma.
Wang T, Zhou Y, Bao H, Liu B, Wang M, Wang L, Pan T
Journal of cellular and molecular medicine 2023 Dec;27(23):3897-3910
Journal of cellular and molecular medicine 2023 Dec;27(23):3897-3910
ACTN1 promotes HNSCC tumorigenesis and cisplatin resistance by enhancing MYH9-dependent degradation of GSK-3β and integrin β1-mediated phosphorylation of FAK.
Cui L, Lu Y, Zheng J, Guo B, Zhao X
Journal of experimental & clinical cancer research : CR 2023 Dec 7;42(1):335
Journal of experimental & clinical cancer research : CR 2023 Dec 7;42(1):335
RUNX1 knockdown induced apoptosis and impaired EMT in high-grade serous ovarian cancer cells.
Chen Y, He Z, Yang S, Chen C, Xiong W, He Y, Liu S
Journal of translational medicine 2023 Dec 6;21(1):886
Journal of translational medicine 2023 Dec 6;21(1):886
Sinapine thiocyanate exhibited anti-colorectal cancer effects by inhibiting KRT6A/S100A2 axis.
Yang Y, Zeng Z, Li L, Lei S, Wu Y, Chen T, Zhang J
Cancer biology & therapy 2023 Dec 31;24(1):2249170
Cancer biology & therapy 2023 Dec 31;24(1):2249170
VAMP8 suppresses the metastasis via DDX5/β-catenin signal pathway in osteosarcoma.
Yang S, Zhou P, Zhang L, Xie X, Zhang Y, Bo K, Xue J, Zhang W, Liao F, Xu P, Hu Y, Yan R, Liu D, Chang J, Zhou K
Cancer biology & therapy 2023 Dec 31;24(1):2230641
Cancer biology & therapy 2023 Dec 31;24(1):2230641
Inhibition of TGF-β1-induced epithelial-mesenchymal transition in gliomas by DMC-HA.
Shi L, Wang Z, Rong J, Fei X, Li X, He B, Gong W, Qian J
Aging 2023 Dec 27;15(24):15183-15195
Aging 2023 Dec 27;15(24):15183-15195
ALOX5 acts as a key role in regulating the immune microenvironment in intrahepatic cholangiocarcinoma, recruiting tumor-associated macrophages through PI3K pathway.
Chen J, Tang Y, Qin D, Yu X, Tong H, Tang C, Tang Z
Journal of translational medicine 2023 Dec 20;21(1):923
Journal of translational medicine 2023 Dec 20;21(1):923
GABA induced by sleep deprivation promotes the proliferation and migration of colon tumors through miR-223-3p endogenous pathway and exosome pathway.
Bao H, Peng Z, Cheng X, Jian C, Li X, Shi Y, Zhu W, Hu Y, Jiang M, Song J, Fang F, Chen J, Shu X
Journal of experimental & clinical cancer research : CR 2023 Dec 18;42(1):344
Journal of experimental & clinical cancer research : CR 2023 Dec 18;42(1):344
Therapeutic protein PAK restrains the progression of triple negative breast cancer through degrading SREBP-1 mRNA.
Hu P, Zhou P, Sun T, Liu D, Yin J, Liu L
Breast cancer research : BCR 2023 Dec 11;25(1):151
Breast cancer research : BCR 2023 Dec 11;25(1):151
Dissecting T-cell heterogeneity in esophageal squamous cell carcinoma reveals the potential role of LAIR2 in antitumor immunity.
Wang P, Zhuang W, Zheng Z, Zhang L, Zhang X, Chen Q
Clinical and experimental immunology 2023 Dec 11;214(1):36-49
Clinical and experimental immunology 2023 Dec 11;214(1):36-49
Squalene epoxidase promotes breast cancer progression by regulating CCNB1 protein stability.
Tuluhong D, Gao H, Li X, Wang L, Zhu Y, Xu C, Wang J, Li H, Li Q, Wang S
Experimental cell research 2023 Dec 1;433(1):113805
Experimental cell research 2023 Dec 1;433(1):113805
Ginsenoside Rg1 Alleviates Lipopolysaccharide-Induced Fibrosis of Endometrial Epithelial Cells in Dairy Cows by Inhibiting Reactive Oxygen Species-Activated NLRP3.
Song L, Wang L, Li X, Xiao L
Animals : an open access journal from MDPI 2023 Dec 1;13(23)
Animals : an open access journal from MDPI 2023 Dec 1;13(23)
TAGLN2 Promotes the Proliferation, Migration, Invasion, and EMT of Clear Cell Renal Cell Carcinoma Through the PI3K/Akt Signaling Pathway.
He Y, Zhang B, Han D, Du Y, Zhang X, Wang H, Yue Z, Shang P
Biochemical genetics 2023 Aug;61(4):1265-1281
Biochemical genetics 2023 Aug;61(4):1265-1281
KIF15 knockdown inhibits the development of endometrial cancer by suppressing epithelial-mesenchymal transition and stemness through Wnt/β-catenin signaling.
Huang J, Sun X, Diao G, Li R, Guo J, Han J
Environmental toxicology 2023 Aug;38(8):1824-1834
Environmental toxicology 2023 Aug;38(8):1824-1834
High SNRPA1 expression leads to poor prognosis in patients with lung adenocarcinoma.
Yang JJ, Yang YJ, Gu YL, Tong L, Liu YF, Zhang JG
The clinical respiratory journal 2023 Aug;17(8):719-732
The clinical respiratory journal 2023 Aug;17(8):719-732
Combined effects of vitamin D and neferine on the progression and metastasis of colorectal cancer.
Yang J, Zhang Q, Huang G, Cong J, Wang T, Zhai X, Zhang J, Qi G, Zhou L, Jin J
Journal of cancer research and clinical oncology 2023 Aug;149(9):6203-6210
Journal of cancer research and clinical oncology 2023 Aug;149(9):6203-6210
Long non-coding RNA ENST00000503625 is a potential prognostic biomarker and metastasis suppressor gene in prostate cancer.
Li Y, Fang Z, Ge S, Li J, Qu L, Shi X, Zhang W, Sun Y, Ren S, Wang L
Journal of cancer research and clinical oncology 2023 Aug;149(10):7305-7317
Journal of cancer research and clinical oncology 2023 Aug;149(10):7305-7317
Inhibition of IL-4/STAT6/IRF4 signaling reduces the epithelial-mesenchymal transition in eosinophilic chronic rhinosinusitis with nasal polyps.
Chen J, Chen S, Gong G, Yang F, Chen J, Wang Y
International immunopharmacology 2023 Aug;121:110554
International immunopharmacology 2023 Aug;121:110554
ZDHHC11B is decreased in lung adenocarcinoma and inhibits tumorigenesis via regulating epithelial-mesenchymal transition.
Dai H, Wu R, Zhang J, Dou R, Xu M, Wang J, Wang J, Su F, Zhang T
Cancer medicine 2023 Aug;12(16):17212-17222
Cancer medicine 2023 Aug;12(16):17212-17222
Hypoxic tumor-derived exosomal miR-21 induces cancer-associated fibroblast activation to promote head and neck squamous cell carcinoma metastasis.
Ye B, Duan Y, Zhou M, Wang Y, Lai Q, Yue K, Cao J, Wu Y, Wang X, Jing C
Cellular signalling 2023 Aug;108:110725
Cellular signalling 2023 Aug;108:110725
SMC1A facilitates gastric cancer cell proliferation, migration, and invasion via promoting SNAIL activated EMT.
Liu Y, Fang X, Wang Q, Xiao D, Zhou T, Kang K, Peng Z, Ren F, Zhou J
BMC gastroenterology 2023 Aug 4;23(1):268
BMC gastroenterology 2023 Aug 4;23(1):268
High Thioredoxin Domain-Containing Protein 11 Expression Is Associated with Tumour Progression in Glioma.
Chen YT, Chung CL, Cheng YW, Lin CJ, Tseng TT, Hsu SS, Tsai HP, Kwan AL
International journal of molecular sciences 2023 Aug 29;24(17)
International journal of molecular sciences 2023 Aug 29;24(17)
Acetyl-cinobufagin suppresses triple-negative breast cancer progression by inhibiting the STAT3 pathway.
Qi Y, Wu H, Zhu T, Liu Z, Liu C, Yan C, Wu Z, Xu Y, Bai Y, Yang L, Cheng D, Zhang X, Zhao H, Zhao C, Dai X
Aging 2023 Aug 28;15(16):8258-8274
Aging 2023 Aug 28;15(16):8258-8274
Orosomucoid 1 promotes colorectal cancer progression and liver metastasis by affecting PI3K/AKT pathway and inducing macrophage M2 polarization.
Yue L, Xu X, Dai S, Xu F, Zhao W, Gu J, Dai X, Qian X
Scientific reports 2023 Aug 28;13(1):14092
Scientific reports 2023 Aug 28;13(1):14092
Underlying Molecular Mechanism and Construction of a miRNA-Gene Network in Idiopathic Pulmonary Fibrosis by Bioinformatics.
Zheng S, Zhang Y, Hou Y, Li H, He J, Zhao H, Sun X, Liu Y
International journal of molecular sciences 2023 Aug 27;24(17)
International journal of molecular sciences 2023 Aug 27;24(17)
CXCL8 Promotes Endothelial-to-Mesenchymal Transition of Endothelial Cells and Protects Cells from Erastin-Induced Ferroptosis via CXCR2-Mediated Activation of the NF-κB Signaling Pathway.
Ji HZ, Chen L, Ren M, Li S, Liu TY, Chen HJ, Yu HH, Sun Y
Pharmaceuticals (Basel, Switzerland) 2023 Aug 25;16(9)
Pharmaceuticals (Basel, Switzerland) 2023 Aug 25;16(9)
PHF23 promotes NSCLC proliferation, metastasis, and chemoresistance via stabilization of ACTN4 and activation of the ERK pathway.
Cheng M, Cao H, Yao P, Guan J, Wu P, Ji H, Jiang S, Yuan Y, Fu L, Zheng Q, Li Q
Cell death & disease 2023 Aug 25;14(8):558
Cell death & disease 2023 Aug 25;14(8):558
PNU-74654 Induces Cell Cycle Arrest and Inhibits EMT Progression in Pancreatic Cancer.
Chien TL, Wu YC, Lee HL, Sung WW, Yu CY, Chang YC, Lin CC, Wang CC, Tsai MC
Medicina (Kaunas, Lithuania) 2023 Aug 24;59(9)
Medicina (Kaunas, Lithuania) 2023 Aug 24;59(9)
Transforms of Cell Surface Glycoproteins Charge Influences Tumor Cell Metastasis via Atypically Inhibiting Epithelial-Mesenchymal Transition Including Matrix Metalloproteinases and Cell Junctions.
Wang M, Kejian S, Ye L, Chen J, Ma L
Bioconjugate chemistry 2023 Aug 16;34(8):1498-1507
Bioconjugate chemistry 2023 Aug 16;34(8):1498-1507
ADAMDEC1 induces EMT and promotes colorectal cancer cells metastasis by enhancing Wnt/β-catenin signaling via negative modulation of GSK-3β.
Jia Y, Huang X, Shi H, Wang M, Chen J, Zhang H, Hou D, Jing H, Du J, Han H, Zhang J
Experimental cell research 2023 Aug 15;429(2):113629
Experimental cell research 2023 Aug 15;429(2):113629
Claudin-3 facilitates the progression and mediates the tumorigenic effects of TGF-β in glioblastoma multiforme.
Sun Z, Yan T, Jiang H, Cai J, Zhu X, Chen Q
Medical oncology (Northwood, London, England) 2023 Aug 14;40(9):268
Medical oncology (Northwood, London, England) 2023 Aug 14;40(9):268
Ubiquitin-specific protease 7 prevents recurrent spontaneous abortion by targeting enhancer of zeste homolog 2 to regulate trophoblast proliferation, apoptosis, migration, and invasion through the Wnt/β-catenin pathway†.
Zhou M, Gao Y, Wu S, Chen J, Ding J, Wang Y, Yang J
Biology of reproduction 2023 Aug 10;109(2):204-214
Biology of reproduction 2023 Aug 10;109(2):204-214
Tumor cells-derived exosomal PD-L1 promotes the growth and invasion of lung cancer cells in vitro via mediating macrophages M2 polarization.
Lu X, Shen J, Huang S, Liu D, Wang H
European journal of histochemistry : EJH 2023 Aug 1;67(3)
European journal of histochemistry : EJH 2023 Aug 1;67(3)
Mitochondrial division inhibitor (mdivi-1) inhibits proliferation and epithelial-mesenchymal transition via the NF-κB pathway in thyroid cancer cells.
Zhang L, Sun L, Wang L, Wang J, Wang D, Jiang J, Zhang J, Zhou Q
Toxicology in vitro : an international journal published in association with BIBRA 2023 Apr;88:105552
Toxicology in vitro : an international journal published in association with BIBRA 2023 Apr;88:105552
Thrombospondin-1 mimic peptide PKHB1 induced endoplasmic reticulum stress-mediated but CD47-independent apoptosis in non-small cell lung cancer.
Ye J, Yao Y, Zhao J, Cui L, Lu G, Wang Q, Zhang P, Zhou J
Drug development research 2023 Apr;84(2):238-252
Drug development research 2023 Apr;84(2):238-252
Circular RNA Sec61 subunit alpha isoform 1 by competitive absorption of microRNA-513a-5p mediates peroxisomal biogenesis factor 5 expression and promotes the malignant phenotype of non-small cell lung cancer.
Duan ZP, Yu XJ, Wei HL
The Kaohsiung journal of medical sciences 2023 Apr;39(4):326-336
The Kaohsiung journal of medical sciences 2023 Apr;39(4):326-336
The aryl sulfonamide indisulam inhibits gastric cancer cell migration by promoting the ubiquitination and degradation of the transcription factor ZEB1.
Lu J, Li D, Jiang H, Li Y, Lu C, Chen T, Wang Y, Wang X, Sun W, Pu Z, Qiao C, Ma J, Xu G
The Journal of biological chemistry 2023 Apr;299(4):103025
The Journal of biological chemistry 2023 Apr;299(4):103025
ADAMTS12 promotes migration and epithelial-mesenchymal transition and predicts poor prognosis for pancreatic cancer.
He RZ, Zheng JH, Yao HF, Xu DP, Yang MW, Liu DJ, Sun YW, Huo YM
Hepatobiliary & pancreatic diseases international : HBPD INT 2023 Apr;22(2):169-178
Hepatobiliary & pancreatic diseases international : HBPD INT 2023 Apr;22(2):169-178
Budding uninhibited by benzimidazoles 1 overexpression is associated with poor prognosis and malignant phenotype: A promising therapeutic target for lung adenocarcinoma.
Chen R, Wang Z, Lu T, Liu Y, Ji Y, Yu Y, Tou F, Guo S
Thoracic cancer 2023 Apr;14(10):893-912
Thoracic cancer 2023 Apr;14(10):893-912
ETV4 Mediated Tumor-Associated Neutrophil Infiltration Facilitates Lymphangiogenesis and Lymphatic Metastasis of Bladder Cancer.
Zhang Q, Liu S, Wang H, Xiao K, Lu J, Chen S, Huang M, Xie R, Lin T, Chen X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Apr;10(11):e2205613
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Apr;10(11):e2205613
Radiation induces IRAK1 expression to promote radioresistance by suppressing autophagic cell death via decreasing the ubiquitination of PRDX1 in glioma cells.
Li J, Sun Y, Zhao X, Ma Y, Xie Y, Liu S, Hui B, Shi X, Sun X, Zhang X
Cell death & disease 2023 Apr 8;14(4):259
Cell death & disease 2023 Apr 8;14(4):259
ZSWIM1 Promotes the Proliferation and Metastasis of Lung Adenocarcinoma Cells through the STK38/MEKK2/ERK1/2 Axis.
Gao X, Lian Q, Guan B, Liu QY, Meng M, Chen Y, Jin J, Li H, Liu X, Sun Z, Liu L, He QY, Zhang G
Journal of proteome research 2023 Apr 7;22(4):1080-1091
Journal of proteome research 2023 Apr 7;22(4):1080-1091
Melatonin induces cell cycle arrest and suppresses tumor invasion in urinary bladder urothelial carcinoma.
Hsieh TY, Sung WW, Chang YC, Yu CY, Lu LY, Dong C, Lee TH, Chen SL
Aging 2023 Apr 21;15(8):3107-3119
Aging 2023 Apr 21;15(8):3107-3119
USP1 modulates hepatocellular carcinoma progression via the Hippo/TAZ axis.
Liu D, Li Q, Zang Y, Li X, Li Z, Zhang P, Feng C, Yang P, Cui J, Sun Y, Wei T, Su P, Zhao X, Yang H, Ding Y
Cell death & disease 2023 Apr 12;14(4):264
Cell death & disease 2023 Apr 12;14(4):264
LINC00365 functions as a tumor suppressor by inhibiting HIF-1α-mediated glucose metabolism reprogramming in breast cancer.
Liu B, Qu X, Wang J, Xu L, Zhang L, Xu B, Su J, Bian X
Experimental cell research 2023 Apr 1;425(1):113514
Experimental cell research 2023 Apr 1;425(1):113514
Aristolochic acid I promotes the invasion and migration of hepatocellular carcinoma cells by activating the C3a/C3aR complement system.
Li Y, Zhu S, Xue M, Jing Y, Liu X, Cai D, Zhao Y, Bian Y, Zhang Z, Zhang L
Toxicology letters 2023 Apr 1;378:51-60
Toxicology letters 2023 Apr 1;378:51-60
Classification of the mitochondrial ribosomal protein-associated molecular subtypes and identified a serological diagnostic biomarker in hepatocellular carcinoma.
Xie C, Hu J, Hu Q, Jiang L, Chen W
Frontiers in surgery 2022;9:1062659
Frontiers in surgery 2022;9:1062659
Non-canonical Small GTPase RBJ Promotes NSCLC Progression Through the Canonical MEK/ERK Signaling Pathway.
Wang Y, Shen X, Wang Q, Guo Z, Hu L, Dong Z, Hu W
Current pharmaceutical design 2022;28(42):3446-3455
Current pharmaceutical design 2022;28(42):3446-3455
Carbon Monoxide-Releasing Molecule-3 Suppresses the Malignant Biological Behavior of Tongue Squamous Cell Carcinoma via Regulating Keap1/Nrf2/HO-1 Signaling Pathway.
Dai Y, Chen H, Pan Y, Song H
BioMed research international 2022;2022:9418332
BioMed research international 2022;2022:9418332
PHGDH Inhibitor CBR-5884 Inhibits Epithelial Ovarian Cancer Progression via ROS/Wnt/β-Catenin Pathway and Plays a Synergistic Role with PARP Inhibitor Olaparib.
Zhang X, Sun M, Jiao Y, Lin B, Yang Q
Oxidative medicine and cellular longevity 2022;2022:9029544
Oxidative medicine and cellular longevity 2022;2022:9029544
Keratin 8 Is an Inflammation-Induced and Prognosis-Related Marker for Pancreatic Adenocarcinoma.
Xiong F, Guo T, Wang X, Wu G, Liu W, Wang Q, Wang B, Chen Y
Disease markers 2022;2022:8159537
Disease markers 2022;2022:8159537
JPHYD Inhibits miR-21-5p/Smad7-Mediated Epithelial-Mesenchymal Transition of Hepatocellular Carcinoma Cells.
Liu LH, Fang CK, Ge FC, Wang JN, Zhang XB, Luo R, Zhang Y, Feng KL, Qiu ZW, Zhong C
Journal of oncology 2022;2022:7823433
Journal of oncology 2022;2022:7823433
Xiaotan Sanjie Decoction Inhibits Gastric Cancer Cell Proliferation, Migration, and Invasion through lncRNA-ATB and miR-200A.
Zhou Z, Chen J, Li M, Cao L, Chen M, Zhang Q, Yu Z, Chai K
BioMed research international 2022;2022:7029182
BioMed research international 2022;2022:7029182
Comprehensive Pan-Cancer Analysis of IRAK Family Genes Identifies IRAK1 as a Novel Oncogene in Low-Grade Glioma.
Li J, Sun Y, Ma Y, Zhao X, Sun X, Wang Y, Zhang X
Journal of oncology 2022;2022:6497241
Journal of oncology 2022;2022:6497241
Multifunctional Drug-Loaded Phase-Change Nanoparticles Inhibit the Epithelial-Mesenchymal Transition of Hepatocellular Carcinoma by Affecting the Activity of Activated Hepatic Stellate Cells.
Zou X, Li T, Mao Y, Zhu M, Chen X, Niu J, Dong T, Jiang J, Yang X
BioMed research international 2022;2022:6441179
BioMed research international 2022;2022:6441179
TNFAIP6 Promotes Gastric Carcinoma Cell Invasion via Upregulating PTX3 and Activating the Wnt/β-Catenin Signaling Pathway.
Cui H, Zhang L, Chen B, Zhang F, Xu H, Ma G, Cao L, Wang M
Contrast media & molecular imaging 2022;2022:5697034
Contrast media & molecular imaging 2022;2022:5697034
ASPM Promotes the Progression of Anaplastic Thyroid Carcinomas by Regulating the Wnt/β-Catenin Signaling Pathway.
Jiang L, Zhang S, An N, Chai G, Ye C
International journal of endocrinology 2022;2022:5316102
International journal of endocrinology 2022;2022:5316102
CYP26A1 Is a Novel Cancer Biomarker of Pancreatic Carcinoma: Evidence from Integration Analysis and In Vitro Experiments.
Yu Y, Wang Y, Zou Y, Yu Y
Disease markers 2022;2022:5286820
Disease markers 2022;2022:5286820
DSC2 Suppresses the Metastasis of Gastric Cancer through Inhibiting the BRD4/Snail Signaling Pathway and the Transcriptional Activity of β-Catenin.
Sun C, Wang L, Du DD, Ji JB, Yang XX, Yu BF, Shang PF, Guo XL
Oxidative medicine and cellular longevity 2022;2022:4813571
Oxidative medicine and cellular longevity 2022;2022:4813571
Prognostic Lnc-S100B-2 Affects Cell Apoptosis and Microenvironment of Colorectal Cancer through MLLT10 Signaling.
Yi J, Peng F, Zhao J, Gong X
Journal of oncology 2022;2022:3565118
Journal of oncology 2022;2022:3565118
Biochanin A Suppresses Tumor Progression and PD-L1 Expression via Inhibiting ZEB1 Expression in Colorectal Cancer.
Xu J, Yang X, Pan J, Fan H, Mei J, Hua D
Journal of oncology 2022;2022:3224373
Journal of oncology 2022;2022:3224373
Upregulated LINC00922 Promotes Epithelial-Mesenchymal Transition and Indicates a Dismal Prognosis in Gastric Cancer.
Chen X, Hu L, Mao X, Chen H, She Y, Chi H, Zeng H, Guo L, Han Y
Journal of oncology 2022;2022:1608936
Journal of oncology 2022;2022:1608936
Novel lncRNA AL033381.2 Promotes Hepatocellular Carcinoma Progression by Upregulating PRKRA Expression.
Wang F, Zhu L, Xue Q, Tang C, Tang W, Zhang N, Dai C, Chen Z
Oxidative medicine and cellular longevity 2022;2022:1125932
Oxidative medicine and cellular longevity 2022;2022:1125932
ROS Promote Hypoxia-Induced Keratinocyte Epithelial-Mesenchymal Transition by Inducing SOX2 Expression and Subsequent Activation of Wnt/β-Catenin.
Shi Y, Wang S, Yang R, Wang Z, Zhang W, Liu H, Huang Y
Oxidative medicine and cellular longevity 2022;2022:1084006
Oxidative medicine and cellular longevity 2022;2022:1084006
Spheroid Formation Enhances the Regenerative Capacity of Nucleus Pulposus Cells via Regulating N-CDH and ITGβ1 Interaction.
Wang Y, Wang H, Zhuo Y, Hu Y, Li X, Xu Y, Sun B, Liu M, Zou L, Liu L, Luo L, Zhao C, Li P, Zhou Q
International journal of biological sciences 2022;18(9):3676-3696
International journal of biological sciences 2022;18(9):3676-3696
UBE2S as a novel ubiquitinated regulator of p16 and β-catenin to promote bone metastasis of prostate cancer.
Peng S, Chen X, Huang C, Yang C, Situ M, Zhou Q, Ling Y, Huang H, Huang M, Zhang Y, Cheng L, Zhang Q, Guo Z, Lai Y, Huang J
International journal of biological sciences 2022;18(8):3528-3543
International journal of biological sciences 2022;18(8):3528-3543
USP1 inhibition suppresses the progression of osteosarcoma via destabilizing TAZ.
Yuan P, Feng Z, Huang H, Wang G, Chen Z, Xu G, Xie Z, Jie Z, Zhao X, Ma Q, Wang S, Shen Y, Huang Y, Han Y, Ye H, Wang J, Shi P, Sun X
International journal of biological sciences 2022;18(8):3122-3136
International journal of biological sciences 2022;18(8):3122-3136
Minocycline binds and inhibits LYN activity to prevent STAT3-meditated metastasis of colorectal cancer.
Yang L, Yang J, Liu H, Lan J, Xu Y, Wu X, Mao Y, Wu D, Pan K, Zhang T
International journal of biological sciences 2022;18(6):2540-2552
International journal of biological sciences 2022;18(6):2540-2552
Decrease of circARID1A retards glioblastoma invasion by modulating miR-370-3p/ TGFBR2 pathway.
Li B, Chen J, Wu Y, Luo H, Ke Y
International journal of biological sciences 2022;18(13):5123-5135
International journal of biological sciences 2022;18(13):5123-5135
Interaction between BEND5 and RBPJ suppresses breast cancer growth and metastasis via inhibiting Notch signaling.
Shi Y, Zhang D, Chen J, Jiang Q, Song S, Mi Y, Wang T, Ye Q
International journal of biological sciences 2022;18(10):4233-4244
International journal of biological sciences 2022;18(10):4233-4244
Commensal microbe-derived SCFA alleviates atrial fibrillation via GPR43/NLRP3 signaling.
Zuo K, Fang C, Liu Z, Fu Y, Liu Y, Liu L, Wang Y, Yin X, Liu X, Li J, Zhong J, Chen M, Xu L, Yang X
International journal of biological sciences 2022;18(10):4219-4232
International journal of biological sciences 2022;18(10):4219-4232
Smurf2 suppresses the metastasis of hepatocellular carcinoma via ubiquitin degradation of Smad2.
Song D, Li S, Ning L, Zhang S, Cai Y
Open medicine (Warsaw, Poland) 2022;17(1):384-396
Open medicine (Warsaw, Poland) 2022;17(1):384-396
Clotrimazole Inhibits HCC Migration and Invasion by Modulating the ERK-p65 Signaling Pathway.
Liu X, Gao J, Sun Y, Zhang F, Guo W, Zhang S
Drug design, development and therapy 2022;16:863-871
Drug design, development and therapy 2022;16:863-871
TMEM158 Regulates the Canonical and Non-Canonical Pathways of TGF-β to Mediate EMT in Triple-Negative Breast Cancer.
Tong J, Li H, Hu Y, Zhao Z, Li M
Journal of Cancer 2022;13(8):2694-2704
Journal of Cancer 2022;13(8):2694-2704
Aberrant Expression of BUB1B Contributes to the Progression of Thyroid Carcinoma and Predicts Poor Outcomes for Patients.
Yan HC, Xiang C
Journal of Cancer 2022;13(7):2336-2351
Journal of Cancer 2022;13(7):2336-2351
Sinapine Thiocyanate Inhibits the Proliferation and Mobility of Pancreatic Cancer Cells by Up-Regulating GADD45A.
Wang J, Zeng Z, Lei S, Han J, Liao S, Zhang J, Wang L, Dong Y, Li H, Chen T
Journal of Cancer 2022;13(4):1229-1240
Journal of Cancer 2022;13(4):1229-1240
NRF2-directed PRPS1 upregulation to promote the progression and metastasis of melanoma.
Xiong G, Feng Y, Yi X, Zhang X, Li X, Yang L, Yi Z, Sai B, Yang Z, Zhang Q, Kuang Y, Zhu Y
Frontiers in immunology 2022;13:989263
Frontiers in immunology 2022;13:989263
Endoglin aggravates peritoneal fibrosis by regulating the activation of TGF-β/ALK/Smads signaling.
Huang Q, Xiao R, Lu J, Zhang Y, Xu L, Gao J, Sun J, Wang H
Frontiers in pharmacology 2022;13:973182
Frontiers in pharmacology 2022;13:973182
IL-22 regulates endometrial regeneration by enhancing tight junctions and orchestrating extracellular matrix.
Ganieva U, Schneiderman S, Bu P, Beaman K, Dambaeva S
Frontiers in immunology 2022;13:955576
Frontiers in immunology 2022;13:955576
A comprehensively prognostic and immunological analysis of actin-related protein 2/3 complex subunit 5 in pan-cancer and identification in hepatocellular carcinoma.
Huang S, Sun L, Hou P, Liu K, Wu J
Frontiers in immunology 2022;13:944898
Frontiers in immunology 2022;13:944898
Crosstalk of Histone and RNA Modifications Identified a Stromal-Activated Subtype with Poor Survival and Resistance to Immunotherapy in Gastric Cancer.
Yuan C, Zhang J, Deng C, Xia Y, Li B, Meng S, Jin X, Cheng L, Li H, Zhang C, He Y
Frontiers in pharmacology 2022;13:868830
Frontiers in pharmacology 2022;13:868830
KIFC3 Promotes Proliferation, Migration, and Invasion in Colorectal Cancer via PI3K/AKT/mTOR Signaling Pathway.
Liao H, Zhang L, Lu S, Li W, Dong W
Frontiers in genetics 2022;13:848926
Frontiers in genetics 2022;13:848926
Comprehensive analysis of a glycolysis and cholesterol synthesis-related genes signature for predicting prognosis and immune landscape in osteosarcoma.
Xu F, Yan J, Peng Z, Liu J, Li Z
Frontiers in immunology 2022;13:1096009
Frontiers in immunology 2022;13:1096009
Dysfunction of CCR1(+) decidual macrophages is a potential risk factor in the occurrence of unexplained recurrent pregnancy loss.
Sang Y, Li Y, Xu L, Chen J, Li D, Du M
Frontiers in immunology 2022;13:1045532
Frontiers in immunology 2022;13:1045532
COA3 overexpression promotes non-small cell lung cancer metastasis by reprogramming glucose metabolism.
Lin H, Gao Y, Sun K, Zhang Q, Li Y, Chen M, Jin F
American journal of cancer research 2022;12(8):3662-3678
American journal of cancer research 2022;12(8):3662-3678
The homeostatic malfunction of a novel feedback pathway formed by lncRNA021545, miR-330-3p and epiregulin contributes in hepatocarcinoma progression via mediating epithelial-mesenchymal transition.
Yang S, Zhang Y, Guo C, Liu R, Elkharti M, Ge Z, Liu Q, Liu S, Sun MZ
American journal of cancer research 2022;12(6):2492-2525
American journal of cancer research 2022;12(6):2492-2525
Decreased RNA m(6)A methylation enhances the process of the epithelial mesenchymal transition and vasculogenic mimicry in glioblastoma.
Tao M, Li X, He L, Rong X, Wang H, Pan J, Lu Z, Zhang X, Peng Y
American journal of cancer research 2022;12(2):893-906
American journal of cancer research 2022;12(2):893-906
Interleukin-17 promotes the development of ovarian cancer through upregulation of MTA1 expression.
Guo N, Zhang J
American journal of cancer research 2022;12(12):5646-5656
American journal of cancer research 2022;12(12):5646-5656
A novel epithelial-mesenchymal transition (EMT)-related gene signature of predictive value for the survival outcomes in lung adenocarcinoma.
Cui Y, Wang X, Zhang L, Liu W, Ning J, Gu R, Cui Y, Cai L, Xing Y
Frontiers in oncology 2022;12:974614
Frontiers in oncology 2022;12:974614
Novel LncRNA ZFHX4-AS1 as a Potential Prognostic Biomarker That Affects the Immune Microenvironment in Ovarian Cancer.
Wang X, Wang Y, Sun F, Xu Y, Zhang Z, Yang C, Zhang L, Lou G
Frontiers in oncology 2022;12:945518
Frontiers in oncology 2022;12:945518
Knockdown of USP8 inhibits prostate cancer cell growth, proliferation, and metastasis and promotes docetaxel's activity by suppressing the NF-kB signaling pathway.
Islam MT, Chen FZ, Chen HC, Wahid A
Frontiers in oncology 2022;12:923270
Frontiers in oncology 2022;12:923270
HPV16 E6-Activated OCT4 Promotes Cervical Cancer Progression by Suppressing p53 Expression via Co-Repressor NCOR1.
Shu S, Li Z, Liu L, Ying X, Zhang Y, Wang T, Zhou X, Jiang P, Lv W
Frontiers in oncology 2022;12:900856
Frontiers in oncology 2022;12:900856
OCT4 induces EMT and promotes ovarian cancer progression by regulating the PI3K/AKT/mTOR pathway.
Xie W, Yu J, Yin Y, Zhang X, Zheng X, Wang X
Frontiers in oncology 2022;12:876257
Frontiers in oncology 2022;12:876257
Chordin-Like 1 Regulates Epithelial-to-Mesenchymal Transition and Metastasis via the MAPK Signaling Pathway in Oral Squamous Cell Carcinoma.
Wu Q, Zheng Z, Zhang J, Piao Z, Xin M, Xiang X, Wu A, Zhao T, Huang S, Qiao Y, Zhou J, Xu S, Cheng H, Wu L, Ouyang K
Frontiers in oncology 2022;12:862751
Frontiers in oncology 2022;12:862751
Integrated Network Pharmacology and Experimental Verification to Explore the Molecular Mechanism of Hedysarum Multijugum Maxim-Curcumae Rhizoma Herb Pair for Treating Non-Small Cell Lung Cancer.
Hu S, Ge M, Zhang S, Jiang M, Hu K, Gao L
Frontiers in oncology 2022;12:854596
Frontiers in oncology 2022;12:854596
ACADL Functions as a Tumor Suppressor in Hepatocellular Carcinoma Metastasis by Inhibiting Matrix Metalloproteinase 14.
Guo D, Zhang X, Cui H, Yu D, Zhang H, Shi X, Pang C, Li J, Guo W, Zhang S
Frontiers in oncology 2022;12:821484
Frontiers in oncology 2022;12:821484
Analysis of L Antigen Family Member 3 as a Potential Biomarker and Therapeutic Target Associated With the Progression of Hepatocellular Carcinoma.
Chen Q, Lu X, Xie J, Ma N, Xu W, Zhang Z, Huang X, Liu H, Hou J, Zhang X, Zhu W
Frontiers in oncology 2022;12:813275
Frontiers in oncology 2022;12:813275
NUF2 Expression Promotes Lung Adenocarcinoma Progression and Is Associated With Poor Prognosis.
Jiang F, Huang X, Yang X, Zhou H, Wang Y
Frontiers in oncology 2022;12:795971
Frontiers in oncology 2022;12:795971
Syntenin Regulated by miR-216b Promotes Cancer Progression in Pancreatic Cancer.
Zu F, Chen H, Liu Q, Zang H, Li Z, Tan X
Frontiers in oncology 2022;12:790788
Frontiers in oncology 2022;12:790788
N-Glycosylation at Asn291 Stabilizes TIM-4 and Promotes the Metastasis of NSCLC.
Chen S, Wang Y, Liu W, Liang Y, Wang Y, Wu Z, Xu L, Liang X, Ma C, Gao L
Frontiers in oncology 2022;12:730530
Frontiers in oncology 2022;12:730530
GNG12 as A Novel Molecular Marker for the Diagnosis and Treatment of Glioma.
Liu R, Liu Z, Zhao Y, Cheng X, Liu B, Wang Y, Wang J, Lian X, Zhu Y, Gao Y
Frontiers in oncology 2022;12:726556
Frontiers in oncology 2022;12:726556
Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta gene as a tumour suppressor in stomach adenocarcinoma.
Li Y, Xiong JB, Jie ZG, Xiong H
Frontiers in oncology 2022;12:1069875
Frontiers in oncology 2022;12:1069875
Prognostic biomarker MCP-4 triggers epithelial-mesenchymal transition via the p38 MAPK pathway in ovarian cancer.
Li S, Hu Y, Liu O, Li X, Lin B
Frontiers in oncology 2022;12:1034737
Frontiers in oncology 2022;12:1034737
Consistent downregulation of the cleft lip/palate-associated genes IRF6 and GRHL3 in carcinomas.
Parisi L, Mockenhaupt C, Rihs S, Mansour F, Katsaros C, Degen M
Frontiers in oncology 2022;12:1023072
Frontiers in oncology 2022;12:1023072
Loss of CMTM6 promotes DNA damage-induced cellular senescence and antitumor immunity.
Wang H, Fan Y, Chen W, Lv Z, Wu S, Xuan Y, Wang C, Lu Y, Guo T, Shen D, Zhang F, Huang Q, Gao Y, Li H, Ma X, Wang B, Huang Y, Zhang X
Oncoimmunology 2022;11(1):2011673
Oncoimmunology 2022;11(1):2011673
Sophocarpine inhibits tumor progression by antagonizing the PI3K/AKT/mTOR signaling pathway in castration-resistant prostate cancer.
Weng M, Shi C, Han H, Zhu H, Xiao Y, Guo H, Yu Z, Wu C
PeerJ 2022;10:e14042
PeerJ 2022;10:e14042
CircFGGY Inhibits Cell Growth, Invasion and Epithelial-Mesenchymal Transition of Hepatocellular Carcinoma via Regulating the miR-545-3p/Smad7 Axis.
Feng KL, Diao N, Zhou ZW, Fang CK, Wang JN, Zhang Y, Luo R, Zhong C
Frontiers in cell and developmental biology 2022;10:850708
Frontiers in cell and developmental biology 2022;10:850708
Targeting MALT1 Suppresses the Malignant Progression of Colorectal Cancer via miR-375/miR-365a-3p/NF-κB Axis.
Qian R, Niu X, Wang Y, Guo Z, Deng X, Ding Z, Zhou M, Deng H
Frontiers in cell and developmental biology 2022;10:845048
Frontiers in cell and developmental biology 2022;10:845048
Maintenance of multipotency of bone marrow mesenchymal stem cells on poly(ε-caprolactone) nanoneedle arrays through the enhancement of cell-cell interaction.
Ren X, Gao X, Cheng Y, Xie L, Tong L, Li W, Chu PK, Wang H
Frontiers in bioengineering and biotechnology 2022;10:1076345
Frontiers in bioengineering and biotechnology 2022;10:1076345
Heat stress and hypoxia inhibit the secretion of androgens and induce epithelial-to-mesenchymal transition associated with activated TGF-β/Smad signalling in canine cryptorchidism.
Wang Z, Wang Q, Cui N, Xiao L, Wei H, Kang J, Sheng X, Qi X, Xing K, Guo Y, Ni H, Wang X
Reproduction in domestic animals = Zuchthygiene 2022 Sep;57(9):1046-1055
Reproduction in domestic animals = Zuchthygiene 2022 Sep;57(9):1046-1055
Irisin/FNDC5 inhibits the epithelial-mesenchymal transition of epithelial ovarian cancer cells via the PI3K/Akt pathway.
Zhu T, Zhang W, Zhang Y, Lu E, Liu H, Liu X, Yin S, Zhang P
Archives of gynecology and obstetrics 2022 Sep;306(3):841-850
Archives of gynecology and obstetrics 2022 Sep;306(3):841-850
GTSE1 promotes tumor growth and metastasis by attenuating of KLF4 expression in clear cell renal cell carcinoma.
Chen W, Wang H, Lu Y, Huang Y, Xuan Y, Li X, Guo T, Wang C, Lai D, Wu S, Zhao W, Mai H, Li H, Wang B, Ma X, Zhang X
Laboratory investigation; a journal of technical methods and pathology 2022 Sep;102(9):1011-1022
Laboratory investigation; a journal of technical methods and pathology 2022 Sep;102(9):1011-1022
TFAP2C Knockdown Sensitizes Bladder Cancer Cells to Cisplatin Treatment via Regulation of EGFR and NF-κB.
Xing J, Chen W, Chen K, Zhu S, Lin F, Qi Y, Zhang Y, Han S, Rao T, Ruan Y, Zhao S, Yu W, Cheng F
Cancers 2022 Sep 30;14(19)
Cancers 2022 Sep 30;14(19)
HOXA5 inhibits the proliferation of extrahepatic cholangiocarcinoma cells by enhancing MXD1 expression and activating the p53 pathway.
Xiong F, Liu W, Wang X, Wu G, Wang Q, Guo T, Huang W, Wang B, Chen Y
Cell death & disease 2022 Sep 27;13(9):829
Cell death & disease 2022 Sep 27;13(9):829
NR2F1 Regulates TGF-β1-Mediated Epithelial-Mesenchymal Transition Affecting Platinum Sensitivity and Immune Response in Ovarian Cancer.
Liang Q, Xu Z, Liu Y, Peng B, Cai Y, Liu W, Yan Y
Cancers 2022 Sep 24;14(19)
Cancers 2022 Sep 24;14(19)
Taraxasterol Inhibits Tumor Growth by Inducing Apoptosis and Modulating the Tumor Microenvironment in Non-Small Cell Lung Cancer.
Lu J, Shuai B, Shou Z, Guo W, Zhou C, Ouyang X, Zhou H, Li J, Cui J, Jiang F, Jin KY, Sarapultsev A, Li F, Zhang G, Luo S, Hu D
Cancers 2022 Sep 24;14(19)
Cancers 2022 Sep 24;14(19)
AHSA1 Promotes Proliferation and EMT by Regulating ERK/CALD1 Axis in Hepatocellular Carcinoma.
Zhang J, Ren Z, Zheng D, Song Z, Lin J, Luo Y, Zou X, Pan Y, Qi N, Li A, Liu X
Cancers 2022 Sep 22;14(19)
Cancers 2022 Sep 22;14(19)
Genistein Restricts the Epithelial Mesenchymal Transformation (EMT) and Stemness of Hepatocellular Carcinoma via Upregulating miR-1275 to Inhibit the EIF5A2/PI3K/Akt Pathway.
Yang X, Jiang W, Kong X, Zhou X, Zhu D, Kong L
Biology 2022 Sep 22;11(10)
Biology 2022 Sep 22;11(10)
Alcohol promotes epithelial mesenchymal transformation-mediated premetastatic niche formation of colorectal cancer by activating interaction between laminin-γ2 and integrin-β1.
Nong FF, Liang YQ, Xing SP, Xiao YF, Chen HH, Wen B
World journal of gastroenterology 2022 Sep 21;28(35):5154-5174
World journal of gastroenterology 2022 Sep 21;28(35):5154-5174
KCTD9 inhibits the Wnt/β-catenin pathway by decreasing the level of β-catenin in colorectal cancer.
Yao H, Ren D, Wang Y, Wu L, Wu Y, Wang W, Li Q, Liu L
Cell death & disease 2022 Sep 2;13(9):761
Cell death & disease 2022 Sep 2;13(9):761
Inhibition of PTPN21 has antitumor effects in glioma by restraining the EGFR/PI3K/AKT pathway.
Li XQ, Liu BC, Jiang XB, Gao WW, Rong B, Wei Y, Wang FL, Zhao HK, Zhang L
Toxicology and applied pharmacology 2022 Sep 15;451:116180
Toxicology and applied pharmacology 2022 Sep 15;451:116180
Label-free detection and enumeration of rare circulating tumor cells by bright-field image cytometry and multi-frame image correlation analysis.
Du Z, Li Y, Chen B, Wang L, Hu Y, Wang X, Zhang W, Yang X
Lab on a chip 2022 Sep 13;22(18):3390-3401
Lab on a chip 2022 Sep 13;22(18):3390-3401
Hypoxia-induced polarization of M2 macrophages and C-C motif chemokine ligand 5 secretion promotes the migration and invasion of trophoblasts†.
Chen X, Song QL, Ji R, Wang JY, Li ZH, Xiao ZN, Guo DY, Yang J
Biology of reproduction 2022 Sep 12;107(3):834-845
Biology of reproduction 2022 Sep 12;107(3):834-845
Amphiphilic Aminated Derivatives of [60]Fullerene as Potent Inhibitors of Tumor Growth and Metastasis.
Huo J, Li J, Liu Y, Yang L, Cao X, Zhao C, Lu Y, Zhou W, Li S, Liu J, Li J, Li X, Wan J, Wen R, Zhen M, Wang C, Bai C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Oct;9(29):e2201541
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Oct;9(29):e2201541
Exosomes derived from mesenchymal stem cells attenuate diabetic kidney disease by inhibiting cell apoptosis and epithelial-to-mesenchymal transition via miR-424-5p.
Cui C, Zang N, Song J, Guo X, He Q, Hu H, Yang M, Wang Y, Yang J, Zou Y, Gao J, Wang L, Wang C, Liu F, He F, Hou X, Chen L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Oct;36(10):e22517
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Oct;36(10):e22517
Identification of a five m6A-relevant mRNAs signature and risk score for the prognostication of gastric cancer.
Yin L, Feng S, Sun Y, Jiang Y, Tang C, Sun D
Journal of gastrointestinal oncology 2022 Oct;13(5):2234-2248
Journal of gastrointestinal oncology 2022 Oct;13(5):2234-2248
Transfer RNA-derived fragment 5'tRF-Gly promotes the development of hepatocellular carcinoma by direct targeting of carcinoembryonic antigen-related cell adhesion molecule 1.
Liu D, Wu C, Wang J, Zhang L, Sun Z, Chen S, Ding Y, Wang W
Cancer science 2022 Oct;113(10):3476-3488
Cancer science 2022 Oct;113(10):3476-3488
Natural shikonin and acetyl-shikonin improve intestinal microbial and protein composition to alleviate colitis-associated colorectal cancer.
Lin H, Ma X, Yang X, Chen Q, Wen Z, Yang M, Fu J, Yin T, Lu G, Qi J, Han H, Yang Y
International immunopharmacology 2022 Oct;111:109097
International immunopharmacology 2022 Oct;111:109097
Tension of plus-end tracking protein Clip170 confers directionality and aggressiveness during breast cancer migration.
Hu Y, Xie Q, Wu X, Liu W, Li D, Li C, Zhao W, Chen L, Zheng Z, Li G, Guo J
Cell death & disease 2022 Oct 8;13(10):856
Cell death & disease 2022 Oct 8;13(10):856
ALG3 Promotes Peritoneal Metastasis of Ovarian Cancer through Increasing Interaction of α1,3-mannosylated uPAR and ADAM8.
Cui X, Pei X, Wang H, Feng P, Qin H, Liu S, Yan Q, Liu J
Cells 2022 Oct 6;11(19)
Cells 2022 Oct 6;11(19)
IGF2BP2 Promotes Epithelial to Mesenchymal Transition and Metastasis through Stabilizing HMGA1 mRNA in Gastric Cancer.
Ouyang J, Li J, Li D, Jiang J, Hao T, Xia Y, Lu X, Zhang C, He Y
Cancers 2022 Oct 31;14(21)
Cancers 2022 Oct 31;14(21)
FTO Inhibits Epithelial Ovarian Cancer Progression by Destabilising SNAI1 mRNA through IGF2BP2.
Sun M, Zhang X, Bi F, Wang D, Zhou X, Li X, Yang Q
Cancers 2022 Oct 25;14(21)
Cancers 2022 Oct 25;14(21)
Downregulation of TUSC3 promotes EMT and hepatocellular carcinoma progression through LIPC/AKT axis.
Deng R, Lu X, Hong C, Cai R, Wang P, Xiong L, Wang X, Chen Q, Lin J
Journal of translational medicine 2022 Oct 23;20(1):485
Journal of translational medicine 2022 Oct 23;20(1):485
CAMK2N1 has a cancer-suppressive function in colorectal carcinoma via effects on the Wnt/β-catenin pathway.
Zhang X, Tian L, Li Z, Liu R, Yu J, Liu B
Biochemical and biophysical research communications 2022 Oct 20;626:220-228
Biochemical and biophysical research communications 2022 Oct 20;626:220-228
Radix Glycyrrhizae Preparata Induces Cell Cycle Arrest and Induced Caspase-Dependent Apoptosis in Glioblastoma Multiforme.
Lin TY, Wu TH, Tzou RD, Hsu YC, Lee KT, Tsai TH
Neurology international 2022 Oct 13;14(4):804-823
Neurology international 2022 Oct 13;14(4):804-823
Knockdown of TTC9 inhibits the proliferation, migration and invasion, but induces the apoptosis of lung adenocarcinoma cells.
Huang X, Jiang L, Wen Z, Yuan M, Zhong Y
Heliyon 2022 Nov;8(11):e11254
Heliyon 2022 Nov;8(11):e11254
Acyl-CoA thioesterase 9 promotes tumour growth and metastasis through reprogramming of fatty acid metabolism in hepatocellular carcinoma.
Wang B, Zhang H, Chen YF, Hu LQ, Tian YY, Tong HW, Wang G, Chen C, Yuan P
Liver international : official journal of the International Association for the Study of the Liver 2022 Nov;42(11):2548-2561
Liver international : official journal of the International Association for the Study of the Liver 2022 Nov;42(11):2548-2561
Targeting epiregulin in the treatment-damaged tumor microenvironment restrains therapeutic resistance.
Wang C, Long Q, Fu Q, Xu Q, Fu D, Li Y, Gao L, Guo J, Zhang X, Lam EW, Campisi J, Sun Y
Oncogene 2022 Nov;41(45):4941-4959
Oncogene 2022 Nov;41(45):4941-4959
Engineered biomimetic nanoreactor for synergistic photodynamic-chemotherapy against hypoxic tumor.
Guo H, Wang L, Wu W, Guo M, Yang L, Zhang Z, Cao L, Pu F, Huang X, Shao Z
Journal of controlled release : official journal of the Controlled Release Society 2022 Nov;351:151-163
Journal of controlled release : official journal of the Controlled Release Society 2022 Nov;351:151-163
Biomimetic cell membrane-coated glucose/oxygen-exhausting nanoreactor for remodeling tumor microenvironment in targeted hypoxic tumor therapy.
Guo H, Zhang W, Wang L, Shao Z, Huang X
Biomaterials 2022 Nov;290:121821
Biomaterials 2022 Nov;290:121821
Legumain affects the PI3K/AKT tumor progression pathway in retinoblastoma.
Tang Q, Xu F, Lin J, Zhang C, Liu X, Dong L, Zhao J, Zhu L, Lin T
Experimental eye research 2022 Nov;224:109221
Experimental eye research 2022 Nov;224:109221
MYPT1 inhibits the metastasis of renal clear cell carcinoma via the MAPK8/N-cadherin pathway.
Xie Q, Liu R, Zou Z, Feng Y, Huang Y, Xu G, Sun W, Liang Y, Zhong W
FEBS open bio 2022 Nov;12(11):2083-2095
FEBS open bio 2022 Nov;12(11):2083-2095
CHRNB2 represses pancreatic cancer migration and invasion via inhibiting β-catenin pathway.
Qin C, Li T, Wang Y, Zhao B, Li Z, Li T, Yang X, Zhao Y, Wang W
Cancer cell international 2022 Nov 7;22(1):340
Cancer cell international 2022 Nov 7;22(1):340
SIRT2 promotes the viability, invasion and metastasis of osteosarcoma cells by inhibiting the degradation of Snail.
Tian Y, Liu R, Hou X, Gao Z, Liu X, Zhang W
Cell death & disease 2022 Nov 7;13(11):935
Cell death & disease 2022 Nov 7;13(11):935
CBP-HSF2 structural and functional interplay in Rubinstein-Taybi neurodevelopmental disorder.
de Thonel A, Ahlskog JK, Daupin K, Dubreuil V, Berthelet J, Chaput C, Pires G, Leonetti C, Abane R, Barris LC, Leray I, Aalto AL, Naceri S, Cordonnier M, Benasolo C, Sanial M, Duchateau A, Vihervaara A, Puustinen MC, Miozzo F, Fergelot P, Lebigot É, Verloes A, Gressens P, Lacombe D, Gobbo J, Garrido C, Westerheide SD, David L, Petitjean M, Taboureau O, Rodrigues-Lima F, Passemard S, Sabéran-Djoneidi D, Nguyen L, Lancaster M, Sistonen L, Mezger V
Nature communications 2022 Nov 16;13(1):7002
Nature communications 2022 Nov 16;13(1):7002
MiR-30e-3p inhibits gastric cancer development by negatively regulating THO complex 2 and PI3K/AKT/mTOR signaling.
Gu XJ, Li YJ, Wang F, Ye T
World journal of gastrointestinal oncology 2022 Nov 15;14(11):2170-2182
World journal of gastrointestinal oncology 2022 Nov 15;14(11):2170-2182
Sertoli cells require TDP-43 to support spermatogenesis†.
Zomer HD, Osuru HP, Chebolu A, Rayl JM, Timken M, Reddi PP
Biology of reproduction 2022 Nov 14;107(5):1345-1359
Biology of reproduction 2022 Nov 14;107(5):1345-1359
NAP1L5 targeting combined with MYH9 Inhibit HCC progression through PI3K/AKT/mTOR signaling pathway.
Zhao R, Ge Y, Gong Y, Li B, Xiao B, Zuo S
Aging 2022 Nov 11;14(22):9000-9019
Aging 2022 Nov 11;14(22):9000-9019
KIF17 maintains the epithelial phenotype of breast cancer cells and curbs tumour metastasis.
Li T, Zhai D, Zhang M, Ye R, Kuang X, Shao N, Bi J, Lin Y
Cancer letters 2022 Nov 1;548:215904
Cancer letters 2022 Nov 1;548:215904
The inhibition of centromere protein K causes anticancer effects in breast carcinoma via effects on the FAK/PI3K/AKT/mTOR pathway.
Yu J, Wang K, Yang S, Li G
Toxicology and applied pharmacology 2022 Nov 1;454:116232
Toxicology and applied pharmacology 2022 Nov 1;454:116232
Kinesin family member 23, regulated by FOXM1, promotes triple negative breast cancer progression via activating Wnt/β-catenin pathway.
Li Z, Yang HY, Zhang XL, Zhang X, Huang YZ, Dai XY, Shi L, Zhou GR, Wei JF, Ding Q
Journal of experimental & clinical cancer research : CR 2022 May 7;41(1):168
Journal of experimental & clinical cancer research : CR 2022 May 7;41(1):168
Forkhead Box q1 promotes invasion and metastasis in colorectal cancer by activating the epidermal growth factor receptor pathway.
Zhang JJ, Cao CX, Wan LL, Zhang W, Liu ZJ, Wang JL, Guo Q, Tang H
World journal of gastroenterology 2022 May 7;28(17):1781-1797
World journal of gastroenterology 2022 May 7;28(17):1781-1797
FAM126A interacted with ENO1 mediates proliferation and metastasis in pancreatic cancer via PI3K/AKT signaling pathway.
Li Y, Li Y, Luo J, Fu X, Liu P, Liu S, Pan Y
Cell death discovery 2022 May 5;8(1):248
Cell death discovery 2022 May 5;8(1):248
FAT10 promotes chemotherapeutic resistance in pancreatic cancer by inducing epithelial-mesenchymal transition via stabilization of FOXM1 expression.
Zhu J, Zhao J, Luo C, Zhu Z, Peng X, Zhu X, Lin K, Bu F, Zhang W, Li Q, Wang K, Hu Z, Yu X, Chen L, Yuan R
Cell death & disease 2022 May 25;13(5):497
Cell death & disease 2022 May 25;13(5):497
[P4HA2 promotes occurrence and progression of liver cancer by regulating the PI3K/Akt/mTOR signaling pathway].
Shang L, Jiang W, Zhang J, Wu W
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2022 May 20;42(5):665-672
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2022 May 20;42(5):665-672
Arylquin 1 (Potent Par-4 Secretagogue) Inhibits Tumor Progression and Induces Apoptosis in Colon Cancer Cells.
Chen YT, Tseng TT, Tsai HP, Huang MY
International journal of molecular sciences 2022 May 18;23(10)
International journal of molecular sciences 2022 May 18;23(10)
TMCO1 expression promotes cell proliferation and induces epithelial-mesenchymal transformation in human gliomas.
Gao L, Ye Z, Liu JH, Yang JA, Li Y, Cai JY, Wang YX, Tong SA, Deng G, Zhang S, Chen QX
Medical oncology (Northwood, London, England) 2022 May 15;39(5):90
Medical oncology (Northwood, London, England) 2022 May 15;39(5):90
CXCL13 as a Novel Immune Checkpoint for Regulatory B Cells and Its Role in Tumor Metastasis.
Ren J, Lan T, Liu T, Liu Y, Shao B, Men K, Ma Y, Liang X, Wei YQ, Luo M, Wei XW
Journal of immunology (Baltimore, Md. : 1950) 2022 May 15;208(10):2425-2435
Journal of immunology (Baltimore, Md. : 1950) 2022 May 15;208(10):2425-2435
Stanniocalcin2 inhibits the epithelial-mesenchymal transition and invasion of trophoblasts via activation of autophagy under high-glucose conditions.
Lai R, Ji L, Zhang X, Xu Y, Zhong Y, Chen L, Hu H, Wang L
Molecular and cellular endocrinology 2022 May 1;547:111598
Molecular and cellular endocrinology 2022 May 1;547:111598
Downregulated RRS1 inhibits invasion and metastasis of BT549 through RPL11‑c‑Myc‑SNAIL axis.
Wang R, Peng C, Song J, Hua Y, Wu Q, Deng L, Cao Y, Zhang J, Zhang L, Wu L, Hou L
International journal of oncology 2022 Mar;60(3)
International journal of oncology 2022 Mar;60(3)
LACTB suppresses carcinogenesis in lung cancer and regulates the EMT pathway.
Xu Y, Shi H, Wang M, Huang P, Xu M, Han S, Li H, Wang Y
Experimental and therapeutic medicine 2022 Mar;23(3):247
Experimental and therapeutic medicine 2022 Mar;23(3):247
In situ injectable hydrogel-loaded drugs induce anti-tumor immune responses in melanoma immunochemotherapy.
Li J, Luo G, Zhang C, Long S, Guo L, Yang G, Wang F, Zhang L, Shi L, Fu Y, Zhang Y
Materials today. Bio 2022 Mar;14:100238
Materials today. Bio 2022 Mar;14:100238
LINC00244 suppresses cell growth and metastasis in hepatocellular carcinoma by downregulating programmed cell death ligand 1.
Sun Z, Xue C, Li J, Zhao H, Du Y, Du N
Bioengineered 2022 Mar;13(3):7635-7647
Bioengineered 2022 Mar;13(3):7635-7647
Inhibition of translocator protein 18 kDa suppressed the progression of glioma via the ELAV-like RNA-binding protein 1/MAPK-activated protein kinase 3 axis.
Wang J, Ren P, Zeng Z, Ma L, Li Y, Zhang H, Guo W
Bioengineered 2022 Mar;13(3):7457-7470
Bioengineered 2022 Mar;13(3):7457-7470
Transthyretin deposition alters cardiomyocyte sarcomeric architecture, calcium transients, and contractile force.
Dittloff KT, Spanghero E, Solís C, Banach K, Russell B
Physiological reports 2022 Mar;10(5):e15207
Physiological reports 2022 Mar;10(5):e15207
The cancer/testis antigen HORMAD1 mediates epithelial-mesenchymal transition to promote tumor growth and metastasis by activating the Wnt/β-catenin signaling pathway in lung cancer.
Liu K, Cheng L, Zhu K, Wang J, Shu Q
Cell death discovery 2022 Mar 28;8(1):136
Cell death discovery 2022 Mar 28;8(1):136
Ubiquitin conjugating enzyme E2 C (UBE2C) may play a dual role involved in the progression of thyroid carcinoma.
Xiang C, Yan HC
Cell death discovery 2022 Mar 24;8(1):130
Cell death discovery 2022 Mar 24;8(1):130
The miR-345-3p/PPP2CA signaling axis promotes proliferation and invasion of breast cancer cells.
Zeng Q, Jin F, Qian H, Chen H, Wang Y, Zhang D, Wei Y, Chen T, Guo B, Chai C
Carcinogenesis 2022 Mar 24;43(2):150-159
Carcinogenesis 2022 Mar 24;43(2):150-159
Engineering of thick human functional myocardium via static stretching and electrical stimulation.
Pretorius D, Kahn-Krell AM, LaBarge WC, Lou X, Zhang J
iScience 2022 Mar 18;25(3):103824
iScience 2022 Mar 18;25(3):103824
lncRNA SNHG26 promoted the growth, metastasis, and cisplatin resistance of tongue squamous cell carcinoma through PGK1/Akt/mTOR signal pathway.
Jiang Q, Wang Z, Qi Q, Li J, Xin Y, Qiu J
Molecular therapy oncolytics 2022 Mar 17;24:355-370
Molecular therapy oncolytics 2022 Mar 17;24:355-370
Restraint of chaperonin containing T-complex protein-1 subunit 3 has antitumor roles in non-small cell lung cancer via affection of YAP1.
Shi H, Zhang Y, Wang Y, Fang P, Liu Y, Li W
Toxicology and applied pharmacology 2022 Mar 15;439:115926
Toxicology and applied pharmacology 2022 Mar 15;439:115926
Pan-cancer analysis, cell and animal experiments revealing TEAD4 as a tumor promoter in ccRCC.
Li F, Feng Y, Jiang Q, Zhang J, Wu F, Li Q, Jing X, Wang X, Huang C
Life sciences 2022 Mar 15;293:120327
Life sciences 2022 Mar 15;293:120327
Deduction of CDC42EP3 suppress development and progression of osteosarcoma.
Xu P, Li X, Tang C, Wang T, Xu J
Experimental cell research 2022 Mar 1;412(1):113018
Experimental cell research 2022 Mar 1;412(1):113018
Identification of HMGCR as the anticancer target of physapubenolide against melanoma cells by in silico target prediction.
Wang HY, Yu P, Chen XS, Wei H, Cao SJ, Zhang M, Zhang Y, Tao YG, Cao DS, Qiu F, Cheng Y
Acta pharmacologica Sinica 2022 Jun;43(6):1594-1604
Acta pharmacologica Sinica 2022 Jun;43(6):1594-1604
Osthole inhibits the migration and invasion of highly metastatic breast cancer cells by suppressing ITGα3/ITGβ5 signaling.
Chen YQ, Song HY, Zhou ZY, Ma J, Luo ZY, Zhou Y, Wang JY, Liu S, Han XH
Acta pharmacologica Sinica 2022 Jun;43(6):1544-1555
Acta pharmacologica Sinica 2022 Jun;43(6):1544-1555
Circular RNA circ_0001459 accelerates hepatocellular carcinoma progression via the miR-6165/IGF1R axis.
Shen D, Zhao H, Zeng P, Ge M, Shrestha S, Zhao W
Annals of the New York Academy of Sciences 2022 Jun;1512(1):46-60
Annals of the New York Academy of Sciences 2022 Jun;1512(1):46-60
A neutrophil-mediated carrier regulates tumor stemness by inhibiting autophagy to prevent postoperative triple-negative breast cancer recurrence and metastasis.
Ren K, He J, Qiu Y, Xu Z, Wang X, Li J, Zang S, Yang Y, Li J, Long Y, Zhang Z, Li M, He Q
Acta biomaterialia 2022 Jun;145:185-199
Acta biomaterialia 2022 Jun;145:185-199
Circ_0005231 promotes the progression of esophageal squamous cell carcinoma via sponging miR-383-5p and regulating KIAA0101.
Sun Z, Zhang S, Zhang N, Wang J, Wang J, Liu J
Thoracic cancer 2022 Jun;13(12):1751-1762
Thoracic cancer 2022 Jun;13(12):1751-1762
CXCR4 inhibition attenuates calcium oxalate crystal deposition-induced renal fibrosis.
Ye Z, Xia Y, Zhou X, Li B, Yu W, Ruan Y, Li H, Ning J, Chen L, Rao T, Cheng F
International immunopharmacology 2022 Jun;107:108677
International immunopharmacology 2022 Jun;107:108677
Stress-induced epinephrine promotes epithelial-to-mesenchymal transition and stemness of CRC through the CEBPB/TRIM2/P53 axis.
Zhou Z, Shu Y, Bao H, Han S, Liu Z, Zhao N, Yuan W, Jian C, Shu X
Journal of translational medicine 2022 Jun 7;20(1):262
Journal of translational medicine 2022 Jun 7;20(1):262
Pharmacological Inhibition of Endogenous Hydrogen Sulfide Attenuates Breast Cancer Progression.
Khan NH, Wang D, Wang W, Shahid M, Khattak S, Ngowi EE, Sarfraz M, Ji XY, Zhang CY, Wu DD
Molecules (Basel, Switzerland) 2022 Jun 23;27(13)
Molecules (Basel, Switzerland) 2022 Jun 23;27(13)
Phenazine derivatives attenuate the stemness of breast cancer cells through triggering ferroptosis.
Yang Y, Lu Y, Zhang C, Guo Q, Zhang W, Wang T, Xia Z, Liu J, Cheng X, Xi T, Jiang F, Zheng L
Cellular and molecular life sciences : CMLS 2022 Jun 11;79(7):360
Cellular and molecular life sciences : CMLS 2022 Jun 11;79(7):360
The ETS1-LINC00278 negative feedback loop plays a role in COL4A1/COL4A2 regulation in laryngeal squamous cell carcinoma.
Yang C, Cao H, Yang JW, Wang JT, Yu MM, Wang BS
Neoplasma 2022 Jul;69(4):841-858
Neoplasma 2022 Jul;69(4):841-858
Methylation-mediated expression of SPARC is correlated with tumor progression and poor prognosis of breast cancer.
Li XL, Li JL, Qiu DJ, Ma L
Neoplasma 2022 Jul;69(4):794-806
Neoplasma 2022 Jul;69(4):794-806
Overexpression of ERCC6L correlates with poor prognosis and confers malignant phenotypes of lung adenocarcinoma.
Huang X, Jiang L, Lu S, Yuan M, Lin H, Li B, Wen Z, Zhong Y
Oncology reports 2022 Jul;48(1)
Oncology reports 2022 Jul;48(1)
Inhibition of PDK1 enhances radiosensitivity and reverses epithelial-mesenchymal transition in nasopharyngeal carcinoma.
Zhang W, Li L, Guo E, Zhou H, Ming J, Sun L, Hu G, Zhang L
Head & neck 2022 Jul;44(7):1576-1587
Head & neck 2022 Jul;44(7):1576-1587
Hypoxia-inducible factor-2α promotes EMT in esophageal squamous cell carcinoma through the Notch pathway.
Ji Z, Bao S, Li L, Wang D, Shi M, Liu X
Advances in clinical and experimental medicine : official organ Wroclaw Medical University 2022 Jul;31(7):795-805
Advances in clinical and experimental medicine : official organ Wroclaw Medical University 2022 Jul;31(7):795-805
Autophagy deficiency promotes lung metastasis of prostate cancer via stabilization of TWIST1.
Shi YX, Sun ZW, Jia DL, Wang HB
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2022 Jul;24(7):1403-1412
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2022 Jul;24(7):1403-1412
LncRNA HOTTIP PROMOTES OVARIAN CANCER CELL INVASION AND METASTASIS BY STABILIZING HIF-1α IN THE ANOXIC CELLULAR MICROENVIRONMENT.
Zhang S, Ma Q, Wu X, Chen P
Acta endocrinologica (Bucharest, Romania : 2005) 2022 Jul-Sep;18(3):263-270
Acta endocrinologica (Bucharest, Romania : 2005) 2022 Jul-Sep;18(3):263-270
Discovery of Novel Phosphoinositide-3-Kinase α Inhibitors with High Selectivity, Excellent Bioavailability, and Long-Acting Efficacy for Gastric Cancer.
Hou Y, Zhang F, Min W, Yuan K, Kuang W, Wang X, Zhu Y, Sun C, Xia F, Wang Y, Zhang H, Wang L, Yang P
Journal of medicinal chemistry 2022 Jul 28;65(14):9873-9892
Journal of medicinal chemistry 2022 Jul 28;65(14):9873-9892
Ginsenoside Rh4 Suppresses Metastasis of Esophageal Cancer and Expression of c-Myc via Targeting the Wnt/β-Catenin Signaling Pathway.
Chen J, Duan Z, Liu Y, Fu R, Zhu C
Nutrients 2022 Jul 25;14(15)
Nutrients 2022 Jul 25;14(15)
CircGPR137B/miR-4739/FTO feedback loop suppresses tumorigenesis and metastasis of hepatocellular carcinoma.
Liu L, Gu M, Ma J, Wang Y, Li M, Wang H, Yin X, Li X
Molecular cancer 2022 Jul 20;21(1):149
Molecular cancer 2022 Jul 20;21(1):149
Hyaluronic Acid Modified Nanostructured Lipid Carrier for Targeting Delivery of Kaempferol to NSCLC: Preparation, Optimization, Characterization, and Performance Evaluation In Vitro.
Ma Y, Liu J, Cui X, Hou J, Yu F, Wang J, Wang X, Chen C, Tong L
Molecules (Basel, Switzerland) 2022 Jul 17;27(14)
Molecules (Basel, Switzerland) 2022 Jul 17;27(14)
The Chinese medicine Fufang Zhenzhu Tiaozhi capsule protects against atherosclerosis by suppressing EndMT via modulating Akt1/β-catenin signaling pathway.
Diao H, Cheng J, Huang X, Huang B, Shao X, Zhao J, Lan D, Zhu Q, Yan M, Zhang Y, Rong X, Guo J
Journal of ethnopharmacology 2022 Jul 15;293:115261
Journal of ethnopharmacology 2022 Jul 15;293:115261
RBM47 inhibits hepatocellular carcinoma progression by targeting UPF1 as a DNA/RNA regulator.
Guo T, You K, Chen X, Sun Y, Wu Y, Wu P, Jiang Y
Cell death discovery 2022 Jul 14;8(1):320
Cell death discovery 2022 Jul 14;8(1):320
Deubiquitinase USP13 promotes the epithelial-mesenchymal transition and metastasis in gastric cancer by maintaining Snail protein.
Zhang T, Zheng J, Qiao L, Zhao W
Pathology, research and practice 2022 Jan;229:153705
Pathology, research and practice 2022 Jan;229:153705
MICAL1 inhibits colorectal cancer cell migration and proliferation by regulating the EGR1/β-catenin signaling pathway.
Gu H, Li Y, Cui X, Cao H, Hou Z, Ti Y, Liu D, Gao J, Wang Y, Wen P
Biochemical pharmacology 2022 Jan;195:114870
Biochemical pharmacology 2022 Jan;195:114870
Dihydroartemisinin represses oral squamous cell carcinoma progression through downregulating mitochondrial calcium uniporter.
Zheng S, Wu R, Deng Y, Zhang Q
Bioengineered 2022 Jan;13(1):227-241
Bioengineered 2022 Jan;13(1):227-241
circUSP34 accelerates osteosarcoma malignant progression by sponging miR-16-5p.
Lou J, Zhang H, Xu J, Ren T, Huang Y, Tang X, Guo W
Cancer science 2022 Jan;113(1):120-131
Cancer science 2022 Jan;113(1):120-131
YTHDF3 facilitates triple-negative breast cancer progression and metastasis by stabilizing ZEB1 mRNA in an m(6)A-dependent manner.
Lin Y, Jin X, Nie Q, Chen M, Guo W, Chen L, Li Y, Chen X, Zhang W, Chen H, Jiang M, Xiao H, Zhang J, Fu F, Wang C
Annals of translational medicine 2022 Jan;10(2):83
Annals of translational medicine 2022 Jan;10(2):83
G-protein Coupled Receptor 34 Promotes Gliomagenesis by Inducing Proliferation and Malignant Phenotype via TGF-Beta/Smad Signaling Pathway.
Cheng Y, Heng X, Feng F
Technology in cancer research & treatment 2022 Jan-Dec;21:15330338221105733
Technology in cancer research & treatment 2022 Jan-Dec;21:15330338221105733
miR-498 Targets UBE2T to Inhibit the Proliferation of Malignant Melanoma Cells.
Cao W, Ni L, Li P, Wang QX, Li MM, Huang SH, Dang NN
Technology in cancer research & treatment 2022 Jan-Dec;21:15330338221082431
Technology in cancer research & treatment 2022 Jan-Dec;21:15330338221082431
Astragalus membranaceus (Huangqi) and Rhizoma curcumae (Ezhu) decoction suppresses colorectal cancer via downregulation of Wnt5/β-Catenin signal.
Bian Y, Wang G, Zhou J, Yin G, Liu T, Liang L, Yang X, Zhang W, Ni K, Tang D, Yu Y
Chinese medicine 2022 Jan 6;17(1):11
Chinese medicine 2022 Jan 6;17(1):11
STK25 enhances hepatocellular carcinoma progression through the STRN/AMPK/ACC1 pathway.
Zhang Y, Xu J, Qiu Z, Guan Y, Zhang X, Zhang X, Chai D, Chen C, Hu Q, Wang W
Cancer cell international 2022 Jan 5;22(1):4
Cancer cell international 2022 Jan 5;22(1):4
Circ_0078607 inhibits the progression of ovarian cancer via regulating the miR-32-5p/SIK1 network.
Jin Y, Wang H
Journal of ovarian research 2022 Jan 4;15(1):3
Journal of ovarian research 2022 Jan 4;15(1):3
HERC3 regulates epithelial-mesenchymal transition by directly ubiquitination degradation EIF5A2 and inhibits metastasis of colorectal cancer.
Zhang Z, He G, Lv Y, Liu Y, Niu Z, Feng Q, Hu R, Xu J
Cell death & disease 2022 Jan 21;13(1):74
Cell death & disease 2022 Jan 21;13(1):74
Identification of Pyruvate Carboxylase as the Cellular Target of Natural Bibenzyls with Potent Anticancer Activity against Hepatocellular Carcinoma via Metabolic Reprogramming.
Sheng Y, Chen Y, Zeng Z, Wu W, Wang J, Ma Y, Lin Y, Zhang J, Huang Y, Li W, Zhu Q, Wei X, Li S, Wisanwattana W, Li F, Liu W, Suksamrarn A, Zhang G, Jiao W, Wang F
Journal of medicinal chemistry 2022 Jan 13;65(1):460-484
Journal of medicinal chemistry 2022 Jan 13;65(1):460-484
ZC3H15 promotes glioblastoma progression through regulating EGFR stability.
Hou J, Xu M, Gu H, Pei D, Liu Y, Huang P, Chang H, Cui H
Cell death & disease 2022 Jan 13;13(1):55
Cell death & disease 2022 Jan 13;13(1):55
CACNA1B facilitates breast cancer cell growth and migration by regulating cyclin D1 and EMT: the implication of CACNA1B in breast cancer.
Jin YM, Ye Y, Bao WQ, Tong Y, Ni SB, Liu JP, Zhao B
Journal of receptor and signal transduction research 2022 Feb;42(1):1-8
Journal of receptor and signal transduction research 2022 Feb;42(1):1-8
FGD3 binds with HSF4 to suppress p65 expression and inhibit pancreatic cancer progression.
Guo F, Cheng X, Jing B, Wu H, Jin X
Oncogene 2022 Feb;41(6):838-851
Oncogene 2022 Feb;41(6):838-851
The keratin 17/YAP/IL6 axis contributes to E-cadherin loss and aggressiveness of diffuse gastric cancer.
Li M, Rao X, Cui Y, Zhang L, Li X, Wang B, Zheng Y, Teng L, Zhou T, Zhuo W
Oncogene 2022 Feb;41(6):770-781
Oncogene 2022 Feb;41(6):770-781
MiR-4521 plays a tumor repressive role in growth and metastasis of hepatocarcinoma cells by suppressing phosphorylation of FAK/AKT pathway via targeting FAM129A.
Ayesha M, Majid A, Zhao D, Greenaway FT, Yan N, Liu Q, Liu S, Sun MZ
Journal of advanced research 2022 Feb;36:147-161
Journal of advanced research 2022 Feb;36:147-161
Dihydrotestosterone through blockade of TGF-β/Smad signaling mediates the anti-fibrosis effect under hypoxia in canine Sertoli cells.
Xiao L, Wang Z, Lu N, Wei H, Kang J, Yuan M, Sheng X, Qi X, Xing K, Guo Y, Wang X, Zhao J, Gao Y, Ni H
The Journal of steroid biochemistry and molecular biology 2022 Feb;216:106041
The Journal of steroid biochemistry and molecular biology 2022 Feb;216:106041
Cancer-associated fibroblasts promote tumor progression by lncRNA-mediated RUNX2/GDF10 signaling in oral squamous cell carcinoma.
Zhang D, Song Y, Li D, Liu X, Pan Y, Ding L, Shi G, Wang Y, Ni Y, Hou Y
Molecular oncology 2022 Feb;16(3):780-794
Molecular oncology 2022 Feb;16(3):780-794
Ubiquitin-specific peptidase 2 inhibits epithelial-mesenchymal transition in clear cell renal cell carcinoma metastasis by downregulating the NF-κB pathway.
Duan J, Jin M, Yang D, Shi J, Gao J, Guo D, Tang H, Zhang S, Qiao B
Bioengineered 2022 Feb;13(2):4455-4467
Bioengineered 2022 Feb;13(2):4455-4467
Foxhead box D1 promotes the partial epithelial-to-mesenchymal transition of laryngeal squamous cell carcinoma cells via transcriptionally activating the expression of zinc finger protein 532.
Fan L, Wang J, Deng P, Wang Y, Zhang A, Yang M, Zeng G
Bioengineered 2022 Feb;13(2):3057-3069
Bioengineered 2022 Feb;13(2):3057-3069
Hyperglycemia induces miR-26-5p down-regulation to overexpress PFKFB3 and accelerate epithelial-mesenchymal transition in gastric cancer.
He X, Cheng X, Ding J, Xiong M, Chen B, Cao G
Bioengineered 2022 Feb;13(2):2902-2917
Bioengineered 2022 Feb;13(2):2902-2917
MiR-187 regulates the proliferation, migration and invasion of human trophoblast cells by repressing BCL6-mediated activation of PI3K/AKT signaling.
Chen X, Song QL, Ji R, Wang JY, Li ZH, Guo D, Yin TL, Wang SJ, Yang J
Placenta 2022 Feb;118:20-31
Placenta 2022 Feb;118:20-31
HDAC9 Contributes to Serous Ovarian Cancer Progression through Regulating Epithelial-Mesenchymal Transition.
Xu L, Wang J, Liu B, Fu J, Zhao Y, Yu S, Shen L, Yan X, Su J
Biomedicines 2022 Feb 3;10(2)
Biomedicines 2022 Feb 3;10(2)
Norepinephrine promotes glioma cell migration through up-regulating the expression of Twist1.
Wang X, Wang Y, Xie F, Song ZT, Zhang ZQ, Zhao Y, Wang SD, Hu H, Zhang YS, Qian LJ
BMC cancer 2022 Feb 26;22(1):213
BMC cancer 2022 Feb 26;22(1):213
Numb-PRRL promotes TGF-β1- and EGF-induced epithelial-to-mesenchymal transition in pancreatic cancer.
Sheng W, Tang J, Cao R, Shi X, Ma Y, Dong M
Cell death & disease 2022 Feb 23;13(2):173
Cell death & disease 2022 Feb 23;13(2):173
YTHDF1 promotes breast cancer progression by facilitating FOXM1 translation in an m6A-dependent manner.
Chen H, Yu Y, Yang M, Huang H, Ma S, Hu J, Xi Z, Guo H, Yao G, Yang L, Huang X, Zhang F, Tan G, Wu H, Zheng W, Li L
Cell & bioscience 2022 Feb 23;12(1):19
Cell & bioscience 2022 Feb 23;12(1):19
ZHX2 inhibits thyroid cancer metastasis through transcriptional inhibition of S100A14.
Zhang Y, Sun M, Gao L, Liang X, Ma C, Lu J, Yue X
Cancer cell international 2022 Feb 12;22(1):76
Cancer cell international 2022 Feb 12;22(1):76
Ginsenoside Rh4 Suppressed Metastasis of Lung Adenocarcinoma via Inhibiting JAK2/STAT3 Signaling.
Zhang Y, Ma P, Duan Z, Liu Y, Mi Y, Fan D
International journal of molecular sciences 2022 Feb 11;23(4)
International journal of molecular sciences 2022 Feb 11;23(4)
FERMT1 contributes to the migration and invasion of nasopharyngeal carcinoma through epithelial-mesenchymal transition and cell cycle arrest.
Li L, Li P, Zhang W, Zhou H, Guo E, Hu G, Zhang L
Cancer cell international 2022 Feb 10;22(1):70
Cancer cell international 2022 Feb 10;22(1):70
CircCERS6 Suppresses the Development of Epithelial Ovarian Cancer Through Mediating miR-630/RASSF8.
Li X, Jiang X, Lu J, Lin Y, Jiang L, Li Y, Wan F, Wang C
Biochemical genetics 2022 Dec;60(6):2611-2629
Biochemical genetics 2022 Dec;60(6):2611-2629
Study on the biological mechanism of urolithin a on nasopharyngeal carcinoma in vitro.
Yang Y, Ren ZZ, Wei WJ, He ZL, Deng YL, Wang Z, Fan YC, Zhou J, Jiang LH
Pharmaceutical biology 2022 Dec;60(1):1566-1577
Pharmaceutical biology 2022 Dec;60(1):1566-1577
Relaxin inhibits renal fibrosis and the epithelial-to-mesenchymal transition via the Wnt/β-catenin signaling pathway.
Feiteng C, Lei C, Deng L, Chaoliang X, Zijie X, Yi S, Minglei S
Renal failure 2022 Dec;44(1):513-524
Renal failure 2022 Dec;44(1):513-524
Cystathionine γ-lyase mediates cell proliferation, migration, and invasion of nasopharyngeal carcinoma.
Zhang Q, Gao Y, Zhang Y, Jing M, Wang D, Wang Y, Khattak S, Qi H, Cai C, Zhang J, Ngowi EE, Khan NH, Li T, Ji A, Jiang Q, Ji X, Li Y, Wu D
Oncogene 2022 Dec;41(49):5238-5252
Oncogene 2022 Dec;41(49):5238-5252
IRF2-ferroptosis related gene is associated with prognosis and EMT in gliomas.
Tong S, Ye L, Xu Y, Sun Q, Gao L, Cai J, Ye Z, Tian D, Chen Q
Translational oncology 2022 Dec;26:101544
Translational oncology 2022 Dec;26:101544
ALG2 inhibits the epithelial-to-mesenchymal transition and stemness of ovarian granulosa cells through the Wnt/β-catenin signaling pathway in polycystic ovary syndrome.
Zheng Q, Liu M, Fu J
Reproductive biology 2022 Dec;22(4):100706
Reproductive biology 2022 Dec;22(4):100706
Transcription factor SP1 and oncoprotein PPP1R13L regulate nicotine-induced epithelial-mesenchymal transition in lung adenocarcinoma via a feedback loop.
Zhang H, Zhang G, Zhang J, Xiao M, Cui S, Wu S, Jin C, Yang J, Lu X
Biochemical pharmacology 2022 Dec;206:115344
Biochemical pharmacology 2022 Dec;206:115344
Artemisitene suppresses rheumatoid arthritis progression via modulating METTL3-mediated N6-methyladenosine modification of ICAM2 mRNA in fibroblast-like synoviocytes.
Chen J, Lin X, He J, Liu D, He L, Zhang M, Luan H, Hu Y, Tao C, Wang Q
Clinical and translational medicine 2022 Dec;12(12):e1148
Clinical and translational medicine 2022 Dec;12(12):e1148
Silencing of lncRNA SNHG17 inhibits the tumorigenesis of epithelial ovarian cancer through regulation of miR-485-5p/AKT1 axis.
Wang W, Yu S, Li W, Hu H, Zou G
Biochemical and biophysical research communications 2022 Dec 31;637:117-126
Biochemical and biophysical research communications 2022 Dec 31;637:117-126
Exosome-transmitted S100A4 induces immunosuppression and non-small cell lung cancer development by activating STAT3.
Wu X, Zhang H, Jiang G, Peng M, Li C, Lu J, Jiang S, Yang X, Jiang Y
Clinical and experimental immunology 2022 Dec 31;210(3):309-320
Clinical and experimental immunology 2022 Dec 31;210(3):309-320
lncRNA ZNRD1-AS1 promotes malignant lung cell proliferation, migration, and angiogenesis via the miR-942/TNS1 axis and is positively regulated by the m(6)A reader YTHDC2.
Wang J, Tan L, Yu X, Cao X, Jia B, Chen R, Li J
Molecular cancer 2022 Dec 30;21(1):229
Molecular cancer 2022 Dec 30;21(1):229
FAT4 activation inhibits epithelial-mesenchymal transition (EMT) by promoting autophagy in H2228/Cer cells.
Yang Y, Li Y, Yang Q, Liu Z, Chang X, Yang H, Liu J, Li Z, Zuo D
Medical oncology (Northwood, London, England) 2022 Dec 28;40(1):64
Medical oncology (Northwood, London, England) 2022 Dec 28;40(1):64
Krüppel-like Factor 13 Promotes HCC Progression by Transcriptional Regulation of HMGCS1-mediated Cholesterol Synthesis.
Chen CC, Xie XM, Zhao XK, Zuo S, Li HY
Journal of clinical and translational hepatology 2022 Dec 28;10(6):1125-1137
Journal of clinical and translational hepatology 2022 Dec 28;10(6):1125-1137
Increased expression of miR-194-5p through the circPVRL3/miR-194-5p/SOCS2 axis promotes proliferation and metastasis in pancreatic ductal adenocarcinoma by activating the PI3K/AKT signaling pathway.
Chi B, Zheng Y, Xie F, Fu W, Wang X, Gu J, Yang J, Yin J, Cai L, Tang P, Li J, Guo S, Wang H
Cancer cell international 2022 Dec 20;22(1):415
Cancer cell international 2022 Dec 20;22(1):415
A multifunctional black phosphorus-based adhesive patch intrinsically induces partial EMT for effective burn wound healing.
Wang X, Tang X, Li N, Sun Y, Yu R, Zhang J, Li D, Yang B, Sun H
Biomaterials science 2022 Dec 20;11(1):235-247
Biomaterials science 2022 Dec 20;11(1):235-247
Extracellular matrix modulating enzyme functionalized biomimetic Au nanoplatform-mediated enhanced tumor penetration and synergistic antitumor therapy for pancreatic cancer.
Yang XY, Zhang JG, Zhou QM, Yu JN, Lu YF, Wang XJ, Zhou JP, Ding XF, Du YZ, Yu RS
Journal of nanobiotechnology 2022 Dec 10;20(1):524
Journal of nanobiotechnology 2022 Dec 10;20(1):524
Novel shikonin derivatives suppress cell proliferation, migration and induce apoptosis in human triple-negative breast cancer cells via regulating PDK1/PDHC axis.
Chen Q, Han H, Lin F, Yang L, Feng L, Lai X, Wen Z, Yang M, Wang C, Ma Y, Yin T, Lu G, Lin H, Qi J, Yang Y
Life sciences 2022 Dec 1;310:121077
Life sciences 2022 Dec 1;310:121077
Identification of endocrine-disrupting chemicals targeting the genes and pathways of genital anomalies in males.
Zhou X, Zhang X, Zhou X, Abulimiti G, Wang Y, Zhang Q, Cong R, Ji C, Luan J, Yao L, Yang J, Song N
Ecotoxicology and environmental safety 2022 Dec 1;247:114241
Ecotoxicology and environmental safety 2022 Dec 1;247:114241
YAP1-TEAD1 mediates the perineural invasion of prostate cancer cells induced by cancer-associated fibroblasts.
Shen T, Li Y, Wang D, Su Y, Li G, Shang Z, Niu Y, Tan X
Biochimica et biophysica acta. Molecular basis of disease 2022 Dec 1;1868(12):166540
Biochimica et biophysica acta. Molecular basis of disease 2022 Dec 1;1868(12):166540
Suppression of rhomboid domain-containing 1 produces anticancer effects in pancreatic adenocarcinoma through affection of the AKT/GSK-3β/β-catenin pathway.
Jiang J, Cheng Y, Dai S, Zou B, Guo X
Environmental toxicology 2022 Aug;37(8):1944-1956
Environmental toxicology 2022 Aug;37(8):1944-1956
XIST sponges miR-320d to promote chordoma progression by regulating ARF6.
Wang Y, Tang Z, Guo W
Journal of bone oncology 2022 Aug;35:100447
Journal of bone oncology 2022 Aug;35:100447
Downstream Neighbor of Son Overexpression is Associated With Breast Cancer Progression and a Poor Prognosis.
Qi Y, Wu H, Liu C, Zheng D, Yan C, Hu W, Zhang X, Dai X
Journal of breast cancer 2022 Aug;25(4):327-343
Journal of breast cancer 2022 Aug;25(4):327-343
Agmatinase facilitates the tumorigenesis of pancreatic adenocarcinoma through the TGFβ/Smad pathway.
Zhang Y, Cao L, Xie Y, Wang C, Liu X, Zhang X, Chen J
Experimental and therapeutic medicine 2022 Aug;24(2):490
Experimental and therapeutic medicine 2022 Aug;24(2):490
Nav1.6 promotes the progression of human follicular thyroid carcinoma cells via JAK-STAT signaling pathway.
Li H, Liu J, Fan N, Wang H, Thomas AM, Yan Q, Li S, Qin H
Pathology, research and practice 2022 Aug;236:153984
Pathology, research and practice 2022 Aug;236:153984
Nascent Proteome and Glycoproteome Reveal the Inhibition Role of ALG1 in Hepatocellular Carcinoma Cell Migration.
Cao X, Shao Y, Meng P, Cao Z, Yan G, Yao J, Zhou X, Liu C, Zhang L, Shu H, Lu H
Phenomics (Cham, Switzerland) 2022 Aug;2(4):230-241
Phenomics (Cham, Switzerland) 2022 Aug;2(4):230-241
HIF-1α induced NID1 expression promotes pulmonary metastases via the PI3K-AKT pathway in salivary gland adenoid cystic carcinoma.
Han N, Li X, Wang Y, Li H, Zhang C, Zhao X, Zhang Z, Ruan M, Zhang C
Oral oncology 2022 Aug;131:105940
Oral oncology 2022 Aug;131:105940
PEBP4 Directs the Malignant Behavior of Hepatocellular Carcinoma Cells via Regulating mTORC1 and mTORC2.
Chen Q, Jin J, Guo W, Tang Z, Luo Y, Ying Y, Lin H, Luo Z
International journal of molecular sciences 2022 Aug 8;23(15)
International journal of molecular sciences 2022 Aug 8;23(15)
Long noncoding RNA CERS6-AS1 modulates glucose metabolism and tumor progression in hepatocellular carcinoma by promoting the MDM2/p53 signaling pathway.
Xu B, Wei Y, Liu F, Li L, Zhou S, Peng Y, Li B
Cell death discovery 2022 Aug 4;8(1):348
Cell death discovery 2022 Aug 4;8(1):348
Hypermethylation of PRKCZ Regulated by E6 Inhibits Invasion and EMT via Cdc42 in HPV-Related Head and Neck Squamous Cell Carcinoma.
Wang HF, Jiang J, Wu JS, Zhang M, Pang X, Dai L, Tang YL, Liang XH
Cancers 2022 Aug 27;14(17)
Cancers 2022 Aug 27;14(17)
Discovery of a Novel Small-Molecule Inhibitor Disrupting TRBP-Dicer Interaction against Hepatocellular Carcinoma via the Modulation of microRNA Biogenesis.
Peng T, He Y, Wang T, Yu J, Ma X, Zhou Z, Sheng Y, Li L, Peng H, Li S, Zou J, Yuan Y, Zhao Y, Shi H, Li F, Liu W, Hu K, Lu X, Zhang G, Wang F
Journal of medicinal chemistry 2022 Aug 25;65(16):11010-11033
Journal of medicinal chemistry 2022 Aug 25;65(16):11010-11033
Exosomal miR-155-5p derived from glioma stem-like cells promotes mesenchymal transition via targeting ACOT12.
Bao Z, Zhang N, Niu W, Mu M, Zhang X, Hu S, Niu C
Cell death & disease 2022 Aug 19;13(8):725
Cell death & disease 2022 Aug 19;13(8):725
FAM107A Inactivation Associated with Promoter Methylation Affects Prostate Cancer Progression through the FAK/PI3K/AKT Pathway.
Ke S, Liu Z, Wang Q, Zhai G, Shao H, Yu X, Guo J
Cancers 2022 Aug 13;14(16)
Cancers 2022 Aug 13;14(16)
miR-596-3p suppresses brain metastasis of non-small cell lung cancer by modulating YAP1 and IL-8.
Li C, Zheng H, Xiong J, Huang Y, Li H, Jin H, Ai S, Wang Y, Su T, Sun G, Xiao X, Fu T, Wang Y, Gao X, Liang P
Cell death & disease 2022 Aug 12;13(8):699
Cell death & disease 2022 Aug 12;13(8):699
PDCD10 promotes the aggressive behaviors of pituitary adenomas by up-regulating CXCR2 and activating downstream AKT/ERK signaling.
Liu J, Wang J, Tian W, Xu Y, Li R, Zhao K, You C, Zhu Y, Bartsch JW, Niu H, Zhang H, Shu K, Lei T
Aging 2022 Aug 11;14(15):6066-6080
Aging 2022 Aug 11;14(15):6066-6080
Jianpi Huayu decoction inhibits the epithelial-mesenchymal transition of hepatocellular carcinoma cells by suppressing exosomal miR-23a-3p/Smad signaling.
Xie CF, Feng KL, Wang JN, Luo R, Fang CK, Zhang Y, Shen CP, Zhong C
Journal of ethnopharmacology 2022 Aug 10;294:115360
Journal of ethnopharmacology 2022 Aug 10;294:115360
EML4-ALK G1202R mutation induces EMT and confers resistance to ceritinib in NSCLC cells via activation of STAT3/Slug signaling.
Shen J, Meng Y, Wang K, Gao M, Du J, Wang J, Li Z, Zuo D, Wu Y
Cellular signalling 2022 Apr;92:110264
Cellular signalling 2022 Apr;92:110264
Interleukin-17A mediates tobacco smoke-induced lung cancer epithelial-mesenchymal transition through transcriptional regulation of ΔNp63α on miR-19.
Xie C, Zhu J, Huang C, Yang X, Wang X, Meng Y, Geng S, Wu J, Shen H, Hu Z, Meng Z, Li X, Zhong C
Cell biology and toxicology 2022 Apr;38(2):273-289
Cell biology and toxicology 2022 Apr;38(2):273-289
Tumor-specific nitric oxide generator to amplify peroxynitrite based on highly penetrable nanoparticles for metastasis inhibition and enhanced cancer therapy.
Shi M, Zhang J, Wang Y, Peng C, Hu H, Qiao M, Zhao X, Chen D
Biomaterials 2022 Apr;283:121448
Biomaterials 2022 Apr;283:121448
Terpinen-4-ol inhibits the proliferation and mobility of pancreatic cancer cells by downregulating Rho-associated coiled-coil containing protein kinase 2.
Cao W, Tian R, Pan R, Sun B, Xiao C, Chen Y, Zeng Z, Lei S
Bioengineered 2022 Apr;13(4):8643-8656
Bioengineered 2022 Apr;13(4):8643-8656
Ginsenoside Rh4 Suppresses Metastasis of Gastric Cancer via SIX1-Dependent TGF-β/Smad2/3 Signaling Pathway.
Jiang H, Ma P, Duan Z, Liu Y, Shen S, Mi Y, Fan D
Nutrients 2022 Apr 9;14(8)
Nutrients 2022 Apr 9;14(8)
TIM-1 promotes proliferation and metastasis, and inhibits apoptosis, in cervical cancer through the PI3K/AKT/p53 pathway.
Chen L, Qing J, Xiao Y, Huang X, Chi Y, Chen Z
BMC cancer 2022 Apr 7;22(1):370
BMC cancer 2022 Apr 7;22(1):370
Brusatol inhibits the growth of renal cell carcinoma by regulating the PTEN/PI3K/AKT pathway.
Wang T, Chen Z, Chen H, Yu X, Wang L, Liu X
Journal of ethnopharmacology 2022 Apr 24;288:115020
Journal of ethnopharmacology 2022 Apr 24;288:115020
Overexpression of GATA5 Inhibits Prostate Cancer Progression by Regulating PLAGL2 via the FAK/PI3K/AKT Pathway.
Wang Q, Liu Z, Zhai G, Yu X, Ke S, Shao H, Guo J
Cancers 2022 Apr 21;14(9)
Cancers 2022 Apr 21;14(9)
HGF/c-Met pathway facilitates the perineural invasion of pancreatic cancer by activating the mTOR/NGF axis.
Qin T, Xiao Y, Qian W, Wang X, Gong M, Wang Q, An R, Han L, Duan W, Ma Q, Wang Z
Cell death & disease 2022 Apr 21;13(4):387
Cell death & disease 2022 Apr 21;13(4):387
Epigenetic Deregulation of Protein Tyrosine Kinase 6 Promotes Carcinogenesis of Oral Squamous Cell Carcinoma.
Hsieh YP, Chen KC, Chen MY, Huang LY, Su AY, Chiang WF, Huang WT, Huang TT
International journal of molecular sciences 2022 Apr 19;23(9)
International journal of molecular sciences 2022 Apr 19;23(9)
METTL3-mediated m6A modification of STEAP2 mRNA inhibits papillary thyroid cancer progress by blocking the Hedgehog signaling pathway and epithelial-to-mesenchymal transition.
Zhu Y, Peng X, Zhou Q, Tan L, Zhang C, Lin S, Long M
Cell death & disease 2022 Apr 18;13(4):358
Cell death & disease 2022 Apr 18;13(4):358
Hexachlorophene, a selective SHP2 inhibitor, suppresses proliferation and metastasis of KRAS-mutant NSCLC cells by inhibiting RAS/MEK/ERK and PI3K/AKT signaling pathways.
Fu NJ, Xi RY, Shi XK, Li RZ, Zhang ZH, Li LY, Zhang GL, Wang F
Toxicology and applied pharmacology 2022 Apr 15;441:115988
Toxicology and applied pharmacology 2022 Apr 15;441:115988
Silencing of Nudix type 5 represses proliferation and invasion and enhances chemosensitivity of gastric carcinoma cells by affecting the AKT/GSK-3β/β-catenin pathway.
Tan D, Zhang Y
Toxicology and applied pharmacology 2022 Apr 15;441:115968
Toxicology and applied pharmacology 2022 Apr 15;441:115968
SMAD3 and FTO are involved in miR-5581-3p-mediated inhibition of cell migration and proliferation in bladder cancer.
Sun J, Ma X, Ying Y, Wang W, Shen H, Wang S, Xie H, Yi J, Zhan W, Li J, Liu B
Cell death discovery 2022 Apr 13;8(1):199
Cell death discovery 2022 Apr 13;8(1):199
Metabolites and Biomarker Compounds of Neurodegenerative Diseases in Cerebrospinal Fluid.
Wakamatsu K, Chiba Y, Murakami R, Miyai Y, Matsumoto K, Kamada M, Nonaka W, Uemura N, Yanase K, Ueno M
Metabolites 2022 Apr 12;12(4)
Metabolites 2022 Apr 12;12(4)
m6A Modification-Mediated DUXAP8 Regulation of Malignant Phenotype and Chemotherapy Resistance of Hepatocellular Carcinoma Through miR-584-5p/MAPK1/ERK Pathway Axis.
Liu Z, Lu J, Fang H, Sheng J, Cui M, Yang Y, Tang B, Zhang X
Frontiers in cell and developmental biology 2021;9:783385
Frontiers in cell and developmental biology 2021;9:783385
Resveratrol-Loaded TPGS-Resveratrol-Solid Lipid Nanoparticles for Multidrug-Resistant Therapy of Breast Cancer: In Vivo and In Vitro Study.
Wang W, Zhou M, Xu Y, Peng W, Zhang S, Li R, Zhang H, Zhang H, Cheng S, Wang Y, Wei X, Yue C, Yang Q, Chen C
Frontiers in bioengineering and biotechnology 2021;9:762489
Frontiers in bioengineering and biotechnology 2021;9:762489
PRDM16 Inhibits Cell Proliferation and Migration via Epithelial-to-Mesenchymal Transition by Directly Targeting Pyruvate Carboxylase in Papillary Thyroid Cancer.
Liu WL, Guan Q, Wen D, Ma B, Xu WB, Hu JQ, Wei WJ, Li DS, Wang Y, Xiang J, Liao T, Ji QH
Frontiers in cell and developmental biology 2021;9:723777
Frontiers in cell and developmental biology 2021;9:723777
Circular RNA circSIPA1L1 Contributes to Osteosarcoma Progression Through the miR-411-5p/RAB9A Signaling Pathway.
Xu Y, Yao T, Ni H, Zheng R, Huang K, Huang Y, Gao J, Qiao D, Shen S, Ma J
Frontiers in cell and developmental biology 2021;9:642605
Frontiers in cell and developmental biology 2021;9:642605
MicroRNA-15a Carried by Mesenchymal Stem Cell-Derived Extracellular Vesicles Inhibits the Immune Evasion of Colorectal Cancer Cells by Regulating the KDM4B/HOXC4/PD-L1 Axis.
Liu L, Yu T, Jin Y, Mai W, Zhou J, Zhao C
Frontiers in cell and developmental biology 2021;9:629893
Frontiers in cell and developmental biology 2021;9:629893
ENC1 Facilitates Colorectal Carcinoma Tumorigenesis and Metastasis via JAK2/STAT5/AKT Axis-Mediated Epithelial Mesenchymal Transition and Stemness.
Cui Y, Yang J, Bai Y, Li Q, Yao Y, Liu C, Wu F, Zhang J, Zhang Y
Frontiers in cell and developmental biology 2021;9:616887
Frontiers in cell and developmental biology 2021;9:616887
Transcription Factors BARX1 and DLX4 Contribute to Progression of Clear Cell Renal Cell Carcinoma via Promoting Proliferation and Epithelial-Mesenchymal Transition.
Sun G, Ge Y, Zhang Y, Yan L, Wu X, Ouyang W, Wang Z, Ding B, Zhang Y, Long G, Liu M, Shi R, Zhou H, Chen Z, Ye Z
Frontiers in molecular biosciences 2021;8:626328
Frontiers in molecular biosciences 2021;8:626328
Acyl-CoA Thioesterase 7 is Transcriptionally Activated by Krüppel-Like Factor 13 and Promotes the Progression of Hepatocellular Carcinoma.
Xie X, Chen C, Feng S, Zuo S, Zhao X, Li H
Journal of hepatocellular carcinoma 2021;8:1623-1641
Journal of hepatocellular carcinoma 2021;8:1623-1641
Inositol Hexakisphosphate and Inositol Enhance the Inhibition of Colorectal Cancer Growth and Liver Metastasis by Capecitabine in a Mouse Model.
Li C, Ci Y, Liu X, Chen C, Liu C, Li X, Li Q, Song Y
Nutrition and cancer 2021;73(11-12):2306-2314
Nutrition and cancer 2021;73(11-12):2306-2314
Qingjie Fuzheng Granule Inhibits EMT and Induces Autophagy in Colorectal Cancer via mTOR Signaling Pathways.
Zhu X, Chen Y, Lin M, Huang B, Lin J
Evidence-based complementary and alternative medicine : eCAM 2021;2021:9950499
Evidence-based complementary and alternative medicine : eCAM 2021;2021:9950499
Network Pharmacology-Based Mechanistic Investigation of Jinshui Huanxian Formula Acting on Idiopathic Pulmonary Fibrosis.
Liu T, Xu P, Qi S, Ke S, Hu Q, Zhao P, Li J
Evidence-based complementary and alternative medicine : eCAM 2021;2021:8634705
Evidence-based complementary and alternative medicine : eCAM 2021;2021:8634705
ARHGEF10L Promotes Cervical Tumorigenesis via RhoA-Mediated Signaling.
Tang J, Fang K, Li C, Chang X
Evidence-based complementary and alternative medicine : eCAM 2021;2021:6683264
Evidence-based complementary and alternative medicine : eCAM 2021;2021:6683264
lncRNA LINC01296 Promotes Oral Squamous Cell Carcinoma Development by Binding with SRSF1.
Zhang Y, Wang A, Zhang X, Wang X, Zhang J, Ma J
BioMed research international 2021;2021:6661520
BioMed research international 2021;2021:6661520
Therapeutic Potential of RTA 404 in Human Brain Malignant Glioma Cell Lines via Cell Cycle Arrest via p21/AKT Signaling.
Tsai TH, Lieu AS, Wang YW, Yang SF, Hsu YC, Lin CL
BioMed research international 2021;2021:5552226
BioMed research international 2021;2021:5552226
BOP1 Used as a Novel Prognostic Marker and Correlated with Tumor Microenvironment in Pan-Cancer.
Li W, Song P, Zhao M, Gao L, Xie J, You C
Journal of oncology 2021;2021:3603030
Journal of oncology 2021;2021:3603030
Cysteine-Rich Intestinal Protein 1 Served as an Epithelial Ovarian Cancer Marker via Promoting Wnt/β-Catenin-Mediated EMT and Tumour Metastasis.
Liu Y, Li W, Luo J, Wu Y, Xu Y, Chen T, Zhang W, Fu F
Disease markers 2021;2021:3566749
Disease markers 2021;2021:3566749
Trefoil Factor 3 Inhibits Thyroid Cancer Cell Progression Related to IL-6/JAK/STAT3 Signaling Pathway.
Xin Y, Shang X, Sun X, Liu Y, Xu G, Xue G
Evidence-based complementary and alternative medicine : eCAM 2021;2021:2130229
Evidence-based complementary and alternative medicine : eCAM 2021;2021:2130229
YY1-modulated long non-coding RNA SNHG12 promotes gastric cancer metastasis by activating the miR-218-5p/YWHAZ axis.
Zhang T, Beeharry MK, Wang Z, Zhu Z, Li J, Li C
International journal of biological sciences 2021;17(7):1629-1643
International journal of biological sciences 2021;17(7):1629-1643
ITGB1 enhances the Radioresistance of human Non-small Cell Lung Cancer Cells by modulating the DNA damage response and YAP1-induced Epithelial-mesenchymal Transition.
Li Y, Sun C, Tan Y, Zhang H, Li Y, Zou H
International journal of biological sciences 2021;17(2):635-650
International journal of biological sciences 2021;17(2):635-650
miR-34a-5p functions as a tumor suppressor in head and neck squamous cell cancer progression by targeting Flotillin-2.
Li X, Zhao S, Fu Y, Zhang P, Zhang Z, Cheng J, Liu L, Jiang H
International journal of biological sciences 2021;17(15):4327-4339
International journal of biological sciences 2021;17(15):4327-4339
Cyclovirobuxine inhibits the progression of clear cell renal cell carcinoma by suppressing the IGFBP3-AKT/STAT3/MAPK-Snail signalling pathway.
Liu Y, Lv H, Li X, Liu J, Chen S, Chen Y, Jin Y, An R, Yu S, Wang Z
International journal of biological sciences 2021;17(13):3522-3537
International journal of biological sciences 2021;17(13):3522-3537
Downregulation of m(6)A Reader YTHDC2 Promotes the Proliferation and Migration of Malignant Lung Cells via CYLD/NF-κB Pathway.
Wang J, Tan L, Jia B, Yu X, Yao R, OUYang N, Yu X, Cao X, Tong J, Chen T, Chen R, Li J
International journal of biological sciences 2021;17(10):2633-2651
International journal of biological sciences 2021;17(10):2633-2651
Delivery of Rapamycin by Liposomes Synergistically Enhances the Chemotherapy Effect of 5-Fluorouracil on Colorectal Cancer.
Chen YQ, Zhu WT, Lin CY, Yuan ZW, Li ZH, Yan PK
International journal of nanomedicine 2021;16:269-281
International journal of nanomedicine 2021;16:269-281
TEAD4 as a Prognostic Marker Promotes Cell Migration and Invasion of Urinary Bladder Cancer via EMT.
Huang Z, Yan Y, Tang P, Cai J, Cao X, Wang Z, Zhang F, Shen B
OncoTargets and therapy 2021;14:937-949
OncoTargets and therapy 2021;14:937-949
LncRNA UCID Promotes Hepatocellular Carcinoma Metastasis via Stabilization of Snail.
Yuan S, Si W, Zhuang K, Li Y, Zhang Y, Liu J, Yang L, Zhang X
OncoTargets and therapy 2021;14:725-736
OncoTargets and therapy 2021;14:725-736
A c-Met Inhibitor Suppresses Osteosarcoma Progression via the ERK1/2 Pathway in Human Osteosarcoma Cells.
Chen W, Wu S, Huang Y, Zhang T, Dong H, Zheng X, Chen T, Gong X, Liu G, Zhao X
OncoTargets and therapy 2021;14:4791-4804
OncoTargets and therapy 2021;14:4791-4804
XBP1s Acts as a Tumor Suppressor to Inhibit the EMT Process and Metastasis of Papillary Thyroid Cancer.
Yang W, Xu X, Xu M, Zhou J, Xi Z, Guo H, Ming J, Huang T
OncoTargets and therapy 2021;14:2339-2348
OncoTargets and therapy 2021;14:2339-2348
FUT7 Promotes the Epithelial-Mesenchymal Transition and Immune Infiltration in Bladder Urothelial Carcinoma.
Liu M, Zheng Q, Chen S, Liu J, Li S
Journal of inflammation research 2021;14:1069-1084
Journal of inflammation research 2021;14:1069-1084
LncRNA IGFL2-AS1 Promotes the Proliferation, Migration, and Invasion of Colon Cancer Cells and is Associated with Patient Prognosis.
Cen X, Huang Y, Lu Z, Shao W, Zhuo C, Bao C, Feng S, Wei C, Tang X, Cen L, Guo W, Tian X, Tang Q, Huang X
Cancer management and research 2021;13:5957-5968
Cancer management and research 2021;13:5957-5968
Plakophilin-2 Promotes Lung Adenocarcinoma Development via Enhancing Focal Adhesion and Epithelial-Mesenchymal Transition.
Wu Y, Liu L, Shen X, Liu W, Ma R
Cancer management and research 2021;13:559-570
Cancer management and research 2021;13:559-570
ARRB1 Drives Gallbladder Cancer Progression by Facilitating TAK1/MAPK Signaling Activation.
Zhang X, Kong Z, Xu X, Yun X, Chao J, Ding D, Li T, Gao Y, Guan N, Zhu C, Qin X
Journal of Cancer 2021;12(7):1926-1935
Journal of Cancer 2021;12(7):1926-1935
GTW inhibits the Epithelial to Mesenchymal Transition of Epithelial Ovarian Cancer via ILK/AKT/GSK3β/Slug Signalling Pathway.
Feng Y, Le F, Tian P, Zhong Y, Zhan F, Huang G, Hu H, Chen T, Tan B
Journal of Cancer 2021;12(5):1386-1397
Journal of Cancer 2021;12(5):1386-1397
JMJD8 Promotes Malignant Progression of Lung Cancer by Maintaining EGFR Stability and EGFR/PI3K/AKT Pathway Activation.
Zhang B, Zhang Y, Jiang X, Su H, Wang Q, Wudu M, Jiang J, Ren H, Xu Y, Liu Z, Qiu X
Journal of Cancer 2021;12(4):976-987
Journal of Cancer 2021;12(4):976-987
Deltex3 inhibits Epithelial Mesenchymal Transition in Papillary Thyroid Carcinoma via promoting ubiquitination of XRCC5 to regulate the AKT signal pathway.
Wang L, Huang Y, Liu C, Guo M, Ma Z, He J, Wang A, Sun X, Liu Z
Journal of Cancer 2021;12(3):860-873
Journal of Cancer 2021;12(3):860-873
Keratin 80 regulated by miR-206/ETS1 promotes tumor progression via the MEK/ERK pathway in ovarian cancer.
Liu O, Wang C, Wang S, Hu Y, Gou R, Dong H, Li S, Li X, Lin B
Journal of Cancer 2021;12(22):6835-6850
Journal of Cancer 2021;12(22):6835-6850
SNX-2112 Induces Apoptosis and Inhibits Proliferation, Invasion, and Migration of Non-Small Cell Lung Cancer by Downregulating Epithelial-Mesenchymal Transition via the Wnt/β-Catenin Signaling Pathway.
Cheng X, Qin L, Deng L, Zhu X, Li Y, Wu X, Zheng Y
Journal of Cancer 2021;12(19):5825-5837
Journal of Cancer 2021;12(19):5825-5837
Elevated HNF1A expression promotes radiation-resistance via driving PI3K/AKT signaling pathway in esophageal squamous cell carcinoma cells.
Zou N, Zhang X, Li S, Li Y, Zhao Y, Yang X, Zhu S
Journal of Cancer 2021;12(16):5013-5024
Journal of Cancer 2021;12(16):5013-5024
Demethylzelasteral inhibits proliferation and EMT via repressing Wnt/β-catenin signaling in esophageal squamous cell carcinoma.
Yu J, Wang W, Liu B, Gu J, Chen S, Cui Y, Sun G
Journal of Cancer 2021;12(13):3967-3975
Journal of Cancer 2021;12(13):3967-3975
Dextran Sulfate Effects EMT of Human Gastric Cancer Cells by Reducing HIF-1α/ TGF-β.
Huang YN, Xu YY, Ma Q, Li MQ, Guo JX, Wang X, Jin X, Shang J, Jiao LX
Journal of Cancer 2021;12(11):3367-3377
Journal of Cancer 2021;12(11):3367-3377
Induction of Mitosis Delay and Apoptosis by CDDO-TFEA in Glioblastoma Multiforme.
Tsai TH, Lieu AS, Huang TY, Kwan AL, Lin CL, Hsu YC
Frontiers in pharmacology 2021;12:756228
Frontiers in pharmacology 2021;12:756228
Inhibitory Effect of Dihydroartemisinin on the Proliferation and Migration of Melanoma Cells and Experimental Lung Metastasis From Melanoma in Mice.
Zhang Q, Jin L, Jin Q, Wei Q, Sun M, Yue Q, Liu H, Li F, Li H, Ren X, Jin G
Frontiers in pharmacology 2021;12:727275
Frontiers in pharmacology 2021;12:727275
Association of Pericyte Loss With Microthrombosis After Subarachnoid Hemorrhage in ApoE-Deficient Mice.
Pang J, Wu Y, Peng J, Yang P, Chen L, Jiang Y
Frontiers in neurology 2021;12:726520
Frontiers in neurology 2021;12:726520
CXCL5 Downregulation in Villous Tissue Is Correlated With Recurrent Spontaneous Abortion.
Zhang S, Ding J, Wang J, Yin T, Zhang Y, Yang J
Frontiers in immunology 2021;12:717483
Frontiers in immunology 2021;12:717483
Decreased USP2a Expression Inhibits Trophoblast Invasion and Associates With Recurrent Miscarriage.
Wang J, Ding J, Zhang S, Chen X, Yan S, Zhang Y, Yin T
Frontiers in immunology 2021;12:717370
Frontiers in immunology 2021;12:717370
Oxymatrine Synergistically Enhances Doxorubicin Anticancer Effects in Colorectal Cancer.
Pan D, Zhang W, Zhang N, Xu Y, Chen Y, Peng J, Chen Y, Zhang Y, Shen X
Frontiers in pharmacology 2021;12:673432
Frontiers in pharmacology 2021;12:673432
Autophagic Inhibition of Caveolin-1 by Compound Phyllanthus urinaria L. Activates Ubiquitination and Proteasome Degradation of β-catenin to Suppress Metastasis of Hepatitis B-Associated Hepatocellular Carcinoma.
Huang D, Yang B, Yao Y, Liao M, Zhang Y, Zeng Y, Zhang F, Wang N, Tong G
Frontiers in pharmacology 2021;12:659325
Frontiers in pharmacology 2021;12:659325
PLAU Promotes Cell Proliferation and Epithelial-Mesenchymal Transition in Head and Neck Squamous Cell Carcinoma.
Chen G, Sun J, Xie M, Yu S, Tang Q, Chen L
Frontiers in genetics 2021;12:651882
Frontiers in genetics 2021;12:651882
Molecular Subtypes Based on the Stemness Index Predict Prognosis in Glioma Patients.
Tan J, Zhu H, Tang G, Liu H, Wanggou S, Cao Y, Xin Z, Zhou Q, Zhan C, Wu Z, Guo Y, Jiang Z, Zhao M, Ren C, Jiang X, Yin W
Frontiers in genetics 2021;12:616507
Frontiers in genetics 2021;12:616507
Extracellular vesicles derived from M1 macrophages deliver miR-146a-5p and miR-146b-5p to suppress trophoblast migration and invasion by targeting TRAF6 in recurrent spontaneous abortion.
Ding J, Zhang Y, Cai X, Zhang Y, Yan S, Wang J, Zhang S, Yin T, Yang C, Yang J
Theranostics 2021;11(12):5813-5830
Theranostics 2021;11(12):5813-5830
Epigenetically silenced linc00261 contributes to the metastasis of hepatocellular carcinoma via inducing the deficiency of FOXA2 transcription.
Chen Z, Xiang L, Hu Z, Ou H, Liu X, Yu L, Chen W, Jiang L, Yu Q, Fang Y, Xu Y, Liu Q, Huang Y, Li X, Yang D
American journal of cancer research 2021;11(1):277-296
American journal of cancer research 2021;11(1):277-296
PKM2 Is the Target of a Multi-Herb-Combined Decoction During the Inhibition of Gastric Cancer Progression.
Sun Q, Yuan M, Wang H, Zhang X, Zhang R, Wang H, Chen X, Zhu M, Liu S, Wu J
Frontiers in oncology 2021;11:767116
Frontiers in oncology 2021;11:767116
Long Non-Coding RNA CCAT2 Activates RAB14 and Acts as an Oncogene in Colorectal Cancer.
Wang D, Li Z, Yin H
Frontiers in oncology 2021;11:751903
Frontiers in oncology 2021;11:751903
Honokiol Suppresses Perineural Invasion of Pancreatic Cancer by Inhibiting SMAD2/3 Signaling.
Qin T, Li J, Xiao Y, Wang X, Gong M, Wang Q, Zhu Z, Zhang S, Zhang W, Cao F, Han L, Wang Z, Ma Q, Sha H
Frontiers in oncology 2021;11:728583
Frontiers in oncology 2021;11:728583
Siglec-15 Promotes Tumor Progression in Osteosarcoma via DUSP1/MAPK Pathway.
Fan MK, Zhang GC, Chen W, Qi LL, Xie MF, Zhang YY, Wang L, Zhang Q
Frontiers in oncology 2021;11:710689
Frontiers in oncology 2021;11:710689
YBX1 Enhances Metastasis and Stemness by Transcriptionally Regulating MUC1 in Lung Adenocarcinoma.
Xie Q, Zhao S, Liu W, Cui Y, Li F, Li Z, Guo T, Yu W, Guo W, Deng W, Gu C
Frontiers in oncology 2021;11:702491
Frontiers in oncology 2021;11:702491
Photobiomodulation With Blue Laser Inhibits Bladder Cancer Progression.
Xia Y, Yu W, Cheng F, Rao T, Ruan Y, Yuan R, Ning J, Zhou X, Lin F, Zheng D
Frontiers in oncology 2021;11:701122
Frontiers in oncology 2021;11:701122
TRIM50 Suppresses Pancreatic Cancer Progression and Reverses the Epithelial-Mesenchymal Transition via Facilitating the Ubiquitous Degradation of Snail1.
Li R, Zhu L, Peng Y, Zhang X, Dai C, Liu D
Frontiers in oncology 2021;11:695740
Frontiers in oncology 2021;11:695740
MiR-1236-3p Inhibits the Proliferation, Invasion, and Migration of Colon Cancer Cells and Hinders Epithelial-Mesenchymal Transition by Targeting DCLK3.
Zhao Y, Zhou H, Shen J, Yang S, Deng K, Li Q, Cui W
Frontiers in oncology 2021;11:688882
Frontiers in oncology 2021;11:688882
PGK1 Is a Key Target for Anti-Glycolytic Therapy of Ovarian Cancer: Based on the Comprehensive Analysis of Glycolysis-Related Genes.
Gou R, Hu Y, Liu O, Dong H, Gao L, Wang S, Zheng M, Li X, Lin B
Frontiers in oncology 2021;11:682461
Frontiers in oncology 2021;11:682461
miR-1258 Attenuates Tumorigenesis Through Targeting E2F1 to Inhibit PCNA and MMP2 Transcription in Glioblastoma.
Qin H, Gui Y, Ma R, Zhang H, Guo Y, Ye Y, Li J, Zhao L, Wang Y
Frontiers in oncology 2021;11:671144
Frontiers in oncology 2021;11:671144
N2E4, a Monoclonal Antibody Targeting Neuropilin-2, Inhibits Tumor Growth and Metastasis in Pancreatic Ductal Adenocarcinoma via Suppressing FAK/Erk/HIF-1α Signaling.
Wang L, Wang L, Wang S, Zhou Z, Liu Z, Xu P, Luo X, Wu T, Luo F, Yan J
Frontiers in oncology 2021;11:657008
Frontiers in oncology 2021;11:657008
The lncRNA ADAMTS9-AS2 Regulates RPL22 to Modulate TNBC Progression via Controlling the TGF-β Signaling Pathway.
Ni K, Huang Z, Zhu Y, Xue D, Jin Q, Zhang C, Gu C
Frontiers in oncology 2021;11:654472
Frontiers in oncology 2021;11:654472
Long Non-Coding RNA LINC00467 Correlates to Poor Prognosis and Aggressiveness of Breast Cancer.
Zhang Y, Sun Y, Ding L, Shi W, Ding K, Zhu Y
Frontiers in oncology 2021;11:643394
Frontiers in oncology 2021;11:643394
Derivation and Validation of a Prognostic Model for Cancer Dependency Genes Based on CRISPR-Cas9 in Gastric Adenocarcinoma.
Zhou W, Li J, Lu X, Liu F, An T, Xiao X, Kuo ZC, Wu W, He Y
Frontiers in oncology 2021;11:617289
Frontiers in oncology 2021;11:617289
miR-139-5p Loss-Mediated WTAP Activation Contributes to Hepatocellular Carcinoma Progression by Promoting the Epithelial to Mesenchymal Transition.
Liu W, Gao X, Chen X, Zhao N, Sun Y, Zou Y, Guan Y, Yang L, Pei X, Wang G, Wang B, Li M, Song W
Frontiers in oncology 2021;11:611544
Frontiers in oncology 2021;11:611544
Association of Preoperative NANOG-Positive Circulating Tumor Cell Levels With Recurrence of Hepatocellular Carcinoma.
Lei Y, Wang X, Sun H, Fu Y, Tian Y, Yang L, Wang J, Xia F
Frontiers in oncology 2021;11:601668
Frontiers in oncology 2021;11:601668
Epigallocatechin-3-gallate inhibits proliferation and triggers apoptosis in colon cancer via the hedgehog/phosphoinositide 3-kinase pathways.
Ding F, Yang S
Canadian journal of physiology and pharmacology 2021 Sep;99(9):910-920
Canadian journal of physiology and pharmacology 2021 Sep;99(9):910-920
Aiduqing formula suppresses breast cancer metastasis via inhibiting CXCL1-mediated autophagy.
Yang B, Peng F, Zhang Y, Wang X, Wang S, Zheng Y, Zhang J, Zeng Y, Wang N, Peng C, Wang Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Sep;90:153628
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Sep;90:153628
Homoharringtonine inhibits the progression of hepatocellular carcinoma by suppressing the PI3K/AKT/GSK3β/Slug signaling pathway.
Liu HY, Dong TX, Li ZZ, Li TT, Jiang J, Zhu MW, An TT, Chen YD, Yang XH
Neoplasma 2021 Sep;68(5):924-937
Neoplasma 2021 Sep;68(5):924-937
Polystyrene microplastics induce blood-testis barrier disruption regulated by the MAPK-Nrf2 signaling pathway in rats.
Li S, Wang Q, Yu H, Yang L, Sun Y, Xu N, Wang N, Lei Z, Hou J, Jin Y, Zhang H, Li L, Xu F, Zhang L
Environmental science and pollution research international 2021 Sep;28(35):47921-47931
Environmental science and pollution research international 2021 Sep;28(35):47921-47931
Demethylzeylasteral inhibits proliferation, migration, and invasion through FBXW7/c-Myc axis in gastric cancer.
Li Y, Su Y, Zhao Y, Hu X, Zhao G, He J, Wan S, Lü M, Cui H
MedComm 2021 Sep;2(3):467-480
MedComm 2021 Sep;2(3):467-480
Investigation of the Epithelial to Mesenchymal Transition (EMT) Process in Equine Papillomavirus-2 (EcPV-2)-Positive Penile Squamous Cell Carcinomas.
Armando F, Mecocci S, Orlandi V, Porcellato I, Cappelli K, Mechelli L, Brachelente C, Pepe M, Gialletti R, Ghelardi A, Passeri B, Razzuoli E
International journal of molecular sciences 2021 Sep 30;22(19)
International journal of molecular sciences 2021 Sep 30;22(19)
Identification of abnormally high expression of POGZ as a new biomarker associated with a poor prognosis in osteosarcoma.
Zheng S, Liu Y, Sun H, Jia J, Wu T, Ding R, Cheng X
European journal of histochemistry : EJH 2021 Sep 3;65(3)
European journal of histochemistry : EJH 2021 Sep 3;65(3)
PHLDA3 exerts an antitumor function in prostate cancer by down-regulating Wnt/β-catenin pathway via inhibition of Akt.
Ma S, Quan P, Yu C, Fan X, Yang S, Jia W, Zhang L, Wang F, Liu F, Yang L, Qin W, Yang X
Biochemical and biophysical research communications 2021 Sep 24;571:66-73
Biochemical and biophysical research communications 2021 Sep 24;571:66-73
KLK8 promotes the proliferation and metastasis of colorectal cancer via the activation of EMT associated with PAR1.
Hua Q, Sun Z, Liu Y, Shen X, Zhao W, Zhu X, Xu P
Cell death & disease 2021 Sep 22;12(10):860
Cell death & disease 2021 Sep 22;12(10):860
MiR-613 inhibits the proliferation, migration, and invasion of papillary thyroid carcinoma cells by directly targeting TAGLN2.
Huang Y, Zhang H, Wang L, Liu C, Guo M, Tan H, Liu Z
Cancer cell international 2021 Sep 16;21(1):494
Cancer cell international 2021 Sep 16;21(1):494
TNFSF9 promotes metastasis of pancreatic cancer through Wnt/Snail signaling and M2 polarization of macrophages.
Wu J, Wang Y, Yang Y, Liu F, Chen J, Jiang Z, Jiang Z
Aging 2021 Sep 13;13(17):21571-21586
Aging 2021 Sep 13;13(17):21571-21586
Oleanolic acid inhibits the migration and invasion of hepatocellular carcinoma cells by promoting microRNA-122 expression.
He Y, Liu X, Huang M, Wei Z, Zhang M, He M, Zheng Z, Dong H, Liu D
Die Pharmazie 2021 Sep 1;76(9):422-427
Die Pharmazie 2021 Sep 1;76(9):422-427
MIER3 induces epithelial-mesenchymal transition and promotes breast cancer cell aggressiveness via forming a co-repressor complex with HDAC1/HDAC2/Snail.
Huang W, Chen J, Liu X, Liu X, Duan S, Chen L, Liu X, Lan J, Zou Y, Guo D, Zhou J
Experimental cell research 2021 Sep 1;406(1):112722
Experimental cell research 2021 Sep 1;406(1):112722
Upregulation of microfibrillar-associated protein 2 is closely associated with tumor angiogenesis and poor prognosis in hepatocellular carcinoma.
Zhang N, Shao F, Jia W
Oncology letters 2021 Oct;22(4):739
Oncology letters 2021 Oct;22(4):739
Dihydroartemisinin suppresses proliferation, migration, the Wnt/β-catenin pathway and EMT via TNKS in gastric cancer.
Ma Y, Zhang P, Zhang Q, Wang X, Miao Q, Lyu X, Cui B, Ma H
Oncology letters 2021 Oct;22(4):688
Oncology letters 2021 Oct;22(4):688
PFP@PLGA/Cu(12)Sb(4)S(13)-mediated PTT ablates hepatocellular carcinoma by inhibiting the RAS/MAPK/MT-CO1 signaling pathway.
Dong T, Jiang J, Zhang H, Liu H, Zou X, Niu J, Mao Y, Zhu M, Chen X, Li Z, Chen Y, Shi C, Yang X
Nano convergence 2021 Oct 4;8(1):29
Nano convergence 2021 Oct 4;8(1):29
AnnexinA7 promotes epithelial-mesenchymal transition by interacting with Sorcin and contributes to aggressiveness in hepatocellular carcinoma.
Ling F, Zhang H, Sun Y, Meng J, Sanches JGP, Huang H, Zhang Q, Yu X, Wang B, Hou L, Zhang J
Cell death & disease 2021 Oct 29;12(11):1018
Cell death & disease 2021 Oct 29;12(11):1018
UM-6 induces autophagy and apoptosis via the Hippo-YAP signaling pathway in cervical cancer.
Wang D, He J, Dong J, Wu S, Liu S, Zhu H, Xu T
Cancer letters 2021 Oct 28;519:2-19
Cancer letters 2021 Oct 28;519:2-19
ZEB1 represses biogenesis of circ-DOCK5 to facilitate metastasis in esophageal squamous cell carcinoma via a positive feedback loop with TGF-β.
Meng L, Zheng Y, Liu S, Ju Y, Ren S, Sang Y, Zhu Y, Gu L, Liu F, Zhao Y, Zhang X, Sang M
Cancer letters 2021 Oct 28;519:117-129
Cancer letters 2021 Oct 28;519:117-129
Circular RNA circUBE2J2 acts as the sponge of microRNA-370-5P to suppress hepatocellular carcinoma progression.
Zhang L, Liu Y, Tao H, Zhu H, Pan Y, Li P, Liang H, Zhang B, Song J
Cell death & disease 2021 Oct 22;12(11):985
Cell death & disease 2021 Oct 22;12(11):985
NOV/CCN3 Promotes Cell Migration and Invasion in Intrahepatic Cholangiocarcinoma via miR-92a-3p.
Liang T, Shen L, Ji Y, Jia L, Dou Y, Guo L
Genes 2021 Oct 21;12(11)
Genes 2021 Oct 21;12(11)
RTA404, an Activator of Nrf2, Activates the Checkpoint Kinases and Induces Apoptosis through Intrinsic Apoptotic Pathway in Malignant Glioma.
Tsai TH, Lieu AS, Huang TY, Kwan AL, Lin CL, Hsu YC
Journal of clinical medicine 2021 Oct 20;10(21)
Journal of clinical medicine 2021 Oct 20;10(21)
Upregulation of CPNE7 in mesenchymal stromal cells promotes oral squamous cell carcinoma metastasis through the NF-κB pathway.
Ji X, Sun T, Xie S, Qian H, Song L, Wang L, Liu H, Feng Q
Cell death discovery 2021 Oct 14;7(1):294
Cell death discovery 2021 Oct 14;7(1):294
GP73-mediated secretion of AFP and GP73 promotes proliferation and metastasis of hepatocellular carcinoma cells.
Liu Y, Wang J, Yang R, Cheng Y, Zhou Y, Li H, Jiang W, Zhang X
Oncogenesis 2021 Oct 14;10(10):69
Oncogenesis 2021 Oct 14;10(10):69
P-element Induced WImpy protein-like RNA-mediated gene silencing 2 regulates tumor cell progression, apoptosis, and metastasis in oral squamous cell carcinoma.
Zhou S, Yang S, Li F, Hou J, Chang H
The Journal of international medical research 2021 Nov;49(11):3000605211053158
The Journal of international medical research 2021 Nov;49(11):3000605211053158
Abnormally elevated ubiquilin‑1 expression in breast cancer regulates metastasis and stemness via AKT signaling.
Feng X, Cao A, Qin T, Zhang Q, Fan S, Wang B, Song B, Yu X, Li L
Oncology reports 2021 Nov;46(5)
Oncology reports 2021 Nov;46(5)
Silencing ACTG1 Expression Induces Prostate Cancer Epithelial Mesenchymal Transition Through MAPK/ERK Signaling Pathway.
Xiao L, Peng H, Yan M, Chen S
DNA and cell biology 2021 Nov;40(11):1445-1455
DNA and cell biology 2021 Nov;40(11):1445-1455
The anti-neoplastic activities of aloperine in HeLa cervical cancer cells are associated with inhibition of the IL-6-JAK1-STAT3 feedback loop.
Chen YD, Cai FY, Mao YZ, Yang YS, Xu K, Liu XF, Fan WW, Chen W, Jiang FQ, Zhang H
Chinese journal of natural medicines 2021 Nov;19(11):815-824
Chinese journal of natural medicines 2021 Nov;19(11):815-824
Effects of Cynaroside on Cell Proliferation, Apoptosis, Migration and Invasion though the MET/AKT/mTOR Axis in Gastric Cancer.
Ji J, Wang Z, Sun W, Li Z, Cai H, Zhao E, Cui H
International journal of molecular sciences 2021 Nov 9;22(22)
International journal of molecular sciences 2021 Nov 9;22(22)
WITHDRAWN: Transcriptional regulation of miR-483-3p mediated by IL-6/STAT3 axis promoted epithelial-mesenchymal transition and tumor stemness in glioma.
Xu D, Chi G, Xu D
Aging 2021 Nov 8;12
Aging 2021 Nov 8;12
HMMR is a downstream target of FOXM1 in enhancing proliferation and partial epithelial-to-mesenchymal transition of bladder cancer cells.
Yang D, Ma Y, Zhao P, Ma J, He C
Experimental cell research 2021 Nov 15;408(2):112860
Experimental cell research 2021 Nov 15;408(2):112860
Drug-containing serum of rhubarb-astragalus capsule inhibits the epithelial-mesenchymal transformation of HK-2 by downregulating TGF-β1/p38MAPK/Smad2/3 pathway.
Qin MY, Huang SQ, Zou XQ, Zhong XB, Yang YF, Zhang YT, Mi ZC, Zhang YS, Huang ZG
Journal of ethnopharmacology 2021 Nov 15;280:114414
Journal of ethnopharmacology 2021 Nov 15;280:114414
Single-Cell Analyses Reveal Mechanisms of Cancer Stem Cell Maintenance and Epithelial-Mesenchymal Transition in Recurrent Bladder Cancer.
Wang H, Mei Y, Luo C, Huang Q, Wang Z, Lu GM, Qin L, Sun Z, Huang CW, Yang ZW, Chen J, Yin W, Qian CN, Zeng J, Chen L, Leng Q, Guo Y, Jia G
Clinical cancer research : an official journal of the American Association for Cancer Research 2021 Nov 15;27(22):6265-6278
Clinical cancer research : an official journal of the American Association for Cancer Research 2021 Nov 15;27(22):6265-6278
Deletion of miR-15a inhibited glioma development via targeting Smad7 and inhibiting EMT pathway.
Guo Y, Gao X, An S, Li X, Pan L, Liu H, Liu J, Gao J, Zhao Z, Li G, Han Y, Li Y, Ji Z
Aging 2021 Nov 11;13(21):24339-24348
Aging 2021 Nov 11;13(21):24339-24348
Methylation gene KCNC1 is associated with overall survival in patients with seminoma.
Chen S, Xiao L, Peng H, Wang Z, Xie J
Oncology reports 2021 May;45(5)
Oncology reports 2021 May;45(5)
The clinical significance, prognostic value and biological role of lncRNA LINC01793 in oral squamous cell carcinoma.
Yuan SJ, Li SY, Wang YH, Zhang HF, Hua Y, Wang T
Archives of oral biology 2021 May;125:105105
Archives of oral biology 2021 May;125:105105
Ginsenoside CK Inhibits Hypoxia-Induced Epithelial-Mesenchymal Transformation through the HIF-1α/NF-κB Feedback Pathway in Hepatocellular Carcinoma.
Zhang J, Ma X, Fan D
Foods (Basel, Switzerland) 2021 May 26;10(6)
Foods (Basel, Switzerland) 2021 May 26;10(6)
Identification of collagen genes related to immune infiltration and epithelial-mesenchymal transition in glioma.
Yin W, Zhu H, Tan J, Xin Z, Zhou Q, Cao Y, Wu Z, Wang L, Zhao M, Jiang X, Ren C, Tang G
Cancer cell international 2021 May 25;21(1):276
Cancer cell international 2021 May 25;21(1):276
Knockout RAGE alleviates cardiac fibrosis through repressing endothelial-to-mesenchymal transition (EndMT) mediated by autophagy.
Zhang L, He J, Wang J, Liu J, Chen Z, Deng B, Wei L, Wu H, Liang B, Li H, Huang Y, Lu L, Yang Z, Xian S, Wang L
Cell death & disease 2021 May 11;12(5):470
Cell death & disease 2021 May 11;12(5):470
Hsa_circ_0076305 induces migration-proliferation dichotomy in gastric cancer.
Zhang Y, Hong Y, Wang D, Duan L, Liu Y, Li L, Liu D, Zhuang K, Wei C, Zheng G, Huo C, Liu G
Oncology letters 2021 Mar;21(3):220
Oncology letters 2021 Mar;21(3):220
Aptamer-SH2 superbinder-based targeted therapy for pancreatic ductal adenocarcinoma.
Liu AD, Zhou J, Bi XY, Hou GQ, Li SS, Chen Q, Xu H, Cao X
Clinical and translational medicine 2021 Mar;11(3):e337
Clinical and translational medicine 2021 Mar;11(3):e337
Structural basis for human TRPC5 channel inhibition by two distinct inhibitors.
Song K, Wei M, Guo W, Quan L, Kang Y, Wu JX, Chen L
eLife 2021 Mar 8;10
eLife 2021 Mar 8;10
Sesquiterpene Lactone Deoxyelephantopin Isolated from Elephantopus scaber and Its Derivative DETD-35 Suppress BRAF(V600E) Mutant Melanoma Lung Metastasis in Mice.
Cvetanova B, Li MY, Yang CC, Hsiao PW, Yang YC, Feng JH, Shen YC, Nakagawa-Goto K, Lee KH, Shyur LF
International journal of molecular sciences 2021 Mar 22;22(6)
International journal of molecular sciences 2021 Mar 22;22(6)
DCBLD2 Mediates Epithelial-Mesenchymal Transition-Induced Metastasis by Cisplatin in Lung Adenocarcinoma.
Chen X, Lv Y, Xu K, Wang X, Zhao Y, Li J, Qin X, Shi Y, Wang L, Chang A, Huang C, Xiang R
Cancers 2021 Mar 19;13(6)
Cancers 2021 Mar 19;13(6)
PEG-GO@XN nanocomposite suppresses breast cancer metastasis via inhibition of mitochondrial oxidative phosphorylation and blockade of epithelial-to-mesenchymal transition.
Zhang J, Yan L, Wei P, Zhou R, Hua C, Xiao M, Tu Y, Gu Z, Wei T
European journal of pharmacology 2021 Mar 15;895:173866
European journal of pharmacology 2021 Mar 15;895:173866
Upregulation of bromodomain PHD finger transcription factor in ovarian cancer and its critical role for cancer cell proliferation and survival.
Miao J, Zhang M, Huang X, Xu L, Tang R, Wang H, Han S
Biochemistry and cell biology = Biochimie et biologie cellulaire 2021 Jun;99(3):304-312
Biochemistry and cell biology = Biochimie et biologie cellulaire 2021 Jun;99(3):304-312
Suberoylanilide Hydroxamic Acid (SAHA) Reduces Fibrosis Markers and Deactivates Human Stellate Cells via the Epithelial-Mesenchymal Transition (EMT).
Özel M, Baskol M, Akalın H, Baskol G
Cell biochemistry and biophysics 2021 Jun;79(2):349-357
Cell biochemistry and biophysics 2021 Jun;79(2):349-357
MicroRNA‑485‑5p suppresses the progression of esophageal squamous cell carcinoma by targeting flotillin‑1 and inhibits the epithelial‑mesenchymal transition.
Zhao R, Shan Y, Zhou X, Zhang C, Zhao R, Zhao L, Shan B
Oncology reports 2021 Jun;45(6)
Oncology reports 2021 Jun;45(6)
Fructose-1,6-bisphosphatase aggravates oxidative stress-induced apoptosis in asthma by suppressing the Nrf2 pathway.
Hu J, Wang J, Li C, Shang Y
Journal of cellular and molecular medicine 2021 Jun;25(11):5001-5014
Journal of cellular and molecular medicine 2021 Jun;25(11):5001-5014
SEC61G is upregulated and required for tumor progression in human kidney cancer.
Meng H, Jiang X, Wang J, Sang Z, Guo L, Yin G, Wang Y
Molecular medicine reports 2021 Jun;23(6)
Molecular medicine reports 2021 Jun;23(6)
MicroRNA-133a-3p suppresses malignant behavior of non-small cell lung cancer cells by negatively regulating ERBB2.
Xu Y, Zhang L, Xia L, Zhu X
Oncology letters 2021 Jun;21(6):457
Oncology letters 2021 Jun;21(6):457
LEM domain containing 1 promotes thyroid cancer cell proliferation and migration by activating the Wnt/β-catenin signaling pathway and epithelial-mesenchymal transition.
Xu M, Lin B, Zheng D, Wen J, Hu W, Li C, Zhang X, Zhang X, Qu J
Oncology letters 2021 Jun;21(6):442
Oncology letters 2021 Jun;21(6):442
Ketoplatin in triple-negative breast cancer cells MDA-MB-231: High efficacy and low toxicity, and positive impact on inflammatory microenvironment.
Ma ZY, Song XQ, Hu JJ, Wang DB, Ding XJ, Liu RP, Dai ML, Meng FY, Xu JY
Biochemical pharmacology 2021 Jun;188:114523
Biochemical pharmacology 2021 Jun;188:114523
LncRNA MONC suppresses the malignant phenotype of Endometrial Cancer Stem Cells and Endometrial Carcinoma Cells by regulating the MiR-636/GLCE axis.
Li Y, Huo J, He J, Ma X
Cancer cell international 2021 Jun 30;21(1):331
Cancer cell international 2021 Jun 30;21(1):331
CD74 promotes perineural invasion of cancer cells and mediates neuroplasticity via the AKT/EGR-1/GDNF axis in pancreatic ductal adenocarcinoma.
Zhang JF, Tao LY, Yang MW, Xu DP, Jiang SH, Fu XL, Liu DJ, Huo YM, Liu W, Yang JY, Hua R, Lu P, Sun YW
Cancer letters 2021 Jun 28;508:47-58
Cancer letters 2021 Jun 28;508:47-58
Identification of a Novel TAR RNA-Binding Protein 2 Modulator with Potential Therapeutic Activity against Hepatocellular Carcinoma.
Zhou Z, Li Y, Ma X, Cao B, Peng T, Sheng Y, Peng H, Li R, Cao Y, Xi R, Li F, Wang M, Sun H, Zhang G, Zhang H, Hu K, Xiao W, Wang F
Journal of medicinal chemistry 2021 Jun 10;64(11):7404-7421
Journal of medicinal chemistry 2021 Jun 10;64(11):7404-7421
YB1 regulates miR-205/200b-ZEB1 axis by inhibiting microRNA maturation in hepatocellular carcinoma.
Liu X, Chen D, Chen H, Wang W, Liu Y, Wang Y, Duan C, Ning Z, Guo X, Otkur W, Liu J, Qi H, Liu X, Lin A, Xia T, Liu HX, Piao HL
Cancer communications (London, England) 2021 Jul;41(7):576-595
Cancer communications (London, England) 2021 Jul;41(7):576-595
Regulatory effect of microRNA-223-3p on breast cancer cell processes via the Hippo/Yap signaling pathway.
Du T, Wang D, Wan X, Xu J, Xiao Q, Liu B
Oncology letters 2021 Jul;22(1):516
Oncology letters 2021 Jul;22(1):516
The oncogenic role of the cerebral endothelial cell adhesion molecule (CERCAM) in bladder cancer cells in vitro and in vivo.
Zuo Y, Xu X, Chen M, Qi L
Cancer medicine 2021 Jul;10(13):4437-4450
Cancer medicine 2021 Jul;10(13):4437-4450
A novel chemical inhibitor suppresses breast cancer cell growth and metastasis through inhibiting HPIP oncoprotein.
Li P, Cao S, Huang Y, Zhang Y, Liu J, Cai X, Zhou L, Li J, Jiang Z, Ding L, Zheng Z, Li S, Ye Q
Cell death discovery 2021 Jul 29;7(1):198
Cell death discovery 2021 Jul 29;7(1):198
TGF-β1-mediated exosomal lnc-MMP2-2 increases blood-brain barrier permeability via the miRNA-1207-5p/EPB41L5 axis to promote non-small cell lung cancer brain metastasis.
Wu D, Deng S, Li L, Liu T, Zhang T, Li J, Yu Y, Xu Y
Cell death & disease 2021 Jul 20;12(8):721
Cell death & disease 2021 Jul 20;12(8):721
METTL7B is a novel prognostic biomarker of lower-grade glioma based on pan-cancer analysis.
Jiang Z, Yin W, Zhu H, Tan J, Guo Y, Xin Z, Zhou Q, Cao Y, Wu Z, Kuang Y, Li C, Xie D, Huang H, Zhao M, Jiang X, Wang L, Ren C
Cancer cell international 2021 Jul 19;21(1):383
Cancer cell international 2021 Jul 19;21(1):383
Circular RNA circ_001422 promotes the progression and metastasis of osteosarcoma via the miR-195-5p/FGF2/PI3K/Akt axis.
Yang B, Li L, Tong G, Zeng Z, Tan J, Su Z, Liu Z, Lin J, Gao W, Chen J, Zeng S, Wu G, Li L, Zhu S, Liu Q, Lin L
Journal of experimental & clinical cancer research : CR 2021 Jul 16;40(1):235
Journal of experimental & clinical cancer research : CR 2021 Jul 16;40(1):235
LncRNA PCGEM1 induces proliferation and migration in non-small cell lung cancer cells through modulating the miR-590-3p/SOX11 axis.
Wen H, Feng H, Ma Q, Liang C
BMC pulmonary medicine 2021 Jul 14;21(1):234
BMC pulmonary medicine 2021 Jul 14;21(1):234
Mitochondrial creatine kinase 1 in non-small cell lung cancer progression and hypoxia adaptation.
Li M, Liu H, Li J, Guo S, Lv Y
Respiratory research 2021 Jul 1;22(1):190
Respiratory research 2021 Jul 1;22(1):190
Fangchinoline exerts antitumour activity by suppressing the EGFR‑PI3K/AKT signalling pathway in colon adenocarcinoma.
Jiang F, Ren S, Chen Y, Zhang A, Zhu Y, Zhang Z, Li Z, Piao D
Oncology reports 2021 Jan;45(1):139-150
Oncology reports 2021 Jan;45(1):139-150
MSH6 Aggravates the Hypoxic Microenvironment via Regulating HIF1A to Promote the Metastasis of Glioblastoma Multiforme.
Shi Y, Jiang J, Cui Y, Chen Y, Dong T, An H, Liu P
DNA and cell biology 2021 Jan;40(1):93-100
DNA and cell biology 2021 Jan;40(1):93-100
Triptolidenol, isolated from Tripterygium wilfordii, disrupted NF-κB/COX-2 pathway by targeting ATP-binding sites of IKKβ in clear cell renal cell carcinoma.
Jin J, Zhou M, Wang X, Liu M, Huang H, Yan F, Yu Z, Shu X, Huo X, Feng L, Zhang B, Huang S, Deng S, Wang C, Ma X
Fitoterapia 2021 Jan;148:104779
Fitoterapia 2021 Jan;148:104779
Lidocaine inhibits the metastatic potential of ovarian cancer by blocking Na(V) 1.5-mediated EMT and FAK/Paxillin signaling pathway.
Liu C, Yu M, Li Y, Wang H, Xu C, Zhang X, Li M, Guo H, Ma D, Guo X
Cancer medicine 2021 Jan;10(1):337-349
Cancer medicine 2021 Jan;10(1):337-349
Glycosyltransferase POMGNT1 deficiency strengthens N-cadherin-mediated cell-cell adhesion.
Noor SI, Hoffmann M, Rinis N, Bartels MF, Winterhalter PR, Hoelscher C, Hennig R, Himmelreich N, Thiel C, Ruppert T, Rapp E, Strahl S
The Journal of biological chemistry 2021 Jan-Jun;296:100433
The Journal of biological chemistry 2021 Jan-Jun;296:100433
Obacunone Attenuates Liver Fibrosis with Enhancing Anti-Oxidant Effects of GPx-4 and Inhibition of EMT.
Bai Y, Wang W, Wang L, Ma L, Zhai D, Wang F, Shi R, Liu C, Xu Q, Chen G, Lu Z
Molecules (Basel, Switzerland) 2021 Jan 9;26(2)
Molecules (Basel, Switzerland) 2021 Jan 9;26(2)
Polystyrene microplastics induced male reproductive toxicity in mice.
Jin H, Ma T, Sha X, Liu Z, Zhou Y, Meng X, Chen Y, Han X, Ding J
Journal of hazardous materials 2021 Jan 5;401:123430
Journal of hazardous materials 2021 Jan 5;401:123430
Histone methyltransferase SUV39H2 regulates LSD1-dependent CDH1 expression and promotes epithelial mesenchymal transition of osteosarcoma.
Miao Y, Liu G, Liu L
Cancer cell international 2021 Jan 4;21(1):2
Cancer cell international 2021 Jan 4;21(1):2
Overexpression of NCAPG inhibits cardia adenocarcinoma apoptosis and promotes epithelial-mesenchymal transition through the Wnt/β-catenin signaling pathway.
Zhang X, Zhu M, Wang H, Song Z, Zhan D, Cao W, Han Y, Jia J
Gene 2021 Jan 15;766:145163
Gene 2021 Jan 15;766:145163
Circ_0001438 participates in the pathogenesis of preeclampsia via the circ_0001438/miR-942/NLRP3 regulatory network.
Li X, Yang R, Xu Y, Zhang Y
Placenta 2021 Jan 15;104:40-50
Placenta 2021 Jan 15;104:40-50
A "dual-guide" bioinspired drug delivery strategy of a macrophage-based carrier against postoperative triple-negative breast cancer recurrence.
Qiu Y, Ren K, Zhao W, Yu Q, Guo R, He J, Mei L, Liu Y, Tang J, Xu S, Li J, Wei J, Li M, Zhang Z, He Q
Journal of controlled release : official journal of the Controlled Release Society 2021 Jan 10;329:191-204
Journal of controlled release : official journal of the Controlled Release Society 2021 Jan 10;329:191-204
PGRN(-/-) TAMs-derived exosomes inhibit breast cancer cell invasion and migration and its mechanism exploration.
Yue S, Ye X, Zhou T, Gan D, Qian H, Fang W, Yao M, Zhang D, Shi H, Chen T
Life sciences 2021 Jan 1;264:118687
Life sciences 2021 Jan 1;264:118687
Prostacyclin facilitates vascular smooth muscle cell phenotypic transformation via activating TP receptors when IP receptors are deficient.
Li Z, Luo W, Fang S, Chen X, Lin T, Zhou S, Zhang L, Yang W, Li Z, Ye J, Wang J, Liu P, Li Z
Acta physiologica (Oxford, England) 2021 Feb;231(2):e13555
Acta physiologica (Oxford, England) 2021 Feb;231(2):e13555
USP1-WDR48 deubiquitinase complex enhances TGF-β induced epithelial-mesenchymal transition of TNBC cells via stabilizing TAK1.
Han D, Wang L, Chen B, Zhao W, Liang Y, Li Y, Zhang H, Liu Y, Wang X, Chen T, Li C, Song X, Luo D, Li Z, Yang Q
Cell cycle (Georgetown, Tex.) 2021 Feb;20(3):320-331
Cell cycle (Georgetown, Tex.) 2021 Feb;20(3):320-331
Cancer-associated fibroblast-derived SDF-1 induces epithelial-mesenchymal transition of lung adenocarcinoma via CXCR4/β-catenin/PPARδ signalling.
Wang Y, Lan W, Xu M, Song J, Mao J, Li C, Du X, Jiang Y, Li E, Zhang R, Wang Q
Cell death & disease 2021 Feb 26;12(2):214
Cell death & disease 2021 Feb 26;12(2):214
DUOX2 promotes the progression of colorectal cancer cells by regulating the AKT pathway and interacting with RPL3.
Zhang X, Han J, Feng L, Zhi L, Jiang D, Yu B, Zhang Z, Gao B, Zhang C, Li M, Zhao L, Wang G
Carcinogenesis 2021 Feb 11;42(1):105-117
Carcinogenesis 2021 Feb 11;42(1):105-117
Long non-coding RNA AC122108.1 promotes lung adenocarcinoma brain metastasis and progression through the Wnt/β-catenin pathway by directly binding to aldolase A.
Feng S, Liu H, Du P, Dong X, Pang Q, Guo H
Annals of translational medicine 2021 Dec;9(23):1729
Annals of translational medicine 2021 Dec;9(23):1729
PDGF-BB promotes vascular smooth muscle cell migration by enhancing Pim-1 expression via inhibiting miR-214.
Zhou J, Shao L, Yu J, Huang J, Feng Q
Annals of translational medicine 2021 Dec;9(23):1728
Annals of translational medicine 2021 Dec;9(23):1728
IFIT1 modulates the proliferation, migration and invasion of pancreatic cancer cells via Wnt/β-catenin signaling.
Li TH, Zhao BB, Qin C, Wang YY, Li ZR, Cao HT, Yang XY, Zhou XT, Wang WB
Cellular oncology (Dordrecht, Netherlands) 2021 Dec;44(6):1425-1437
Cellular oncology (Dordrecht, Netherlands) 2021 Dec;44(6):1425-1437
Exosomal ANXA2 derived from ovarian cancer cells regulates epithelial-mesenchymal plasticity of human peritoneal mesothelial cells.
Gao L, Nie X, Gou R, Hu Y, Dong H, Li X, Lin B
Journal of cellular and molecular medicine 2021 Dec;25(23):10916-10929
Journal of cellular and molecular medicine 2021 Dec;25(23):10916-10929
Knockdown of METTL14 suppresses the malignant progression of non-small cell lung cancer by reducing Twist expression.
Yang F, Yuan WQ, Li J, Luo YQ
Oncology letters 2021 Dec;22(6):847
Oncology letters 2021 Dec;22(6):847
TRIP4 transcriptionally activates DDIT4 and subsequent mTOR signaling to promote glioma progression.
Li W, Hu S, Tian C, Wan X, Yu W, Guo P, Zhao F, Hua C, Lu X, Xue G, Han S, Guo W, Wang D, Deng W
Free radical biology & medicine 2021 Dec;177:31-47
Free radical biology & medicine 2021 Dec;177:31-47
Long non-coding RNA VCAN-AS1 promotes the malignant behaviors of breast cancer by regulating the miR-106a-5p-mediated STAT3/HIF-1α pathway.
Du P, Luo K, Li G, Zhu J, Xiao Q, Li Y, Zhang X
Bioengineered 2021 Dec;12(1):5028-5044
Bioengineered 2021 Dec;12(1):5028-5044
Knockdown of carbohydrate sulfotransferase 12 decreases the proliferation and mobility of glioblastoma cells via the WNT/β-catenin pathway.
Wang J, Xia X, Tao X, Zhao P, Deng C
Bioengineered 2021 Dec;12(1):3934-3946
Bioengineered 2021 Dec;12(1):3934-3946
SETD8 induces stemness and epithelial-mesenchymal transition of pancreatic cancer cells by regulating ROR1 expression.
Liu M, Shi Y, Hu Q, Qin Y, Ji S, Liu W, Zhuo Q, Fan G, Ye Z, Song C, Yu X, Xu X, Xu W
Acta biochimica et biophysica Sinica 2021 Dec 8;53(12):1614-1624
Acta biochimica et biophysica Sinica 2021 Dec 8;53(12):1614-1624
Long non-coding RNA CRNDE exacerbates NPC advancement mediated by the miR-545-5p/CCND2 axis.
Ge S, Jiang C, Li M, Cheng Z, Feng X
Cancer cell international 2021 Dec 4;21(1):650
Cancer cell international 2021 Dec 4;21(1):650
Cancer-Erythrocyte Hybrid Membrane-Camouflaged Magnetic Nanoparticles with Enhanced Photothermal-Immunotherapy for Ovarian Cancer.
Xiong J, Wu M, Chen J, Liu Y, Chen Y, Fan G, Liu Y, Cheng J, Wang Z, Wang S, Liu Y, Zhang W
ACS nano 2021 Dec 28;15(12):19756-19770
ACS nano 2021 Dec 28;15(12):19756-19770
TMED3 exerts a protumor function in non-small cell lung cancer by enhancing the Wnt/β-catenin pathway via regulation of AKT.
Zhang D, Sun L, Zhang J
Toxicology and applied pharmacology 2021 Dec 15;433:115793
Toxicology and applied pharmacology 2021 Dec 15;433:115793
ATF3 inhibits arsenic-induced malignant transformation of human bronchial epithelial cells by attenuating inflammation.
Shi Q, Hu B, Yang C, Deng S, Cheng X, Wu J, Qi N
Toxicology 2021 Aug;460:152890
Toxicology 2021 Aug;460:152890
TMEM229A suppresses non‑small cell lung cancer progression via inactivating the ERK pathway.
Zhang X, He Y, Jiang Y, Bao Y, Chen Q, Xie D, Yu H, Wang X
Oncology reports 2021 Aug;46(2)
Oncology reports 2021 Aug;46(2)
Chromium (VI) promotes EMT by regulating FLNA in BLCA.
Sheng F, Chen KX, Liu J, Li JX, Liang GH, Xu Y, Du E, Zhang ZH
Environmental toxicology 2021 Aug;36(8):1694-1701
Environmental toxicology 2021 Aug;36(8):1694-1701
W436, a novel SMART derivative, exhibits anti-hepatocarcinoma activity by inducing apoptosis and G2/M cell cycle arrest in vitro and in vivo and induces protective autophagy.
Man S, Wu Z, Sun R, Guan Q, Li Z, Zuo D, Zhang W, Wu Y
Journal of biochemical and molecular toxicology 2021 Aug;35(8):e22831
Journal of biochemical and molecular toxicology 2021 Aug;35(8):e22831
Deubiquitinase USP39 and E3 ligase TRIM26 balance the level of ZEB1 ubiquitination and thereby determine the progression of hepatocellular carcinoma.
Li X, Yuan J, Song C, Lei Y, Xu J, Zhang G, Wang W, Song G
Cell death and differentiation 2021 Aug;28(8):2315-2332
Cell death and differentiation 2021 Aug;28(8):2315-2332
miR‑200b upregulation promotes migration of BEAS‑2B cells following long‑term exposure to cigarette smoke by targeting ETS1.
Wang J, Yao R, Luo Q, Tan L, Jia B, Ouyang N, Li Y, Tong J, Li J
Molecular medicine reports 2021 Aug;24(2)
Molecular medicine reports 2021 Aug;24(2)
Tripterygium glycoside suppresses epithelial‑to‑mesenchymal transition of diabetic kidney disease podocytes by targeting autophagy through the mTOR/Twist1 pathway.
Tao M, Zheng D, Liang X, Wu D, Hu K, Jin J, He Q
Molecular medicine reports 2021 Aug;24(2)
Molecular medicine reports 2021 Aug;24(2)
Melatonin inhibits gallbladder cancer cell migration and invasion via ERK-mediated induction of epithelial-to-mesenchymal transition.
Tang H, Shi X, Zhu P, Guo W, Li J, Yan B, Zhang S
Oncology letters 2021 Aug;22(2):609
Oncology letters 2021 Aug;22(2):609
Depletion of CIP2A inhibits the proliferation, migration, invasion and epithelial-mesenchymal transition of glioma cells.
Xu Z, Chen X, Hegazy AM, Zhang S, Liu X, Tian J, Wu J, Shi F, Li L, Niu X, Pu J
Brain research bulletin 2021 Aug;173:14-21
Brain research bulletin 2021 Aug;173:14-21
Caveolin-1 facilitates cell migration by upregulating nuclear receptor 4A2/retinoid X receptor α-mediated β-galactoside α2,6-sialyltransferase I expression in human hepatocarcinoma cells.
Chen X, Wang L, Yu X, Wang S, Zhang J
The international journal of biochemistry & cell biology 2021 Aug;137:106027
The international journal of biochemistry & cell biology 2021 Aug;137:106027
Yak milk-derived exosomes alleviate lipopolysaccharide-induced intestinal inflammation by inhibiting PI3K/AKT/C3 pathway activation.
Gao HN, Hu H, Wen PC, Lian S, Xie XL, Song HL, Yang ZN, Ren FZ
Journal of dairy science 2021 Aug;104(8):8411-8424
Journal of dairy science 2021 Aug;104(8):8411-8424
Association of CASC18/miR-20a-3p/TGFB2 ceRNA axis with occult lymph node metastasis in tongue squamous cell carcinoma.
Zhou B, Zhou Y, Liu Y, Zhang H, Mao H, Peng M, Xu A, Li Z, Wang H, Tan H, Ren H, Zhou X, Long Y
Molecular medicine (Cambridge, Mass.) 2021 Aug 6;27(1):85
Molecular medicine (Cambridge, Mass.) 2021 Aug 6;27(1):85
Cyanidin-3-glucoside suppresses the progression of lung adenocarcinoma by downregulating TP53I3 and inhibiting PI3K/AKT/mTOR pathway.
Chen X, Zhang W, Xu X
World journal of surgical oncology 2021 Aug 6;19(1):232
World journal of surgical oncology 2021 Aug 6;19(1):232
ICAM1 initiates CTC cluster formation and trans-endothelial migration in lung metastasis of breast cancer.
Taftaf R, Liu X, Singh S, Jia Y, Dashzeveg NK, Hoffmann AD, El-Shennawy L, Ramos EK, Adorno-Cruz V, Schuster EJ, Scholten D, Patel D, Zhang Y, Davis AA, Reduzzi C, Cao Y, D'Amico P, Shen Y, Cristofanilli M, Muller WA, Varadan V, Liu H
Nature communications 2021 Aug 11;12(1):4867
Nature communications 2021 Aug 11;12(1):4867
CRSP8 promotes thyroid cancer progression by antagonizing IKKα-induced cell differentiation.
Liao Y, Hua Y, Li Y, Zhang C, Yu W, Guo P, Zou K, Li W, Sun Y, Wang R, Zuo Y, Sui S, Tian C, Hao J, Chen M, Hu S, Chen M, Long Q, Wang X, Zou L, Xie F, Guo W, Deng W
Cell death and differentiation 2021 Apr;28(4):1347-1363
Cell death and differentiation 2021 Apr;28(4):1347-1363
The miR-136-5p/ROCK1 axis suppresses invasion and migration, and enhances cisplatin sensitivity in head and neck cancer cells.
Yang B, Zang J, Yuan W, Jiang X, Zhang F
Experimental and therapeutic medicine 2021 Apr;21(4):317
Experimental and therapeutic medicine 2021 Apr;21(4):317
SPT6 recruits SND1 to co-activate human telomerase reverse transcriptase to promote colon cancer progression.
Diao C, Guo P, Yang W, Sun Y, Liao Y, Yan Y, Zhao A, Cai X, Hao J, Hu S, Yu W, Chen M, Wang R, Li W, Zuo Y, Pan J, Hua C, Lu X, Fan W, Zheng Z, Deng W, Luo G, Guo W
Molecular oncology 2021 Apr;15(4):1180-1202
Molecular oncology 2021 Apr;15(4):1180-1202
H. sinensis mycelium inhibits epithelial-mesenchymal transition by inactivating the midkine pathway in pulmonary fibrosis.
Lu L, Zhu H, Wang H, Liang H, Hou Y, Dou H
Frontiers of medicine 2021 Apr;15(2):313-329
Frontiers of medicine 2021 Apr;15(2):313-329
Loss of CPAP causes sustained EGFR signaling and epithelial-mesenchymal transition in oral cancer.
Gudi RR, Janakiraman H, Howe PH, Palanisamy V, Vasu C
Oncotarget 2021 Apr 13;12(8):807-822
Oncotarget 2021 Apr 13;12(8):807-822
Histone Deacetylases Inhibit the Snail2-Mediated EMT During Metastasis of Hepatocellular Carcinoma Cells.
Hu Y, Nie Q, Dai M, Chen F, Wu H
Frontiers in cell and developmental biology 2020;8:752
Frontiers in cell and developmental biology 2020;8:752
Hypoxia-Inducible Ubiquitin Specific Peptidase 13 Contributes to Tumor Growth and Metastasis via Enhancing the Toll-Like Receptor 4/Myeloid Differentiation Primary Response Gene 88/Nuclear Factor-κB Pathway in Hepatocellular Carcinoma.
Gao S, Chen T, Li L, Liu X, Liu Y, Zhao J, Lu Q, Zeng Z, Xu Q, Huang D, Tu K
Frontiers in cell and developmental biology 2020;8:587389
Frontiers in cell and developmental biology 2020;8:587389
miR-193a-3p Mediates Placenta Accreta Spectrum Development by Targeting EFNB2 via Epithelial-Mesenchymal Transition Pathway Under Decidua Defect Conditions.
Li N, Hou R, Yang T, Liu C, Wei J
Frontiers in molecular biosciences 2020;7:613802
Frontiers in molecular biosciences 2020;7:613802
miR-124-3p Suppresses the Invasiveness and Metastasis of Hepatocarcinoma Cells via Targeting CRKL.
Majid A, Wang J, Nawaz M, Abdul S, Ayesha M, Guo C, Liu Q, Liu S, Sun MZ
Frontiers in molecular biosciences 2020;7:223
Frontiers in molecular biosciences 2020;7:223
PKM2 Promotes Breast Cancer Progression by Regulating Epithelial Mesenchymal Transition.
Xiao H, Zhang L, Chen Y, Zhou C, Wang X, Wang D, Liu Z
Analytical cellular pathology (Amsterdam) 2020;2020:8396023
Analytical cellular pathology (Amsterdam) 2020;2020:8396023
KIF3C Promotes Proliferation, Migration, and Invasion of Glioma Cells by Activating the PI3K/AKT Pathway and Inducing EMT.
Gao Y, Zheng H, Li L, Zhou C, Chen X, Zhou X, Cao Y
BioMed research international 2020;2020:6349312
BioMed research international 2020;2020:6349312
miR-876 Inhibits EMT and Liver Fibrosis via POSTN to Suppress Metastasis in Hepatocellular Carcinoma.
Chen K, Li Z, Zhang M, Wang B, Peng T, Shen Y, Zhang J, Ye J, Liu Y, Tang D, Peng M, Ma D, Xiao Z, Zhang Y, Jin W, Li X
BioMed research international 2020;2020:1964219
BioMed research international 2020;2020:1964219
BTG1 inhibits malignancy as a novel prognosis signature in endometrial carcinoma.
Li Y, Huo J, He J, Zhang Y, Ma X
Cancer cell international 2020;20:490
Cancer cell international 2020;20:490
Down-regulation of TRIB3 inhibits the progression of ovarian cancer via MEK/ERK signaling pathway.
Wang S, Wang C, Li X, Hu Y, Gou R, Guo Q, Nie X, Liu J, Zhu L, Lin B
Cancer cell international 2020;20:418
Cancer cell international 2020;20:418
EphA5 knockdown enhances the invasion and migration ability of esophageal squamous cell carcinoma via epithelial-mesenchymal transition through activating Wnt/β-catenin pathway.
Zhang R, Liu J, Zhang W, Hua L, Qian LT, Zhou SB
Cancer cell international 2020;20:20
Cancer cell international 2020;20:20
HBx mediated Increase of SIRT1 Contributes to HBV-related Hepatocellular Carcinoma Tumorigenesis.
Wang Q, Cheng ST, Chen J
International journal of medical sciences 2020;17(12):1783-1794
International journal of medical sciences 2020;17(12):1783-1794
MFP-FePt-GO Nanocomposites Promote Radiosensitivity of Non-Small Cell Lung Cancer Via Activating Mitochondrial-Mediated Apoptosis and Impairing DNA Damage Repair.
Peng S, Sun Y, Luo Y, Ma S, Sun W, Tang G, Li S, Zhang N, Ren J, Xiao Y, Liu X, Zhang J, Gong Y, Xie C
International journal of biological sciences 2020;16(12):2145-2158
International journal of biological sciences 2020;16(12):2145-2158
Lin28A Regulates Stem-like Properties of Ovarian Cancer Cells by Enriching RAN and HSBP1 mRNA and Up-regulating its Protein Expression.
Zhong Y, Cao L, Ma H, Wang Q, Wei P, Yang J, Mo Y, Cao L, Shuai C, Peng S
International journal of biological sciences 2020;16(11):1941-1953
International journal of biological sciences 2020;16(11):1941-1953
miR-370-3p Alleviates Ulcerative Colitis-Related Colorectal Cancer in Mice Through Inhibiting the Inflammatory Response and Epithelial-Mesenchymal Transition.
Lin L, Wang D, Qu S, Zhao H, Lin Y
Drug design, development and therapy 2020;14:1127-1141
Drug design, development and therapy 2020;14:1127-1141
Cigarette smoke supports stemness and epithelial-mesenchymal transition in bladder cancer stem cells through SHH signaling.
Sun X, Song J, Li E, Geng H, Li Y, Yu D, Zhong C
International journal of clinical and experimental pathology 2020;13(6):1333-1348
International journal of clinical and experimental pathology 2020;13(6):1333-1348
MicroRNA-623 Inhibits Epithelial-Mesenchymal Transition to Attenuate Glioma Proliferation by Targeting TRIM44.
Cui D, Wang K, Liu Y, Gao J, Cui J
OncoTargets and therapy 2020;13:9291-9303
OncoTargets and therapy 2020;13:9291-9303
Characterization of Triple-Negative Breast Cancer MDA-MB-231 Cell Spheroid Model.
Huang Z, Yu P, Tang J
OncoTargets and therapy 2020;13:5395-5405
OncoTargets and therapy 2020;13:5395-5405
Alpha-1 Antitrypsin Induces Epithelial-to-Mesenchymal Transition, Endothelial-to-Mesenchymal Transition, and Drug Resistance in Lung Cancer Cells.
Wu DM, Liu T, Deng SH, Han R, Zhang T, Li J, Xu Y
OncoTargets and therapy 2020;13:3751-3763
OncoTargets and therapy 2020;13:3751-3763
Low-Dose Radiation Promotes Invasion and Migration of A549 Cells by Activating the CXCL1/NF-κB Signaling Pathway.
Li J, Wu DM, Han R, Yu Y, Deng SH, Liu T, Zhang T, Xu Y
OncoTargets and therapy 2020;13:3619-3629
OncoTargets and therapy 2020;13:3619-3629
Fibroblast Activation Protein (FAP) Overexpression Induces Epithelial-Mesenchymal Transition (EMT) in Oral Squamous Cell Carcinoma by Down-Regulating Dipeptidyl Peptidase 9 (DPP9).
Wu QQ, Zhao M, Huang GZ, Zheng ZN, Chen Y, Zeng WS, Lv XZ
OncoTargets and therapy 2020;13:2599-2611
OncoTargets and therapy 2020;13:2599-2611
Tumor Suppressor microRNA-138 Suppresses Low-Grade Glioma Development and Metastasis via Regulating IGF2BP2.
Yang Y, Liu X, Cheng L, Li L, Wei Z, Wang Z, Han G, Wan X, Wang Z, Zhang J, Chen C
OncoTargets and therapy 2020;13:2247-2260
OncoTargets and therapy 2020;13:2247-2260
TIM-3 Participates in the Invasion and Metastasis of Nasopharyngeal Carcinoma via SMAD7/SMAD2/SNAIL1 Axis-Mediated Epithelial-Mesenchymal Transition.
Xiao Y, Qing J, Li B, Chen L, Nong S, Yang W, Tang X, Chen Z
OncoTargets and therapy 2020;13:1993-2006
OncoTargets and therapy 2020;13:1993-2006
Prognostic Significance and Related Mechanisms of Hexokinase 1 in Ovarian Cancer.
Li Y, Tian H, Luo H, Fu J, Jiao Y, Li Y
OncoTargets and therapy 2020;13:11583-11594
OncoTargets and therapy 2020;13:11583-11594
CircHIPK3 Promotes Gemcitabine (GEM) Resistance in Pancreatic Cancer Cells by Sponging miR-330-5p and Targets RASSF1.
Liu Y, Xia L, Dong L, Wang J, Xiao Q, Yu X, Zhu H
Cancer management and research 2020;12:921-929
Cancer management and research 2020;12:921-929
Downregulation of Immortalization-Upregulated Protein Suppresses the Progression of Breast Cancer Cell Lines by Regulating Epithelial-Mesenchymal Transition.
Wen J, Lin L, Lin B, Xia E, Qu J, Wang O
Cancer management and research 2020;12:8631-8642
Cancer management and research 2020;12:8631-8642
Blocking circ_0000520 Suppressed Breast Cancer Cell Growth, Migration and Invasion Partially via miR-1296/SP1 Axis Both in vitro and in vivo.
Zang H, Li Y, Zhang X, Huang G
Cancer management and research 2020;12:7783-7795
Cancer management and research 2020;12:7783-7795
KLHL22 Regulates the EMT and Proliferation in Colorectal Cancer Cells in Part via the Wnt/β-Catenin Signaling Pathway.
Song Y, Yuan H, Wang J, Wu Y, Xiao Y, Mao S
Cancer management and research 2020;12:3981-3993
Cancer management and research 2020;12:3981-3993
METTL14 Inhibits Hepatocellular Carcinoma Metastasis Through Regulating EGFR/PI3K/AKT Signaling Pathway in an m6A-Dependent Manner.
Shi Y, Zhuang Y, Zhang J, Chen M, Wu S
Cancer management and research 2020;12:13173-13184
Cancer management and research 2020;12:13173-13184
Cytokine TNF-α promotes invasion and metastasis of gastric cancer by down-regulating Pentraxin3.
Cui X, Zhang H, Cao A, Cao L, Hu X
Journal of Cancer 2020;11(7):1800-1807
Journal of Cancer 2020;11(7):1800-1807
TRIM67 Promotes the Proliferation, Migration, and Invasion of Non-Small-Cell Lung Cancer by Positively Regulating the Notch Pathway.
Jiang J, Ren H, Xu Y, Wudu M, Wang Q, Liu Z, Su H, Jiang X, Zhang Y, Zhang B, Qiu X
Journal of Cancer 2020;11(5):1240-1249
Journal of Cancer 2020;11(5):1240-1249
NFE2L3 promotes malignant behavior and EMT of human hepatocellular carcinoma (HepG2) cells via Wnt/β‑catenin pathway.
Ren Y, Wang Y, Hao S, Yang Y, Xiong W, Qiu L, Tao J, Tang A
Journal of Cancer 2020;11(23):6939-6949
Journal of Cancer 2020;11(23):6939-6949
Ubiquitin specific peptidase 5 enhances STAT3 signaling and promotes migration and invasion in Pancreatic Cancer.
Lian J, Liu C, Guan X, Wang B, Yao Y, Su D, Ma Y, Fang L, Zhang Y
Journal of Cancer 2020;11(23):6802-6811
Journal of Cancer 2020;11(23):6802-6811
TNFAIP8 promotes the migration of clear cell renal cell carcinoma by regulating the EMT.
Zhong M, Zhu M, Liu Y, Lin Y, Wang L, Ye Y, Chen H, Yang Y, Zhuang G, Huang J
Journal of Cancer 2020;11(10):3061-3071
Journal of Cancer 2020;11(10):3061-3071
P4HA2 contributes to cervical cancer progression via inducing epithelial-mesenchymal transition.
Cao Y, Han Q, Li J, Jia Y, Zhang R, Shi H
Journal of Cancer 2020;11(10):2788-2799
Journal of Cancer 2020;11(10):2788-2799
Hyperoside Attenuates Bleomycin-Induced Pulmonary Fibrosis Development in Mice.
Huang J, Tong X, Zhang L, Zhang Y, Wang L, Wang D, Zhang S, Fan H
Frontiers in pharmacology 2020;11:550955
Frontiers in pharmacology 2020;11:550955
SMYD2 suppresses APC2 expression to activate the Wnt/β-catenin pathway and promotes epithelial-mesenchymal transition in colorectal cancer.
Meng F, Liu X, Lin C, Xu L, Liu J, Zhang P, Zhang X, Song J, Yan Y, Ren Z, Zhang Y
American journal of cancer research 2020;10(3):997-1011
American journal of cancer research 2020;10(3):997-1011
Non-canonical signaling pathway of SNAI2 induces EMT in ovarian cancer cells by suppressing miR-222-3p transcription and upregulating PDCD10.
Fan L, Lei H, Zhang S, Peng Y, Fu C, Shu G, Yin G
Theranostics 2020;10(13):5895-5913
Theranostics 2020;10(13):5895-5913
Liquid Biopsy of Extracellular Vesicle-Derived miR-193a-5p in Colorectal Cancer and Discovery of Its Tumor-Suppressor Functions.
Wei R, Chen L, Qin D, Guo Q, Zhu S, Li P, Min L, Zhang S
Frontiers in oncology 2020;10:1372
Frontiers in oncology 2020;10:1372
LSD1 Promotes Bladder Cancer Progression by Upregulating LEF1 and Enhancing EMT.
Xie Q, Tang T, Pang J, Xu J, Yang X, Wang L, Huang Y, Huang Z, Liu G, Tong D, Zhang Y, Wang L, Zhang D, Lan W, Liu Q, Jiang J
Frontiers in oncology 2020;10:1234
Frontiers in oncology 2020;10:1234
Musashi2 promotes the progression of pancreatic cancer through a novel ISYNA1-p21/ZEB-1 pathway.
Zhou L, Sheng W, Jia C, Shi X, Cao R, Wang G, Lin Y, Zhu F, Dong Q, Dong M
Journal of cellular and molecular medicine 2020 Sep;24(18):10560-10572
Journal of cellular and molecular medicine 2020 Sep;24(18):10560-10572
AKR1C2 acts as a targetable oncogene in esophageal squamous cell carcinoma via activating PI3K/AKT signaling pathway.
Zhang ZF, Huang TJ, Zhang XK, Xie YJ, Lin ST, Luo FF, Meng DF, Hu H, Wang J, Peng LX, Qian CN, Cheng C, Huang BJ
Journal of cellular and molecular medicine 2020 Sep;24(17):9999-10012
Journal of cellular and molecular medicine 2020 Sep;24(17):9999-10012
Circular RNA hsa_circ_0005556 Accelerates Gastric Cancer Progression by Sponging miR-4270 to Increase MMP19 Expression.
Shen D, Zhao H, Zeng P, Song J, Yang Y, Gu X, Ji Q, Zhao W
Journal of gastric cancer 2020 Sep;20(3):300-312
Journal of gastric cancer 2020 Sep;20(3):300-312
BAIAP2L2 promotes the progression of gastric cancer via AKT/mTOR and Wnt3a/β-catenin signaling pathways.
Liu J, Shangguan Y, Sun J, Cong W, Xie Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Sep;129:110414
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Sep;129:110414
Novel long non-coding RNA LINC02323 promotes epithelial-mesenchymal transition and metastasis via sponging miR-1343-3p in lung adenocarcinoma.
Zhang X, Du L, Han J, Li X, Wang H, Zheng G, Wang Y, Yang Y, Hu Y, Wang C
Thoracic cancer 2020 Sep;11(9):2506-2516
Thoracic cancer 2020 Sep;11(9):2506-2516
Circular RNA circREPS2 Acts as a Sponge of miR-558 to Suppress Gastric Cancer Progression by Regulating RUNX3/β-catenin Signaling.
Guo X, Dai X, Liu J, Cheng A, Qin C, Wang Z
Molecular therapy. Nucleic acids 2020 Sep 4;21:577-591
Molecular therapy. Nucleic acids 2020 Sep 4;21:577-591
LncRNA Mical2/miR-203a-3p sponge participates in epithelial-mesenchymal transition by targeting p66Shc in liver fibrosis.
Zhao Y, Wang Z, Zhou J, Feng D, Li Y, Hu Y, Zhang F, Chen Z, Wang G, Ma X, Tian X, Yao J
Toxicology and applied pharmacology 2020 Sep 15;403:115125
Toxicology and applied pharmacology 2020 Sep 15;403:115125
The AKT/GSK3-Mediated Slug Expression Contributes to Oxaliplatin Resistance in Colorectal Cancer via Upregulation of ERCC1.
Wei W, Ma XD, Jiang GM, Shi B, Zhong W, Sun CL, Zhao L, Hou YJ, Wang H
Oncology research 2020 Sep 1;28(4):423-438
Oncology research 2020 Sep 1;28(4):423-438
MEST promotes bladder cancer cell proliferation, migration and invasion via STAT3/Twist-1-mediated EMT.
Zhao C, Hu X, Tong S, Mo M, He W, Wang L, Li Y
Translational cancer research 2020 Oct;9(10):6178-6188
Translational cancer research 2020 Oct;9(10):6178-6188
MYCT1 inhibits the EMT and migration of laryngeal cancer cells via the SP1/miR-629-3p/ESRP2 pathway.
Yue PJ, Sun YY, Li YH, Xu ZM, Fu WN
Cellular signalling 2020 Oct;74:109709
Cellular signalling 2020 Oct;74:109709
Blocking NFATc3 ameliorates azoxymethane/dextran sulfate sodium induced colitis-associated colorectal cancer in mice via the inhibition of inflammatory responses and epithelial-mesenchymal transition.
Lin Y, Koumba MH, Qu S, Wang D, Lin L
Cellular signalling 2020 Oct;74:109707
Cellular signalling 2020 Oct;74:109707
Melatonin synergizes BRAF-targeting agent dabrafenib for the treatment of anaplastic thyroid cancer by inhibiting AKT/hTERT signalling.
Liao Y, Gao Y, Chang A, Li Z, Wang H, Cao J, Gu W, Tang R
Journal of cellular and molecular medicine 2020 Oct;24(20):12119-12130
Journal of cellular and molecular medicine 2020 Oct;24(20):12119-12130
Members of the miR-30 family inhibit the epithelial-to-mesenchymal transition of non-small-cell lung cancer cells by suppressing XB130 expression levels.
Song K, Jiang Y, Zhao Y, Xie Y, Zhou J, Yu W, Wang Q
Oncology letters 2020 Oct;20(4):68
Oncology letters 2020 Oct;20(4):68
Micheliolide suppresses the viability, migration and invasion of U251MG cells via the NF-κB signaling pathway.
Feng D, Liu M, Liu Y, Zhao X, Sun H, Zheng X, Zhu J, Shang F
Oncology letters 2020 Oct;20(4):67
Oncology letters 2020 Oct;20(4):67
A novel metastatic promoter CEMIP and its downstream molecular targets and signaling pathway of cellular migration and invasion in SCLC cells based on proteome analysis.
Li L, Pan Y, Mo X, Wei T, Song J, Luo M, Huang G, Teng C, Liang K, Mao N, Yang J
Journal of cancer research and clinical oncology 2020 Oct;146(10):2519-2534
Journal of cancer research and clinical oncology 2020 Oct;146(10):2519-2534
Calreticulin promotes EMT in pancreatic cancer via mediating Ca(2+) dependent acute and chronic endoplasmic reticulum stress.
Sheng W, Wang G, Tang J, Shi X, Cao R, Sun J, Lin YH, Jia C, Chen C, Zhou J, Dong M
Journal of experimental & clinical cancer research : CR 2020 Oct 7;39(1):209
Journal of experimental & clinical cancer research : CR 2020 Oct 7;39(1):209
CUEDC1 inhibits epithelial-mesenchymal transition via the TβRI/Smad signaling pathway and suppresses tumor progression in non-small cell lung cancer.
Cui Y, Song Y, Yan S, Cao M, Huang J, Jia D, Liu Y, Zhang S, Fan W, Cai L, Li C, Xing Y
Aging 2020 Oct 25;12(20):20047-20068
Aging 2020 Oct 25;12(20):20047-20068
IL-32 induces epithelial-mesenchymal transition by triggering endoplasmic reticulum stress in A549 cells.
Gong L, Liu G, Zhu H, Li C, Li P, Liu C, Tang H, Wu K, Wu J, Liu D, Tang X
BMC pulmonary medicine 2020 Oct 23;20(1):278
BMC pulmonary medicine 2020 Oct 23;20(1):278
PRMT5/Wnt4 axis promotes lymph-node metastasis and proliferation of laryngeal carcinoma.
Wang N, Yan H, Wu D, Zhao Z, Chen X, Long Q, Zhang C, Wang X, Deng W, Liu X
Cell death & disease 2020 Oct 15;11(10):864
Cell death & disease 2020 Oct 15;11(10):864
GATA6 promotes epithelial-mesenchymal transition and metastasis through MUC1/β-catenin pathway in cholangiocarcinoma.
Deng X, Jiang P, Chen J, Li J, Li D, He Y, Jiang Y, Zhang Y, Xu S, Li X, Wang S, Tian F
Cell death & disease 2020 Oct 15;11(10):860
Cell death & disease 2020 Oct 15;11(10):860
MyoD1 suppresses cell migration and invasion by inhibiting FUT4 transcription in human gastric cancer cells.
Wu F, Qin Y, Jiang Q, Zhang J, Li F, Li Q, Wang X, Gao Y, Miao J, Guo C, Yang Y, Ni L, Liu L, Zhang S, Huang C
Cancer gene therapy 2020 Nov;27(10-11):773-784
Cancer gene therapy 2020 Nov;27(10-11):773-784
LncRNA HOTTIP promotes the proliferation and invasion of ovarian cancer cells by activating the MEK/ERK pathway.
Liu J, Hu HB, Liu YM, Li FX, Zhang LP, Liao ZM
Molecular medicine reports 2020 Nov;22(5):3667-3676
Molecular medicine reports 2020 Nov;22(5):3667-3676
SUMO4 small interfering RNA attenuates invasion and migration via the JAK2/STAT3 pathway in non-small cell lung cancer cells.
Liang JX, Gao W, Zeng XW, Cheng GP, Cai L, Tao KY, Yang X
Oncology letters 2020 Nov;20(5):225
Oncology letters 2020 Nov;20(5):225
SNHG1 promotes proliferation, migration and invasion of bladder cancer cells via the PI3K/AKT signaling pathway.
Du Q, Chen J
Experimental and therapeutic medicine 2020 Nov;20(5):110
Experimental and therapeutic medicine 2020 Nov;20(5):110
Wnt/β-Catenin Signaling Axis Is Required for TFEB-Mediated Gastric Cancer Metastasis and Epithelial-Mesenchymal Transition.
Li S, Liu F, Xu L, Li C, Yang X, Guo B, Gu J, Wang L
Molecular cancer research : MCR 2020 Nov;18(11):1650-1659
Molecular cancer research : MCR 2020 Nov;18(11):1650-1659
OXPHOS-dependent metabolic reprogramming prompts metastatic potential of breast cancer cells under osteogenic differentiation.
Hu Y, Xu W, Zeng H, He Z, Lu X, Zuo D, Qin G, Chen W
British journal of cancer 2020 Nov;123(11):1644-1655
British journal of cancer 2020 Nov;123(11):1644-1655
Deficiency of pseudogene UPAT leads to hepatocellular carcinoma progression and forms a positive feedback loop with ZEB1.
Xiang L, Huang X, Wang S, Ou H, Chen Z, Hu Z, Huang Y, Li X, Yuan Y, Yang D
Cancer science 2020 Nov;111(11):4102-4117
Cancer science 2020 Nov;111(11):4102-4117
Isolation of DNA aptamers targeting N-cadherin and high-efficiency capture of circulating tumor cells by using dual aptamers.
Gao T, Ding P, Li W, Wang Z, Lin Q, Pei R
Nanoscale 2020 Nov 19;12(44):22574-22585
Nanoscale 2020 Nov 19;12(44):22574-22585
Exosome-derived ENO1 regulates integrin α6β4 expression and promotes hepatocellular carcinoma growth and metastasis.
Jiang K, Dong C, Yin Z, Li R, Mao J, Wang C, Zhang J, Gao Z, Liang R, Wang Q, Wang L
Cell death & disease 2020 Nov 12;11(11):972
Cell death & disease 2020 Nov 12;11(11):972
Serum KIAA1199 is an advanced-stage prognostic biomarker and metastatic oncogene in cholangiocarcinoma.
Zhai X, Wang W, Ma Y, Zeng Y, Dou D, Fan H, Song J, Yu X, Xin D, Du G, Jiang Z, Zhang H, Zhang X, Jin B
Aging 2020 Nov 10;12(23):23761-23777
Aging 2020 Nov 10;12(23):23761-23777
Sirtuin 6 attenuates epithelial-mesenchymal transition by suppressing the TGF-β1/Smad3 pathway and c-Jun in asthma models.
Liu F, Shang YX
International immunopharmacology 2020 May;82:106333
International immunopharmacology 2020 May;82:106333
XB130, regulated by miR-203, miR-219, and miR-4782-3p, mediates the proliferation and metastasis of non-small-cell lung cancer cells.
Wang Q, Yang G, Jiang Y, Luo M, Li C, Zhao Y, Xie Y, Song K, Zhou J
Molecular carcinogenesis 2020 May;59(5):557-568
Molecular carcinogenesis 2020 May;59(5):557-568
MiR-645 promotes invasiveness, metastasis and tumor growth in colorectal cancer by targeting EFNA5.
Li S, Hou X, Wu C, Han L, Li Q, Wang J, Luo S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109889
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109889
BMP8A promotes survival and drug resistance via Nrf2/TRIM24 signaling pathway in clear cell renal cell carcinoma.
Yu YP, Cai LC, Wang XY, Cheng SY, Zhang DM, Jian WG, Wang TD, Yang JK, Yang KB, Zhang C
Cancer science 2020 May;111(5):1555-1566
Cancer science 2020 May;111(5):1555-1566
PHLDA2 regulates EMT and autophagy in colorectal cancer via the PI3K/AKT signaling pathway.
Ma Z, Lou S, Jiang Z
Aging 2020 May 8;12(9):7985-8000
Aging 2020 May 8;12(9):7985-8000
MAY, a novel tubulin inhibitor, induces cell apoptosis in A549 and A549/Taxol cells and inhibits epithelial-mesenchymal transition in A549/Taxol cells.
Du J, Li J, Gao M, Guan Q, Liu T, Wu Y, Li Z, Zuo D, Zhang W, Wu Y
Chemico-biological interactions 2020 May 25;323:109074
Chemico-biological interactions 2020 May 25;323:109074
IGF-1 promotes multiple myeloma progression through PI3K/Akt-mediated epithelial-mesenchymal transition.
Peng Y, Li F, Zhang P, Wang X, Shen Y, Feng Y, Jia Y, Zhang R, Hu J, He A
Life sciences 2020 May 15;249:117503
Life sciences 2020 May 15;249:117503
A dual receptors-targeting and size-switchable "cluster bomb" co-loading chemotherapeutic and transient receptor potential ankyrin 1 (TRPA-1) inhibitor for treatment of triple negative breast cancer.
Wang Y, Yin S, Mei L, Yang Y, Xu S, He X, Wang M, Li M, Zhang Z, He Q
Journal of controlled release : official journal of the Controlled Release Society 2020 May 10;321:71-83
Journal of controlled release : official journal of the Controlled Release Society 2020 May 10;321:71-83
Gremlin-1 is a key regulator of endothelial-to-mesenchymal transition in human pulmonary artery endothelial cells.
Zhang Y, Zhang M, Xie W, Wan J, Tao X, Liu M, Zhen Y, Lin F, Wu B, Zhai Z, Wang C
Experimental cell research 2020 May 1;390(1):111941
Experimental cell research 2020 May 1;390(1):111941
MiR-328-3p inhibits cell proliferation and metastasis in colorectal cancer by targeting Girdin and inhibiting the PI3K/Akt signaling pathway.
Pan S, Ren F, Li L, Liu D, Li Y, Wang A, Li W, Dong Y, Guo W
Experimental cell research 2020 May 1;390(1):111939
Experimental cell research 2020 May 1;390(1):111939
PLEK2 mediates metastasis and vascular invasion via the ubiquitin-dependent degradation of SHIP2 in non-small cell lung cancer.
Wu DM, Deng SH, Zhou J, Han R, Liu T, Zhang T, Li J, Chen JP, Xu Y
International journal of cancer 2020 May 1;146(9):2563-2575
International journal of cancer 2020 May 1;146(9):2563-2575
Downregulated placental expression of linc00468 contributes to trophoblast dysfunction by inducing epithelial-mesenchymal transition.
Wang S, Wu D, Xu Y, Cao Y, Wang J, Zhang Y, Yang N, Sun L
Annals of translational medicine 2020 Mar;8(6):333
Annals of translational medicine 2020 Mar;8(6):333
Rosmarinic acid exerts an anticancer effect on osteosarcoma cells by inhibiting DJ-1 via regulation of the PTEN-PI3K-Akt signaling pathway.
Ma Z, Yang J, Yang Y, Wang X, Chen G, Shi A, Lu Y, Jia S, Kang X, Lu L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2020 Mar;68:153186
Phytomedicine : international journal of phytotherapy and phytopharmacology 2020 Mar;68:153186
MicroRNA‑137 suppresses the proliferation, migration and invasion of cholangiocarcinoma cells by targeting WNT2B.
Chen T, Lei S, Zeng Z, Pan S, Zhang J, Xue Y, Sun Y, Lan J, Xu S, Mao D, Guo B
International journal of molecular medicine 2020 Mar;45(3):886-896
International journal of molecular medicine 2020 Mar;45(3):886-896
Linc00261 inhibits metastasis and the WNT signaling pathway of pancreatic cancer by regulating a miR‑552‑5p/FOXO3 axis.
Chen T, Lei S, Zeng Z, Zhang J, Xue Y, Sun Y, Lan J, Xu S, Mao D, Guo B
Oncology reports 2020 Mar;43(3):930-942
Oncology reports 2020 Mar;43(3):930-942
Interleukin 1β/1RA axis in colorectal cancer regulates tumor invasion, proliferation and apoptosis via autophagy.
Chen Y, Yang Z, Deng B, Wu D, Quan Y, Min Z
Oncology reports 2020 Mar;43(3):908-918
Oncology reports 2020 Mar;43(3):908-918
Quantitative proteomic analysis reveals that Luks-PV exerts antitumor activity by regulating the key proteins and metabolic pathways in HepG2 cells.
Zhao CC, Yu WW, Qi YJ, Xu LF, Wang ZR, Qiang YW, Ma F, Ma XL
Anti-cancer drugs 2020 Mar;31(3):223-230
Anti-cancer drugs 2020 Mar;31(3):223-230
Decreasing New York esophageal squamous cell carcinoma 1 expression inhibits multiple myeloma growth and osteolytic lesions.
Li F, Zhao F, Li M, Pan M, Shi F, Xu H, Zheng D, Wang L, Dou J
Journal of cellular physiology 2020 Mar;235(3):2183-2194
Journal of cellular physiology 2020 Mar;235(3):2183-2194
Retinol-Binding Protein 4 Accelerates Metastatic Spread and Increases Impairment of Blood Flow in Mouse Mammary Gland Tumors.
Papiernik D, Urbaniak A, Kłopotowska D, Nasulewicz-Goldeman A, Ekiert M, Nowak M, Jarosz J, Cuprych M, Strzykalska A, Ugorski M, Matkowski R, Wietrzyk J
Cancers 2020 Mar 7;12(3)
Cancers 2020 Mar 7;12(3)
Transcription co-activator P300 activates Elk1-aPKC-ι signaling mediated epithelial-to-mesenchymal transition and malignancy in hepatocellular carcinoma.
Ma C, Huang S, Xu L, Tian L, Yang Y, Wang J
Oncogenesis 2020 Mar 6;9(3):32
Oncogenesis 2020 Mar 6;9(3):32
Long non-coding RNA HAL suppresses the migration and invasion of serous ovarian cancer by inhibiting EMT signaling pathway.
Wu K, Li L, Li L, Wang D
Bioscience reports 2020 Mar 27;40(3)
Bioscience reports 2020 Mar 27;40(3)
Upregulated NTF4 in colorectal cancer promotes tumor development via regulating autophagy.
Yang Z, Chen Y, Wei X, Wu D, Min Z, Quan Y
International journal of oncology 2020 Jun;56(6):1442-1454
International journal of oncology 2020 Jun;56(6):1442-1454
Inhibition of miR-574-5p suppresses cell growth and metastasis and enhances chemosensitivity by targeting RNA binding protein QKI in cervical cancer cells.
Tong R, Zhang J, Wang C, Li Q, Wang L, Ju M
Naunyn-Schmiedeberg's archives of pharmacology 2020 Jun;393(6):951-966
Naunyn-Schmiedeberg's archives of pharmacology 2020 Jun;393(6):951-966
Effect of STAT3 mediated epigenetic regulation in pre-eclampsia: an analysis of trial data.
Zhang XL, Pan J, Wang G, Li H, Wang JL, Jiang XM, Zhao XY
European review for medical and pharmacological sciences 2020 Jun;24(11):5843-5855
European review for medical and pharmacological sciences 2020 Jun;24(11):5843-5855
HnRNP A1 - mediated alternative splicing of CCDC50 contributes to cancer progression of clear cell renal cell carcinoma via ZNF395.
Sun G, Zhou H, Chen K, Zeng J, Zhang Y, Yan L, Yao W, Hu J, Wang T, Xing J, Xiao K, Wu L, Ye Z, Xu H
Journal of experimental & clinical cancer research : CR 2020 Jun 19;39(1):116
Journal of experimental & clinical cancer research : CR 2020 Jun 19;39(1):116
ARHGEF10L expression regulates cell proliferation and migration in gastric tumorigenesis.
Wang DW, Tang JY, Zhang GQ, Chang XT
Bioscience, biotechnology, and biochemistry 2020 Jul;84(7):1362-1372
Bioscience, biotechnology, and biochemistry 2020 Jul;84(7):1362-1372
Cyclovirobuxine D inhibits colorectal cancer tumorigenesis via the CTHRC1‑AKT/ERK‑Snail signaling pathway.
Jiang F, Chen Y, Ren S, Li Z, Sun K, Xing Y, Zhu Y, Piao D
International journal of oncology 2020 Jul;57(1):183-196
International journal of oncology 2020 Jul;57(1):183-196
PCNP promotes ovarian cancer progression by accelerating β-catenin nuclear accumulation and triggering EMT transition.
Dong P, Fu H, Chen L, Zhang S, Zhang X, Li H, Wu D, Ji X
Journal of cellular and molecular medicine 2020 Jul;24(14):8221-8235
Journal of cellular and molecular medicine 2020 Jul;24(14):8221-8235
LncRNA MALAT1 affects the migration and invasion of trophoblast cells by regulating FOS expression in early-onset preeclampsia.
Li Q, Wang T, Huang S, Zuo Q, Jiang Z, Yang N, Sun L
Pregnancy hypertension 2020 Jul;21:50-57
Pregnancy hypertension 2020 Jul;21:50-57
PRR11 and SKA2 promote the proliferation, migration and invasion of esophageal carcinoma cells.
Chen J, Yang HM, Zhou HC, Peng RR, Niu ZX, Kang CY
Oncology letters 2020 Jul;20(1):639-646
Oncology letters 2020 Jul;20(1):639-646
miR-96-5p regulated TGF-β/SMAD signaling pathway and suppressed endometrial cell viability and migration via targeting TGFBR1.
Chen S, Luo Y, Cui L, Yang Q
Cell cycle (Georgetown, Tex.) 2020 Jul;19(14):1740-1753
Cell cycle (Georgetown, Tex.) 2020 Jul;19(14):1740-1753
SLC7A2 serves as a potential biomarker and therapeutic target for ovarian cancer.
Sun T, Bi F, Liu Z, Yang Q
Aging 2020 Jul 9;12(13):13281-13296
Aging 2020 Jul 9;12(13):13281-13296
PD-L1 promotes tumor growth and progression by activating WIP and β-catenin signaling pathways and predicts poor prognosis in lung cancer.
Yu W, Hua Y, Qiu H, Hao J, Zou K, Li Z, Hu S, Guo P, Chen M, Sui S, Xiong Y, Li F, Lu J, Guo W, Luo G, Deng W
Cell death & disease 2020 Jul 6;11(7):506
Cell death & disease 2020 Jul 6;11(7):506
The cross-talk between DDR1 and STAT3 promotes the development of hepatocellular carcinoma.
Lin Y, Jin H, Wu X, Jian Z, Zou X, Huang J, Guan R, Wei X
Aging 2020 Jul 27;12(14):14391-14405
Aging 2020 Jul 27;12(14):14391-14405
Nucleus-located PDK1 regulates growth, invasion and migration of breast cancer cells.
Gan D, Yue S, Jiang Y, Zhang D, Shi H, Qian H, Zhou T, Fang W, Yao M, Zuo G, Chen T
Life sciences 2020 Jul 15;253:117722
Life sciences 2020 Jul 15;253:117722
CPEB3 inhibits epithelial-mesenchymal transition by disrupting the crosstalk between colorectal cancer cells and tumor-associated macrophages via IL-6R/STAT3 signaling.
Zhong Q, Fang Y, Lai Q, Wang S, He C, Li A, Liu S, Yan Q
Journal of experimental & clinical cancer research : CR 2020 Jul 11;39(1):132
Journal of experimental & clinical cancer research : CR 2020 Jul 11;39(1):132
A combination of Citrus reticulata peel and black tea inhibits migration and invasion of liver cancer via PI3K/AKT and MMPs signaling pathway.
Wen S, Sun L, An R, Zhang W, Xiang L, Li Q, Lai X, Huo M, Li D, Sun S
Molecular biology reports 2020 Jan;47(1):507-519
Molecular biology reports 2020 Jan;47(1):507-519
Spondin 2 promotes the proliferation, migration and invasion of gastric cancer cells.
Lu H, Feng Y, Hu Y, Guo Y, Liu Y, Mao Q, Xue W
Journal of cellular and molecular medicine 2020 Jan;24(1):98-113
Journal of cellular and molecular medicine 2020 Jan;24(1):98-113
Endoplasmic reticulum stress regulates epithelial‑mesenchymal transition in human lens epithelial cells.
Zhou S, Yang J, Wang M, Zheng D, Liu Y
Molecular medicine reports 2020 Jan;21(1):173-180
Molecular medicine reports 2020 Jan;21(1):173-180
Norepinephrine transporter promotes the invasion of human colon cancer cells.
Zhang H, Miao J, Li F, Xue W, Tang K, Zhao X, Jing X, Zhang J, Huang C, Hou N, Han J
Oncology letters 2020 Jan;19(1):824-832
Oncology letters 2020 Jan;19(1):824-832
Desloratadine, a Novel Antigrowth Reagent for Bladder Cancer.
Ma J, Qi J, Li S, Zhang C, Wang H, Shao L, Yuan X, Sha Q
Technology in cancer research & treatment 2020 Jan-Dec;19:1533033820926591
Technology in cancer research & treatment 2020 Jan-Dec;19:1533033820926591
Aspirin enhances the sensitivity of colon cancer cells to cisplatin by abrogating the binding of NF-κB to the COX-2 promoter.
Jiang W, Yan Y, Chen M, Luo G, Hao J, Pan J, Hu S, Guo P, Li W, Wang R, Zuo Y, Sun Y, Sui S, Yu W, Pan Z, Zou K, Zheng Z, Deng W, Wu X, Guo W
Aging 2020 Jan 6;12(1):611-627
Aging 2020 Jan 6;12(1):611-627
UBE2O promotes the proliferation, EMT and stemness properties of breast cancer cells through the UBE2O/AMPKα2/mTORC1-MYC positive feedback loop.
Liu X, Ma F, Liu C, Zhu K, Li W, Xu Y, Li G, Niu Z, Liu J, Chen D, Li Z, Fu Y, Qian C
Cell death & disease 2020 Jan 6;11(1):10
Cell death & disease 2020 Jan 6;11(1):10
Protective effects of Salidroside on spermatogenesis in streptozotocin induced type-1 diabetic male mice by inhibiting oxidative stress mediated blood-testis barrier damage.
Jiang YP, Ye RJ, Yang JM, Liu N, Zhang WJ, Ma L, Sun T, Niu JG, Zheng P, Yu JQ
Chemico-biological interactions 2020 Jan 5;315:108869
Chemico-biological interactions 2020 Jan 5;315:108869
Graphene Oxide Promotes Cancer Metastasis through Associating with Plasma Membrane To Promote TGF-β Signaling-Dependent Epithelial-Mesenchymal Transition.
Zhu J, Li B, Xu M, Liu R, Xia T, Zhang Z, Xu Y, Liu S
ACS nano 2020 Jan 28;14(1):818-827
ACS nano 2020 Jan 28;14(1):818-827
Telmisartan inhibits oxalate and calcium oxalate crystal-induced epithelial-mesenchymal transformation via PPAR-γ-AKT/STAT3/p38 MAPK-Snail pathway.
Liu Y, Chen S, Liu J, Jin Y, Yu S, An R
Life sciences 2020 Jan 15;241:117108
Life sciences 2020 Jan 15;241:117108
SPARCL1 impedes trophoblast migration and invasion by down-regulating ERK phosphorylation and AP-1 production and altering EMT-related molecule expression.
Liu X, Zhao J, Luan X, Li S, Zhai J, Liu J, Du Y
Placenta 2020 Jan 1;89:33-41
Placenta 2020 Jan 1;89:33-41
CCND1, NOP14 and DNMT3B are involved in miR-502-5p-mediated inhibition of cell migration and proliferation in bladder cancer.
Ying Y, Li J, Xie H, Yan H, Jin K, He L, Ma X, Wu J, Xu X, Fang J, Wang X, Zheng X, Liu B, Xie L
Cell proliferation 2020 Feb;53(2):e12751
Cell proliferation 2020 Feb;53(2):e12751
Epiregulin promotes trophoblast epithelial-mesenchymal transition through poFUT1 and O-fucosylation by poFUT1 on uPA.
Cui X, Wang H, Li Y, Chen T, Liu S, Yan Q
Cell proliferation 2020 Feb;53(2):e12745
Cell proliferation 2020 Feb;53(2):e12745
miR-1294 alleviates epithelial-mesenchymal transition by repressing FOXK1 in gastric cancer.
Wang Y, Liu G, Sun S, Qin J
Genes & genomics 2020 Feb;42(2):217-224
Genes & genomics 2020 Feb;42(2):217-224
The reciprocal interaction between tumor cells and activated fibroblasts mediated by TNF-α/IL-33/ST2L signaling promotes gastric cancer metastasis.
Zhou Q, Wu X, Wang X, Yu Z, Pan T, Li Z, Chang X, Jin Z, Li J, Zhu Z, Liu B, Su L
Oncogene 2020 Feb;39(7):1414-1428
Oncogene 2020 Feb;39(7):1414-1428
α5-nAChR contributes to epithelial-mesenchymal transition and metastasis by regulating Jab1/Csn5 signalling in lung cancer.
Chen X, Jia Y, Zhang Y, Zhou D, Sun H, Ma X
Journal of cellular and molecular medicine 2020 Feb;24(4):2497-2506
Journal of cellular and molecular medicine 2020 Feb;24(4):2497-2506
Expression and clinical significance of WWOX, Elf5, Snail1 and EMT related factors in epithelial ovarian cancer.
Hu Y, Yan Y, Xu Y, Yang H, Fang L, Liu Y, Li X, Li Q, Yan H
Oncology letters 2020 Feb;19(2):1281-1290
Oncology letters 2020 Feb;19(2):1281-1290
PLAGL2 promotes epithelial-mesenchymal transition and mediates colorectal cancer metastasis via β-catenin-dependent regulation of ZEB1.
Wu L, Zhou Z, Han S, Chen J, Liu Z, Zhang X, Yuan W, Ji J, Shu X
British journal of cancer 2020 Feb;122(4):578-589
British journal of cancer 2020 Feb;122(4):578-589
The lncRNA FEZF1-AS1 Promotes the Progression of Colorectal Cancer Through Regulating OTX1 and Targeting miR-30a-5p.
Li J, Zhao LM, Zhang C, Li M, Gao B, Hu XH, Cao J, Wang GY
Oncology research 2020 Feb 7;28(1):51-63
Oncology research 2020 Feb 7;28(1):51-63
Interaction of calcium binding protein S100A16 with myosin-9 promotes cytoskeleton reorganization in renal tubulointerstitial fibrosis.
Sun H, Zhao A, Li M, Dong H, Sun Y, Zhang X, Zhu Q, Bukhari AA, Cao C, Su D, Liu Y, Liang X
Cell death & disease 2020 Feb 24;11(2):146
Cell death & disease 2020 Feb 24;11(2):146
Promotion of esophageal adenocarcinoma metastasis via Wnt/ß-catenin signal pathway by sorting nexins 3.
Pan B, Liu L, Hu X, Sun X, Zhu Y, Zhang T, Wei D, Guo Y, Shan J
Journal of gastroenterology and hepatology 2020 Dec;35(12):2131-2139
Journal of gastroenterology and hepatology 2020 Dec;35(12):2131-2139
Circ_0075829 facilitates the progression of pancreatic carcinoma by sponging miR-1287-5p and activating LAMTOR3 signalling.
Zhang X, Xue C, Cui X, Zhou Z, Fu Y, Yin X, Wu S, Gong Y, Liu Y, Zhu C, Qin X
Journal of cellular and molecular medicine 2020 Dec;24(24):14596-14607
Journal of cellular and molecular medicine 2020 Dec;24(24):14596-14607
MicroRNA-1236-3p inhibits human osteosarcoma growth.
Li J, Chen J, Hu Z, Xu W
Oncology letters 2020 Dec;20(6):367
Oncology letters 2020 Dec;20(6):367
Down-regulation of lncRNA DNAJC3-AS1 inhibits colon cancer via regulating miR-214-3p/LIVIN axis.
Han B, Ge Y, Cui J, Liu B
Bioengineered 2020 Dec;11(1):524-535
Bioengineered 2020 Dec;11(1):524-535
Epithelial to Mesenchymal Transition (EMT) in a Laryngeal Squamous Cell Carcinoma of a Horse: Future Perspectives.
Armando F, Godizzi F, Razzuoli E, Leonardi F, Angelone M, Corradi A, Meloni D, Ferrari L, Passeri B
Animals : an open access journal from MDPI 2020 Dec 7;10(12)
Animals : an open access journal from MDPI 2020 Dec 7;10(12)
HOXB9 enhances the ability of lung cancer cells to penetrate the blood-brain barrier.
Zheng H, Li C, Li Z, Zhu K, Bao H, Xiong J, Liang P
Aging 2020 Dec 19;13(4):4999-5019
Aging 2020 Dec 19;13(4):4999-5019
S119N Mutation of the E3 Ubiquitin Ligase SPOP Suppresses SLC7A1 Degradation to Regulate Hepatoblastoma Progression.
He W, Zhang J, Liu B, Liu X, Liu G, Xie L, He J, Wei M, Li K, Ma J, Dong R, Ma D, Dong K, Ye M
Molecular therapy oncolytics 2020 Dec 16;19:149-162
Molecular therapy oncolytics 2020 Dec 16;19:149-162
The role of miR-34c-5p/Notch in epithelial-mesenchymal transition (EMT) in endometriosis.
Luo Y, Wang D, Chen S, Yang Q
Cellular signalling 2020 Aug;72:109666
Cellular signalling 2020 Aug;72:109666
Girdin interaction with vimentin induces EMT and promotes the growth and metastasis of pancreatic ductal adenocarcinoma.
Wang W, Chen H, Gao W, Wang S, Wu K, Lu C, Luo X, Li L, Yu C
Oncology reports 2020 Aug;44(2):637-649
Oncology reports 2020 Aug;44(2):637-649
Possible involvement of TGF‑β‑SMAD‑mediated epithelial‑mesenchymal transition in pro‑metastatic property of PAX6.
Jin M, Gao D, Wang R, Sik A, Liu K
Oncology reports 2020 Aug;44(2):555-564
Oncology reports 2020 Aug;44(2):555-564
miR-143 inhibits renal cell carcinoma cells metastatic potential by suppressing ABL2.
Xu B, Wang C, Wang YL, Chen SQ, Wu JP, Zhu WD, Wang CY, Guan H, Guan C, You ZH, Chen M
The Kaohsiung journal of medical sciences 2020 Aug;36(8):592-598
The Kaohsiung journal of medical sciences 2020 Aug;36(8):592-598
Mesenchymal to epithelial transition driven by canine distemper virus infection of canine histiocytic sarcoma cells contributes to a reduced cell motility in vitro.
Armando F, Gambini M, Corradi A, Becker K, Marek K, Pfankuche VM, Mergani AE, Brogden G, de Buhr N, von Köckritz-Blickwede M, Naim HY, Baumgärtner W, Puff C
Journal of cellular and molecular medicine 2020 Aug;24(16):9332-9348
Journal of cellular and molecular medicine 2020 Aug;24(16):9332-9348
Hsa-miR-425-5p promotes tumor growth and metastasis by activating the CTNND1-mediated β-catenin pathway and EMT in colorectal cancer.
Liu D, Zhang H, Cui M, Chen C, Feng Y
Cell cycle (Georgetown, Tex.) 2020 Aug;19(15):1917-1927
Cell cycle (Georgetown, Tex.) 2020 Aug;19(15):1917-1927
circ_0007385 served as competing endogenous RNA for miR-519d-3p to suppress malignant behaviors and cisplatin resistance of non-small cell lung cancer cells.
Ye Y, Zhao L, Li Q, Xi C, Li Y, Li Z
Thoracic cancer 2020 Aug;11(8):2196-2208
Thoracic cancer 2020 Aug;11(8):2196-2208
MicroRNA-378-3p/5p suppresses the migration and invasiveness of oral squamous carcinoma cells by inhibiting KLK4 expression.
Cui Z, Sun S, Liu Q, Zhou X, Gao S, Peng P, Li Q
Biochemistry and cell biology = Biochimie et biologie cellulaire 2020 Apr;98(2):154-163
Biochemistry and cell biology = Biochimie et biologie cellulaire 2020 Apr;98(2):154-163
Stromal fibroblast-derived MFAP5 promotes the invasion and migration of breast cancer cells via Notch1/slug signaling.
Chen Z, Yan X, Li K, Ling Y, Kang H
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2020 Apr;22(4):522-531
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2020 Apr;22(4):522-531
Diminished CD68(+) Cancer-Associated Fibroblast Subset Induces Regulatory T-Cell (Treg) Infiltration and Predicts Poor Prognosis of Oral Squamous Cell Carcinoma Patients.
Zhao X, Ding L, Lu Z, Huang X, Jing Y, Yang Y, Chen S, Hu Q, Ni Y
The American journal of pathology 2020 Apr;190(4):886-899
The American journal of pathology 2020 Apr;190(4):886-899
Novel nortriterpenoids with new skeletons and limonoids from the fruits of Evodia rutaecarpa and their bioactivities.
Shi YS, Xia HM, Wu CH, Li CB, Duan CC, Che C, Zhang XJ, Li HT, Zhang Y, Zhang XF
Fitoterapia 2020 Apr;142:104503
Fitoterapia 2020 Apr;142:104503
The YY1/miR-548t-5p/CXCL11 signaling axis regulates cell proliferation and metastasis in human pancreatic cancer.
Ge WL, Chen Q, Meng LD, Huang XM, Shi GD, Zong QQ, Shen P, Lu YC, Zhang YH, Miao Y, Zhang JJ, Jiang KR
Cell death & disease 2020 Apr 27;11(4):294
Cell death & disease 2020 Apr 27;11(4):294
CCL5 derived from tumor-associated macrophages promotes prostate cancer stem cells and metastasis via activating β-catenin/STAT3 signaling.
Huang R, Wang S, Wang N, Zheng Y, Zhou J, Yang B, Wang X, Zhang J, Guo L, Wang S, Chen Z, Wang Z, Xiang S
Cell death & disease 2020 Apr 16;11(4):234
Cell death & disease 2020 Apr 16;11(4):234
Aligned Biofunctional Electrospun PLGA-LysoGM1 Scaffold for Traumatic Brain Injury Repair.
Tang W, Fang F, Liu K, Huang Z, Li H, Yin Y, Wang J, Wang G, Wei L, Ou Y, Wang Y
ACS biomaterials science & engineering 2020 Apr 13;6(4):2209-2218
ACS biomaterials science & engineering 2020 Apr 13;6(4):2209-2218
MicroRNA-23a-3p Inhibits Mucosal Melanoma Growth and Progression through Targeting Adenylate Cyclase 1 and Attenuating cAMP and MAPK Pathways.
Ma M, Dai J, Tang H, Xu T, Yu S, Si L, Cui C, Sheng X, Chi Z, Mao L, Wu X, Yang L, Yu H, Li S, Lian B, Tang B, Wang X, Yan X, Bai X, Zhou L, Kong Y, Guo J
Theranostics 2019;9(4):945-960
Theranostics 2019;9(4):945-960
Inhibition of SMYD2 suppresses tumor progression by down-regulating microRNA-125b and attenuates multi-drug resistance in renal cell carcinoma.
Yan L, Ding B, Liu H, Zhang Y, Zeng J, Hu J, Yao W, Yu G, An R, Chen Z, Ye Z, Xing J, Xiao K, Wu L, Xu H
Theranostics 2019;9(26):8377-8391
Theranostics 2019;9(26):8377-8391
Sulforaphane Inhibits the Acquisition of Tobacco Smoke-Induced Lung Cancer Stem Cell-Like Properties via the IL-6/ΔNp63α/Notch Axis.
Xie C, Zhu J, Jiang Y, Chen J, Wang X, Geng S, Wu J, Zhong C, Li X, Meng Z
Theranostics 2019;9(16):4827-4840
Theranostics 2019;9(16):4827-4840
Survey of the translation shifts in hepatocellular carcinoma with ribosome profiling.
Zou Q, Xiao Z, Huang R, Wang X, Wang X, Zhao H, Yang X
Theranostics 2019;9(14):4141-4155
Theranostics 2019;9(14):4141-4155
Temporal inhibition of mouse mammary gland cancer metastasis by CORM-A1 and DETA/NO combination therapy.
Porshneva K, Papiernik D, Psurski M, Łupicka-Słowik A, Matkowski R, Ekiert M, Nowak M, Jarosz J, Banach J, Milczarek M, Goszczyński TM, Sieńczyk M, Wietrzyk J
Theranostics 2019;9(13):3918-3939
Theranostics 2019;9(13):3918-3939
SERPIND1 Affects the Malignant Biological Behavior of Epithelial Ovarian Cancer via the PI3K/AKT Pathway: A Mechanistic Study.
Guo Q, Zhu L, Wang C, Wang S, Nie X, Liu J, Liu Q, Hao Y, Li X, Lin B
Frontiers in oncology 2019;9:954
Frontiers in oncology 2019;9:954
CAPE-pNO(2) Inhibited the Growth and Metastasis of Triple-Negative Breast Cancer via the EGFR/STAT3/Akt/E-Cadherin Signaling Pathway.
Huang Q, Li S, Zhang L, Qiao X, Zhang Y, Zhao X, Xiao G, Li Z
Frontiers in oncology 2019;9:461
Frontiers in oncology 2019;9:461
Identification of RE1-Silencing Transcription Factor as a Promoter of Metastasis in Pancreatic Cancer.
Jin H, Liu P, Kong L, Fei X, Gao Y, Wu T, Sun D, Tan X
Frontiers in oncology 2019;9:291
Frontiers in oncology 2019;9:291
Scorpion Venom Analgesic Peptide, BmK AGAP Inhibits Stemness, and Epithelial-Mesenchymal Transition by Down-Regulating PTX3 in Breast Cancer.
Kampo S, Ahmmed B, Zhou T, Owusu L, Anabah TW, Doudou NR, Kuugbee ED, Cui Y, Lu Z, Yan Q, Wen QP
Frontiers in oncology 2019;9:21
Frontiers in oncology 2019;9:21
LncRNA ZFAS1 promotes proliferation and migration and inhibits apoptosis in nasopharyngeal carcinoma via the PI3K/AKT pathway in vitro.
Wang X, Jin Q, Wang X, Chen W, Cai Z
Cancer biomarkers : section A of Disease markers 2019;26(2):171-182
Cancer biomarkers : section A of Disease markers 2019;26(2):171-182
The long noncoding RNA LINC00483 promotes lung adenocarcinoma progression by sponging miR-204-3p.
Yang S, Liu T, Sun Y, Liang X
Cellular & molecular biology letters 2019;24:70
Cellular & molecular biology letters 2019;24:70
Betulinic Acid Suppresses Breast Cancer Metastasis by Targeting GRP78-Mediated Glycolysis and ER Stress Apoptotic Pathway.
Zheng Y, Liu P, Wang N, Wang S, Yang B, Li M, Chen J, Situ H, Xie M, Lin Y, Wang Z
Oxidative medicine and cellular longevity 2019;2019:8781690
Oxidative medicine and cellular longevity 2019;2019:8781690
Ferritinophagic Flux Activation in CT26 Cells Contributed to EMT Inhibition Induced by a Novel Iron Chelator, DpdtpA.
Sun Y, Li C, Feng J, Li Y, Zhai X, Zhang L, Li C
Oxidative medicine and cellular longevity 2019;2019:8753413
Oxidative medicine and cellular longevity 2019;2019:8753413
2-Methoxy-5((3,4,5-trimethosyphenyl)seleninyl) phenol reverses EGF-induced cell migration and invasion through down-regulation of MDM2 in breast cancer cell lines.
Zheng D, Chang X, Liu Y, Xu J, Gou W, Li Z, Zuo D, Zhang W, Wu Y
Cancer biology & therapy 2019;20(4):513-523
Cancer biology & therapy 2019;20(4):513-523
FBXO22 Suppresses Metastasis in Human Renal Cell Carcinoma via Inhibiting MMP-9-Mediated Migration and Invasion and VEGF-Mediated Angiogenesis.
Guo F, Liu J, Han X, Zhang X, Lin T, Wang Y, Bai J, Han J
International journal of biological sciences 2019;15(3):647-656
International journal of biological sciences 2019;15(3):647-656
CLK3 Is A Direct Target Of miR-144 And Contributes To Aggressive Progression In Hepatocellular Carcinoma.
Li H, Cui X, Hu Q, Chen X, Zhou P
OncoTargets and therapy 2019;12:9201-9213
OncoTargets and therapy 2019;12:9201-9213
Exosomal Tenascin-c induces proliferation and invasion of pancreatic cancer cells by WNT signaling.
Qian S, Tan X, Liu X, Liu P, Wu Y
OncoTargets and therapy 2019;12:3197-3205
OncoTargets and therapy 2019;12:3197-3205
High expression of long non-coding RNA NNT-AS1 facilitates progression of cholangiocarcinoma through promoting epithelial-mesenchymal transition.
Gu Y, Li C, Xiao L, Li J, Pei H, Xu D, Jiang Y, Zhang X, Zhang L, Li K, Zhu Z, Chen X
American journal of translational research 2019;11(9):5438-5456
American journal of translational research 2019;11(9):5438-5456
Long noncoding RNA CASC15 predicts unfavorable prognosis and exerts oncogenic functions in non-small cell lung cancer.
Li M, Chen Y, Zhu J, Gao Z, Wang T, Zhou P
American journal of translational research 2019;11(7):4303-4314
American journal of translational research 2019;11(7):4303-4314
Lipase member H is a downstream molecular target of hypoxia inducible factor-1α and promotes papillary thyroid carcinoma cell migration in BCPAP and KTC-1 cell lines.
Li Y, Zhou X, Zhang Q, Chen E, Sun Y, Ye D, Wang O, Zhang X, Lyu J
Cancer management and research 2019;11:931-941
Cancer management and research 2019;11:931-941
12-lipoxygenase promotes tumor progress by TGF-β1-mediated epithelial to mesenchymal transition and predicts poor prognosis in esophageal squamous cell carcinoma.
Qu Y, Wen Z, Mi S, Chen P, Wang J, Jia Y, Cheng Y
Cancer management and research 2019;11:8303-8313
Cancer management and research 2019;11:8303-8313
Overexpressed PKMYT1 promotes tumor progression and associates with poor survival in esophageal squamous cell carcinoma.
Zhang Q, Zhao X, Zhang C, Wang W, Li F, Liu D, Wu K, Zhu D, Liu S, Shen C, Yuan X, Zhang K, Yang Y, Zhang Y, Zhao S
Cancer management and research 2019;11:7813-7824
Cancer management and research 2019;11:7813-7824
The oncogenic role of GNL3 in the progression and metastasis of osteosarcoma.
Li T, Li L, Wu X, Tian K, Wang Y
Cancer management and research 2019;11:2179-2188
Cancer management and research 2019;11:2179-2188
Lyn Kinase Promotes the Proliferation of Malignant Melanoma Cells through Inhibition of Apoptosis and Autophagy via the PI3K/Akt Signaling Pathway.
Zhang Q, Meng X, Qin G, Xue X, Dang N
Journal of Cancer 2019;10(5):1197-1208
Journal of Cancer 2019;10(5):1197-1208
RUFY3 Predicts Poor Prognosis and Promotes Metastasis through Epithelial-mesenchymal Transition in Lung Adenocarcinoma.
Men W, Li W, Li Y, Zhao J, Qu X, Li P, Gong S
Journal of Cancer 2019;10(25):6278-6285
Journal of Cancer 2019;10(25):6278-6285
Dysregulation of MiR-519d Affects Oral Squamous Cell Carcinoma Invasion and Metastasis by Targeting MMP3.
Jin Y, Li Y, Wang X, Yang Y
Journal of Cancer 2019;10(12):2720-2734
Journal of Cancer 2019;10(12):2720-2734
Small Nucleolar RNA 71A Promotes Lung Cancer Cell Proliferation, Migration and Invasion via MAPK/ERK Pathway.
Tang G, Zeng Z, Sun W, Li S, You C, Tang F, Peng S, Ma S, Luo Y, Xu J, Tian X, Zhang N, Gong Y, Xie C
Journal of Cancer 2019;10(10):2261-2275
Journal of Cancer 2019;10(10):2261-2275
Activation of CXCL6/CXCR1/2 Axis Promotes the Growth and Metastasis of Osteosarcoma Cells in vitro and in vivo.
Liu G, An L, Zhang H, Du P, Sheng Y
Frontiers in pharmacology 2019;10:307
Frontiers in pharmacology 2019;10:307
Knockdown of SP1/Syncytin1 axis inhibits the proliferation and metastasis through the AKT and ERK1/2 signaling pathways in non-small cell lung cancer.
Li X, Fu Y, Xia X, Zhang X, Xiao K, Zhuang X, Zhang Y
Cancer medicine 2019 Sep;8(12):5750-5759
Cancer medicine 2019 Sep;8(12):5750-5759
Fluorene-9-bisphenol inhibits epithelial-mesenchymal transition of human endometrial cancer Ishikawa cells by repressing TGF-β signaling pathway.
Wang L, Zhuang T, Li F, Wei W
Environmental science and pollution research international 2019 Sep;26(26):27407-27413
Environmental science and pollution research international 2019 Sep;26(26):27407-27413
Long non-coding RNA linc00645 promotes TGF-β-induced epithelial-mesenchymal transition by regulating miR-205-3p-ZEB1 axis in glioma.
Li C, Zheng H, Hou W, Bao H, Xiong J, Che W, Gu Y, Sun H, Liang P
Cell death & disease 2019 Sep 26;10(10):717
Cell death & disease 2019 Sep 26;10(10):717
Sulforaphane inhibits epithelial-mesenchymal transition by activating extracellular signal-regulated kinase 5 in lung cancer cells.
Chen Y, Chen JQ, Ge MM, Zhang Q, Wang XQ, Zhu JY, Xie CF, Li XT, Zhong CY, Han HY
The Journal of nutritional biochemistry 2019 Oct;72:108219
The Journal of nutritional biochemistry 2019 Oct;72:108219
Macrophage migration inhibitory factor promotes the invasion and metastasis of oral squamous cell carcinoma through matrix metalloprotein-2/9.
Wang SS, Zheng M, Pang X, Zhang M, Yu XH, Wu JB, Gao XL, Wu JS, Yang X, Tang YJ, Tang YL, Liang XH
Molecular carcinogenesis 2019 Oct;58(10):1809-1821
Molecular carcinogenesis 2019 Oct;58(10):1809-1821
A novel tetravalent bispecific antibody targeting programmed death 1 and tyrosine-protein kinase Met for treatment of gastric cancer.
Hou W, Yuan Q, Yuan X, Wang Y, Mo W, Wang H, Yu M
Investigational new drugs 2019 Oct;37(5):876-889
Investigational new drugs 2019 Oct;37(5):876-889
Yes-associated protein (YAP) predicts poor prognosis and regulates progression of esophageal squamous cell cancer through epithelial-mesenchymal transition.
Qu Y, Zhang L, Wang J, Chen P, Jia Y, Wang C, Yang W, Wen Z, Song Q, Tan B, Cheng Y
Experimental and therapeutic medicine 2019 Oct;18(4):2993-3001
Experimental and therapeutic medicine 2019 Oct;18(4):2993-3001
CircWHSC1 promotes ovarian cancer progression by regulating MUC1 and hTERT through sponging miR-145 and miR-1182.
Zong ZH, Du YP, Guan X, Chen S, Zhao Y
Journal of experimental & clinical cancer research : CR 2019 Oct 30;38(1):437
Journal of experimental & clinical cancer research : CR 2019 Oct 30;38(1):437
Curcumin mitigates the epithelial-to-mesenchymal transition in biliary epithelial cells through upregulating CD109 expression.
Fan J, Wang Q, Zhang Z, Sun L
Drug development research 2019 Nov;80(7):992-999
Drug development research 2019 Nov;80(7):992-999
Huangqi-Fangfeng protects against allergic airway remodeling through inhibiting epithelial-mesenchymal transition process in mice via regulating epithelial derived TGF-β1.
Yao L, Wang S, Wei P, Bao K, Yuan W, Wang X, Zheng J, Hong M
Phytomedicine : international journal of phytotherapy and phytopharmacology 2019 Nov;64:153076
Phytomedicine : international journal of phytotherapy and phytopharmacology 2019 Nov;64:153076
Knockdown of FAM64A suppresses proliferation and migration of breast cancer cells.
Yao Z, Zheng X, Lu S, He Z, Miao Y, Huang H, Chu X, Cai C, Zou F
Breast cancer (Tokyo, Japan) 2019 Nov;26(6):835-845
Breast cancer (Tokyo, Japan) 2019 Nov;26(6):835-845
The miR-27a-3p/USP25 axis participates in the pathogenesis of recurrent miscarriage by inhibiting trophoblast migration and invasion.
Ding J, Cheng Y, Zhang Y, Liao S, Yin T, Yang J
Journal of cellular physiology 2019 Nov;234(11):19951-19963
Journal of cellular physiology 2019 Nov;234(11):19951-19963
Downregulation of Rab23 inhibits proliferation, invasion, and metastasis of human ovarian cancer.
Gao L, Zheng M, Guo Q, Nie X, Li X, Hao Y, Liu J, Zhu L, Lin B
The international journal of biochemistry & cell biology 2019 Nov;116:105617
The international journal of biochemistry & cell biology 2019 Nov;116:105617
PITPNA-AS1 abrogates the inhibition of miR-876-5p on WNT5A to facilitate hepatocellular carcinoma progression.
Sun J, Zhang Y, Li B, Dong Y, Sun C, Zhang F, Jin L, Chen D, Wang W
Cell death & disease 2019 Nov 7;10(11):844
Cell death & disease 2019 Nov 7;10(11):844
STRA6 exerts oncogenic role in gastric tumorigenesis by acting as a crucial target of miR-873.
Lin L, Xiao J, Shi L, Chen W, Ge Y, Jiang M, Li Z, Fan H, Yang L, Xu Z
Journal of experimental & clinical cancer research : CR 2019 Nov 6;38(1):452
Journal of experimental & clinical cancer research : CR 2019 Nov 6;38(1):452
Sinulariolide Inhibits Gastric Cancer Cell Migration and Invasion through Downregulation of the EMT Process and Suppression of FAK/PI3K/AKT/mTOR and MAPKs Signaling Pathways.
Wu YJ, Lin SH, Din ZH, Su JH, Liu CI
Marine drugs 2019 Nov 27;17(12)
Marine drugs 2019 Nov 27;17(12)
Graphene oxide substrates with N-cadherin stimulates neuronal growth and intracellular transport.
Qin EC, Kandel ME, Liamas E, Shah TB, Kim C, Kaufman CD, Zhang ZJ, Popescu G, Gillette MU, Leckband DE, Kong H
Acta biomaterialia 2019 May;90:412-423
Acta biomaterialia 2019 May;90:412-423
Hypoxia promotes vasculogenic mimicry formation by vascular endothelial growth factor A mediating epithelial-mesenchymal transition in salivary adenoid cystic carcinoma.
Wang HF, Wang SS, Zheng M, Dai LL, Wang K, Gao XL, Cao MX, Yu XH, Pang X, Zhang M, Wu JB, Wu JS, Yang X, Tang YJ, Chen Y, Tang YL, Liang XH
Cell proliferation 2019 May;52(3):e12600
Cell proliferation 2019 May;52(3):e12600
RPS7 promotes cell migration through targeting epithelial-mesenchymal transition in prostate cancer.
Wen Y, An Z, Qiao B, Zhang C, Zhang Z
Urologic oncology 2019 May;37(5):297.e1-297.e7
Urologic oncology 2019 May;37(5):297.e1-297.e7
Upregulation of lncRNA DGCR5 correlates with better prognosis and inhibits bladder cancer progression via transcriptionally facilitating P21 expression.
Fang C, He W, Xu T, Dai J, Xu L, Sun F
Journal of cellular physiology 2019 May;234(5):6254-6262
Journal of cellular physiology 2019 May;234(5):6254-6262
SSRP1 promotes colorectal cancer progression and is negatively regulated by miR-28-5p.
Wu W, He K, Guo Q, Chen J, Zhang M, Huang K, Yang D, Wu L, Deng Y, Luo X, Yu H, Ding Q, Xiang G
Journal of cellular and molecular medicine 2019 May;23(5):3118-3129
Journal of cellular and molecular medicine 2019 May;23(5):3118-3129
Upregulated forkhead-box A3 elevates the expression of forkhead-box A1 and forkhead-box A2 to promote metastasis in esophageal cancer.
Chen B, Yu J, Lu L, Dong F, Zhou F, Tao X, Sun E
Oncology letters 2019 May;17(5):4351-4360
Oncology letters 2019 May;17(5):4351-4360
miR-340-FHL2 axis inhibits cell growth and metastasis in ovarian cancer.
Huang Z, Li Q, Luo K, Zhang Q, Geng J, Zhou X, Xu Y, Qian M, Zhang JA, Ji L, Wu J
Cell death & disease 2019 May 8;10(5):372
Cell death & disease 2019 May 8;10(5):372
M2 macrophages promote NSCLC metastasis by upregulating CRYAB.
Guo Z, Song J, Hao J, Zhao H, Du X, Li E, Kuang Y, Yang F, Wang W, Deng J, Wang Q
Cell death & disease 2019 May 16;10(6):377
Cell death & disease 2019 May 16;10(6):377
Wnt7a predicts poor prognosis, and contributes to growth and metastasis in tongue squamous cell carcinoma.
Jia B, Qiu X, Chu H, Sun X, Xu S, Zhao X, Zhao J
Oncology reports 2019 Mar;41(3):1749-1758
Oncology reports 2019 Mar;41(3):1749-1758
LncRNA MIR22HG inhibits growth, migration and invasion through regulating the miR-10a-5p/NCOR2 axis in hepatocellular carcinoma cells.
Wu Y, Zhou Y, Huan L, Xu L, Shen M, Huang S, Liang L
Cancer science 2019 Mar;110(3):973-984
Cancer science 2019 Mar;110(3):973-984
Nuciferine inhibits the progression of glioblastoma by suppressing the SOX2-AKT/STAT3-Slug signaling pathway.
Li Z, Chen Y, An T, Liu P, Zhu J, Yang H, Zhang W, Dong T, Jiang J, Zhang Y, Jiang M, Yang X
Journal of experimental & clinical cancer research : CR 2019 Mar 29;38(1):139
Journal of experimental & clinical cancer research : CR 2019 Mar 29;38(1):139
The Attenuation of Trophoblast Invasion Caused by the Downregulation of EZH2 Is Involved in the Pathogenesis of Human Recurrent Miscarriage.
Lv S, Wang N, Lv H, Yang J, Liu J, Li WP, Zhang C, Chen ZJ
Molecular therapy. Nucleic acids 2019 Mar 1;14:377-387
Molecular therapy. Nucleic acids 2019 Mar 1;14:377-387
AKR1B10 (Aldo-keto reductase family 1 B10) promotes brain metastasis of lung cancer cells in a multi-organ microfluidic chip model.
Liu W, Song J, Du X, Zhou Y, Li Y, Li R, Lyu L, He Y, Hao J, Ben J, Wang W, Shi H, Wang Q
Acta biomaterialia 2019 Jun;91:195-208
Acta biomaterialia 2019 Jun;91:195-208
Tacalcitol increases the sensitivity of colorectal cancer cells to 5-fluorouracil by downregulating the thymidylate synthase.
Milczarek M, Rossowska J, Klopotowska D, Stachowicz M, Kutner A, Wietrzyk J
The Journal of steroid biochemistry and molecular biology 2019 Jun;190:139-151
The Journal of steroid biochemistry and molecular biology 2019 Jun;190:139-151
Bronchial epithelial cell extracellular vesicles ameliorate epithelial-mesenchymal transition in COPD pathogenesis by alleviating M2 macrophage polarization.
He S, Chen D, Hu M, Zhang L, Liu C, Traini D, Grau GE, Zeng Z, Lu J, Zhou G, Xie L, Sun S
Nanomedicine : nanotechnology, biology, and medicine 2019 Jun;18:259-271
Nanomedicine : nanotechnology, biology, and medicine 2019 Jun;18:259-271
Platelets promote invasion and induce epithelial to mesenchymal transition in ovarian cancer cells by TGF-β signaling pathway.
Guo Y, Cui W, Pei Y, Xu D
Gynecologic oncology 2019 Jun;153(3):639-650
Gynecologic oncology 2019 Jun;153(3):639-650
circ-CSPP1 promotes proliferation, invasion and migration of ovarian cancer cells by acting as a miR-1236-3p sponge.
Li QH, Liu Y, Chen S, Zong ZH, Du YP, Sheng XJ, Zhao Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jun;114:108832
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jun;114:108832
Calcium-Activated Chloride Channel A4 (CLCA4) Plays Inhibitory Roles in Invasion and Migration Through Suppressing Epithelial-Mesenchymal Transition via PI3K/AKT Signaling in Colorectal Cancer.
Chen H, Liu Y, Jiang CJ, Chen YM, Li H, Liu QA
Medical science monitor : international medical journal of experimental and clinical research 2019 Jun 5;25:4176-4185
Medical science monitor : international medical journal of experimental and clinical research 2019 Jun 5;25:4176-4185
Effects of MCRS1 on proliferation, migration, invasion, and epithelial mesenchymal transition of gastric cancer cells by interacting with Pkmyt1 protein kinase.
Wang XM, Li QY, Ren LL, Liu YM, Wang TS, Mu TC, Fu S, Liu C, Xiao JY
Cellular signalling 2019 Jul;59:171-181
Cellular signalling 2019 Jul;59:171-181
Mesenchymal stem cell-secreted factors delayed spermatogenesis injuries induced by busulfan involving intercellular adhesion molecule regulation.
Cai YT, Xiong CL, Shen SL, Rao JP, Liu TS, Qiu F
Andrologia 2019 Jul;51(6):e13285
Andrologia 2019 Jul;51(6):e13285
The potential role of pregnancy-associated plasma protein-A2 in angiogenesis and development of preeclampsia.
Chen X, Chen K, Feng Y, Ren C, Li W, Xiao J, Fan L, Beejadhursing R, Xi L, Chen S
Hypertension research : official journal of the Japanese Society of Hypertension 2019 Jul;42(7):970-980
Hypertension research : official journal of the Japanese Society of Hypertension 2019 Jul;42(7):970-980
NAV2 facilitates invasion of cutaneous melanoma cells by targeting SNAI2 through the GSK-3β/β-catenin pathway.
Hu W, Li X, Cheng R, Ke J, Liu Y, Ma M, Cao Y, Liu D
Archives of dermatological research 2019 Jul;311(5):399-410
Archives of dermatological research 2019 Jul;311(5):399-410
Exogenous regucalcin negatively regulates the progression of cervical adenocarcinoma.
Li X, Huang Y, Guo S, Xie M, Bin X, Shi M, Chen A, Chen S, Wu F, Hu Q, Zhou S
Oncology letters 2019 Jul;18(1):609-616
Oncology letters 2019 Jul;18(1):609-616
MicroRNA-23a promotes colorectal cancer cell migration and proliferation by targeting at MARK1.
Tang X, Yang M, Wang Z, Wu X, Wang D
Acta biochimica et biophysica Sinica 2019 Jul 10;51(7):661-668
Acta biochimica et biophysica Sinica 2019 Jul 10;51(7):661-668
Downregulation of DAPK1 promotes the stemness of cancer stem cells and EMT process by activating ZEB1 in colorectal cancer.
Yuan W, Ji J, Shu Y, Chen J, Liu S, Wu L, Zhou Z, Liu Z, Tang Q, Zhang X, Shu X
Journal of molecular medicine (Berlin, Germany) 2019 Jan;97(1):89-102
Journal of molecular medicine (Berlin, Germany) 2019 Jan;97(1):89-102
Dual regulatory role of CCNA2 in modulating CDK6 and MET-mediated cell-cycle pathway and EMT progression is blocked by miR-381-3p in bladder cancer.
Li J, Ying Y, Xie H, Jin K, Yan H, Wang S, Xu M, Xu X, Wang X, Yang K, Zheng X, Xie L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jan;33(1):1374-1388
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jan;33(1):1374-1388
Chromium(VI) promotes cell migration through targeting epithelial-mesenchymal transition in prostate cancer.
Zhang C, Cai K, Feng Q, Xu Y, Zhang Z
Toxicology letters 2019 Jan;300:10-17
Toxicology letters 2019 Jan;300:10-17
Opa interacting protein 5 promotes metastasis of nasopharyngeal carcinoma cells by promoting EMT via modulation of JAK2/STAT3 signal.
Zheng YQ, Cui YR, Yang S, Wang YP, Qiu YJ, Hu WL
European review for medical and pharmacological sciences 2019 Jan;23(2):613-621
European review for medical and pharmacological sciences 2019 Jan;23(2):613-621
FOXC1 silencing inhibits the epithelial‑to‑mesenchymal transition of glioma cells: Involvement of β‑catenin signaling.
Cao Q, Wang X, Shi Y, Zhang M, Yang J, Dong M, Mi Y, Zhang Z, Liu K, Jiang L, Wang N, Wang P
Molecular medicine reports 2019 Jan;19(1):251-261
Molecular medicine reports 2019 Jan;19(1):251-261
Tobacco smoke induced hepatic cancer stem cell-like properties through IL-33/p38 pathway.
Xie C, Zhu J, Wang X, Chen J, Geng S, Wu J, Zhong C, Li X
Journal of experimental & clinical cancer research : CR 2019 Jan 28;38(1):39
Journal of experimental & clinical cancer research : CR 2019 Jan 28;38(1):39
Long noncoding FOXD2-AS1 is activated by CREB1 and promotes cell proliferation and metastasis in glioma by sponging miR-185 through targeting AKT1.
Dong H, Cao W, Xue J
Biochemical and biophysical research communications 2019 Jan 22;508(4):1074-1081
Biochemical and biophysical research communications 2019 Jan 22;508(4):1074-1081
Inhibition of ATP citrate lyase (ACLY) protects airway epithelia from PM(2.5)-induced epithelial-mesenchymal transition.
Fu Y, Lu R, Cui J, Sun H, Yang H, Meng Q, Wu S, Aschner M, Li X, Chen R
Ecotoxicology and environmental safety 2019 Jan 15;167:309-316
Ecotoxicology and environmental safety 2019 Jan 15;167:309-316
ARHGEF10L contributes to liver tumorigenesis through RhoA-ROCK1 signaling and the epithelial-mesenchymal transition.
Tang J, Liu C, Xu B, Wang D, Ma Z, Chang X
Experimental cell research 2019 Jan 1;374(1):46-68
Experimental cell research 2019 Jan 1;374(1):46-68
LincK contributes to breast tumorigenesis by promoting proliferation and epithelial-to-mesenchymal transition.
Li J, Hao Y, Mao W, Xue X, Xu P, Liu L, Yuan J, Zhang D, Li N, Chen H, Zhao L, Sun Z, Luo J, Chen R, Zhao RC
Journal of hematology & oncology 2019 Feb 22;12(1):19
Journal of hematology & oncology 2019 Feb 22;12(1):19
Zoledronic acid inhibits the growth of cancer stem cell derived from cervical cancer cell by attenuating their stemness phenotype and inducing apoptosis and cell cycle arrest through the Erk1/2 and Akt pathways.
Wang L, Liu Y, Zhou Y, Wang J, Tu L, Sun Z, Wang X, Luo F
Journal of experimental & clinical cancer research : CR 2019 Feb 21;38(1):93
Journal of experimental & clinical cancer research : CR 2019 Feb 21;38(1):93
P53-induced miR-1249 inhibits tumor growth, metastasis, and angiogenesis by targeting VEGFA and HMGA2.
Chen X, Zeng K, Xu M, Liu X, Hu X, Xu T, He B, Pan Y, Sun H, Wang S
Cell death & disease 2019 Feb 12;10(2):131
Cell death & disease 2019 Feb 12;10(2):131
Lipoprotein receptor-related protein 6 is required to maintain intercalated disk integrity.
Wang X, Zou Y, Li Y, Chen Z, Yin C, Wang Y, Zhang L, Wu J, Yang C, Zhang G, Zou Y, Gong H
Genes to cells : devoted to molecular & cellular mechanisms 2019 Dec;24(12):789-800
Genes to cells : devoted to molecular & cellular mechanisms 2019 Dec;24(12):789-800
Knockdown of periostin attenuates 5/6 nephrectomy-induced intrarenal renin-angiotensin system activation, fibrosis, and inflammation in rats.
Bian X, Bai Y, Su X, Zhao G, Sun G, Li D
Journal of cellular physiology 2019 Dec;234(12):22857-22873
Journal of cellular physiology 2019 Dec;234(12):22857-22873
Downregulation of HDAC3 by ginsenoside Rg3 inhibits epithelial-mesenchymal transition of cutaneous squamous cell carcinoma through c-Jun acetylation.
Zhang L, Shan X, Chen Q, Xu D, Fan X, Yu M, Yan Q, Liu J
Journal of cellular physiology 2019 Dec;234(12):22207-22219
Journal of cellular physiology 2019 Dec;234(12):22207-22219
miR-451a inhibits cancer growth, epithelial-mesenchymal transition and induces apoptosis in papillary thyroid cancer by targeting PSMB8.
Fan X, Zhao Y
Journal of cellular and molecular medicine 2019 Dec;23(12):8067-8075
Journal of cellular and molecular medicine 2019 Dec;23(12):8067-8075
Targeting amphiregulin (AREG) derived from senescent stromal cells diminishes cancer resistance and averts programmed cell death 1 ligand (PD-L1)-mediated immunosuppression.
Xu Q, Long Q, Zhu D, Fu D, Zhang B, Han L, Qian M, Guo J, Xu J, Cao L, Chin YE, Coppé JP, Lam EW, Campisi J, Sun Y
Aging cell 2019 Dec;18(6):e13027
Aging cell 2019 Dec;18(6):e13027
Protective effects of betaine on diabetic induced disruption of the male mice blood-testis barrier by regulating oxidative stress-mediated p38 MAPK pathways.
Jiang YP, Yang JM, Ye RJ, Liu N, Zhang WJ, Ma L, Zheng P, Niu JG, Liu P, Yu JQ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109474
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109474
Silencing TTK expression inhibits the proliferation and progression of prostate cancer.
Chen S, Wang J, Wang L, Peng H, Xiao L, Li C, Lin D, Yang K
Experimental cell research 2019 Dec 1;385(1):111669
Experimental cell research 2019 Dec 1;385(1):111669
Long noncoding RNA SOX21-AS1 promotes cervical cancer progression by competitively sponging miR-7/VDAC1.
Zhang X, Zhao X, Li Y, Zhou Y, Zhang Z
Journal of cellular physiology 2019 Aug;234(10):17494-17504
Journal of cellular physiology 2019 Aug;234(10):17494-17504
miR-205-5p regulates epithelial-mesenchymal transition by targeting PTEN via PI3K/AKT signaling pathway in cisplatin-resistant nasopharyngeal carcinoma cells.
Zhang P, Lu X, Shi Z, Li X, Zhang Y, Zhao S, Liu H
Gene 2019 Aug 20;710:103-113
Gene 2019 Aug 20;710:103-113
miR-504 suppresses mesenchymal phenotype of glioblastoma by directly targeting the FZD7-mediated Wnt-β-catenin pathway.
Liu Q, Guan Y, Li Z, Wang Y, Liu Y, Cui R, Wang Y
Journal of experimental & clinical cancer research : CR 2019 Aug 16;38(1):358
Journal of experimental & clinical cancer research : CR 2019 Aug 16;38(1):358
Down-regulation of lncRNA-ATB inhibits epithelial-mesenchymal transition of breast cancer cells by increasing miR-141-3p expression.
Zhang Y, Li J, Jia S, Wang Y, Kang Y, Zhang W
Biochemistry and cell biology = Biochimie et biologie cellulaire 2019 Apr;97(2):193-200
Biochemistry and cell biology = Biochimie et biologie cellulaire 2019 Apr;97(2):193-200
LncRNA H19 interacted with miR-130a-3p and miR-17-5p to modify radio-resistance and chemo-sensitivity of cardiac carcinoma cells.
Jia J, Zhang X, Zhan D, Li J, Li Z, Li H, Qian J
Cancer medicine 2019 Apr;8(4):1604-1618
Cancer medicine 2019 Apr;8(4):1604-1618
A mechanism of regucalcin knock-down in the promotion of proliferation and movement of human cervical cancer HeLa cells.
Li X, Huang Y, Wang P, Song W, Yao Q, Hu Q, Zhou S
Translational cancer research 2019 Apr;8(2):402-409
Translational cancer research 2019 Apr;8(2):402-409
Dependence of artesunate on long noncoding RNA-RP11 to inhibit epithelial-mesenchymal transition of hepatocellular carcinoma.
Jing W, Dong H, Min M, Runpeng Z, Xuewei X, Ru C, Yingru X, Shengfa N, Baoxian T, Jinbo Y, Weidong H, Rongbo Z
Journal of cellular biochemistry 2019 Apr;120(4):6026-6034
Journal of cellular biochemistry 2019 Apr;120(4):6026-6034
Bone marrow mesenchymal stem cells suppress growth and promote the apoptosis of glioma U251 cells through downregulation of the PI3K/AKT signaling pathway.
Lu L, Chen G, Yang J, Ma Z, Yang Y, Hu Y, Lu Y, Cao Z, Wang Y, Wang X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Apr;112:108625
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Apr;112:108625
Network-pharmacology-based identification of caveolin-1 as a key target of Oldenlandia diffusa to suppress breast cancer metastasis.
Yang B, Wang N, Wang S, Li X, Zheng Y, Li M, Song J, Zhang F, Mei W, Lin Y, Wang Z
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Apr;112:108607
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Apr;112:108607
GTSE1 is involved in breast cancer progression in p53 mutation-dependent manner.
Lin F, Xie YJ, Zhang XK, Huang TJ, Xu HF, Mei Y, Liang H, Hu H, Lin ST, Luo FF, Lang YH, Peng LX, Qian CN, Huang BJ
Journal of experimental & clinical cancer research : CR 2019 Apr 8;38(1):152
Journal of experimental & clinical cancer research : CR 2019 Apr 8;38(1):152
The PAX6-ZEB2 axis promotes metastasis and cisplatin resistance in non-small cell lung cancer through PI3K/AKT signaling.
Wu DM, Zhang T, Liu YB, Deng SH, Han R, Liu T, Li J, Xu Y
Cell death & disease 2019 Apr 25;10(5):349
Cell death & disease 2019 Apr 25;10(5):349
Circular RNA circTADA2A promotes osteosarcoma progression and metastasis by sponging miR-203a-3p and regulating CREB3 expression.
Wu Y, Xie Z, Chen J, Chen J, Ni W, Ma Y, Huang K, Wang G, Wang J, Ma J, Shen S, Fan S
Molecular cancer 2019 Apr 2;18(1):73
Molecular cancer 2019 Apr 2;18(1):73
S100A4-MYH9 Axis Promote Migration and Invasion of Gastric Cancer Cells by Inducing TGF-β-Mediated Epithelial-Mesenchymal Transition.
Li F, Shi J, Xu Z, Yao X, Mou T, Yu J, Liu H, Li G
Journal of Cancer 2018;9(21):3839-3849
Journal of Cancer 2018;9(21):3839-3849
Tip60 Suppresses Cholangiocarcinoma Proliferation and Metastasis via PI3k-AKT.
Zhang Y, Ji G, Han S, Shao Z, Lu Z, Huo L, Zhang J, Yang R, Feng Q, Shen H, Wang H, Li X
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(2):612-628
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(2):612-628
The Natural Compound Myricetin Effectively Represses the Malignant Progression of Prostate Cancer by Inhibiting PIM1 and Disrupting the PIM1/CXCR4 Interaction.
Ye C, Zhang C, Huang H, Yang B, Xiao G, Kong D, Tian Q, Song Q, Song Y, Tan H, Wang Y, Zhou T, Zi X, Sun Y
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;48(3):1230-1244
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;48(3):1230-1244
MiR-598 Suppresses Invasion and Migration by Negative Regulation of Derlin-1 and Epithelial-Mesenchymal Transition in Non-Small Cell Lung Cancer.
Yang F, Wei K, Qin Z, Liu W, Shao C, Wang C, Ma L, Xie M, Shu Y, Shen H
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(1):245-256
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(1):245-256
C/D-Box Snord105b Promotes Tumorigenesis in Gastric Cancer via ALDOA/C-Myc Pathway.
Zhang C, Zhao LM, Wu H, Tian G, Dai SL, Zhao RY, Shan BE
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;45(6):2471-2482
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;45(6):2471-2482
Silencing Formin-like 2 inhibits growth and metastasis of gastric cancer cells through suppressing internalization of integrins.
Zhong B, Wang K, Xu H, Kong F
Cancer cell international 2018;18:79
Cancer cell international 2018;18:79
Tumor-associated macrophages derived CCL18 promotes metastasis in squamous cell carcinoma of the head and neck.
She L, Qin Y, Wang J, Liu C, Zhu G, Li G, Wei M, Chen C, Liu G, Zhang D, Chen X, Wang Y, Qiu Y, Tian Y, Zhang X, Liu Y, Huang D
Cancer cell international 2018;18:120
Cancer cell international 2018;18:120
Overexpression of TEAD4 correlates with poor prognosis of glioma and promotes cell invasion.
Xu A, Wang X, Zeng Y, Zhou M, Yi R, Wu Z, Lin J, Song Y
International journal of clinical and experimental pathology 2018;11(10):4827-4835
International journal of clinical and experimental pathology 2018;11(10):4827-4835
KIAA1199 overexpression is associated with abnormal expression of EMT markers and is a novel independent prognostic biomarker for hepatocellular carcinoma.
Jiang Z, Zhai X, Shi B, Luo D, Jin B
OncoTargets and therapy 2018;11:8341-8348
OncoTargets and therapy 2018;11:8341-8348
Contribution of dysregulated circRNA_100876 to proliferation and metastasis of esophageal squamous cell carcinoma.
Cao S, Chen G, Yan L, Li L, Huang X
OncoTargets and therapy 2018;11:7385-7394
OncoTargets and therapy 2018;11:7385-7394
Effect of simvastatin and microRNA-21 inhibitor on metastasis and progression of human salivary adenoid cystic carcinoma.
Wang C, Li T, Yan F, Cai W, Zheng J, Jiang X, Sun J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Sep;105:1054-1061
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Sep;105:1054-1061
SNORA42 enhances prostate cancer cell viability, migration and EMT and is correlated with prostate cancer poor prognosis.
Yi C, Wan X, Zhang Y, Fu F, Zhao C, Qin R, Wu H, Li Y, Huang Y
The international journal of biochemistry & cell biology 2018 Sep;102:138-150
The international journal of biochemistry & cell biology 2018 Sep;102:138-150
Melittin-induced long non-coding RNA NONHSAT105177 inhibits proliferation and migration of pancreatic ductal adenocarcinoma.
Wang X, Li H, Lu X, Wen C, Huo Z, Shi M, Tang X, Chen H, Peng C, Fang Y, Deng X, Shen B
Cell death & disease 2018 Sep 20;9(10):940
Cell death & disease 2018 Sep 20;9(10):940
TGF-β-mediated exosomal lnc-MMP2-2 regulates migration and invasion of lung cancer cells to the vasculature by promoting MMP2 expression.
Wu DM, Deng SH, Liu T, Han R, Zhang T, Xu Y
Cancer medicine 2018 Oct;7(10):5118-5129
Cancer medicine 2018 Oct;7(10):5118-5129
Selenium (Na(2)SeO(3)) Upregulates Expression of Immune Genes and Blood-Testis Barrier Constituent Proteins of Bovine Sertoli Cell In Vitro.
Adegoke EO, Wang X, Wang H, Wang C, Zhang H, Zhang G
Biological trace element research 2018 Oct;185(2):332-343
Biological trace element research 2018 Oct;185(2):332-343
Low-Dose Radiation Enhanced Inhibition of Breast Tumor Xenograft and Reduced Myocardial Injury Induced by Doxorubicin.
Jiang X, Du Y, Meng X, Zhang H, Zhao D, Zhao L, Chen J, Xiao S, Jiang H
Dose-response : a publication of International Hormesis Society 2018 Oct-Dec;16(4):1559325818813061
Dose-response : a publication of International Hormesis Society 2018 Oct-Dec;16(4):1559325818813061
Long non-coding RNA OGFRP1 regulates LYPD3 expression by sponging miR-124-3p and promotes non-small cell lung cancer progression.
Tang LX, Chen GH, Li H, He P, Zhang Y, Xu XW
Biochemical and biophysical research communications 2018 Oct 28;505(2):578-585
Biochemical and biophysical research communications 2018 Oct 28;505(2):578-585
High expression of WNT7A predicts poor prognosis and promote tumor metastasis in pancreatic ductal adenocarcinoma.
Wu DJ, Jiang YS, He RZ, Tao LY, Yang MW, Fu XL, Yang JY, Zhu K
Scientific reports 2018 Oct 25;8(1):15792
Scientific reports 2018 Oct 25;8(1):15792
DNA-methylation-mediated silencing of miR-486-5p promotes colorectal cancer proliferation and migration through activation of PLAGL2/IGF2/β-catenin signal pathways.
Liu X, Chen X, Zeng K, Xu M, He B, Pan Y, Sun H, Pan B, Xu X, Xu T, Hu X, Wang S
Cell death & disease 2018 Oct 10;9(10):1037
Cell death & disease 2018 Oct 10;9(10):1037
Identification and characterization of a highly metastatic epithelial cancer cell line from rat tongue cancer.
Qin X, Yan M, Li R, Ye D, Zhang J, Xu Q, Feng Y, Sun Q, Jiang C, Chen W
Archives of oral biology 2018 Nov;95:58-67
Archives of oral biology 2018 Nov;95:58-67
RNA interference of long noncoding RNA HOTAIR suppresses autophagy and promotes apoptosis and sensitivity to cisplatin in oral squamous cell carcinoma.
Wang X, Liu W, Wang P, Li S
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2018 Nov;47(10):930-937
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2018 Nov;47(10):930-937
Isoliquiritigenin inhibits cell proliferation and migration through the PI3K/AKT signaling pathway in A549 lung cancer cells.
Tian T, Sun J, Wang J, Liu Y, Liu H
Oncology letters 2018 Nov;16(5):6133-6139
Oncology letters 2018 Nov;16(5):6133-6139
Toll-like receptor 4 shRNA attenuates lipopolysaccharide-induced epithelial-mesenchymal transition of intrahepatic biliary epithelial cells in rats.
Tang S, Jiang X, Wu L, Chen S, Chen L, Jiang J, Yan P, Wang F, Tu K, Wang D, Gu J, Zhao L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Nov;107:1210-1217
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Nov;107:1210-1217
Combination Therapy with DETA/NO and Clopidogrel Inhibits Metastasis in Murine Mammary Gland Cancer Models via Improved Vasoprotection.
Porshneva K, Papiernik D, Psurski M, Nowak M, Matkowski R, Ekiert M, Milczarek M, Banach J, Jarosz J, Wietrzyk J
Molecular pharmaceutics 2018 Nov 5;15(11):5277-5290
Molecular pharmaceutics 2018 Nov 5;15(11):5277-5290
Abnormally elevated USP37 expression in breast cancer stem cells regulates stemness, epithelial-mesenchymal transition and cisplatin sensitivity.
Qin T, Li B, Feng X, Fan S, Liu L, Liu D, Mao J, Lu Y, Yang J, Yu X, Zhang Q, Zhang J, Song B, Li M, Li L
Journal of experimental & clinical cancer research : CR 2018 Nov 27;37(1):287
Journal of experimental & clinical cancer research : CR 2018 Nov 27;37(1):287
RAB37 interacts directly with ATG5 and promotes autophagosome formation via regulating ATG5-12-16 complex assembly.
Sheng Y, Song Y, Li Z, Wang Y, Lin H, Cheng H, Zhou R
Cell death and differentiation 2018 May;25(5):918-934
Cell death and differentiation 2018 May;25(5):918-934
The PLGF/c-MYC/miR-19a axis promotes metastasis and stemness in gallbladder cancer.
Li H, Jin Y, Hu Y, Jiang L, Liu F, Zhang Y, Hao Y, Chen S, Wu X, Liu Y
Cancer science 2018 May;109(5):1532-1544
Cancer science 2018 May;109(5):1532-1544
CD74-ROS1 G2032R mutation transcriptionally up-regulates Twist1 in non-small cell lung cancer cells leading to increased migration, invasion, and resistance to crizotinib.
Gou W, Zhou X, Liu Z, Wang L, Shen J, Xu X, Li Z, Zhai X, Zuo D, Wu Y
Cancer letters 2018 May 28;422:19-28
Cancer letters 2018 May 28;422:19-28
A germline-specific role for the mTORC2 component Rictor in maintaining spermatogonial differentiation and intercellular adhesion in mouse testis.
Bai S, Cheng L, Zhang Y, Zhu C, Zhu Z, Zhu R, Cheng CY, Ye L, Zheng K
Molecular human reproduction 2018 May 1;24(5):244-259
Molecular human reproduction 2018 May 1;24(5):244-259
Dysregulated Expression of RPS4Y1 (Ribosomal Protein S4, Y-Linked 1) Impairs STAT3 (Signal Transducer and Activator of Transcription 3) Signaling to Suppress Trophoblast Cell Migration and Invasion in Preeclampsia.
Chen X, Tong C, Li H, Peng W, Li R, Luo X, Ge H, Ran Y, Li Q, Liu Y, Xiong X, Bai Y, Zhang H, Baker PN, Liu X, Qi H
Hypertension (Dallas, Tex. : 1979) 2018 Mar;71(3):481-490
Hypertension (Dallas, Tex. : 1979) 2018 Mar;71(3):481-490
Knockout of NCOA5 impairs proliferation and migration of hepatocellular carcinoma cells by suppressing epithelial-to-mesenchymal transition.
He J, Zhang W, Li A, Chen F, Luo R
Biochemical and biophysical research communications 2018 Jun 2;500(2):177-183
Biochemical and biophysical research communications 2018 Jun 2;500(2):177-183
RHBDF1 regulates APC-mediated stimulation of the epithelial-to-mesenchymal transition and proliferation of colorectal cancer cells in part via the Wnt/β-catenin signalling pathway.
Yuan H, Wei R, Xiao Y, Song Y, Wang J, Yu H, Fang T, Xu W, Mao S
Experimental cell research 2018 Jul 1;368(1):24-36
Experimental cell research 2018 Jul 1;368(1):24-36
Unfavorable effect of calcitriol and its low-calcemic analogs on metastasis of 4T1 mouse mammary gland cancer.
Anisiewicz A, Pawlik A, Filip-Psurska B, Turlej E, Dzimira S, Milczarek M, Gdesz K, Papiernik D, Jarosz J, Kłopotowska D, Kutner A, Mazur A, Wietrzyk J
International journal of oncology 2018 Jan;52(1):103-126
International journal of oncology 2018 Jan;52(1):103-126
PLCD3, a flotillin2-interacting protein, is involved in proliferation, migration and invasion of nasopharyngeal carcinoma cells.
Liu W, Liu X, Wang L, Zhu B, Zhang C, Jia W, Zhu H, Liu X, Zhong M, Xie D, Liu Y, Li S, Shi J, Lin J, Xia X, Jiang X, Ren C
Oncology reports 2018 Jan;39(1):45-52
Oncology reports 2018 Jan;39(1):45-52
PLZF inhibits proliferation and metastasis of gallbladder cancer by regulating IFIT2.
Shen H, Zhan M, Zhang Y, Huang S, Xu S, Huang X, He M, Yao Y, Man M, Wang J
Cell death & disease 2018 Jan 22;9(2):71
Cell death & disease 2018 Jan 22;9(2):71
Increased Expression of Cullin 3 in Nasopharyngeal Carcinoma and Knockdown Inhibits Proliferation and Invasion.
Zeng R, Tan G, Li W, Ma Y
Oncology research 2018 Jan 19;26(1):111-122
Oncology research 2018 Jan 19;26(1):111-122
MicroRNA-1271 functions as a metastasis and epithelial-mesenchymal transition inhibitor in human HCC by targeting the PTP4A1/c-Src axis.
Li C, Jiang Y, Miao R, Qu K, Zhang J, Liu C
International journal of oncology 2018 Feb;52(2):536-546
International journal of oncology 2018 Feb;52(2):536-546
PIM1 mediates epithelial-mesenchymal transition by targeting Smads and c-Myc in the nucleus and potentiates clear-cell renal-cell carcinoma oncogenesis.
Zhao B, Liu L, Mao J, Zhang Z, Wang Q, Li Q
Cell death & disease 2018 Feb 22;9(3):307
Cell death & disease 2018 Feb 22;9(3):307
Endogenous and exogenous galectin-3 promote the adhesion of tumor cells with low expression of MUC1 to HUVECs through upregulation of N-cadherin and CD44.
Cao Z, Hao Z, Xin M, Yu L, Wang L, Zhang Y, Zhang X, Guo X
Laboratory investigation; a journal of technical methods and pathology 2018 Dec;98(12):1642-1656
Laboratory investigation; a journal of technical methods and pathology 2018 Dec;98(12):1642-1656
Sodium Selenite inhibits mitophagy, downregulation and mislocalization of blood-testis barrier proteins of bovine Sertoli cell exposed to microcystin-leucine arginine (MC-LR) via TLR4/NF-kB and mitochondrial signaling pathways blockage.
Adegoke EO, Xue W, Machebe NS, Adeniran SO, Hao W, Chen W, Han Z, Guixue Z, Peng Z
Ecotoxicology and environmental safety 2018 Dec 30;166:165-175
Ecotoxicology and environmental safety 2018 Dec 30;166:165-175
Salinomycin suppresses cancer cell stemness and attenuates TGF-β-induced epithelial-mesenchymal transition of renal cell carcinoma cells.
Liu L, Wang Q, Mao J, Qin T, Sun Y, Yang J, Han Y, Li L, Li Q
Chemico-biological interactions 2018 Dec 25;296:145-153
Chemico-biological interactions 2018 Dec 25;296:145-153
Mitochondrial cytochrome P450 (CYP) 1B1 is responsible for melatonin-induced apoptosis in neural cancer cells.
Yu Z, Tian X, Peng Y, Sun Z, Wang C, Tang N, Li B, Jian Y, Wang W, Huo X, Ma X
Journal of pineal research 2018 Aug;65(1):e12478
Journal of pineal research 2018 Aug;65(1):e12478
LncRNA BDNF-AS inhibits proliferation, migration, invasion and EMT in oesophageal cancer cells by targeting miR-214.
Zhao H, Diao C, Wang X, Xie Y, Liu Y, Gao X, Han J, Li S
Journal of cellular and molecular medicine 2018 Aug;22(8):3729-3739
Journal of cellular and molecular medicine 2018 Aug;22(8):3729-3739
Phosphoglycerate Mutase 1 (PGAM1) Promotes Pancreatic Ductal Adenocarcinoma (PDAC) Metastasis by Acting as a Novel Downstream Target of the PI3K/Akt/mTOR Pathway.
Liu X, Tan X, Liu P, Wu Y, Qian S, Zhang X
Oncology research 2018 Aug 23;26(7):1123-1131
Oncology research 2018 Aug 23;26(7):1123-1131
Hypoxic Tumor-Derived Exosomal miR-301a Mediates M2 Macrophage Polarization via PTEN/PI3Kγ to Promote Pancreatic Cancer Metastasis.
Wang X, Luo G, Zhang K, Cao J, Huang C, Jiang T, Liu B, Su L, Qiu Z
Cancer research 2018 Aug 15;78(16):4586-4598
Cancer research 2018 Aug 15;78(16):4586-4598
Fentanyl Promotes Breast Cancer Cell Stemness and Epithelial-Mesenchymal Transition by Upregulating α1, 6-Fucosylation via Wnt/β-Catenin Signaling Pathway.
Yang HF, Yu M, Jin HD, Yao JQ, Lu ZL, Yabasin IB, Yan Q, Wen QP
Frontiers in physiology 2017;8:510
Frontiers in physiology 2017;8:510
β-Catenin Cooperates with CREB Binding Protein to Promote the Growth of Tumor Cells.
Yu W, Li L, Zheng F, Yang W, Zhao S, Tian C, Yin W, Chen Y, Guo W, Zou L, Deng W
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;44(2):467-478
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;44(2):467-478
Clopidogrel in a combined therapy with anticancer drugs-effect on tumor growth, metastasis, and treatment toxicity: Studies in animal models.
Denslow A, Świtalska M, Jarosz J, Papiernik D, Porshneva K, Nowak M, Wietrzyk J
PloS one 2017;12(12):e0188740
PloS one 2017;12(12):e0188740
Potential Involvement of Snail Members in Neuronal Survival and Astrocytic Migration during the Gecko Spinal Cord Regeneration.
Shen T, Wang Y, Zhang Q, Bai X, Wei S, Zhang X, Wang W, Yuan Y, Liu Y, Liu M, Gu X, Wang Y
Frontiers in cellular neuroscience 2017;11:113
Frontiers in cellular neuroscience 2017;11:113
MiR-211 inhibits cell epithelial-mesenchymal transition by targeting MMP9 in gastric cancer.
Wang XD, Wen FX, Liu BC, Song Y
International journal of clinical and experimental pathology 2017;10(7):7551-7558
International journal of clinical and experimental pathology 2017;10(7):7551-7558
Curcumin potentiates the potent antitumor activity of ACNU against glioblastoma by suppressing the PI3K/AKT and NF-κB/COX-2 signaling pathways.
Zhao J, Zhu J, Lv X, Xing J, Liu S, Chen C, Xu Y
OncoTargets and therapy 2017;10:5471-5482
OncoTargets and therapy 2017;10:5471-5482
Overexpression of RCC2 Enhances Cell Motility and Promotes Tumor Metastasis in Lung Adenocarcinoma by Inducing Epithelial-Mesenchymal Transition.
Pang B, Wu N, Guan R, Pang L, Li X, Li S, Tang L, Guo Y, Chen J, Sun D, Sun H, Dai J, Bai J, Ji G, Liu P, Liu A, Wang Q, Xiao S, Fu S, Jin Y
Clinical cancer research : an official journal of the American Association for Cancer Research 2017 Sep 15;23(18):5598-5610
Clinical cancer research : an official journal of the American Association for Cancer Research 2017 Sep 15;23(18):5598-5610
Honokiol inhibits bladder cancer cell invasion through repressing SRC-3 expression and epithelial-mesenchymal transition.
Shen L, Zhang F, Huang R, Yan J, Shen B
Oncology letters 2017 Oct;14(4):4294-4300
Oncology letters 2017 Oct;14(4):4294-4300
MicroRNA-23a promotes pancreatic cancer metastasis by targeting epithelial splicing regulator protein 1.
Wu G, Li Z, Jiang P, Zhang X, Xu Y, Chen K, Li X
Oncotarget 2017 Oct 10;8(47):82854-82871
Oncotarget 2017 Oct 10;8(47):82854-82871
ANGPTL1 Interacts with Integrin α1β1 to Suppress HCC Angiogenesis and Metastasis by Inhibiting JAK2/STAT3 Signaling.
Yan Q, Jiang L, Liu M, Yu D, Zhang Y, Li Y, Fang S, Li Y, Zhu YH, Yuan YF, Guan XY
Cancer research 2017 Nov 1;77(21):5831-5845
Cancer research 2017 Nov 1;77(21):5831-5845
Transducin (β)-like 1 X-linked receptor 1 promotes gastric cancer progression via the ERK1/2 pathway.
Zhou Q, Wang X, Yu Z, Wu X, Chen X, Li J, Zhu Z, Liu B, Su L
Oncogene 2017 Mar 30;36(13):1873-1886
Oncogene 2017 Mar 30;36(13):1873-1886
NUBPL, a novel metastasis-related gene, promotes colorectal carcinoma cell motility by inducing epithelial-mesenchymal transition.
Wang Y, Wu N, Sun D, Sun H, Tong D, Liu D, Pang B, Li S, Wei J, Dai J, Liu Y, Bai J, Geng J, Fu S, Jin Y
Cancer science 2017 Jun;108(6):1169-1176
Cancer science 2017 Jun;108(6):1169-1176
NTN4 is associated with breast cancer metastasis via regulation of EMT-related biomarkers.
Xu X, Yan Q, Wang Y, Dong X
Oncology reports 2017 Jan;37(1):449-457
Oncology reports 2017 Jan;37(1):449-457
Disruption of the c-Myc/miR-200b-3p/PRDX2 regulatory loop enhances tumor metastasis and chemotherapeutic resistance in colorectal cancer.
Lv Z, Wei J, You W, Wang R, Shang J, Xiong Y, Yang H, Yang X, Fu Z
Journal of translational medicine 2017 Dec 19;15(1):257
Journal of translational medicine 2017 Dec 19;15(1):257
SLC39A4 expression is associated with enhanced cell migration, cisplatin resistance, and poor survival in non-small cell lung cancer.
Wu DM, Liu T, Deng SH, Han R, Xu Y
Scientific reports 2017 Aug 3;7(1):7211
Scientific reports 2017 Aug 3;7(1):7211
Metformin reverses prostate cancer resistance to enzalutamide by targeting TGF-β1/STAT3 axis-regulated EMT.
Liu Q, Tong D, Liu G, Xu J, Do K, Geary K, Zhang D, Zhang J, Zhang Y, Li Y, Bi G, Lan W, Jiang J
Cell death & disease 2017 Aug 24;8(8):e3007
Cell death & disease 2017 Aug 24;8(8):e3007
Oral kanglaite injection (KLTI) attenuates the lung cancer-promoting effect of high-fat diet (HFD)-induced obesity.
Cao N, Ma X, Guo Z, Zheng Y, Geng S, Meng M, Du Z, Lin H, Duan Y, Du G
Oncotarget 2016 Sep 20;7(38):61093-61106
Oncotarget 2016 Sep 20;7(38):61093-61106
Effects of RECQ1 helicase silencing on non-small cell lung cancer cells.
Li L, Gao M, Song B, Zhang H, Wang Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 Oct;83:1227-1232
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 Oct;83:1227-1232
1-methylnicotinamide and its structural analog 1,4-dimethylpyridine for the prevention of cancer metastasis.
Blazejczyk A, Switalska M, Chlopicki S, Marcinek A, Gebicki J, Nowak M, Nasulewicz-Goldeman A, Wietrzyk J
Journal of experimental & clinical cancer research : CR 2016 Jul 13;35(1):110
Journal of experimental & clinical cancer research : CR 2016 Jul 13;35(1):110
FOXQ1 mediates the crosstalk between TGF-β and Wnt signaling pathways in the progression of colorectal cancer.
Peng X, Luo Z, Kang Q, Deng D, Wang Q, Peng H, Wang S, Wei Z
Cancer biology & therapy 2015;16(7):1099-109
Cancer biology & therapy 2015;16(7):1099-109
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 22018-1-AP(N-cadherin antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-N-cadherin (IP:22018-1-AP, 3ug; Detection:22018-1-AP 1:1500) with mouse brain tissue lysate 7000ug.
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The N-cadherin antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human N-cadherin. This antibody recognizes human, mouse, rat antigen. The N-cadherin antibody has been validated for the following applications: ELISA, IP, WB, IHC, FC analysis.
