Explore
Validate
Learn33-3900
antibody from Invitrogen Antibodies
Targeting: CDH2
CD325, CDHN, NCAD
Western blot Immunocytochemistry
Immunoprecipitation
Immunohistochemistry Flow cytometry Other assayAntibody data
- Antibody Data
- Antigen structure
- References [221]
- Comments [0]
- Validations
- Western blot [2]
- Immunocytochemistry [2]
- Flow cytometry [1]
- Other assay [15]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 33-3900 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- N-cadherin Monoclonal Antibody (3B9)
- Antibody type
- Monoclonal
- Antigen
- Recombinant full-length protein
- Description
- This antibody is specific for N-cadherin and does not cross-react with other cadherin family members including P- and E-cadherins. For IHC with this antibody use formalin-fixed, paraffin-embedded tissue and heat-induced epitope retrieval.
- Reactivity
- Human, Mouse, Rat, Chicken/Avian, Porcine
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 3B9
- Vial size
- 100 µg
- Concentration
- 0.5 mg/mL
- Storage
- -20°C
Submitted references Antagonizing STK25 Signaling Suppresses the Development of Hepatocellular Carcinoma Through Targeting Metabolic, Inflammatory, and Pro-Oncogenic Pathways.
Impact of phospholipase C β1 in glioblastoma: a study on the main mechanisms of tumor aggressiveness.
Acquired hydrocephalus is associated with neuroinflammation, progenitor loss, and cellular changes in the subventricular zone and periventricular white matter.
Mfsd2b and Spns2 are essential for maintenance of blood vessels during development and in anaphylactic shock.
Pluripotent stem cell-derived corneal endothelial cells as an alternative to donor corneal endothelium in keratoplasty.
Drebrin, an actin-binding protein, is required for lens morphogenesis and growth.
Deficiency of C-X-C chemokine receptor type 5 (CXCR5) gene causes dysfunction of retinal pigment epithelium cells.
The novel ZEB1-upregulated protein PRTG induced by Helicobacter pylori infection promotes gastric carcinogenesis through the cGMP/PKG signaling pathway.
Pluripotency state regulates cytoneme selectivity and self-organization of embryonic stem cells.
FGF18-FGFR2 signaling triggers the activation of c-Jun-YAP1 axis to promote carcinogenesis in a subgroup of gastric cancer patients and indicates translational potential.
R-spondin2 signaling is required for oocyte-driven intercellular communication and follicular growth.
Extracellular vesicles from mast cells induce mesenchymal transition in airway epithelial cells.
TGF-β1 relieves epithelial-mesenchymal transition reduction in hypospadias induced by DEHP in rats.
LncRNA ANCR promotes hepatocellular carcinoma metastasis through upregulating HNRNPA1 expression.
Connexin-43 reduction prevents muscle defects in a mouse model of manifesting Duchenne muscular dystrophy female carriers.
ZO-1 Regulates Intercalated Disc Composition and Atrioventricular Node Conduction.
Differential expression of cell-cell junction proteins in the testis, epididymis, and ductus deferens of domestic turkeys (Meleagris gallopavo) with white and yellow semen.
Disabled Homolog 2 (DAB2) Protein in Tumor Microenvironment Correlates with Aggressive Phenotype in Human Urothelial Carcinoma of the Bladder.
Inhibition of Sema4D/PlexinB1 signaling alleviates vascular dysfunction in diabetic retinopathy.
Promoting roles of long non-coding RNA FAM83H-AS1 in bladder cancer growth, metastasis, and angiogenesis through the c-Myc-mediated ULK3 upregulation.
Metavinculin modulates force transduction in cell adhesion sites.
FDPS promotes glioma growth and macrophage recruitment by regulating CCL20 via Wnt/β-catenin signalling pathway.
Transcriptional downregulation of MHC class I and melanoma de- differentiation in resistance to PD-1 inhibition.
Metabolic switch and epithelial-mesenchymal transition cooperate to regulate pluripotency.
Prevention of connexin-43 remodeling protects against Duchenne muscular dystrophy cardiomyopathy.
Secreted protein acidic and rich in cysteine (SPARC) induces epithelial-mesenchymal transition, enhancing migration and invasion, and is associated with high Gleason score in prostate cancer.
Visco-Node-Pore Sensing: A Microfluidic Rheology Platform to Characterize Viscoelastic Properties of Epithelial Cells.
Elevated endothelial Sox2 causes lumen disruption and cerebral arteriovenous malformations.
Defining new mechanistic roles for αII spectrin in cardiac function.
New Insights into the Role of Polybromo-1 in Prostate Cancer.
Ankyrin-B dysfunction predisposes to arrhythmogenic cardiomyopathy and is amenable to therapy.
mTORC1/rpS6 signaling complex modifies BTB transport function: an in vivo study using the adjudin model.
FGF18, a prominent player in FGF signaling, promotes gastric tumorigenesis through autocrine manner and is negatively regulated by miR-590-5p.
Planar cell polarity protein Dishevelled 3 (Dvl3) regulates ectoplasmic specialization (ES) dynamics in the testis through changes in cytoskeletal organization.
The N-cadherin interactome in primary cardiomyocytes as defined using quantitative proximity proteomics.
Ankyrin-G regulated epithelial phenotype is required for mouse lens morphogenesis and growth.
Pannexin1 Is Associated with Enhanced Epithelial-To-Mesenchymal Transition in Human Patient Breast Cancer Tissues and in Breast Cancer Cell Lines.
YBX-1 mediated sorting of miR-133 into hypoxia/reoxygenation-induced EPC-derived exosomes to increase fibroblast angiogenesis and MEndoT.
Modeling the effect of ascites-induced compression on ovarian cancer multicellular aggregates.
Differential Wnt-mediated programming and arrhythmogenesis in right versus left ventricles.
Dynein 1 supports spermatid transport and spermiation during spermatogenesis in the rat testis.
SRGAP1, a crucial target of miR-340 and miR-124, functions as a potential oncogene in gastric tumorigenesis.
Matrine inhibits prostate cancer via activation of the unfolded protein response/endoplasmic reticulum stress signaling and reversal of epithelial to mesenchymal transition.
Nitric oxide-sensitive guanylyl cyclase stimulation improves experimental heart failure with preserved ejection fraction.
Actin nucleator Spire 1 is a regulator of ectoplasmic specialization in the testis.
Intercalated cushion cells within the cardiac outflow tract are derived from the myocardial troponin T type 2 (Tnnt2) Cre lineage.
Direct Cardiac Reprogramming as a Novel Therapeutic Strategy for Treatment of Myocardial Infarction.
Cellular inhibitor of apoptosis protein 2 promotes the epithelial-mesenchymal transition in triple-negative breast cancer cells through activation of the AKT signaling pathway.
Electronic Cigarette Smoke Impairs Normal Mesenchymal Stem Cell Differentiation.
TGF-β1 affects cell-cell adhesion in the heart in an NCAM1-dependent mechanism.
Mosaic Analysis with Double Markers Reveals Distinct Sequential Functions of Lgl1 in Neural Stem Cells.
Mild hypothermia preserves myocardial conduction during ischemia by maintaining gap junction intracellular communication and Na(+) channel function.
Identification of a Novel Human E-Cadherin Splice Variant and Assessment of Its Effects Upon EMT-Related Events.
A Critical Role of Presynaptic Cadherin/Catenin/p140Cap Complexes in Stabilizing Spines and Functional Synapses in the Neocortex.
Neurons secrete miR-132-containing exosomes to regulate brain vascular integrity.
Heterogeneous Cadherin Expression and Multicellular Aggregate Dynamics in Ovarian Cancer Dissemination.
Defective CFTR leads to aberrant β-catenin activation and kidney fibrosis.
Intermittent hypoxia causes NOX2-dependent remodeling of atrial connexins.
Proteomic analysis of ovarian cancer cells during epithelial-mesenchymal transition (EMT) induced by epidermal growth factor (EGF) reveals mechanisms of cell cycle control.
Decreased WNT/β-catenin signalling contributes to the pathogenesis of dilated cardiomyopathy caused by mutations in the lamin a/C gene.
Amplification of R-spondin1 signaling induces granulosa cell fate defects and cancers in mouse adult ovary.
Regulation of the blood-testis barrier by a local axis in the testis: role of laminin α2 in the basement membrane.
MicroRNA-661 modulates redox and metabolic homeostasis in colon cancer.
Inhibition of soluble epoxide hydrolase prevents diabetic retinopathy.
Roles of TGFβ and FGF signals during growth and differentiation of mouse lens epithelial cell in vitro.
Spontaneous acquisition of infinite proliferative capacity by a rabbit corneal endothelial cell line with maintenance of phenotypic and physiological characteristics.
Perfluorooctanesulfonate (PFOS)-induced Sertoli cell injury through a disruption of F-actin and microtubule organization is mediated by Akt1/2.
The Apical Localization of Na(+), K(+)-ATPase in Cultured Human Retinal Pigment Epithelial Cells Depends on Expression of the β(2) Subunit.
Isolation of an ES-Derived Cardiovascular Multipotent Cell Population Based on VE-Cadherin Promoter Activity.
Biased Expression of the FOXP3Δ3 Isoform in Aggressive Bladder Cancer Mediates Differentiation and Cisplatin Chemotherapy Resistance.
Interleukin 1alpha-induced disruption of the Sertoli cell cytoskeleton affects gap junctional communication.
Planar Cell Polarity (PCP) Protein Vangl2 Regulates Ectoplasmic Specialization Dynamics via Its Effects on Actin Microfilaments in the Testes of Male Rats.
An epithelial to mesenchymal transition programme does not usually drive the phenotype of invasive lobular carcinomas.
Specific deletion of AMP-activated protein kinase (α1AMPK) in mouse Sertoli cells modifies germ cell quality.
Polarity protein Crumbs homolog-3 (CRB3) regulates ectoplasmic specialization dynamics through its action on F-actin organization in Sertoli cells.
Rescue of perfluorooctanesulfonate (PFOS)-mediated Sertoli cell injury by overexpression of gap junction protein connexin 43.
Phosphorylation at Connexin43 Serine-368 Is Necessary for Myocardial Conduction During Metabolic Stress.
The CaSm (LSm1) oncogene promotes transformation, chemoresistance and metastasis of pancreatic cancer cells.
Cell coupling mediated by connexin 26 selectively contributes to reduced adhesivity and increased migration.
Overexpression of plastin 3 in Sertoli cells disrupts actin microfilament bundle homeostasis and perturbs the tight junction barrier.
Connexin 43 reboots meiosis and reseals blood-testis barrier following toxicant-mediated aspermatogenesis and barrier disruption.
Two-Pore K+ Channel TREK-1 Regulates Sinoatrial Node Membrane Excitability.
Fibroblast growth factor receptor 2 (FGFR2) is required for corneal epithelial cell proliferation and differentiation during embryonic development.
Actin-bundling protein plastin 3 is a regulator of ectoplasmic specialization dynamics during spermatogenesis in the rat testis.
Characterization of the equine blood-testis barrier during tubular development in normal and cryptorchid stallions.
Serine Protease Activation Essential for Endothelial-Mesenchymal Transition in Vascular Calcification.
Cardiomyocyte-specific overexpression of the ubiquitin ligase Wwp1 contributes to reduction in Connexin 43 and arrhythmogenesis.
Defective autophagy is a key feature of cerebral cavernous malformations.
ESRP2 controls an adult splicing programme in hepatocytes to support postnatal liver maturation.
Heterogeneity between triple negative breast cancer cells due to differential activation of Wnt and PI3K/AKT pathways.
Flutamide alters the distribution of c-Src and affects the N-cadherin-β-catenin complex in the seminiferous epithelium of adult rat.
miR-200c/Bmi1 axis and epithelial-mesenchymal transition contribute to acquired resistance to BRAF inhibitor treatment.
Loss of ATM accelerates pancreatic cancer formation and epithelial-mesenchymal transition.
Expression of miR-200c in claudin-low breast cancer alters stem cell functionality, enhances chemosensitivity and reduces metastatic potential.
Platelets enhance tissue factor protein and metastasis initiating cell markers, and act as chemoattractants increasing the migration of ovarian cancer cells.
Cdk5-mediated phosphorylation of RapGEF2 controls neuronal migration in the developing cerebral cortex.
Dlg5 regulates dendritic spine formation and synaptogenesis by controlling subcellular N-cadherin localization.
HNF4α induced chemosensitivity to oxaliplatin and 5-FU mediated by OCT1 and CNT3 in renal cell carcinoma.
Connexin40 abnormalities and atrial fibrillation in the human heart.
rpS6 regulates blood-testis barrier dynamics through Akt-mediated effects on MMP-9.
TRPV2 is critical for the maintenance of cardiac structure and function in mice.
14-3-3γ-Mediated transport of plakoglobin to the cell border is required for the initiation of desmosome assembly in vitro and in vivo.
LIM-homeobox gene 2 promotes tumor growth and metastasis by inducing autocrine and paracrine PDGF-B signaling.
VEGF-mediated angiogenesis links EMT-induced cancer stemness to tumor initiation.
Environmental toxicants perturb human Sertoli cell adhesive function via changes in F-actin organization mediated by actin regulatory proteins.
Calpain-dependent cleavage of N-cadherin is involved in the progression of post-myocardial infarction remodeling.
Perfluorooctanesulfonate (PFOS) perturbs male rat Sertoli cell blood-testis barrier function by affecting F-actin organization via p-FAK-Tyr(407): an in vitro study.
Novel three-dimensional in vitro models of ovarian endometriosis.
Isolation and characterization of a primary proximal tubular epithelial cell model from human kidney by CD10/CD13 double labeling.
Rai14 (retinoic acid induced protein 14) is involved in regulating f-actin dynamics at the ectoplasmic specialization in the rat testis*.
Toward a molecular pathologic classification of urothelial carcinoma.
Three-dimensional cell culturing by magnetic levitation.
A three-dimensional microenvironment alters protein expression and chemosensitivity of epithelial ovarian cancer cells in vitro.
Palladin is a regulator of actin filament bundles at the ectoplasmic specialization in adult rat testes.
The Meckel syndrome protein meckelin (TMEM67) is a key regulator of cilia function but is not required for tissue planar polarity.
The Xin repeat-containing protein, mXinβ, initiates the maturation of the intercalated discs during postnatal heart development.
The p63 protein isoform ΔNp63α inhibits epithelial-mesenchymal transition in human bladder cancer cells: role of MIR-205.
Generation of a human airway epithelium derived basal cell line with multipotent differentiation capacity.
Further evidence that E-cadherin is not a tumour suppressor gene in invasive ductal carcinoma of the breast: an immunohistochemical study.
Cardiovascular dysregulation of miR-17-92 causes a lethal hypertrophic cardiomyopathy and arrhythmogenesis.
N-cadherin in neuroblastoma disease: expression and clinical significance.
Analysis of a Jup hypomorphic allele reveals a critical threshold for postnatal viability.
Loss of cadherin-binding proteins β-catenin and plakoglobin in the heart leads to gap junction remodeling and arrhythmogenesis.
Cadherin-11 contributes to pulmonary fibrosis: potential role in TGF-β production and epithelial to mesenchymal transition.
Immunohistochemical study of the epithelial-mesenchymal transition phenotype in cancer of unknown primary: incidence, correlations and prognostic utility.
Regulation of retinal progenitor expansion by Frizzled receptors: implications for microphthalmia and retinal coloboma.
Microtubule affinity-regulating kinase 4 (MARK4) is a component of the ectoplasmic specialization in the rat testis.
Alterations of epithelial stem cell marker patterns in human diabetic corneas and effects of c-met gene therapy.
A novel gelatin hydrogel carrier sheet for corneal endothelial transplantation.
Adipose tissue-derived stem cell in vitro differentiation in a three-dimensional dental bud structure.
Cardiac tissue-restricted deletion of plakoglobin results in progressive cardiomyopathy and activation of {beta}-catenin signaling.
EH-myomesin splice isoform is a novel marker for dilated cardiomyopathy.
ZO-1 determines adherens and gap junction localization at intercalated disks.
E/N-cadherin switch mediates cancer progression via TGF-β-induced epithelial-to-mesenchymal transition in extrahepatic cholangiocarcinoma.
Rac1 GTPase-deficient mouse lens exhibits defects in shape, suture formation, fiber cell migration and survival.
Interleukin-1alpha is a regulator of the blood-testis barrier.
Deletion of p120-catenin results in a tumor microenvironment with inflammation and cancer that establishes it as a tumor suppressor gene.
Granzyme B is expressed in urothelial carcinoma and promotes cancer cell invasion.
Differential effects of testosterone and TGF-β3 on endocytic vesicle-mediated protein trafficking events at the blood-testis barrier.
Adjudin-mediated Sertoli-germ cell junction disassembly affects Sertoli cell barrier function in vitro and in vivo.
Insights from a desmoplakin mutation identified in lethal acantholytic epidermolysis bullosa.
Expression analysis of epithelial cadherin and related proteins in IBH-6 and IBH-4 human breast cancer cell lines.
Neural cadherin is expressed in human gametes and participates in sperm-oocyte interaction events.
Variable expression of tenascin-C, osteopontin and fibronectin in inflammatory myofibroblastic tumour of the lung.
Monoclonal antibody targeting of N-cadherin inhibits prostate cancer growth, metastasis and castration resistance.
The canonical NF-kappaB pathway governs mammary tumorigenesis in transgenic mice and tumor stem cell expansion.
Exploring the peritoneal surface malignancy phenotype--a pilot immunohistochemical study of human pseudomyxoma peritonei and derived animal models.
Epigenetic programming of mu-opioid receptor gene in mouse brain is regulated by MeCP2 and Brg1 chromatin remodelling factor.
N-cadherin in the maintenance of human corneal limbal epithelial progenitor cells in vitro.
The expression of Twist has an impact on survival in human bladder cancer and is influenced by the smoking status.
RAB13 participates in ectoplasmic specialization dynamics in the rat testis.
N-cadherin serves as diagnostic biomarker in intrahepatic and perihilar cholangiocarcinomas.
Slit2 inhibits glioma cell invasion in the brain by suppression of Cdc42 activity.
Expressing connexin 43 in breast cancer cells reduces their metastasis to lungs.
Phenotypic plasticity of neoplastic ovarian epithelium: unique cadherin profiles in tumor progression.
N-cadherin haploinsufficiency affects cardiac gap junctions and arrhythmic susceptibility.
Temporal and spatial localization of nectin-1 and l-afadin during synaptogenesis in hippocampal neurons.
Blood-testis barrier dynamics are regulated by testosterone and cytokines via their differential effects on the kinetics of protein endocytosis and recycling in Sertoli cells.
JNK signaling pathway is required for bFGF-mediated surface cadherin downregulation on HUVEC.
Coexpression of two mesenchymal cadherins, cadherin 11 and N-cadherin, on murine fibroblast-like synoviocytes.
Rab4A GTPase catenin interactions are involved in cell junction dynamics in the testis.
Paucity of pericytes in germinal matrix vasculature of premature infants.
IQ-domain GTPase-activating protein 1 regulates beta-catenin at membrane ruffles and its role in macropinocytosis of N-cadherin and adenomatous polyposis coli.
Evidence of endogenous mu opioid receptor regulation by epigenetic control of the promoters.
Bin1 ablation in mammary gland delays tissue remodeling and drives cancer progression.
Foxe3 is required for morphogenesis and differentiation of the anterior segment of the eye and is sensitive to Pax6 gene dosage.
Aconitine alters connexin43 phosphorylation status and [Ca2+] oscillation patterns in cultured ventricular myocytes of neonatal rats.
Coxsackie and adenovirus receptor (CAR) is a product of Sertoli and germ cells in rat testes which is localized at the Sertoli-Sertoli and Sertoli-germ cell interface.
Genetic profiling of epithelial cells expressing E-cadherin repressors reveals a distinct role for Snail, Slug, and E47 factors in epithelial-mesenchymal transition.
N-cadherin as a novel prognostic marker of progression in superficial urothelial tumors.
Laminin alpha 3 forms a complex with beta3 and gamma3 chains that serves as the ligand for alpha 6beta1-integrin at the apical ectoplasmic specialization in adult rat testes.
Adjudin-mediated junction restructuring in the seminiferous epithelium leads to displacement of soluble guanylate cyclase from adherens junctions.
Dynamin II interacts with the cadherin- and occludin-based protein complexes at the blood-testis barrier in adult rat testes.
Notch1 signaling promotes primary melanoma progression by activating mitogen-activated protein kinase/phosphatidylinositol 3-kinase-Akt pathways and up-regulating N-cadherin expression.
Molecular characterization of tumour heterogeneity and malignant mesothelioma cell differentiation by gene profiling.
The duality of beta-catenin function: a requirement in lens morphogenesis and signaling suppression of lens fate in periocular ectoderm.
Modulating the strength of cadherin adhesion: evidence for a novel adhesion complex.
Disruption of Sertoli-germ cell adhesion function in the seminiferous epithelium of the rat testis can be limited to adherens junctions without affecting the blood-testis barrier integrity: an in vivo study using an androgen suppression model.
Gene expression in thyroid autonomous adenomas provides insight into their physiopathology.
Connexin43 associated with an N-cadherin-containing multiprotein complex is required for gap junction formation in NIH3T3 cells.
Simultaneous bilateral breast carcinoma: Histopathological characteristics and CD44/catenin-cadherin profile.
Effect of N-cadherin misexpression by the mammary epithelium in mice.
P-cadherin overexpression is an indicator of clinical outcome in invasive breast carcinomas and is associated with CDH3 promoter hypomethylation.
Blood-testis barrier dynamics are regulated by {alpha}2-macroglobulin via the c-Jun N-terminal protein kinase pathway.
TGF-beta3 regulates anchoring junction dynamics in the seminiferous epithelium of the rat testis via the Ras/ERK signaling pathway: An in vivo study.
N-cadherin acts upstream of VE-cadherin in controlling vascular morphogenesis.
Breast cancer metastatic potential: correlation with increased heterotypic gap junctional intercellular communication between breast cancer cells and osteoblastic cells.
Sertoli-Sertoli and Sertoli-germ cell interactions and their significance in germ cell movement in the seminiferous epithelium during spermatogenesis.
Zyxin, axin, and Wiskott-Aldrich syndrome protein are adaptors that link the cadherin/catenin protein complex to the cytoskeleton at adherens junctions in the seminiferous epithelium of the rat testis.
Immunohistochemical patterns for alpha- and beta-catenin, E- and N-cadherin expression in ovarian epithelial tumors.
Interactions of proteases, protease inhibitors, and the beta1 integrin/laminin gamma3 protein complex in the regulation of ectoplasmic specialization dynamics in the rat testis.
Pilomatrix carcinoma with lymph node metastases.
Pilomatrix carcinoma with lymph node metastases.
Oncoprotein profiles of primary peritoneal malignant mixed müllerian tumors.
Oncoprotein profiles of primary peritoneal malignant mixed müllerian tumors.
Alpha5beta1 integrin mediates strong tissue cohesion.
Is the cadherin/catenin complex a functional unit of cell-cell actin-based adherens junctions in the rat testis?
Is the cadherin/catenin complex a functional unit of cell-cell actin-based adherens junctions in the rat testis?
Value of E-cadherin and N-cadherin immunostaining in the diagnosis of mesothelioma.
Value of E-cadherin and N-cadherin immunostaining in the diagnosis of mesothelioma.
Cadherin-mediated adhesion is essential for myofibril continuity across the plasma membrane but not for assembly of the contractile apparatus.
Cadherin-mediated adhesion is essential for myofibril continuity across the plasma membrane but not for assembly of the contractile apparatus.
Mucoepidermoid carcinoma of the thyroid: a tumour histotype characterised by P-cadherin neoexpression and marked abnormalities of E-cadherin/catenins complex.
P-cadherin expression is associated with high-grade ductal carcinoma in situ of the breast.
P-cadherin expression is associated with high-grade ductal carcinoma in situ of the breast.
Epithelial-type and neural-type cadherin expression in malignant noncarcinomatous neoplasms with epithelioid features that involve the soft tissues.
Remodeling the intercalated disc leads to cardiomyopathy in mice misexpressing cadherins in the heart.
Remodeling the intercalated disc leads to cardiomyopathy in mice misexpressing cadherins in the heart.
The Erbin PDZ domain binds with high affinity and specificity to the carboxyl termini of delta-catenin and ARVCF.
E-cadherin suppresses cellular transformation by inhibiting beta-catenin signaling in an adhesion-independent manner.
E-cadherin suppresses cellular transformation by inhibiting beta-catenin signaling in an adhesion-independent manner.
N-cadherin-mediated intercellular interactions promote survival and migration of melanoma cells.
Cadherin junctions in mammary tumors.
Cadherin junctions in mammary tumors.
Abnormalities of the E-cadherin/catenin adhesion complex in classical papillary thyroid carcinoma and in its diffuse sclerosing variant.
Modulation of mouse neural crest cell motility by N-cadherin and connexin 43 gap junctions.
Rescuing the N-cadherin knockout by cardiac-specific expression of N- or E-cadherin.
Rescuing the N-cadherin knockout by cardiac-specific expression of N- or E-cadherin.
Dosage requirement and allelic expression of PAX6 during lens placode formation.
The differential expression of N-cadherin and E-cadherin distinguishes pleural mesotheliomas from lung adenocarcinomas.
The differential expression of N-cadherin and E-cadherin distinguishes pleural mesotheliomas from lung adenocarcinomas.
Kurhe Y, Caputo M, Cansby E, Xia Y, Kumari S, Anand SK, Howell BW, Marschall HU, Mahlapuu M
Cellular and molecular gastroenterology and hepatology 2022;13(2):405-423
Cellular and molecular gastroenterology and hepatology 2022;13(2):405-423
Impact of phospholipase C β1 in glioblastoma: a study on the main mechanisms of tumor aggressiveness.
Ratti S, Marvi MV, Mongiorgi S, Obeng EO, Rusciano I, Ramazzotti G, Morandi L, Asioli S, Zoli M, Mazzatenta D, Suh PG, Manzoli L, Cocco L
Cellular and molecular life sciences : CMLS 2022 Mar 18;79(4):195
Cellular and molecular life sciences : CMLS 2022 Mar 18;79(4):195
Acquired hydrocephalus is associated with neuroinflammation, progenitor loss, and cellular changes in the subventricular zone and periventricular white matter.
Garcia-Bonilla M, Castaneyra-Ruiz L, Zwick S, Talcott M, Otun A, Isaacs AM, Morales DM, Limbrick DD Jr, McAllister JP 2nd
Fluids and barriers of the CNS 2022 Feb 22;19(1):17
Fluids and barriers of the CNS 2022 Feb 22;19(1):17
Mfsd2b and Spns2 are essential for maintenance of blood vessels during development and in anaphylactic shock.
Le TNU, Nguyen TQ, Kalailingam P, Nguyen YTK, Sukumar VK, Tan CKH, Tukijan F, Couty L, Hasan Z, Del Gaudio I, Wenk MR, Cazenave-Gassiot A, Camerer E, Nguyen LN
Cell reports 2022 Aug 16;40(7):111208
Cell reports 2022 Aug 16;40(7):111208
Pluripotent stem cell-derived corneal endothelial cells as an alternative to donor corneal endothelium in keratoplasty.
Ali M, Khan SY, Gottsch JD, Hutchinson EK, Khan A, Riazuddin SA
Stem cell reports 2021 Sep 14;16(9):2320-2335
Stem cell reports 2021 Sep 14;16(9):2320-2335
Drebrin, an actin-binding protein, is required for lens morphogenesis and growth.
Karnam S, Maddala R, Stiber JA, Rao PV
Developmental dynamics : an official publication of the American Association of Anatomists 2021 Nov;250(11):1600-1617
Developmental dynamics : an official publication of the American Association of Anatomists 2021 Nov;250(11):1600-1617
Deficiency of C-X-C chemokine receptor type 5 (CXCR5) gene causes dysfunction of retinal pigment epithelium cells.
Lennikov A, Mukwaya A, Saddala MS, Huang H
Laboratory investigation; a journal of technical methods and pathology 2021 Feb;101(2):228-244
Laboratory investigation; a journal of technical methods and pathology 2021 Feb;101(2):228-244
The novel ZEB1-upregulated protein PRTG induced by Helicobacter pylori infection promotes gastric carcinogenesis through the cGMP/PKG signaling pathway.
Xiang T, Yuan C, Guo X, Wang H, Cai Q, Xiang Y, Luo W, Liu G
Cell death & disease 2021 Feb 4;12(2):150
Cell death & disease 2021 Feb 4;12(2):150
Pluripotency state regulates cytoneme selectivity and self-organization of embryonic stem cells.
Junyent S, Reeves J, Gentleman E, Habib SJ
The Journal of cell biology 2021 Apr 5;220(4)
The Journal of cell biology 2021 Apr 5;220(4)
FGF18-FGFR2 signaling triggers the activation of c-Jun-YAP1 axis to promote carcinogenesis in a subgroup of gastric cancer patients and indicates translational potential.
Zhang J, Wong CC, Leung KT, Wu F, Zhou Y, Tong JHM, Chan RCK, Li H, Wang Y, Yan H, Liu L, Wu WKK, Chan MWY, Cheng ASL, Yu J, Wong N, Lo KW, To KF, Kang W
Oncogene 2020 Oct;39(43):6647-6663
Oncogene 2020 Oct;39(43):6647-6663
R-spondin2 signaling is required for oocyte-driven intercellular communication and follicular growth.
De Cian MC, Gregoire EP, Le Rolle M, Lachambre S, Mondin M, Bell S, Guigon CJ, Chassot AA, Chaboissier MC
Cell death and differentiation 2020 Oct;27(10):2856-2871
Cell death and differentiation 2020 Oct;27(10):2856-2871
Extracellular vesicles from mast cells induce mesenchymal transition in airway epithelial cells.
Yin Y, Shelke GV, Lässer C, Brismar H, Lötvall J
Respiratory research 2020 May 1;21(1):101
Respiratory research 2020 May 1;21(1):101
TGF-β1 relieves epithelial-mesenchymal transition reduction in hypospadias induced by DEHP in rats.
Zhou Y, Huang F, Liu Y, Li D, Zhou Y, Shen L, Long C, Liu X, Wei G
Pediatric research 2020 Mar;87(4):639-646
Pediatric research 2020 Mar;87(4):639-646
LncRNA ANCR promotes hepatocellular carcinoma metastasis through upregulating HNRNPA1 expression.
Wen Z, Lian L, Ding H, Hu Y, Xiao Z, Xiong K, Yang Q
RNA biology 2020 Mar;17(3):381-394
RNA biology 2020 Mar;17(3):381-394
Connexin-43 reduction prevents muscle defects in a mouse model of manifesting Duchenne muscular dystrophy female carriers.
Nouet J, Himelman E, Lahey KC, Zhao Q, Fraidenraich D
Scientific reports 2020 Mar 30;10(1):5683
Scientific reports 2020 Mar 30;10(1):5683
ZO-1 Regulates Intercalated Disc Composition and Atrioventricular Node Conduction.
Dai W, Nadadur RD, Brennan JA, Smith HL, Shen KM, Gadek M, Laforest B, Wang M, Gemel J, Li Y, Zhang J, Ziman BD, Yan J, Ai X, Beyer EC, Lakata EG, Kasthuri N, Efimov IR, Broman MT, Moskowitz IP, Shen L, Weber CR
Circulation research 2020 Jul 3;127(2):e28-e43
Circulation research 2020 Jul 3;127(2):e28-e43
Differential expression of cell-cell junction proteins in the testis, epididymis, and ductus deferens of domestic turkeys (Meleagris gallopavo) with white and yellow semen.
Pardyak L, Kaminska A, Brzoskwinia M, Hejmej A, Kotula-Balak M, Jankowski J, Ciereszko A, Bilinska B
Poultry science 2020 Jan;99(1):555-566
Poultry science 2020 Jan;99(1):555-566
Disabled Homolog 2 (DAB2) Protein in Tumor Microenvironment Correlates with Aggressive Phenotype in Human Urothelial Carcinoma of the Bladder.
Itami Y, Miyake M, Ohnishi S, Tatsumi Y, Gotoh D, Hori S, Morizawa Y, Iida K, Ohnishi K, Nakai Y, Inoue T, Anai S, Tanaka N, Fujii T, Shimada K, Furuya H, Khadka VS, Deng Y, Fujimoto K
Diagnostics (Basel, Switzerland) 2020 Jan 20;10(1)
Diagnostics (Basel, Switzerland) 2020 Jan 20;10(1)
Inhibition of Sema4D/PlexinB1 signaling alleviates vascular dysfunction in diabetic retinopathy.
Wu JH, Li YN, Chen AQ, Hong CD, Zhang CL, Wang HL, Zhou YF, Li PC, Wang Y, Mao L, Xia YP, He QW, Jin HJ, Yue ZY, Hu B
EMBO molecular medicine 2020 Feb 7;12(2):e10154
EMBO molecular medicine 2020 Feb 7;12(2):e10154
Promoting roles of long non-coding RNA FAM83H-AS1 in bladder cancer growth, metastasis, and angiogenesis through the c-Myc-mediated ULK3 upregulation.
Liu B, Gao W, Sun W, Li L, Wang C, Yang X, Liu J, Guo Y
Cell cycle (Georgetown, Tex.) 2020 Dec;19(24):3546-3562
Cell cycle (Georgetown, Tex.) 2020 Dec;19(24):3546-3562
Metavinculin modulates force transduction in cell adhesion sites.
Kanoldt V, Kluger C, Barz C, Schweizer AL, Ramanujam D, Windgasse L, Engelhardt S, Chrostek-Grashoff A, Grashoff C
Nature communications 2020 Dec 17;11(1):6403
Nature communications 2020 Dec 17;11(1):6403
FDPS promotes glioma growth and macrophage recruitment by regulating CCL20 via Wnt/β-catenin signalling pathway.
Chen Z, Chen G, Zhao H
Journal of cellular and molecular medicine 2020 Aug;24(16):9055-9066
Journal of cellular and molecular medicine 2020 Aug;24(16):9055-9066
Transcriptional downregulation of MHC class I and melanoma de- differentiation in resistance to PD-1 inhibition.
Lee JH, Shklovskaya E, Lim SY, Carlino MS, Menzies AM, Stewart A, Pedersen B, Irvine M, Alavi S, Yang JYH, Strbenac D, Saw RPM, Thompson JF, Wilmott JS, Scolyer RA, Long GV, Kefford RF, Rizos H
Nature communications 2020 Apr 20;11(1):1897
Nature communications 2020 Apr 20;11(1):1897
Metabolic switch and epithelial-mesenchymal transition cooperate to regulate pluripotency.
Sun H, Yang X, Liang L, Zhang M, Li Y, Chen J, Wang F, Yang T, Meng F, Lai X, Li C, He J, He M, Xu Q, Li Q, Lin L, Pei D, Zheng H
The EMBO journal 2020 Apr 15;39(8):e102961
The EMBO journal 2020 Apr 15;39(8):e102961
Prevention of connexin-43 remodeling protects against Duchenne muscular dystrophy cardiomyopathy.
Himelman E, Lillo MA, Nouet J, Gonzalez JP, Zhao Q, Xie LH, Li H, Liu T, Wehrens XH, Lampe PD, Fishman GI, Shirokova N, Contreras JE, Fraidenraich D
The Journal of clinical investigation 2020 Apr 1;130(4):1713-1727
The Journal of clinical investigation 2020 Apr 1;130(4):1713-1727
Secreted protein acidic and rich in cysteine (SPARC) induces epithelial-mesenchymal transition, enhancing migration and invasion, and is associated with high Gleason score in prostate cancer.
López-Moncada F, Torres MJ, Castellón EA, Contreras HR
Asian journal of andrology 2019 Nov-Dec;21(6):557-564
Asian journal of andrology 2019 Nov-Dec;21(6):557-564
Visco-Node-Pore Sensing: A Microfluidic Rheology Platform to Characterize Viscoelastic Properties of Epithelial Cells.
Kim J, Li B, Scheideler OJ, Kim Y, Sohn LL
iScience 2019 Mar 29;13:214-228
iScience 2019 Mar 29;13:214-228
Elevated endothelial Sox2 causes lumen disruption and cerebral arteriovenous malformations.
Yao J, Wu X, Zhang D, Wang L, Zhang L, Reynolds EX, Hernandez C, Boström KI, Yao Y
The Journal of clinical investigation 2019 Jun 24;129(8):3121-3133
The Journal of clinical investigation 2019 Jun 24;129(8):3121-3133
Defining new mechanistic roles for αII spectrin in cardiac function.
Lubbers ER, Murphy NP, Musa H, Huang CY, Gupta R, Price MV, Han M, Daoud E, Gratz D, El Refaey M, Xu X, Hoeflinger NK, Friel EL, Lancione P, Wallace MJ, Cavus O, Simmons SL, Williams JL, Skaf M, Koenig SN, Janssen PML, Rasband MN, Hund TJ, Mohler PJ
The Journal of biological chemistry 2019 Jun 14;294(24):9576-9591
The Journal of biological chemistry 2019 Jun 14;294(24):9576-9591
New Insights into the Role of Polybromo-1 in Prostate Cancer.
Mota STS, Vecchi L, Zóia MAP, Oliveira FM, Alves DA, Dornelas BC, Bezerra SM, Andrade VP, Maia YCP, Neves AF, Goulart LR, Araújo TG
International journal of molecular sciences 2019 Jun 12;20(12)
International journal of molecular sciences 2019 Jun 12;20(12)
Ankyrin-B dysfunction predisposes to arrhythmogenic cardiomyopathy and is amenable to therapy.
Roberts JD, Murphy NP, Hamilton RM, Lubbers ER, James CA, Kline CF, Gollob MH, Krahn AD, Sturm AC, Musa H, El-Refaey M, Koenig S, Aneq MÅ, Hoorntje ET, Graw SL, Davies RW, Rafiq MA, Koopmann TT, Aafaqi S, Fatah M, Chiasson DA, Taylor MR, Simmons SL, Han M, van Opbergen CJ, Wold LE, Sinagra G, Mittal K, Tichnell C, Murray B, Codima A, Nazer B, Nguyen DT, Marcus FI, Sobriera N, Lodder EM, van den Berg MP, Spears DA, Robinson JF, Ursell PC, Green AK, Skanes AC, Tang AS, Gardner MJ, Hegele RA, van Veen TA, Wilde AA, Healey JS, Janssen PM, Mestroni L, van Tintelen JP, Calkins H, Judge DP, Hund TJ, Scheinman MM, Mohler PJ
The Journal of clinical investigation 2019 Jul 2;129(8):3171-3184
The Journal of clinical investigation 2019 Jul 2;129(8):3171-3184
mTORC1/rpS6 signaling complex modifies BTB transport function: an in vivo study using the adjudin model.
Yan M, Li L, Mao B, Li H, Li SYT, Mruk D, Silvestrini B, Lian Q, Ge R, Cheng CY
American journal of physiology. Endocrinology and metabolism 2019 Jul 1;317(1):E121-E138
American journal of physiology. Endocrinology and metabolism 2019 Jul 1;317(1):E121-E138
FGF18, a prominent player in FGF signaling, promotes gastric tumorigenesis through autocrine manner and is negatively regulated by miR-590-5p.
Zhang J, Zhou Y, Huang T, Wu F, Pan Y, Dong Y, Wang Y, Chan AKY, Liu L, Kwan JSH, Cheung AHK, Wong CC, Lo AKF, Cheng ASL, Yu J, Lo KW, Kang W, To KF
Oncogene 2019 Jan;38(1):33-46
Oncogene 2019 Jan;38(1):33-46
Planar cell polarity protein Dishevelled 3 (Dvl3) regulates ectoplasmic specialization (ES) dynamics in the testis through changes in cytoskeletal organization.
Li L, Mao B, Yan M, Wu S, Ge R, Lian Q, Cheng CY
Cell death & disease 2019 Feb 26;10(3):194
Cell death & disease 2019 Feb 26;10(3):194
The N-cadherin interactome in primary cardiomyocytes as defined using quantitative proximity proteomics.
Li Y, Merkel CD, Zeng X, Heier JA, Cantrell PS, Sun M, Stolz DB, Watkins SC, Yates NA, Kwiatkowski AV
Journal of cell science 2019 Feb 11;132(3)
Journal of cell science 2019 Feb 11;132(3)
Ankyrin-G regulated epithelial phenotype is required for mouse lens morphogenesis and growth.
Rasiah PK, Maddala R, Bennett V, Rao PV
Developmental biology 2019 Feb 1;446(1):119-131
Developmental biology 2019 Feb 1;446(1):119-131
Pannexin1 Is Associated with Enhanced Epithelial-To-Mesenchymal Transition in Human Patient Breast Cancer Tissues and in Breast Cancer Cell Lines.
Jalaleddine N, El-Hajjar L, Dakik H, Shaito A, Saliba J, Safi R, Zibara K, El-Sabban M
Cancers 2019 Dec 7;11(12)
Cancers 2019 Dec 7;11(12)
YBX-1 mediated sorting of miR-133 into hypoxia/reoxygenation-induced EPC-derived exosomes to increase fibroblast angiogenesis and MEndoT.
Lin F, Zeng Z, Song Y, Li L, Wu Z, Zhang X, Li Z, Ke X, Hu X
Stem cell research & therapy 2019 Aug 23;10(1):263
Stem cell research & therapy 2019 Aug 23;10(1):263
Modeling the effect of ascites-induced compression on ovarian cancer multicellular aggregates.
Klymenko Y, Wates RB, Weiss-Bilka H, Lombard R, Liu Y, Campbell L, Kim O, Wagner D, Ravosa MJ, Stack MS
Disease models & mechanisms 2018 Sep 25;11(9)
Disease models & mechanisms 2018 Sep 25;11(9)
Differential Wnt-mediated programming and arrhythmogenesis in right versus left ventricles.
Li G, Khandekar A, Yin T, Hicks SC, Guo Q, Takahashi K, Lipovsky CE, Brumback BD, Rao PK, Weinheimer CJ, Rentschler SL
Journal of molecular and cellular cardiology 2018 Oct;123:92-107
Journal of molecular and cellular cardiology 2018 Oct;123:92-107
Dynein 1 supports spermatid transport and spermiation during spermatogenesis in the rat testis.
Wen Q, Tang EI, Lui WY, Lee WM, Wong CKC, Silvestrini B, Cheng CY
American journal of physiology. Endocrinology and metabolism 2018 Nov 1;315(5):E924-E948
American journal of physiology. Endocrinology and metabolism 2018 Nov 1;315(5):E924-E948
SRGAP1, a crucial target of miR-340 and miR-124, functions as a potential oncogene in gastric tumorigenesis.
Huang T, Zhou Y, Zhang J, Wong CC, Li W, Kwan JSH, Yang R, Chan AKY, Dong Y, Wu F, Zhang B, Cheung AHK, Wu WKK, Cheng ASL, Yu J, Wong N, Kang W, To KF
Oncogene 2018 Mar;37(9):1159-1174
Oncogene 2018 Mar;37(9):1159-1174
Matrine inhibits prostate cancer via activation of the unfolded protein response/endoplasmic reticulum stress signaling and reversal of epithelial to mesenchymal transition.
Chang J, Hu S, Wang W, Li Y, Zhi W, Lu S, Shi Q, Wang Y, Yang Y
Molecular medicine reports 2018 Jul;18(1):945-957
Molecular medicine reports 2018 Jul;18(1):945-957
Nitric oxide-sensitive guanylyl cyclase stimulation improves experimental heart failure with preserved ejection fraction.
Wilck N, Markó L, Balogh A, Kräker K, Herse F, Bartolomaeus H, Szijártó IA, Gollasch M, Reichhart N, Strauss O, Heuser A, Brockschnieder D, Kretschmer A, Lesche R, Sohler F, Stasch JP, Sandner P, Luft FC, Müller DN, Dechend R, Haase N
JCI insight 2018 Feb 22;3(4)
JCI insight 2018 Feb 22;3(4)
Actin nucleator Spire 1 is a regulator of ectoplasmic specialization in the testis.
Wen Q, Li N, Xiao X, Lui WY, Chu DS, Wong CKC, Lian Q, Ge R, Lee WM, Silvestrini B, Cheng CY
Cell death & disease 2018 Feb 12;9(2):208
Cell death & disease 2018 Feb 12;9(2):208
Intercalated cushion cells within the cardiac outflow tract are derived from the myocardial troponin T type 2 (Tnnt2) Cre lineage.
Mifflin JJ, Dupuis LE, Alcala NE, Russell LG, Kern CB
Developmental dynamics : an official publication of the American Association of Anatomists 2018 Aug;247(8):1005-1017
Developmental dynamics : an official publication of the American Association of Anatomists 2018 Aug;247(8):1005-1017
Direct Cardiac Reprogramming as a Novel Therapeutic Strategy for Treatment of Myocardial Infarction.
Ma H, Wang L, Liu J, Qian L
Methods in molecular biology (Clifton, N.J.) 2017;1521:69-88
Methods in molecular biology (Clifton, N.J.) 2017;1521:69-88
Cellular inhibitor of apoptosis protein 2 promotes the epithelial-mesenchymal transition in triple-negative breast cancer cells through activation of the AKT signaling pathway.
Jo SJ, Park PG, Cha HR, Ahn SG, Kim MJ, Kim H, Koo JS, Jeong J, Park JH, Dong SM, Lee JM
Oncotarget 2017 Oct 3;8(45):78781-78795
Oncotarget 2017 Oct 3;8(45):78781-78795
Electronic Cigarette Smoke Impairs Normal Mesenchymal Stem Cell Differentiation.
Shaito A, Saliba J, Husari A, El-Harakeh M, Chhouri H, Hashem Y, Shihadeh A, El-Sabban M
Scientific reports 2017 Oct 27;7(1):14281
Scientific reports 2017 Oct 27;7(1):14281
TGF-β1 affects cell-cell adhesion in the heart in an NCAM1-dependent mechanism.
Ackermann MA, Petrosino JM, Manring HR, Wright P, Shettigar V, Kilic A, Janssen PML, Ziolo MT, Accornero F
Journal of molecular and cellular cardiology 2017 Nov;112:49-57
Journal of molecular and cellular cardiology 2017 Nov;112:49-57
Mosaic Analysis with Double Markers Reveals Distinct Sequential Functions of Lgl1 in Neural Stem Cells.
Beattie R, Postiglione MP, Burnett LE, Laukoter S, Streicher C, Pauler FM, Xiao G, Klezovitch O, Vasioukhin V, Ghashghaei TH, Hippenmeyer S
Neuron 2017 May 3;94(3):517-533.e3
Neuron 2017 May 3;94(3):517-533.e3
Mild hypothermia preserves myocardial conduction during ischemia by maintaining gap junction intracellular communication and Na(+) channel function.
Nassal MMJ, Wan X, Dale Z, Deschênes I, Wilson LD, Piktel JS
American journal of physiology. Heart and circulatory physiology 2017 May 1;312(5):H886-H895
American journal of physiology. Heart and circulatory physiology 2017 May 1;312(5):H886-H895
Identification of a Novel Human E-Cadherin Splice Variant and Assessment of Its Effects Upon EMT-Related Events.
Matos ML, Lapyckyj L, Rosso M, Besso MJ, Mencucci MV, Briggiler CI, Giustina S, Furlong LI, Vazquez-Levin MH
Journal of cellular physiology 2017 Jun;232(6):1368-1386
Journal of cellular physiology 2017 Jun;232(6):1368-1386
A Critical Role of Presynaptic Cadherin/Catenin/p140Cap Complexes in Stabilizing Spines and Functional Synapses in the Neocortex.
Li MY, Miao WY, Wu QZ, He SJ, Yan G, Yang Y, Liu JJ, Taketo MM, Yu X
Neuron 2017 Jun 21;94(6):1155-1172.e8
Neuron 2017 Jun 21;94(6):1155-1172.e8
Neurons secrete miR-132-containing exosomes to regulate brain vascular integrity.
Xu B, Zhang Y, Du XF, Li J, Zi HX, Bu JW, Yan Y, Han H, Du JL
Cell research 2017 Jul;27(7):882-897
Cell research 2017 Jul;27(7):882-897
Heterogeneous Cadherin Expression and Multicellular Aggregate Dynamics in Ovarian Cancer Dissemination.
Klymenko Y, Johnson J, Bos B, Lombard R, Campbell L, Loughran E, Stack MS
Neoplasia (New York, N.Y.) 2017 Jul;19(7):549-563
Neoplasia (New York, N.Y.) 2017 Jul;19(7):549-563
Defective CFTR leads to aberrant β-catenin activation and kidney fibrosis.
Zhang JT, Wang Y, Chen JJ, Zhang XH, Dong JD, Tsang LL, Huang XR, Cai Z, Lan HY, Jiang XH, Chan HC
Scientific reports 2017 Jul 12;7(1):5233
Scientific reports 2017 Jul 12;7(1):5233
Intermittent hypoxia causes NOX2-dependent remodeling of atrial connexins.
Gemel J, Su Z, Gileles-Hillel A, Khalyfa A, Gozal D, Beyer EC
BMC cell biology 2017 Jan 17;18(Suppl 1):7
BMC cell biology 2017 Jan 17;18(Suppl 1):7
Proteomic analysis of ovarian cancer cells during epithelial-mesenchymal transition (EMT) induced by epidermal growth factor (EGF) reveals mechanisms of cell cycle control.
Grassi ML, Palma CS, Thomé CH, Lanfredi GP, Poersch A, Faça VM
Journal of proteomics 2017 Jan 16;151:2-11
Journal of proteomics 2017 Jan 16;151:2-11
Decreased WNT/β-catenin signalling contributes to the pathogenesis of dilated cardiomyopathy caused by mutations in the lamin a/C gene.
Le Dour C, Macquart C, Sera F, Homma S, Bonne G, Morrow JP, Worman HJ, Muchir A
Human molecular genetics 2017 Jan 15;26(2):333-343
Human molecular genetics 2017 Jan 15;26(2):333-343
Amplification of R-spondin1 signaling induces granulosa cell fate defects and cancers in mouse adult ovary.
De Cian MC, Pauper E, Bandiera R, Vidal VP, Sacco S, Gregoire EP, Chassot AA, Panzolini C, Wilhelm D, Pailhoux E, Youssef SA, de Bruin A, Teerds K, Schedl A, Gillot I, Chaboissier MC
Oncogene 2017 Jan 12;36(2):208-218
Oncogene 2017 Jan 12;36(2):208-218
Regulation of the blood-testis barrier by a local axis in the testis: role of laminin α2 in the basement membrane.
Gao Y, Mruk D, Chen H, Lui WY, Lee WM, Cheng CY
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 Feb;31(2):584-597
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 Feb;31(2):584-597
MicroRNA-661 modulates redox and metabolic homeostasis in colon cancer.
Gómez de Cedrón M, Acín Pérez R, Sánchez-Martínez R, Molina S, Herranz J, Feliu J, Reglero G, Enríquez JA, Ramírez de Molina A
Molecular oncology 2017 Dec;11(12):1768-1787
Molecular oncology 2017 Dec;11(12):1768-1787
Inhibition of soluble epoxide hydrolase prevents diabetic retinopathy.
Hu J, Dziumbla S, Lin J, Bibli SI, Zukunft S, de Mos J, Awwad K, Frömel T, Jungmann A, Devraj K, Cheng Z, Wang L, Fauser S, Eberhart CG, Sodhi A, Hammock BD, Liebner S, Müller OJ, Glaubitz C, Hammes HP, Popp R, Fleming I
Nature 2017 Dec 14;552(7684):248-252
Nature 2017 Dec 14;552(7684):248-252
Roles of TGFβ and FGF signals during growth and differentiation of mouse lens epithelial cell in vitro.
Wang D, Wang E, Liu K, Xia CH, Li S, Gong X
Scientific reports 2017 Aug 4;7(1):7274
Scientific reports 2017 Aug 4;7(1):7274
Spontaneous acquisition of infinite proliferative capacity by a rabbit corneal endothelial cell line with maintenance of phenotypic and physiological characteristics.
Kageyama T, Hayashi R, Hara S, Yoshikawa K, Ishikawa Y, Yamato M, Nishida K
Journal of tissue engineering and regenerative medicine 2017 Apr;11(4):1057-1064
Journal of tissue engineering and regenerative medicine 2017 Apr;11(4):1057-1064
Perfluorooctanesulfonate (PFOS)-induced Sertoli cell injury through a disruption of F-actin and microtubule organization is mediated by Akt1/2.
Gao Y, Chen H, Xiao X, Lui WY, Lee WM, Mruk DD, Cheng CY
Scientific reports 2017 Apr 24;7(1):1110
Scientific reports 2017 Apr 24;7(1):1110
The Apical Localization of Na(+), K(+)-ATPase in Cultured Human Retinal Pigment Epithelial Cells Depends on Expression of the β(2) Subunit.
Lobato-Álvarez JA, Roldán ML, López-Murillo TD, González-Ramírez R, Bonilla-Delgado J, Shoshani L
Frontiers in physiology 2016;7:450
Frontiers in physiology 2016;7:450
Isolation of an ES-Derived Cardiovascular Multipotent Cell Population Based on VE-Cadherin Promoter Activity.
Maltabe VA, Barka E, Kontonika M, Florou D, Kouvara-Pritsouli M, Roumpi M, Agathopoulos S, Kolettis TM, Kouklis P
Stem cells international 2016;2016:8305624
Stem cells international 2016;2016:8305624
Biased Expression of the FOXP3Δ3 Isoform in Aggressive Bladder Cancer Mediates Differentiation and Cisplatin Chemotherapy Resistance.
Zhang H, Prado K, Zhang KX, Peek EM, Lee J, Wang X, Huang J, Li G, Pellegrini M, Chin AI
Clinical cancer research : an official journal of the American Association for Cancer Research 2016 Nov 1;22(21):5349-5361
Clinical cancer research : an official journal of the American Association for Cancer Research 2016 Nov 1;22(21):5349-5361
Interleukin 1alpha-induced disruption of the Sertoli cell cytoskeleton affects gap junctional communication.
Chojnacka K, Bilinska B, Mruk DD
Cellular signalling 2016 May;28(5):469-480
Cellular signalling 2016 May;28(5):469-480
Planar Cell Polarity (PCP) Protein Vangl2 Regulates Ectoplasmic Specialization Dynamics via Its Effects on Actin Microfilaments in the Testes of Male Rats.
Chen H, Mruk DD, Lee WM, Cheng CY
Endocrinology 2016 May;157(5):2140-59
Endocrinology 2016 May;157(5):2140-59
An epithelial to mesenchymal transition programme does not usually drive the phenotype of invasive lobular carcinomas.
McCart Reed AE, Kutasovic JR, Vargas AC, Jayanthan J, Al-Murrani A, Reid LE, Chambers R, Da Silva L, Melville L, Evans E, Porter A, Papadimos D, Thompson EW, Lakhani SR, Simpson PT
The Journal of pathology 2016 Mar;238(4):489-94
The Journal of pathology 2016 Mar;238(4):489-94
Specific deletion of AMP-activated protein kinase (α1AMPK) in mouse Sertoli cells modifies germ cell quality.
Bertoldo MJ, Guibert E, Faure M, Guillou F, Ramé C, Nadal-Desbarats L, Foretz M, Viollet B, Dupont J, Froment P
Molecular and cellular endocrinology 2016 Mar 5;423:96-112
Molecular and cellular endocrinology 2016 Mar 5;423:96-112
Polarity protein Crumbs homolog-3 (CRB3) regulates ectoplasmic specialization dynamics through its action on F-actin organization in Sertoli cells.
Gao Y, Lui WY, Lee WM, Cheng CY
Scientific reports 2016 Jun 30;6:28589
Scientific reports 2016 Jun 30;6:28589
Rescue of perfluorooctanesulfonate (PFOS)-mediated Sertoli cell injury by overexpression of gap junction protein connexin 43.
Li N, Mruk DD, Chen H, Wong CK, Lee WM, Cheng CY
Scientific reports 2016 Jul 20;6:29667
Scientific reports 2016 Jul 20;6:29667
Phosphorylation at Connexin43 Serine-368 Is Necessary for Myocardial Conduction During Metabolic Stress.
Nassal MM, Werdich AA, Wan X, Hoshi M, Deschênes I, Rosenbaum DS, Donahue JK
Journal of cardiovascular electrophysiology 2016 Jan;27(1):110-9
Journal of cardiovascular electrophysiology 2016 Jan;27(1):110-9
The CaSm (LSm1) oncogene promotes transformation, chemoresistance and metastasis of pancreatic cancer cells.
Little EC, Camp ER, Wang C, Watson PM, Watson DK, Cole DJ
Oncogenesis 2016 Jan 11;5(1):e182
Oncogenesis 2016 Jan 11;5(1):e182
Cell coupling mediated by connexin 26 selectively contributes to reduced adhesivity and increased migration.
Polusani SR, Kalmykov EA, Chandrasekhar A, Zucker SN, Nicholson BJ
Journal of cell science 2016 Dec 1;129(23):4399-4410
Journal of cell science 2016 Dec 1;129(23):4399-4410
Overexpression of plastin 3 in Sertoli cells disrupts actin microfilament bundle homeostasis and perturbs the tight junction barrier.
Li N, Lee WM, Cheng CY
Spermatogenesis 2016 Apr;6(1):e1206353
Spermatogenesis 2016 Apr;6(1):e1206353
Connexin 43 reboots meiosis and reseals blood-testis barrier following toxicant-mediated aspermatogenesis and barrier disruption.
Li N, Mruk DD, Mok KW, Li MW, Wong CK, Lee WM, Han D, Silvestrini B, Cheng CY
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2016 Apr;30(4):1436-52
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2016 Apr;30(4):1436-52
Two-Pore K+ Channel TREK-1 Regulates Sinoatrial Node Membrane Excitability.
Unudurthi SD, Wu X, Qian L, Amari F, Onal B, Li N, Makara MA, Smith SA, Snyder J, Fedorov VV, Coppola V, Anderson ME, Mohler PJ, Hund TJ
Journal of the American Heart Association 2016 Apr 20;5(4):e002865
Journal of the American Heart Association 2016 Apr 20;5(4):e002865
Fibroblast growth factor receptor 2 (FGFR2) is required for corneal epithelial cell proliferation and differentiation during embryonic development.
Zhang J, Upadhya D, Lu L, Reneker LW
PloS one 2015;10(1):e0117089
PloS one 2015;10(1):e0117089
Actin-bundling protein plastin 3 is a regulator of ectoplasmic specialization dynamics during spermatogenesis in the rat testis.
Li N, Mruk DD, Wong CK, Lee WM, Han D, Cheng CY
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2015 Sep;29(9):3788-805
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2015 Sep;29(9):3788-805
Characterization of the equine blood-testis barrier during tubular development in normal and cryptorchid stallions.
Rode K, Sieme H, Richterich P, Brehm R
Theriogenology 2015 Sep 15;84(5):763-72
Theriogenology 2015 Sep 15;84(5):763-72
Serine Protease Activation Essential for Endothelial-Mesenchymal Transition in Vascular Calcification.
Yao J, Guihard PJ, Blazquez-Medela AM, Guo Y, Moon JH, Jumabay M, Boström KI, Yao Y
Circulation research 2015 Oct 9;117(9):758-69
Circulation research 2015 Oct 9;117(9):758-69
Cardiomyocyte-specific overexpression of the ubiquitin ligase Wwp1 contributes to reduction in Connexin 43 and arrhythmogenesis.
Basheer WA, Harris BS, Mentrup HL, Abreha M, Thames EL, Lea JB, Swing DA, Copeland NG, Jenkins NA, Price RL, Matesic LE
Journal of molecular and cellular cardiology 2015 Nov;88:1-13
Journal of molecular and cellular cardiology 2015 Nov;88:1-13
Defective autophagy is a key feature of cerebral cavernous malformations.
Marchi S, Corricelli M, Trapani E, Bravi L, Pittaro A, Delle Monache S, Ferroni L, Patergnani S, Missiroli S, Goitre L, Trabalzini L, Rimessi A, Giorgi C, Zavan B, Cassoni P, Dejana E, Retta SF, Pinton P
EMBO molecular medicine 2015 Nov;7(11):1403-17
EMBO molecular medicine 2015 Nov;7(11):1403-17
ESRP2 controls an adult splicing programme in hepatocytes to support postnatal liver maturation.
Bhate A, Parker DJ, Bebee TW, Ahn J, Arif W, Rashan EH, Chorghade S, Chau A, Lee JH, Anakk S, Carstens RP, Xiao X, Kalsotra A
Nature communications 2015 Nov 4;6:8768
Nature communications 2015 Nov 4;6:8768
Heterogeneity between triple negative breast cancer cells due to differential activation of Wnt and PI3K/AKT pathways.
Martínez-Revollar G, Garay E, Martin-Tapia D, Nava P, Huerta M, Lopez-Bayghen E, Meraz-Cruz N, Segovia J, González-Mariscal L
Experimental cell research 2015 Nov 15;339(1):67-80
Experimental cell research 2015 Nov 15;339(1):67-80
Flutamide alters the distribution of c-Src and affects the N-cadherin-β-catenin complex in the seminiferous epithelium of adult rat.
Zarzycka M, Chojnacka K, Mruk DD, Gorowska E, Hejmej A, Kotula-Balak M, Pardyak L, Bilinska B
Andrology 2015 May;3(3):569-81
Andrology 2015 May;3(3):569-81
miR-200c/Bmi1 axis and epithelial-mesenchymal transition contribute to acquired resistance to BRAF inhibitor treatment.
Liu S, Tetzlaff MT, Wang T, Yang R, Xie L, Zhang G, Krepler C, Xiao M, Beqiri M, Xu W, Karakousis G, Schuchter L, Amaravadi RK, Xu W, Wei Z, Herlyn M, Yao Y, Zhang L, Wang Y, Zhang L, Xu X
Pigment cell & melanoma research 2015 Jul;28(4):431-41
Pigment cell & melanoma research 2015 Jul;28(4):431-41
Loss of ATM accelerates pancreatic cancer formation and epithelial-mesenchymal transition.
Russell R, Perkhofer L, Liebau S, Lin Q, Lechel A, Feld FM, Hessmann E, Gaedcke J, Güthle M, Zenke M, Hartmann D, von Figura G, Weissinger SE, Rudolph KL, Möller P, Lennerz JK, Seufferlein T, Wagner M, Kleger A
Nature communications 2015 Jul 29;6:7677
Nature communications 2015 Jul 29;6:7677
Expression of miR-200c in claudin-low breast cancer alters stem cell functionality, enhances chemosensitivity and reduces metastatic potential.
Knezevic J, Pfefferle AD, Petrovic I, Greene SB, Perou CM, Rosen JM
Oncogene 2015 Dec 3;34(49):5997-6006
Oncogene 2015 Dec 3;34(49):5997-6006
Platelets enhance tissue factor protein and metastasis initiating cell markers, and act as chemoattractants increasing the migration of ovarian cancer cells.
Orellana R, Kato S, Erices R, Bravo ML, Gonzalez P, Oliva B, Cubillos S, Valdivia A, Ibañez C, Brañes J, Barriga MI, Bravo E, Alonso C, Bustamente E, Castellon E, Hidalgo P, Trigo C, Panes O, Pereira J, Mezzano D, Cuello MA, Owen GI
BMC cancer 2015 Apr 15;15:290
BMC cancer 2015 Apr 15;15:290
Cdk5-mediated phosphorylation of RapGEF2 controls neuronal migration in the developing cerebral cortex.
Ye T, Ip JP, Fu AK, Ip NY
Nature communications 2014 Sep 5;5:4826
Nature communications 2014 Sep 5;5:4826
Dlg5 regulates dendritic spine formation and synaptogenesis by controlling subcellular N-cadherin localization.
Wang SH, Celic I, Choi SY, Riccomagno M, Wang Q, Sun LO, Mitchell SP, Vasioukhin V, Huganir RL, Kolodkin AL
The Journal of neuroscience : the official journal of the Society for Neuroscience 2014 Sep 17;34(38):12745-61
The Journal of neuroscience : the official journal of the Society for Neuroscience 2014 Sep 17;34(38):12745-61
HNF4α induced chemosensitivity to oxaliplatin and 5-FU mediated by OCT1 and CNT3 in renal cell carcinoma.
Hagos Y, Wegner W, Kuehne A, Floerl S, Marada VV, Burckhardt G, Henjakovic M
Journal of pharmaceutical sciences 2014 Oct;103(10):3326-34
Journal of pharmaceutical sciences 2014 Oct;103(10):3326-34
Connexin40 abnormalities and atrial fibrillation in the human heart.
Gemel J, Levy AE, Simon AR, Bennett KB, Ai X, Akhter S, Beyer EC
Journal of molecular and cellular cardiology 2014 Nov;76:159-68
Journal of molecular and cellular cardiology 2014 Nov;76:159-68
rpS6 regulates blood-testis barrier dynamics through Akt-mediated effects on MMP-9.
Mok KW, Mruk DD, Cheng CY
Journal of cell science 2014 Nov 15;127(Pt 22):4870-82
Journal of cell science 2014 Nov 15;127(Pt 22):4870-82
TRPV2 is critical for the maintenance of cardiac structure and function in mice.
Katanosaka Y, Iwasaki K, Ujihara Y, Takatsu S, Nishitsuji K, Kanagawa M, Sudo A, Toda T, Katanosaka K, Mohri S, Naruse K
Nature communications 2014 May 29;5:3932
Nature communications 2014 May 29;5:3932
14-3-3γ-Mediated transport of plakoglobin to the cell border is required for the initiation of desmosome assembly in vitro and in vivo.
Sehgal L, Mukhopadhyay A, Rajan A, Khapare N, Sawant M, Vishal SS, Bhatt K, Ambatipudi S, Antao N, Alam H, Gurjar M, Basu S, Mathur R, Borde L, Hosing AS, Vaidya MM, Thorat R, Samaniego F, Kolthur-Seetharam U, Dalal SN
Journal of cell science 2014 May 15;127(Pt 10):2174-88
Journal of cell science 2014 May 15;127(Pt 10):2174-88
LIM-homeobox gene 2 promotes tumor growth and metastasis by inducing autocrine and paracrine PDGF-B signaling.
Kuzmanov A, Hopfer U, Marti P, Meyer-Schaller N, Yilmaz M, Christofori G
Molecular oncology 2014 Mar;8(2):401-16
Molecular oncology 2014 Mar;8(2):401-16
VEGF-mediated angiogenesis links EMT-induced cancer stemness to tumor initiation.
Fantozzi A, Gruber DC, Pisarsky L, Heck C, Kunita A, Yilmaz M, Meyer-Schaller N, Cornille K, Hopfer U, Bentires-Alj M, Christofori G
Cancer research 2014 Mar 1;74(5):1566-75
Cancer research 2014 Mar 1;74(5):1566-75
Environmental toxicants perturb human Sertoli cell adhesive function via changes in F-actin organization mediated by actin regulatory proteins.
Xiao X, Mruk DD, Tang EI, Wong CK, Lee WM, John CM, Turek PJ, Silvestrini B, Cheng CY
Human reproduction (Oxford, England) 2014 Jun;29(6):1279-91
Human reproduction (Oxford, England) 2014 Jun;29(6):1279-91
Calpain-dependent cleavage of N-cadherin is involved in the progression of post-myocardial infarction remodeling.
Kudo-Sakamoto Y, Akazawa H, Ito K, Takano J, Yano M, Yabumoto C, Naito AT, Oka T, Lee JK, Sakata Y, Suzuki J, Saido TC, Komuro I
The Journal of biological chemistry 2014 Jul 11;289(28):19408-19
The Journal of biological chemistry 2014 Jul 11;289(28):19408-19
Perfluorooctanesulfonate (PFOS) perturbs male rat Sertoli cell blood-testis barrier function by affecting F-actin organization via p-FAK-Tyr(407): an in vitro study.
Wan HT, Mruk DD, Wong CK, Cheng CY
Endocrinology 2014 Jan;155(1):249-62
Endocrinology 2014 Jan;155(1):249-62
Novel three-dimensional in vitro models of ovarian endometriosis.
Brueggmann D, Templeman C, Starzinski-Powitz A, Rao NP, Gayther SA, Lawrenson K
Journal of ovarian research 2014 Feb 6;7:17
Journal of ovarian research 2014 Feb 6;7:17
Isolation and characterization of a primary proximal tubular epithelial cell model from human kidney by CD10/CD13 double labeling.
Van der Hauwaert C, Savary G, Gnemmi V, Glowacki F, Pottier N, Bouillez A, Maboudou P, Zini L, Leroy X, Cauffiez C, Perrais M, Aubert S
PloS one 2013;8(6):e66750
PloS one 2013;8(6):e66750
Rai14 (retinoic acid induced protein 14) is involved in regulating f-actin dynamics at the ectoplasmic specialization in the rat testis*.
Qian X, Mruk DD, Cheng CY
PloS one 2013;8(4):e60656
PloS one 2013;8(4):e60656
Toward a molecular pathologic classification of urothelial carcinoma.
Sjödahl G, Lövgren K, Lauss M, Patschan O, Gudjonsson S, Chebil G, Aine M, Eriksson P, Månsson W, Lindgren D, Fernö M, Liedberg F, Höglund M
The American journal of pathology 2013 Sep;183(3):681-91
The American journal of pathology 2013 Sep;183(3):681-91
Three-dimensional cell culturing by magnetic levitation.
Haisler WL, Timm DM, Gage JA, Tseng H, Killian TC, Souza GR
Nature protocols 2013 Oct;8(10):1940-9
Nature protocols 2013 Oct;8(10):1940-9
A three-dimensional microenvironment alters protein expression and chemosensitivity of epithelial ovarian cancer cells in vitro.
Lee JM, Mhawech-Fauceglia P, Lee N, Parsanian LC, Lin YG, Gayther SA, Lawrenson K
Laboratory investigation; a journal of technical methods and pathology 2013 May;93(5):528-42
Laboratory investigation; a journal of technical methods and pathology 2013 May;93(5):528-42
Palladin is a regulator of actin filament bundles at the ectoplasmic specialization in adult rat testes.
Qian X, Mruk DD, Wong EW, Lie PP, Cheng CY
Endocrinology 2013 May;154(5):1907-20
Endocrinology 2013 May;154(5):1907-20
The Meckel syndrome protein meckelin (TMEM67) is a key regulator of cilia function but is not required for tissue planar polarity.
Leightner AC, Hommerding CJ, Peng Y, Salisbury JL, Gainullin VG, Czarnecki PG, Sussman CR, Harris PC
Human molecular genetics 2013 May 15;22(10):2024-40
Human molecular genetics 2013 May 15;22(10):2024-40
The Xin repeat-containing protein, mXinβ, initiates the maturation of the intercalated discs during postnatal heart development.
Wang Q, Lin JL, Chan SY, Lin JJ
Developmental biology 2013 Feb 15;374(2):264-80
Developmental biology 2013 Feb 15;374(2):264-80
The p63 protein isoform ΔNp63α inhibits epithelial-mesenchymal transition in human bladder cancer cells: role of MIR-205.
Tran MN, Choi W, Wszolek MF, Navai N, Lee IL, Nitti G, Wen S, Flores ER, Siefker-Radtke A, Czerniak B, Dinney C, Barton M, McConkey DJ
The Journal of biological chemistry 2013 Feb 1;288(5):3275-88
The Journal of biological chemistry 2013 Feb 1;288(5):3275-88
Generation of a human airway epithelium derived basal cell line with multipotent differentiation capacity.
Walters MS, Gomi K, Ashbridge B, Moore MA, Arbelaez V, Heldrich J, Ding BS, Rafii S, Staudt MR, Crystal RG
Respiratory research 2013 Dec 3;14(1):135
Respiratory research 2013 Dec 3;14(1):135
Further evidence that E-cadherin is not a tumour suppressor gene in invasive ductal carcinoma of the breast: an immunohistochemical study.
Rakha EA, Teoh TK, Lee AH, Nolan CC, Ellis IO, Green AR
Histopathology 2013 Apr;62(5):695-701
Histopathology 2013 Apr;62(5):695-701
Cardiovascular dysregulation of miR-17-92 causes a lethal hypertrophic cardiomyopathy and arrhythmogenesis.
Danielson LS, Park DS, Rotllan N, Chamorro-Jorganes A, Guijarro MV, Fernandez-Hernando C, Fishman GI, Phoon CK, Hernando E
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2013 Apr;27(4):1460-7
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2013 Apr;27(4):1460-7
N-cadherin in neuroblastoma disease: expression and clinical significance.
Lammens T, Swerts K, Derycke L, De Craemer A, De Brouwer S, De Preter K, Van Roy N, Vandesompele J, Speleman F, Philippé J, Benoit Y, Beiske K, Bracke M, Laureys G
PloS one 2012;7(2):e31206
PloS one 2012;7(2):e31206
Analysis of a Jup hypomorphic allele reveals a critical threshold for postnatal viability.
Swope D, Li J, Muller EJ, Radice GL
Genesis (New York, N.Y. : 2000) 2012 Oct;50(10):717-27
Genesis (New York, N.Y. : 2000) 2012 Oct;50(10):717-27
Loss of cadherin-binding proteins β-catenin and plakoglobin in the heart leads to gap junction remodeling and arrhythmogenesis.
Swope D, Cheng L, Gao E, Li J, Radice GL
Molecular and cellular biology 2012 Mar;32(6):1056-67
Molecular and cellular biology 2012 Mar;32(6):1056-67
Cadherin-11 contributes to pulmonary fibrosis: potential role in TGF-β production and epithelial to mesenchymal transition.
Schneider DJ, Wu M, Le TT, Cho SH, Brenner MB, Blackburn MR, Agarwal SK
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2012 Feb;26(2):503-12
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2012 Feb;26(2):503-12
Immunohistochemical study of the epithelial-mesenchymal transition phenotype in cancer of unknown primary: incidence, correlations and prognostic utility.
Stoyianni A, Goussia A, Pentheroudakis G, Siozopoulou V, Ioachim E, Krikelis D, Golfinopoulos V, Cervantes A, Bobos M, Fotsis T, Bellou S, Fountzilas G, Malamou-Mitsi V, Pavlidis N
Anticancer research 2012 Apr;32(4):1273-81
Anticancer research 2012 Apr;32(4):1273-81
Regulation of retinal progenitor expansion by Frizzled receptors: implications for microphthalmia and retinal coloboma.
Liu C, Bakeri H, Li T, Swaroop A
Human molecular genetics 2012 Apr 15;21(8):1848-60
Human molecular genetics 2012 Apr 15;21(8):1848-60
Microtubule affinity-regulating kinase 4 (MARK4) is a component of the ectoplasmic specialization in the rat testis.
Tang EI, Xiao X, Mruk DD, Qian XJ, Mok KW, Jenardhanan P, Lee WM, Mathur PP, Cheng CY
Spermatogenesis 2012 Apr 1;2(2):117-126
Spermatogenesis 2012 Apr 1;2(2):117-126
Alterations of epithelial stem cell marker patterns in human diabetic corneas and effects of c-met gene therapy.
Saghizadeh M, Soleymani S, Harounian A, Bhakta B, Troyanovsky SM, Brunken WJ, Pellegrini G, Ljubimov AV
Molecular vision 2011;17:2177-90
Molecular vision 2011;17:2177-90
A novel gelatin hydrogel carrier sheet for corneal endothelial transplantation.
Watanabe R, Hayashi R, Kimura Y, Tanaka Y, Kageyama T, Hara S, Tabata Y, Nishida K
Tissue engineering. Part A 2011 Sep;17(17-18):2213-9
Tissue engineering. Part A 2011 Sep;17(17-18):2213-9
Adipose tissue-derived stem cell in vitro differentiation in a three-dimensional dental bud structure.
Ferro F, Spelat R, Falini G, Gallelli A, D'Aurizio F, Puppato E, Pandolfi M, Beltrami AP, Cesselli D, Beltrami CA, Ambesi-Impiombato FS, Curcio F
The American journal of pathology 2011 May;178(5):2299-310
The American journal of pathology 2011 May;178(5):2299-310
Cardiac tissue-restricted deletion of plakoglobin results in progressive cardiomyopathy and activation of {beta}-catenin signaling.
Li J, Swope D, Raess N, Cheng L, Muller EJ, Radice GL
Molecular and cellular biology 2011 Mar;31(6):1134-44
Molecular and cellular biology 2011 Mar;31(6):1134-44
EH-myomesin splice isoform is a novel marker for dilated cardiomyopathy.
Schoenauer R, Emmert MY, Felley A, Ehler E, Brokopp C, Weber B, Nemir M, Faggian GG, Pedrazzini T, Falk V, Hoerstrup SP, Agarkova I
Basic research in cardiology 2011 Mar;106(2):233-47
Basic research in cardiology 2011 Mar;106(2):233-47
ZO-1 determines adherens and gap junction localization at intercalated disks.
Palatinus JA, O'Quinn MP, Barker RJ, Harris BS, Jourdan J, Gourdie RG
American journal of physiology. Heart and circulatory physiology 2011 Feb;300(2):H583-94
American journal of physiology. Heart and circulatory physiology 2011 Feb;300(2):H583-94
E/N-cadherin switch mediates cancer progression via TGF-β-induced epithelial-to-mesenchymal transition in extrahepatic cholangiocarcinoma.
Araki K, Shimura T, Suzuki H, Tsutsumi S, Wada W, Yajima T, Kobayahi T, Kubo N, Kuwano H
British journal of cancer 2011 Dec 6;105(12):1885-93
British journal of cancer 2011 Dec 6;105(12):1885-93
Rac1 GTPase-deficient mouse lens exhibits defects in shape, suture formation, fiber cell migration and survival.
Maddala R, Chauhan BK, Walker C, Zheng Y, Robinson ML, Lang RA, Rao PV
Developmental biology 2011 Dec 1;360(1):30-43
Developmental biology 2011 Dec 1;360(1):30-43
Interleukin-1alpha is a regulator of the blood-testis barrier.
Lie PP, Cheng CY, Mruk DD
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2011 Apr;25(4):1244-53
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2011 Apr;25(4):1244-53
Deletion of p120-catenin results in a tumor microenvironment with inflammation and cancer that establishes it as a tumor suppressor gene.
Stairs DB, Bayne LJ, Rhoades B, Vega ME, Waldron TJ, Kalabis J, Klein-Szanto A, Lee JS, Katz JP, Diehl JA, Reynolds AB, Vonderheide RH, Rustgi AK
Cancer cell 2011 Apr 12;19(4):470-83
Cancer cell 2011 Apr 12;19(4):470-83
Granzyme B is expressed in urothelial carcinoma and promotes cancer cell invasion.
D'Eliseo D, Pisu P, Romano C, Tubaro A, De Nunzio C, Morrone S, Santoni A, Stoppacciaro A, Velotti F
International journal of cancer 2010 Sep 1;127(6):1283-94
International journal of cancer 2010 Sep 1;127(6):1283-94
Differential effects of testosterone and TGF-β3 on endocytic vesicle-mediated protein trafficking events at the blood-testis barrier.
Su L, Mruk DD, Lee WM, Cheng CY
Experimental cell research 2010 Oct 15;316(17):2945-60
Experimental cell research 2010 Oct 15;316(17):2945-60
Adjudin-mediated Sertoli-germ cell junction disassembly affects Sertoli cell barrier function in vitro and in vivo.
Su L, Cheng CY, Mruk DD
The international journal of biochemistry & cell biology 2010 Nov;42(11):1864-75
The international journal of biochemistry & cell biology 2010 Nov;42(11):1864-75
Insights from a desmoplakin mutation identified in lethal acantholytic epidermolysis bullosa.
Hobbs RP, Han SY, van der Zwaag PA, Bolling MC, Jongbloed JD, Jonkman MF, Getsios S, Paller AS, Green KJ
The Journal of investigative dermatology 2010 Nov;130(11):2680-3
The Journal of investigative dermatology 2010 Nov;130(11):2680-3
Expression analysis of epithelial cadherin and related proteins in IBH-6 and IBH-4 human breast cancer cell lines.
Lapyckyj L, Castillo LF, Matos ML, Gabrielli NM, Lüthy IA, Vazquez-Levin MH
Journal of cellular physiology 2010 Mar;222(3):596-605
Journal of cellular physiology 2010 Mar;222(3):596-605
Neural cadherin is expressed in human gametes and participates in sperm-oocyte interaction events.
Marín-Briggiler CI, Lapyckyj L, González Echeverría MF, Rawe VY, Alvarez Sedó C, Vazquez-Levin MH
International journal of andrology 2010 Feb;33(1):e228-39
International journal of andrology 2010 Feb;33(1):e228-39
Variable expression of tenascin-C, osteopontin and fibronectin in inflammatory myofibroblastic tumour of the lung.
Kaarteenaho R, Sormunen R, Pääkkö P
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2010 Feb;118(2):91-100
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2010 Feb;118(2):91-100
Monoclonal antibody targeting of N-cadherin inhibits prostate cancer growth, metastasis and castration resistance.
Tanaka H, Kono E, Tran CP, Miyazaki H, Yamashiro J, Shimomura T, Fazli L, Wada R, Huang J, Vessella RL, An J, Horvath S, Gleave M, Rettig MB, Wainberg ZA, Reiter RE
Nature medicine 2010 Dec;16(12):1414-20
Nature medicine 2010 Dec;16(12):1414-20
The canonical NF-kappaB pathway governs mammary tumorigenesis in transgenic mice and tumor stem cell expansion.
Liu M, Sakamaki T, Casimiro MC, Willmarth NE, Quong AA, Ju X, Ojeifo J, Jiao X, Yeow WS, Katiyar S, Shirley LA, Joyce D, Lisanti MP, Albanese C, Pestell RG
Cancer research 2010 Dec 15;70(24):10464-73
Cancer research 2010 Dec 15;70(24):10464-73
Exploring the peritoneal surface malignancy phenotype--a pilot immunohistochemical study of human pseudomyxoma peritonei and derived animal models.
Flatmark K, Davidson B, Kristian A, Stavnes HT, Førsund M, Reed W
Human pathology 2010 Aug;41(8):1109-19
Human pathology 2010 Aug;41(8):1109-19
Epigenetic programming of mu-opioid receptor gene in mouse brain is regulated by MeCP2 and Brg1 chromatin remodelling factor.
Hwang CK, Song KY, Kim CS, Choi HS, Guo XH, Law PY, Wei LN, Loh HH
Journal of cellular and molecular medicine 2009 Sep;13(9B):3591-615
Journal of cellular and molecular medicine 2009 Sep;13(9B):3591-615
N-cadherin in the maintenance of human corneal limbal epithelial progenitor cells in vitro.
Higa K, Shimmura S, Miyashita H, Kato N, Ogawa Y, Kawakita T, Shimazaki J, Tsubota K
Investigative ophthalmology & visual science 2009 Oct;50(10):4640-5
Investigative ophthalmology & visual science 2009 Oct;50(10):4640-5
The expression of Twist has an impact on survival in human bladder cancer and is influenced by the smoking status.
Fondrevelle ME, Kantelip B, Reiter RE, Chopin DK, Thiery JP, Monnien F, Bittard H, Wallerand H
Urologic oncology 2009 May-Jun;27(3):268-76
Urologic oncology 2009 May-Jun;27(3):268-76
RAB13 participates in ectoplasmic specialization dynamics in the rat testis.
Mruk DD, Lau AS
Biology of reproduction 2009 Mar;80(3):590-601
Biology of reproduction 2009 Mar;80(3):590-601
N-cadherin serves as diagnostic biomarker in intrahepatic and perihilar cholangiocarcinomas.
Mosnier JF, Kandel C, Cazals-Hatem D, Bou-Hanna C, Gournay J, Jarry A, Laboisse CL
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2009 Feb;22(2):182-90
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2009 Feb;22(2):182-90
Slit2 inhibits glioma cell invasion in the brain by suppression of Cdc42 activity.
Yiin JJ, Hu B, Jarzynka MJ, Feng H, Liu KW, Wu JY, Ma HI, Cheng SY
Neuro-oncology 2009 Dec;11(6):779-89
Neuro-oncology 2009 Dec;11(6):779-89
Expressing connexin 43 in breast cancer cells reduces their metastasis to lungs.
Li Z, Zhou Z, Welch DR, Donahue HJ
Clinical & experimental metastasis 2008;25(8):893-901
Clinical & experimental metastasis 2008;25(8):893-901
Phenotypic plasticity of neoplastic ovarian epithelium: unique cadherin profiles in tumor progression.
Hudson LG, Zeineldin R, Stack MS
Clinical & experimental metastasis 2008;25(6):643-55
Clinical & experimental metastasis 2008;25(6):643-55
N-cadherin haploinsufficiency affects cardiac gap junctions and arrhythmic susceptibility.
Li J, Levin MD, Xiong Y, Petrenko N, Patel VV, Radice GL
Journal of molecular and cellular cardiology 2008 Mar;44(3):597-606
Journal of molecular and cellular cardiology 2008 Mar;44(3):597-606
Temporal and spatial localization of nectin-1 and l-afadin during synaptogenesis in hippocampal neurons.
Lim ST, Lim KC, Giuliano RE, Federoff HJ
The Journal of comparative neurology 2008 Mar 10;507(2):1228-44
The Journal of comparative neurology 2008 Mar 10;507(2):1228-44
Blood-testis barrier dynamics are regulated by testosterone and cytokines via their differential effects on the kinetics of protein endocytosis and recycling in Sertoli cells.
Yan HH, Mruk DD, Lee WM, Cheng CY
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008 Jun;22(6):1945-59
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008 Jun;22(6):1945-59
JNK signaling pathway is required for bFGF-mediated surface cadherin downregulation on HUVEC.
Wu JC, Yan HC, Chen WT, Chen WH, Wang CJ, Chi YC, Kao WY
Experimental cell research 2008 Feb 1;314(3):421-9
Experimental cell research 2008 Feb 1;314(3):421-9
Coexpression of two mesenchymal cadherins, cadherin 11 and N-cadherin, on murine fibroblast-like synoviocytes.
Agarwal SK, Lee DM, Kiener HP, Brenner MB
Arthritis and rheumatism 2008 Apr;58(4):1044-54
Arthritis and rheumatism 2008 Apr;58(4):1044-54
Rab4A GTPase catenin interactions are involved in cell junction dynamics in the testis.
Mruk DD, Lau AS, Sarkar O, Xia W
Journal of andrology 2007 Sep-Oct;28(5):742-54
Journal of andrology 2007 Sep-Oct;28(5):742-54
Paucity of pericytes in germinal matrix vasculature of premature infants.
Braun A, Xu H, Hu F, Kocherlakota P, Siegel D, Chander P, Ungvari Z, Csiszar A, Nedergaard M, Ballabh P
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007 Oct 31;27(44):12012-24
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007 Oct 31;27(44):12012-24
IQ-domain GTPase-activating protein 1 regulates beta-catenin at membrane ruffles and its role in macropinocytosis of N-cadherin and adenomatous polyposis coli.
Sharma M, Henderson BR
The Journal of biological chemistry 2007 Mar 16;282(11):8545-56
The Journal of biological chemistry 2007 Mar 16;282(11):8545-56
Evidence of endogenous mu opioid receptor regulation by epigenetic control of the promoters.
Hwang CK, Song KY, Kim CS, Choi HS, Guo XH, Law PY, Wei LN, Loh HH
Molecular and cellular biology 2007 Jul;27(13):4720-36
Molecular and cellular biology 2007 Jul;27(13):4720-36
Bin1 ablation in mammary gland delays tissue remodeling and drives cancer progression.
Chang MY, Boulden J, Sutanto-Ward E, Duhadaway JB, Soler AP, Muller AJ, Prendergast GC
Cancer research 2007 Jan 1;67(1):100-7
Cancer research 2007 Jan 1;67(1):100-7
Foxe3 is required for morphogenesis and differentiation of the anterior segment of the eye and is sensitive to Pax6 gene dosage.
Blixt A, Landgren H, Johansson BR, Carlsson P
Developmental biology 2007 Feb 1;302(1):218-29
Developmental biology 2007 Feb 1;302(1):218-29
Aconitine alters connexin43 phosphorylation status and [Ca2+] oscillation patterns in cultured ventricular myocytes of neonatal rats.
Zhang SW, Liu Y, Huang GZ, Liu L
Toxicology in vitro : an international journal published in association with BIBRA 2007 Dec;21(8):1476-85
Toxicology in vitro : an international journal published in association with BIBRA 2007 Dec;21(8):1476-85
Coxsackie and adenovirus receptor (CAR) is a product of Sertoli and germ cells in rat testes which is localized at the Sertoli-Sertoli and Sertoli-germ cell interface.
Wang CQ, Mruk DD, Lee WM, Cheng CY
Experimental cell research 2007 Apr 15;313(7):1373-92
Experimental cell research 2007 Apr 15;313(7):1373-92
Genetic profiling of epithelial cells expressing E-cadherin repressors reveals a distinct role for Snail, Slug, and E47 factors in epithelial-mesenchymal transition.
Moreno-Bueno G, Cubillo E, Sarrió D, Peinado H, Rodríguez-Pinilla SM, Villa S, Bolós V, Jordá M, Fabra A, Portillo F, Palacios J, Cano A
Cancer research 2006 Oct 1;66(19):9543-56
Cancer research 2006 Oct 1;66(19):9543-56
N-cadherin as a novel prognostic marker of progression in superficial urothelial tumors.
Lascombe I, Clairotte A, Fauconnet S, Bernardini S, Wallerand H, Kantelip B, Bittard H
Clinical cancer research : an official journal of the American Association for Cancer Research 2006 May 1;12(9):2780-7
Clinical cancer research : an official journal of the American Association for Cancer Research 2006 May 1;12(9):2780-7
Laminin alpha 3 forms a complex with beta3 and gamma3 chains that serves as the ligand for alpha 6beta1-integrin at the apical ectoplasmic specialization in adult rat testes.
Yan HHN, Cheng CY
The Journal of biological chemistry 2006 Jun 23;281(25):17286-17303
The Journal of biological chemistry 2006 Jun 23;281(25):17286-17303
Adjudin-mediated junction restructuring in the seminiferous epithelium leads to displacement of soluble guanylate cyclase from adherens junctions.
Sarkar O, Xia W, Mruk DD
Journal of cellular physiology 2006 Jul;208(1):175-87
Journal of cellular physiology 2006 Jul;208(1):175-87
Dynamin II interacts with the cadherin- and occludin-based protein complexes at the blood-testis barrier in adult rat testes.
Lie PP, Xia W, Wang CQ, Mruk DD, Yan HH, Wong CH, Lee WM, Cheng CY
The Journal of endocrinology 2006 Dec;191(3):571-86
The Journal of endocrinology 2006 Dec;191(3):571-86
Notch1 signaling promotes primary melanoma progression by activating mitogen-activated protein kinase/phosphatidylinositol 3-kinase-Akt pathways and up-regulating N-cadherin expression.
Liu ZJ, Xiao M, Balint K, Smalley KS, Brafford P, Qiu R, Pinnix CC, Li X, Herlyn M
Cancer research 2006 Apr 15;66(8):4182-90
Cancer research 2006 Apr 15;66(8):4182-90
Molecular characterization of tumour heterogeneity and malignant mesothelioma cell differentiation by gene profiling.
Sun X, Wei L, Lidén J, Hui G, Dahlman-Wright K, Hjerpe A, Dobra K
The Journal of pathology 2005 Sep;207(1):91-101
The Journal of pathology 2005 Sep;207(1):91-101
The duality of beta-catenin function: a requirement in lens morphogenesis and signaling suppression of lens fate in periocular ectoderm.
Smith AN, Miller LA, Song N, Taketo MM, Lang RA
Developmental biology 2005 Sep 15;285(2):477-89
Developmental biology 2005 Sep 15;285(2):477-89
Modulating the strength of cadherin adhesion: evidence for a novel adhesion complex.
Kim YJ, Sauer C, Testa K, Wahl JK, Svoboda RA, Johnson KR, Wheelock MJ, Knudsen KA
Journal of cell science 2005 Sep 1;118(Pt 17):3883-94
Journal of cell science 2005 Sep 1;118(Pt 17):3883-94
Disruption of Sertoli-germ cell adhesion function in the seminiferous epithelium of the rat testis can be limited to adherens junctions without affecting the blood-testis barrier integrity: an in vivo study using an androgen suppression model.
Xia W, Wong CH, Lee NP, Lee WM, Cheng CY
Journal of cellular physiology 2005 Oct;205(1):141-57
Journal of cellular physiology 2005 Oct;205(1):141-57
Gene expression in thyroid autonomous adenomas provides insight into their physiopathology.
Wattel S, Mircescu H, Venet D, Burniat A, Franc B, Frank S, Andry G, Van Sande J, Rocmans P, Dumont JE, Detours V, Maenhaut C
Oncogene 2005 Oct 20;24(46):6902-16
Oncogene 2005 Oct 20;24(46):6902-16
Connexin43 associated with an N-cadherin-containing multiprotein complex is required for gap junction formation in NIH3T3 cells.
Wei CJ, Francis R, Xu X, Lo CW
The Journal of biological chemistry 2005 May 20;280(20):19925-36
The Journal of biological chemistry 2005 May 20;280(20):19925-36
Simultaneous bilateral breast carcinoma: Histopathological characteristics and CD44/catenin-cadherin profile.
Bassarova AV, Torlakovic E, Sedloev T, Hristova SL, Trifonov DV, Nesland JM
Histology and histopathology 2005 Jul;20(3):791-9
Histology and histopathology 2005 Jul;20(3):791-9
Effect of N-cadherin misexpression by the mammary epithelium in mice.
Knudsen KA, Sauer C, Johnson KR, Wheelock MJ
Journal of cellular biochemistry 2005 Aug 15;95(6):1093-107
Journal of cellular biochemistry 2005 Aug 15;95(6):1093-107
P-cadherin overexpression is an indicator of clinical outcome in invasive breast carcinomas and is associated with CDH3 promoter hypomethylation.
Paredes J, Albergaria A, Oliveira JT, Jerónimo C, Milanezi F, Schmitt FC
Clinical cancer research : an official journal of the American Association for Cancer Research 2005 Aug 15;11(16):5869-77
Clinical cancer research : an official journal of the American Association for Cancer Research 2005 Aug 15;11(16):5869-77
Blood-testis barrier dynamics are regulated by {alpha}2-macroglobulin via the c-Jun N-terminal protein kinase pathway.
Wong CH, Mruk DD, Siu MK, Cheng CY
Endocrinology 2005 Apr;146(4):1893-908
Endocrinology 2005 Apr;146(4):1893-908
TGF-beta3 regulates anchoring junction dynamics in the seminiferous epithelium of the rat testis via the Ras/ERK signaling pathway: An in vivo study.
Xia W, Cheng CY
Developmental biology 2005 Apr 15;280(2):321-43
Developmental biology 2005 Apr 15;280(2):321-43
N-cadherin acts upstream of VE-cadherin in controlling vascular morphogenesis.
Luo Y, Radice GL
The Journal of cell biology 2005 Apr 11;169(1):29-34
The Journal of cell biology 2005 Apr 11;169(1):29-34
Breast cancer metastatic potential: correlation with increased heterotypic gap junctional intercellular communication between breast cancer cells and osteoblastic cells.
Kapoor P, Saunders MM, Li Z, Zhou Z, Sheaffer N, Kunze EL, Samant RS, Welch DR, Donahue HJ
International journal of cancer 2004 Sep 20;111(5):693-7
International journal of cancer 2004 Sep 20;111(5):693-7
Sertoli-Sertoli and Sertoli-germ cell interactions and their significance in germ cell movement in the seminiferous epithelium during spermatogenesis.
Mruk DD, Cheng CY
Endocrine reviews 2004 Oct;25(5):747-806
Endocrine reviews 2004 Oct;25(5):747-806
Zyxin, axin, and Wiskott-Aldrich syndrome protein are adaptors that link the cadherin/catenin protein complex to the cytoskeleton at adherens junctions in the seminiferous epithelium of the rat testis.
Lee NP, Mruk DD, Conway AM, Cheng CY
Journal of andrology 2004 Mar-Apr;25(2):200-15
Journal of andrology 2004 Mar-Apr;25(2):200-15
Immunohistochemical patterns for alpha- and beta-catenin, E- and N-cadherin expression in ovarian epithelial tumors.
Marques FR, Fonsechi-Carvasan GA, De Angelo Andrade LA, Böttcher-Luiz F
Gynecologic oncology 2004 Jul;94(1):16-24
Gynecologic oncology 2004 Jul;94(1):16-24
Interactions of proteases, protease inhibitors, and the beta1 integrin/laminin gamma3 protein complex in the regulation of ectoplasmic specialization dynamics in the rat testis.
Siu MK, Cheng CY
Biology of reproduction 2004 Apr;70(4):945-64
Biology of reproduction 2004 Apr;70(4):945-64
Pilomatrix carcinoma with lymph node metastases.
Bassarova A, Nesland JM, Sedloev T, Danielsen H, Christova S
Journal of cutaneous pathology 2004 Apr;31(4):330-5
Journal of cutaneous pathology 2004 Apr;31(4):330-5
Pilomatrix carcinoma with lymph node metastases.
Bassarova A, Nesland JM, Sedloev T, Danielsen H, Christova S
Journal of cutaneous pathology 2004 Apr;31(4):330-5
Journal of cutaneous pathology 2004 Apr;31(4):330-5
Oncoprotein profiles of primary peritoneal malignant mixed müllerian tumors.
Ng JS, Han AC, Edelson MI, Rosenblum NG
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 2003 Nov-Dec;13(6):870-4
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 2003 Nov-Dec;13(6):870-4
Oncoprotein profiles of primary peritoneal malignant mixed müllerian tumors.
Ng JS, Han AC, Edelson MI, Rosenblum NG
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 2003 Nov-Dec;13(6):870-4
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 2003 Nov-Dec;13(6):870-4
Alpha5beta1 integrin mediates strong tissue cohesion.
Robinson EE, Zazzali KM, Corbett SA, Foty RA
Journal of cell science 2003 Jan 15;116(Pt 2):377-86
Journal of cell science 2003 Jan 15;116(Pt 2):377-86
Is the cadherin/catenin complex a functional unit of cell-cell actin-based adherens junctions in the rat testis?
Lee NP, Mruk D, Lee WM, Cheng CY
Biology of reproduction 2003 Feb;68(2):489-508
Biology of reproduction 2003 Feb;68(2):489-508
Is the cadherin/catenin complex a functional unit of cell-cell actin-based adherens junctions in the rat testis?
Lee NP, Mruk D, Lee WM, Cheng CY
Biology of reproduction 2003 Feb;68(2):489-508
Biology of reproduction 2003 Feb;68(2):489-508
Value of E-cadherin and N-cadherin immunostaining in the diagnosis of mesothelioma.
Ordóñez NG
Human pathology 2003 Aug;34(8):749-55
Human pathology 2003 Aug;34(8):749-55
Value of E-cadherin and N-cadherin immunostaining in the diagnosis of mesothelioma.
Ordóñez NG
Human pathology 2003 Aug;34(8):749-55
Human pathology 2003 Aug;34(8):749-55
Cadherin-mediated adhesion is essential for myofibril continuity across the plasma membrane but not for assembly of the contractile apparatus.
Luo Y, Radice GL
Journal of cell science 2003 Apr 15;116(Pt 8):1471-9
Journal of cell science 2003 Apr 15;116(Pt 8):1471-9
Cadherin-mediated adhesion is essential for myofibril continuity across the plasma membrane but not for assembly of the contractile apparatus.
Luo Y, Radice GL
Journal of cell science 2003 Apr 15;116(Pt 8):1471-9
Journal of cell science 2003 Apr 15;116(Pt 8):1471-9
Mucoepidermoid carcinoma of the thyroid: a tumour histotype characterised by P-cadherin neoexpression and marked abnormalities of E-cadherin/catenins complex.
Rocha AS, Soares P, Machado JC, Máximo V, Fonseca E, Franssila K, Sobrinho-Simões M
Virchows Archiv : an international journal of pathology 2002 May;440(5):498-504
Virchows Archiv : an international journal of pathology 2002 May;440(5):498-504
P-cadherin expression is associated with high-grade ductal carcinoma in situ of the breast.
Paredes J, Milanezi F, Viegas L, Amendoeira I, Schmitt F
Virchows Archiv : an international journal of pathology 2002 Jan;440(1):16-21
Virchows Archiv : an international journal of pathology 2002 Jan;440(1):16-21
P-cadherin expression is associated with high-grade ductal carcinoma in situ of the breast.
Paredes J, Milanezi F, Viegas L, Amendoeira I, Schmitt F
Virchows Archiv : an international journal of pathology 2002 Jan;440(1):16-21
Virchows Archiv : an international journal of pathology 2002 Jan;440(1):16-21
Epithelial-type and neural-type cadherin expression in malignant noncarcinomatous neoplasms with epithelioid features that involve the soft tissues.
Laskin WB, Miettinen M
Archives of pathology & laboratory medicine 2002 Apr;126(4):425-31
Archives of pathology & laboratory medicine 2002 Apr;126(4):425-31
Remodeling the intercalated disc leads to cardiomyopathy in mice misexpressing cadherins in the heart.
Ferreira-Cornwell MC, Luo Y, Narula N, Lenox JM, Lieberman M, Radice GL
Journal of cell science 2002 Apr 15;115(Pt 8):1623-34
Journal of cell science 2002 Apr 15;115(Pt 8):1623-34
Remodeling the intercalated disc leads to cardiomyopathy in mice misexpressing cadherins in the heart.
Ferreira-Cornwell MC, Luo Y, Narula N, Lenox JM, Lieberman M, Radice GL
Journal of cell science 2002 Apr 15;115(Pt 8):1623-34
Journal of cell science 2002 Apr 15;115(Pt 8):1623-34
The Erbin PDZ domain binds with high affinity and specificity to the carboxyl termini of delta-catenin and ARVCF.
Laura RP, Witt AS, Held HA, Gerstner R, Deshayes K, Koehler MF, Kosik KS, Sidhu SS, Lasky LA
The Journal of biological chemistry 2002 Apr 12;277(15):12906-14
The Journal of biological chemistry 2002 Apr 12;277(15):12906-14
E-cadherin suppresses cellular transformation by inhibiting beta-catenin signaling in an adhesion-independent manner.
Gottardi CJ, Wong E, Gumbiner BM
The Journal of cell biology 2001 May 28;153(5):1049-60
The Journal of cell biology 2001 May 28;153(5):1049-60
E-cadherin suppresses cellular transformation by inhibiting beta-catenin signaling in an adhesion-independent manner.
Gottardi CJ, Wong E, Gumbiner BM
The Journal of cell biology 2001 May 28;153(5):1049-60
The Journal of cell biology 2001 May 28;153(5):1049-60
N-cadherin-mediated intercellular interactions promote survival and migration of melanoma cells.
Li G, Satyamoorthy K, Herlyn M
Cancer research 2001 May 1;61(9):3819-25
Cancer research 2001 May 1;61(9):3819-25
Cadherin junctions in mammary tumors.
Wheelock MJ, Soler AP, Knudsen KA
Journal of mammary gland biology and neoplasia 2001 Jul;6(3):275-85
Journal of mammary gland biology and neoplasia 2001 Jul;6(3):275-85
Cadherin junctions in mammary tumors.
Wheelock MJ, Soler AP, Knudsen KA
Journal of mammary gland biology and neoplasia 2001 Jul;6(3):275-85
Journal of mammary gland biology and neoplasia 2001 Jul;6(3):275-85
Abnormalities of the E-cadherin/catenin adhesion complex in classical papillary thyroid carcinoma and in its diffuse sclerosing variant.
Rocha AS, Soares P, Seruca R, Máximo V, Matias-Guiu X, Cameselle-Teijeiro J, Sobrinho-Simões M
The Journal of pathology 2001 Jul;194(3):358-66
The Journal of pathology 2001 Jul;194(3):358-66
Modulation of mouse neural crest cell motility by N-cadherin and connexin 43 gap junctions.
Xu X, Li WE, Huang GY, Meyer R, Chen T, Luo Y, Thomas MP, Radice GL, Lo CW
The Journal of cell biology 2001 Jul 9;154(1):217-30
The Journal of cell biology 2001 Jul 9;154(1):217-30
Rescuing the N-cadherin knockout by cardiac-specific expression of N- or E-cadherin.
Luo Y, Ferreira-Cornwell M, Baldwin H, Kostetskii I, Lenox J, Lieberman M, Radice G
Development (Cambridge, England) 2001 Feb;128(4):459-69
Development (Cambridge, England) 2001 Feb;128(4):459-69
Rescuing the N-cadherin knockout by cardiac-specific expression of N- or E-cadherin.
Luo Y, Ferreira-Cornwell M, Baldwin H, Kostetskii I, Lenox J, Lieberman M, Radice G
Development (Cambridge, England) 2001 Feb;128(4):459-69
Development (Cambridge, England) 2001 Feb;128(4):459-69
Dosage requirement and allelic expression of PAX6 during lens placode formation.
van Raamsdonk CD, Tilghman SM
Development (Cambridge, England) 2000 Dec;127(24):5439-48
Development (Cambridge, England) 2000 Dec;127(24):5439-48
The differential expression of N-cadherin and E-cadherin distinguishes pleural mesotheliomas from lung adenocarcinomas.
Peralta Soler A, Knudsen KA, Jaurand MC, Johnson KR, Wheelock MJ, Klein-Szanto AJ, Salazar H
Human pathology 1995 Dec;26(12):1363-9
Human pathology 1995 Dec;26(12):1363-9
The differential expression of N-cadherin and E-cadherin distinguishes pleural mesotheliomas from lung adenocarcinomas.
Peralta Soler A, Knudsen KA, Jaurand MC, Johnson KR, Wheelock MJ, Klein-Szanto AJ, Salazar H
Human pathology 1995 Dec;26(12):1363-9
Human pathology 1995 Dec;26(12):1363-9
No comments: Submit comment
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Western blot analysis of N-Cadherin was performed by loading 20 µg of Rat Brain (lane1), Mouse Brain (lane2) and C2C12 (lane3) lysates using Novex® NuPAGE® 4-12 % Bis-Tris gel (Product # NP0321BOX), XCell SureLock™ Electrophoresis System (Product # EI0002), Novex® Sharp Pre-Stained Protein Standard (LC5800). Proteins were transferred to a PVDF membrane and blocked with 5 % skim milk for 1 hour at room temperature. N-Cadherin was detected at ~130 kDa using N-Cadherin Mouse Monoclonal Antibody (Product # 33-3900) at 1 µg - 3 µg/mL in 2.5 % skim milk at 4°C overnight on a rocking platform. Goat Anti-Mouse IgG - HRP Secondary Antibody (Product # 62-6520) at 1:4000 dilution was used and chemiluminescent detection was performed using Pierce™ ECL Western Blotting Substrate (Product # 32106).
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Western blot analysis of total Cadherin and N-Cadherin was performed by loading 2 µL SeeBlue® Plus2 Prestained Protein Ladder (Product # LC5925), 50 µg of MDCK cell lysates and 10 µg mouse heart lysate per well onto a 4-20% Tris-HCl polyacrylamide gel. Proteins were transferred to a nitrocellulose membrane and blocked with 1% BSA/TBST for at least 1 hour at room temperature. Total cadherin was detected using a rabbit antibody (Product # 71-7100) and N-Cadherin was detected using a mouse antibody (Product # 33-3900), both at a concentration of 1 µg/mL in blocking buffer overnight at 4°C on a rocking platform. The blot was then incubated with goat anti-rabbit IgG-Alexa Fluor 790 secondary antibody (Product # A11369) and goat anti-mouse IgG-Alexa Fluor 680 secondary antibody (Product # A-21058) at a dilution of 1:10,000 for at least 1 hour. Fluorescent detection was performed using the Odyssey® CLx imaging system (Li-cor Biosciences). Image is generated by Joell Solan in Paul Lampe Lab at Fred Hutchinson Cancer Research Center.
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of N-Cadherin was done on 70% confluent log phase Caco-2 cells. The cells were fixed with 4% paraformaldehyde for 15 minutes; permeabilized with 0.25% Triton™ X-100 for 10 minutes followed by blocking with 5% BSA for 1 hour at room temperature. The cells were incubated with N-Cadherin Mouse Monoclonal Antibody (Product # 33-3900) at 1 µg - 2 µg in 1% BSA and incubated for 3 hours at room temperature and then labeled with Alexa Fluor® 488 Rabbit Anti-Mouse IgG Secondary Antibody (Product # A-11059) at a dilution of 1:400 for 30 minutes at room temperature (Panel a: green). Nuclei (Panel b: blue) were stained with SlowFade® Gold Antifade Mountant with DAPI (Product # S36938)and cytoskeletal F-actin (red) staining using Rhodamine Phalloidin (Product # R415, 1:300) panel c. Panel d is a merged image showing cell junctional localization of N-Cadherin. Panel e shows no primary antibody. The images were captured at 20X magnification.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of N-Cadherin was done on 70% confluent log phase Caco-2 cells. The cells were fixed with 4% paraformaldehyde for 15 minutes; permeabilized with 0.25% Triton™ X-100 for 10 minutes followed by blocking with 5% BSA for 1 hour at room temperature. The cells were incubated with N-Cadherin Mouse Monoclonal Antibody (Product # 33-3900) at 1 µg - 2 µg in 1% BSA and incubated for 3 hours at room temperature and then labeled with Alexa Fluor® 488 Rabbit Anti-Mouse IgG Secondary Antibody (Product # A-11059) at a dilution of 1:400 for 30 minutes at room temperature (Panel a: green). Nuclei (Panel b: blue) were stained with SlowFade® Gold Antifade Mountant with DAPI (Product # S36938). Panel c is a merged image showing cell junctional localization of N-Cadherin. Panel d shows no primary antibody. The images were captured at 20X magnification.
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Flow cytometry analysis of N-Cadherin was done on HeLa cells. Cells were fixed with 70% ethanol for 10 minutes, permeabilized with 0.25% Triton™ X-100 for 20 minutes, and blocked with 5% BSA for 1 hour at room temperature. Cells were labeled with N-Cadherin Mouse Monoclonal Antibody (333900, red histogram) or with mouse isotype control (pink histogram) at 2 µg - 4 µg/million cells in 2.5% BSA. After incubation at room temperature for 2 - 3 hours, the cells were labeled with Alexa Fluor® 488 Rabbit Anti-Mouse Secondary Antibody (A11059) at a dilution of 1:400 for 30 minutes at room temperature. The representative 10,000 cells were acquired and analyzed for each sample using an Attune® Acoustic Focusing Cytometer. The purple histogram represents unstained control cells and the green histogram represents no-primary-antibody control.
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- NULL
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- NULL
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- NULL
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- NULL
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- NULL
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- NULL
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- NULL
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- NULL
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- NULL
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- NULL
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- NULL
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- NULL
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- NULL
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Figure 3 Re-morphogenesis of ARPE-19 cells treated with ITS. (A) The photomicrographs show ARPE-19 cells cultured for 4 weeks with ITS and stained for actin with Texas Red-X phalloidin. Note the tight intercellular contact, epithelial-like cellular shape, and predominantly peripheral cortical actin staining. Confocal immunofluorescence images of the same culture conditions showing beta-catenin (B) and N-cadherin (C) at the lateral membrane, CD147 (D) mostly in the apical domain and ezrin (E) in the apical domain. (F) The immunofluorescence image shows immunostaining of the alpha 1 subunit of Na + , K + -ATPase at the lateral membrane and more precisely, as observed in the XZ image, at the cell-cell contacts. (G) The beta 1 subunit is observed at the cell border and at the apical domain; the XZ image confirms both basolateral and apical staining. (H) The beta 2 subunit is observed mainly at the apical domain; the XZ image confirms apical staining. Scale bar: 10 mum. (I) Quantitative analysis of the transepithelial resistance (TER) of ARPE-19 cells during re-morphogenesis is depicted. Note a stable TER of ~80 Omega cm 2 between the second and fourth week in culture.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Figure 3 Rai14 is an apical and basal ES protein in the rat testis. Dual-labeled immunofluorescence analysis was used to assess co-localization of Rai14 (red) with constituent protein laminin-gamma3 chain (green), actin regulatory protein Arp3 (green), actin binding protein drebrin E (green) and actin filament cross-linking protein palladin (green) at the apical ES in stage VII tubules when these proteins were all highly expressed. It was found that Rai14 indeed partially co-localized with each of these apical ES proteins (see ""orange yellow"" in merged images) as shown in ( A ). Rai14 (red) also partially co-localized with basal ES/TJ protein ZO-1 (see ""yellow"" arrowheads), and to a lesser extent with N-cadherin (see ""white"" arrowheads) in stage IV-V tubules when these proteins were highly expressed as shown in ( B ). Bar = 10 um in ( A ) or ( B ), which applies all other images in ( A ) and ( B ).
