844703

antibody from BioLegend

Targeting: CDH2 CD325, CDHN, NCAD

Immunocytochemistry

Immunoprecipitation

Immunohistochemistry

Antibody data

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Validation data

Product number: 844703 - Provider product page
Provider: BioLegend
Proper citation: BioLegend Cat#844703, RRID:AB_2565807
Product name: Ultra-LEAF™ Purified anti-CD325 (N-Cadherin)
Antibody type: Monoclonal
Antigen: Human N-cadherin cytoplasmic domain fused to recombinant MBP.
Description: CD325 (N-cadherin) is important for neuronal migration during development, neurite outgrowth and target finding during differentiation, initial formation of synapses, and synaptic plasticity in mature neurons. CD325 (N-cadherin) is a 130 kD single pass transmembrane protein. Its extracellular region consists of five extracellular cadherin domains and has one cytoplasmic domain. N-cadherin is involved in organogenesis and in the maintenance of organ architecture by contributing to the sorting of heterogeneous cell types and in the cell adhesion needed to form tissues. N-cadherin is expressed by stem cells, myeloblasts, endothelial cells, fibroblasts, and also is expressed in neural and muscle tissues along with some types of carcinoma cells. CD325 associates with the cytoskeleton trough catenin proteins.
Reactivity: Human, Mouse, Rat
Host: Mouse
Conjugate: Unconjugated
Antibody clone number: 13A9
Vial size: 100 µg
Concentration: 1.0 mg/ml
Storage: 2°C-8°C
Handling: Ambient RT

CDH2 protein structure - 844703 shown in red.