Antibody data
- Antibody Data
- Antigen structure
- References [24]
- Comments [0]
- Validations
- Flow cytometry [1]
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- Product number
- A01577-3 - Provider product page
- Provider
- Boster Biological Technology
- Product name
- Anti-N Cadherin/CDH2 Antibody Picoband™
- Antibody type
- Polyclonal
- Description
- Rabbit IgG polyclonal antibody for N Cadherin/CDH2 detection. Tested with WB, IHC-P, FCM, Direct ELISA in Human;Mouse;Rat.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Vial size
- 100μg/vial
- Concentration
- Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
- Storage
- At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
- Handling
- Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Submitted references Expression and potential molecular mechanism of TOP2A in metastasis of non-small cell lung cancer.
PD-L1 knockdown suppresses vasculogenic mimicry of non-small cell lung cancer by modulating ZEB1-triggered EMT.
SNHG15-Mediated Localization of Nucleolin at the Cell Protrusions Regulates CDH2 mRNA Expression and Cell Invasion.
Hepatocyte-targeted delivery using oleanolic acid-loaded liposomes for enhanced hepatocellular carcinoma therapy.
Microtubule-associated protein 4 promotes epithelial mesenchymal transition in hepatocellular cancer cells via regulating GSK3β/β-catenin pathway.
DLGAP4 acts as an effective prognostic predictor for hepatocellular carcinoma and is closely related to tumour progression.
Nuciferine Inhibits TMEM16A in Dietary Adjuvant Therapy for Lung Cancer.
Caffeic Acid, an Active Ingredient in Coffee, Combines with DOX for Multitarget Combination Therapy of Lung Cancer.
Inhibition of TMEM16A by Natural Product Silibinin: Potential Lead Compounds for Treatment of Lung Adenocarcinoma.
TMEM16A, a Homoharringtonine Receptor, as a Potential Endogenic Target for Lung Cancer Treatment.
RETRACTED: BMSCs-derived exosomal microRNA-let-7a plays a protective role in diabetic nephropathy via inhibition of USP22 expression.
Sohlh2 alleviates malignancy of EOC cells under hypoxia via inhibiting the HIF1α/CA9 signaling pathway.
MDM2 promotes epithelial-mesenchymal transition through activation of Smad2/3 signaling pathway in lung adenocarcinoma.
Identification and differentiation therapy strategy of pterygium in vitro.
The CXCL12-CXCR4 axis promotes migration, invasiveness, and EMT in human papillary thyroid carcinoma B-CPAP cells via NF-κB signaling.
Andrographolide Induces Autophagic Cell Death and Inhibits Invasion and Metastasis of Human Osteosarcoma Cells in An Autophagy-Dependent Manner.
Kallikrein-related peptidase 4 contributes to the tumor metastasis of oral squamous cell carcinoma.
Tetrahydrocurcumin induces mesenchymal-epithelial transition and suppresses angiogenesis by targeting HIF-1α and autophagy in human osteosarcoma.
RAC1 overexpression promotes the proliferation, migration and epithelial-mesenchymal transition of lens epithelial cells.
Wnt/β-catenin pathway is required for epithelial to mesenchymal transition in CXCL12 over expressed breast cancer cells.
MiR-506 inhibits multiple targets in the epithelial-to-mesenchymal transition network and is associated with good prognosis in epithelial ovarian cancer.
Expression of N-cadherin in myocardial tissues during the development of a rat heart.
Expression of N-cadherin proteins in myocardial hypertrophy in rats.
Overexpression of SOX2 promotes migration, invasion, and epithelial-mesenchymal transition through the Wnt/β-catenin pathway in laryngeal cancer Hep-2 cells.
Wu J, Li W, Zhang X, Shi F, Jia Q, Wang Y, Shi Y, Wu S, Wang X
Scientific reports 2024 May 28;14(1):12228
Scientific reports 2024 May 28;14(1):12228
PD-L1 knockdown suppresses vasculogenic mimicry of non-small cell lung cancer by modulating ZEB1-triggered EMT.
Li W, Wu J, Jia Q, Shi Y, Li F, Zhang L, Shi F, Wang X, Wu S
BMC cancer 2024 May 23;24(1):633
BMC cancer 2024 May 23;24(1):633
SNHG15-Mediated Localization of Nucleolin at the Cell Protrusions Regulates CDH2 mRNA Expression and Cell Invasion.
Chen S, Zhou Y, Peng P, Xu L, Tang Q, Chen W, Gu W
International journal of molecular sciences 2023 Oct 26;24(21)
International journal of molecular sciences 2023 Oct 26;24(21)
Hepatocyte-targeted delivery using oleanolic acid-loaded liposomes for enhanced hepatocellular carcinoma therapy.
Wei X, Yang D, Xing Z, Cai J, Wang L, Zhao C, Wei X, Jiang M, Sun H, Zhou L, Fan Y, Nie H, Liu H
Biomaterials science 2023 May 30;11(11):3952-3964
Biomaterials science 2023 May 30;11(11):3952-3964
Microtubule-associated protein 4 promotes epithelial mesenchymal transition in hepatocellular cancer cells via regulating GSK3β/β-catenin pathway.
Hu P, Zong B, Chen Q, Shao R, Chen M, Yang Y, Shao G
Heliyon 2023 Mar;9(3):e14309
Heliyon 2023 Mar;9(3):e14309
DLGAP4 acts as an effective prognostic predictor for hepatocellular carcinoma and is closely related to tumour progression.
Dong C, Huang S, Sun L, Yao J, Yan J, Yin X
Scientific reports 2022 Nov 17;12(1):19775
Scientific reports 2022 Nov 17;12(1):19775
Nuciferine Inhibits TMEM16A in Dietary Adjuvant Therapy for Lung Cancer.
Bai X, Liu X, Li S, An H, Kang X, Guo S
Journal of agricultural and food chemistry 2022 Mar 30;70(12):3687-3696
Journal of agricultural and food chemistry 2022 Mar 30;70(12):3687-3696
Caffeic Acid, an Active Ingredient in Coffee, Combines with DOX for Multitarget Combination Therapy of Lung Cancer.
Bai X, Li S, Liu X, An H, Kang X, Guo S
Journal of agricultural and food chemistry 2022 Jul 13;70(27):8326-8337
Journal of agricultural and food chemistry 2022 Jul 13;70(27):8326-8337
Inhibition of TMEM16A by Natural Product Silibinin: Potential Lead Compounds for Treatment of Lung Adenocarcinoma.
Guo S, Bai X, Liu Y, Shi S, Wang X, Zhan Y, Kang X, Chen Y, An H
Frontiers in pharmacology 2021;12:643489
Frontiers in pharmacology 2021;12:643489
TMEM16A, a Homoharringtonine Receptor, as a Potential Endogenic Target for Lung Cancer Treatment.
Guo S, Bai X, Shi S, Deng Y, Kang X, An H
International journal of molecular sciences 2021 Oct 10;22(20)
International journal of molecular sciences 2021 Oct 10;22(20)
RETRACTED: BMSCs-derived exosomal microRNA-let-7a plays a protective role in diabetic nephropathy via inhibition of USP22 expression.
Mao R, Shen J, Hu X
Life sciences 2021 Mar 1;268:118937
Life sciences 2021 Mar 1;268:118937
Sohlh2 alleviates malignancy of EOC cells under hypoxia via inhibiting the HIF1α/CA9 signaling pathway.
Zhang X, Liu X, Cui W, Zhang R, Liu Y, Li Y, Hao J
Biological chemistry 2020 Feb 25;401(2):263-271
Biological chemistry 2020 Feb 25;401(2):263-271
MDM2 promotes epithelial-mesenchymal transition through activation of Smad2/3 signaling pathway in lung adenocarcinoma.
Tang Y, Xuan Y, Qiao G, Ou Z, He Z, Zhu Q, Liao M, Yin G
OncoTargets and therapy 2019;12:2247-2258
OncoTargets and therapy 2019;12:2247-2258
Identification and differentiation therapy strategy of pterygium in vitro.
Hu X, Tandra N, Zhang Z, Gong A, Chen J, Li Y, Chen Q, Xu W, Qian H
American journal of translational research 2018;10(8):2619-2627
American journal of translational research 2018;10(8):2619-2627
The CXCL12-CXCR4 axis promotes migration, invasiveness, and EMT in human papillary thyroid carcinoma B-CPAP cells via NF-κB signaling.
Lin Y, Ma Q, Li L, Wang H
Biochemistry and cell biology = Biochimie et biologie cellulaire 2018 Oct;96(5):619-626
Biochemistry and cell biology = Biochimie et biologie cellulaire 2018 Oct;96(5):619-626
Andrographolide Induces Autophagic Cell Death and Inhibits Invasion and Metastasis of Human Osteosarcoma Cells in An Autophagy-Dependent Manner.
Liu Y, Zhang Y, Zou J, Yan L, Yu X, Lu P, Wu X, Li Q, Gu R, Zhu D
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;44(4):1396-1410
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;44(4):1396-1410
Kallikrein-related peptidase 4 contributes to the tumor metastasis of oral squamous cell carcinoma.
Cui Z, Cui Y, Luo G, Yang S, Ling X, Lou Y, Sun X
Bioscience, biotechnology, and biochemistry 2017 Sep;81(9):1768-1777
Bioscience, biotechnology, and biochemistry 2017 Sep;81(9):1768-1777
Tetrahydrocurcumin induces mesenchymal-epithelial transition and suppresses angiogenesis by targeting HIF-1α and autophagy in human osteosarcoma.
Zhang Y, Liu Y, Zou J, Yan L, Du W, Zhang Y, Sun H, Lu P, Geng S, Gu R, Zhang H, Bi Z
Oncotarget 2017 Oct 31;8(53):91134-91149
Oncotarget 2017 Oct 31;8(53):91134-91149
RAC1 overexpression promotes the proliferation, migration and epithelial-mesenchymal transition of lens epithelial cells.
Su J, Li H
International journal of clinical and experimental pathology 2015;8(9):10760-7
International journal of clinical and experimental pathology 2015;8(9):10760-7
Wnt/β-catenin pathway is required for epithelial to mesenchymal transition in CXCL12 over expressed breast cancer cells.
Shan S, Lv Q, Zhao Y, Liu C, Sun Y, Xi K, Xiao J, Li C
International journal of clinical and experimental pathology 2015;8(10):12357-67
International journal of clinical and experimental pathology 2015;8(10):12357-67
MiR-506 inhibits multiple targets in the epithelial-to-mesenchymal transition network and is associated with good prognosis in epithelial ovarian cancer.
Sun Y, Hu L, Zheng H, Bagnoli M, Guo Y, Rupaimoole R, Rodriguez-Aguayo C, Lopez-Berestein G, Ji P, Chen K, Sood AK, Mezzanzanica D, Liu J, Sun B, Zhang W
The Journal of pathology 2015 Jan;235(1):25-36
The Journal of pathology 2015 Jan;235(1):25-36
Expression of N-cadherin in myocardial tissues during the development of a rat heart.
Mu LM, Wang WF, Zheng H, Guo ZK, Zhang GM
Genetics and molecular research : GMR 2015 Aug 19;14(3):9882-9
Genetics and molecular research : GMR 2015 Aug 19;14(3):9882-9
Expression of N-cadherin proteins in myocardial hypertrophy in rats.
Mu L, Jing C, Guo Z
Experimental and therapeutic medicine 2014 Feb;7(2):355-359
Experimental and therapeutic medicine 2014 Feb;7(2):355-359
Overexpression of SOX2 promotes migration, invasion, and epithelial-mesenchymal transition through the Wnt/β-catenin pathway in laryngeal cancer Hep-2 cells.
Yang N, Hui L, Wang Y, Yang H, Jiang X
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2014 Aug;35(8):7965-73
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2014 Aug;35(8):7965-73
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Supportive validation
- Submitted by
- Boster Biological Technology (provider)
- Main image
- Experimental details
- Flow Cytometry analysis of HEPG2 cells using anti-N Cadherin/CDH2 antibody (A01577-3). Overlay histogram showing HEPG2 cells stained with A01577-3 (Blue line).The cells were blocked with 10% normal goat serum. And then incubated with rabbit anti-N Cadherin/CDH2 Antibody (A01577-3, 1μg/1x106 cells) for 30 min at 20°C. DyLight®488 conjugated goat anti-rabbit IgG (BA1127, 5-10μg/1x106 cells) was used as secondary antibody for 30 minutes at 20°C. Isotype control antibody (Green line) was rabbit IgG (1μg/1x106) used under the same conditions. Unlabelled sample (Red line) was also used as a control.
- Additional image