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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
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- Validations
- Flow cytometry [1]
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- Product number
- 350810 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#350810, RRID:AB_11219390
- Product name
- Alexa Fluor® 488 anti-human CD325 (N-Cadherin) [8C11]
- Antibody type
- Monoclonal
- Antigen
- Recombinant human N-cadherin extracellular domain
- Description
- CD325 (N-cadherin) is a 130 kD, single pass transmembrane protein. Its extracellular region consists of five EC domains and has one cytoplasmic domain. N-cadherin is involved in organogenesis and maintenance of organ architecture by contributing to the sorting of heterogeneous cell types and in the cell adhesion needed to form tissues. N-cadherin is expressed by stem cells, myeloblasts, endothelial cells, and fibroblasts, and also is expressed in neural and muscle tissues and some types of carcinoma cells. CD325 associates with the cytoskeleton trough catenin proteins.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Green dye
- Isotype
- IgG
- Vial size
- 100 tests
- Storage
- The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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Supportive validation
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- BioLegend (provider)
- Main image
- Experimental details
- Human acute myeloid leukemia cell line (KG1a) was stained with CD325 (clone 8C11) Alexa Fluor® 488 (filled histogram) or mouse IgG1a, κ Alexa Fluor® 488 (open histogram).
- Conjugate
- Green dye
