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- References [92]
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- Product number
- 10084-2-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10084-2-AP, RRID:AB_2240403
- Product name
- CD71 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated CD71 antibody (Cat. #10084-2-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Propofol and Dexmedetomidine Ameliorate Endotoxemia-Associated Encephalopathy via Inhibiting Ferroptosis.
Injectable, anti-collapse, adhesive, plastic and bioactive bone graft substitute promotes bone regeneration by moderating oxidative stress in osteoporotic bone defect.
Kinase PIM1 governs ferroptosis to reduce retinal microvascular endothelial cell dysfunction triggered by high glucose.
Glioma-targeted oxaliplatin/ferritin clathrate reversing the immunosuppressive microenvironment through hijacking Fe(2+) and boosting Fenton reaction.
Nicorandil Regulates Ferroptosis and Mitigates Septic Cardiomyopathy via TLR4/SLC7A11 Signaling Pathway.
Salvia miltiorrhiza Bge. processed with porcine cardiac blood inhibited GLRX5-mediated ferroptosis alleviating cerebral ischemia-reperfusion injury.
Ambra1 in exosomes secreted by HK-2 cells damaged by supersaturated oxalate induce mitophagy and autophagy-ferroptosis in normal HK-2 cells to participate in the occurrence of kidney stones.
Transient receptor potential channel TRPM4 favors oxidized low-density lipoprotein-induced coronary endothelial cell dysfunction via a mechanism involving ferroptosis.
Heterogeneous ferroptosis susceptibility of macrophages caused by focal iron overload exacerbates rheumatoid arthritis.
The clustering status of detached gastric cancer cells inhibits anoikis-induced ferroptosis to promote metastatic colonization.
Pro-ferroptotic signaling promotes arterial aging via vascular smooth muscle cell senescence.
Bulk RNA-sequencing, single-cell RNA-sequencing analysis, and experimental validation reveal iron metabolism-related genes CISD2 and CYP17A1 are potential diagnostic markers for recurrent pregnancy loss.
Targeted delivery of MerTK protein via cell membrane engineered nanoparticle enhances efferocytosis and attenuates atherosclerosis in diabetic ApoE(-/-) Mice.
Targeted elimination of senescent cells by engineered extracellular vesicles attenuates atherosclerosis in ApoE(-/-) mice with minimal side effects.
Overexpressed transferrin receptor implied poor prognosis and relapse in gastrointestinal stromal tumors.
Bioengineered "Molecular Glue"-Mediated Tumor-Specific Cascade Nanoreactors with Self-Destruction Ability for Enhanced Precise Starvation/Chemosynergistic Tumor Therapy.
Knockdown of ANXA10 induces ferroptosis by inhibiting autophagy-mediated TFRC degradation in colorectal cancer.
Yttrium chloride induces ferroptosis in cardiomyocytes via iron accumulation and triggers cardiac lipid peroxidation and inflammation that cause heart adverse events in mice.
Activation of Nrf2 signalling pathway by tectoridin protects against ferroptosis in particulate matter-induced lung injury.
Exogenous H(2)S initiating Nrf2/GPx4/GSH pathway through promoting Syvn1-Keap1 interaction in diabetic hearts.
Curcumin alleviates AFB1-induced nephrotoxicity in ducks: regulating mitochondrial oxidative stress, ferritinophagy, and ferroptosis.
Hydrogen sulfide ameliorates endothelial dysfunction in aging arteries by regulating ferroptosis.
Loureirin C inhibits ferroptosis after cerebral ischemia reperfusion through regulation of the Nrf2 pathway in mice.
Artesunate, a new antimalarial clinical drug, exhibits potent anti-AML activity by targeting the ROS/Bim and TFRC/Fe(2+) pathways.
Dihydroartemisinin-induced ferroptosis in acute myeloid leukemia: links to iron metabolism and metallothionein.
Thorium(IV) triggers ferroptosis through disrupting iron homeostasis and heme metabolism in the liver following oral ingestion.
Palmitic acid-induced ferroptosis via CD36 activates ER stress to break calcium-iron balance in colon cancer cells.
ATM orchestrates ferritinophagy and ferroptosis by phosphorylating NCOA4.
Hydrogen sulfide alleviates mitochondrial damage and ferroptosis by regulating OPA3-NFS1 axis in doxorubicin-induced cardiotoxicity.
Fucoxanthin triggers ferroptosis in glioblastoma cells by stabilizing the transferrin receptor.
Melatonin inhibits ferroptosis and delays age-related cataract by regulating SIRT6/p-Nrf2/GPX4 and SIRT6/NCOA4/FTH1 pathways.
Sphingosine 1-phosphate alleviates radiation-induced ferroptosis in ovarian granulosa cells by upregulating glutathione peroxidase 4.
ATP6V0D1 promotes alkaliptosis by blocking STAT3-mediated lysosomal pH homeostasis.
Ferroptotic stress facilitates smooth muscle cell dedifferentiation in arterial remodelling by disrupting mitochondrial homeostasis.
Ferroptosis is involved in PM2.5-induced acute nasal epithelial injury via AMPK-mediated autophagy.
Ferroptosis is involved in corpus cavernosum smooth muscle cells impairment in diabetes mellitus-induced erectile dysfunction.
Transferrin Receptor is Associated with Sensitivity to Ferroptosis Inducers in Hepatocellular Carcinoma.
Knockdown of SETD2 promotes erastin-induced ferroptosis in ccRCC.
Hormone replacement therapy for postmenopausal atherosclerosis is offset by late age iron deposition.
LncRNA modulates Hippo-YAP signaling to reprogram iron metabolism.
EPC-exosomal miR-26a-5p improves airway remodeling in COPD by inhibiting ferroptosis of bronchial epithelial cells via PTGS2/PGE2 signaling pathway.
Cyclosporine A-loaded apoferritin alleviates myocardial ischemia-reperfusion injury by simultaneously blocking ferroptosis and apoptosis of cardiomyocytes.
Single-cell transcriptomics uncover the key ferroptosis regulators contribute to cancer progression in head and neck squamous cell carcinoma.
Role of TFRC as a Novel Prognostic Biomarker and in Immunotherapy for Pancreatic Carcinoma.
Exosomes derived from pericardial adipose tissues attenuate cardiac remodeling following myocardial infarction by Adipsin-regulated iron homeostasis.
Hepatic TGFβr1 Deficiency Attenuates Lipopolysaccharide/D-Galactosamine-Induced Acute Liver Failure Through Inhibiting GSK3β-Nrf2-Mediated Hepatocyte Apoptosis and Ferroptosis.
Dexmedetomidine prevents hemorrhagic brain injury by reducing damage induced by ferroptosis in mice.
Phospholipid peroxidation-driven modification of chondrogenic transcription factor mediates alkoxyl radicals-induced impairment of embryonic bone development.
L-Citrulline Supplementation Restrains Ferritinophagy-Mediated Ferroptosis to Alleviate Iron Overload-Induced Thymus Oxidative Damage and Immune Dysfunction.
Per1/Per2 knockout Affects Spleen Immune Function in Elderly Mice via Inducing Spleen Lymphocyte Ferroptosis.
Farrerol alleviates collagenase-induced tendinopathy by inhibiting ferroptosis in rats.
Spatial region-resolved proteome map reveals mechanism of COVID-19-associated heart injury.
ENO1 suppresses cancer cell ferroptosis by degrading the mRNA of iron regulatory protein 1.
3D two-photon brain imaging reveals dihydroartemisinin exerts antiepileptic effects by modulating iron homeostasis.
Lipid kinases VPS34 and PIKfyve coordinate a phosphoinositide cascade to regulate retriever-mediated recycling on endosomes.
Aging is associated with increased brain iron through cortex-derived hepcidin expression.
Iron transport across the human placenta is regulated by hepcidin.
Leonurine alleviates ferroptosis in cisplatin-induced acute kidney injury by activating the Nrf2 signalling pathway.
The role of ferritin and iron dextran in exacerbating preeclampsia in an L-NAME-treated rat model.
The Ferroptosis-NLRP1 Inflammasome: The Vicious Cycle of an Adverse Pregnancy.
WDR45 Mutation Impairs the Autophagic Degradation of Transferrin Receptor and Promotes Ferroptosis.
Ferroportin-Dependent Iron Homeostasis Protects against Oxidative Stress-Induced Nucleus Pulposus Cell Ferroptosis and Ameliorates Intervertebral Disc Degeneration In Vivo.
Oxalate Activates Autophagy to Induce Ferroptosis of Renal Tubular Epithelial Cells and Participates in the Formation of Kidney Stones.
The blood-brain barrier studied in vitro across species.
Dipetidyl peptidase-4 and transferrin receptor serve as prognostic biomarkers for acute myeloid leukemia.
The metabolite α-KG induces GSDMC-dependent pyroptosis through death receptor 6-activated caspase-8.
Chitosan-based nanoparticle co-delivery of docetaxel and curcumin ameliorates anti-tumor chemoimmunotherapy in lung cancer.
Atractylodin may induce ferroptosis of human hepatocellular carcinoma cells.
Seizure-mediated iron accumulation and dysregulated iron metabolism after status epilepticus and in temporal lobe epilepsy.
LPS-induced macrophage HMGB1-loaded extracellular vesicles trigger hepatocyte pyroptosis by activating the NLRP3 inflammasome.
Nuciferine protects against folic acid-induced acute kidney injury by inhibiting ferroptosis.
Tolerable upper intake level of iron damages the liver of weaned piglets.
Tetrachlorobenzoquinone exposure triggers ferroptosis contributing to its neurotoxicity.
LncRNA RP1-86C11.7 exacerbates the glioma progression and oncogenicity by hsa-miR-144-3p/TFRC signaling.
A novel signature constructed by ferroptosis-associated genes (FAGs) for the prediction of prognosis in bladder urothelial carcinoma (BLCA) and associated with immune infiltration.
Fostered Nrf2 expression antagonizes iron overload and glutathione depletion to promote resistance of neuron-like cells to ferroptosis.
Transferrin receptor 1 targeted optical imaging for identifying glioma margin in mouse models.
miR-30-5p-mediated ferroptosis of trophoblasts is implicated in the pathogenesis of preeclampsia.
A novel iron(II) phenanthroline complex exhibits anticancer activity against TFR1-overexpressing esophageal squamous cell carcinoma cells through ROS accumulation and DNA damage.
Mutant huntingtin induces iron overload via up-regulating IRP1 in Huntington's disease.
Retention of Mitochondria in Mature Human Red Blood Cells as the Result of Autophagy Impairment in Rett Syndrome.
FBW7 increases the chemosensitivity of pancreatic cancer cells to gemcitabine through upregulation of ENT1.
Long-Term Dexamethasone Exposure Down-Regulates Hepatic TFR1 and Reduces Liver Iron Concentration in Rats.
Myricetin ameliorates scopolamine-induced memory impairment in mice via inhibiting acetylcholinesterase and down-regulating brain iron.
Maternal protein restriction depresses the duodenal expression of iron transporters and serum iron level in male weaning piglets.
Intracellular Released Payload Influences Potency and Bystander-Killing Effects of Antibody-Drug Conjugates in Preclinical Models.
Liver metal levels and expression of genes related to iron homeostasis in rhesus monkeys after inhalational manganese exposure.
Iron homeostasis and its disruption in mouse lung in iron deficiency and overload.
Dysregulated iron metabolism in the choroid plexus in fragile X-associated tremor/ataxia syndrome.
Mono-ubiquitylated ORF45 Mediates Association of KSHV Particles with Internal Lipid Rafts for Viral Assembly and Egress.
Adaptor protein complex 2-mediated, clathrin-dependent endocytosis, and related gene activities, are a prominent feature during maturation stage amelogenesis.
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Zhou Y, Yang Y, Yi L, Pan M, Tang W, Duan H
Drug design, development and therapy 2024;18:1349-1368
Drug design, development and therapy 2024;18:1349-1368
Injectable, anti-collapse, adhesive, plastic and bioactive bone graft substitute promotes bone regeneration by moderating oxidative stress in osteoporotic bone defect.
Huang L, Zhang S, Bian M, Xiang X, Xiao L, Wang J, Lu S, Chen W, Zhang C, Mo G, Jiang L, Li Y, Zhang J
Acta biomaterialia 2024 May;180:82-103
Acta biomaterialia 2024 May;180:82-103
Kinase PIM1 governs ferroptosis to reduce retinal microvascular endothelial cell dysfunction triggered by high glucose.
Xie HB, Guo JH, Yang MM, Wang JT
In vitro cellular & developmental biology. Animal 2024 Mar;60(3):278-286
In vitro cellular & developmental biology. Animal 2024 Mar;60(3):278-286
Glioma-targeted oxaliplatin/ferritin clathrate reversing the immunosuppressive microenvironment through hijacking Fe(2+) and boosting Fenton reaction.
Li X, Cheng Y, Yang Z, Ji Q, Huan M, Ye W, Liu M, Zhang B, Liu D, Zhou S
Journal of nanobiotechnology 2024 Mar 5;22(1):93
Journal of nanobiotechnology 2024 Mar 5;22(1):93
Nicorandil Regulates Ferroptosis and Mitigates Septic Cardiomyopathy via TLR4/SLC7A11 Signaling Pathway.
Lu JS, Wang JH, Han K, Li N
Inflammation 2024 Jun;47(3):975-988
Inflammation 2024 Jun;47(3):975-988
Salvia miltiorrhiza Bge. processed with porcine cardiac blood inhibited GLRX5-mediated ferroptosis alleviating cerebral ischemia-reperfusion injury.
Zhou S, Wang Z, Wang T, Peng C, Zhang J, Liu C, Xu J, Zhang Y, Zhang L, Luo L, Yan X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155622
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155622
Ambra1 in exosomes secreted by HK-2 cells damaged by supersaturated oxalate induce mitophagy and autophagy-ferroptosis in normal HK-2 cells to participate in the occurrence of kidney stones.
Su X, Song C, He Z, Song Q, Meng L, Dong C, Zhou J, Ke H, Xiong Y, Liu J, Liao W, Yang S
Biochimica et biophysica acta. Molecular cell research 2024 Jan;1871(1):119604
Biochimica et biophysica acta. Molecular cell research 2024 Jan;1871(1):119604
Transient receptor potential channel TRPM4 favors oxidized low-density lipoprotein-induced coronary endothelial cell dysfunction via a mechanism involving ferroptosis.
Ye F, Liu D, Zhang J
Tissue & cell 2024 Feb;86:102290
Tissue & cell 2024 Feb;86:102290
Heterogeneous ferroptosis susceptibility of macrophages caused by focal iron overload exacerbates rheumatoid arthritis.
Liu Y, Luo X, Chen Y, Dang J, Zeng D, Guo X, Weng W, Zhao J, Shi X, Chen J, Dong B, Zhong S, Ren J, Li Y, Wang J, Zhang J, Sun J, Xu H, Lu Y, Brand D, Zheng SG, Pan Y
Redox biology 2024 Feb;69:103008
Redox biology 2024 Feb;69:103008
The clustering status of detached gastric cancer cells inhibits anoikis-induced ferroptosis to promote metastatic colonization.
Sun J, Li J, Pantopoulos K, Liu Y, He Y, Kang W, Ye X
Cancer cell international 2024 Feb 18;24(1):77
Cancer cell international 2024 Feb 18;24(1):77
Pro-ferroptotic signaling promotes arterial aging via vascular smooth muscle cell senescence.
Sun DY, Wu WB, Wu JJ, Shi Y, Xu JJ, Ouyang SX, Chi C, Shi Y, Ji QX, Miao JH, Fu JT, Tong J, Zhang PP, Zhang JB, Li ZY, Qu LF, Shen FM, Li DJ, Wang P
Nature communications 2024 Feb 16;15(1):1429
Nature communications 2024 Feb 16;15(1):1429
Bulk RNA-sequencing, single-cell RNA-sequencing analysis, and experimental validation reveal iron metabolism-related genes CISD2 and CYP17A1 are potential diagnostic markers for recurrent pregnancy loss.
He YB, Han L, Wang C, Fang J, Shang Y, Cai HL, Zhou Q, Zhang ZZ, Chen SL, Li JY, Liu YL
Gene 2024 Apr 5;901:148168
Gene 2024 Apr 5;901:148168
Targeted delivery of MerTK protein via cell membrane engineered nanoparticle enhances efferocytosis and attenuates atherosclerosis in diabetic ApoE(-/-) Mice.
Qiu S, Liu J, Chen J, Li Y, Bu T, Li Z, Zhang L, Sun W, Zhou T, Hu W, Yang G, Yuan L, Duan Y, Xing C
Journal of nanobiotechnology 2024 Apr 13;22(1):178
Journal of nanobiotechnology 2024 Apr 13;22(1):178
Targeted elimination of senescent cells by engineered extracellular vesicles attenuates atherosclerosis in ApoE(-/-) mice with minimal side effects.
Zhang L, Wang C, Hu W, Bu T, Sun W, Zhou T, Qiu S, Wei M, Xing H, Li Z, Yang G, Yuan L
Theranostics 2023;13(14):5114-5129
Theranostics 2023;13(14):5114-5129
Overexpressed transferrin receptor implied poor prognosis and relapse in gastrointestinal stromal tumors.
Zhuang C, Li X, Yang L, Ma X, Shen Y, Huang C, Pan T, Cui J, Ni B, Wang M
Frontiers in oncology 2023;13:1151687
Frontiers in oncology 2023;13:1151687
Bioengineered "Molecular Glue"-Mediated Tumor-Specific Cascade Nanoreactors with Self-Destruction Ability for Enhanced Precise Starvation/Chemosynergistic Tumor Therapy.
Zhang Q, Xuan Q, Wang C, Shi C, Wang X, Ma T, Zhang W, Li H, Wang P, Chen C
ACS applied materials & interfaces 2023 Sep 6;15(35):41271-41286
ACS applied materials & interfaces 2023 Sep 6;15(35):41271-41286
Knockdown of ANXA10 induces ferroptosis by inhibiting autophagy-mediated TFRC degradation in colorectal cancer.
Wang X, Zhou Y, Ning L, Chen J, Chen H, Li X
Cell death & disease 2023 Sep 4;14(9):588
Cell death & disease 2023 Sep 4;14(9):588
Yttrium chloride induces ferroptosis in cardiomyocytes via iron accumulation and triggers cardiac lipid peroxidation and inflammation that cause heart adverse events in mice.
Xiong L, Huang J, Wu C, Yuan Q, Wang S, Zhu L, Li Z, Sun Z, Fang Y, Li W, Hu G
Ecotoxicology and environmental safety 2023 Sep 15;263:115279
Ecotoxicology and environmental safety 2023 Sep 15;263:115279
Activation of Nrf2 signalling pathway by tectoridin protects against ferroptosis in particulate matter-induced lung injury.
Dong T, Fan X, Zheng N, Yan K, Hou T, Peng L, Ci X
British journal of pharmacology 2023 Oct;180(19):2532-2549
British journal of pharmacology 2023 Oct;180(19):2532-2549
Exogenous H(2)S initiating Nrf2/GPx4/GSH pathway through promoting Syvn1-Keap1 interaction in diabetic hearts.
Wang M, Tang J, Zhang S, Pang K, Zhao Y, Liu N, Huang J, Kang J, Dong S, Li H, Tian Z, Duan B, Lu F, Zhang W
Cell death discovery 2023 Oct 24;9(1):394
Cell death discovery 2023 Oct 24;9(1):394
Curcumin alleviates AFB1-induced nephrotoxicity in ducks: regulating mitochondrial oxidative stress, ferritinophagy, and ferroptosis.
Liu H, He Y, Gao X, Li T, Qiao B, Tang L, Lan J, Su Q, Ruan Z, Tang Z, Hu L
Mycotoxin research 2023 Nov;39(4):437-451
Mycotoxin research 2023 Nov;39(4):437-451
Hydrogen sulfide ameliorates endothelial dysfunction in aging arteries by regulating ferroptosis.
Miao Y, Zhang S, Liang Z, Wang Y, Tian D, Jin S, Guo Q, Xue H, Teng X, Xiao L, Wu Y
Nitric oxide : biology and chemistry 2023 Nov 1;140-141:77-90
Nitric oxide : biology and chemistry 2023 Nov 1;140-141:77-90
Loureirin C inhibits ferroptosis after cerebral ischemia reperfusion through regulation of the Nrf2 pathway in mice.
Liu Y, Mi Y, Wang Y, Meng Q, Xu L, Liu Y, Zhou D, Wang Y, Liang D, Li W, Li N, Hou Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 May;113:154729
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 May;113:154729
Artesunate, a new antimalarial clinical drug, exhibits potent anti-AML activity by targeting the ROS/Bim and TFRC/Fe(2+) pathways.
Liu Y, Li H, Luo Z, Yu Y, Yang J, Zhang M, Law BYK, Huang Z, Li W
British journal of pharmacology 2023 Mar;180(6):701-720
British journal of pharmacology 2023 Mar;180(6):701-720
Dihydroartemisinin-induced ferroptosis in acute myeloid leukemia: links to iron metabolism and metallothionein.
Grignano E, Cantero-Aguilar L, Tuerdi Z, Chabane T, Vazquez R, Johnson N, Zerbit J, Decroocq J, Birsen R, Fontenay M, Kosmider O, Chapuis N, Bouscary D
Cell death discovery 2023 Mar 17;9(1):97
Cell death discovery 2023 Mar 17;9(1):97
Thorium(IV) triggers ferroptosis through disrupting iron homeostasis and heme metabolism in the liver following oral ingestion.
Ma M, Wang R, Xu M
Journal of hazardous materials 2023 Jun 15;452:131217
Journal of hazardous materials 2023 Jun 15;452:131217
Palmitic acid-induced ferroptosis via CD36 activates ER stress to break calcium-iron balance in colon cancer cells.
Kuang H, Sun X, Liu Y, Tang M, Wei Y, Shi Y, Li R, Xiao G, Kang J, Wang F, Peng J, Xu H, Zhou F
The FEBS journal 2023 Jul;290(14):3664-3687
The FEBS journal 2023 Jul;290(14):3664-3687
ATM orchestrates ferritinophagy and ferroptosis by phosphorylating NCOA4.
Wu H, Liu Q, Shan X, Gao W, Chen Q
Autophagy 2023 Jul;19(7):2062-2077
Autophagy 2023 Jul;19(7):2062-2077
Hydrogen sulfide alleviates mitochondrial damage and ferroptosis by regulating OPA3-NFS1 axis in doxorubicin-induced cardiotoxicity.
Wang Y, Ying X, Wang Y, Zou Z, Yuan A, Xiao Z, Geng N, Qiao Z, Li W, Lu X, Pu J
Cellular signalling 2023 Jul;107:110655
Cellular signalling 2023 Jul;107:110655
Fucoxanthin triggers ferroptosis in glioblastoma cells by stabilizing the transferrin receptor.
Zhu Q, Zhou Y, Wang H, Cao T, Wang X, Liu R, Wu H, Lin B
Medical oncology (Northwood, London, England) 2023 Jul 8;40(8):230
Medical oncology (Northwood, London, England) 2023 Jul 8;40(8):230
Melatonin inhibits ferroptosis and delays age-related cataract by regulating SIRT6/p-Nrf2/GPX4 and SIRT6/NCOA4/FTH1 pathways.
Mi Y, Wei C, Sun L, Liu H, Zhang J, Luo J, Yu X, He J, Ge H, Liu P
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jan;157:114048
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jan;157:114048
Sphingosine 1-phosphate alleviates radiation-induced ferroptosis in ovarian granulosa cells by upregulating glutathione peroxidase 4.
Zhao J, Tang M, Tang H, Wang M, Guan H, Tang L, Zhang H
Reproductive toxicology (Elmsford, N.Y.) 2023 Jan;115:49-55
Reproductive toxicology (Elmsford, N.Y.) 2023 Jan;115:49-55
ATP6V0D1 promotes alkaliptosis by blocking STAT3-mediated lysosomal pH homeostasis.
Chen F, Zhu S, Kang R, Tang D, Liu J
Cell reports 2023 Jan 31;42(1):111911
Cell reports 2023 Jan 31;42(1):111911
Ferroptotic stress facilitates smooth muscle cell dedifferentiation in arterial remodelling by disrupting mitochondrial homeostasis.
Ji QX, Zeng FY, Zhou J, Wu WB, Wang XJ, Zhang Z, Zhang GY, Tong J, Sun DY, Zhang JB, Cao WX, Shen FM, Lu JJ, Li DJ, Wang P
Cell death and differentiation 2023 Feb;30(2):457-474
Cell death and differentiation 2023 Feb;30(2):457-474
Ferroptosis is involved in PM2.5-induced acute nasal epithelial injury via AMPK-mediated autophagy.
Gu W, Hou T, Zhou H, Zhu L, Zhu W, Wang Y
International immunopharmacology 2023 Feb;115:109658
International immunopharmacology 2023 Feb;115:109658
Ferroptosis is involved in corpus cavernosum smooth muscle cells impairment in diabetes mellitus-induced erectile dysfunction.
Xu W, Sun T, Wang J, Wang T, Wang S, Liu J, Liu K, Li H
Andrology 2023 Feb;11(2):332-343
Andrology 2023 Feb;11(2):332-343
Transferrin Receptor is Associated with Sensitivity to Ferroptosis Inducers in Hepatocellular Carcinoma.
Hiromatsu M, Toshida K, Itoh S, Harada N, Kohashi K, Oda Y, Yoshizumi T
Annals of surgical oncology 2023 Dec;30(13):8675-8689
Annals of surgical oncology 2023 Dec;30(13):8675-8689
Knockdown of SETD2 promotes erastin-induced ferroptosis in ccRCC.
Xue W, Jian W, Meng Y, Wang T, Cai L, Yu Y, Yu Y, Xia Z, Zhang C
Cell death & disease 2023 Aug 21;14(8):539
Cell death & disease 2023 Aug 21;14(8):539
Hormone replacement therapy for postmenopausal atherosclerosis is offset by late age iron deposition.
Xu T, Cai J, Wang L, Xu L, Zhao H, Wang F, Meyron-Holtz EG, Missirlis F, Qiao T, Li K
eLife 2023 Aug 10;12
eLife 2023 Aug 10;12
LncRNA modulates Hippo-YAP signaling to reprogram iron metabolism.
He XY, Fan X, Qu L, Wang X, Jiang L, Sang LJ, Shi CY, Lin S, Yang JC, Yang ZZ, Lei K, Li JH, Ju HQ, Yan Q, Liu J, Wang F, Shao J, Xiong Y, Wang W, Lin A
Nature communications 2023 Apr 20;14(1):2253
Nature communications 2023 Apr 20;14(1):2253
EPC-exosomal miR-26a-5p improves airway remodeling in COPD by inhibiting ferroptosis of bronchial epithelial cells via PTGS2/PGE2 signaling pathway.
Liu C, Lu J, Yuan T, Xie L, Zhang L
Scientific reports 2023 Apr 14;13(1):6126
Scientific reports 2023 Apr 14;13(1):6126
Cyclosporine A-loaded apoferritin alleviates myocardial ischemia-reperfusion injury by simultaneously blocking ferroptosis and apoptosis of cardiomyocytes.
Qian W, Liu D, Han Y, Liu M, Liu B, Ji Q, Zhang B, Mei Q, Zhou S, Cheng Y
Acta biomaterialia 2023 Apr 1;160:265-280
Acta biomaterialia 2023 Apr 1;160:265-280
Single-cell transcriptomics uncover the key ferroptosis regulators contribute to cancer progression in head and neck squamous cell carcinoma.
Liu F, Tang L, Li Q, Chen L, Pan Y, Yin Z, He J, Tian J
Frontiers in molecular biosciences 2022;9:962742
Frontiers in molecular biosciences 2022;9:962742
Role of TFRC as a Novel Prognostic Biomarker and in Immunotherapy for Pancreatic Carcinoma.
Yang C, Li J, Guo Y, Gan D, Zhang C, Wang R, Hua L, Zhu L, Ma P, Shi J, Li S, Su H
Frontiers in molecular biosciences 2022;9:756895
Frontiers in molecular biosciences 2022;9:756895
Exosomes derived from pericardial adipose tissues attenuate cardiac remodeling following myocardial infarction by Adipsin-regulated iron homeostasis.
Man W, Song X, Xiong Z, Gu J, Lin J, Gu X, Yu D, Li C, Jiang M, Zhang X, Yang Z, Cao Y, Zhang Y, Shu X, Wu D, Wang H, Ji G, Sun D
Frontiers in cardiovascular medicine 2022;9:1003282
Frontiers in cardiovascular medicine 2022;9:1003282
Hepatic TGFβr1 Deficiency Attenuates Lipopolysaccharide/D-Galactosamine-Induced Acute Liver Failure Through Inhibiting GSK3β-Nrf2-Mediated Hepatocyte Apoptosis and Ferroptosis.
Huang S, Wang Y, Xie S, Lai Y, Mo C, Zeng T, Kuang S, Deng G, Zhou C, Chen Y, Huang S, Gao L, Lv Z
Cellular and molecular gastroenterology and hepatology 2022;13(6):1649-1672
Cellular and molecular gastroenterology and hepatology 2022;13(6):1649-1672
Dexmedetomidine prevents hemorrhagic brain injury by reducing damage induced by ferroptosis in mice.
Liu MJ, Zhao XC, Gong HS, You YQ, Li JY
Neuroscience letters 2022 Sep 25;788:136842
Neuroscience letters 2022 Sep 25;788:136842
Phospholipid peroxidation-driven modification of chondrogenic transcription factor mediates alkoxyl radicals-induced impairment of embryonic bone development.
Niu J, Wan X, Yu GY, Jiang S, Yi RN, Wu YP, Ouyang SH, Liang L, Kurihara H, Sun WY, Zhu XF, Zhang RH, Cao YF, He JB, Duan WJ, Li YF, He RR
Redox biology 2022 Oct;56:102437
Redox biology 2022 Oct;56:102437
L-Citrulline Supplementation Restrains Ferritinophagy-Mediated Ferroptosis to Alleviate Iron Overload-Induced Thymus Oxidative Damage and Immune Dysfunction.
Ba T, Zhao D, Chen Y, Zeng C, Zhang C, Niu S, Dai H
Nutrients 2022 Oct 28;14(21)
Nutrients 2022 Oct 28;14(21)
Per1/Per2 knockout Affects Spleen Immune Function in Elderly Mice via Inducing Spleen Lymphocyte Ferroptosis.
He R, Zhang S, Yu J, Yu X, Wang J, Qiu Y, Zhou W, Wang F, Ren F, Liu Z
International journal of molecular sciences 2022 Oct 26;23(21)
International journal of molecular sciences 2022 Oct 26;23(21)
Farrerol alleviates collagenase-induced tendinopathy by inhibiting ferroptosis in rats.
Wu Y, Qian J, Li K, Li W, Yin W, Jiang H
Journal of cellular and molecular medicine 2022 Jun;26(12):3483-3494
Journal of cellular and molecular medicine 2022 Jun;26(12):3483-3494
Spatial region-resolved proteome map reveals mechanism of COVID-19-associated heart injury.
Leng L, Ma J, Zhang PP, Xu SC, Li X, Jin Y, Cai J, Tang R, Zhao L, He ZC, Li MS, Zhang H, Zhou LR, Wu ZH, Li TR, Zhu YP, Wang YJ, Wu HB, Ping YF, Yao XH, Zhu CH, Guo HT, Tan LY, Liang ZY, Bian XW, Zhang SY
Cell reports 2022 Jun 14;39(11):110955
Cell reports 2022 Jun 14;39(11):110955
ENO1 suppresses cancer cell ferroptosis by degrading the mRNA of iron regulatory protein 1.
Zhang T, Sun L, Hao Y, Suo C, Shen S, Wei H, Ma W, Zhang P, Wang T, Gu X, Li ST, Chen Z, Yan R, Zhang Y, Cai Y, Zhou R, Jia W, Huang F, Gao P, Zhang H
Nature cancer 2022 Jan;3(1):75-89
Nature cancer 2022 Jan;3(1):75-89
3D two-photon brain imaging reveals dihydroartemisinin exerts antiepileptic effects by modulating iron homeostasis.
Shao C, Liu Y, Chen Z, Qin Y, Wang X, Wang X, Yan C, Zhu HL, Zhao J, Qian Y
Cell chemical biology 2022 Jan 20;29(1):43-56.e12
Cell chemical biology 2022 Jan 20;29(1):43-56.e12
Lipid kinases VPS34 and PIKfyve coordinate a phosphoinositide cascade to regulate retriever-mediated recycling on endosomes.
Giridharan SSP, Luo G, Rivero-Rios P, Steinfeld N, Tronchere H, Singla A, Burstein E, Billadeau DD, Sutton MA, Weisman LS
eLife 2022 Jan 18;11
eLife 2022 Jan 18;11
Aging is associated with increased brain iron through cortex-derived hepcidin expression.
Sato T, Shapiro JS, Chang HC, Miller RA, Ardehali H
eLife 2022 Jan 11;11
eLife 2022 Jan 11;11
Iron transport across the human placenta is regulated by hepcidin.
McDonald EA, Gundogan F, Olveda RM, Bartnikas TB, Kurtis JD, Friedman JF
Pediatric research 2022 Aug;92(2):396-402
Pediatric research 2022 Aug;92(2):396-402
Leonurine alleviates ferroptosis in cisplatin-induced acute kidney injury by activating the Nrf2 signalling pathway.
Hu J, Gu W, Ma N, Fan X, Ci X
British journal of pharmacology 2022 Aug;179(15):3991-4009
British journal of pharmacology 2022 Aug;179(15):3991-4009
The role of ferritin and iron dextran in exacerbating preeclampsia in an L-NAME-treated rat model.
Zhu X, Jiang R, Ying X, Li Z, Jiang P
Annals of translational medicine 2022 Aug;10(16):889
Annals of translational medicine 2022 Aug;10(16):889
The Ferroptosis-NLRP1 Inflammasome: The Vicious Cycle of an Adverse Pregnancy.
Meihe L, Shan G, Minchao K, Xiaoling W, Peng A, Xili W, Jin Z, Huimin D
Frontiers in cell and developmental biology 2021;9:707959
Frontiers in cell and developmental biology 2021;9:707959
WDR45 Mutation Impairs the Autophagic Degradation of Transferrin Receptor and Promotes Ferroptosis.
Xiong Q, Li X, Li W, Chen G, Xiao H, Li P, Wu C
Frontiers in molecular biosciences 2021;8:645831
Frontiers in molecular biosciences 2021;8:645831
Ferroportin-Dependent Iron Homeostasis Protects against Oxidative Stress-Induced Nucleus Pulposus Cell Ferroptosis and Ameliorates Intervertebral Disc Degeneration In Vivo.
Lu S, Song Y, Luo R, Li S, Li G, Wang K, Liao Z, Wang B, Ke W, Xiang Q, Chen C, Wu X, Zhang Y, Ling L, Yang C
Oxidative medicine and cellular longevity 2021;2021:6670497
Oxidative medicine and cellular longevity 2021;2021:6670497
Oxalate Activates Autophagy to Induce Ferroptosis of Renal Tubular Epithelial Cells and Participates in the Formation of Kidney Stones.
Song Q, Liao W, Chen X, He Z, Li D, Li B, Liu J, Liu L, Xiong Y, Song C, Yang S
Oxidative medicine and cellular longevity 2021;2021:6630343
Oxidative medicine and cellular longevity 2021;2021:6630343
The blood-brain barrier studied in vitro across species.
Thomsen MS, Humle N, Hede E, Moos T, Burkhart A, Thomsen LB
PloS one 2021;16(3):e0236770
PloS one 2021;16(3):e0236770
Dipetidyl peptidase-4 and transferrin receptor serve as prognostic biomarkers for acute myeloid leukemia.
Wei J, Nai GY, Dai Y, Huang XJ, Xiong MY, Yao XY, Huang ZN, Li SN, Zhou WJ, Huang Y, Cheng P, Deng DH
Annals of translational medicine 2021 Sep;9(17):1381
Annals of translational medicine 2021 Sep;9(17):1381
The metabolite α-KG induces GSDMC-dependent pyroptosis through death receptor 6-activated caspase-8.
Zhang JY, Zhou B, Sun RY, Ai YL, Cheng K, Li FN, Wang BR, Liu FJ, Jiang ZH, Wang WJ, Zhou D, Chen HZ, Wu Q
Cell research 2021 Sep;31(9):980-997
Cell research 2021 Sep;31(9):980-997
Chitosan-based nanoparticle co-delivery of docetaxel and curcumin ameliorates anti-tumor chemoimmunotherapy in lung cancer.
Zhu X, Yu Z, Feng L, Deng L, Fang Z, Liu Z, Li Y, Wu X, Qin L, Guo R, Zheng Y
Carbohydrate polymers 2021 Sep 15;268:118237
Carbohydrate polymers 2021 Sep 15;268:118237
Atractylodin may induce ferroptosis of human hepatocellular carcinoma cells.
He Y, Fang D, Liang T, Pang H, Nong Y, Tang L, Yang Z, Lu C, Han X, Zhao S, Mo S, Meng Y, Han C, Peng T
Annals of translational medicine 2021 Oct;9(20):1535
Annals of translational medicine 2021 Oct;9(20):1535
Seizure-mediated iron accumulation and dysregulated iron metabolism after status epilepticus and in temporal lobe epilepsy.
Zimmer TS, David B, Broekaart DWM, Schidlowski M, Ruffolo G, Korotkov A, van der Wel NN, van Rijen PC, Mühlebner A, van Hecke W, Baayen JC, Idema S, François L, van Eyll J, Dedeurwaerdere S, Kessels HW, Surges R, Rüber T, Gorter JA, Mills JD, van Vliet EA, Aronica E
Acta neuropathologica 2021 Oct;142(4):729-759
Acta neuropathologica 2021 Oct;142(4):729-759
LPS-induced macrophage HMGB1-loaded extracellular vesicles trigger hepatocyte pyroptosis by activating the NLRP3 inflammasome.
Wang G, Jin S, Huang W, Li Y, Wang J, Ling X, Huang Y, Hu Y, Li C, Meng Y, Li X
Cell death discovery 2021 Nov 6;7(1):337
Cell death discovery 2021 Nov 6;7(1):337
Nuciferine protects against folic acid-induced acute kidney injury by inhibiting ferroptosis.
Li D, Liu B, Fan Y, Liu M, Han B, Meng Y, Xu X, Song Z, Liu X, Hao Q, Duan X, Nakai A, Chang Y, Cao P, Tan K
British journal of pharmacology 2021 Mar;178(5):1182-1199
British journal of pharmacology 2021 Mar;178(5):1182-1199
Tolerable upper intake level of iron damages the liver of weaned piglets.
Ding H, Zhao Y, Yu X, Chen L, Han J, Feng J
Journal of animal physiology and animal nutrition 2021 Jul;105(4):668-677
Journal of animal physiology and animal nutrition 2021 Jul;105(4):668-677
Tetrachlorobenzoquinone exposure triggers ferroptosis contributing to its neurotoxicity.
Liu Z, Lv X, Yang B, Qin Q, Song E, Song Y
Chemosphere 2021 Feb;264(Pt 1):128413
Chemosphere 2021 Feb;264(Pt 1):128413
LncRNA RP1-86C11.7 exacerbates the glioma progression and oncogenicity by hsa-miR-144-3p/TFRC signaling.
Ma Q, Wang X, Li J
Translational oncology 2021 Dec;14(12):101215
Translational oncology 2021 Dec;14(12):101215
A novel signature constructed by ferroptosis-associated genes (FAGs) for the prediction of prognosis in bladder urothelial carcinoma (BLCA) and associated with immune infiltration.
Luan JC, Zeng TY, Zhang QJ, Xia DR, Cong R, Yao LY, Song LB, Zhou X, Zhou X, Chen X, Xia JD, Song NH
Cancer cell international 2021 Aug 6;21(1):414
Cancer cell international 2021 Aug 6;21(1):414
Fostered Nrf2 expression antagonizes iron overload and glutathione depletion to promote resistance of neuron-like cells to ferroptosis.
Liu Z, Lv X, Song E, Song Y
Toxicology and applied pharmacology 2020 Nov 15;407:115241
Toxicology and applied pharmacology 2020 Nov 15;407:115241
Transferrin receptor 1 targeted optical imaging for identifying glioma margin in mouse models.
Ni XR, Zhao YY, Cai HP, Yu ZH, Wang J, Chen FR, Yu YJ, Feng GK, Chen ZP
Journal of neuro-oncology 2020 Jun;148(2):245-258
Journal of neuro-oncology 2020 Jun;148(2):245-258
miR-30-5p-mediated ferroptosis of trophoblasts is implicated in the pathogenesis of preeclampsia.
Zhang H, He Y, Wang JX, Chen MH, Xu JJ, Jiang MH, Feng YL, Gu YF
Redox biology 2020 Jan;29:101402
Redox biology 2020 Jan;29:101402
A novel iron(II) phenanthroline complex exhibits anticancer activity against TFR1-overexpressing esophageal squamous cell carcinoma cells through ROS accumulation and DNA damage.
Ye J, Ma J, Liu C, Huang J, Wang L, Zhong X
Biochemical pharmacology 2019 Aug;166:93-107
Biochemical pharmacology 2019 Aug;166:93-107
Mutant huntingtin induces iron overload via up-regulating IRP1 in Huntington's disease.
Niu L, Ye C, Sun Y, Peng T, Yang S, Wang W, Li H
Cell & bioscience 2018;8:41
Cell & bioscience 2018;8:41
Retention of Mitochondria in Mature Human Red Blood Cells as the Result of Autophagy Impairment in Rett Syndrome.
Sbardella D, Tundo GR, Campagnolo L, Valacchi G, Orlandi A, Curatolo P, Borsellino G, D'Esposito M, Ciaccio C, Cesare SD, Pierro DD, Galasso C, Santarone ME, Hayek J, Coletta M, Marini S
Scientific reports 2017 Sep 26;7(1):12297
Scientific reports 2017 Sep 26;7(1):12297
FBW7 increases the chemosensitivity of pancreatic cancer cells to gemcitabine through upregulation of ENT1.
Hu Q, Qin Y, Zhang B, Liang C, Ji S, Shi S, Xu W, Xiang J, Liang D, Ni Q, Yu X, Xu J
Oncology reports 2017 Oct;38(4):2069-2077
Oncology reports 2017 Oct;38(4):2069-2077
Long-Term Dexamethasone Exposure Down-Regulates Hepatic TFR1 and Reduces Liver Iron Concentration in Rats.
Li H, Jiang S, Yang C, Yang S, He B, Ma W, Zhao R
Nutrients 2017 Jun 17;9(6)
Nutrients 2017 Jun 17;9(6)
Myricetin ameliorates scopolamine-induced memory impairment in mice via inhibiting acetylcholinesterase and down-regulating brain iron.
Wang B, Zhong Y, Gao C, Li J
Biochemical and biophysical research communications 2017 Aug 19;490(2):336-342
Biochemical and biophysical research communications 2017 Aug 19;490(2):336-342
Maternal protein restriction depresses the duodenal expression of iron transporters and serum iron level in male weaning piglets.
Ma W, Lu J, Jiang S, Cai D, Pan S, Jia Y, Zhao R
The British journal of nutrition 2017 Apr;117(7):923-929
The British journal of nutrition 2017 Apr;117(7):923-929
Intracellular Released Payload Influences Potency and Bystander-Killing Effects of Antibody-Drug Conjugates in Preclinical Models.
Li F, Emmerton KK, Jonas M, Zhang X, Miyamoto JB, Setter JR, Nicholas ND, Okeley NM, Lyon RP, Benjamin DR, Law CL
Cancer research 2016 May 1;76(9):2710-9
Cancer research 2016 May 1;76(9):2710-9
Liver metal levels and expression of genes related to iron homeostasis in rhesus monkeys after inhalational manganese exposure.
Pettiglio MA, Herrera C, Foster ML, Dorman DC, Bartnikas TB
Data in brief 2016 Mar;6:989-97
Data in brief 2016 Mar;6:989-97
Iron homeostasis and its disruption in mouse lung in iron deficiency and overload.
Giorgi G, D'Anna MC, Roque ME
Experimental physiology 2015 Oct;100(10):1199-216
Experimental physiology 2015 Oct;100(10):1199-216
Dysregulated iron metabolism in the choroid plexus in fragile X-associated tremor/ataxia syndrome.
Ariza J, Steward C, Rueckert F, Widdison M, Coffman R, Afjei A, Noctor SC, Hagerman R, Hagerman P, Martínez-Cerdeño V
Brain research 2015 Feb 19;1598:88-96
Brain research 2015 Feb 19;1598:88-96
Mono-ubiquitylated ORF45 Mediates Association of KSHV Particles with Internal Lipid Rafts for Viral Assembly and Egress.
Wang X, Zhu N, Li W, Zhu F, Wang Y, Yuan Y
PLoS pathogens 2015 Dec;11(12):e1005332
PLoS pathogens 2015 Dec;11(12):e1005332
Adaptor protein complex 2-mediated, clathrin-dependent endocytosis, and related gene activities, are a prominent feature during maturation stage amelogenesis.
Lacruz RS, Brookes SJ, Wen X, Jimenez JM, Vikman S, Hu P, White SN, Lyngstadaas SP, Okamoto CT, Smith CE, Paine ML
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2013 Mar;28(3):672-87
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2013 Mar;28(3):672-87
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K
Journal of proteomics 2013 Mar 27;80:171-82
Journal of proteomics 2013 Mar 27;80:171-82
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- MCF7 cells were subjected to SDS PAGE followed by western blot with 10084-2-AP(CD71 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human placenta using 10084-2-AP(CD71 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Transferrin receptor/CD71 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Transferrin receptor/CD71. This antibody recognizes human,mouse,rat antigen. The Transferrin receptor/CD71 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
