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- References [177]
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- Product number
- 10084-2-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10084-2-AP, RRID:AB_2240403
- Product name
- CD71 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated CD71 antibody (Cat. #10084-2-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Liquiritigenin targets transferrin receptor to potentiate ferroptosis sensitivity in colorectal cancer cells.
Integrating spatial and single-cell transcriptomics analysis reveals MYCN-UBE2C-TFRC signaling endows ferroptosis resistance in neuroectodermal tumors.
RELA as a Diagnostic Biomarker for Parkinson's Disease by Integrating Ferroptosis, Lipid Metabolism, and Neuroinflammation.
ZDBF2/SIRT6-mediated H3K27 deacetylation inhibits ferroptosis and reduces sensitivity of oral squamous cell carcinoma to cisplatin.
Cancer cell membrane and iRGD peptide co-modified cantharidin liposomes for targeted therapy and immunotherapy of triple-negative breast cancer.
MC1R contributes to ferroptosis resistance and tumor aggressiveness in colorectal cancer by activating Notch signaling.
Integrated proteomic and metabolomic analysis reveals lipid metabolic dysregulation and ferroptosis as potential drivers of placental dysfunction in intrahepatic cholestasis of pregnancy.
Radiotherapy combined with anti-PD-1 immunotherapy promotes ferroptosis-driven control of hepatocellular carcinoma.
Iron homeostasis: effects of different levels of protein iron on placental iron handling in sows.
Succinylation modification on NFS1 ameliorates the glucose starvation-induced ferroptosis through maintaining mitochondrial iron homeostasis in oral squamous cell carcinoma cells.
PROTAC-Surufatinib Suppresses Pancreatic Neuroendocrine Neoplasms Progression by Inducing Ferroptosis through Inhibiting WNT/β-catenin Pathway Mediated by HMOX1.
CMSP exerts anti-tumor effects on small cell lung cancer cells by inducing mitochondrial dysfunction and ferroptosis.
Microplastic exposure induces preeclampsia-like symptoms via HIF-1α/TFRC-mediated ferroptosis in placental trophoblast cells.
miR-210-3p Ameliorates Metabolic Dysfunction-Associated Steatohepatitis-Related Fibrosis by Targeting ISCU and Induces Ferroptosis.
Unraveling the molecular mechanisms of paraquat toxicity: The interplay of ATF4, ferroptosis, and endoplasmic reticulum stress.
Formononetin enhances cisplatin chemotherapy sensitivity in osteosarcoma by inducing ferroptosis and reconstructing the immune microenvironment.
Genome-wide mapping of RNA-protein associations through sequencing.
Propionate alleviated colitis by modulating iron homeostasis to inhibit ferroptosis and macrophage polarization.
3-hydroxyanthranilic acid analog mitigates ischemia-reperfusion injury by inhibiting cardiomyocyte ferroptosis through the activation of Nrf2/HO-1/GPX4.
NOX4 Regulates NLRP3 by Inhibiting the Ubiquitination of LRRC8A to Promote Ferroptosis in Nucleus Pulposus Cells.
Transferrin receptor 1 is an entry factor for Japanese encephalitis virus.
Cancer-associated fibroblasts expressing FSTL3 promote vasculogenic mimicry formation and drive colon cancer malignancy.
Oxidative Stress and Iron Addiction: A Comparative Study of 1321N1 Astrocytoma and T98G Glioblastoma Cells with Differential Expression of L-Cysteine-Metabolizing Enzymes.
Analysis of the Correlation Between Depression-like Behaviors and Lipid Peroxidation in the Prefrontal Cortex of Mice: The Impact of Early Life Stress.
ARID1A loss enhances sensitivity to c-MET inhibition by dual targeting of GPX4 and iron homeostasis, inducing ferroptosis.
Systemic aldehyde storm induced by allyl alcohol exposure results in extensive hepatic ferroptosis in Aldh2∗2 knock-in mice.
Gambogic acid induces ferroptosis and suppresses colorectal cancer progression by modulating the m6A modification of p62.
A novel biomimetic nanoplatform amplifies ferroptosis for specific cGAS-STING pathway activation to enhance hepatocellular carcinoma chemo-immunotherapy.
Elucidating a novel prognostic signature for bladder cancer by integrating hypoxia and lactate metabolism-related genes: comprehensive bioinformatics analyses and experimental evidence.
CDC26 facilitates ferroptosis through SLC7A11 degradation and cell cycle arrest.
B355252 Targets UCP2 to Rescue Intracerebral Hemorrhage-Induced Injury by Promoting Mitochondrial Fusion and Inhibiting Ferroptosis.
Synergetic contributions of Seneca Valley virus 3 C and 3D proteins to induction of ferroptosis for viral replication.
Targeting PIM1 by Bruceine D attenuates skin fibrosis via myofibroblast ferroptosis.
Sirt1 overexpression inhibits chondrocyte ferroptosis via Ftl deacetylation to suppress the development of osteoarthritis.
Heterogeneity of fibroblasts from different anatomical sites in healthy human knee ligaments revealed by single-cell RNA sequencing.
Astragenol alleviates neuroinflammation and improves Parkinson's symptoms through amino acid metabolism pathway and inhibition of ferroptosis.
The anti-Alzheimer's disease effects of ganoderic acid A by inhibiting ferroptosis-lipid peroxidation via activation of the NRF2/SLC7A11/GPX4 signaling pathway.
The Lactate-Primed KAT8‒PCK2 Axis Exacerbates Hepatic Ferroptosis During Ischemia/Reperfusion Injury by Reprogramming OXSM-Dependent Mitochondrial Fatty Acid Synthesis.
Gallic acid alleviates ferroptosis by negatively regulating APOC3 and improves nerve function deficit caused by traumatic brain injury.
Monounsaturated fatty acids promote cancer radioresistance by inhibiting ferroptosis through ACSL3.
Acid sphingomyelinase recruits palmitoylated CD36 to membrane rafts and enhances lipid uptake.
MiR214-3p Ameliorates Diabetic Cardiomyopathy by Inhibiting Ferroptosis.
Two novel SH3TC2 mutations predispose to Charcot-Marie-Tooth disease type 4C by mistargeting away from TFRC.
ESRP1 exerts anti-tumor role by promoting ferroptosis in diffuse-type gastric cancer.
Fucoxanthin Ameliorates Carbon Tetrachloride-Induced Liver Fibrosis in Mice via Nrf2/HO-1/GPX4-Mediated Ferroptosis Pathway.
Heat shock protein B1-mediated ferroptosis regulates mitochondrial dysfunction in adipose tissue of ketotic dairy cows.
Human β-casein-derived peptide BCCY-1 improved the intestinal barrier integrity by regulating the TLR4/eNOS/3-Nitrotyrosine axis.
Testosterone deficiency aggravates diet-induced non-alcoholic fatty liver disease by inducing hepatocyte ferroptosis via targeting BMAL1 in mice.
Bergenin inhibits ferritinophagy and ferroptosis in cisplatin-induced acute kidney injury by activating the p-GSK3β/Nrf2/PPARγ pathway.
Hesperetin alleviates PM2.5-induced lung injury by inhibiting ferroptosis in an Nrf2-dependent manner.
Integrated network pharmacology, bioinformatics, and experiment analysis to decipher the molecular mechanism of Salidroside on Gastric cancer via targeting NCOA4-mediated ferritinophagy.
Crucial roles of asprosin in cisplatin-induced ferroptosis and acute kidney injury.
Norepinephrine Induces Sertoli Cell Ferroptosis via Receptors Desensitization Causing Stress-Related Male Reproductive Dysfunction.
Exosomal miR-145-5p impairs neoadjuvant chemotherapy by suppressing TFRC-mediated macrophage iron uptake and driving M2 polarization in esophageal cancer.
Baicalein attenuates metabolic dysfunction-associated steatohepatitis by regulating macrophage ferroptosis through nuclear factor (erythroid-derived 2)-like 2 pathway.
Activation of AKT via a dual mechanism enhances the susceptibility of melanoma cells to glucose deprivation.
Hua Zheng San Ji Fang promotes ferroptosis through Keap1/Nrf2 pathway in hepatocellular carcinoma cells.
Role of ferroptosis mediated by abnormal membrane structure in DEHP-induced reproductive injury.
Targeting GPX4 alleviates ferroptosis and retards abdominal aortic aneurysm formation.
TAZ/NRF2 positive feedback loop contributes to proliferation in bladder cancer through antagonistic ferroptosis.
Artesunate induces ferroptosis in osteosarcoma through NCOA4-mediated ferritinophagy.
Triptolide Attenuates Renal Slit Diagram to Tight Junction Transition in Diabetic Kidney Disease by Regulating Nrf2-Ferroptosis Pathway.
Propofol and Dexmedetomidine Ameliorate Endotoxemia-Associated Encephalopathy via Inhibiting Ferroptosis.
Progressive iron overload in middle-aged mice impairs olfactory function, triggers lipid oxidation and induces apoptosis.
Daphnetin induces ferroptosis in ovarian cancer by inhibiting NAD(P)H:Quinone oxidoreductase 1 (NQO1).
Deferoxamine alleviates chondrocyte senescence and osteoarthritis progression by maintaining iron homeostasis.
Corilagin alleviates ferroptosis in diabetic retinopathy by activating the Nrf2 signaling pathway.
Proteomics reveals the pharmacological mechanism of flavonoids from Astragali Complanati Semen in preventing chronic liver injury.
Intra-articular injection of platinum nanozyme-loaded silk fibroin/pullulan hydrogels relieves osteoarthritis through ROS scavenging and ferroptosis suppression.
Novel biallelic variants in IREB2 cause an early-onset neurodegenerative disorder in a Chinese pedigree.
Platycodin D ameliorates polycystic ovary syndrome-induced ovarian damage by upregulating CD44 to attenuate ferroptosis.
Dampening of ISGylation of RIG-I by ADAP regulates type I interferon response of macrophages to RNA virus infection.
Injectable, anti-collapse, adhesive, plastic and bioactive bone graft substitute promotes bone regeneration by moderating oxidative stress in osteoporotic bone defect.
Kinase PIM1 governs ferroptosis to reduce retinal microvascular endothelial cell dysfunction triggered by high glucose.
Glioma-targeted oxaliplatin/ferritin clathrate reversing the immunosuppressive microenvironment through hijacking Fe(2+) and boosting Fenton reaction.
Nicorandil Regulates Ferroptosis and Mitigates Septic Cardiomyopathy via TLR4/SLC7A11 Signaling Pathway.
Anti-tumor immunotherapy using engineered bacterial outer membrane vesicles fused to lysosome-targeting chimeras mediated by transferrin receptor.
Mitoferrin2 is a synthetic lethal target for chromosome 8p deleted cancers.
Neurotoxicity of manganese via ferroptosis induced by redox imbalance and iron overload.
Ciprofloxacin is a novel anti-ferroptotic antibiotic.
Salvia miltiorrhiza Bge. processed with porcine cardiac blood inhibited GLRX5-mediated ferroptosis alleviating cerebral ischemia-reperfusion injury.
Ambra1 in exosomes secreted by HK-2 cells damaged by supersaturated oxalate induce mitophagy and autophagy-ferroptosis in normal HK-2 cells to participate in the occurrence of kidney stones.
Transient receptor potential channel TRPM4 favors oxidized low-density lipoprotein-induced coronary endothelial cell dysfunction via a mechanism involving ferroptosis.
Heterogeneous ferroptosis susceptibility of macrophages caused by focal iron overload exacerbates rheumatoid arthritis.
The clustering status of detached gastric cancer cells inhibits anoikis-induced ferroptosis to promote metastatic colonization.
Pro-ferroptotic signaling promotes arterial aging via vascular smooth muscle cell senescence.
Inhibition of CDGSH iron‑sulfur domain 2 exhibits tumor-suppressing effects on diffuse large B-cell lymphoma (DLBCL) by inducing ferroptosis through the regulation of the NRF2/SLC7A11/GPX4 pathway.
Copper as the driver of the lncRNA-TCONS-6251/miR-novel-100/TC2N axis: Unraveling ferroptosis in duck kidney.
Network pharmacology, molecular docking and experimental study on the mechanism of Curcumin's anti-ferroptosis in melanocytes.
Melatonin protects against particulate matter-induced ovarian dysfunction by activating the Nrf2 signaling pathway to alleviate ferroptosis.
Chronic microcystin-leucine-arginine exposure induces osteoporosis by breaking the balance of osteoblasts and osteoclasts.
Effects on Iron Metabolism and System Xc- /GPX4 Pathway from Hydroquinone Suggest Ferroptosis of Jurkat Cells.
CCT3/ACTN4/TFRC axis protects hepatocellular carcinoma cells from ferroptosis by inhibiting iron endocytosis.
Bulk RNA-sequencing, single-cell RNA-sequencing analysis, and experimental validation reveal iron metabolism-related genes CISD2 and CYP17A1 are potential diagnostic markers for recurrent pregnancy loss.
Targeted delivery of MerTK protein via cell membrane engineered nanoparticle enhances efferocytosis and attenuates atherosclerosis in diabetic ApoE(-/-) Mice.
Targeted elimination of senescent cells by engineered extracellular vesicles attenuates atherosclerosis in ApoE(-/-) mice with minimal side effects.
Overexpressed transferrin receptor implied poor prognosis and relapse in gastrointestinal stromal tumors.
Bioengineered "Molecular Glue"-Mediated Tumor-Specific Cascade Nanoreactors with Self-Destruction Ability for Enhanced Precise Starvation/Chemosynergistic Tumor Therapy.
Exogenous spermidine alleviates diabetic cardiomyopathy via suppressing reactive oxygen species, endoplasmic reticulum stress, and Pannexin-1-mediated ferroptosis.
Knockdown of ANXA10 induces ferroptosis by inhibiting autophagy-mediated TFRC degradation in colorectal cancer.
Yttrium chloride induces ferroptosis in cardiomyocytes via iron accumulation and triggers cardiac lipid peroxidation and inflammation that cause heart adverse events in mice.
Activation of Nrf2 signalling pathway by tectoridin protects against ferroptosis in particulate matter-induced lung injury.
Exogenous H(2)S initiating Nrf2/GPx4/GSH pathway through promoting Syvn1-Keap1 interaction in diabetic hearts.
Heme-deficient primitive red blood cells induce HSPC ferroptosis by altering iron homeostasis during zebrafish embryogenesis.
Curcumin alleviates AFB1-induced nephrotoxicity in ducks: regulating mitochondrial oxidative stress, ferritinophagy, and ferroptosis.
Hydrogen sulfide ameliorates endothelial dysfunction in aging arteries by regulating ferroptosis.
Loureirin C inhibits ferroptosis after cerebral ischemia reperfusion through regulation of the Nrf2 pathway in mice.
Artesunate, a new antimalarial clinical drug, exhibits potent anti-AML activity by targeting the ROS/Bim and TFRC/Fe(2+) pathways.
Dihydroartemisinin-induced ferroptosis in acute myeloid leukemia: links to iron metabolism and metallothionein.
Thorium(IV) triggers ferroptosis through disrupting iron homeostasis and heme metabolism in the liver following oral ingestion.
Palmitic acid-induced ferroptosis via CD36 activates ER stress to break calcium-iron balance in colon cancer cells.
ATM orchestrates ferritinophagy and ferroptosis by phosphorylating NCOA4.
Hydrogen sulfide alleviates mitochondrial damage and ferroptosis by regulating OPA3-NFS1 axis in doxorubicin-induced cardiotoxicity.
Fucoxanthin triggers ferroptosis in glioblastoma cells by stabilizing the transferrin receptor.
Melatonin inhibits ferroptosis and delays age-related cataract by regulating SIRT6/p-Nrf2/GPX4 and SIRT6/NCOA4/FTH1 pathways.
Sphingosine 1-phosphate alleviates radiation-induced ferroptosis in ovarian granulosa cells by upregulating glutathione peroxidase 4.
ATP6V0D1 promotes alkaliptosis by blocking STAT3-mediated lysosomal pH homeostasis.
Ferroptotic stress facilitates smooth muscle cell dedifferentiation in arterial remodelling by disrupting mitochondrial homeostasis.
Ferroptosis is involved in PM2.5-induced acute nasal epithelial injury via AMPK-mediated autophagy.
Ferroptosis is involved in corpus cavernosum smooth muscle cells impairment in diabetes mellitus-induced erectile dysfunction.
Transferrin Receptor is Associated with Sensitivity to Ferroptosis Inducers in Hepatocellular Carcinoma.
Knockdown of SETD2 promotes erastin-induced ferroptosis in ccRCC.
Hormone replacement therapy for postmenopausal atherosclerosis is offset by late age iron deposition.
LncRNA modulates Hippo-YAP signaling to reprogram iron metabolism.
EPC-exosomal miR-26a-5p improves airway remodeling in COPD by inhibiting ferroptosis of bronchial epithelial cells via PTGS2/PGE2 signaling pathway.
Cyclosporine A-loaded apoferritin alleviates myocardial ischemia-reperfusion injury by simultaneously blocking ferroptosis and apoptosis of cardiomyocytes.
Single-cell transcriptomics uncover the key ferroptosis regulators contribute to cancer progression in head and neck squamous cell carcinoma.
Role of TFRC as a Novel Prognostic Biomarker and in Immunotherapy for Pancreatic Carcinoma.
Exosomes derived from pericardial adipose tissues attenuate cardiac remodeling following myocardial infarction by Adipsin-regulated iron homeostasis.
Hepatic TGFβr1 Deficiency Attenuates Lipopolysaccharide/D-Galactosamine-Induced Acute Liver Failure Through Inhibiting GSK3β-Nrf2-Mediated Hepatocyte Apoptosis and Ferroptosis.
Dexmedetomidine prevents hemorrhagic brain injury by reducing damage induced by ferroptosis in mice.
Phospholipid peroxidation-driven modification of chondrogenic transcription factor mediates alkoxyl radicals-induced impairment of embryonic bone development.
L-Citrulline Supplementation Restrains Ferritinophagy-Mediated Ferroptosis to Alleviate Iron Overload-Induced Thymus Oxidative Damage and Immune Dysfunction.
Per1/Per2 knockout Affects Spleen Immune Function in Elderly Mice via Inducing Spleen Lymphocyte Ferroptosis.
Farrerol alleviates collagenase-induced tendinopathy by inhibiting ferroptosis in rats.
Spatial region-resolved proteome map reveals mechanism of COVID-19-associated heart injury.
ENO1 suppresses cancer cell ferroptosis by degrading the mRNA of iron regulatory protein 1.
3D two-photon brain imaging reveals dihydroartemisinin exerts antiepileptic effects by modulating iron homeostasis.
Lipid kinases VPS34 and PIKfyve coordinate a phosphoinositide cascade to regulate retriever-mediated recycling on endosomes.
Aging is associated with increased brain iron through cortex-derived hepcidin expression.
Iron transport across the human placenta is regulated by hepcidin.
Leonurine alleviates ferroptosis in cisplatin-induced acute kidney injury by activating the Nrf2 signalling pathway.
The role of ferritin and iron dextran in exacerbating preeclampsia in an L-NAME-treated rat model.
The Ferroptosis-NLRP1 Inflammasome: The Vicious Cycle of an Adverse Pregnancy.
WDR45 Mutation Impairs the Autophagic Degradation of Transferrin Receptor and Promotes Ferroptosis.
Ferroportin-Dependent Iron Homeostasis Protects against Oxidative Stress-Induced Nucleus Pulposus Cell Ferroptosis and Ameliorates Intervertebral Disc Degeneration In Vivo.
Oxalate Activates Autophagy to Induce Ferroptosis of Renal Tubular Epithelial Cells and Participates in the Formation of Kidney Stones.
The blood-brain barrier studied in vitro across species.
Dipetidyl peptidase-4 and transferrin receptor serve as prognostic biomarkers for acute myeloid leukemia.
The metabolite α-KG induces GSDMC-dependent pyroptosis through death receptor 6-activated caspase-8.
Chitosan-based nanoparticle co-delivery of docetaxel and curcumin ameliorates anti-tumor chemoimmunotherapy in lung cancer.
Atractylodin may induce ferroptosis of human hepatocellular carcinoma cells.
Seizure-mediated iron accumulation and dysregulated iron metabolism after status epilepticus and in temporal lobe epilepsy.
LPS-induced macrophage HMGB1-loaded extracellular vesicles trigger hepatocyte pyroptosis by activating the NLRP3 inflammasome.
Nuciferine protects against folic acid-induced acute kidney injury by inhibiting ferroptosis.
Tolerable upper intake level of iron damages the liver of weaned piglets.
Tetrachlorobenzoquinone exposure triggers ferroptosis contributing to its neurotoxicity.
LncRNA RP1-86C11.7 exacerbates the glioma progression and oncogenicity by hsa-miR-144-3p/TFRC signaling.
Ferroptosis inducer erastin sensitizes NSCLC cells to celastrol through activation of the ROS-mitochondrial fission-mitophagy axis.
A novel signature constructed by ferroptosis-associated genes (FAGs) for the prediction of prognosis in bladder urothelial carcinoma (BLCA) and associated with immune infiltration.
Fostered Nrf2 expression antagonizes iron overload and glutathione depletion to promote resistance of neuron-like cells to ferroptosis.
Transferrin receptor 1 targeted optical imaging for identifying glioma margin in mouse models.
miR-30-5p-mediated ferroptosis of trophoblasts is implicated in the pathogenesis of preeclampsia.
A novel iron(II) phenanthroline complex exhibits anticancer activity against TFR1-overexpressing esophageal squamous cell carcinoma cells through ROS accumulation and DNA damage.
Mutant huntingtin induces iron overload via up-regulating IRP1 in Huntington's disease.
Retention of Mitochondria in Mature Human Red Blood Cells as the Result of Autophagy Impairment in Rett Syndrome.
FBW7 increases the chemosensitivity of pancreatic cancer cells to gemcitabine through upregulation of ENT1.
Long-Term Dexamethasone Exposure Down-Regulates Hepatic TFR1 and Reduces Liver Iron Concentration in Rats.
Myricetin ameliorates scopolamine-induced memory impairment in mice via inhibiting acetylcholinesterase and down-regulating brain iron.
Maternal protein restriction depresses the duodenal expression of iron transporters and serum iron level in male weaning piglets.
Intracellular Released Payload Influences Potency and Bystander-Killing Effects of Antibody-Drug Conjugates in Preclinical Models.
Liver metal levels and expression of genes related to iron homeostasis in rhesus monkeys after inhalational manganese exposure.
Iron homeostasis and its disruption in mouse lung in iron deficiency and overload.
Dysregulated iron metabolism in the choroid plexus in fragile X-associated tremor/ataxia syndrome.
Mono-ubiquitylated ORF45 Mediates Association of KSHV Particles with Internal Lipid Rafts for Viral Assembly and Egress.
Adaptor protein complex 2-mediated, clathrin-dependent endocytosis, and related gene activities, are a prominent feature during maturation stage amelogenesis.
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Li R, Song C, Jia T, Xia T, Guo M, Wang Q, Yao Y, Xu X, Bao X, Yang P, Li Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158057
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158057
Integrating spatial and single-cell transcriptomics analysis reveals MYCN-UBE2C-TFRC signaling endows ferroptosis resistance in neuroectodermal tumors.
Yang J, He M, Liao Q, Mengjiang R, Li Y, Zong C, Zhu T, He F, Chai P, Jia R, Wen X, Fan X, Fan J
Science China. Life sciences 2026 Mar 26;
Science China. Life sciences 2026 Mar 26;
RELA as a Diagnostic Biomarker for Parkinson's Disease by Integrating Ferroptosis, Lipid Metabolism, and Neuroinflammation.
Chen Q, Jing Y, Bu W, Zhang J, Liu W, Shi C, Liu C, Su D
Inflammation 2026 Mar 11;49(1)
Inflammation 2026 Mar 11;49(1)
ZDBF2/SIRT6-mediated H3K27 deacetylation inhibits ferroptosis and reduces sensitivity of oral squamous cell carcinoma to cisplatin.
Liu K, Rong L, Shuai Y, Mu R, Ding H, Chen B, Jin L
Pathology, research and practice 2026 Jun;282:156419
Pathology, research and practice 2026 Jun;282:156419
Cancer cell membrane and iRGD peptide co-modified cantharidin liposomes for targeted therapy and immunotherapy of triple-negative breast cancer.
Guo Q, Wang S, Zhong Z, Zhou L, Xia X
Free radical biology & medicine 2026 Jun;249:273-291
Free radical biology & medicine 2026 Jun;249:273-291
MC1R contributes to ferroptosis resistance and tumor aggressiveness in colorectal cancer by activating Notch signaling.
Zeng X, Jiang L, Li H, Wang J, He X
Cancer gene therapy 2026 Jan;33(1):26-38
Cancer gene therapy 2026 Jan;33(1):26-38
Integrated proteomic and metabolomic analysis reveals lipid metabolic dysregulation and ferroptosis as potential drivers of placental dysfunction in intrahepatic cholestasis of pregnancy.
Dong R, Wang G, Shi Y, Gao J, Hu W, Zhang T
Biochimica et biophysica acta. Molecular and cell biology of lipids 2026 Jan;1871(1):159692
Biochimica et biophysica acta. Molecular and cell biology of lipids 2026 Jan;1871(1):159692
Radiotherapy combined with anti-PD-1 immunotherapy promotes ferroptosis-driven control of hepatocellular carcinoma.
Dou T, Zhu X, Li H, Wang R, He J, Geng H, Zhang W, Yu Q, Zhao H, Yang H
Genes and immunity 2026 Feb;27(1):91-105
Genes and immunity 2026 Feb;27(1):91-105
Iron homeostasis: effects of different levels of protein iron on placental iron handling in sows.
Wu D, Nie J, Zhou S, Liu L, Wang L, Yang S, Peng J, Tan C
The Journal of nutritional biochemistry 2026 Feb;148:110141
The Journal of nutritional biochemistry 2026 Feb;148:110141
Succinylation modification on NFS1 ameliorates the glucose starvation-induced ferroptosis through maintaining mitochondrial iron homeostasis in oral squamous cell carcinoma cells.
Ling H, Qing L, Zuo L, Wang H, Cai X, Liu Y, Tian H
Biochimica et biophysica acta. Molecular basis of disease 2026 Apr 23;1872(6):168276
Biochimica et biophysica acta. Molecular basis of disease 2026 Apr 23;1872(6):168276
PROTAC-Surufatinib Suppresses Pancreatic Neuroendocrine Neoplasms Progression by Inducing Ferroptosis through Inhibiting WNT/β-catenin Pathway Mediated by HMOX1.
Xue B, Yan L, Ye M, Gu D, Qian J, He N, Hu P, Lu F, Lu X, Liu M, Xu L, Bai J, Wang Y, Zhu G, Tang Q
International journal of biological sciences 2025;21(6):2476-2492
International journal of biological sciences 2025;21(6):2476-2492
CMSP exerts anti-tumor effects on small cell lung cancer cells by inducing mitochondrial dysfunction and ferroptosis.
Yan X, Niu Y, Wang Y, Wei S, Han L, Guo Z, Zhao L, Gao F
Open medicine (Warsaw, Poland) 2025;20(1):20241100
Open medicine (Warsaw, Poland) 2025;20(1):20241100
Microplastic exposure induces preeclampsia-like symptoms via HIF-1α/TFRC-mediated ferroptosis in placental trophoblast cells.
Jia H, Liu S, Wang W, He P, Zhao F, Xu X
Toxicology 2025 Sep;516:154197
Toxicology 2025 Sep;516:154197
miR-210-3p Ameliorates Metabolic Dysfunction-Associated Steatohepatitis-Related Fibrosis by Targeting ISCU and Induces Ferroptosis.
Dai Z, Sun Z, Chen Q, Li Y, Sun Y, Jiao M, Yin X, Liu R, Liang H, Zhu C
Liver international : official journal of the International Association for the Study of the Liver 2025 Sep;45(9):e70282
Liver international : official journal of the International Association for the Study of the Liver 2025 Sep;45(9):e70282
Unraveling the molecular mechanisms of paraquat toxicity: The interplay of ATF4, ferroptosis, and endoplasmic reticulum stress.
Ke J, Cai Q, Ge X, Zhang S
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Sep;203:115602
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Sep;203:115602
Formononetin enhances cisplatin chemotherapy sensitivity in osteosarcoma by inducing ferroptosis and reconstructing the immune microenvironment.
Liu Y, Xie T, Liang J, Feng W, Yang M, Li S, Xiong L, Luo K, Li F, Tang S, Liu S, Huang Q, Tang H, Tang F, Wei Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:156960
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:156960
Genome-wide mapping of RNA-protein associations through sequencing.
Qi Z, Xue S, Chen J, Zhao W, Johnson K, Wen X, Charles Richard JL, Lin P, Zhong S
Nature biotechnology 2025 Sep 9;
Nature biotechnology 2025 Sep 9;
Propionate alleviated colitis by modulating iron homeostasis to inhibit ferroptosis and macrophage polarization.
Yao T, Dong X, Lv J, Fu L, Li L
International immunopharmacology 2025 Sep 23;162:115151
International immunopharmacology 2025 Sep 23;162:115151
3-hydroxyanthranilic acid analog mitigates ischemia-reperfusion injury by inhibiting cardiomyocyte ferroptosis through the activation of Nrf2/HO-1/GPX4.
Yang HY, Liu ZY, Xu ZQ, Teng LS, Sheng XH, Zhang G, Zhang FS
International immunopharmacology 2025 Sep 23;162:115117
International immunopharmacology 2025 Sep 23;162:115117
NOX4 Regulates NLRP3 by Inhibiting the Ubiquitination of LRRC8A to Promote Ferroptosis in Nucleus Pulposus Cells.
Zhang F, Cui D, Wang Z, Li Y, Wang K, Lu H, Yu H, Jiao W, Cui X
Inflammation 2025 Oct;48(5):3111-3129
Inflammation 2025 Oct;48(5):3111-3129
Transferrin receptor 1 is an entry factor for Japanese encephalitis virus.
Yang Q, Xie S, Zhao Y, Lin X, Wei N, Shi M, Cao R
Veterinary microbiology 2025 Oct;309:110698
Veterinary microbiology 2025 Oct;309:110698
Cancer-associated fibroblasts expressing FSTL3 promote vasculogenic mimicry formation and drive colon cancer malignancy.
Ying L, Zhu Y, Zhang L, Ji M, Wang M, Dong L, Yun Z, Chen Y, Zhou J, Huang C, Zhang S, Yang X, Yang H, Huang G, Qin S, Xie J, Liu L
Cell death & disease 2025 Oct 6;16(1):706
Cell death & disease 2025 Oct 6;16(1):706
Oxidative Stress and Iron Addiction: A Comparative Study of 1321N1 Astrocytoma and T98G Glioblastoma Cells with Differential Expression of L-Cysteine-Metabolizing Enzymes.
Jurkowska H, Jasek-Gajda E, Kaleta K, Rydz L, Szlęzak D, Wróbel M
Biomolecules 2025 Oct 20;15(10)
Biomolecules 2025 Oct 20;15(10)
Analysis of the Correlation Between Depression-like Behaviors and Lipid Peroxidation in the Prefrontal Cortex of Mice: The Impact of Early Life Stress.
Mi X, Ye ZL, Zhang XJ, Dai XM, Luo ZS
Brain sciences 2025 Oct 15;15(10)
Brain sciences 2025 Oct 15;15(10)
ARID1A loss enhances sensitivity to c-MET inhibition by dual targeting of GPX4 and iron homeostasis, inducing ferroptosis.
Zhang X, Wang Z, He Y, Wang K, Xiang C, Liu Y, Song Y, Li A, Wang Z, Yu Y, Peng W, Liu S, Shim JS, Wu C
Cell death and differentiation 2025 Nov;32(11):2009-2021
Cell death and differentiation 2025 Nov;32(11):2009-2021
Systemic aldehyde storm induced by allyl alcohol exposure results in extensive hepatic ferroptosis in Aldh2∗2 knock-in mice.
Takami Y, Nakamura J, Katahira J, Maeda Y, Tanaka M, Kuwamura M, Okada T, Izawa T
Free radical biology & medicine 2025 Nov;239:177-188
Free radical biology & medicine 2025 Nov;239:177-188
Gambogic acid induces ferroptosis and suppresses colorectal cancer progression by modulating the m6A modification of p62.
Wang J, Deng J, Sun B, Qiao G, Yang J, Gao Z, Zhang Q, Dong M, Qu P, Wang Z
Cellular signalling 2025 Nov;135:112024
Cellular signalling 2025 Nov;135:112024
A novel biomimetic nanoplatform amplifies ferroptosis for specific cGAS-STING pathway activation to enhance hepatocellular carcinoma chemo-immunotherapy.
Peng H, Chang A, Zhang H, Xu X, Wang W, Zhang K, Yang J, Xie S, Peng X, Yin X, Qu C, Fu J, Ni J, Dong X
Journal of nanobiotechnology 2025 Nov 25;23(1):799
Journal of nanobiotechnology 2025 Nov 25;23(1):799
Elucidating a novel prognostic signature for bladder cancer by integrating hypoxia and lactate metabolism-related genes: comprehensive bioinformatics analyses and experimental evidence.
Zhao Y, Li P, Shen Z, Yao S, Zhang X, Zhang N, Chen J
BMC cancer 2025 Nov 21;25(1):1796
BMC cancer 2025 Nov 21;25(1):1796
CDC26 facilitates ferroptosis through SLC7A11 degradation and cell cycle arrest.
Lin J, Chen F, Tang H, Cai X, Huang M, Liang R, Kang R, Tang D, Liu J
Clinical and experimental medicine 2025 Nov 18;26(1):11
Clinical and experimental medicine 2025 Nov 18;26(1):11
B355252 Targets UCP2 to Rescue Intracerebral Hemorrhage-Induced Injury by Promoting Mitochondrial Fusion and Inhibiting Ferroptosis.
Han B, Ma C, Liu Y, Shi C, Guo J, Bai M, Duan M, Meng S, Liu J, He M
Molecular neurobiology 2025 Nov 15;63(1):43
Molecular neurobiology 2025 Nov 15;63(1):43
Synergetic contributions of Seneca Valley virus 3 C and 3D proteins to induction of ferroptosis for viral replication.
Song J, Yang J, Ma R, Li Z, Su J, Xie S, Cheng P
Cellular and molecular life sciences : CMLS 2025 Nov 14;82(1):406
Cellular and molecular life sciences : CMLS 2025 Nov 14;82(1):406
Targeting PIM1 by Bruceine D attenuates skin fibrosis via myofibroblast ferroptosis.
Wang J, Song Y, Tan X, Wang T, Shi Y, Xu X, Du J, Yu Z, Song B
Redox biology 2025 May;82:103619
Redox biology 2025 May;82:103619
Sirt1 overexpression inhibits chondrocyte ferroptosis via Ftl deacetylation to suppress the development of osteoarthritis.
Xiong X, Huang H, Wang N, Zhou K, Song X
Journal of bone and mineral metabolism 2025 May;43(3):203-215
Journal of bone and mineral metabolism 2025 May;43(3):203-215
Heterogeneity of fibroblasts from different anatomical sites in healthy human knee ligaments revealed by single-cell RNA sequencing.
Zhao H, Yao Y, Jiang F, Zhu X, Yu T, Xiao X
Genomics 2025 May;117(3):111040
Genomics 2025 May;117(3):111040
Astragenol alleviates neuroinflammation and improves Parkinson's symptoms through amino acid metabolism pathway and inhibition of ferroptosis.
Xiao S, Liu L, Qin X, Xu L, Chai Z, Li Z
Journal of ethnopharmacology 2025 May 28;348:119896
Journal of ethnopharmacology 2025 May 28;348:119896
The anti-Alzheimer's disease effects of ganoderic acid A by inhibiting ferroptosis-lipid peroxidation via activation of the NRF2/SLC7A11/GPX4 signaling pathway.
Lu Q, Shao N, Fang Z, Ouyang Z, Shen Y, Yang R, Liu H, Cai B, Wei T
Chemico-biological interactions 2025 May 1;412:111459
Chemico-biological interactions 2025 May 1;412:111459
The Lactate-Primed KAT8‒PCK2 Axis Exacerbates Hepatic Ferroptosis During Ischemia/Reperfusion Injury by Reprogramming OXSM-Dependent Mitochondrial Fatty Acid Synthesis.
Yuan J, Yang M, Wu Z, Wu J, Zheng K, Wang J, Zeng Q, Chen M, Lv T, Shi Y, Yang J, Yang J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(11):e2414141
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(11):e2414141
Gallic acid alleviates ferroptosis by negatively regulating APOC3 and improves nerve function deficit caused by traumatic brain injury.
Liu Y, Fu X, Li J, Guo J, Zhao Z, Zheng J
Scientific reports 2025 Mar 6;15(1):7815
Scientific reports 2025 Mar 6;15(1):7815
Monounsaturated fatty acids promote cancer radioresistance by inhibiting ferroptosis through ACSL3.
Cao Y, Li J, Chen Y, Wang Y, Liu Z, Huang L, Liu B, Feng Y, Yao S, Zhou L, Yin Y, Huang Z
Cell death & disease 2025 Mar 18;16(1):184
Cell death & disease 2025 Mar 18;16(1):184
Acid sphingomyelinase recruits palmitoylated CD36 to membrane rafts and enhances lipid uptake.
Ding M, Zhang Y, Xu X, Zhu Y, He H, Jiang T, Huang Y, Yu W, Ou H
The Journal of biological chemistry 2025 Jun;301(6):110213
The Journal of biological chemistry 2025 Jun;301(6):110213
MiR214-3p Ameliorates Diabetic Cardiomyopathy by Inhibiting Ferroptosis.
Chen P, Huang X, Wen W, Cao Y, Li W, Huang G, Huang Y, Hu Y, Ma T
Cardiovascular toxicology 2025 Jun;25(6):884-897
Cardiovascular toxicology 2025 Jun;25(6):884-897
Two novel SH3TC2 mutations predispose to Charcot-Marie-Tooth disease type 4C by mistargeting away from TFRC.
Li P, Wu Y, Deng Z, Samad A, Xi Y, Song J, Zhang Y, Li J, Zhou YA, Xiong Q, Wu C
Cellular signalling 2025 Jun;130:111669
Cellular signalling 2025 Jun;130:111669
ESRP1 exerts anti-tumor role by promoting ferroptosis in diffuse-type gastric cancer.
Xu K, Chen H, Zhu X, Li H, Liu X, Sang Y, Wang X, Cui X, Cai B, Shang L, Chong W, Li L
Journal of experimental & clinical cancer research : CR 2025 Jun 18;44(1):176
Journal of experimental & clinical cancer research : CR 2025 Jun 18;44(1):176
Fucoxanthin Ameliorates Carbon Tetrachloride-Induced Liver Fibrosis in Mice via Nrf2/HO-1/GPX4-Mediated Ferroptosis Pathway.
Liu Z, Ye J, Xi J, Li Q, Tang Y, Tian Y, Wang D, Yang Z, Ding Y
Food science & nutrition 2025 Jul;13(7):e70589
Food science & nutrition 2025 Jul;13(7):e70589
Heat shock protein B1-mediated ferroptosis regulates mitochondrial dysfunction in adipose tissue of ketotic dairy cows.
Fan Y, Ma L, Xu X, Fang X, Mauck J, Loor JJ, Sun X, Jia H, Xu C, Xu Q
Journal of dairy science 2025 Jul;108(7):7815-7836
Journal of dairy science 2025 Jul;108(7):7815-7836
Human β-casein-derived peptide BCCY-1 improved the intestinal barrier integrity by regulating the TLR4/eNOS/3-Nitrotyrosine axis.
Cai J, Yan X, Liu X, Yin X, Shi A, Ji C, Cao Y
Food chemistry 2025 Jan 15;463(Pt 1):140821
Food chemistry 2025 Jan 15;463(Pt 1):140821
Testosterone deficiency aggravates diet-induced non-alcoholic fatty liver disease by inducing hepatocyte ferroptosis via targeting BMAL1 in mice.
Fan Y, Ren Y, Deng L, Lv D, Chen J, Ling Y, Tu J, Xu X, Wang D, Cai Z
International immunopharmacology 2025 Jan 10;144:113641
International immunopharmacology 2025 Jan 10;144:113641
Bergenin inhibits ferritinophagy and ferroptosis in cisplatin-induced acute kidney injury by activating the p-GSK3β/Nrf2/PPARγ pathway.
Hu J, Zhang Y, Zhang Y, Shi N, Miu Y, Huang J, Miao M, Ci X
International immunopharmacology 2025 Feb 6;147:114004
International immunopharmacology 2025 Feb 6;147:114004
Hesperetin alleviates PM2.5-induced lung injury by inhibiting ferroptosis in an Nrf2-dependent manner.
Wang L, Tang Y, Hou T, Gao Y, Ci X, Peng L
International immunopharmacology 2025 Feb 20;148:114123
International immunopharmacology 2025 Feb 20;148:114123
Integrated network pharmacology, bioinformatics, and experiment analysis to decipher the molecular mechanism of Salidroside on Gastric cancer via targeting NCOA4-mediated ferritinophagy.
Fu Y, Huang G, Cai Y, Ren M, Cheng R, Chai Y, Wang Y, An Y, Yan T, Zhu L, Liu X
Chemico-biological interactions 2025 Feb 1;407:111368
Chemico-biological interactions 2025 Feb 1;407:111368
Crucial roles of asprosin in cisplatin-induced ferroptosis and acute kidney injury.
Zheng F, Lei JZ, Wang JX, Xu XY, Zhou B, Ge R, Dai M, Dong HK, Wu N, Li YH, Zhu GQ, Zhou YB
Free radical biology & medicine 2025 Feb 1;227:296-311
Free radical biology & medicine 2025 Feb 1;227:296-311
Norepinephrine Induces Sertoli Cell Ferroptosis via Receptors Desensitization Causing Stress-Related Male Reproductive Dysfunction.
Zhang L, Gao S, Xiong X, Liu X, Li R, Wang X, Han L, Xiao X, Wang X, Li W, Chang Y, Du Y, Yang J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(48):e04817
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(48):e04817
Exosomal miR-145-5p impairs neoadjuvant chemotherapy by suppressing TFRC-mediated macrophage iron uptake and driving M2 polarization in esophageal cancer.
Xu J, Lei D, Xu P, Wang Y, Li Z, Wu J, Feng W, Zhou J
Human cell 2025 Dec 24;39(1):27
Human cell 2025 Dec 24;39(1):27
Baicalein attenuates metabolic dysfunction-associated steatohepatitis by regulating macrophage ferroptosis through nuclear factor (erythroid-derived 2)-like 2 pathway.
Wang Y, Zhao Y, Zhao W, Chen H, Cao Z, Li H, Tang Y, Zhu X, Yao P
Free radical biology & medicine 2025 Dec 1;240:238-252
Free radical biology & medicine 2025 Dec 1;240:238-252
Activation of AKT via a dual mechanism enhances the susceptibility of melanoma cells to glucose deprivation.
Yang GX, Peng DL, Chen L, Qian Y, He L, Chen XY, Hong WB, Wu CM, Chen HZ
Cell death & disease 2025 Aug 7;16(1):595
Cell death & disease 2025 Aug 7;16(1):595
Hua Zheng San Ji Fang promotes ferroptosis through Keap1/Nrf2 pathway in hepatocellular carcinoma cells.
Su B, Wang S, Xiong Z, Liu T, Leng Y, Deng H, Liu L, Sui X
Journal of ethnopharmacology 2025 Aug 29;352:120165
Journal of ethnopharmacology 2025 Aug 29;352:120165
Role of ferroptosis mediated by abnormal membrane structure in DEHP-induced reproductive injury.
Deng W, Zhao J, Wang X, Li D, Wang M, Zheng X, Wang R, Guo Q, Zhao P, Yan H, Shen L, Long C, Wei G, Wu S
Free radical biology & medicine 2025 Aug 1;235:150-161
Free radical biology & medicine 2025 Aug 1;235:150-161
Targeting GPX4 alleviates ferroptosis and retards abdominal aortic aneurysm formation.
Shi Y, Zhao Y, Sun SJ, Lan XT, Wu WB, Zhang Z, Chen YX, Yan YY, Xu YP, Li DJ, Fu H, Shen FM
Biochemical pharmacology 2025 Apr;234:116800
Biochemical pharmacology 2025 Apr;234:116800
TAZ/NRF2 positive feedback loop contributes to proliferation in bladder cancer through antagonistic ferroptosis.
Song Z, Gui S, Rao X, Zhang G, Cheng Y, Zeng T
Cell death discovery 2025 Apr 29;11(1):208
Cell death discovery 2025 Apr 29;11(1):208
Artesunate induces ferroptosis in osteosarcoma through NCOA4-mediated ferritinophagy.
Huang R, Xu R, Shi J, Yang Z, Zheng J, Wei D
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Apr 15;39(7):e70488
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Apr 15;39(7):e70488
Triptolide Attenuates Renal Slit Diagram to Tight Junction Transition in Diabetic Kidney Disease by Regulating Nrf2-Ferroptosis Pathway.
Wang HQ, Wu HX, Shi WQ, Yang Y, Lin M, Wang K, Bian CC, An XF, Wang T, Yan M
The American journal of Chinese medicine 2024;52(7):2161-2185
The American journal of Chinese medicine 2024;52(7):2161-2185
Propofol and Dexmedetomidine Ameliorate Endotoxemia-Associated Encephalopathy via Inhibiting Ferroptosis.
Zhou Y, Yang Y, Yi L, Pan M, Tang W, Duan H
Drug design, development and therapy 2024;18:1349-1368
Drug design, development and therapy 2024;18:1349-1368
Progressive iron overload in middle-aged mice impairs olfactory function, triggers lipid oxidation and induces apoptosis.
Deng L, Luo Q, Liu Y, Wang Y, Xiong Z, Wang H, Zhao L, Jia L, Shi R, Huang C, Chen Z
Frontiers in pharmacology 2024;15:1506944
Frontiers in pharmacology 2024;15:1506944
Daphnetin induces ferroptosis in ovarian cancer by inhibiting NAD(P)H:Quinone oxidoreductase 1 (NQO1).
Ma N, Zhang M, Hu J, Wei Z, Zhang S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155876
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155876
Deferoxamine alleviates chondrocyte senescence and osteoarthritis progression by maintaining iron homeostasis.
Guo Z, Lin Y, Liu H, Guo J, Hou L, Zhang X, Xu J, Ruan Z, Li M, Sun K, Guo F
International immunopharmacology 2024 Sep 30;139:112619
International immunopharmacology 2024 Sep 30;139:112619
Corilagin alleviates ferroptosis in diabetic retinopathy by activating the Nrf2 signaling pathway.
Shi W, Dong Y, Liu S, Li F, Zhu C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Oct;179:117409
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Oct;179:117409
Proteomics reveals the pharmacological mechanism of flavonoids from Astragali Complanati Semen in preventing chronic liver injury.
Chen L, Kong X, Zhou R, Hu J, Zhou R, Song Z, Tang Z, Wang M
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Oct;133:155910
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Oct;133:155910
Intra-articular injection of platinum nanozyme-loaded silk fibroin/pullulan hydrogels relieves osteoarthritis through ROS scavenging and ferroptosis suppression.
Feng J, Deng X, Hao P, Zhu Z, Li T, Yuan X, Hu J, Wang Y
International journal of biological macromolecules 2024 Nov;280(Pt 2):135863
International journal of biological macromolecules 2024 Nov;280(Pt 2):135863
Novel biallelic variants in IREB2 cause an early-onset neurodegenerative disorder in a Chinese pedigree.
Guo Z, Huo D, Shao Y, Yang W, Wang J, Zhang Y, Xiao H, Hao B, Liao S
Orphanet journal of rare diseases 2024 Nov 25;19(1):435
Orphanet journal of rare diseases 2024 Nov 25;19(1):435
Platycodin D ameliorates polycystic ovary syndrome-induced ovarian damage by upregulating CD44 to attenuate ferroptosis.
Ji R, Wang S, Chen X, Yang Z, Zhang Z, Bao S, Xiao Z, Zhang Y, Yin T, Yang J
Free radical biology & medicine 2024 Nov 1;224:707-722
Free radical biology & medicine 2024 Nov 1;224:707-722
Dampening of ISGylation of RIG-I by ADAP regulates type I interferon response of macrophages to RNA virus infection.
Wang Y, Feng H, Li X, Ruan Y, Guo Y, Cui X, Zhang P, Li Y, Wang X, Wang X, Wei L, Yi Y, Zhang L, Yang X, Liu H
PLoS pathogens 2024 May;20(5):e1012230
PLoS pathogens 2024 May;20(5):e1012230
Injectable, anti-collapse, adhesive, plastic and bioactive bone graft substitute promotes bone regeneration by moderating oxidative stress in osteoporotic bone defect.
Huang L, Zhang S, Bian M, Xiang X, Xiao L, Wang J, Lu S, Chen W, Zhang C, Mo G, Jiang L, Li Y, Zhang J
Acta biomaterialia 2024 May;180:82-103
Acta biomaterialia 2024 May;180:82-103
Kinase PIM1 governs ferroptosis to reduce retinal microvascular endothelial cell dysfunction triggered by high glucose.
Xie HB, Guo JH, Yang MM, Wang JT
In vitro cellular & developmental biology. Animal 2024 Mar;60(3):278-286
In vitro cellular & developmental biology. Animal 2024 Mar;60(3):278-286
Glioma-targeted oxaliplatin/ferritin clathrate reversing the immunosuppressive microenvironment through hijacking Fe(2+) and boosting Fenton reaction.
Li X, Cheng Y, Yang Z, Ji Q, Huan M, Ye W, Liu M, Zhang B, Liu D, Zhou S
Journal of nanobiotechnology 2024 Mar 5;22(1):93
Journal of nanobiotechnology 2024 Mar 5;22(1):93
Nicorandil Regulates Ferroptosis and Mitigates Septic Cardiomyopathy via TLR4/SLC7A11 Signaling Pathway.
Lu JS, Wang JH, Han K, Li N
Inflammation 2024 Jun;47(3):975-988
Inflammation 2024 Jun;47(3):975-988
Anti-tumor immunotherapy using engineered bacterial outer membrane vesicles fused to lysosome-targeting chimeras mediated by transferrin receptor.
Su LY, Tian Y, Zheng Q, Cao Y, Yao M, Wang S, Xu W, Xi C, Clocchiatti A, Nie G, Zhou H
Cell chemical biology 2024 Jun 20;31(6):1219-1230.e5
Cell chemical biology 2024 Jun 20;31(6):1219-1230.e5
Mitoferrin2 is a synthetic lethal target for chromosome 8p deleted cancers.
Krieg S, Rohde T, Rausch T, Butthof L, Wendler-Link L, Eckert C, Breuhahn K, Galy B, Korbel J, Billmann M, Breinig M, Tschaharganeh DF
Genome medicine 2024 Jun 17;16(1):83
Genome medicine 2024 Jun 17;16(1):83
Neurotoxicity of manganese via ferroptosis induced by redox imbalance and iron overload.
Wang C, Zhao H, Liu Y, Qu M, Lv S, He G, Liang H, Chen K, Yang L, He Y, Ou C
Ecotoxicology and environmental safety 2024 Jun 15;278:116404
Ecotoxicology and environmental safety 2024 Jun 15;278:116404
Ciprofloxacin is a novel anti-ferroptotic antibiotic.
Chen F, Tang H, Lin J, Kang R, Tang D, Liu J
Heliyon 2024 Jun 15;10(11):e32571
Heliyon 2024 Jun 15;10(11):e32571
Salvia miltiorrhiza Bge. processed with porcine cardiac blood inhibited GLRX5-mediated ferroptosis alleviating cerebral ischemia-reperfusion injury.
Zhou S, Wang Z, Wang T, Peng C, Zhang J, Liu C, Xu J, Zhang Y, Zhang L, Luo L, Yan X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155622
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155622
Ambra1 in exosomes secreted by HK-2 cells damaged by supersaturated oxalate induce mitophagy and autophagy-ferroptosis in normal HK-2 cells to participate in the occurrence of kidney stones.
Su X, Song C, He Z, Song Q, Meng L, Dong C, Zhou J, Ke H, Xiong Y, Liu J, Liao W, Yang S
Biochimica et biophysica acta. Molecular cell research 2024 Jan;1871(1):119604
Biochimica et biophysica acta. Molecular cell research 2024 Jan;1871(1):119604
Transient receptor potential channel TRPM4 favors oxidized low-density lipoprotein-induced coronary endothelial cell dysfunction via a mechanism involving ferroptosis.
Ye F, Liu D, Zhang J
Tissue & cell 2024 Feb;86:102290
Tissue & cell 2024 Feb;86:102290
Heterogeneous ferroptosis susceptibility of macrophages caused by focal iron overload exacerbates rheumatoid arthritis.
Liu Y, Luo X, Chen Y, Dang J, Zeng D, Guo X, Weng W, Zhao J, Shi X, Chen J, Dong B, Zhong S, Ren J, Li Y, Wang J, Zhang J, Sun J, Xu H, Lu Y, Brand D, Zheng SG, Pan Y
Redox biology 2024 Feb;69:103008
Redox biology 2024 Feb;69:103008
The clustering status of detached gastric cancer cells inhibits anoikis-induced ferroptosis to promote metastatic colonization.
Sun J, Li J, Pantopoulos K, Liu Y, He Y, Kang W, Ye X
Cancer cell international 2024 Feb 18;24(1):77
Cancer cell international 2024 Feb 18;24(1):77
Pro-ferroptotic signaling promotes arterial aging via vascular smooth muscle cell senescence.
Sun DY, Wu WB, Wu JJ, Shi Y, Xu JJ, Ouyang SX, Chi C, Shi Y, Ji QX, Miao JH, Fu JT, Tong J, Zhang PP, Zhang JB, Li ZY, Qu LF, Shen FM, Li DJ, Wang P
Nature communications 2024 Feb 16;15(1):1429
Nature communications 2024 Feb 16;15(1):1429
Inhibition of CDGSH iron‑sulfur domain 2 exhibits tumor-suppressing effects on diffuse large B-cell lymphoma (DLBCL) by inducing ferroptosis through the regulation of the NRF2/SLC7A11/GPX4 pathway.
Zhang J, Wang T, Zhang H, Li N, Liu B, Fang L
Toxicology and applied pharmacology 2024 Dec;493:117148
Toxicology and applied pharmacology 2024 Dec;493:117148
Copper as the driver of the lncRNA-TCONS-6251/miR-novel-100/TC2N axis: Unraveling ferroptosis in duck kidney.
Peng J, Dai X, Zhang T, Hu G, Cao H, Guo X, Fan H, Chen J, Tang W, Yang F
International journal of biological macromolecules 2024 Dec;282(Pt 2):136797
International journal of biological macromolecules 2024 Dec;282(Pt 2):136797
Network pharmacology, molecular docking and experimental study on the mechanism of Curcumin's anti-ferroptosis in melanocytes.
Liu LY, He SJ, Luo J, Huang JK, Yuan JX, Yuan CJ, Zhang JL
Biochemical and biophysical research communications 2024 Dec 3;736:150871
Biochemical and biophysical research communications 2024 Dec 3;736:150871
Melatonin protects against particulate matter-induced ovarian dysfunction by activating the Nrf2 signaling pathway to alleviate ferroptosis.
Zhang X, Man X, Zhang Q, Zhu L, Chen L, Zhu C, Ci X, Yu X
Life sciences 2024 Dec 15;359:123200
Life sciences 2024 Dec 15;359:123200
Chronic microcystin-leucine-arginine exposure induces osteoporosis by breaking the balance of osteoblasts and osteoclasts.
Pan C, Wang K, Hong R, Wang X, Zhang Y, Fan Z, Shi Y, Liu T, Chen H
Environmental research 2024 Dec 15;263(Pt 2):120098
Environmental research 2024 Dec 15;263(Pt 2):120098
Effects on Iron Metabolism and System Xc- /GPX4 Pathway from Hydroquinone Suggest Ferroptosis of Jurkat Cells.
Liu N, Liu G, Li Q, Hu Y, Wang H
Toxics 2024 Aug 31;12(9)
Toxics 2024 Aug 31;12(9)
CCT3/ACTN4/TFRC axis protects hepatocellular carcinoma cells from ferroptosis by inhibiting iron endocytosis.
Zhu H, Liu Q, Meng Q, Zhang L, Ju S, Lang J, Zhu D, Chen Y, Aishan N, Ouyang X, Zhang S, Jin L, Xiao L, Wang L, Li L, Ji F
Journal of experimental & clinical cancer research : CR 2024 Aug 29;43(1):245
Journal of experimental & clinical cancer research : CR 2024 Aug 29;43(1):245
Bulk RNA-sequencing, single-cell RNA-sequencing analysis, and experimental validation reveal iron metabolism-related genes CISD2 and CYP17A1 are potential diagnostic markers for recurrent pregnancy loss.
He YB, Han L, Wang C, Fang J, Shang Y, Cai HL, Zhou Q, Zhang ZZ, Chen SL, Li JY, Liu YL
Gene 2024 Apr 5;901:148168
Gene 2024 Apr 5;901:148168
Targeted delivery of MerTK protein via cell membrane engineered nanoparticle enhances efferocytosis and attenuates atherosclerosis in diabetic ApoE(-/-) Mice.
Qiu S, Liu J, Chen J, Li Y, Bu T, Li Z, Zhang L, Sun W, Zhou T, Hu W, Yang G, Yuan L, Duan Y, Xing C
Journal of nanobiotechnology 2024 Apr 13;22(1):178
Journal of nanobiotechnology 2024 Apr 13;22(1):178
Targeted elimination of senescent cells by engineered extracellular vesicles attenuates atherosclerosis in ApoE(-/-) mice with minimal side effects.
Zhang L, Wang C, Hu W, Bu T, Sun W, Zhou T, Qiu S, Wei M, Xing H, Li Z, Yang G, Yuan L
Theranostics 2023;13(14):5114-5129
Theranostics 2023;13(14):5114-5129
Overexpressed transferrin receptor implied poor prognosis and relapse in gastrointestinal stromal tumors.
Zhuang C, Li X, Yang L, Ma X, Shen Y, Huang C, Pan T, Cui J, Ni B, Wang M
Frontiers in oncology 2023;13:1151687
Frontiers in oncology 2023;13:1151687
Bioengineered "Molecular Glue"-Mediated Tumor-Specific Cascade Nanoreactors with Self-Destruction Ability for Enhanced Precise Starvation/Chemosynergistic Tumor Therapy.
Zhang Q, Xuan Q, Wang C, Shi C, Wang X, Ma T, Zhang W, Li H, Wang P, Chen C
ACS applied materials & interfaces 2023 Sep 6;15(35):41271-41286
ACS applied materials & interfaces 2023 Sep 6;15(35):41271-41286
Exogenous spermidine alleviates diabetic cardiomyopathy via suppressing reactive oxygen species, endoplasmic reticulum stress, and Pannexin-1-mediated ferroptosis.
Sun J, Xu J, Liu Y, Lin Y, Wang F, Han Y, Zhang S, Gao X, Xu C, Yuan H
Biomolecules & biomedicine 2023 Sep 4;23(5):825-837
Biomolecules & biomedicine 2023 Sep 4;23(5):825-837
Knockdown of ANXA10 induces ferroptosis by inhibiting autophagy-mediated TFRC degradation in colorectal cancer.
Wang X, Zhou Y, Ning L, Chen J, Chen H, Li X
Cell death & disease 2023 Sep 4;14(9):588
Cell death & disease 2023 Sep 4;14(9):588
Yttrium chloride induces ferroptosis in cardiomyocytes via iron accumulation and triggers cardiac lipid peroxidation and inflammation that cause heart adverse events in mice.
Xiong L, Huang J, Wu C, Yuan Q, Wang S, Zhu L, Li Z, Sun Z, Fang Y, Li W, Hu G
Ecotoxicology and environmental safety 2023 Sep 15;263:115279
Ecotoxicology and environmental safety 2023 Sep 15;263:115279
Activation of Nrf2 signalling pathway by tectoridin protects against ferroptosis in particulate matter-induced lung injury.
Dong T, Fan X, Zheng N, Yan K, Hou T, Peng L, Ci X
British journal of pharmacology 2023 Oct;180(19):2532-2549
British journal of pharmacology 2023 Oct;180(19):2532-2549
Exogenous H(2)S initiating Nrf2/GPx4/GSH pathway through promoting Syvn1-Keap1 interaction in diabetic hearts.
Wang M, Tang J, Zhang S, Pang K, Zhao Y, Liu N, Huang J, Kang J, Dong S, Li H, Tian Z, Duan B, Lu F, Zhang W
Cell death discovery 2023 Oct 24;9(1):394
Cell death discovery 2023 Oct 24;9(1):394
Heme-deficient primitive red blood cells induce HSPC ferroptosis by altering iron homeostasis during zebrafish embryogenesis.
Lv P, Liu F
Development (Cambridge, England) 2023 Oct 15;150(20)
Development (Cambridge, England) 2023 Oct 15;150(20)
Curcumin alleviates AFB1-induced nephrotoxicity in ducks: regulating mitochondrial oxidative stress, ferritinophagy, and ferroptosis.
Liu H, He Y, Gao X, Li T, Qiao B, Tang L, Lan J, Su Q, Ruan Z, Tang Z, Hu L
Mycotoxin research 2023 Nov;39(4):437-451
Mycotoxin research 2023 Nov;39(4):437-451
Hydrogen sulfide ameliorates endothelial dysfunction in aging arteries by regulating ferroptosis.
Miao Y, Zhang S, Liang Z, Wang Y, Tian D, Jin S, Guo Q, Xue H, Teng X, Xiao L, Wu Y
Nitric oxide : biology and chemistry 2023 Nov 1;140-141:77-90
Nitric oxide : biology and chemistry 2023 Nov 1;140-141:77-90
Loureirin C inhibits ferroptosis after cerebral ischemia reperfusion through regulation of the Nrf2 pathway in mice.
Liu Y, Mi Y, Wang Y, Meng Q, Xu L, Liu Y, Zhou D, Wang Y, Liang D, Li W, Li N, Hou Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 May;113:154729
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 May;113:154729
Artesunate, a new antimalarial clinical drug, exhibits potent anti-AML activity by targeting the ROS/Bim and TFRC/Fe(2+) pathways.
Liu Y, Li H, Luo Z, Yu Y, Yang J, Zhang M, Law BYK, Huang Z, Li W
British journal of pharmacology 2023 Mar;180(6):701-720
British journal of pharmacology 2023 Mar;180(6):701-720
Dihydroartemisinin-induced ferroptosis in acute myeloid leukemia: links to iron metabolism and metallothionein.
Grignano E, Cantero-Aguilar L, Tuerdi Z, Chabane T, Vazquez R, Johnson N, Zerbit J, Decroocq J, Birsen R, Fontenay M, Kosmider O, Chapuis N, Bouscary D
Cell death discovery 2023 Mar 17;9(1):97
Cell death discovery 2023 Mar 17;9(1):97
Thorium(IV) triggers ferroptosis through disrupting iron homeostasis and heme metabolism in the liver following oral ingestion.
Ma M, Wang R, Xu M
Journal of hazardous materials 2023 Jun 15;452:131217
Journal of hazardous materials 2023 Jun 15;452:131217
Palmitic acid-induced ferroptosis via CD36 activates ER stress to break calcium-iron balance in colon cancer cells.
Kuang H, Sun X, Liu Y, Tang M, Wei Y, Shi Y, Li R, Xiao G, Kang J, Wang F, Peng J, Xu H, Zhou F
The FEBS journal 2023 Jul;290(14):3664-3687
The FEBS journal 2023 Jul;290(14):3664-3687
ATM orchestrates ferritinophagy and ferroptosis by phosphorylating NCOA4.
Wu H, Liu Q, Shan X, Gao W, Chen Q
Autophagy 2023 Jul;19(7):2062-2077
Autophagy 2023 Jul;19(7):2062-2077
Hydrogen sulfide alleviates mitochondrial damage and ferroptosis by regulating OPA3-NFS1 axis in doxorubicin-induced cardiotoxicity.
Wang Y, Ying X, Wang Y, Zou Z, Yuan A, Xiao Z, Geng N, Qiao Z, Li W, Lu X, Pu J
Cellular signalling 2023 Jul;107:110655
Cellular signalling 2023 Jul;107:110655
Fucoxanthin triggers ferroptosis in glioblastoma cells by stabilizing the transferrin receptor.
Zhu Q, Zhou Y, Wang H, Cao T, Wang X, Liu R, Wu H, Lin B
Medical oncology (Northwood, London, England) 2023 Jul 8;40(8):230
Medical oncology (Northwood, London, England) 2023 Jul 8;40(8):230
Melatonin inhibits ferroptosis and delays age-related cataract by regulating SIRT6/p-Nrf2/GPX4 and SIRT6/NCOA4/FTH1 pathways.
Mi Y, Wei C, Sun L, Liu H, Zhang J, Luo J, Yu X, He J, Ge H, Liu P
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jan;157:114048
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jan;157:114048
Sphingosine 1-phosphate alleviates radiation-induced ferroptosis in ovarian granulosa cells by upregulating glutathione peroxidase 4.
Zhao J, Tang M, Tang H, Wang M, Guan H, Tang L, Zhang H
Reproductive toxicology (Elmsford, N.Y.) 2023 Jan;115:49-55
Reproductive toxicology (Elmsford, N.Y.) 2023 Jan;115:49-55
ATP6V0D1 promotes alkaliptosis by blocking STAT3-mediated lysosomal pH homeostasis.
Chen F, Zhu S, Kang R, Tang D, Liu J
Cell reports 2023 Jan 31;42(1):111911
Cell reports 2023 Jan 31;42(1):111911
Ferroptotic stress facilitates smooth muscle cell dedifferentiation in arterial remodelling by disrupting mitochondrial homeostasis.
Ji QX, Zeng FY, Zhou J, Wu WB, Wang XJ, Zhang Z, Zhang GY, Tong J, Sun DY, Zhang JB, Cao WX, Shen FM, Lu JJ, Li DJ, Wang P
Cell death and differentiation 2023 Feb;30(2):457-474
Cell death and differentiation 2023 Feb;30(2):457-474
Ferroptosis is involved in PM2.5-induced acute nasal epithelial injury via AMPK-mediated autophagy.
Gu W, Hou T, Zhou H, Zhu L, Zhu W, Wang Y
International immunopharmacology 2023 Feb;115:109658
International immunopharmacology 2023 Feb;115:109658
Ferroptosis is involved in corpus cavernosum smooth muscle cells impairment in diabetes mellitus-induced erectile dysfunction.
Xu W, Sun T, Wang J, Wang T, Wang S, Liu J, Liu K, Li H
Andrology 2023 Feb;11(2):332-343
Andrology 2023 Feb;11(2):332-343
Transferrin Receptor is Associated with Sensitivity to Ferroptosis Inducers in Hepatocellular Carcinoma.
Hiromatsu M, Toshida K, Itoh S, Harada N, Kohashi K, Oda Y, Yoshizumi T
Annals of surgical oncology 2023 Dec;30(13):8675-8689
Annals of surgical oncology 2023 Dec;30(13):8675-8689
Knockdown of SETD2 promotes erastin-induced ferroptosis in ccRCC.
Xue W, Jian W, Meng Y, Wang T, Cai L, Yu Y, Yu Y, Xia Z, Zhang C
Cell death & disease 2023 Aug 21;14(8):539
Cell death & disease 2023 Aug 21;14(8):539
Hormone replacement therapy for postmenopausal atherosclerosis is offset by late age iron deposition.
Xu T, Cai J, Wang L, Xu L, Zhao H, Wang F, Meyron-Holtz EG, Missirlis F, Qiao T, Li K
eLife 2023 Aug 10;12
eLife 2023 Aug 10;12
LncRNA modulates Hippo-YAP signaling to reprogram iron metabolism.
He XY, Fan X, Qu L, Wang X, Jiang L, Sang LJ, Shi CY, Lin S, Yang JC, Yang ZZ, Lei K, Li JH, Ju HQ, Yan Q, Liu J, Wang F, Shao J, Xiong Y, Wang W, Lin A
Nature communications 2023 Apr 20;14(1):2253
Nature communications 2023 Apr 20;14(1):2253
EPC-exosomal miR-26a-5p improves airway remodeling in COPD by inhibiting ferroptosis of bronchial epithelial cells via PTGS2/PGE2 signaling pathway.
Liu C, Lu J, Yuan T, Xie L, Zhang L
Scientific reports 2023 Apr 14;13(1):6126
Scientific reports 2023 Apr 14;13(1):6126
Cyclosporine A-loaded apoferritin alleviates myocardial ischemia-reperfusion injury by simultaneously blocking ferroptosis and apoptosis of cardiomyocytes.
Qian W, Liu D, Han Y, Liu M, Liu B, Ji Q, Zhang B, Mei Q, Zhou S, Cheng Y
Acta biomaterialia 2023 Apr 1;160:265-280
Acta biomaterialia 2023 Apr 1;160:265-280
Single-cell transcriptomics uncover the key ferroptosis regulators contribute to cancer progression in head and neck squamous cell carcinoma.
Liu F, Tang L, Li Q, Chen L, Pan Y, Yin Z, He J, Tian J
Frontiers in molecular biosciences 2022;9:962742
Frontiers in molecular biosciences 2022;9:962742
Role of TFRC as a Novel Prognostic Biomarker and in Immunotherapy for Pancreatic Carcinoma.
Yang C, Li J, Guo Y, Gan D, Zhang C, Wang R, Hua L, Zhu L, Ma P, Shi J, Li S, Su H
Frontiers in molecular biosciences 2022;9:756895
Frontiers in molecular biosciences 2022;9:756895
Exosomes derived from pericardial adipose tissues attenuate cardiac remodeling following myocardial infarction by Adipsin-regulated iron homeostasis.
Man W, Song X, Xiong Z, Gu J, Lin J, Gu X, Yu D, Li C, Jiang M, Zhang X, Yang Z, Cao Y, Zhang Y, Shu X, Wu D, Wang H, Ji G, Sun D
Frontiers in cardiovascular medicine 2022;9:1003282
Frontiers in cardiovascular medicine 2022;9:1003282
Hepatic TGFβr1 Deficiency Attenuates Lipopolysaccharide/D-Galactosamine-Induced Acute Liver Failure Through Inhibiting GSK3β-Nrf2-Mediated Hepatocyte Apoptosis and Ferroptosis.
Huang S, Wang Y, Xie S, Lai Y, Mo C, Zeng T, Kuang S, Deng G, Zhou C, Chen Y, Huang S, Gao L, Lv Z
Cellular and molecular gastroenterology and hepatology 2022;13(6):1649-1672
Cellular and molecular gastroenterology and hepatology 2022;13(6):1649-1672
Dexmedetomidine prevents hemorrhagic brain injury by reducing damage induced by ferroptosis in mice.
Liu MJ, Zhao XC, Gong HS, You YQ, Li JY
Neuroscience letters 2022 Sep 25;788:136842
Neuroscience letters 2022 Sep 25;788:136842
Phospholipid peroxidation-driven modification of chondrogenic transcription factor mediates alkoxyl radicals-induced impairment of embryonic bone development.
Niu J, Wan X, Yu GY, Jiang S, Yi RN, Wu YP, Ouyang SH, Liang L, Kurihara H, Sun WY, Zhu XF, Zhang RH, Cao YF, He JB, Duan WJ, Li YF, He RR
Redox biology 2022 Oct;56:102437
Redox biology 2022 Oct;56:102437
L-Citrulline Supplementation Restrains Ferritinophagy-Mediated Ferroptosis to Alleviate Iron Overload-Induced Thymus Oxidative Damage and Immune Dysfunction.
Ba T, Zhao D, Chen Y, Zeng C, Zhang C, Niu S, Dai H
Nutrients 2022 Oct 28;14(21)
Nutrients 2022 Oct 28;14(21)
Per1/Per2 knockout Affects Spleen Immune Function in Elderly Mice via Inducing Spleen Lymphocyte Ferroptosis.
He R, Zhang S, Yu J, Yu X, Wang J, Qiu Y, Zhou W, Wang F, Ren F, Liu Z
International journal of molecular sciences 2022 Oct 26;23(21)
International journal of molecular sciences 2022 Oct 26;23(21)
Farrerol alleviates collagenase-induced tendinopathy by inhibiting ferroptosis in rats.
Wu Y, Qian J, Li K, Li W, Yin W, Jiang H
Journal of cellular and molecular medicine 2022 Jun;26(12):3483-3494
Journal of cellular and molecular medicine 2022 Jun;26(12):3483-3494
Spatial region-resolved proteome map reveals mechanism of COVID-19-associated heart injury.
Leng L, Ma J, Zhang PP, Xu SC, Li X, Jin Y, Cai J, Tang R, Zhao L, He ZC, Li MS, Zhang H, Zhou LR, Wu ZH, Li TR, Zhu YP, Wang YJ, Wu HB, Ping YF, Yao XH, Zhu CH, Guo HT, Tan LY, Liang ZY, Bian XW, Zhang SY
Cell reports 2022 Jun 14;39(11):110955
Cell reports 2022 Jun 14;39(11):110955
ENO1 suppresses cancer cell ferroptosis by degrading the mRNA of iron regulatory protein 1.
Zhang T, Sun L, Hao Y, Suo C, Shen S, Wei H, Ma W, Zhang P, Wang T, Gu X, Li ST, Chen Z, Yan R, Zhang Y, Cai Y, Zhou R, Jia W, Huang F, Gao P, Zhang H
Nature cancer 2022 Jan;3(1):75-89
Nature cancer 2022 Jan;3(1):75-89
3D two-photon brain imaging reveals dihydroartemisinin exerts antiepileptic effects by modulating iron homeostasis.
Shao C, Liu Y, Chen Z, Qin Y, Wang X, Wang X, Yan C, Zhu HL, Zhao J, Qian Y
Cell chemical biology 2022 Jan 20;29(1):43-56.e12
Cell chemical biology 2022 Jan 20;29(1):43-56.e12
Lipid kinases VPS34 and PIKfyve coordinate a phosphoinositide cascade to regulate retriever-mediated recycling on endosomes.
Giridharan SSP, Luo G, Rivero-Rios P, Steinfeld N, Tronchere H, Singla A, Burstein E, Billadeau DD, Sutton MA, Weisman LS
eLife 2022 Jan 18;11
eLife 2022 Jan 18;11
Aging is associated with increased brain iron through cortex-derived hepcidin expression.
Sato T, Shapiro JS, Chang HC, Miller RA, Ardehali H
eLife 2022 Jan 11;11
eLife 2022 Jan 11;11
Iron transport across the human placenta is regulated by hepcidin.
McDonald EA, Gundogan F, Olveda RM, Bartnikas TB, Kurtis JD, Friedman JF
Pediatric research 2022 Aug;92(2):396-402
Pediatric research 2022 Aug;92(2):396-402
Leonurine alleviates ferroptosis in cisplatin-induced acute kidney injury by activating the Nrf2 signalling pathway.
Hu J, Gu W, Ma N, Fan X, Ci X
British journal of pharmacology 2022 Aug;179(15):3991-4009
British journal of pharmacology 2022 Aug;179(15):3991-4009
The role of ferritin and iron dextran in exacerbating preeclampsia in an L-NAME-treated rat model.
Zhu X, Jiang R, Ying X, Li Z, Jiang P
Annals of translational medicine 2022 Aug;10(16):889
Annals of translational medicine 2022 Aug;10(16):889
The Ferroptosis-NLRP1 Inflammasome: The Vicious Cycle of an Adverse Pregnancy.
Meihe L, Shan G, Minchao K, Xiaoling W, Peng A, Xili W, Jin Z, Huimin D
Frontiers in cell and developmental biology 2021;9:707959
Frontiers in cell and developmental biology 2021;9:707959
WDR45 Mutation Impairs the Autophagic Degradation of Transferrin Receptor and Promotes Ferroptosis.
Xiong Q, Li X, Li W, Chen G, Xiao H, Li P, Wu C
Frontiers in molecular biosciences 2021;8:645831
Frontiers in molecular biosciences 2021;8:645831
Ferroportin-Dependent Iron Homeostasis Protects against Oxidative Stress-Induced Nucleus Pulposus Cell Ferroptosis and Ameliorates Intervertebral Disc Degeneration In Vivo.
Lu S, Song Y, Luo R, Li S, Li G, Wang K, Liao Z, Wang B, Ke W, Xiang Q, Chen C, Wu X, Zhang Y, Ling L, Yang C
Oxidative medicine and cellular longevity 2021;2021:6670497
Oxidative medicine and cellular longevity 2021;2021:6670497
Oxalate Activates Autophagy to Induce Ferroptosis of Renal Tubular Epithelial Cells and Participates in the Formation of Kidney Stones.
Song Q, Liao W, Chen X, He Z, Li D, Li B, Liu J, Liu L, Xiong Y, Song C, Yang S
Oxidative medicine and cellular longevity 2021;2021:6630343
Oxidative medicine and cellular longevity 2021;2021:6630343
The blood-brain barrier studied in vitro across species.
Thomsen MS, Humle N, Hede E, Moos T, Burkhart A, Thomsen LB
PloS one 2021;16(3):e0236770
PloS one 2021;16(3):e0236770
Dipetidyl peptidase-4 and transferrin receptor serve as prognostic biomarkers for acute myeloid leukemia.
Wei J, Nai GY, Dai Y, Huang XJ, Xiong MY, Yao XY, Huang ZN, Li SN, Zhou WJ, Huang Y, Cheng P, Deng DH
Annals of translational medicine 2021 Sep;9(17):1381
Annals of translational medicine 2021 Sep;9(17):1381
The metabolite α-KG induces GSDMC-dependent pyroptosis through death receptor 6-activated caspase-8.
Zhang JY, Zhou B, Sun RY, Ai YL, Cheng K, Li FN, Wang BR, Liu FJ, Jiang ZH, Wang WJ, Zhou D, Chen HZ, Wu Q
Cell research 2021 Sep;31(9):980-997
Cell research 2021 Sep;31(9):980-997
Chitosan-based nanoparticle co-delivery of docetaxel and curcumin ameliorates anti-tumor chemoimmunotherapy in lung cancer.
Zhu X, Yu Z, Feng L, Deng L, Fang Z, Liu Z, Li Y, Wu X, Qin L, Guo R, Zheng Y
Carbohydrate polymers 2021 Sep 15;268:118237
Carbohydrate polymers 2021 Sep 15;268:118237
Atractylodin may induce ferroptosis of human hepatocellular carcinoma cells.
He Y, Fang D, Liang T, Pang H, Nong Y, Tang L, Yang Z, Lu C, Han X, Zhao S, Mo S, Meng Y, Han C, Peng T
Annals of translational medicine 2021 Oct;9(20):1535
Annals of translational medicine 2021 Oct;9(20):1535
Seizure-mediated iron accumulation and dysregulated iron metabolism after status epilepticus and in temporal lobe epilepsy.
Zimmer TS, David B, Broekaart DWM, Schidlowski M, Ruffolo G, Korotkov A, van der Wel NN, van Rijen PC, Mühlebner A, van Hecke W, Baayen JC, Idema S, François L, van Eyll J, Dedeurwaerdere S, Kessels HW, Surges R, Rüber T, Gorter JA, Mills JD, van Vliet EA, Aronica E
Acta neuropathologica 2021 Oct;142(4):729-759
Acta neuropathologica 2021 Oct;142(4):729-759
LPS-induced macrophage HMGB1-loaded extracellular vesicles trigger hepatocyte pyroptosis by activating the NLRP3 inflammasome.
Wang G, Jin S, Huang W, Li Y, Wang J, Ling X, Huang Y, Hu Y, Li C, Meng Y, Li X
Cell death discovery 2021 Nov 6;7(1):337
Cell death discovery 2021 Nov 6;7(1):337
Nuciferine protects against folic acid-induced acute kidney injury by inhibiting ferroptosis.
Li D, Liu B, Fan Y, Liu M, Han B, Meng Y, Xu X, Song Z, Liu X, Hao Q, Duan X, Nakai A, Chang Y, Cao P, Tan K
British journal of pharmacology 2021 Mar;178(5):1182-1199
British journal of pharmacology 2021 Mar;178(5):1182-1199
Tolerable upper intake level of iron damages the liver of weaned piglets.
Ding H, Zhao Y, Yu X, Chen L, Han J, Feng J
Journal of animal physiology and animal nutrition 2021 Jul;105(4):668-677
Journal of animal physiology and animal nutrition 2021 Jul;105(4):668-677
Tetrachlorobenzoquinone exposure triggers ferroptosis contributing to its neurotoxicity.
Liu Z, Lv X, Yang B, Qin Q, Song E, Song Y
Chemosphere 2021 Feb;264(Pt 1):128413
Chemosphere 2021 Feb;264(Pt 1):128413
LncRNA RP1-86C11.7 exacerbates the glioma progression and oncogenicity by hsa-miR-144-3p/TFRC signaling.
Ma Q, Wang X, Li J
Translational oncology 2021 Dec;14(12):101215
Translational oncology 2021 Dec;14(12):101215
Ferroptosis inducer erastin sensitizes NSCLC cells to celastrol through activation of the ROS-mitochondrial fission-mitophagy axis.
Liu M, Fan Y, Li D, Han B, Meng Y, Chen F, Liu T, Song Z, Han Y, Huang L, Chang Y, Cao P, Nakai A, Tan K
Molecular oncology 2021 Aug;15(8):2084-2105
Molecular oncology 2021 Aug;15(8):2084-2105
A novel signature constructed by ferroptosis-associated genes (FAGs) for the prediction of prognosis in bladder urothelial carcinoma (BLCA) and associated with immune infiltration.
Luan JC, Zeng TY, Zhang QJ, Xia DR, Cong R, Yao LY, Song LB, Zhou X, Zhou X, Chen X, Xia JD, Song NH
Cancer cell international 2021 Aug 6;21(1):414
Cancer cell international 2021 Aug 6;21(1):414
Fostered Nrf2 expression antagonizes iron overload and glutathione depletion to promote resistance of neuron-like cells to ferroptosis.
Liu Z, Lv X, Song E, Song Y
Toxicology and applied pharmacology 2020 Nov 15;407:115241
Toxicology and applied pharmacology 2020 Nov 15;407:115241
Transferrin receptor 1 targeted optical imaging for identifying glioma margin in mouse models.
Ni XR, Zhao YY, Cai HP, Yu ZH, Wang J, Chen FR, Yu YJ, Feng GK, Chen ZP
Journal of neuro-oncology 2020 Jun;148(2):245-258
Journal of neuro-oncology 2020 Jun;148(2):245-258
miR-30-5p-mediated ferroptosis of trophoblasts is implicated in the pathogenesis of preeclampsia.
Zhang H, He Y, Wang JX, Chen MH, Xu JJ, Jiang MH, Feng YL, Gu YF
Redox biology 2020 Jan;29:101402
Redox biology 2020 Jan;29:101402
A novel iron(II) phenanthroline complex exhibits anticancer activity against TFR1-overexpressing esophageal squamous cell carcinoma cells through ROS accumulation and DNA damage.
Ye J, Ma J, Liu C, Huang J, Wang L, Zhong X
Biochemical pharmacology 2019 Aug;166:93-107
Biochemical pharmacology 2019 Aug;166:93-107
Mutant huntingtin induces iron overload via up-regulating IRP1 in Huntington's disease.
Niu L, Ye C, Sun Y, Peng T, Yang S, Wang W, Li H
Cell & bioscience 2018;8:41
Cell & bioscience 2018;8:41
Retention of Mitochondria in Mature Human Red Blood Cells as the Result of Autophagy Impairment in Rett Syndrome.
Sbardella D, Tundo GR, Campagnolo L, Valacchi G, Orlandi A, Curatolo P, Borsellino G, D'Esposito M, Ciaccio C, Cesare SD, Pierro DD, Galasso C, Santarone ME, Hayek J, Coletta M, Marini S
Scientific reports 2017 Sep 26;7(1):12297
Scientific reports 2017 Sep 26;7(1):12297
FBW7 increases the chemosensitivity of pancreatic cancer cells to gemcitabine through upregulation of ENT1.
Hu Q, Qin Y, Zhang B, Liang C, Ji S, Shi S, Xu W, Xiang J, Liang D, Ni Q, Yu X, Xu J
Oncology reports 2017 Oct;38(4):2069-2077
Oncology reports 2017 Oct;38(4):2069-2077
Long-Term Dexamethasone Exposure Down-Regulates Hepatic TFR1 and Reduces Liver Iron Concentration in Rats.
Li H, Jiang S, Yang C, Yang S, He B, Ma W, Zhao R
Nutrients 2017 Jun 17;9(6)
Nutrients 2017 Jun 17;9(6)
Myricetin ameliorates scopolamine-induced memory impairment in mice via inhibiting acetylcholinesterase and down-regulating brain iron.
Wang B, Zhong Y, Gao C, Li J
Biochemical and biophysical research communications 2017 Aug 19;490(2):336-342
Biochemical and biophysical research communications 2017 Aug 19;490(2):336-342
Maternal protein restriction depresses the duodenal expression of iron transporters and serum iron level in male weaning piglets.
Ma W, Lu J, Jiang S, Cai D, Pan S, Jia Y, Zhao R
The British journal of nutrition 2017 Apr;117(7):923-929
The British journal of nutrition 2017 Apr;117(7):923-929
Intracellular Released Payload Influences Potency and Bystander-Killing Effects of Antibody-Drug Conjugates in Preclinical Models.
Li F, Emmerton KK, Jonas M, Zhang X, Miyamoto JB, Setter JR, Nicholas ND, Okeley NM, Lyon RP, Benjamin DR, Law CL
Cancer research 2016 May 1;76(9):2710-9
Cancer research 2016 May 1;76(9):2710-9
Liver metal levels and expression of genes related to iron homeostasis in rhesus monkeys after inhalational manganese exposure.
Pettiglio MA, Herrera C, Foster ML, Dorman DC, Bartnikas TB
Data in brief 2016 Mar;6:989-97
Data in brief 2016 Mar;6:989-97
Iron homeostasis and its disruption in mouse lung in iron deficiency and overload.
Giorgi G, D'Anna MC, Roque ME
Experimental physiology 2015 Oct;100(10):1199-216
Experimental physiology 2015 Oct;100(10):1199-216
Dysregulated iron metabolism in the choroid plexus in fragile X-associated tremor/ataxia syndrome.
Ariza J, Steward C, Rueckert F, Widdison M, Coffman R, Afjei A, Noctor SC, Hagerman R, Hagerman P, Martínez-Cerdeño V
Brain research 2015 Feb 19;1598:88-96
Brain research 2015 Feb 19;1598:88-96
Mono-ubiquitylated ORF45 Mediates Association of KSHV Particles with Internal Lipid Rafts for Viral Assembly and Egress.
Wang X, Zhu N, Li W, Zhu F, Wang Y, Yuan Y
PLoS pathogens 2015 Dec;11(12):e1005332
PLoS pathogens 2015 Dec;11(12):e1005332
Adaptor protein complex 2-mediated, clathrin-dependent endocytosis, and related gene activities, are a prominent feature during maturation stage amelogenesis.
Lacruz RS, Brookes SJ, Wen X, Jimenez JM, Vikman S, Hu P, White SN, Lyngstadaas SP, Okamoto CT, Smith CE, Paine ML
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2013 Mar;28(3):672-87
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2013 Mar;28(3):672-87
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K
Journal of proteomics 2013 Mar 27;80:171-82
Journal of proteomics 2013 Mar 27;80:171-82
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- MCF7 cells were subjected to SDS PAGE followed by western blot with 10084-2-AP(CD71 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human placenta using 10084-2-AP(CD71 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Transferrin receptor/CD71 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Transferrin receptor/CD71. This antibody recognizes human,mouse,rat antigen. The Transferrin receptor/CD71 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
