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antibody from Invitrogen Antibodies
Targeting: GDI1
FLJ41411, GDIL, MRX41, MRX48, OPHN2, RABGDIA, XAP-4
Western blot
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- Antibody Data
- Antigen structure
- References [13]
- Comments [0]
- Validations
- Other assay [4]
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- Product number
- 71-0300 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- GDI1 Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide
- Reactivity
- Human, Mouse, Rat, Bovine
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100 µg
- Concentration
- 0.25 mg/mL
- Storage
- -20°C
Submitted references Inhibiting glycolysis rescues memory impairment in an intellectual disability Gdi1-null mouse.
Inhibition of ER Stress by 2-Aminopurine Treatment Modulates Cardiomyopathy in a Murine Chronic Chagas Disease Model.
High fat diet aggravates cardiomyopathy in murine chronic Chagas disease.
Adipose Tissue Regulates Pulmonary Pathology during TB Infection.
Effect of Mycobacterium tuberculosis infection on adipocyte physiology.
Diet regulates liver autophagy differentially in murine acute Trypanosoma cruzi infection.
Antagonistic effect of atorvastatin on high fat diet induced survival during acute Chagas disease.
The transient expression of Klf4 and Klf5 during adipogenesis depends on GSK3β activity.
High fat diet modulates Trypanosoma cruzi infection associated myocarditis.
EPI64 protein functions as a physiological GTPase-activating protein for Rab27 protein and regulates amylase release in rat parotid acinar cells.
Syntaxin-6 SNARE involvement in secretory and endocytic pathways of cultured pancreatic beta-cells.
Deletion of the mental retardation gene Gdi1 impairs associative memory and alters social behavior in mice.
Estrogen lowers Alzheimer beta-amyloid generation by stimulating trans-Golgi network vesicle biogenesis.
D'Adamo P, Horvat A, Gurgone A, Mignogna ML, Bianchi V, Masetti M, Ripamonti M, Taverna S, Velebit J, Malnar M, Muhič M, Fink K, Bachi A, Restuccia U, Belloli S, Moresco RM, Mercalli A, Piemonti L, Potokar M, Bobnar ST, Kreft M, Chowdhury HH, Stenovec M, Vardjan N, Zorec R
Metabolism: clinical and experimental 2021 Mar;116:154463
Metabolism: clinical and experimental 2021 Mar;116:154463
Inhibition of ER Stress by 2-Aminopurine Treatment Modulates Cardiomyopathy in a Murine Chronic Chagas Disease Model.
Ayyappan JP, Lizardo K, Wang S, Yurkow E, Nagajyothi JF
Biomolecules & therapeutics 2019 Jul 1;27(4):386-394
Biomolecules & therapeutics 2019 Jul 1;27(4):386-394
High fat diet aggravates cardiomyopathy in murine chronic Chagas disease.
Lizardo K, Ayyappan JP, Cui MH, Balasubramanya R, Jelicks LA, Nagajyothi JF
Microbes and infection 2019 Jan-Feb;21(1):63-71
Microbes and infection 2019 Jan-Feb;21(1):63-71
Adipose Tissue Regulates Pulmonary Pathology during TB Infection.
Ayyappan JP, Ganapathi U, Lizardo K, Vinnard C, Subbian S, Perlin DS, Nagajyothi JF
mBio 2019 Apr 16;10(2)
mBio 2019 Apr 16;10(2)
Effect of Mycobacterium tuberculosis infection on adipocyte physiology.
Ayyappan JP, Vinnard C, Subbian S, Nagajyothi JF
Microbes and infection 2018 Feb;20(2):81-88
Microbes and infection 2018 Feb;20(2):81-88
Diet regulates liver autophagy differentially in murine acute Trypanosoma cruzi infection.
Lizardo K, Almonte V, Law C, Aiyyappan JP, Cui MH, Nagajyothi JF
Parasitology research 2017 Feb;116(2):711-723
Parasitology research 2017 Feb;116(2):711-723
Antagonistic effect of atorvastatin on high fat diet induced survival during acute Chagas disease.
Zhao D, Lizardo K, Cui MH, Ambadipudi K, Lora J, Jelicks LA, Nagajyothi JF
Microbes and infection 2016 Nov;18(11):675-686
Microbes and infection 2016 Nov;18(11):675-686
The transient expression of Klf4 and Klf5 during adipogenesis depends on GSK3β activity.
Cervantes-Camacho C, Beltrán-Langarica A, Ochoa-Uribe AK, Marsch-Moreno M, Ayala-Sumuano JT, Velez-delValle C, Kuri-Harcuch W
Adipocyte 2015 Oct-Dec;4(4):248-55
Adipocyte 2015 Oct-Dec;4(4):248-55
High fat diet modulates Trypanosoma cruzi infection associated myocarditis.
Nagajyothi F, Weiss LM, Zhao D, Koba W, Jelicks LA, Cui MH, Factor SM, Scherer PE, Tanowitz HB
PLoS neglected tropical diseases 2014 Oct;8(10):e3118
PLoS neglected tropical diseases 2014 Oct;8(10):e3118
EPI64 protein functions as a physiological GTPase-activating protein for Rab27 protein and regulates amylase release in rat parotid acinar cells.
Imai A, Yoshie S, Ishibashi K, Haga-Tsujimura M, Nashida T, Shimomura H, Fukuda M
The Journal of biological chemistry 2011 Sep 30;286(39):33854-62
The Journal of biological chemistry 2011 Sep 30;286(39):33854-62
Syntaxin-6 SNARE involvement in secretory and endocytic pathways of cultured pancreatic beta-cells.
Kuliawat R, Kalinina E, Bock J, Fricker L, McGraw TE, Kim SR, Zhong J, Scheller R, Arvan P
Molecular biology of the cell 2004 Apr;15(4):1690-701
Molecular biology of the cell 2004 Apr;15(4):1690-701
Deletion of the mental retardation gene Gdi1 impairs associative memory and alters social behavior in mice.
D'Adamo P, Welzl H, Papadimitriou S, Raffaele di Barletta M, Tiveron C, Tatangelo L, Pozzi L, Chapman PF, Knevett SG, Ramsay MF, Valtorta F, Leoni C, Menegon A, Wolfer DP, Lipp HP, Toniolo D
Human molecular genetics 2002 Oct 1;11(21):2567-80
Human molecular genetics 2002 Oct 1;11(21):2567-80
Estrogen lowers Alzheimer beta-amyloid generation by stimulating trans-Golgi network vesicle biogenesis.
Greenfield JP, Leung LW, Cai D, Kaasik K, Gross RS, Rodriguez-Boulan E, Greengard P, Xu H
The Journal of biological chemistry 2002 Apr 5;277(14):12128-36
The Journal of biological chemistry 2002 Apr 5;277(14):12128-36
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- NULL
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Figure 6 Immunoblot analysis of the hearts confirmed T. cruzi infection induced systemic alterations in lipid/cholesterol homeostasis and macrophage infiltration. Protein levels of LDLr and oxidized LDLr (LOX1), LPL, Abca1 and HMGCR were altered in the hearts during T. cruzi infection. Macrophage infiltration marker (F4/80) was significantly increased in the infected RD fed mice compared to infected HFD fed mice. Fold change in the protein levels were normalized to GDI expression and represented as bar graph (n = 5, p
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Figure 7 Immunoblot analysis of the WAT confirmed T. cruzi infection induced systemic alterations in lipid/cholesterol homeostasis. WAT from both the RD and HFD fed infected mice showed upregulated LDLr, Abca1 and LPL activity. Unlike hearts from the infected mice WAT showed no multimer adiponectin and also significantly reduced adiponectin monomers. Fold change in the protein levels were normalized to GDI expression and represented as bar graph (n = 5, p
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Figure 8 Immunoblot analysis of the hearts demonstrated altered adiponectin levels during acute T. cruzi infection. Immunoblot analysis demonstrated increased expression of adiponectin (multimer) in the hearts of infected mice compared to uninfected mice both in RD and HFD fed mice. Adiponectin monomer levels were significantly decreased in the hearts of infected mice. However, immunoblot analysis demonstrated significantly different levels of adiponectin levels between HFD and RD fed mice both at uninfected and infected conditions. Fold change in the protein levels were normalized to GDI expression and represented as bar graph (n = 5, p
