Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 20041-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#20041-1-AP, RRID:AB_10667456
- Product name
- ZC3H4 antibody
- Antibody type
- Polyclonal
- Description
- ZC3H4 antibody (Cat. #20041-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references CircDYM attenuates microglial apoptosis via CEBPB/ZC3H4 axis in LPS-induced mouse model of depression.
ZC3H4 governs epithelial cell migration through ROCK/p-PYK2/p-MLC2 pathway in silica-induced pulmonary fibrosis.
ARS2 instructs early transcription termination-coupled RNA decay by recruiting ZC3H4 to nascent transcripts.
ZC3H4 promotes pulmonary fibrosis via an ER stress-related positive feedback loop.
A missing piece of the puzzle in pulmonary fibrosis: anoikis resistance promotes fibroblast activation.
ZC3H4 mediates silica-induced EndoMT via ER stress and autophagy.
Elk-1 transcriptionally regulates ZC3H4 expression to promote silica-induced epithelial-mesenchymal transition.
The emerging roles of a novel CCCH-type zinc finger protein, ZC3H4, in silica-induced epithelial to mesenchymal transition.
Silica-induced initiation of circular ZC3H4 RNA/ZC3H4 pathway promotes the pulmonary macrophage activation.
Zhou Z, Ye Q, Ren H, Zhang Y, Han B, Yao H, Bai Y
International journal of biological macromolecules 2024 Jan;254(Pt 3):127922
International journal of biological macromolecules 2024 Jan;254(Pt 3):127922
ZC3H4 governs epithelial cell migration through ROCK/p-PYK2/p-MLC2 pathway in silica-induced pulmonary fibrosis.
Jiang R, Zhou Y, Gao Q, Han L, Hong Z
Environmental toxicology and pharmacology 2023 Nov;104:104301
Environmental toxicology and pharmacology 2023 Nov;104:104301
ARS2 instructs early transcription termination-coupled RNA decay by recruiting ZC3H4 to nascent transcripts.
Rouvière JO, Salerno-Kochan A, Lykke-Andersen S, Garland W, Dou Y, Rathore O, Molska EŠ, Wu G, Schmid M, Bugai A, Jakobsen L, Žumer K, Cramer P, Andersen JS, Conti E, Jensen TH
Molecular cell 2023 Jul 6;83(13):2240-2257.e6
Molecular cell 2023 Jul 6;83(13):2240-2257.e6
ZC3H4 promotes pulmonary fibrosis via an ER stress-related positive feedback loop.
Ghafoor H, Chu H, Huang J, Chen M, Wang S, Wang J, Chao J
Toxicology and applied pharmacology 2022 Jan 15;435:115856
Toxicology and applied pharmacology 2022 Jan 15;435:115856
A missing piece of the puzzle in pulmonary fibrosis: anoikis resistance promotes fibroblast activation.
Yin J, Wang J, Zhang X, Liao Y, Luo W, Wang S, Ding J, Huang J, Chen M, Wang W, Fang S, Chao J
Cell & bioscience 2022 Feb 25;12(1):21
Cell & bioscience 2022 Feb 25;12(1):21
ZC3H4 mediates silica-induced EndoMT via ER stress and autophagy.
Jiang R, Han L, Gao Q, Chao J
Environmental toxicology and pharmacology 2021 May;84:103605
Environmental toxicology and pharmacology 2021 May;84:103605
Elk-1 transcriptionally regulates ZC3H4 expression to promote silica-induced epithelial-mesenchymal transition.
Jiang R, Gao Q, Chen M, Yu T
Laboratory investigation; a journal of technical methods and pathology 2020 Jul;100(7):959-973
Laboratory investigation; a journal of technical methods and pathology 2020 Jul;100(7):959-973
The emerging roles of a novel CCCH-type zinc finger protein, ZC3H4, in silica-induced epithelial to mesenchymal transition.
Jiang R, Zhou Z, Liao Y, Yang F, Cheng Y, Huang J, Wang J, Chen H, Zhu T, Chao J
Toxicology letters 2019 Jun 1;307:26-40
Toxicology letters 2019 Jun 1;307:26-40
Silica-induced initiation of circular ZC3H4 RNA/ZC3H4 pathway promotes the pulmonary macrophage activation.
Yang X, Wang J, Zhou Z, Jiang R, Huang J, Chen L, Cao Z, Chu H, Han B, Cheng Y, Chao J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2018 Jun;32(6):3264-3277
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2018 Jun;32(6):3264-3277
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 20041-1-AP(ZC3H4 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Hela cells, using ZC3H4 antibody 210041-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human cervical cancer using 20041-1-AP(ZC3H4 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human cervical cancer using 20041-1-AP(ZC3H4 antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue