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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [4]
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- Validations
- Immunohistochemistry [2]
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- Product number
- MA1-06511 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- PKP3 Monoclonal Antibody (23E3/4)
- Antibody type
- Monoclonal
- Antigen
- Synthetic peptide
- Description
- MA1-06511 detects plakophilin-3 in human, mouse, canine cells.
- Antibody clone number
- 23E3/4
- Concentration
- 1 mg/mL
Submitted references Plakophilin3 loss leads to an increase in PRL3 levels promoting K8 dephosphorylation, which is required for transformation and metastasis.
Unimpaired skin carcinogenesis in Desmoglein 3 knockout mice.
E-cadherin and plakoglobin recruit plakophilin3 to the cell border to initiate desmosome assembly.
The transcription factor ZEB1 (deltaEF1) represses Plakophilin 3 during human cancer progression.
Khapare N, Kundu ST, Sehgal L, Sawant M, Priya R, Gosavi P, Gupta N, Alam H, Karkhanis M, Naik N, Vaidya MM, Dalal SN
PloS one 2012;7(6):e38561
PloS one 2012;7(6):e38561
Unimpaired skin carcinogenesis in Desmoglein 3 knockout mice.
Baron S, Hoang A, Vogel H, Attardi LD
PloS one 2012;7(11):e50024
PloS one 2012;7(11):e50024
E-cadherin and plakoglobin recruit plakophilin3 to the cell border to initiate desmosome assembly.
Gosavi P, Kundu ST, Khapare N, Sehgal L, Karkhanis MS, Dalal SN
Cellular and molecular life sciences : CMLS 2011 Apr;68(8):1439-54
Cellular and molecular life sciences : CMLS 2011 Apr;68(8):1439-54
The transcription factor ZEB1 (deltaEF1) represses Plakophilin 3 during human cancer progression.
Aigner K, Descovich L, Mikula M, Sultan A, Dampier B, Bonné S, van Roy F, Mikulits W, Schreiber M, Brabletz T, Sommergruber W, Schweifer N, Wernitznig A, Beug H, Foisner R, Eger A
FEBS letters 2007 Apr 17;581(8):1617-24
FEBS letters 2007 Apr 17;581(8):1617-24
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemistry analysis of PKP3 in hair root sheath of dog skin, using a PKP3 Monoclonal Antibody (23E3/4) (Product # MA1-06511)diluted 1:250.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemistry analysis of PKP3 in hair root sheath of dog skin, using a PKP3 Monoclonal Antibody (23E3/4) (Product # MA1-06511)diluted 1:250.
