24899-1-AP

antibody from Proteintech Group

Targeting: LRP5 BMND1, EVR1, EVR4, HBM, LR3, LRP7, OPPG, OPS, OPTA1, VBCH2

Provider product page for 24899-1-AP

Western blot

ELISA

Immunocytochemistry

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [17]
Comments [0]
Validations
Western blot [1]

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Product number: 24899-1-AP - Provider product page
Provider: Proteintech Group
Product name: LRP5 antibody
Antibody type: Polyclonal
Description: LRP5 antibody (Cat. #24899-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, WB,ELISA.
Reactivity: Human, Mouse
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

LRP5 protein structure - 24899-1-AP shown in red.

Submitted references Orally Administered Rhamnan Sulfate from Monostroma nitidum Significantly Inhibits Melanoma Metastasis in Lungs and Aorta of Mice Implanted with B16 Cells.

Hiramoto K, Imai M, Terasawa M, Suzuki K
Marine drugs 2026 Mar 29;24(4)

Late ad libitum feeding reverses early feed restriction-induced immune deficit in broilers.

Wang F, Feng J, Zhu Z, Nan S, Jing W, Yao M, Dou L, Wang D, Liu X, Sun X, Nie C
iScience 2026 Feb 20;29(2):114698

The BPIFA2 - LRP5 axis orchestrates mitochondrial dysfunction to mediate kidney injury in lupus nephritis.

Liu Y, Tian Y, Wang H, Li N, Zhuo R, Cui H, Miao X, Liu J, Liu Q, Zhang W, Guo H, Xing L, Yang L, Feng X, Liu S
International immunopharmacology 2025 Sep 23;162:115114

A Highly Bioactive Organic-Inorganic Nanoparticle for Activating Wnt10b Mediated Osteogenesis by Specifically Anchor CCN3 Protein.

Qiu Y, Wang C, Yang Y, Xu S, Huang H, Zhang L, Lei B, Zhao F
Advanced healthcare materials 2025 Mar;14(7):e2404075

Gut dysbiosis conveys psychological stress to activate LRP5/β-catenin pathway promoting cancer stemness.

Cui B, Luo H, He B, Liu X, Lv D, Zhang X, Su K, Zheng S, Lu J, Wang C, Yang Y, Zhao Z, Liu X, Wang X, Zhao Y, Nie X, Jiang Y, Zhang Z, Liu C, Chen X, Cai A, Lv Z, Liu Z, An F, Zhang Y, Yan Q, Kelley KW, Xu G, Xu L, Liu Q, Peng F
Signal transduction and targeted therapy 2025 Mar 5;10(1):79

CRTC2 Forms Co-Condensates with YTHDF2 That Enhance Translational Efficiency of m6A-Modified mRNAs to Drive Hepatocarcinogenesis and Lenvatinib Resistance.

Wang M, Zou F, Wang S, Yang Y, Xia C, Chen L, Liu B, Li L, Li MJ, Li H, Song W, Niu R, Yuan Z, Yang J, Li X, Chen K, Wu Z, Mi Z
Cancer research 2025 Jun 2;85(11):2046-2066

Mechanism of trypsin-mediated differentiation of pancreatic progenitor cells into functional islet-like clusters.

Gao L, Lai JS, Chen H, Qian LX, Hong WJ, Li LC
World journal of diabetes 2025 Jun 15;16(6):102727

Apigenin Alleviates Zearalenone-Induced Oxidative Stress and Apoptosis in Swine Testis Cells Through the Wnt Signaling Pathway.

Guo C, Zhang Y, Wang Y, Sun Y, Ning H, Gao J, Guo F, Ji P, Zhang L, Liu G, Wang B
Antioxidants (Basel, Switzerland) 2025 Dec 29;15(1)

Curcumin chitosan microspheres regulate Th17/Treg balance via IGF2BP1- mediated m6A modification of LRP5 in ulcerative colitis.

Chen L, Xiang Y, Zhong S, Wu Y, Liu J, Wu Y, Wang Z, Huang G
Iranian journal of basic medical sciences 2024;27(10):1276-1283

Pectolinarigenin ameliorates osteoporosis via enhancing Wnt signaling cascade in PPARβ-dependent manner.

Qian J, Li Q, Song Y, Gong X, Hu K, Ge G, Sun Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155587

Coenzyme Q10 Protects Against Hyperlipidemia-Induced Osteoporosis by Improving Mitochondrial Function via Modulating miR-130b-3p/PGC-1α Pathway.

Meng M, Wang J, Wang C, Zhao J, Wang H, Zhang Y, Sun H, Liu M
Calcified tissue international 2024 Feb;114(2):182-199

Lgr5-expressing secretory cells form a Wnt inhibitory niche in cartilage critical for chondrocyte identity.

Ruscitto A, Chen P, Tosa I, Wang Z, Zhou G, Safina I, Wei R, Morel MM, Koch A, Forman M, Reeve G, Lecholop MK, Wilson M, Bonthius D, Chen M, Ono M, Wang TC, Yao H, Embree MC
Cell stem cell 2023 Sep 7;30(9):1179-1198.e7

Babao Dan Alleviates 5-Fluorouracil-Induced Intestinal Damage via Wnt/β-Catenin Pathway.

Gui MX, Huang B, Peng J, Chen X, Muthu R, Gao Y, Wang RG, Lin JM
Chinese journal of integrative medicine 2022 Nov;28(11):1000-1006

LINC01119 negatively regulates osteogenic differentiation of mesenchymal stem cells via the Wnt pathway by targeting FZD4.

Gao H, Dong H, Zheng J, Jiang X, Gong M, Hu L, He J, Wang Y
Stem cell research & therapy 2022 Jan 29;13(1):43

Sini San Inhibits Chronic Psychological Stress-Induced Breast Cancer Stemness by Suppressing Cortisol-Mediated GRP78 Activation.

Zheng Y, Zhang J, Huang W, Zhong LLD, Wang N, Wang S, Yang B, Wang X, Pan B, Situ H, Lin Y, Liu X, Shi Y, Wang Z
Frontiers in pharmacology 2021;12:714163

Yiguanjian decoction inhibits macrophage M1 polarization and attenuates hepatic fibrosis induced by CCl(4)/2-AAF.

Xu Y, Xu W, Liu W, Chen G, Jiang S, Chen J, Jian X, Zhang H, Liu P, Mu Y
Pharmaceutical biology 2021 Dec;59(1):1150-1160

Wnt signaling pathway correlates with ossification of the spinal ligament: A microRNA array and immunohistochemical study.

Yayama T, Mori K, Okumura N, Nishizawa K, Kumagai K, Nakamura A, Imai S
Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association 2018 Jan;23(1):26-31

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: The LRP5 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human LRP5. This antibody recognizes human antigen. The LRP5 antibody has been validated for the following applications: ELISA, WB analysis.
Appendix: 24899-1-AP.pdf

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