abx117218

antibody from Abbexa

Targeting: UBB FLJ25987, MGC8385

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

abx117218

Provider

Abbexa

Product name

Polyubiquitin-B (UBB) Antibody

Antibody type

Polyclonal

Description

UBB Antibody is a Rabbit Polyclonal antibody against UBB. Ubiquitin can be covalently linked to many cellular proteins by the ubiquitination process, which targets proteins for degradation by the 26S proteasomeThree components are involved in the target protein-ubiquitin conjugation processUbiquitin is first activated by forming a thiolester complex with the ubiquitin-activating enzyme (UBE1 or E1)The activated ubiquitin is subsequently transferred to the ubiquitin-carrier protein E2, and then from E2 to ubiquitin ligase E3 for final delivery to the ε-amino group of the target protein lysine residueCombinatorial interactions of different E2 and E3 proteins result in substRate specificityUBE1 has two isofoms: UBE1a is a nuclear protein of 117 kDa while UBE1b is a nuclear and cytoplasmic protein of 110 kDa.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µg

Storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.