Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Immunohistochemistry [1]
- Flow cytometry [1]
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Validation data
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- Product number
- 10-3005 - Provider product page
- Provider
- ABEOMICS Inc.
- Product name
- Anti-TLR8/CD288 Antibody
- Antibody type
- Monoclonal
- Description
- Toll like receptor 8, also known as CD288, is a member of TLR family. It plays an important role in sensing phagocytosed pathogen. TLR8 recognizes ssRNA and recruits MyD88 and leads to the activation of transcription factor NF-kappa B. TLR8 TLR8 has two splice variants, viz., TLR8v1 and TLR8v2 and one missense variant, termed G or A1G allele of TLR8. TLR8v1 has additional 19 amino acids in the N-terminus. It is predominantly expressed in lung and peripheral blood leukocytes.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Antigen sequence
A partial length recombinant TLR8 p
rotein (amino acids 750-900) was us
ed as the immunogen for this antibo
dy.- Isotype
- IgG
- Antibody clone number
- ABM15F6
- Vial size
- 100 µg
- Concentration
- 0.5 mg/ml
- Storage
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freez thawing
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Supportive validation
- Submitted by
- ABEOMICS Inc. (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of TLR8 in small cell carcinoma of esophagus using TLR8 antibody (Clone: ABM15F6) at 5 µg/ml.
- Protocol
- Protocol
Supportive validation
- Submitted by
- ABEOMICS Inc. (provider)
- Main image
- Experimental details
- Intracellular flow analysis of hTLR8 in U937 using 2 µg/10^6 cells of hTLR8 antibody (Clone: ABM15F6). Green represents isotype control; red represents anti-hTLR8 antibody. Goat anti-mouse PE conjugate was used as secondary.
- Protocol
- Protocol