Antibody data

Product number
10-3005-25 - Provider product page
Provider
ABEOMICS Inc.
Product name
Anti-TLR8/CD288 Antibody
Antibody type
Monoclonal
Description
Toll like receptor 8, also known as CD288, is a member of TLR family. It plays an important role in sensing phagocytosed pathogen. TLR8 recognizes ssRNA and recruits MyD88 and leads to the activation of transcription factor NF-kappa B. TLR8 TLR8 has two splice variants, viz., TLR8v1 and TLR8v2 and one missense variant, termed G or A1G allele of TLR8. TLR8v1 has additional 19 amino acids in the N-terminus. It is predominantly expressed in lung and peripheral blood leukocytes.
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Antigen sequence
A partial length recombinant TLR8 p
rotein (amino acids 750-900) was us
ed as the immunogen for this antibo
dy.
Isotype
IgG
Antibody clone number
ABM15F6
Vial size
100 µg
Concentration
0.5 mg/ml
Storage
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freez thawing
TLR8 protein structure - 10-3005-25 shown in red.