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- Antibody Data
- Antigen structure
- References [14]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Flow cytometry [1]
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- Product number
- 16669-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16669-1-AP, RRID:AB_10598004
- Product name
- CD3 Delta antibody
- Antibody type
- Polyclonal
- Description
- CD3 Delta antibody (Cat. #16669-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Identification of a Gene Expression Signature to Predict the Risk of Abdominal Aortic Aneurysm in Psoriasis Patients.
Oxygen-delivery nanoparticles enhanced immunotherapy efficacy monitored by granzyme B PET imaging in malignant tumors.
Single-cell transcriptomic analysis of the senescent microenvironment in bone metastasis.
Trim21 modulates endoplasmic reticulum-associated degradation and sensitizes cancer cells to ER stress-induced apoptosis by inhibiting VCP/Npl4/UFD1 assembly.
Development of a novel CD3ε-specific human antibody for selective modulation of T cell activation.
A novel FITC.Chimeric antigen receptor-T cell targeting HIV-1-infected cells with FITC-conjugated antibodies for enhanced cytotoxicity.
NAD(+) Metabolism-Mediated SURF4-STING Axis Enhances T-Cell Anti-Tumor Effects in the Ovarian Cancer Microenvironment.
Glycyrrhiza polysaccharides may have an antitumor effect in γδT cells through gut microbiota and TLRs/NF-κB pathway in mice.
Testosterone upregulates glial cell line-derived neurotrophic factor (GDNF) and promotes neuroinflammation to enhance glioma cell survival and proliferation.
Single-cell transcriptomics reveals intestinal cell heterogeneity and identifies Ep300 as a potential therapeutic target in mice with acute liver failure.
cis interaction of CD153 with TCR/CD3 is crucial for the pathogenic activation of senescence-associated T cells.
Diagnostic utility of the aberrant immunohistochemical expression of CD3 molecules for peripheral T-cell lymphomas.
Epigenetic Regulation of CXCL12 Plays a Critical Role in Mediating Tumor Progression and the Immune Response In Osteosarcoma.
Changes in Expression of Genes Representing Key Biologic Processes after Neoadjuvant Chemotherapy in Breast Cancer, and Prognostic Implications in Residual Disease.
Lyu X, Tang Q, Zou Y, Liu X
Clinical, cosmetic and investigational dermatology 2025;18:961-978
Clinical, cosmetic and investigational dermatology 2025;18:961-978
Oxygen-delivery nanoparticles enhanced immunotherapy efficacy monitored by granzyme B PET imaging in malignant tumors.
Wang X, Fang H, Hu W, Feng Y, Zhou Z, Hu M, Jiang D, Zhang Y, Lan X
Journal of nanobiotechnology 2025 Mar 7;23(1):186
Journal of nanobiotechnology 2025 Mar 7;23(1):186
Single-cell transcriptomic analysis of the senescent microenvironment in bone metastasis.
Wang S, Ao L, Lin H, Wei H, Wu Z, Lu S, Liang F, Shen R, Zhang H, Miao T, Shen X, Lin J, Zhong G
Cell proliferation 2025 Jan;58(1):e13743
Cell proliferation 2025 Jan;58(1):e13743
Trim21 modulates endoplasmic reticulum-associated degradation and sensitizes cancer cells to ER stress-induced apoptosis by inhibiting VCP/Npl4/UFD1 assembly.
Yuan C, Liao Y, Si W, Huang M, Li D, Wang F, Quan Y, Yu X, Liao S
Biochimica et biophysica acta. Molecular basis of disease 2025 Jan;1871(1):167533
Biochimica et biophysica acta. Molecular basis of disease 2025 Jan;1871(1):167533
Development of a novel CD3ε-specific human antibody for selective modulation of T cell activation.
Yang HR, Kim JW, Choi HL, Shim H, Lee S
International journal of biological macromolecules 2025 Aug;320(Pt 2):145859
International journal of biological macromolecules 2025 Aug;320(Pt 2):145859
A novel FITC.Chimeric antigen receptor-T cell targeting HIV-1-infected cells with FITC-conjugated antibodies for enhanced cytotoxicity.
Mi Z, Chen J, Huan C, Zheng B, Yang W, Deng K, Zhao J, Huang J, Wang H, Du N, Zhang W
International journal of biological macromolecules 2025 Aug;319(Pt 4):145715
International journal of biological macromolecules 2025 Aug;319(Pt 4):145715
NAD(+) Metabolism-Mediated SURF4-STING Axis Enhances T-Cell Anti-Tumor Effects in the Ovarian Cancer Microenvironment.
Shen J, Xu F, Liu T, Ye Y, Xu S
Cell death & disease 2025 Aug 23;16(1):640
Cell death & disease 2025 Aug 23;16(1):640
Glycyrrhiza polysaccharides may have an antitumor effect in γδT cells through gut microbiota and TLRs/NF-κB pathway in mice.
Chen Y, Li Z, Bai L, Lu B, Peng Y, Xu P, Song X, Bian Y, Wang X, Zhao S
FEBS open bio 2024 Jun;14(6):1011-1027
FEBS open bio 2024 Jun;14(6):1011-1027
Testosterone upregulates glial cell line-derived neurotrophic factor (GDNF) and promotes neuroinflammation to enhance glioma cell survival and proliferation.
Kanwore K, Kanwore K, Guo X, Xia Y, Zhou H, Zhang L, Adzika GK, Joseph AA, Abiola AA, Mu P, Kambey PA, Noah MLN, Gao D
Inflammation and regeneration 2023 Oct 13;43(1):49
Inflammation and regeneration 2023 Oct 13;43(1):49
Single-cell transcriptomics reveals intestinal cell heterogeneity and identifies Ep300 as a potential therapeutic target in mice with acute liver failure.
Yin J, Zhao Z, Huang J, Xiao Y, Rehmutulla M, Zhang B, Zhang Z, Xiang M, Tong Q, Zhang Y
Cell discovery 2023 Jul 25;9(1):77
Cell discovery 2023 Jul 25;9(1):77
cis interaction of CD153 with TCR/CD3 is crucial for the pathogenic activation of senescence-associated T cells.
Fukushima Y, Sakamoto K, Matsuda M, Yoshikai Y, Yagita H, Kitamura D, Chihara M, Minato N, Hattori M
Cell reports 2022 Sep 20;40(12):111373
Cell reports 2022 Sep 20;40(12):111373
Diagnostic utility of the aberrant immunohistochemical expression of CD3 molecules for peripheral T-cell lymphomas.
Satoh T, Kayano H, Takahashi N, Tsukasaki K, Yasuda M
Annals of diagnostic pathology 2022 Oct;60:152013
Annals of diagnostic pathology 2022 Oct;60:152013
Epigenetic Regulation of CXCL12 Plays a Critical Role in Mediating Tumor Progression and the Immune Response In Osteosarcoma.
Li B, Wang Z, Wu H, Xue M, Lin P, Wang S, Lin N, Huang X, Pan W, Liu M, Yan X, Qu H, Sun L, Li H, Wu Y, Teng W, Wang Z, Zhou X, Chen H, Poznansky MC, Ye Z
Cancer research 2018 Jul 15;78(14):3938-3953
Cancer research 2018 Jul 15;78(14):3938-3953
Changes in Expression of Genes Representing Key Biologic Processes after Neoadjuvant Chemotherapy in Breast Cancer, and Prognostic Implications in Residual Disease.
Klintman M, Buus R, Cheang MC, Sheri A, Smith IE, Dowsett M
Clinical cancer research : an official journal of the American Association for Cancer Research 2016 May 15;22(10):2405-16
Clinical cancer research : an official journal of the American Association for Cancer Research 2016 May 15;22(10):2405-16
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Jurkat cells were subjected to SDS PAGE followed by western blot with 16669-1-AP(CD3D antibody) at dilution of 1:800
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using CD3D antibody 16669-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The CD3 delta antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human CD3 delta. This antibody recognizes human, mouse antigen. The CD3 delta antibody has been validated for the following applications: ELISA, WB, IHC, FC analysis.
