Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Flow cytometry [1]
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Validation data
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- Product number
- MHCD0322 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- CD3 Monoclonal Antibody (7D6), PE-Alexa Fluor™ 610
- Antibody type
- Monoclonal
- Antigen
- Other
- Description
- The R-phycoerythrin (PE)-Cy7® tandem conjugate permits simultaneous multicolor labeling and detection of multiple targets with excitation by a 488 nm laser without occupying traditional channels associated with FITC and PE.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 7D6
- Vial size
- 500 µL
- Storage
- 4° C, store in dark
Submitted references Intravesical Ty21a Vaccine Promotes Dendritic Cells and T Cell-Mediated Tumor Regression in the MB49 Bladder Cancer Model.
Tumour-derived PGD2 and NKp30-B7H6 engagement drives an immunosuppressive ILC2-MDSC axis.
ILC2-modulated T cell-to-MDSC balance is associated with bladder cancer recurrence.
Domingos-Pereira S, Sathiyanadan K, La Rosa S, Polák L, Chevalier MF, Martel P, Hojeij R, Derré L, Haefliger JA, Jichlinski P, Nardelli-Haefliger D
Cancer immunology research 2019 Apr;7(4):621-629
Cancer immunology research 2019 Apr;7(4):621-629
Tumour-derived PGD2 and NKp30-B7H6 engagement drives an immunosuppressive ILC2-MDSC axis.
Trabanelli S, Chevalier MF, Martinez-Usatorre A, Gomez-Cadena A, Salomé B, Lecciso M, Salvestrini V, Verdeil G, Racle J, Papayannidis C, Morita H, Pizzitola I, Grandclément C, Bohner P, Bruni E, Girotra M, Pallavi R, Falvo P, Leibundgut EO, Baerlocher GM, Carlo-Stella C, Taurino D, Santoro A, Spinelli O, Rambaldi A, Giarin E, Basso G, Tresoldi C, Ciceri F, Gfeller D, Akdis CA, Mazzarella L, Minucci S, Pelicci PG, Marcenaro E, McKenzie ANJ, Vanhecke D, Coukos G, Mavilio D, Curti A, Derré L, Jandus C
Nature communications 2017 Sep 19;8(1):593
Nature communications 2017 Sep 19;8(1):593
ILC2-modulated T cell-to-MDSC balance is associated with bladder cancer recurrence.
Chevalier MF, Trabanelli S, Racle J, Salomé B, Cesson V, Gharbi D, Bohner P, Domingos-Pereira S, Dartiguenave F, Fritschi AS, Speiser DE, Rentsch CA, Gfeller D, Jichlinski P, Nardelli-Haefliger D, Jandus C, Derré L
The Journal of clinical investigation 2017 Aug 1;127(8):2916-2929
The Journal of clinical investigation 2017 Aug 1;127(8):2916-2929
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Human peripheral blood lymphocytes stained using PE-Alexa Fluor® 610 of anti-human CD3 monoclonal antibody (clone S4.1). The negative control profiles represent unstained cells.